Immuto Scientific is a biotechnology services company that provides analytical insights to pharmaceutical companies for drug discovery.
Pyran LLC specializes in developing a starting compound for the production of paints and plastic chemicals. Founded in 2017 and based in Madison, Wisconsin, the company creates a diol product derived from renewable wood and crop waste resources. This diol serves as a raw material for various applications, including digital versatile discs, paints, bottles, coatings, plastics, ropes, glues, and adhesives. Pyran primarily caters to the chemical industries, focusing on sustainable solutions for paint and plastic manufacturing.
Developer of a cancer treatment system designed to simplify cancer radiation therapy. The company's system is integrated with a radiotherapy machine specializing in 3D image capturing, controlling radiation beams, and automatically delivering the right amount of energy to the right tissue, enabling patients to access and connect with a centralized cancer care center for cancer radiation therapies and reduce the pain and cost of chemo and radiation therapy.
OnLume, Inc. is a medical device company based in Madison, Wisconsin, founded in 2015. The company specializes in developing intuitive and ergonomic solutions for fluorescence image-guided surgery, aiming to enhance surgical precision in both human and veterinary medicine. OnLume is dedicated to providing surgeons with high-quality images in well-lit surgical environments. The company is currently testing prototypes in collaboration with the Laboratory for Optical and Computational Imaging (LOCI) and the Morgridge Institute for Research, both located in Madison. However, the systems have not yet received FDA clearance for market release and are not available for sale.
Stuart Therapeutics is a biotechnology company focused on developing PolyCol, a therapeutic platform designed for various ophthalmic conditions. This innovative platform utilizes a synthesized peptide to repair disease-damaged helical collagen in the eye, promoting accelerated healing of epithelial cells, restoring nerve function, and reducing inflammation. PolyCol addresses several ophthalmic indications, including dry eye disease, dry age-related macular degeneration, and glaucoma. The technology is rooted in patented research from a prominent U.S. university and is supported by additional intellectual property acquired by the company. In addition to ophthalmic applications, Stuart Therapeutics is exploring the use of PolyCol for gastrointestinal, inflammatory, and oncology conditions, aiming to provide new treatment options across a range of medical fields.
LÜM is a Madison-based startup that has developed a streaming music platform and social network aimed at supporting emerging artists. The platform enables fans to discover, share, and directly support up-and-coming musicians from around the world. By focusing on local talent, LÜM seeks to bridge the gap in exposure between established artists and new music, fostering a community that promotes undiscovered sounds. The application reimagines the intersection of social media and music streaming, positioning itself as a talent pool for live entertainment. Through its innovative approach, LÜM allows artists to monetize their work and engage with fans throughout their careers, ultimately contributing to a more equitable music landscape.
LÜM is a Madison-based startup that has developed a streaming music platform and social network aimed at supporting emerging artists. The platform enables fans to discover, share, and directly support up-and-coming musicians from around the world. By focusing on local talent, LÜM seeks to bridge the gap in exposure between established artists and new music, fostering a community that promotes undiscovered sounds. The application reimagines the intersection of social media and music streaming, positioning itself as a talent pool for live entertainment. Through its innovative approach, LÜM allows artists to monetize their work and engage with fans throughout their careers, ultimately contributing to a more equitable music landscape.
At PROMISS Diagnostics they take applied science seriously. We believe marrying basic science with cutting-edge analytics can unleash exponential diagnostic potential from otherwise common blood tests. Their team is passionate about driving change and helping more people find hope by developing innovative diagnostic tools that are efficacious, inexpensive, and accessible to all.
SimpleMachines, Inc. is a semiconductor design and development company based in Madison, Wisconsin, established in 2016. It specializes in creating a Software-Defined Compute platform that addresses the evolving demands of artificial intelligence, virtual reality, machine learning, robotics, and big data. As traditional computing systems face limitations due to the end of Moore's Law and the increasing complexity of software, SimpleMachines offers a programmable platform that allows for real-time hardware optimization. This innovative approach contrasts with conventional single-purpose systems, which are costly, time-consuming to develop, and often become obsolete upon deployment. The company's platform enables software developers to enhance application performance by dynamically reconfiguring hardware, thus supporting a wide range of use cases and ensuring adaptability in rapidly changing technological environments.
HealthMyne, Inc. is a healthcare informatics company based in Madison, Wisconsin, established in 2013. It specializes in providing innovative search, analytics, and imaging solutions primarily for cancer care providers. The company's smart imaging technology supports clinical decision-making by offering real-time, evidence-based insights that enhance diagnostic accuracy and foster collaboration among healthcare professionals. HealthMyne's platform includes features such as automatic tumor staging, dose overlays, specialized reporting, and management of incidental findings, all aimed at improving patient care and optimizing the efficiency of clinical workflows. By integrating electronic health record capabilities with advanced imaging solutions, HealthMyne seeks to reduce care delivery costs while ensuring that clinicians have access to relevant patient information for informed treatment decisions.
SimpleMachines, Inc. is a semiconductor design and development company based in Madison, Wisconsin, established in 2016. It specializes in creating a Software-Defined Compute platform that addresses the evolving demands of artificial intelligence, virtual reality, machine learning, robotics, and big data. As traditional computing systems face limitations due to the end of Moore's Law and the increasing complexity of software, SimpleMachines offers a programmable platform that allows for real-time hardware optimization. This innovative approach contrasts with conventional single-purpose systems, which are costly, time-consuming to develop, and often become obsolete upon deployment. The company's platform enables software developers to enhance application performance by dynamically reconfiguring hardware, thus supporting a wide range of use cases and ensuring adaptability in rapidly changing technological environments.
FluGen, Inc. is a biopharmaceutical company focused on developing vaccines to prevent diseases caused by influenza viruses. Founded in 2007 and based in Madison, Wisconsin, FluGen offers RedeeFlu, a nasal spray vaccine designed to protect against influenza, along with a vaccine-loaded intradermal microneedle delivery device. The company aims to address both seasonal and pandemic influenza on a global scale.
Isomark, LLC is a company based in Madison, Wisconsin, established in 2005, that specializes in non-invasive breath monitoring technology aimed at detecting life-threatening infections. Its primary product, Canary, functions as a breath analyzer that measures and analyzes isotopic biomarkers present in exhaled CO2 samples. This technology enables healthcare providers to monitor personal health and identify disease states effectively. Isomark's approach facilitates the early detection and treatment of infections, including hospital-related conditions like sepsis, thereby allowing for timely medical intervention before illnesses progress to more serious or chronic stages. The company's solutions are applicable in various clinical settings, including primary disease detection and outpatient medical services, as well as post-operative patient monitoring.
HealthMyne, Inc. is a healthcare informatics company based in Madison, Wisconsin, established in 2013. It specializes in providing innovative search, analytics, and imaging solutions primarily for cancer care providers. The company's smart imaging technology supports clinical decision-making by offering real-time, evidence-based insights that enhance diagnostic accuracy and foster collaboration among healthcare professionals. HealthMyne's platform includes features such as automatic tumor staging, dose overlays, specialized reporting, and management of incidental findings, all aimed at improving patient care and optimizing the efficiency of clinical workflows. By integrating electronic health record capabilities with advanced imaging solutions, HealthMyne seeks to reduce care delivery costs while ensuring that clinicians have access to relevant patient information for informed treatment decisions.
FluGen, Inc. is a biopharmaceutical company focused on developing vaccines to prevent diseases caused by influenza viruses. Founded in 2007 and based in Madison, Wisconsin, FluGen offers RedeeFlu, a nasal spray vaccine designed to protect against influenza, along with a vaccine-loaded intradermal microneedle delivery device. The company aims to address both seasonal and pandemic influenza on a global scale.
Isomark, LLC is a company based in Madison, Wisconsin, established in 2005, that specializes in non-invasive breath monitoring technology aimed at detecting life-threatening infections. Its primary product, Canary, functions as a breath analyzer that measures and analyzes isotopic biomarkers present in exhaled CO2 samples. This technology enables healthcare providers to monitor personal health and identify disease states effectively. Isomark's approach facilitates the early detection and treatment of infections, including hospital-related conditions like sepsis, thereby allowing for timely medical intervention before illnesses progress to more serious or chronic stages. The company's solutions are applicable in various clinical settings, including primary disease detection and outpatient medical services, as well as post-operative patient monitoring.
Isomark, LLC is a company based in Madison, Wisconsin, established in 2005, that specializes in non-invasive breath monitoring technology aimed at detecting life-threatening infections. Its primary product, Canary, functions as a breath analyzer that measures and analyzes isotopic biomarkers present in exhaled CO2 samples. This technology enables healthcare providers to monitor personal health and identify disease states effectively. Isomark's approach facilitates the early detection and treatment of infections, including hospital-related conditions like sepsis, thereby allowing for timely medical intervention before illnesses progress to more serious or chronic stages. The company's solutions are applicable in various clinical settings, including primary disease detection and outpatient medical services, as well as post-operative patient monitoring.
Holos, Inc. is an educational technology company that specializes in augmented and virtual reality solutions. Founded in 2015 and based in Madison, Wisconsin, Holos offers a spatial computing platform that allows teachers and students to create, organize, and engage with content in immersive 3D environments. This platform functions similarly to a 3D version of PowerPoint, enabling users to incorporate various media such as photos, videos, text, and 3D models into their virtual spaces. Holos provides tools such as collaborative presentation features and a content library filled with pre-vetted 3D learning experiences. Its technology is designed to facilitate intuitive interaction through natural inputs, making it suitable for advanced training, education, and enterprise applications.
StudyBlue is a mobile learning platform designed to help students learn the stuff their teachers teach from improving outcomes in and out of the classroom. StudyBlue provides a Digital Backpack for students to store, study, share, compare, and ultimately master course material – working alone or together. Notes with images and audio, cloud storage for notes, personalized practice quizzes, and crowdsourced study guides are among the tools offered.
FluGen, Inc. is a biopharmaceutical company focused on developing vaccines to prevent diseases caused by influenza viruses. Founded in 2007 and based in Madison, Wisconsin, FluGen offers RedeeFlu, a nasal spray vaccine designed to protect against influenza, along with a vaccine-loaded intradermal microneedle delivery device. The company aims to address both seasonal and pandemic influenza on a global scale.
Madison Vaccines, Inc. is a biopharmaceutical company based in Madison, Wisconsin, focused on developing therapeutic plasmid DNA vaccines for prostate cancer and its associated bone metastases. Founded by Douglas McNeel, M.D., Ph.D., and Richard Lesniewski, Ph.D., the company is working on two primary vaccines: pTVG-HP and pTVG-AR. The lead vaccine, pTVG-HP, is administered via intradermal injection and targets prostatic acid phosphatase (PAP), with ongoing Phase 2 clinical trials for men at high risk of developing bone metastases following prostate cancer treatment. Initial trials have shown promising biological and biochemical activity. The second vaccine, pTVG-AR, aims to target the androgen receptor, a key driver of prostate cancer growth, and is expected to enter clinical trials soon. Additionally, Madison Vaccines is developing a companion diagnostic test based on a novel blood signature identified by the McNeel lab, which could help predict patient responses to these vaccines.
StudyBlue is a mobile learning platform designed to help students learn the stuff their teachers teach from improving outcomes in and out of the classroom. StudyBlue provides a Digital Backpack for students to store, study, share, compare, and ultimately master course material – working alone or together. Notes with images and audio, cloud storage for notes, personalized practice quizzes, and crowdsourced study guides are among the tools offered.
Isomark, LLC is a company based in Madison, Wisconsin, established in 2005, that specializes in non-invasive breath monitoring technology aimed at detecting life-threatening infections. Its primary product, Canary, functions as a breath analyzer that measures and analyzes isotopic biomarkers present in exhaled CO2 samples. This technology enables healthcare providers to monitor personal health and identify disease states effectively. Isomark's approach facilitates the early detection and treatment of infections, including hospital-related conditions like sepsis, thereby allowing for timely medical intervention before illnesses progress to more serious or chronic stages. The company's solutions are applicable in various clinical settings, including primary disease detection and outpatient medical services, as well as post-operative patient monitoring.
Madison Vaccines, Inc. is a biopharmaceutical company based in Madison, Wisconsin, focused on developing therapeutic plasmid DNA vaccines for prostate cancer and its associated bone metastases. Founded by Douglas McNeel, M.D., Ph.D., and Richard Lesniewski, Ph.D., the company is working on two primary vaccines: pTVG-HP and pTVG-AR. The lead vaccine, pTVG-HP, is administered via intradermal injection and targets prostatic acid phosphatase (PAP), with ongoing Phase 2 clinical trials for men at high risk of developing bone metastases following prostate cancer treatment. Initial trials have shown promising biological and biochemical activity. The second vaccine, pTVG-AR, aims to target the androgen receptor, a key driver of prostate cancer growth, and is expected to enter clinical trials soon. Additionally, Madison Vaccines is developing a companion diagnostic test based on a novel blood signature identified by the McNeel lab, which could help predict patient responses to these vaccines.
Silatronix, Inc. is a company based in Madison, Wisconsin, specializing in the development of organosilicon (OS) compounds and formulations for energy storage applications. Founded in 2007, the company focuses on creating organosilicon electrolytes used in both rechargeable and non-rechargeable lithium-ion batteries, as well as in ultracapacitors. Silatronix combines expert knowledge in organosilicon chemistry with advancements in nanostructured electrodes and the electronic properties of materials, aimed at enhancing the performance and efficiency of energy storage devices. Its innovative products are integral to the evolving landscape of energy storage technology.
NeuWave Medical develops tools that deliver energy to the human body to treat a variety of serious medical conditions. Their company founders are both engineers and physician-scientists which allows determining a clinical need and design solutions that are clinically relevant, effective, and minimally invasive. They strive to make the highest quality devices that are the products of choice for leading physicians and medical centers around the world. The company was founded in 2004 and is headquartered in Madison, Wisconsin.
Cellular Dynamics International Inc., (CDI) is a developer and manufacturer of fully functioning cells in industrial quantities to precise specifications. CDI's proprietary products include true human cells in multiple cell types (iCell products), human induced pluripotent stem cells (iPSCs) and custom iPSCs and iCell products (MyCell Products). CDI's products provide standardized, easy-to-use, cost-effective access to the human cell, the smallest fully functioning operating unit of human biology. Customers use our products, among other purposes, for drug discovery and screening, to test the safety and efficacy of their small molecule and biological drug candidates, for stem cell banking, and in the research and development of cellular therapeutics.
NeuWave Medical develops tools that deliver energy to the human body to treat a variety of serious medical conditions. Their company founders are both engineers and physician-scientists which allows determining a clinical need and design solutions that are clinically relevant, effective, and minimally invasive. They strive to make the highest quality devices that are the products of choice for leading physicians and medical centers around the world. The company was founded in 2004 and is headquartered in Madison, Wisconsin.
Deltanoid Pharmaceuticals is a biopharmaceutical company based in Madison, Wisconsin, focused on the research, development, and commercialization of therapies for various human diseases, including renal diseases, osteoporosis, and skin conditions. Founded in 1999, the company initially aimed to advance university inventions, particularly vitamin D analogs and other compounds licensed from the Wisconsin Alumni Research Foundation. Deltanoid's notable products include DP001, which targets secondary hyperparathyroidism in patients with chronic kidney disease undergoing hemodialysis, and DP006 for acne treatment. The company is dedicated to developing selected therapies through the early phases of drug development and actively seeks partnerships for later-stage development and commercialization. Currently, Deltanoid has a partnership with Novadiol, Inc. for the development of a vitamin D therapy.
Mithridion, Inc. is a biopharmaceutical company based in Madison, Wisconsin, focused on discovering and developing small molecule drugs to address unmet medical needs, particularly in the area of central nervous system disorders. The company targets serious chronic neurodegenerative diseases, including orphan diseases and schizophrenia. Its drug portfolio includes MCD-386CR, aimed at treating cognitive impairments associated with Progressive Supranuclear Palsy and other neurodegenerative conditions; MCD-386/glycopyrrolate, designed as a preventative therapy for genetically-defined presymptomatic mutation carriers of autosomal dominant Alzheimer’s disease; MI-08-016/035, which are candidates for common neurodegenerative diseases; and MI-10-022, targeting significant unmet needs in schizophrenia. Founded in 2004, Mithridion aims to provide innovative therapeutic solutions for complex neurological conditions.
OpGen, Inc. is a precision medicine company based in Gaithersburg, Maryland, that specializes in developing molecular diagnostics and informatics aimed at combating infectious diseases. The company offers a range of products, including the Acuitas AMR Gene Panel, which detects bacterial nucleic acids and antimicrobial resistance markers, and QuickFISH and PNA FISH tests for identifying pathogens in blood cultures. Additionally, OpGen provides the Acuitas Lighthouse informatics system, a cloud-based platform that integrates clinical lab results with patient data to help manage multidrug-resistant organisms in healthcare settings. Through its strategic collaboration with the New York State Department of Health, OpGen is working on solutions to detect and manage antimicrobial-resistant infections in healthcare facilities. The company's innovative technologies are utilized by academic, government, and research institutions globally for applications such as strain typing and genome assembly. OpGen aims to enhance patient care and outcomes while addressing the growing challenge of antibiotic resistance.
Roche NimbleGen specializes in providing a range of products and services for the life science research market, particularly in DNA sequencing and microarray technology. The company offers the SeqCap EZ system, which allows for exome enrichment in a single test tube, along with various design options and reagents to facilitate workflow. Additionally, Roche NimbleGen has developed the SeqCap Epi system for DNA methylation assessment at single-base resolution, and it supplies preparation and adapter kits for library construction. Their proprietary Maskless Array Synthesis technology enables the creation of custom high-density DNA arrays, enhancing the quality and data yield of sequencing efforts. The company also provides a suite of DNA microarray products for applications such as comparative genomic hybridization and gene expression analysis, alongside technical support services. Founded in 1999 and based in Madison, Wisconsin, Roche NimbleGen operates as a subsidiary of Roche Holding AG.
Roche NimbleGen specializes in providing a range of products and services for the life science research market, particularly in DNA sequencing and microarray technology. The company offers the SeqCap EZ system, which allows for exome enrichment in a single test tube, along with various design options and reagents to facilitate workflow. Additionally, Roche NimbleGen has developed the SeqCap Epi system for DNA methylation assessment at single-base resolution, and it supplies preparation and adapter kits for library construction. Their proprietary Maskless Array Synthesis technology enables the creation of custom high-density DNA arrays, enhancing the quality and data yield of sequencing efforts. The company also provides a suite of DNA microarray products for applications such as comparative genomic hybridization and gene expression analysis, alongside technical support services. Founded in 1999 and based in Madison, Wisconsin, Roche NimbleGen operates as a subsidiary of Roche Holding AG.