City Hill Ventures

City Hill Ventures, LLC is a San Diego-based investment firm established in 2010, specializing in seed and early-stage investments. The firm primarily focuses on the life sciences sector, including therapeutics, diagnostics, medical devices, and healthcare technology. Additionally, it seeks opportunities in clean technology, media, and entertainment. With its location in one of the world's leading life science clusters, City Hill Ventures aims to identify and support innovative private companies across the United States in these dynamic fields.

Jonathan Lim

Co-Founder

17 past transactions

Maze Therapeutics

Venture Round in 2022
Maze Therapeutics is a biotechnology firm based in South San Francisco, California, specializing in the research and development of genetic modifier therapeutics. Founded in 2017 and initially named Modulus Therapeutics, the company focuses on translating genetic insights into new medicines. It employs a combination of large-scale human genetics data analysis, functional genomics, and various drug discovery methods to identify modifier genes that provide protection against diseases. This innovative approach enhances the understanding of target biology and informs the development of targeted drug therapies, ultimately aiming to improve patient outcomes through the discovery of novel treatment options.

Viron Inc.

Series B in 2021
OncoMyx Therapeutics, Inc. is a biotechnology company specializing in the development of oncolytic immunotherapies utilizing the myxoma virus (MYXV) to stimulate immune responses against cancer. Founded in 2018 and based in Phoenix, Arizona, the company focuses on targeting both hematologic and solid tumors through its innovative MYXV platform. This platform employs a novel systemic delivery method that allows the myxoma virus to be carried by human leukocytes, enabling it to effectively infect tumor cells. By assembling a highly skilled team in oncolytic virus research, OncoMyx aims to advance a pipeline of therapeutic options designed to improve outcomes for cancer patients.

Viron Inc.

Series B in 2021
OncoMyx Therapeutics, Inc. is a biotechnology company specializing in the development of oncolytic immunotherapies utilizing the myxoma virus (MYXV) to stimulate immune responses against cancer. Founded in 2018 and based in Phoenix, Arizona, the company focuses on targeting both hematologic and solid tumors through its innovative MYXV platform. This platform employs a novel systemic delivery method that allows the myxoma virus to be carried by human leukocytes, enabling it to effectively infect tumor cells. By assembling a highly skilled team in oncolytic virus research, OncoMyx aims to advance a pipeline of therapeutic options designed to improve outcomes for cancer patients.

Erasca

Series B in 2020
Erasca develops oncology drugs intended to provide precision oncology options. The company's drugs are being developed through multiple discovery programs for undisclosed targets that are biological drivers of cancer and are pursuing additional opportunities for pipeline expansion through academic and biopharmaceutical collaborations, providing patients with new potential solutions to not just treat but cure cancer. It was founded in 2018 and headquartered in San Diego, California.

Maze Therapeutics

Venture Round in 2019
Maze Therapeutics is a biotechnology firm based in South San Francisco, California, specializing in the research and development of genetic modifier therapeutics. Founded in 2017 and initially named Modulus Therapeutics, the company focuses on translating genetic insights into new medicines. It employs a combination of large-scale human genetics data analysis, functional genomics, and various drug discovery methods to identify modifier genes that provide protection against diseases. This innovative approach enhances the understanding of target biology and informs the development of targeted drug therapies, ultimately aiming to improve patient outcomes through the discovery of novel treatment options.

Boundless Bio

Series A in 2019
Boundless Bio, Inc., biopharma company, develops therapies and medicines for the treatment of cancers. It offers therapeutics based on extrachromosomal DNA (ecDNA) one of the drivers of the aggressive cancers, such as cancers characterized by high copy number amplification of oncogenes. The company was formerly known as Pretzel Therapeutics, Inc. Boundless Bio, Inc. was founded in 2018 and is based in LA Jolla, California.

Viron Inc.

Series A in 2019
OncoMyx Therapeutics, Inc. is a biotechnology company specializing in the development of oncolytic immunotherapies utilizing the myxoma virus (MYXV) to stimulate immune responses against cancer. Founded in 2018 and based in Phoenix, Arizona, the company focuses on targeting both hematologic and solid tumors through its innovative MYXV platform. This platform employs a novel systemic delivery method that allows the myxoma virus to be carried by human leukocytes, enabling it to effectively infect tumor cells. By assembling a highly skilled team in oncolytic virus research, OncoMyx aims to advance a pipeline of therapeutic options designed to improve outcomes for cancer patients.

Erasca

Series A in 2018
Erasca develops oncology drugs intended to provide precision oncology options. The company's drugs are being developed through multiple discovery programs for undisclosed targets that are biological drivers of cancer and are pursuing additional opportunities for pipeline expansion through academic and biopharmaceutical collaborations, providing patients with new potential solutions to not just treat but cure cancer. It was founded in 2018 and headquartered in San Diego, California.

Bonti

Series C in 2018
Bonti, Inc. is a biotechnology company focused on developing neurotoxin products for both aesthetic and therapeutic uses. The company specializes in botulinum neurotoxin serotype E, with its primary products being EB-001A for aesthetic applications and EB-001T for therapeutic purposes. Originally founded as Endurance Biotech in 2015, the company rebranded to Bonti, Inc. in August of the same year. Based in Newport Beach, California, Bonti operates as a subsidiary of Allergan plc as of October 2018. The founding team includes Fauad Hasan, Mike Jarpe, Susan Abushakra, and Wajdie Ahmad.

Bonti

Series B in 2017
Bonti, Inc. is a biotechnology company focused on developing neurotoxin products for both aesthetic and therapeutic uses. The company specializes in botulinum neurotoxin serotype E, with its primary products being EB-001A for aesthetic applications and EB-001T for therapeutic purposes. Originally founded as Endurance Biotech in 2015, the company rebranded to Bonti, Inc. in August of the same year. Based in Newport Beach, California, Bonti operates as a subsidiary of Allergan plc as of October 2018. The founding team includes Fauad Hasan, Mike Jarpe, Susan Abushakra, and Wajdie Ahmad.

Flex Pharma

Venture Round in 2014
Flex Pharma, Inc. is a biotechnology company that is developing innovative and proprietary treatments for nocturnal leg cramps, cramps and spasms associated.

Independa

Series B in 2014
Independa, Inc. specializes in developing cloud-based wellness and social engagement software solutions tailored for senior citizens. The company's offerings include the AnyTV Companion, a remote care platform that facilitates social engagement and provides essential reminders for medications and appointments, as well as CloudCare, an enterprise solution that encompasses various modules for remote care, wellness, and community involvement. Independa also offers a caregiver dashboard that enables both professional and personal caregivers to monitor the needs of care recipients effectively. Additionally, its solutions feature smart reminders, broadcast messaging for alerts and notifications, and integrated monitoring that connects health devices and home sensors to ensure the safety and well-being of seniors. Founded in 2009 and headquartered in San Diego, California, Independa serves a diverse clientele, including senior living communities, rehabilitation centers, hospitals, insurance companies, and home care organizations. The company has established a strategic partnership with LG Electronics to enhance its service offerings.

Independa

Series A in 2013
Independa, Inc. specializes in developing cloud-based wellness and social engagement software solutions tailored for senior citizens. The company's offerings include the AnyTV Companion, a remote care platform that facilitates social engagement and provides essential reminders for medications and appointments, as well as CloudCare, an enterprise solution that encompasses various modules for remote care, wellness, and community involvement. Independa also offers a caregiver dashboard that enables both professional and personal caregivers to monitor the needs of care recipients effectively. Additionally, its solutions feature smart reminders, broadcast messaging for alerts and notifications, and integrated monitoring that connects health devices and home sensors to ensure the safety and well-being of seniors. Founded in 2009 and headquartered in San Diego, California, Independa serves a diverse clientele, including senior living communities, rehabilitation centers, hospitals, insurance companies, and home care organizations. The company has established a strategic partnership with LG Electronics to enhance its service offerings.

Ignyta

Series B in 2012
Ignyta is a scientifically-driven biotechnology company catalyzing personalized medicine in autoimmune diseases. Their goal is to revolutionize the quality of biomarkers and tests available to rheumatologists and patients to help them make better informed, more individualized treatment decisions; and to identify truly novel autoimmune disease targets for biopharmaceutical companies to enable the development of precise therapies for patients worldwide. Ignyta was incorporated in 2011 and operates in San Diego, California.

Independa

Venture Round in 2012
Independa, Inc. specializes in developing cloud-based wellness and social engagement software solutions tailored for senior citizens. The company's offerings include the AnyTV Companion, a remote care platform that facilitates social engagement and provides essential reminders for medications and appointments, as well as CloudCare, an enterprise solution that encompasses various modules for remote care, wellness, and community involvement. Independa also offers a caregiver dashboard that enables both professional and personal caregivers to monitor the needs of care recipients effectively. Additionally, its solutions feature smart reminders, broadcast messaging for alerts and notifications, and integrated monitoring that connects health devices and home sensors to ensure the safety and well-being of seniors. Founded in 2009 and headquartered in San Diego, California, Independa serves a diverse clientele, including senior living communities, rehabilitation centers, hospitals, insurance companies, and home care organizations. The company has established a strategic partnership with LG Electronics to enhance its service offerings.

Eclipse Therapeutics

Seed Round in 2011
Eclipse Therapeutics, Inc. ("Eclipse") is a private biotechnology company dedicated to the discovery and development of therapeutics that target cancer stem cells (CSCs) and other forms of innovative cancer treatment.

Independa

Venture Round in 2011
Independa, Inc. specializes in developing cloud-based wellness and social engagement software solutions tailored for senior citizens. The company's offerings include the AnyTV Companion, a remote care platform that facilitates social engagement and provides essential reminders for medications and appointments, as well as CloudCare, an enterprise solution that encompasses various modules for remote care, wellness, and community involvement. Independa also offers a caregiver dashboard that enables both professional and personal caregivers to monitor the needs of care recipients effectively. Additionally, its solutions feature smart reminders, broadcast messaging for alerts and notifications, and integrated monitoring that connects health devices and home sensors to ensure the safety and well-being of seniors. Founded in 2009 and headquartered in San Diego, California, Independa serves a diverse clientele, including senior living communities, rehabilitation centers, hospitals, insurance companies, and home care organizations. The company has established a strategic partnership with LG Electronics to enhance its service offerings.
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