Stephen Barnes

MD

Michael Bolton

Founder and MD

Dean Miller

MD

Paul Schmitt

MD

Q"

Qingsheng "Ching" Zhu

Partner

41 past transactions

iGrandparents.com

Series A in 2000
IGrandparents is a blog that focuses on enriching the grandparent/grandchild relationship.

ClickEquations

Venture Round in 2009
ClickEquations provides a powerful pay per click software platform that enables advertisers and agencies to manage large paid search campaigns more effectively and efficiently. ClickEquations combines access to Google, Yahoo!, and MSN campaigns in a single web interface with bid management, campaign editing and reporting features. An advanced Excel plug-in, ClickEquations Analyst, provides unprecedented analytics depth and flexibility as well customizable and sharable reports and dashboards.

MedCases

Series A in 2000
MedCases focuses on the development of medical e-learning solutions for the pharmaceutical and biotechnology industry. MedCases offers ADHD Point of Care CME Program that focuses on educating physicians on the diagnosis and treatment of attention-deficit hyperactivity disorder. MedCases was acquired by Indegene Lifesystems in November 2006. MedCases was founded in 1971 and is based in Princeton, New Jersey.

Renal Solutions

Series B in 2005
Renal Solutions is focused on the development of dialysis products and services. Renal Solutions was acquired by Fresenius Medical Care in November 2007. Renal Solutions was founded in 2000 and is based in Warrendale, Pennsylvania.

Magic Bean Stalk

Series A in 2000
MagicBeanStalk helps the startup community find information, conduct transactions, and communicate more easily, bringing greater efficiency, reduced costs and faster growth to startups everywhere. In just a few short months, you'll be able to sift through profiles of the fastest growing Internet and high-tech startups across the globe, connect with service providers, participate in online discussions with industry leaders and share valuable information about your startup experience.

LifeShield

Series C in 2007
LifeShield is the first national, professional grade and professionally monitored wireless security system that provides superior protection and the best value in home security. Other home security systems typically fall into two categories: cheap and ineffective or expensive and one-dimensional. Customers are fooled into thinking they are protected, but many burglars can actually defeat these cheap systems in under 30 seconds. And traditional alarm system companies charge thousands of dollars to put sensors on first floor windows and doors, and even more on bedroom windows and upstairs entry points. Most people simply can't afford what they really need. With LifeShield customers get better protection, reliability, and superior control compared to traditional analog-based security systems. Plus, LifeShield was one of the first to provide remote access to your home security system. With LifeShield, you have always been able to log into your system from anywhere in the world for free. Some of the other systems are finally able to offer you this same type of access, but you'll pay for it. They'll add an extra cost to your monthly monitoring payments. And with LifeShield you can access your system even more easily with apps for iPhone, Blackberry, and Android. Look for our iPod application launch coming in July. We make home protection easy and convenient. Specialties Home Security, Home Automation, Alarm Systems, Security System Installation, Home security systems

Cernostics, Inc.

Venture Round in 2016
Cernostics is a life science company developing new molecular diagnostic tests for the fight against cancer. Most current diagnostic approaches offer a limited view of cancer because they fail to evaluate the tumor as a system composed of multiple cell types, not merely tumor cells. Its patent-protected technology platform, TissueCypher, uniquely analyzes whole slide digital images with multiplexed fluorescence, providing greater information and accuracy than traditional subjective tissue diagnostics.

iJET International

Series B in 2001
iJET was the first to introduce intelligence to the travel industry, which was then primarily focused on getting people from one location to another – not on keeping them safe during their trips. iJET began offering services that protected the individual traveler in March 2001, first through travel agencies and then to corporate travel departments. September 11, 2001 changed the way corporations thought about travelers and by the end of the year, iJET was protecting employees from 20 corporations.

Doctor Quality

Series B in 2000
The mission of DoctorQuality.com is to help the healthcare community, purchasers, and consumers to benefit from the highest quality healthcare available. DoctorQuality.com is the world's first Quality Benefits Management company (QBM). As a QBM company, DoctorQuality.com is positioned to take advantage of the growing "business case" for quality in healthcare. The premise of quality benefits management is that selecting and improving clinical quality is in the best economic interests for all key stakeholders in the healthcare industry. With quality benefits management, the marketplace will reward those that pursue the "quality" strategy. In defining this new market of quality benefits management, DoctorQuality.com has been created as an Internet-based company focusing on the business case for quality and providing an integrated suite of products and services to measure, select, pay for, and improve the quality of care.

TOA Technologies

Series C in 2008
TOA Technologies provides field service management software for businesses that operate in the field. Natively delivered through the cloud and the only solution using a patented time-based predictive analytics platform, TOA's ETAdirect provides a new way to manage mobile field service operations. ETAdirect learns how work is done in the field according to each individual employee, creates patterns, and then predicts the most optimized routes available based on real-time, actual data communicating this information with consumers throughout the service process every step of the way. With ETAdirect's unique approach to field service management, TOA's customers are able to empower their field service teams to be more effective, resulting in reduced customer wait times and increased field service productivity.

Wine Access

Venture Round in 2000
Drink only the most extraordinary wines, hand selected by a Master of wine and Master sommelier. Each wine passes rigorous screening to ensure it meets world class standards, and the quality and provenance of the wine is controlled and guaranteed from the winery to your door.

Agile Therapeutics, Inc.

Series C in 2012
Agile Therapeutics, Inc., a specialty pharmaceutical company, engages in the development of women's healthcare products. It offers a low estrogen dose seven-day transdermal contraceptive patch system that delivers a combination of levonorgestrel and Ethinylestradiol. The company was founded in 1997 as Levotech, Inc. and changed its name to Agile Therapeutics, Inc. in April 2001. It is based in Princeton, New Jersey.

Ventaira Pharmaceuticals

Series C in 2005
Ventaira Pharmaceuticals is an emerging specialty pharmaceutical company focused on the development of new inhalation products by utilizing its novel proprietary electrohydrodynamic (EHD) aerosolization and formulation technologies.

Logical Therapeutics

Series B in 2007
Logical Therapeutics, Inc., a biopharmaceutical company, engages in the development of drugs to treat diseases caused by or associated with excessive inflammation. Its products include LT-NS001, a non-steroidal anti-inflammatory drug for the treatment of chronic inflammatory conditions, such as osteoarthritis; Leptin, a hormone for the regulation of normal body mass and metabolism; and TNF, a hormone that promotes the proliferation of hepatocytes. The company was founded in 2005 and is based in Waltham, Massachusetts.

Gazelle Systems

Series B in 2000
Gazelle Systems is defining the value of technology in the hospitality industry by bringing valuable information about customers to the front of the house and at the point of sale. The Gazelle team brings decades of hands-on experience to its mission and is skilled in all facets of the restaurant business - from operations and IT, to marketing and management.

Half.com

Venture Round in 2000
Half.com is a person-to-person online marketplace that was acquired by [eBay](http://www.crunchbase.com/organization/ebay) in June 2000. Half.com was founded in 1999 by American entrepreneur Josh Kopelman (Infonautics, Turntide, Comcast Interactive Capital, First Round Capital) and Sunny Balijepalli (who more recently founded ZoomIn.com).[2] As an advertising gimmick, in December of the same year, the company paid the town of Halfway, Oregon US$100,000 and donated 20 new computers to change its name to "Half.com, Oregon" for a year.

Logical Therapeutics

Series C in 2010
Logical Therapeutics, Inc., a biopharmaceutical company, engages in the development of drugs to treat diseases caused by or associated with excessive inflammation. Its products include LT-NS001, a non-steroidal anti-inflammatory drug for the treatment of chronic inflammatory conditions, such as osteoarthritis; Leptin, a hormone for the regulation of normal body mass and metabolism; and TNF, a hormone that promotes the proliferation of hepatocytes. The company was founded in 2005 and is based in Waltham, Massachusetts.

EZ Prints

Venture Round in 2000
ezprints, Inc. operates as a private-label digital imaging solutions company. Its products include custom photo products like photo mugs greeting cards, personal photo creations, frames and albums, calendars, sports products, and digital products. The company serves consumer, retail, digital content, professional, and real estate verticals in the United States and Europe. ezprints, Inc. was founded in 1998 and is based in Norcross, Georgia.

Investor Broadcast Network

Venture Round in 2000
Investor Broadcast Network are Internet broadcaster of real-time investment information and analysis.

Cernostics, Inc.

Series B in 2013
Cernostics is a life science company developing new molecular diagnostic tests for the fight against cancer. Most current diagnostic approaches offer a limited view of cancer because they fail to evaluate the tumor as a system composed of multiple cell types, not merely tumor cells. Its patent-protected technology platform, TissueCypher, uniquely analyzes whole slide digital images with multiplexed fluorescence, providing greater information and accuracy than traditional subjective tissue diagnostics.

EZ Prints

Venture Round in 2002
ezprints, Inc. operates as a private-label digital imaging solutions company. Its products include custom photo products like photo mugs greeting cards, personal photo creations, frames and albums, calendars, sports products, and digital products. The company serves consumer, retail, digital content, professional, and real estate verticals in the United States and Europe. ezprints, Inc. was founded in 1998 and is based in Norcross, Georgia.
TetraLogic Pharmaceuticals is a privately held biopharmaceutical company that discovers and develops small molecule drugs that modulate programmed cell death pathways to treat debilitating diseases and conditions. The company's Smac Mimetics neutralize critical blocks in the apoptosis pathway to selectively destroy cancer cells. Its Necrostatin drugs block critical steps in the process leading to necrosis, enabling cell survival in a wide range of diseases and injuries where necrosis is a critical component of pathology.

Cellumen

Series B in 2007
Cellumen is the innovator in cellular systems biology (CSB™) solutions providing the most accurate predictions of drug efficacy and safety, thus reducing failure rates and cutting development costs. Cellumen’s CSB solutions are driving Discovery Toxicology by addressing the full complexity of disease and safety. Leading global organizations, such as the Mayo Clinic, Hamamatsu Photonics K.K., the EPA, FDA, NIH and top pharmaceutical companies, partner with Cellumen. Cellumen is a partner company of Safeguard Scientifics.
TetraLogic Pharmaceuticals is a privately held biopharmaceutical company that discovers and develops small molecule drugs that modulate programmed cell death pathways to treat debilitating diseases and conditions. The company's Smac Mimetics neutralize critical blocks in the apoptosis pathway to selectively destroy cancer cells. Its Necrostatin drugs block critical steps in the process leading to necrosis, enabling cell survival in a wide range of diseases and injuries where necrosis is a critical component of pathology.

Agile Therapeutics, Inc.

Series B in 2010
Agile Therapeutics, Inc., a specialty pharmaceutical company, engages in the development of women's healthcare products. It offers a low estrogen dose seven-day transdermal contraceptive patch system that delivers a combination of levonorgestrel and Ethinylestradiol. The company was founded in 1997 as Levotech, Inc. and changed its name to Agile Therapeutics, Inc. in April 2001. It is based in Princeton, New Jersey.

The Haley Enterprise

Series A in 2004
The Haley Enterprise is the recognized global leader in rule-based programming as well as a leading expert in automating managed knowledge within business solutions. The Haley Enterprise empowers business people to express, access, and maintain their business knowledge, best practices, and policies in plain English sentences. Haley's AI embeds these sentences within and integrates them with other information technology (IT) to automate their knowledge - without a software development cycle. Solutions from The Haley Enterprise operate on the full gamut of CPUs, from mainframes to hand-helds. With these capabilities, The Haley Enterprise offers businesses increased agility and reliability while at the same time improving profitability. Software from The Haley Enterprise is embedded in a variety of commercial software packages and applications by many of the world's largest companies. Haley's solutions are used broadly in customer relationship management (CRM) throughout the financial services sector, in telecommunications, and other industries.

LifeShield

Series A in 2004
LifeShield is the first national, professional grade and professionally monitored wireless security system that provides superior protection and the best value in home security. Other home security systems typically fall into two categories: cheap and ineffective or expensive and one-dimensional. Customers are fooled into thinking they are protected, but many burglars can actually defeat these cheap systems in under 30 seconds. And traditional alarm system companies charge thousands of dollars to put sensors on first floor windows and doors, and even more on bedroom windows and upstairs entry points. Most people simply can't afford what they really need. With LifeShield customers get better protection, reliability, and superior control compared to traditional analog-based security systems. Plus, LifeShield was one of the first to provide remote access to your home security system. With LifeShield, you have always been able to log into your system from anywhere in the world for free. Some of the other systems are finally able to offer you this same type of access, but you'll pay for it. They'll add an extra cost to your monthly monitoring payments. And with LifeShield you can access your system even more easily with apps for iPhone, Blackberry, and Android. Look for our iPod application launch coming in July. We make home protection easy and convenient. Specialties Home Security, Home Automation, Alarm Systems, Security System Installation, Home security systems

BPL Global

Venture Round in 2009
BPL Global provides electric utilities with a suite of smart grid solutions that support advanced distribution automation from substations through customer premises. Our solutions collaborate across the grid, helping utilities increase efficiency and reliability to improve their financial, operational and environmental performance. BPLG combines our experience in applying smart grid solutions with our market-leading technology to successfully serve leading utilities.

E-Duction

Series B in 2007
E-Duction is at the forefront of the evolving payment industry – paying for goods and services via payroll deduction. The current advent of consumerism is creating demand for more complex payroll deduction products, including variable and dynamic products in which the deduction/payment amount may change each month. E-Duction's transaction processing capabilities make possible a wide range of profitable, consumer-friendly payroll deduction-based services which meet the key demands of today's large and small employers alike.

SpeechVantage

Venture Round in 2002
Speechvantage develops and markets speech recognition and text-to-speech solutions. The company provides packaged and custom speech applications and services. Its flagship product, the OLIVE™ Suite of business applications, provides a speech-enabled auto attendant, a voice-activated emergency contact list, a speech-enabled password reset system, a voice-activated dialing system, and voice-activated Outlook & Lotus Notes. The company’s customers are SpeechWorks, Nuance, VoiceGenie, Avaya, BBN, Ann Taylor, Astra Zeneca, HIP, Mellon Financial Corp., University of Pennsylvania, and Bank of Nova Scotia. Speechvantage is based in Horsham, Pennsylvania.

eonDigital

Venture Round in 2000
eonDigital provides a web-based application which presents an intuitive environment for workgroup collaboration, project control, content management, digital rights protection and customized, on-demand publishing.

BPL Global

Venture Round in 2008
BPL Global provides electric utilities with a suite of smart grid solutions that support advanced distribution automation from substations through customer premises. Our solutions collaborate across the grid, helping utilities increase efficiency and reliability to improve their financial, operational and environmental performance. BPLG combines our experience in applying smart grid solutions with our market-leading technology to successfully serve leading utilities.

iMedium

Series B in 2000
IMedium, Inc. develops an Application Service Provider (ASP) that enables the delivery of highly visual, intuitive Web interactions to business customers, future clients and trading partners.

Nistica

Series C in 2010
Nistica is a global supplier of agile optical modules that simplify, automate and make affordable the delivery of high bandwidth applications. Founded in January 2005 with the vision of automating the edge and metro core of the optical network, Nistica has designed its products for optical system OEM vendors around the world.

BPL Global

Series C in 2007
BPL Global provides electric utilities with a suite of smart grid solutions that support advanced distribution automation from substations through customer premises. Our solutions collaborate across the grid, helping utilities increase efficiency and reliability to improve their financial, operational and environmental performance. BPLG combines our experience in applying smart grid solutions with our market-leading technology to successfully serve leading utilities.

Cernostics, Inc.

Venture Round in 2013
Cernostics is a life science company developing new molecular diagnostic tests for the fight against cancer. Most current diagnostic approaches offer a limited view of cancer because they fail to evaluate the tumor as a system composed of multiple cell types, not merely tumor cells. Its patent-protected technology platform, TissueCypher, uniquely analyzes whole slide digital images with multiplexed fluorescence, providing greater information and accuracy than traditional subjective tissue diagnostics.

Cernostics, Inc.

Series A in 2010
Cernostics is a life science company developing new molecular diagnostic tests for the fight against cancer. Most current diagnostic approaches offer a limited view of cancer because they fail to evaluate the tumor as a system composed of multiple cell types, not merely tumor cells. Its patent-protected technology platform, TissueCypher, uniquely analyzes whole slide digital images with multiplexed fluorescence, providing greater information and accuracy than traditional subjective tissue diagnostics.

Nistica

Series B in 2008
Nistica is a global supplier of agile optical modules that simplify, automate and make affordable the delivery of high bandwidth applications. Founded in January 2005 with the vision of automating the edge and metro core of the optical network, Nistica has designed its products for optical system OEM vendors around the world.

Internet Publishing Group

Venture Round in 2000
A provider of specialized market news and analysis for B2B Web sites.

iJET International

Series C in 2004
iJET was the first to introduce intelligence to the travel industry, which was then primarily focused on getting people from one location to another – not on keeping them safe during their trips. iJET began offering services that protected the individual traveler in March 2001, first through travel agencies and then to corporate travel departments. September 11, 2001 changed the way corporations thought about travelers and by the end of the year, iJET was protecting employees from 20 corporations.

Nistica

Series D in 2011
Nistica is a global supplier of agile optical modules that simplify, automate and make affordable the delivery of high bandwidth applications. Founded in January 2005 with the vision of automating the edge and metro core of the optical network, Nistica has designed its products for optical system OEM vendors around the world.