SOSV is a global venture capital firm founded in 1995 and headquartered in Princeton, New Jersey. Specializing in seed-to-growth stage investments, SOSV operates multiple accelerator programs worldwide, including HAX for hardware, IndieBio and RebelBio for life sciences, Chinaccelerator and MOX for cross-border internet ventures, Food-X for innovative food solutions, and dlab for blockchain technology. The firm focuses on investments in revolutionary deep technologies aimed at improving human and planetary health, as well as cross-border markets, particularly in Asia. SOSV invests in approximately 150 startups annually, providing support through its resources to accelerate product development and scaling. Over its two-decade history, SOSV has established a strong reputation, consistently ranking among the top venture capital firms globally.
Unspun, Inc. is a technology-driven company based in San Francisco, California, specializing in the production of customized jeans using advanced body scanning technology and fit algorithms. Founded in 2015, Unspun aims to revolutionize the apparel industry by reducing global carbon emissions through automated and localized manufacturing processes. The company offers a B2B software platform that enables digital customization for various large apparel brands. Recognized for its innovation, Unspun's technology was featured in TIME's list of Best Inventions of 2019. The company is supported by several notable investors and is actively working on the future of additive and automated apparel production, positioning itself as a leader in the quest for sustainable fashion.
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes proprietary technology to deliver therapeutic DNA directly to intestinal stem cells, aiming to address the underlying causes of diseases such as Familial Adenomatous Polyposis (FAP), a hereditary form of colorectal cancer that often necessitates invasive surgical procedures. By targeting these root causes, DNALite seeks to prevent disease progression rather than merely managing symptoms, offering a potentially transformative approach to treating gastrointestinal disorders, including colorectal cancer and Crohn's disease.
Genetsis Group operates as a digital marketing agency, specializing in marketing strategy, development, and management in digital environments. The company provides a range of services, including data marketing, CRM strategy and activation, business intelligence, e-commerce optimization, and marketing automation. Additionally, Genetsis Group offers digital agency services such as campaign strategy, design and user experience, social media management, mobile development, and analytics. The firm is focused on delivering integrated digital communication and multiplatform interactive design, while also assisting businesses in executing digital transformation strategies to enhance customer experiences and improve operational efficiency. Founded in 1994, Genetsis Group is headquartered in Alcobendas, Spain, with additional offices in Shanghai, San Francisco, and Mexico City.
Tensorfield Agriculture develops and manufactures advanced agricultural machinery specifically for specialty row crops. Founded in 2018 and based in San Jose, California, the company focuses on innovative solutions to address challenges in modern farming practices. Its product lineup includes collaborative robots equipped with computer vision technology, which perform selective, non-invasive weeding without the use of herbicides. By utilizing thermal micro-dosing techniques, these robots help farmers combat herbicide resistance and support the sustainable production of safe, fresh food. Tensorfield Agriculture is supported by the HAX hardware accelerator and has received investment from the global venture capital firm SOSV.
Mirá Biotech is a biotechnology company focused on the development of sustainable, formaldehyde-free engineered wood products. By utilizing waste materials, such as sugar cane bagasse, the company aims to create all-natural alternatives to traditional wood boards, thereby promoting a circular economy. This innovative approach not only eliminates the need for tree harvesting but also contributes to sustainable industrial practices, positioning Mirá Biotech as a leader in environmentally friendly manufacturing solutions.
Prellis Biologics is building human tissues for drug development, and ultimately, developing human organs for transplantation. Bioprinting vascularized human tissue and organs will revolutionize healthcare. Prellis Biologics' technology leverages massive gains in print speed and resolution to break the microvasculature barrier.
Ria Health is a telehealth provider focused on treating alcohol use disorders through a mobile platform. Founded in 2013 and based in San Francisco, California, the company connects users with addiction specialists for personalized support and guidance. Ria Health employs evidence-based protocols, including medication-assisted treatment, harm reduction, and cognitive behavioral therapy, to assist heavy drinkers seeking to reduce or stop their alcohol consumption. The Ria app facilitates secure, HIPAA-compliant interactions, allowing for video and phone consultations, breathalyzer measurements, and progress tracking. By offering a private and convenient treatment option, Ria Health aims to address the significant gap in care for individuals struggling with alcohol-related issues, ensuring effective and affordable support that aligns with payer objectives.
BioLumen is a nutritional technology company that develops a patented dietary fiber technology platform that reduces the negative effect of a diet heavy in processed foods. BioLumen's technology is composed of insoluble dietary fiber matrix covered with a blend of food ingredients created from the latest drug delivery system research. The company's product, a nutraceutical, focuses on high risk individuals with prediabetes to help manage blood sugar levels, protect their liver from excess sugar and feed their gut microbiome, delivering health benefits. BioLumen was founded on 2018 and is headquartered in San Francisco, California.
R-Zero Systems, Inc. is a San Francisco-based company founded in 2020 that specializes in developing hospital-grade disinfection devices aimed at reducing the transmission of pathogens in various environments. The company offers innovative solutions, including the R-Zero Arc, a UV-C disinfection device designed to sanitize both surfaces and air in dynamic spaces such as schools, restaurants, hotels, and other enterprises. R-Zero focuses on biosafety technologies that protect businesses and communities from infectious diseases, leveraging science-backed protocols to enhance cleanliness and safety. Its products are designed for ease of use, allowing cleaning crews to effectively disinfect large areas quickly, thereby mitigating the spread of viruses, including those responsible for COVID-19 and other illnesses.
Voyage Foods has made sustainable and scalable alternatives to foods that have current obstacles –environmental, social, and health alike. Our breakthrough technology provides endless opportunities to make delicious, nearly identical, versions of beloved foods, without compromising individual health or our planet. We replicated the world’s favorite foods so that we can all enjoy them, forever.
Planetarians is focused on developing innovative ingredient technology systems to create affordable and healthy plant-based proteins. The company aims to address the growing demand for alternative meats, projected to rise from 2% to 23% of consumption, by utilizing animal feed sources such as sunflower, corn DDGS, and pulses. Their approach skips traditional protein isolation methods, employing a unique process that combines solid-state fermentation and wet extrusion. This method not only enhances the protein quality and umami taste of their products but also reduces costs compared to conventional meat alternatives. Additionally, Planetarians utilizes by-products from vegetable oil extraction and beer fermentation, creating carbon-negative meat alternatives that can fortify various food products with natural protein and fiber.
Artyc specializes in cold shipping solutions for biotech, pharmaceutical, and medical goods. The company focuses on creating sustainable logistics by providing refrigerant-free, reusable, active cooling containers. These innovative containers are designed to decarbonize the cold chain, thereby promoting a more environmentally friendly logistics industry. By utilizing Artyc's containers, businesses can benefit from reduced shipping costs and enhanced temperature monitoring, ensuring that sensitive products are transported safely and efficiently.
Artyc specializes in cold shipping solutions for biotech, pharmaceutical, and medical goods. The company focuses on creating sustainable logistics by providing refrigerant-free, reusable, active cooling containers. These innovative containers are designed to decarbonize the cold chain, thereby promoting a more environmentally friendly logistics industry. By utilizing Artyc's containers, businesses can benefit from reduced shipping costs and enhanced temperature monitoring, ensuring that sensitive products are transported safely and efficiently.
AnimalBiome focuses on improving the gut health of dogs and cats in the United States that suffer from chronic digestive disorders. The company offers microbiome-based supplements and non-invasive diagnostic tools designed to identify imbalances in the gut microbiome. Utilizing deoxyribonucleic acid sequencing, AnimalBiome's diagnostic services assess the balance of gut bacteria, allowing pet owners to gain insights into their pets' gut health. This information enables tailored supplementation aimed at restoring gut balance, ultimately promoting a healthier and happier life for pets.
flair is a reimagining of how your hvac system should work. It understands where you are and how to make you most comfortable. It also understands where you aren't, saving energy and lowering your bills.
UPSIDE Foods, formerly known as Memphis Meats, is a company headquartered in San Francisco, California, that specializes in producing cultured meat directly from animal cells. Founded in 2015 by Uma Valeti and Nicholas Genovese, the company focuses on developing products such as hot dogs, sausages, burgers, and meatballs without the need to raise and slaughter animals. This innovative approach to meat production requires significantly less caloric input, water, land, and energy compared to traditional methods, while also aiming to provide consumers with cleaner meat products that are free from harmful chemicals.
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes proprietary technology to deliver therapeutic DNA directly to intestinal stem cells, aiming to address the underlying causes of diseases such as Familial Adenomatous Polyposis (FAP), a hereditary form of colorectal cancer that often necessitates invasive surgical procedures. By targeting these root causes, DNALite seeks to prevent disease progression rather than merely managing symptoms, offering a potentially transformative approach to treating gastrointestinal disorders, including colorectal cancer and Crohn's disease.
Novoloop focuses on upcycling plastic waste into high-performance materials, branded as OISTRE™, which are utilized in various applications such as footwear, automotive, and home products. The company transforms packaging waste into materials that perform comparably to traditional fossil fuel-derived products, incorporating up to 50% post-consumer recycled content. This process not only reduces carbon emissions by up to 45% but also employs a low-carbon manufacturing method known as ATOD™, which emphasizes sustainability without compromising quality. Founded in 2015 and based in Philadelphia, Novoloop aims to contribute to a circular economy by providing environmentally friendly alternatives in the materials industry.
Developer of a software engineering school and apprenticeship platform designed to facilitate training programs that develop technical skills for the students. The company's platform focuses on backend software engineering, artificial intelligence, machine learning, and software developers and operations, enabling people with training and skills to succeed professionally and create a learning community.
Finless Foods Inc. is a biotechnology company based in Emeryville, California, focused on producing sustainable seafood alternatives through cellular agriculture technologies. Founded in 2017, the company specializes in growing marine-animal cells to create seafood products, including bluefin tuna. Finless Foods aims to provide a healthier and environmentally friendly alternative to traditionally caught and farmed seafood, offering consumers a cost-effective option that does not compromise on taste or dietary preferences. The company's mission is to develop and mass manufacture innovative marine animal food products that promote sustainability and accessibility in the seafood market.
Stämm Biotech, founded in 2014 and based in San Francisco, California, specializes in innovative biomanufacturing solutions for the life sciences sector. The company has developed a novel bioproduction system that integrates microfluidics, electroporation, and robotics to address the challenges of scaling in the biotech industry. Stämm's flagship product, the Bioprocessor, is an all-in-one, plug-and-play desktop unit that significantly enhances productivity, being at least 70 times more efficient than conventional bioreactors. Additionally, Stämm offers a suite of products including an automated continuous batch system for microbial growth, tools for tracking biological variations, and systems for monitoring microorganisms to convert data into actionable insights. This technological advancement positions Stämm to unlock a substantial market opportunity in biomanufacturing over the next decade.
QuantumCyte, Inc. is a biotechnology company based in Sunnyvale, California, founded in 2014. It specializes in developing a cell analysis system designed to enhance drug efficacy predictions and advance cancer research. By analyzing large numbers of cells, QuantumCyte aims to deepen the understanding of immune system and cancer biology. The company utilizes artificial intelligence in its pathology technology platform to provide precise cellular data, facilitating single-cell analysis for healthcare providers. Its team comprises experts from various fields, including biology, high technology, and diagnostics, with backgrounds in esteemed organizations such as Stanford and Genentech. QuantumCyte has established strong collaborations with specialists in cancer and genomic sequencing to meet fundamental research needs and ensure the scalability of its products.
Leadoptik is a California-based company operating in stealth mode, focused on developing advanced miniature imaging technology for minimally invasive medical procedures. This innovative technology enhances surgeons' ability to view small objects with improved clarity compared to existing imaging systems, offering 3D navigation capabilities and high-resolution imaging. By facilitating the early detection of cancer in patients, Leadoptik aims to significantly improve surgical outcomes and patient care.
Avisa Myko Inc. is a biotechnology company based in San Francisco, California, that specializes in the production of natural soluble melanin through precision fermentation technology. This innovative approach allows the company to manufacture melanin at scale and at an affordable cost, ensuring high purity and ease of application across various industries. Avisa Myko's melanin serves multiple purposes, including protection against ionizing radiation and electricity generation, and is utilized in cosmetics, biomedicine, organic semiconductors, biosensors, and textiles. The company is also developing a prototype sunscreen that leverages its melanin as an ultraviolet blocker without relying on conventional chemical or mineral filters. Through its patented technology, Avisa Myko aims to improve human health and environmental sustainability by integrating melanin into products such as latex, fabrics, and laminated materials.
NovoNutrients is focused on converting industrial waste carbon dioxide emissions into high-value protein ingredients for food and animal feed. The company has developed a fermentation platform that utilizes proprietary microbes and advanced gas fermentation systems to transform CO2, along with hydrogen and oxygen, into complete and safe single-cell protein. This innovative approach not only provides sustainable protein sources to support a growing population but also plays a role in combating climate change through carbon capture and utilization. By addressing both food security and environmental sustainability, NovoNutrients aims to meet the increasing demand for alternative protein solutions.
Clarity Movement is a team of passionate engineers and scientists focused on making a positive impact in the world by tackling the global air pollution crisis. They leverage their expertise in air sensing technology, IoT devices, and data analytics to create solutions that empower communities to make more informed decisions and improve the quality of life. Having successfully developed the world’s most accurate low-cost particulate matter sensor, Clarity is now deploying the next generation of dense air quality monitoring networks around the world to build smarter cities through smarter data.
Endless West is a beverage startup using scientific production methods to create its own original blend of wines and spirits. Its winery uses molecules from plants, animals, and substances for taste, smell, and color and combines them to create sustainable wine without any grapes, yeast, or any kind of fermentation. The company's first product, Glyph, is the first aged-style spirit made using flavor and aroma molecules extracted from more efficient sources in nature. Glyph is made without aging or barreling which means significantly less wood, water, and land is used in its production process. Endless West was founded in 2015 and is headquartered in San Francisco, California.
Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.
Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.
Chronus Health, Inc. is focused on developing a portable diagnostic platform that delivers rapid point-of-care lab results, specifically for complete blood count and comprehensive metabolic panel tests. Founded in 2017 and headquartered in California, the company utilizes advanced microfluidics and semiconductor technology, combined with data analytics, to provide real-time diagnoses within minutes. This handheld device significantly enhances the ability of healthcare providers to access actionable data on-site, thereby improving patient outcomes and reducing the time to care. Chronus Health aims to transform the diagnostic process by enabling immediate treatment decisions based on accurate lab results.
Circularis Biotechnologies, Inc. is a biotechnology company established in 2014 and based in California. The company focuses on developing innovative methods to regulate gene expression, aiming to enhance the production yields of biotherapeutics. Circularis offers a range of products, including RACRE Variant Libraries, hCMV Variant Library, and T7 Variant Library, as well as services such as RACRE Enhancement, RACRE Discovery, RACRE Technology Access Program, and Ribozyme Analysis of Cis-Regulatory Elements. By improving the targeting of gene therapy and optimizing gene expression in under-researched organisms, Circularis seeks to advance the fields of gene therapy, biomanufacturing, and synthetic biology, ultimately benefiting medical practitioners and enhancing therapeutic outcomes.
ZymoChem, Inc. develops microbes and bioprocesses that enable production of chemicals from renewable sources, such as sugars. The company was founded in 2013 and is based in Emeryville, California.
Clara Foods Co. specializes in producing animal-free proteins and ingredients for the food and beverage industry. Founded in 2014 and based in South San Francisco, California, the company utilizes advanced fermentation techniques to create functional and nutritional proteins derived from microorganisms. This innovative approach allows Clara Foods to offer a sustainable alternative to traditional animal agriculture, focusing on products such as baking ingredients, nutritional supplements, and egg white substitutes that are free from pathogens and salmonella. Their egg white products are particularly suited for baking applications, including cakes, meringues, and macarons. Clara Foods aims to transform the food industry by providing healthier and more humane protein sources.
Lingrove, LLC, founded in 2014 and based in San Francisco, California, specializes in manufacturing bio-composite materials aimed at addressing the diminishing supply of traditional wood. The company produces Ekoa, a high-performance natural fiber composite made from flax linen fibers and resin derived from industrial waste. Ekoa is utilized in various applications, including the production of guitars and other musical instruments, as well as in commercial interiors, transportation, and construction. Lingrove's innovative products are designed to mimic the appearance of wood while being plant-based and non-wood, thereby contributing to the reduction of deforestation and minimizing embodied carbon in buildings. By offering sustainable, carbon-negative solutions, Lingrove supports industries such as furniture, transportation, music, and sports in creating products that meet performance standards while promoting environmental responsibility.
New Culture Inc. is a food and beverage company that specializes in producing cheese from protein using innovative methods. By employing microflora to create dairy proteins and dairy products, the company aims to revolutionize traditional cheese-making processes. Founded in 2018 and headquartered in San Francisco, California, New Culture is committed to developing sustainable and alternative cheese options that appeal to a growing market of health-conscious and environmentally aware consumers.
Gaia Laboratories revolutionizes cell production, creating powerful solutions for the defining challenges of time. The founding principles behind Gaia Laboratories are to combat climate change, enable space-food, and make cell therapy accessible to everyone.
Calyx is a material science and Internet of Things (IoT) platform company that leverages biological principles to develop low-cost and highly accurate sensors for real-time detection and analysis of air chemicals. Founded in 2014 and rebranded from BioInspira in 2019, Calyx serves various sectors, including industrial safety, healthcare, transportation, and food markets. The company's innovative sensor technology is designed to enhance monitoring applications, including health and air quality assessments, along with ensuring safety in natural gas infrastructure. Based in Berkeley, California, Calyx is focused on providing solutions that improve safety and efficiency across multiple industries.
Sundial Foods, founded in 2019 and headquartered in Berkeley, California, specializes in creating plant-based meat alternatives aimed at environmentally conscious consumers. The company employs a macro and microstructural engineering approach to develop products that closely mimic the look, texture, and taste of traditional meat, all while ensuring affordability and nutritional value. By utilizing familiar ingredients and straightforward production processes, Sundial Foods strives to make plant-based meats accessible to a wider audience. The company's mission is to encourage a shift towards sustainable eating habits, thereby reducing meat consumption and its associated environmental impacts.
Novoloop focuses on upcycling plastic waste into high-performance materials, branded as OISTRE™, which are utilized in various applications such as footwear, automotive, and home products. The company transforms packaging waste into materials that perform comparably to traditional fossil fuel-derived products, incorporating up to 50% post-consumer recycled content. This process not only reduces carbon emissions by up to 45% but also employs a low-carbon manufacturing method known as ATOD™, which emphasizes sustainability without compromising quality. Founded in 2015 and based in Philadelphia, Novoloop aims to contribute to a circular economy by providing environmentally friendly alternatives in the materials industry.
Particle Industries, Inc. is a provider of a comprehensive platform designed for the prototyping, scaling, and management of Internet of Things (IoT) products. The company offers a range of hardware development kits, including the Photon for Wi-Fi projects and the Electron for cellular-connected devices, along with various accessories like antennas and USB shields. Particle also delivers software tools such as Tinker, a mobile application for remote control, and Particle Build, a web-based development environment that allows users to write and deploy code easily. Its cloud platform facilitates secure interactions with connected devices through modern APIs, supporting developers in creating intelligent web services. With over 150,000 product builders across more than 170 countries, including notable clients like NASA and SpaceX, Particle has established itself as a key player in the IoT landscape. Founded in 2012 and headquartered in San Francisco, California, with an additional office in Shenzhen, China, the company has been recognized for its innovation and impact in the IoT sector.
Prothegen is a biotechnology company that develops cutting-edge medicines for precisely regulating cell death. The company is based in Palo Alto, California.
Prothegen is a biotechnology company that develops cutting-edge medicines for precisely regulating cell death. The company is based in Palo Alto, California.
New Culture Inc. is a food and beverage company that specializes in producing cheese from protein using innovative methods. By employing microflora to create dairy proteins and dairy products, the company aims to revolutionize traditional cheese-making processes. Founded in 2018 and headquartered in San Francisco, California, New Culture is committed to developing sustainable and alternative cheese options that appeal to a growing market of health-conscious and environmentally aware consumers.
Fleksy, Inc. designs and delivers keyboard software for mobile devices. Its keyboard systems are available on Google Play, App Store, and Galaxy Gear. Fleksy, Inc. was formerly known as Syntellia, Inc. The company was founded in 2011 and is based in San Francisco, California. As of June 15, 2016, Fleksy, Inc. operates as a subsidiary of Pinterest, Inc..
Smartex focuses on addressing significant challenges in the textile industry by leveraging advanced AI technology, specifically machine learning and computer vision. The company has developed a hardware-enabled software solution that detects textile defects and irregularities in real time. By implementing this innovative system, Smartex can halt production when defects are identified, thereby minimizing defective output and reducing textile waste. This proactive approach not only enhances production efficiency but also contributes to sustainability by lowering carbon dioxide emissions, energy consumption, and water usage. Moreover, Smartex provides factories with a user interface to monitor production statistics, further improving operational insights and decision-making capabilities.
Getaround, Inc. operates an online marketplace for peer-to-peer car sharing and local car rentals, allowing users to rent vehicles from people nearby. Founded in 2009 and headquartered in San Francisco, the platform offers a diverse range of vehicles, including convertibles, luxury cars, SUVs, and trucks, available for rent by the hour or day. Getaround's innovative technology, known as Getaround Connect, facilitates a seamless car-sharing experience by enabling users to unlock and access vehicles without needing to meet the car owner or handle physical keys. The service is designed to eliminate the traditional hassles associated with car rentals, such as waiting in line and completing paperwork. Getaround provides users with a $1 million insurance policy and 24/7 roadside assistance, making it a safe option for renters. The company operates in major metropolitan areas across the United States, helping individuals offset car ownership costs while promoting more sustainable transportation options.
Perfect Day, Inc. is a company that specializes in producing animal-free dairy products, including milk, cheese, yogurt, and ice creams. Founded in 2014 and headquartered in Emeryville, California, the company utilizes yeast fermentation of plant-based sugars to create dairy proteins that are nutritionally identical to those found in cow's milk. This innovative approach allows Perfect Day to offer products that replicate the taste, texture, and nutritional benefits of traditional dairy while avoiding the environmental and ethical concerns associated with animal agriculture. The company's offerings are sustainable, vegan, and free from antibiotics, cholesterol, and lactose, catering to consumers seeking healthier and more compassionate alternatives to conventional dairy.
New Age Meats is a biotechnology company based in San Francisco, California, founded in 2017. The company specializes in producing cultivated meat using an automated, data-driven platform and advanced stem cell technology. By growing meat from animal cells rather than relying on traditional animal slaughter, New Age Meats aims to create healthier and more sustainable meat alternatives.
Indee Labs is developing hardware for gene delivery. Our hardware is uniquely positioned for the efficient development and scalable manufacture of gene-modified cell therapies such as chimeric antigen receptor T cells.
The technology is being developed with the help of the Australian National Fabrication Facility. We are alumni of NSW Health, IndieBio, Y Combinator and MBC Biolabs (née QB3@953). We are opening up an office in Sydney and have lab space at Bonneville Labs in Berkeley.
ZymoChem, Inc. develops microbes and bioprocesses that enable production of chemicals from renewable sources, such as sugars. The company was founded in 2013 and is based in Emeryville, California.
Kegg is a health technology company based in San Francisco, California, founded in 2017. It specializes in developing a two-in-one device that combines fertility tracking with pelvic floor exercises. Kegg's primary product is an innovative fertility tracker that enhances the chances of natural conception by accurately detecting the fertile window and ovulation up to seven days in advance. The device achieves this by analyzing changes in cervical fluid, providing essential data that was previously difficult to obtain. This information empowers women to make informed decisions regarding their reproductive health, thereby improving diagnosis, monitoring, and treatment options.
Unspun, Inc. is a technology-driven company based in San Francisco, California, specializing in the production of customized jeans using advanced body scanning technology and fit algorithms. Founded in 2015, Unspun aims to revolutionize the apparel industry by reducing global carbon emissions through automated and localized manufacturing processes. The company offers a B2B software platform that enables digital customization for various large apparel brands. Recognized for its innovation, Unspun's technology was featured in TIME's list of Best Inventions of 2019. The company is supported by several notable investors and is actively working on the future of additive and automated apparel production, positioning itself as a leader in the quest for sustainable fashion.
Feel Therapeutics, based in San Francisco, is focused on transforming mental health management through its innovative digital precision medicine platform. The company has developed an emotion-sensing wristband and accompanying app that provide continuous monitoring and real-time personalized interventions for individuals experiencing anxiety and depression. This comprehensive solution includes the Feel Emotion Sensor, Feel App, Feel Therapist, and an Educational Program, all designed to leverage evidence-based behavioral techniques such as Cognitive Behavioral Therapy, Mindfulness, and Positive Psychology. By integrating proprietary medical-grade wearables and advanced algorithms, Feel Therapeutics aims to deliver objective data and passive monitoring, ultimately enhancing users' mental well-being and fostering lasting positive emotional habits.
Finless Foods Inc. is a biotechnology company based in Emeryville, California, focused on producing sustainable seafood alternatives through cellular agriculture technologies. Founded in 2017, the company specializes in growing marine-animal cells to create seafood products, including bluefin tuna. Finless Foods aims to provide a healthier and environmentally friendly alternative to traditionally caught and farmed seafood, offering consumers a cost-effective option that does not compromise on taste or dietary preferences. The company's mission is to develop and mass manufacture innovative marine animal food products that promote sustainability and accessibility in the seafood market.
Fleksy, Inc. designs and delivers keyboard software for mobile devices. Its keyboard systems are available on Google Play, App Store, and Galaxy Gear. Fleksy, Inc. was formerly known as Syntellia, Inc. The company was founded in 2011 and is based in San Francisco, California. As of June 15, 2016, Fleksy, Inc. operates as a subsidiary of Pinterest, Inc..
Advanced Microbubbles Inc specializes in the development of microbubbles, which serve as ultrasound contrast agents for targeted drug delivery. Founded in 2020 and based in Newark, California, the company offers a range of products, including size-isolated microbubbles and biotin- or streptavidin-tagged variants. These microbubbles are designed for applications in ultrasound imaging, noninvasive cancer surgery, and enhancing drug delivery across challenging biological barriers, such as the blood-brain barrier. By focusing on precision drug and gene delivery, Advanced Microbubbles aims to improve treatment outcomes and reduce side effects for patients with neurological conditions and cancer.
Protera Biosciences, Inc. specializes in the production of protein-based food ingredients, focusing on innovative solutions to enhance food quality and safety. Founded in 2015 and located in Sunnyvale, California, the company offers a range of products including Protera Guard, a clean label protein that extends shelf life and replaces chemical preservatives, and Protera Sense, a plant-based oil that improves food texture without the use of palm oil or trans fats. Additionally, Protera provides antioxidant proteins and foaming and emulsifying proteins suitable for various applications, such as bakery products, chocolate, ice cream, and plant-based meat alternatives. Utilizing a proprietary deep learning algorithm named MADI, Protera accelerates the design and development of high-value protein products and enzymes, allowing for rapid validation and collaboration with clients to scale production effectively while addressing ethical and environmental challenges in food manufacturing.
Filtricine, Inc. is a clinical-stage biotechnology company based in Santa Clara, California, focused on developing therapeutic products for cancer treatment. Founded in 2017, the company specializes in a novel nutrient modulation platform that targets and depletes essential nutrients critical for cancer cell growth. By exploiting the metabolic vulnerabilities of cancer cells, Filtricine aims to halt the spread of cancer without relying on traditional drug substances. This approach allows healthcare professionals to utilize targeted nutrient deprivation therapy to address a broad spectrum of cancers effectively.
Getaround, Inc. operates an online marketplace for peer-to-peer car sharing and local car rentals, allowing users to rent vehicles from people nearby. Founded in 2009 and headquartered in San Francisco, the platform offers a diverse range of vehicles, including convertibles, luxury cars, SUVs, and trucks, available for rent by the hour or day. Getaround's innovative technology, known as Getaround Connect, facilitates a seamless car-sharing experience by enabling users to unlock and access vehicles without needing to meet the car owner or handle physical keys. The service is designed to eliminate the traditional hassles associated with car rentals, such as waiting in line and completing paperwork. Getaround provides users with a $1 million insurance policy and 24/7 roadside assistance, making it a safe option for renters. The company operates in major metropolitan areas across the United States, helping individuals offset car ownership costs while promoting more sustainable transportation options.
Prellis Biologics is building human tissues for drug development, and ultimately, developing human organs for transplantation. Bioprinting vascularized human tissue and organs will revolutionize healthcare. Prellis Biologics' technology leverages massive gains in print speed and resolution to break the microvasculature barrier.
Velo Labs (DBA Lattis) is a smart city startup focused on improving urban living through intelligent technology solutions. Its first product, Ellipse, is a smart bicycle lock that provides theft alerts, keyless entry and solar charging.
Velo Labs (DBA Lattis) is a smart city startup focused on improving urban living through intelligent technology solutions. Its first product, Ellipse, is a smart bicycle lock that provides theft alerts, keyless entry and solar charging.
QuantumCyte, Inc. is a biotechnology company based in Sunnyvale, California, founded in 2014. It specializes in developing a cell analysis system designed to enhance drug efficacy predictions and advance cancer research. By analyzing large numbers of cells, QuantumCyte aims to deepen the understanding of immune system and cancer biology. The company utilizes artificial intelligence in its pathology technology platform to provide precise cellular data, facilitating single-cell analysis for healthcare providers. Its team comprises experts from various fields, including biology, high technology, and diagnostics, with backgrounds in esteemed organizations such as Stanford and Genentech. QuantumCyte has established strong collaborations with specialists in cancer and genomic sequencing to meet fundamental research needs and ensure the scalability of its products.
Sugarlogix is creating prebiotic sugars with functional benefits for your gut health. Found naturally in human breast milk, their functional sugars restore balance to the gut microbiome, thus enhancing the immune system and reducing inflammation.
AnimalBiome focuses on improving the gut health of dogs and cats in the United States that suffer from chronic digestive disorders. The company offers microbiome-based supplements and non-invasive diagnostic tools designed to identify imbalances in the gut microbiome. Utilizing deoxyribonucleic acid sequencing, AnimalBiome's diagnostic services assess the balance of gut bacteria, allowing pet owners to gain insights into their pets' gut health. This information enables tailored supplementation aimed at restoring gut balance, ultimately promoting a healthier and happier life for pets.
R-Zero Systems, Inc. is a San Francisco-based company founded in 2020 that specializes in developing hospital-grade disinfection devices aimed at reducing the transmission of pathogens in various environments. The company offers innovative solutions, including the R-Zero Arc, a UV-C disinfection device designed to sanitize both surfaces and air in dynamic spaces such as schools, restaurants, hotels, and other enterprises. R-Zero focuses on biosafety technologies that protect businesses and communities from infectious diseases, leveraging science-backed protocols to enhance cleanliness and safety. Its products are designed for ease of use, allowing cleaning crews to effectively disinfect large areas quickly, thereby mitigating the spread of viruses, including those responsible for COVID-19 and other illnesses.
Prellis Biologics is building human tissues for drug development, and ultimately, developing human organs for transplantation. Bioprinting vascularized human tissue and organs will revolutionize healthcare. Prellis Biologics' technology leverages massive gains in print speed and resolution to break the microvasculature barrier.
Mendel.ai develops artificial intelligence-based solutions aimed at enhancing clinical oncology research and improving patient care. Founded in 2005 and headquartered in San Jose, California, the company offers a range of software solutions that address various challenges in the clinical trial process. Its products include Read, which provides instant data abstraction; Retina, designed to minimize data loss during optical character recognition; Redact, which addresses privacy concerns in patient record sharing; Research, a clinical search engine; Recruit, facilitating patient prescreening and enrollment; and Enrich, which offers real-time access to real-world data from leading oncology clinics. By transforming unstructured electronic medical records and clinical literature into analytics-ready data, Mendel.ai aims to streamline global oncology research and automate clinical trials.
Oralta is a U.S.-based company that specializes in the manufacture of probiotic supplements aimed at improving oral health. Its flagship product, FRESH BREATH, consists of chewable tablets designed to combat bad breath by eliminating odor-causing bacteria while promoting the growth of beneficial probiotic strains. The tablets work by preventing the buildup of harmful germs, reducing their growth, and inactivating the byproducts responsible for unpleasant odors. Oralta's innovative approach focuses on restoring a healthy balance of oral bacteria, ultimately enhancing overall oral hygiene and addressing conditions such as tooth decay and gum disease.
Ria Health is a telehealth provider focused on treating alcohol use disorders through a mobile platform. Founded in 2013 and based in San Francisco, California, the company connects users with addiction specialists for personalized support and guidance. Ria Health employs evidence-based protocols, including medication-assisted treatment, harm reduction, and cognitive behavioral therapy, to assist heavy drinkers seeking to reduce or stop their alcohol consumption. The Ria app facilitates secure, HIPAA-compliant interactions, allowing for video and phone consultations, breathalyzer measurements, and progress tracking. By offering a private and convenient treatment option, Ria Health aims to address the significant gap in care for individuals struggling with alcohol-related issues, ensuring effective and affordable support that aligns with payer objectives.
Stämm Biotech, founded in 2014 and based in San Francisco, California, specializes in innovative biomanufacturing solutions for the life sciences sector. The company has developed a novel bioproduction system that integrates microfluidics, electroporation, and robotics to address the challenges of scaling in the biotech industry. Stämm's flagship product, the Bioprocessor, is an all-in-one, plug-and-play desktop unit that significantly enhances productivity, being at least 70 times more efficient than conventional bioreactors. Additionally, Stämm offers a suite of products including an automated continuous batch system for microbial growth, tools for tracking biological variations, and systems for monitoring microorganisms to convert data into actionable insights. This technological advancement positions Stämm to unlock a substantial market opportunity in biomanufacturing over the next decade.
Simbe Robotics, Inc. is a San Francisco-based company founded in 2014 that specializes in autonomous robotic solutions for the retail industry. Its flagship product, Tally, automates the tedious tasks of auditing store shelves, such as identifying out-of-stock and low-stock items, locating misplaced products, and detecting pricing errors. The robot operates safely during normal store hours, allowing it to navigate aisles alongside shoppers and employees. By capturing real-time inventory data, Tally enables retail staff to enhance operational efficiency and improve inventory management, ultimately streamlining store performance and supporting informed decision-making.
ViaBot Inc. designs and develops autonomous outdoor robots tailored for commercial properties, including sports arenas, shopping malls, and corporate buildings. The company's multi-functional robots are engineered to perform various outdoor maintenance tasks, such as sweeping, lawn mowing, and security monitoring. ViaBot's technology features modular capabilities, allowing for easy scheduling and long runtimes, while providing 24/7 operational efficiency and constant software updates. Incorporated in 2015 and headquartered in San Francisco, California, ViaBot aims to simplify outdoor maintenance for businesses by offering innovative robotic solutions.
Butlr Technologies Inc. develops a wireless sensor system that captures and transmits real-time data on human movement and behavior in various environments, particularly in retail and hospitality. Founded in 2019 and based in Burlingame, California, Butlr's technology combines proprietary hardware with advanced artificial intelligence to analyze location and duration data, translating it into insights about consumer preferences and behaviors. The company's low-cost thermal imaging system gained attention during the coronavirus pandemic as a tool to protect the health of employees and customers. Unlike traditional cameras, Butlr's sensors detect unique biometric heat signatures, allowing for privacy-preserving monitoring while enabling businesses to optimize their spaces. This technology has broader implications, with a vision for responsive architecture that adapts environments based on real-time data, potentially enhancing urban infrastructure by predicting and responding to dynamic conditions such as pedestrian traffic and weather changes.
Protera Biosciences, Inc. specializes in the production of protein-based food ingredients, focusing on innovative solutions to enhance food quality and safety. Founded in 2015 and located in Sunnyvale, California, the company offers a range of products including Protera Guard, a clean label protein that extends shelf life and replaces chemical preservatives, and Protera Sense, a plant-based oil that improves food texture without the use of palm oil or trans fats. Additionally, Protera provides antioxidant proteins and foaming and emulsifying proteins suitable for various applications, such as bakery products, chocolate, ice cream, and plant-based meat alternatives. Utilizing a proprietary deep learning algorithm named MADI, Protera accelerates the design and development of high-value protein products and enzymes, allowing for rapid validation and collaboration with clients to scale production effectively while addressing ethical and environmental challenges in food manufacturing.
Sundial Foods, founded in 2019 and headquartered in Berkeley, California, specializes in creating plant-based meat alternatives aimed at environmentally conscious consumers. The company employs a macro and microstructural engineering approach to develop products that closely mimic the look, texture, and taste of traditional meat, all while ensuring affordability and nutritional value. By utilizing familiar ingredients and straightforward production processes, Sundial Foods strives to make plant-based meats accessible to a wider audience. The company's mission is to encourage a shift towards sustainable eating habits, thereby reducing meat consumption and its associated environmental impacts.
Sundial Foods, founded in 2019 and headquartered in Berkeley, California, specializes in creating plant-based meat alternatives aimed at environmentally conscious consumers. The company employs a macro and microstructural engineering approach to develop products that closely mimic the look, texture, and taste of traditional meat, all while ensuring affordability and nutritional value. By utilizing familiar ingredients and straightforward production processes, Sundial Foods strives to make plant-based meats accessible to a wider audience. The company's mission is to encourage a shift towards sustainable eating habits, thereby reducing meat consumption and its associated environmental impacts.
flair is a reimagining of how your hvac system should work. It understands where you are and how to make you most comfortable. It also understands where you aren't, saving energy and lowering your bills.
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes proprietary technology to deliver therapeutic DNA directly to intestinal stem cells, aiming to address the underlying causes of diseases such as Familial Adenomatous Polyposis (FAP), a hereditary form of colorectal cancer that often necessitates invasive surgical procedures. By targeting these root causes, DNALite seeks to prevent disease progression rather than merely managing symptoms, offering a potentially transformative approach to treating gastrointestinal disorders, including colorectal cancer and Crohn's disease.
Endless West is a beverage startup using scientific production methods to create its own original blend of wines and spirits. Its winery uses molecules from plants, animals, and substances for taste, smell, and color and combines them to create sustainable wine without any grapes, yeast, or any kind of fermentation. The company's first product, Glyph, is the first aged-style spirit made using flavor and aroma molecules extracted from more efficient sources in nature. Glyph is made without aging or barreling which means significantly less wood, water, and land is used in its production process. Endless West was founded in 2015 and is headquartered in San Francisco, California.
Tensorfield Agriculture develops and manufactures advanced agricultural machinery specifically for specialty row crops. Founded in 2018 and based in San Jose, California, the company focuses on innovative solutions to address challenges in modern farming practices. Its product lineup includes collaborative robots equipped with computer vision technology, which perform selective, non-invasive weeding without the use of herbicides. By utilizing thermal micro-dosing techniques, these robots help farmers combat herbicide resistance and support the sustainable production of safe, fresh food. Tensorfield Agriculture is supported by the HAX hardware accelerator and has received investment from the global venture capital firm SOSV.
Gaia Laboratories revolutionizes cell production, creating powerful solutions for the defining challenges of time. The founding principles behind Gaia Laboratories are to combat climate change, enable space-food, and make cell therapy accessible to everyone.
Chronus Health, Inc. is focused on developing a portable diagnostic platform that delivers rapid point-of-care lab results, specifically for complete blood count and comprehensive metabolic panel tests. Founded in 2017 and headquartered in California, the company utilizes advanced microfluidics and semiconductor technology, combined with data analytics, to provide real-time diagnoses within minutes. This handheld device significantly enhances the ability of healthcare providers to access actionable data on-site, thereby improving patient outcomes and reducing the time to care. Chronus Health aims to transform the diagnostic process by enabling immediate treatment decisions based on accurate lab results.
Wayfinder Biosciences develops biosensors for ultra-high-throughput screening for high-value molecules. The company's PerfectPath biosensors make invisible molecules visible. These biosensors generate fluorescence based on the concentration of the desired small-molecule — allowing quantification of product titer at high-throughput using fast fluorescence measurements. Wayfinder Biosciences was established in 2021 and is headquartered in San Francisco, CA.
Wayfinder Biosciences develops biosensors for ultra-high-throughput screening for high-value molecules. The company's PerfectPath biosensors make invisible molecules visible. These biosensors generate fluorescence based on the concentration of the desired small-molecule — allowing quantification of product titer at high-throughput using fast fluorescence measurements. Wayfinder Biosciences was established in 2021 and is headquartered in San Francisco, CA.
Feel Therapeutics, based in San Francisco, is focused on transforming mental health management through its innovative digital precision medicine platform. The company has developed an emotion-sensing wristband and accompanying app that provide continuous monitoring and real-time personalized interventions for individuals experiencing anxiety and depression. This comprehensive solution includes the Feel Emotion Sensor, Feel App, Feel Therapist, and an Educational Program, all designed to leverage evidence-based behavioral techniques such as Cognitive Behavioral Therapy, Mindfulness, and Positive Psychology. By integrating proprietary medical-grade wearables and advanced algorithms, Feel Therapeutics aims to deliver objective data and passive monitoring, ultimately enhancing users' mental well-being and fostering lasting positive emotional habits.
Voyage Foods has made sustainable and scalable alternatives to foods that have current obstacles –environmental, social, and health alike. Our breakthrough technology provides endless opportunities to make delicious, nearly identical, versions of beloved foods, without compromising individual health or our planet. We replicated the world’s favorite foods so that we can all enjoy them, forever.
Huue, formerly known as Tinctorium Inc., is a biotechnology company based in Berkeley, California, specializing in sustainable indigo dyeing solutions for the textile and fashion industry. Founded in 2018, the company utilizes a unique technology that mimics natural plant processes within microbes to produce indigo dye. This innovative approach significantly reduces chemical usage in the denim supply chain, offering an environmentally friendly alternative for denim production. By harnessing the power of biotechnology, Huue aims to provide the fashion industry with sustainable coloring options that rely on renewable resources, contributing to a more eco-conscious approach in textile manufacturing.
Huue, formerly known as Tinctorium Inc., is a biotechnology company based in Berkeley, California, specializing in sustainable indigo dyeing solutions for the textile and fashion industry. Founded in 2018, the company utilizes a unique technology that mimics natural plant processes within microbes to produce indigo dye. This innovative approach significantly reduces chemical usage in the denim supply chain, offering an environmentally friendly alternative for denim production. By harnessing the power of biotechnology, Huue aims to provide the fashion industry with sustainable coloring options that rely on renewable resources, contributing to a more eco-conscious approach in textile manufacturing.
New Age Meats is a biotechnology company based in San Francisco, California, founded in 2017. The company specializes in producing cultivated meat using an automated, data-driven platform and advanced stem cell technology. By growing meat from animal cells rather than relying on traditional animal slaughter, New Age Meats aims to create healthier and more sustainable meat alternatives.
Aja Labs is a biotechnology company that produces biodegradable fiber intended to eliminate the usage of plastic-based fiber. They create solutions for the many dynamic and diverse communities with which they identify. The company uses plants to grow fiber that looks and feels like human hair, enabling people in eliminating the need for chemical-heavy synthetics or human hair in the production of hair extensions. Aja Labs was founded in 2019 and is headquartered in San Francisco, CA.
Aja Labs is a biotechnology company that produces biodegradable fiber intended to eliminate the usage of plastic-based fiber. They create solutions for the many dynamic and diverse communities with which they identify. The company uses plants to grow fiber that looks and feels like human hair, enabling people in eliminating the need for chemical-heavy synthetics or human hair in the production of hair extensions. Aja Labs was founded in 2019 and is headquartered in San Francisco, CA.
NovoNutrients is focused on converting industrial waste carbon dioxide emissions into high-value protein ingredients for food and animal feed. The company has developed a fermentation platform that utilizes proprietary microbes and advanced gas fermentation systems to transform CO2, along with hydrogen and oxygen, into complete and safe single-cell protein. This innovative approach not only provides sustainable protein sources to support a growing population but also plays a role in combating climate change through carbon capture and utilization. By addressing both food security and environmental sustainability, NovoNutrients aims to meet the increasing demand for alternative protein solutions.
Mimio Health
Seed Round in 2021
Mimio Health is a nutraceutical company focusing on the research and production of mimetic supplements. Its patent-pending fasting mimetic formulation uses a rigorously selected combination of the same bioactive human metabolites that induce this regenerative "bio-program" to replicate the body’s natural response to fasting without having to fast.
Mimio Health
Convertible Note in 2021
Mimio Health is a nutraceutical company focusing on the research and production of mimetic supplements. Its patent-pending fasting mimetic formulation uses a rigorously selected combination of the same bioactive human metabolites that induce this regenerative "bio-program" to replicate the body’s natural response to fasting without having to fast.
Elsa is a mobile application focused on English language pronunciation training and accent reduction. The platform employs artificial intelligence and speech recognition technology to deliver precise phoneme-level feedback to users, assisting them in improving their English pronunciation. By providing real-time phonetic instructions, Elsa enables language learners worldwide to identify and correct their pronunciation errors, ultimately fostering greater fluency and confidence in their spoken English.
Preemadonna is the maker of Nailbot, a patented nail robot and intelligent manicure product line disrupting the $15B nail care industry. Our first Nailbot prints art and photos directly on fingernails in 5 seconds. Future Nailbots print full polish.
Nailbot is powered by our art marketplace and community of makers who crave instant self expression, design digital art and love printing on the go with Nailbot. We will build other creative expression on demand printing and robotics products for our Preemadonna customer throughout her/his lifespan.
Lingrove, LLC, founded in 2014 and based in San Francisco, California, specializes in manufacturing bio-composite materials aimed at addressing the diminishing supply of traditional wood. The company produces Ekoa, a high-performance natural fiber composite made from flax linen fibers and resin derived from industrial waste. Ekoa is utilized in various applications, including the production of guitars and other musical instruments, as well as in commercial interiors, transportation, and construction. Lingrove's innovative products are designed to mimic the appearance of wood while being plant-based and non-wood, thereby contributing to the reduction of deforestation and minimizing embodied carbon in buildings. By offering sustainable, carbon-negative solutions, Lingrove supports industries such as furniture, transportation, music, and sports in creating products that meet performance standards while promoting environmental responsibility.
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