HistoSonics provides the Edison Platform, which uses advanced imaging and proprietary sensing technology to deliver non-invasive, personalized treatments with precision and control, and uses the science of histotripsy and focused sound energy to generate pressures to liquify and completely destroy targeted tissues at sub-cellular levels.
OnShift provides cloud-based human capital management software and proactive services tailored for the healthcare sector, specifically focusing on post-acute and long-term care facilities. The company's platform addresses workforce challenges by offering solutions for hiring, scheduling, employee engagement, and talent acquisition. With features such as workforce analytics and customer success management, OnShift empowers organizations to enhance productivity and profitability while ensuring consistent staffing and quality care. Its intuitive design and use of predictive analytics have made it a trusted choice for numerous senior living and post-acute care organizations seeking to optimize their workforce management.
Amplifinity, LLC specializes in developing and providing referral software designed for Fortune 500 companies and advocates. The company's Advocate Management Platform (AMP) equips organizations with tools to implement word-of-mouth marketing campaigns efficiently. Key features of AMP include the Program Builder, which allows users to design, launch, and analyze various advocacy campaigns, and the Advocate Database, which maintains individual profiles for advocates. Amplifinity's platform automates the tracking and management of customer and partner referrals, ensuring streamlined reward fulfillment and incentive structures. It serves diverse sectors such as travel, entertainment, financial services, and home goods. Established in 2007 and based in Ann Arbor, Michigan, Amplifinity operates as a subsidiary of Impartner Software, Inc. Notable clients include ADP, LogMeIn, and Citrix.
OnShift provides cloud-based human capital management software and proactive services tailored for the healthcare sector, specifically focusing on post-acute and long-term care facilities. The company's platform addresses workforce challenges by offering solutions for hiring, scheduling, employee engagement, and talent acquisition. With features such as workforce analytics and customer success management, OnShift empowers organizations to enhance productivity and profitability while ensuring consistent staffing and quality care. Its intuitive design and use of predictive analytics have made it a trusted choice for numerous senior living and post-acute care organizations seeking to optimize their workforce management.
CardioX is a company that specializes in developing advanced systems for measuring and monitoring various cardiovascular health parameters, including cardiac output, total circulating blood volume, and endogenous blood ammonia levels. Founded in 1996 and based in Columbus, Ohio, CardioX has expanded its offerings to include a mobile application for tracking and recording electrocardiograms (ECG). This app leverages a vast dataset from clinical records to enhance its machine learning algorithms, enabling the detection of abnormalities in cardiac patterns. Notably, CardioX has achieved a breakthrough in real-time blood pressure monitoring, providing users with accurate on-the-fly readings. The company is actively working on integrating data from third-party activity trackers and enhancing its artificial intelligence capabilities, which will allow users to interpret ECG graphs through simple image uploads. CardioX aims to harness these advancements to improve heart health management and expand the range of vital health parameters that can be monitored through its technology.
Juventas Therapeutics, Inc., a clinical stage biotechnology company, develops non-viral gene therapies that activate natural processes to repair the body. The company focuses on treatment of non-healing wounds in patients with advanced peripheral artery disease. It offers JVS-100, a non-viral gene therapy that expresses stromal cell-derived factor-1 or SDF-1, a naturally occurring signaling protein that has been shown to recruit the body’s own stem cells and promote tissue repair in a range of disease states. Juventas Therapeutics, Inc. was formerly known as AcelleRX Therapeutics, Inc. and changed its name to Juventas Therapeutics, Inc. in April 2009. The company was founded in 2007 and is based in Cleveland, Ohio.
OnShift provides cloud-based human capital management software and proactive services tailored for the healthcare sector, specifically focusing on post-acute and long-term care facilities. The company's platform addresses workforce challenges by offering solutions for hiring, scheduling, employee engagement, and talent acquisition. With features such as workforce analytics and customer success management, OnShift empowers organizations to enhance productivity and profitability while ensuring consistent staffing and quality care. Its intuitive design and use of predictive analytics have made it a trusted choice for numerous senior living and post-acute care organizations seeking to optimize their workforce management.
LineStream Technologies, Inc. specializes in developing control technology and software solutions aimed at enhancing the performance of automated products and processes. Founded in 2006 and based in Cleveland, Ohio, the company provides embedded software that integrates into a variety of applications, from household appliances like washing machines to advanced manufacturing equipment. LineStream's software is designed to actively reject process disturbances, thereby mitigating potential degradation of system performance. This capability allows businesses to achieve improved efficiency while simplifying control and tuning processes. Formerly known as ADRC Technologies, Inc., the company rebranded in March 2010 to better reflect its focus on innovative control technologies.
CytoPherx (formerly Nephrion) clinical stage medical device company addressing inflammation-based diseases and conditions. The company’s products are custom configurations of a proprietary selective cytopheresis-based inflammation modulating system.
Amplifinity, LLC specializes in developing and providing referral software designed for Fortune 500 companies and advocates. The company's Advocate Management Platform (AMP) equips organizations with tools to implement word-of-mouth marketing campaigns efficiently. Key features of AMP include the Program Builder, which allows users to design, launch, and analyze various advocacy campaigns, and the Advocate Database, which maintains individual profiles for advocates. Amplifinity's platform automates the tracking and management of customer and partner referrals, ensuring streamlined reward fulfillment and incentive structures. It serves diverse sectors such as travel, entertainment, financial services, and home goods. Established in 2007 and based in Ann Arbor, Michigan, Amplifinity operates as a subsidiary of Impartner Software, Inc. Notable clients include ADP, LogMeIn, and Citrix.
CardioX is a company that specializes in developing advanced systems for measuring and monitoring various cardiovascular health parameters, including cardiac output, total circulating blood volume, and endogenous blood ammonia levels. Founded in 1996 and based in Columbus, Ohio, CardioX has expanded its offerings to include a mobile application for tracking and recording electrocardiograms (ECG). This app leverages a vast dataset from clinical records to enhance its machine learning algorithms, enabling the detection of abnormalities in cardiac patterns. Notably, CardioX has achieved a breakthrough in real-time blood pressure monitoring, providing users with accurate on-the-fly readings. The company is actively working on integrating data from third-party activity trackers and enhancing its artificial intelligence capabilities, which will allow users to interpret ECG graphs through simple image uploads. CardioX aims to harness these advancements to improve heart health management and expand the range of vital health parameters that can be monitored through its technology.
SironRX is developing novel therapies exclusively licensed from Juventas Therapeutics and Cleveland Clinic that promote dermal wound repair and reduce scarring. Our lead product is a clinically tested biopharmaceutical that encodes Stromal cell-Derived Factor-1 (SDF-1). SDF-1 is key molecule responsible for activating natural repair processes after tissue injury through prevention of cell death and recruitment of stem cells to the damaged organ. Studies from several laboratories suggest the therapeutic potential of SDF-1 for treatment of a range of wounds such as post-surgical incisions, chronic diabetic ulcers and burns. Development of a cost-effective interactive wound therapy that can be topically administered at the site-of-injury or in chronic wound care settings with the potential to significantly improve function of the damaged tissue will have a major impact on the multi-billion dollar advanced wound management market.
TOA Technologies specializes in field service management software designed for businesses that operate in the field. Their flagship product, ETAdirect, is a cloud-based solution that utilizes a patented time-based predictive analytics platform. ETAdirect analyzes how work is performed by individual employees, identifies patterns, and predicts the most efficient routes based on real-time data. This system communicates updates to consumers throughout the service process, enhancing transparency and engagement. By implementing ETAdirect, TOA's clients can improve the effectiveness of their field service teams, leading to reduced customer wait times and increased productivity in service operations.
OnShift provides cloud-based human capital management software and proactive services tailored for the healthcare sector, specifically focusing on post-acute and long-term care facilities. The company's platform addresses workforce challenges by offering solutions for hiring, scheduling, employee engagement, and talent acquisition. With features such as workforce analytics and customer success management, OnShift empowers organizations to enhance productivity and profitability while ensuring consistent staffing and quality care. Its intuitive design and use of predictive analytics have made it a trusted choice for numerous senior living and post-acute care organizations seeking to optimize their workforce management.
AxioMed LLC, founded in 2001 and located in Malden, Massachusetts, specializes in designing and developing disc replacement devices aimed at alleviating neck pain and restoring normal spinal functions for patients suffering from degenerative disc disease. The company, previously known as AxioMed Spine Corporation until its name change in 2014, has focused on advancing the standard of care beyond traditional fusion and first-generation artificial discs. AxioMed has developed the Freedom® Lumbar Disc and is currently working on a project for cervical spine applications, having initiated clinical trials for its products. The management team, led by CEO Patrick McBrayer and COO James Kuras, consists of experienced professionals with significant expertise in spinal implants. Additionally, AxioMed collaborates with a Medical Advisory Panel of surgeons from prominent spine centers and universities to enhance its product development and regulatory strategies.
Prevacept Infection Control is a clinical-stage company focused on developing and commercializing products that prevent infections associated with indwelling catheters.
Intelligent Clearing Network, Inc. is a software-as-a-service company that specializes in the electronic validation and clearing of paper and digital coupons, as well as other incentives, for grocery, drug, and mass merchant retailers. Founded in 2008 and based in Connecticut, the company provides a fully automated promotion management system that allows retailers to maintain control over their promotions while significantly reducing the risk of fraud. Its services include promotion management, coupon validation, fraud protection, and direct-to-card offers. By facilitating real-time validation at the point-of-sale, Intelligent Clearing Network addresses issues related to misredemption and fraudulent coupon use, delivering real-time redemption information to manufacturers, media companies, and retailers when incentives are processed.
Reverse Medical is a commercial-stage medical device company focused on revascularizing patients experiencing Acute Ischemic Stroke.
HistoSonics provides the Edison Platform, which uses advanced imaging and proprietary sensing technology to deliver non-invasive, personalized treatments with precision and control, and uses the science of histotripsy and focused sound energy to generate pressures to liquify and completely destroy targeted tissues at sub-cellular levels.
Simbionix USA Corporation specializes in simulation, training, and education solutions for medical professionals and the healthcare industry. Founded in 1997 and based in Cleveland, Ohio, with a research and development center in Israel, the company offers a range of training simulators, including those for laparoscopic, endovascular, endoscopic, and bronchoscopy procedures. Its innovative tools include the Simbionix Learning Management System, which tracks and reports learner performance, and the PROcedure Rehearsal Studio, enabling clinicians to create patient-specific 3D virtual anatomical models from CT scans. Simbionix distributes its products across various regions, including the Middle East, South America, Asia-Pacific, and Europe, serving a diverse clientele of surgeons, interventionists, nurses, and technicians. The company is dedicated to enhancing clinical performance and improving procedural outcomes through advanced training solutions.
Juventas Therapeutics, Inc., a clinical stage biotechnology company, develops non-viral gene therapies that activate natural processes to repair the body. The company focuses on treatment of non-healing wounds in patients with advanced peripheral artery disease. It offers JVS-100, a non-viral gene therapy that expresses stromal cell-derived factor-1 or SDF-1, a naturally occurring signaling protein that has been shown to recruit the body’s own stem cells and promote tissue repair in a range of disease states. Juventas Therapeutics, Inc. was formerly known as AcelleRX Therapeutics, Inc. and changed its name to Juventas Therapeutics, Inc. in April 2009. The company was founded in 2007 and is based in Cleveland, Ohio.
Arisdyne Systems, Inc. specializes in developing advanced process improvement equipment, focusing on high shear force, high temperature, and hydrodynamic cavitation technologies. The company offers solutions that enhance yields in various applications, including ethanol production from starch and fiber, vegetable oil degumming, and wastewater treatment. Arisdyne's patented controlled flow cavitation process generates energy peaks to efficiently reduce particle size, disrupt cell structures, and accelerate chemical reactions. Their small footprint devices are designed for easy integration and scalability from laboratory to industrial environments. Founded in 2006 and based in Cleveland, Ohio, Arisdyne operates as a subsidiary of Five Star Technologies, Inc.
EcoSMART Technologies, Inc. specializes in the manufacture of pesticide solutions and pet care products derived from natural ingredients. Founded in 1992 and headquartered in Atlanta, Georgia, the company offers a comprehensive range of pest control products, including insecticides for ants, roaches, bed bugs, fleas, ticks, mosquitoes, and various garden pests. EcoSMART's products are unique in that they utilize essential plant oils, leveraging natural defenses that plants have developed over millennia to combat insects and pathogens. The company emphasizes safety, providing a complete line of EPA-exempt pesticides that are effective without the use of synthetic chemicals or harmful residues. EcoSMART also markets pet care items such as shampoos, conditioners, and flea and tick control products. These offerings are available through online platforms and retail stores, catering to both residential and commercial markets. As a subsidiary of Kittrich Corporation, EcoSMART strives to lead the industry in safe and effective pesticide solutions.
LineStream Technologies, Inc. specializes in developing control technology and software solutions aimed at enhancing the performance of automated products and processes. Founded in 2006 and based in Cleveland, Ohio, the company provides embedded software that integrates into a variety of applications, from household appliances like washing machines to advanced manufacturing equipment. LineStream's software is designed to actively reject process disturbances, thereby mitigating potential degradation of system performance. This capability allows businesses to achieve improved efficiency while simplifying control and tuning processes. Formerly known as ADRC Technologies, Inc., the company rebranded in March 2010 to better reflect its focus on innovative control technologies.
Imalux Corporation, an Ohio medical device company, is positioned to become the worldwide leader in the commercializationPhoto of medical imaging equipment and devices based on its proprietary Optical Coherence Tomography (OCT) technology. The Company’s products provide real-time, high spatial resolution imaging at the point-of-care in a variety of medical applications. OCT is a new imaging modality for visualization of tissue microstructure, especially in anatomical areas with stratified tissue. It has the ability to detect near-surface tissue abnormalities indicative of disease, which established imaging modalities might not detect. Many diseases, including cancer, are associated with superficial tissue structure disruption. Today, there is no commercialized in vivo method to visualize this tissue structure alteration; clinicians must do a biopsy and an ex vivo histopathological review using a conventional microscope. Imalux OCT products can be used to visualize structural disruptions in vivo at the point of care.
Blue Spark Technologies develops power source solutions for battery-powered printed electronic systems. It also develops flexible, printed, "green," proprietary power source solutions for battery-powered printed electronic systems. The company was founded as Thin Battery Technologies in 2002 with patented technology and technical leadership from Energizer (Eveready Battery Company).
Blue Spark Technologies was founded in 2003 and headquartered in Westlake, Ohio.
Five Star Technologies is a supplier of high-performance dispersions, inks and pastes used in displays, photovoltaics, and microelectronic packaging. Combining its patented hydrodynamic cavitation process with innovative chemistry, Five Star produces the ElectroSperseâ„¢ series of inks and pastes as well as a wide range of precision dispersions. The ElectroSperse line features a range of conductive pastes with exceptional printability, low firing temperatures, high levels of conductivity, strong adhesion to a variety of substrates, and RoHS compliance. ElectroSperse grades can be tailored for a range of processing techniques, including screen, gravure, extrusion and ink jet printing. Targeted applications include electrodes, interconnects, and linearization patterns for displays, photovoltaic front side contacts, and hybrid microcircuits.
EcoSMART Technologies, Inc. specializes in the manufacture of pesticide solutions and pet care products derived from natural ingredients. Founded in 1992 and headquartered in Atlanta, Georgia, the company offers a comprehensive range of pest control products, including insecticides for ants, roaches, bed bugs, fleas, ticks, mosquitoes, and various garden pests. EcoSMART's products are unique in that they utilize essential plant oils, leveraging natural defenses that plants have developed over millennia to combat insects and pathogens. The company emphasizes safety, providing a complete line of EPA-exempt pesticides that are effective without the use of synthetic chemicals or harmful residues. EcoSMART also markets pet care items such as shampoos, conditioners, and flea and tick control products. These offerings are available through online platforms and retail stores, catering to both residential and commercial markets. As a subsidiary of Kittrich Corporation, EcoSMART strives to lead the industry in safe and effective pesticide solutions.
TetraLogic Pharmaceuticals is a privately held biopharmaceutical company focused on discovering and developing small molecule drugs aimed at treating serious diseases. The company specializes in therapies that modulate programmed cell death pathways. Its Smac Mimetics are designed to target and neutralize obstacles in the apoptosis pathway, enabling the selective destruction of cancer cells. Additionally, TetraLogic's Necrostatin drugs work by blocking key processes that lead to necrosis, promoting cell survival in various diseases and conditions where necrosis plays a significant role in the pathology. Through its innovative approach, TetraLogic aims to address critical unmet medical needs in oncology and beyond.
LogMeIn, Inc. offers a comprehensive suite of cloud-based solutions focused on communication, collaboration, identity management, and customer engagement. The company provides products such as GoToMeeting, a platform for online meetings; GoToWebinar, designed for webinars; and GoToTraining, for interactive training sessions. Additionally, it offers tools like LogMeIn Pro for remote access, LastPass for password management, and Bold360 for customer engagement. Other notable services include Jive, a cloud-based phone system, and Rescue, which provides remote support and customer care. LogMeIn serves a diverse range of clients, including enterprise customers, small and medium businesses, IT service providers, and consumers. Founded in 2003 and headquartered in Boston, Massachusetts, LogMeIn was taken private in 2020.
Unitask, Inc. develops and sells software solutions designed to automate tasks related to the Oracle E-Business Suite (EBS). Its key products include Unitask Output Director, which streamlines output management by automating printer configurations and enabling users to print, fax, email, and store reports; and Unitask Migration Director, which facilitates the automation of code migrations within Oracle EBS. Additionally, the Unitask Command Center provides a web-based interface for managing these automation solutions. The company's software serves a diverse range of industries such as oil and gas, manufacturing, engineering, healthcare, and government, among others. Unitask, founded in 1994 and headquartered in Bloomfield Hills, Michigan, also has operations in Israel and serves customers globally across North America, South America, Europe, Asia, Australia, and Africa.
TOA Technologies specializes in field service management software designed for businesses that operate in the field. Their flagship product, ETAdirect, is a cloud-based solution that utilizes a patented time-based predictive analytics platform. ETAdirect analyzes how work is performed by individual employees, identifies patterns, and predicts the most efficient routes based on real-time data. This system communicates updates to consumers throughout the service process, enhancing transparency and engagement. By implementing ETAdirect, TOA's clients can improve the effectiveness of their field service teams, leading to reduced customer wait times and increased productivity in service operations.
AxioMed LLC, founded in 2001 and located in Malden, Massachusetts, specializes in designing and developing disc replacement devices aimed at alleviating neck pain and restoring normal spinal functions for patients suffering from degenerative disc disease. The company, previously known as AxioMed Spine Corporation until its name change in 2014, has focused on advancing the standard of care beyond traditional fusion and first-generation artificial discs. AxioMed has developed the Freedom® Lumbar Disc and is currently working on a project for cervical spine applications, having initiated clinical trials for its products. The management team, led by CEO Patrick McBrayer and COO James Kuras, consists of experienced professionals with significant expertise in spinal implants. Additionally, AxioMed collaborates with a Medical Advisory Panel of surgeons from prominent spine centers and universities to enhance its product development and regulatory strategies.
Imalux Corporation, an Ohio medical device company, is positioned to become the worldwide leader in the commercializationPhoto of medical imaging equipment and devices based on its proprietary Optical Coherence Tomography (OCT) technology. The Company’s products provide real-time, high spatial resolution imaging at the point-of-care in a variety of medical applications. OCT is a new imaging modality for visualization of tissue microstructure, especially in anatomical areas with stratified tissue. It has the ability to detect near-surface tissue abnormalities indicative of disease, which established imaging modalities might not detect. Many diseases, including cancer, are associated with superficial tissue structure disruption. Today, there is no commercialized in vivo method to visualize this tissue structure alteration; clinicians must do a biopsy and an ex vivo histopathological review using a conventional microscope. Imalux OCT products can be used to visualize structural disruptions in vivo at the point of care.
TetraLogic Pharmaceuticals is a privately held biopharmaceutical company focused on discovering and developing small molecule drugs aimed at treating serious diseases. The company specializes in therapies that modulate programmed cell death pathways. Its Smac Mimetics are designed to target and neutralize obstacles in the apoptosis pathway, enabling the selective destruction of cancer cells. Additionally, TetraLogic's Necrostatin drugs work by blocking key processes that lead to necrosis, promoting cell survival in various diseases and conditions where necrosis plays a significant role in the pathology. Through its innovative approach, TetraLogic aims to address critical unmet medical needs in oncology and beyond.
Five Star Technologies is a supplier of high-performance dispersions, inks and pastes used in displays, photovoltaics, and microelectronic packaging. Combining its patented hydrodynamic cavitation process with innovative chemistry, Five Star produces the ElectroSperseâ„¢ series of inks and pastes as well as a wide range of precision dispersions. The ElectroSperse line features a range of conductive pastes with exceptional printability, low firing temperatures, high levels of conductivity, strong adhesion to a variety of substrates, and RoHS compliance. ElectroSperse grades can be tailored for a range of processing techniques, including screen, gravure, extrusion and ink jet printing. Targeted applications include electrodes, interconnects, and linearization patterns for displays, photovoltaic front side contacts, and hybrid microcircuits.
Imalux Corporation, an Ohio medical device company, is positioned to become the worldwide leader in the commercializationPhoto of medical imaging equipment and devices based on its proprietary Optical Coherence Tomography (OCT) technology. The Company’s products provide real-time, high spatial resolution imaging at the point-of-care in a variety of medical applications. OCT is a new imaging modality for visualization of tissue microstructure, especially in anatomical areas with stratified tissue. It has the ability to detect near-surface tissue abnormalities indicative of disease, which established imaging modalities might not detect. Many diseases, including cancer, are associated with superficial tissue structure disruption. Today, there is no commercialized in vivo method to visualize this tissue structure alteration; clinicians must do a biopsy and an ex vivo histopathological review using a conventional microscope. Imalux OCT products can be used to visualize structural disruptions in vivo at the point of care.
Netilla Networks specializes in providing secure remote access solutions for corporate networks through its Netilla Service Platform, which is recognized as a leading SSL VPN appliance. This platform allows organizations to offer secure access to any application, whether on Windows, UNIX/Linux, or mainframe systems, via standard web browsers. By integrating thin-client technology with SSL encryption, along with a robust authentication and policy framework, Netilla Networks enables rapid deployment and reduces network exposure. The system is designed to lower maintenance costs compared to traditional VPNs while ensuring a user-friendly experience.
AxioMed LLC, founded in 2001 and located in Malden, Massachusetts, specializes in designing and developing disc replacement devices aimed at alleviating neck pain and restoring normal spinal functions for patients suffering from degenerative disc disease. The company, previously known as AxioMed Spine Corporation until its name change in 2014, has focused on advancing the standard of care beyond traditional fusion and first-generation artificial discs. AxioMed has developed the Freedom® Lumbar Disc and is currently working on a project for cervical spine applications, having initiated clinical trials for its products. The management team, led by CEO Patrick McBrayer and COO James Kuras, consists of experienced professionals with significant expertise in spinal implants. Additionally, AxioMed collaborates with a Medical Advisory Panel of surgeons from prominent spine centers and universities to enhance its product development and regulatory strategies.
Netilla Networks specializes in providing secure remote access solutions for corporate networks through its Netilla Service Platform, which is recognized as a leading SSL VPN appliance. This platform allows organizations to offer secure access to any application, whether on Windows, UNIX/Linux, or mainframe systems, via standard web browsers. By integrating thin-client technology with SSL encryption, along with a robust authentication and policy framework, Netilla Networks enables rapid deployment and reduces network exposure. The system is designed to lower maintenance costs compared to traditional VPNs while ensuring a user-friendly experience.