Two Sigma Ventures

Steadily is an online insurance platform that specializes in providing tailored landlord insurance coverage. Its offerings include protection against a variety of potential damages, such as those caused by weather, fire, water, vandalism, and liability for guest injuries and lawsuits. Steadily simplifies the insurance purchasing process by pre-filling essential data points like property size and year of construction, allowing landlords to obtain quotes and secure coverage directly through a mobile platform. This streamlined approach enhances the experience for property owners, enabling them to address their insurance needs efficiently without the need for intermediaries. Additionally, Steadily integrates with other property management solutions, contributing to a comprehensive suite of tools designed for short-term rental property managers.

Tive is a Boston-based startup that provides companies with end-to-end visibility into their supply chains through a sensor-driven tracking platform. The company develops a solution that combines cellular-connected trackers with cloud-based software, allowing clients to monitor, visualize, and optimize their operations in real-time. Tive's platform offers customized alerts, reporting, and analysis for both inbound and outbound shipments across various transportation modes. By enhancing supply chain transparency, Tive helps businesses improve efficiency, reduce logistics costs, and minimize manufacturing disruptions, ultimately enabling them to meet regulatory requirements effectively.

Terray Therapeutics, founded in 2018 and based in Pasadena, California, is a biotechnology company dedicated to advancing drug discovery for intractable diseases. It operates a unique platform that combines experimentation and computation to efficiently explore chemical space, generating precise data through rapid design-make-test-analyze cycles. The company employs artificial intelligence, synthetic chemistry, automation, and nanotechnology to create comprehensive datasets using ultra-dense microarray technology. These datasets systematically map biochemical interactions between small molecules and disease targets, enabling iterative cycles of virtual molecular design and experimentation that guide AI and machine learning models for predictive insights in drug discovery.

Distributional is a company focused on enhancing the safety, reliability, and security of artificial intelligence systems. It develops an AI testing and evaluation platform that offers tools for continuous monitoring, generating test cases, and analyzing results. This platform ensures that AI systems perform as intended, allowing organizations to trust their AI implementations. By providing these capabilities, Distributional enables customers to deploy AI products more frequently and harness the full potential of AI within their operations.

Arda Therapeutics is a biotechnology company focused on addressing chronic diseases and the effects of aging by targeting and eliminating pathogenic cells responsible for these conditions. Established in 2021 in the San Francisco Bay Area, the company utilizes single-cell data from patients to identify specific pathogenic cells and their markers. This precise identification allows Arda to develop therapies that aim to eradicate only those detrimental cells, thereby addressing the root causes of diseases while preserving healthy cells. By removing entire pathological networks, Arda Therapeutics strives to offer effective treatments that can lead to potential cures for patients suffering from chronic illnesses.

Crossover Markets Group is a digital asset exchange focused on addressing the liquidity requirements of institutional clients. The company has developed a trading platform that enhances the speed of cryptocurrency transactions and minimizes latency, aligning with the performance standards typically expected in traditional foreign exchange or equity markets. By enabling seamless cryptocurrency trading, Crossover Markets aims to support institutional investors in maintaining liquidity while navigating the digital asset landscape.

Vizzu is a software company that specializes in data visualization tools. Its flagship product transforms complex data into engaging, animated stories, combining data analysis and visualization steps to save users time and ensure impactful storytelling. Vizzu aims to make data analysis and presentation accessible and engaging for all, enabling data scientists and analysts to communicate complex insights clearly and effectively.

Gameto is a biotechnology company focused on advancing female reproductive health through innovative therapies. Recognizing the significant lack of treatment options in this underserved area, Gameto employs cutting-edge scientific techniques to develop solutions that enhance the quality of life for women. The company utilizes cellular engineering to create a platform that produces engineered ovarian and endometrial cell lines capable of mimicking the functions of natural cells, including hormone production and response. This platform underpins a portfolio of cellular therapeutics aimed at addressing various female reproductive diseases. Gameto's first initiative, Fertilo, targets improvements in in vitro fertilization (IVF) and egg freezing processes, striving to make them shorter, safer, and more effective. Additionally, the company is developing Deovo, an organoid model of the female reproductive system, and Ameno, a cell-based therapy designed to mitigate health issues related to primary ovarian insufficiency and menopause. Through these efforts, Gameto aims to transform the landscape of female reproductive health care.

Xaira Therapeutics is a biotechnology company based in the San Francisco Bay Area that focuses on leveraging artificial intelligence to enhance drug discovery and development. The company integrates machine learning research, extensive biological and clinical data generation, and therapeutic product development to innovate how diseases are treated. By employing advanced AI methodologies, Xaira aims to transform the traditional drug development process, enabling the creation of more effective therapies. Through its multidisciplinary approach, the company seeks to advance understanding of biology and improve the overall efficiency of developing new treatments.

Nullify specializes in developing artificial intelligence agents tailored for autonomous application security tasks. These AI-driven solutions emulate the reasoning and decision-making abilities of human security engineers, enabling organizations to enhance their software security without needing to increase the size of their security teams. With a significant imbalance between the number of software engineers and security engineers, alongside a growing cyber skills shortage, Nullify addresses the challenges of cost, efficiency, and scalability in product security. The company's platform provides an integrated suite of security testing tools that streamline processes such as testing, prioritization, remediation, and threat modeling, allowing product security teams to concentrate on more strategic and impactful security initiatives. By automating these critical tasks, Nullify contributes to the development of secure software, which is increasingly vital for national security.

Treet operates a peer-to-peer resale marketplace designed to assist apparel brands in adopting circular economy practices and managing their secondhand market. By providing a platform where customers can buy and sell used items directly with one another, Treet creates additional revenue opportunities for brands while enhancing customer loyalty. The company oversees all logistics and support, allowing brands to focus on their core business while benefiting from the resale experience. This approach enables e-commerce brands to promote sustainability and take ownership of their secondhand sales, transforming used products into valuable offerings that feel new to consumers.

Anomalo is a developer of an artificial intelligence data validation tool that enables users to continuously inspect and validate data entering their warehouses. The company’s solution automatically detects and explains issues in enterprise data, facilitating seamless integration with data warehouses. By employing automated machine learning technology, Anomalo’s tool allows organizations to validate and document their data with minimal configuration, eliminating the need for users to write any code. This innovation helps companies maintain data integrity and improve the reliability of their data-driven decisions.

Ansel Health is a company that develops a health insurance platform designed to improve employee benefits for employers through a straightforward supplemental health benefits plan. The platform provides insurance services that offer financial support in the form of cash payments to individuals diagnosed with various covered conditions, including those related to COVID-19. This support aims to help mitigate the financial challenges associated with serious health issues, facilitating a smoother recovery process for affected individuals.

Distributional is a company focused on enhancing the safety, reliability, and security of artificial intelligence systems. It develops an AI testing and evaluation platform that offers tools for continuous monitoring, generating test cases, and analyzing results. This platform ensures that AI systems perform as intended, allowing organizations to trust their AI implementations. By providing these capabilities, Distributional enables customers to deploy AI products more frequently and harness the full potential of AI within their operations.

Developer of artificial intelligence-driven solar cell technology platform designed to build next-generation cells. The company's platform technology offers perovskite silicon tandem solar cells that are optimized and improved based on data from those that came before and provides mainstream silicon technology that has a combination of materials and processes to reach its fundamental limits, enabling clients with new solar and semiconductor technologies in a fraction of the time and cost, compared to conventional methods.

Objective is a company that specializes in AI-native search solutions for websites and applications. It has developed a low-code platform designed to facilitate the creation of multi-search applications. Through its innovative SaaS API, Objective enables users to unlock advanced search and enrichment capabilities for various types of data, including images, text, and video. The platform allows users to conduct searches using natural language or a combination of data types, streamlining the search process and enhancing user experience.

Membrane Labs is a fintech firm that provides institutional digital asset services for OTC transactions.

Cerby, Inc. is a cybersecurity company founded in 2020 and based in Alameda, California. It specializes in developing tools and applications aimed at managing access for disconnected applications and addressing the risks associated with Shadow IT. Cerby offers a comprehensive access management platform that leverages identity providers to automate security tasks and improve identity and access management processes. This platform eliminates the reliance on manual tools and compensating controls, streamlining tasks such as offboarding and two-factor authentication enrollment. With its patent-pending access orchestration engine, Cerby provides organizations with passwordless authentication capabilities and enhanced visibility over applications that do not conform to standard protocols. By automating these processes, Cerby enables identity teams to extend access, minimize security risks, and reduce operational costs while adhering to zero trust principles.

Raincoat is a company focused on developing scalable embedded climate insurance products, supported by an automated infrastructure. It partners with insurers, reinsurers, governments, and financial institutions to create and distribute parametric insurance solutions. By facilitating instant payouts on catastrophe policies, Raincoat aims to enhance financial resilience for businesses affected by natural disasters. The company’s approach seeks to unlock new markets and promote climate resilience on a broad scale.

Building the hyperverse. We let people stream, make content, and make friends as an avatar.

Omni Network is a blockchain that supports applications in functioning across all rollups. The company creates technologies that support personal freedoms and enable global collaboration.

NetBox Labs is a company focused on simplifying the management of complex networks for operators through its innovative products. Its flagship offering, NetBox Cloud, is an enterprise-grade, software-as-a-service (SaaS) version of the open-source NetBox, designed to enhance network automation. The platform serves as a central database that allows users to query data efficiently, providing consistent and accurate answers. By enforcing physical and logical rules related to network management, NetBox Labs helps clients streamline their operations, reduce manual errors, and eliminate the inefficiencies associated with traditional spreadsheet-based approaches.

Crossover Markets Group is a digital asset exchange focused on addressing the liquidity requirements of institutional clients. The company has developed a trading platform that enhances the speed of cryptocurrency transactions and minimizes latency, aligning with the performance standards typically expected in traditional foreign exchange or equity markets. By enabling seamless cryptocurrency trading, Crossover Markets aims to support institutional investors in maintaining liquidity while navigating the digital asset landscape.

C3 is a self-custodial exchange that combines the advantages of self-custody and decentralization with the performance and accessibility expected from traditional trading platforms. It is designed to facilitate trading in both spot and derivatives markets. The platform features a sophisticated clearing engine that supports cross-margin and cross-collateralization, allowing traders to manage their capital more efficiently by calculating margin requirements globally based on their open positions. With its focus on enhancing user experience, C3 aims to provide a secure and efficient environment for trading digital assets.

Freeform is a 3D printing company specializing in metal 3D printing solutions tailored for manufacturing industries. The company develops innovative machines designed to integrate the scalability of software with physical production processes. Utilizing a proprietary technology stack that incorporates advanced sensing, real-time controls, and data-driven learning, Freeform enables the production of digitally verified and flawless parts. This technology allows manufacturers to efficiently transition from concept to volume production, significantly enhancing speed and reducing costs. By deploying self-sufficient metal 3D printing factories globally, Freeform aims to democratize access to the transformative benefits of 3D printing across various sectors.

Crux Informatics Inc. is a data processing and management company founded in 2017 and based in San Francisco, California. It specializes in providing an external data automation platform that facilitates the integration, transformation, and observability of third-party data. Crux's cloud-based solution bridges the operational gap between data suppliers and consumers, automating the development of data pipelines and ensuring ongoing validation of data quality. The platform supports companies in efficiently managing data operations at scale, leveraging advanced technology and a team of experienced data engineers to enhance external data integration workflows.

Osmo is a company that develops an artificial intelligence platform designed to give computers a sense of smell. By combining advanced AI with olfactory science, Osmo addresses significant challenges in the fragrance industry while also aiming to enhance human health and well-being. The company creates aroma molecules for a variety of products, including perfumes, shampoos, lotions, and candles. Additionally, Osmo's technology has the potential to detect diseases earlier and track pandemics, thereby improving consumer experience and overall wellness. Through its innovative approach, Osmo seeks to transform the way scent is integrated into everyday life and contribute positively to public health.

Rive is a company focused on enhancing collaboration between designers and developers through its real-time animation platform. This platform allows for the creation of animated interactive experiences that are faster, smaller, and more memory-efficient than traditional design solutions. By enabling designers to produce interactive content from concept to production, Rive simplifies the workflow and reduces the need for complex handoffs between teams. The platform facilitates the design and animation of various graphics, including animated user interfaces, characters, and icons, making it easier for creative teams to iterate freely. Overall, Rive's innovative tools streamline the development of high-quality animation for applications and games, saving businesses both time and engineering resources.

Enveda Biosciences is a biotechnology company that employs artificial intelligence-powered tools to investigate and define molecules sourced from living organisms. Its primary objective is to build an exhaustive database of chemical biodiversity, thereby expediting the discovery of novel medicines. The company's innovative drug discovery platform integrates machine learning, metabolomics, and robotics to analyze natural samples for both chemical structure and biological activity, eliminating the need for isolating individual compounds or extensive experimentation. This enables healthcare industry clients to develop a wide range of new medications, from antibiotics to hypotensives.

Cajal Neuroscience is a biotechnology company focused on developing innovative therapies for neurodegenerative diseases. It employs a combination of human genetics, functional genomics, and advanced microscopy techniques to identify novel targets and therapeutics. The company utilizes viral tools and platforms for screening targets that influence the progression of neurodegenerative conditions, alongside functional genetic screening and multi-omics methods. By integrating these state-of-the-art approaches, Cajal Neuroscience aims to advance precision medicine, ultimately enabling healthcare professionals to improve treatment outcomes for patients suffering from neurodegenerative disorders.

Hexagon Bio, Inc. is a biotechnology company that specializes in discovering novel small molecule therapeutics by mining genomic data from fungal genomes. Founded in 2016 and headquartered in Menlo Park, California, Hexagon Bio leverages a proprietary platform that integrates data science, synthetic biology, and automation to identify and engineer drugs. The company's innovative approach focuses on developing targeted therapies for diseases with unmet medical needs by searching for evolutionarily refined molecules and their associated protein targets. Through its unique methodology, Hexagon Bio aims to uncover new medicines encoded within the global metagenome, ultimately striving to improve patient outcomes.

Flatfile Inc. is a company that specializes in data onboarding solutions, enabling developers to efficiently validate, map, and import CSV data from various web applications. Founded in 2018 and based in Denver, Colorado, Flatfile offers a platform that integrates seamlessly with software applications, allowing users to upload data through formats such as CSV, XLS, or TSV. Its key products include Portal, which provides an import button embedded via a JavaScript snippet, and Concierge, which creates secure collaborative workspaces for organizations to manage complex data ingestion challenges. The platform is designed to enhance developer productivity, reduce costs, and improve data quality by learning to identify and clean incoming data over time. Numerous companies, including AstraZeneca and Square, utilize Flatfile’s API-first platform to streamline their data import processes.

Hivemind Technologies AG is a technology company based in Cologne, Germany, specializing in the development of social video platforms and mobile applications. The company offers a range of application programming interface (API) solutions, including topic identification, social metrics, language detection, and news APIs. Hivemind Technologies also provides tools for publishers, such as Virato analytics for tracking and comparing articles, news widgets for integrating relevant feeds, and newsroom dashboards for displaying social news performance. Furthermore, the company delivers consulting services that assist clients in understanding data flows, selecting appropriate technology stacks, and designing automated processes. Hivemind Technologies aims to help businesses modernize their technology infrastructure and leverage machine learning to analyze and manage large volumes of data. Founded in 2011, the company was formerly known as Alpha 12.

Xilis, Inc. is a biotechnology company founded in 2019 and based in Chapel Hill, North Carolina. The company specializes in developing next-generation organoid technologies aimed at guiding precision therapy for cancer patients and enhancing drug discovery processes. Its flagship platform, XilisµO, facilitates rapid diagnostics, personalized drug screening, and the creation of scalable patient-derived models, which support high-throughput drug discovery. By enabling both physicians and pharmaceutical companies to conduct tailored drug screenings, Xilis aims to lower costs and improve treatment outcomes for cancer patients.

Isabl is a startup focused on developing advanced diagnostic assays for cancer through whole-genome and RNA sequencing. Founded in 2020 after incubating its technology at Memorial Sloan Kettering Cancer Center from 2015 to 2019, Isabl participated in the Winter 2020 batch of Y Combinator and has attracted significant funding, including a $3 million seed round and a $2 million SBIR grant from the National Cancer Institute. The company received FDA Breakthrough Device designation in 2021, recognizing the innovative nature of its cancer diagnostic tests. Isabl's platform is designed to efficiently analyze cancer patients' genomes while ensuring data reproducibility and supporting bioinformatics operations, thereby facilitating data-driven automation for oncology centers. Led by founders Dr. Elli Papaemmanuil, Dr. Andrew Kung, and Juan Medina, Isabl's team combines expertise in precision medicine, computational biology, and software engineering, focusing on biomarker discovery and clinical decision support for pediatric and rare solid cancers.

Tive is a Boston-based startup that provides companies with end-to-end visibility into their supply chains through a sensor-driven tracking platform. The company develops a solution that combines cellular-connected trackers with cloud-based software, allowing clients to monitor, visualize, and optimize their operations in real-time. Tive's platform offers customized alerts, reporting, and analysis for both inbound and outbound shipments across various transportation modes. By enhancing supply chain transparency, Tive helps businesses improve efficiency, reduce logistics costs, and minimize manufacturing disruptions, ultimately enabling them to meet regulatory requirements effectively.

Remote is a global HR solutions provider that facilitates international hiring and payroll management for distributed teams. They offer a platform designed to help companies recruit top talent worldwide, ensuring compliance with local laws while streamlining project allocation and payments. This enables businesses to expand their workforce globally, enhancing productivity and employment opportunities.

Okteto Inc. is a computer software company that specializes in cloud application development for Kubernetes. Founded in 2018 and based in San Francisco, California, Okteto provides a platform that allows developers to instantly create and manage pre-configured environments in the cloud. Its flagship product, Okteto Enterprise, offers self-service access to Kubernetes infrastructure, enabling users to visualize workloads through a developer-focused dashboard. The platform applies security policies, manages access control, and creates secure namespaces for deployments. Additionally, Okteto facilitates automatic HTTPS endpoints for services, secret management to safeguard credentials, and seamless integration with the Okteto CLI for direct development within Kubernetes clusters. This comprehensive approach allows clients to rapidly iterate and enhance their cloud-based applications.

Timescale, Inc., established in 2011 and headquartered in New York with offices in Stockholm and Los Angeles, specializes in data analysis platforms designed for scale, ease of use, and complex queries. Its flagship product, TimescaleDB, is an open-source time-series database that supports full SQL, optimized for advanced analytics and production use cases. Timescale serves software developers and businesses worldwide, enabling them to build and analyze time-series and machine data applications.

Kallyope Inc. is a biotechnology company based in New York City that focuses on understanding the gut-brain axis to develop innovative therapeutics and consumer products aimed at enhancing human health. Established in 2014, Kallyope employs advanced technologies, including sequencing, computational biology, neural imaging, and human genetics, to explore gut-brain biology. The company aims to address significant unmet medical needs, such as diabetes, obesity, gut disorders, inflammatory diseases, migraines, and allergies, by creating effective and user-friendly oral agents. Kallyope's team consists of experienced scientists from leading institutions, working alongside a skilled team with a strong track record in drug discovery and development. Through its research, Kallyope seeks to deliver transformative solutions that improve overall health outcomes.

Terray Therapeutics, founded in 2018 and based in Pasadena, California, is a biotechnology company dedicated to advancing drug discovery for intractable diseases. It operates a unique platform that combines experimentation and computation to efficiently explore chemical space, generating precise data through rapid design-make-test-analyze cycles. The company employs artificial intelligence, synthetic chemistry, automation, and nanotechnology to create comprehensive datasets using ultra-dense microarray technology. These datasets systematically map biochemical interactions between small molecules and disease targets, enabling iterative cycles of virtual molecular design and experimentation that guide AI and machine learning models for predictive insights in drug discovery.

Radar is a location data infrastructure platform that enables app developers to create location-aware experiences. Founded in 2016 and headquartered in New York, the company provides a suite of tools, including geofencing, place detection, and location tracking, to enhance mobile applications across various industries such as retail, travel, and logistics. Radar's platform features APIs and SDKs that facilitate easy integration, allowing developers to implement contextually relevant functionalities in their applications. With a strong focus on privacy and security, Radar ensures that location data is managed responsibly. The company also offers additional APIs in private beta, including geocoding, which converts addresses to coordinates, and tools for searching geofences and calculating distances between locations.

Rift Finance is a decentralized protocol focused on enhancing the growth of Decentralized Autonomous Organizations (DAOs) through innovative incentive structures. The company provides a financial platform that enables DAOs to deploy governance tokens from their treasuries, thereby increasing token liquidity without relinquishing ownership. This approach assists crypto companies in achieving their liquidity objectives while offering potentially attractive and safer returns for liquidity providers. By streamlining the process of token management, Rift Finance plays a crucial role in the evolving landscape of WEB3 financial services.

Figment Networks Inc. is a leading blockchain infrastructure and software provider based in Toronto, Canada, established in 2018. The company develops and operates an open-source crypto network, focusing on enhancing community engagement through tools that facilitate understanding of network health and performance for informed staking decisions. Figment supports various crypto networks, including Tezos, Cosmos, Livepeer, and Horizen. It offers a comprehensive suite of services, such as enterprise-grade node and staking infrastructure, the Hubble Web 3 explorer, and DataHub developer APIs, aimed at simplifying the use, development, and governance of blockchains for token holders and developers alike. Additionally, Figment publishes open-source software and economic research to further benefit the blockchain community.

Exai Bio is a next-generation liquid biopsy company that specializes in the early diagnosis of cancer through its proprietary RNA-based platform. This innovative platform focuses on the analysis of cell-free RNA profiles, particularly orphan non-coding RNA and small RNA sequences that are typically absent in normal tissues but prevalent in tumors. By leveraging advanced artificial intelligence and machine learning algorithms, Exai Bio provides clinical insights into cancer biology, enabling healthcare professionals to identify cancer accurately and at its earliest stages. The company's approach not only enhances diagnostic precision but also informs personalized care treatments for patients.

NewtonX, Inc. is a B2B market research company that connects professional services firms and financial institutions with verified business expertise. Founded in 2016 and based in New York, NewtonX utilizes an advanced algorithm known as the NewtonX Graph, which leverages artificial intelligence to recruit the ideal audience for specific business inquiries from a vast network of over 1.1 billion professionals across 140 industries. The company ensures that every professional is thoroughly verified, enabling clients to make informed decisions. NewtonX offers a range of services, including large-scale quantitative surveys, qualitative expert interviews, long-term consultations, and tailored research plans. Through its platform, NewtonX Prime, clients gain instant access to expert insights, enhancing their competitive advantage. The company collaborates with Fortune 500 companies, top consultancies, marketers, and investors, aiming to set a new standard for truth in B2B insights.

Comet ML Inc. is a New York-based company that provides a meta machine learning platform designed to assist data science teams and individuals in building reliable machine learning models for real-world applications. The platform enables users to automatically track datasets, code changes, experimentation history, and production models, thereby enhancing efficiency, transparency, and reproducibility in the machine learning process. By allowing data scientists to maintain their preferred workflows while effectively collaborating and tracking previous work, Comet facilitates a more organized approach to experimentation. Additionally, the platform incorporates bayesian hyperparameter optimization, which streamlines the model tuning process and reduces the time typically required for manual adjustments. This comprehensive solution increases visibility into data science efforts and improves the overall effectiveness of machine learning initiatives within organizations.

Facet is a computer software company that provides artists and engineers, aiming to redefine and humanize the creative process.

Socure Inc. is a provider of digital identity verification solutions, focusing on real-time identity authentication through its Socure ID+ platform. This predictive analytics platform utilizes artificial intelligence and machine learning to authenticate identities by analyzing a multitude of online and offline data sources, including email, phone numbers, addresses, IP addresses, and social media profiles. Socure's offerings include Aida, an AI-driven bot for validating digital identities, Docv, an omnichannel document verification solution, and Sigma Synthetic Fraud, which tackles synthetic identity fraud. The company addresses the needs of various sectors, including software, consulting, and financial firms, through compliance initiatives such as customer identification programs, know your customer requirements, and anti-money laundering measures. Founded in 2012 and headquartered in New York, Socure has established partnerships with key industry players to enhance its service delivery.

RightRev is a developer of an automated revenue recognition platform that enhances financial reporting accuracy and compliance for businesses. The solution integrates various processes, including customer relationship management and configure-price-quote tools, with revenue accounting and general ledger systems. This unified platform streamlines the management of revenue contracts, enabling finance professionals to track all aspects of sales and revenue reporting effectively. By facilitating adherence to accounting standards such as ASC 606 and IFRS 15, RightRev helps businesses minimize the risk of misstatements while ensuring transparency in their financial operations. The platform supports a wide range of revenue models, including subscriptions, one-time sales, services, and promotions, making it a versatile tool for sales operations and revenue management.

Anomalo is a developer of an artificial intelligence data validation tool that enables users to continuously inspect and validate data entering their warehouses. The company’s solution automatically detects and explains issues in enterprise data, facilitating seamless integration with data warehouses. By employing automated machine learning technology, Anomalo’s tool allows organizations to validate and document their data with minimal configuration, eliminating the need for users to write any code. This innovation helps companies maintain data integrity and improve the reliability of their data-driven decisions.

Nelo is a Mexico City-based company that specializes in developing a mobile application for financial transactions. Founded on April 8, 2019, Nelo offers a digital payment management platform that enables users to track their financial transactions effectively. The platform allows individuals to send and request money while providing a free virtual card with no charges for account opening. This functionality facilitates real-time payment and balance tracking, empowering users to manage their funds in an affordable and secure manner.

Eclipse Advantage is a specialized warehouse labor management company that serves the foodservice and retail sectors in North America. Operating across 55 sites in the U.S. and Canada, it offers a range of services including in-bound receiving, pallet management, and order selection. By providing outsourced supply chain workforce solutions, Eclipse Advantage enhances productivity and delivers transparency in labor expenses for warehouses and distribution centers. The company is dedicated to high-quality service, guided by its core values of serving customers, ensuring safety, and achieving success.

Sora is a low-code intelligent workflow automation and data integration tool that connects different corporate applications such as HR, IT, and other systems and data sets to provide a smarter, more user-friendly experience for employees, business owners, and HR professionals.

Replicated, Inc. is a company that specializes in providing tools for the deployment and management of third-party applications within enterprise environments. Founded in 2014 and headquartered in Culver City, California, Replicated offers a solution for organizations seeking to install and operate Software as a Service (SaaS) applications securely within their own firewalls. By enabling software vendors to deliver cloud-native applications in on-premises data centers or private clouds, Replicated enhances security and control for its clients. The company's offerings facilitate the management and support of these applications, ultimately simplifying the customer support process for businesses.

Hexagon Bio, Inc. is a biotechnology company that specializes in discovering novel small molecule therapeutics by mining genomic data from fungal genomes. Founded in 2016 and headquartered in Menlo Park, California, Hexagon Bio leverages a proprietary platform that integrates data science, synthetic biology, and automation to identify and engineer drugs. The company's innovative approach focuses on developing targeted therapies for diseases with unmet medical needs by searching for evolutionarily refined molecules and their associated protein targets. Through its unique methodology, Hexagon Bio aims to uncover new medicines encoded within the global metagenome, ultimately striving to improve patient outcomes.

Castor is an international health-tech company that provides a cloud-based clinical data platform designed to streamline the clinical trial process for researchers globally. Founded by CEO Derk Arts, MD, Ph.D., the platform is utilized by over 50,000 researchers in 90 countries, supporting more than 4,000 studies across diverse therapeutic areas, including diabetes, cardiovascular disease, rare diseases, infectious diseases, and oncology. Castor's platform facilitates the collection and analysis of extensive data from both traditional and remote trials, having reached significant milestones such as 180 million data points and 2 million enrolled patients. The company's mission is to make research data reusable, thereby enabling AI-driven clinical trials and enhancing the overall impact of data within the medical research community.

Remote is a global HR solutions provider that facilitates international hiring and payroll management for distributed teams. They offer a platform designed to help companies recruit top talent worldwide, ensuring compliance with local laws while streamlining project allocation and payments. This enables businesses to expand their workforce globally, enhancing productivity and employment opportunities.

Xilis, Inc. is a biotechnology company founded in 2019 and based in Chapel Hill, North Carolina. The company specializes in developing next-generation organoid technologies aimed at guiding precision therapy for cancer patients and enhancing drug discovery processes. Its flagship platform, XilisµO, facilitates rapid diagnostics, personalized drug screening, and the creation of scalable patient-derived models, which support high-throughput drug discovery. By enabling both physicians and pharmaceutical companies to conduct tailored drug screenings, Xilis aims to lower costs and improve treatment outcomes for cancer patients.

Terray Therapeutics, founded in 2018 and based in Pasadena, California, is a biotechnology company dedicated to advancing drug discovery for intractable diseases. It operates a unique platform that combines experimentation and computation to efficiently explore chemical space, generating precise data through rapid design-make-test-analyze cycles. The company employs artificial intelligence, synthetic chemistry, automation, and nanotechnology to create comprehensive datasets using ultra-dense microarray technology. These datasets systematically map biochemical interactions between small molecules and disease targets, enabling iterative cycles of virtual molecular design and experimentation that guide AI and machine learning models for predictive insights in drug discovery.

Enveda Biosciences is a biotechnology company that employs artificial intelligence-powered tools to investigate and define molecules sourced from living organisms. Its primary objective is to build an exhaustive database of chemical biodiversity, thereby expediting the discovery of novel medicines. The company's innovative drug discovery platform integrates machine learning, metabolomics, and robotics to analyze natural samples for both chemical structure and biological activity, eliminating the need for isolating individual compounds or extensive experimentation. This enables healthcare industry clients to develop a wide range of new medications, from antibiotics to hypotensives.

Formlogic is an autonomous manufacturing technology company focused on delivering precision components for the space and frontier industries. By addressing the challenges of the domestic supply chain, Formlogic enhances manufacturing capabilities, allowing both novice and expert workers to achieve high levels of precision and productivity. The company's technology enables rapid turnaround times for custom machined components, with production orders completed in weeks rather than months. Additionally, Formlogic provides real-time order status updates, improving the overall customer experience. Through its innovative approach, Formlogic aims to revolutionize the manufacturing process, ensuring close tolerances and efficient production at scale.

Appia Bio is a biotechnology company dedicated to the research and development of off-the-shelf allogeneic cell therapies, with a particular focus on engineered allogeneic cell therapies for various medical indications. The company utilizes its proprietary ACUA technology platform to harness the biology of lymphocyte development, integrating chimeric antigen receptor (CAR) and T-cell receptor (TCR) gene engineering. This innovative approach allows Appia Bio to generate CAR-engineered invariant natural killer T (CAR-iNKT) cell subtypes derived from hematopoietic stem cells (HSCs). By maturing and scaling healthy stem cells into invariant T-cell therapies, Appia Bio aims to provide physicians with safe and targeted cancer treatment options, thereby expanding patient access to advanced therapeutic solutions.

Text Blaze is a productivity platform that enables users to create and utilize programmable text snippets, enhancing efficiency in typing and workflows. By allowing users to insert these snippets anywhere on the web via keyboard shortcuts, Text Blaze helps eliminate repetitive typing and reduce errors. The platform supports various snippet types, including plain text, dynamic user input, and business logic, alongside no-code integrations with other applications. Additionally, Text Blaze features collaboration tools that facilitate sharing and customizing templates, allowing teams to optimize their productivity and streamline their work processes.

Timescale, Inc., established in 2011 and headquartered in New York with offices in Stockholm and Los Angeles, specializes in data analysis platforms designed for scale, ease of use, and complex queries. Its flagship product, TimescaleDB, is an open-source time-series database that supports full SQL, optimized for advanced analytics and production use cases. Timescale serves software developers and businesses worldwide, enabling them to build and analyze time-series and machine data applications.

Wealthsimple Financial Inc. is a Toronto-based company that specializes in providing digital investment advisory services across Canada and operates additional offices in Brooklyn, New York, and London, United Kingdom. Founded in 2014, Wealthsimple offers a range of financial tools designed to help investors grow and manage their money. The company builds diversified portfolios of exchange-traded funds (ETFs) on behalf of its clients, offering accessible and affordable investment management without the high fees and account minimums typical of traditional firms. Wealthsimple also provides on-demand financial planning solutions and a hybrid savings and spending product known as Wealthsimple Cash. As of September 2020, Wealthsimple operates as a subsidiary of Purpose Advisor Solutions Inc.

Wholesale Supplies Plus, Inc. is an online retailer specializing in supplies for soapmaking and cosmetic production. Established in 1999 and headquartered in Independence, Ohio, the company provides a wide range of products, including cosmetic additives, pre-made bases, colorants, essential oils, flavor oils, fragrance oils, molds, containers, packaging, and various kits for projects. By offering these materials, Wholesale Supplies Plus enables customers to create personalized personal care products tailored to their specific needs.

Ansel Health is a company that develops a health insurance platform designed to improve employee benefits for employers through a straightforward supplemental health benefits plan. The platform provides insurance services that offer financial support in the form of cash payments to individuals diagnosed with various covered conditions, including those related to COVID-19. This support aims to help mitigate the financial challenges associated with serious health issues, facilitating a smoother recovery process for affected individuals.

Boundless Immigration is a Seattle-based company founded in 2017 that focuses on simplifying the immigration process for individuals, families, and businesses. It offers an innovative platform that empowers users to navigate the complexities of the immigration system with confidence and ease. By providing expert legal guidance and personalized support, Boundless ensures that clients have access to the necessary tools and information for their immigration journey. The company's commitment to affordability and accessibility allows users to connect with immigration lawyers and file their applications online, streamlining what can often be a challenging experience.

Per Diem is a technology company that provides local businesses with a mobile application designed to facilitate online subscriptions and enhance customer engagement. The app enables restaurants to streamline the ordering process, allowing customers to place orders directly and more frequently. In addition to order management, the platform includes features such as rewards tracking and notifications, which help businesses foster customer loyalty. Per Diem also offers marketing and fulfillment tools that empower local businesses to create a subscription model similar to that of major services, thereby enabling them to generate recurring revenue through monthly and annual subscriptions.

Facet is a computer software company that provides artists and engineers, aiming to redefine and humanize the creative process.

Comet ML Inc. is a New York-based company that provides a meta machine learning platform designed to assist data science teams and individuals in building reliable machine learning models for real-world applications. The platform enables users to automatically track datasets, code changes, experimentation history, and production models, thereby enhancing efficiency, transparency, and reproducibility in the machine learning process. By allowing data scientists to maintain their preferred workflows while effectively collaborating and tracking previous work, Comet facilitates a more organized approach to experimentation. Additionally, the platform incorporates bayesian hyperparameter optimization, which streamlines the model tuning process and reduces the time typically required for manual adjustments. This comprehensive solution increases visibility into data science efforts and improves the overall effectiveness of machine learning initiatives within organizations.

Tive is a Boston-based startup that provides companies with end-to-end visibility into their supply chains through a sensor-driven tracking platform. The company develops a solution that combines cellular-connected trackers with cloud-based software, allowing clients to monitor, visualize, and optimize their operations in real-time. Tive's platform offers customized alerts, reporting, and analysis for both inbound and outbound shipments across various transportation modes. By enhancing supply chain transparency, Tive helps businesses improve efficiency, reduce logistics costs, and minimize manufacturing disruptions, ultimately enabling them to meet regulatory requirements effectively.

Cylera, Inc. is a cybersecurity company specializing in protecting healthcare organizations from cyber threats and malware. Founded in 2017 and based in New York, Cylera offers a comprehensive platform that integrates advanced cybersecurity solutions tailored for the Internet of Things (IoT) in healthcare. The company's patented technology enables asset management, risk analysis, and threat detection, providing a centralized approach to cybersecurity. By identifying all connected devices within healthcare environments, Cylera's software analyzes risks and vulnerabilities, allowing organizations to respond to threats in real-time. This holistic, asset-centric platform aids healthcare providers, enterprises, and government agencies in enhancing their cybersecurity posture and ensuring the safety of critical medical devices and data.

Socure Inc. is a provider of digital identity verification solutions, focusing on real-time identity authentication through its Socure ID+ platform. This predictive analytics platform utilizes artificial intelligence and machine learning to authenticate identities by analyzing a multitude of online and offline data sources, including email, phone numbers, addresses, IP addresses, and social media profiles. Socure's offerings include Aida, an AI-driven bot for validating digital identities, Docv, an omnichannel document verification solution, and Sigma Synthetic Fraud, which tackles synthetic identity fraud. The company addresses the needs of various sectors, including software, consulting, and financial firms, through compliance initiatives such as customer identification programs, know your customer requirements, and anti-money laundering measures. Founded in 2012 and headquartered in New York, Socure has established partnerships with key industry players to enhance its service delivery.

Insitro, Inc. is a data-driven company focused on drug discovery and development, particularly targeting nonalcoholic steatohepatitis (NASH). Founded in 2018 by Daphne Koller and based in South San Francisco, California, Insitro harnesses machine learning and high-throughput biology to revolutionize the process of drug discovery. The company creates extensive functional genomic data sets and integrates them with patient data through innovative machine learning techniques. This approach allows Insitro to build predictive models that enhance target selection, streamline the design of therapeutics, and optimize drug development strategies. By addressing critical challenges in pharmaceutical research and development, Insitro aims to accelerate the delivery of new and effective treatments to patients.

Flatfile Inc. is a company that specializes in data onboarding solutions, enabling developers to efficiently validate, map, and import CSV data from various web applications. Founded in 2018 and based in Denver, Colorado, Flatfile offers a platform that integrates seamlessly with software applications, allowing users to upload data through formats such as CSV, XLS, or TSV. Its key products include Portal, which provides an import button embedded via a JavaScript snippet, and Concierge, which creates secure collaborative workspaces for organizations to manage complex data ingestion challenges. The platform is designed to enhance developer productivity, reduce costs, and improve data quality by learning to identify and clean incoming data over time. Numerous companies, including AstraZeneca and Square, utilize Flatfile’s API-first platform to streamline their data import processes.

Penn Foster College, Penn Foster Career School, and Penn Foster High School are part of Penn Foster, Inc., a global leader in online education. For more than 118 years, Penn Foster has been providing accredited career-focused degree and vocational programs in the fields of allied health, business, technology, education, and select trades. Nationally and regionally accredited Penn Foster High School (www.PennFosterHighSchool.com) and Penn Foster Career School (www.pennfoster.edu) are headquartered in Scranton, PA, with regional offices in Montreal, Canada. Penn Foster College is headquartered in Scottsdale, Arizona.

UMA is a decentralized platform focused on facilitating financial contracts with the aim of providing global market access. It enables the trading of derivative products, allowing users to create customized financial instruments without the need for a centralized authority. The platform operates as a reliable oracle, capable of recording verifiable truths and data on a blockchain. This structure not only promotes the automatic enforcement of contracts but also ensures instant settlement, reducing the risks associated with traditional financial systems. UMA's innovative approach empowers customers to transfer risk seamlessly across the internet while maintaining transparency and security in their transactions.

Smartfrog Group, established in 2015, is a pioneering consumer IoT SaaS company with a global presence in over 180 countries. Headquartered in New York City, the group's mission is to make modern technologies accessible, user-friendly, affordable, and secure for everyone. Smartfrog Group launched the world's first 100% consumer IoT SaaS product, offering an affordable DIY smart home security subscription service starting at $7/month, including a free device. In 2018, the group expanded to the US and acquired Canary Connect, merging the two businesses. Smartfrog Group's end-to-end controlled and protected full-stack platform enables data-driven businesses, offering SaaS solutions across various product areas, supporting individuals throughout their lives, from infancy to seniority. The group's business initially focused on smart home security and is gradually expanding to new verticals such as smart locks and access, last-mile in-home delivery, baby and child care, pet care, and elder and healthcare. Smartfrog Group grows both organically and through strategic mergers and acquisitions.

Tive is a Boston-based startup that provides companies with end-to-end visibility into their supply chains through a sensor-driven tracking platform. The company develops a solution that combines cellular-connected trackers with cloud-based software, allowing clients to monitor, visualize, and optimize their operations in real-time. Tive's platform offers customized alerts, reporting, and analysis for both inbound and outbound shipments across various transportation modes. By enhancing supply chain transparency, Tive helps businesses improve efficiency, reduce logistics costs, and minimize manufacturing disruptions, ultimately enabling them to meet regulatory requirements effectively.

Candu is a product experience platform founded in 2018 by Jonathan Anderson and Michele Riccardo Esposito. It enables software teams to design, refine, and personalize user interfaces for their applications, facilitating effective onboarding and user engagement. The platform features a drag-and-drop editor and an analytics suite that allows teams to customize user experiences without the need for coding. Candu's extensive UI component library empowers teams to build tailored experiences, while its analytics tools help measure the impact of these experiences on feature discovery and user adoption. Additionally, Candu supports the creation of in-product courses and just-in-time training, enabling non-technical teams to embed educational content and track user behavior, ultimately fostering product-led experiences and rapid experimentation.

Remote is a global HR solutions provider that facilitates international hiring and payroll management for distributed teams. They offer a platform designed to help companies recruit top talent worldwide, ensuring compliance with local laws while streamlining project allocation and payments. This enables businesses to expand their workforce globally, enhancing productivity and employment opportunities.

Whoop, Inc. is a Boston-based company that specializes in the development and sale of wearable fitness sensors designed for athletes to monitor their physiological metrics during workouts. Founded in 2012, Whoop provides a performance optimization system that continuously tracks key indicators such as heart rate, sleep, and recovery. The company's flagship product, the Whoop Strap 3.0, collects data around the clock, offering users insights that help balance training, minimize injuries, and enhance overall performance. In addition to the wearable device, Whoop offers a variety of apparel and accessories, including bands, tops, joggers, and hats, primarily sold online. By delivering personalized insights into physical exertion and recovery, Whoop aims to help athletes and teams maximize their potential and improve their training outcomes.

Replicated, Inc. is a company that specializes in providing tools for the deployment and management of third-party applications within enterprise environments. Founded in 2014 and headquartered in Culver City, California, Replicated offers a solution for organizations seeking to install and operate Software as a Service (SaaS) applications securely within their own firewalls. By enabling software vendors to deliver cloud-native applications in on-premises data centers or private clouds, Replicated enhances security and control for its clients. The company's offerings facilitate the management and support of these applications, ultimately simplifying the customer support process for businesses.

Wealthsimple Financial Inc. is a Toronto-based company that specializes in providing digital investment advisory services across Canada and operates additional offices in Brooklyn, New York, and London, United Kingdom. Founded in 2014, Wealthsimple offers a range of financial tools designed to help investors grow and manage their money. The company builds diversified portfolios of exchange-traded funds (ETFs) on behalf of its clients, offering accessible and affordable investment management without the high fees and account minimums typical of traditional firms. Wealthsimple also provides on-demand financial planning solutions and a hybrid savings and spending product known as Wealthsimple Cash. As of September 2020, Wealthsimple operates as a subsidiary of Purpose Advisor Solutions Inc.

Hexagon Bio, Inc. is a biotechnology company that specializes in discovering novel small molecule therapeutics by mining genomic data from fungal genomes. Founded in 2016 and headquartered in Menlo Park, California, Hexagon Bio leverages a proprietary platform that integrates data science, synthetic biology, and automation to identify and engineer drugs. The company's innovative approach focuses on developing targeted therapies for diseases with unmet medical needs by searching for evolutionarily refined molecules and their associated protein targets. Through its unique methodology, Hexagon Bio aims to uncover new medicines encoded within the global metagenome, ultimately striving to improve patient outcomes.

Recursion Pharmaceuticals, Inc. is a clinical-stage biotechnology company based in Salt Lake City, Utah, that focuses on revolutionizing drug discovery through the integration of advanced technologies such as artificial intelligence, automation, and bioinformatics. Founded in 2013, the company has developed a comprehensive drug discovery platform that includes various tools and software, such as ReChem for chemical compound design, ReScreen for managing complex experimental workflows, and RePredict for modeling drug relationships using machine learning. These innovations enable Recursion to generate extensive biological and chemical datasets, facilitating the exploration of foundational biology and accelerating the development of new therapeutic solutions. Through its unique approach, Recursion aims to significantly enhance patient outcomes and streamline the drug discovery process.

Boundless Immigration is a Seattle-based company founded in 2017 that focuses on simplifying the immigration process for individuals, families, and businesses. It offers an innovative platform that empowers users to navigate the complexities of the immigration system with confidence and ease. By providing expert legal guidance and personalized support, Boundless ensures that clients have access to the necessary tools and information for their immigration journey. The company's commitment to affordability and accessibility allows users to connect with immigration lawyers and file their applications online, streamlining what can often be a challenging experience.

Castor is an international health-tech company that provides a cloud-based clinical data platform designed to streamline the clinical trial process for researchers globally. Founded by CEO Derk Arts, MD, Ph.D., the platform is utilized by over 50,000 researchers in 90 countries, supporting more than 4,000 studies across diverse therapeutic areas, including diabetes, cardiovascular disease, rare diseases, infectious diseases, and oncology. Castor's platform facilitates the collection and analysis of extensive data from both traditional and remote trials, having reached significant milestones such as 180 million data points and 2 million enrolled patients. The company's mission is to make research data reusable, thereby enabling AI-driven clinical trials and enhancing the overall impact of data within the medical research community.

Odeko, Inc. is a software company that specializes in inventory and supply chain management solutions tailored for coffee retailers, including cafes and bakeries. Founded in 2019 and based in New York, Odeko’s platform provides tools for inventory tracking, order fulfillment, and customer engagement, helping small business owners streamline their operations. The software utilizes data analytics and artificial intelligence to analyze sales trends and create automated ordering models, which assist retailers in reducing waste and increasing sales. By integrating with various payment systems and delivery services, Odeko enhances the operational efficiency of its clients, enabling them to compete effectively in the market.

Brella Ltd., established in 2016 and based in Jyvaskyla, Finland, specializes in developing a mobile and web networking application. This platform facilitates connections among attendees at events, conferences, and live streams, utilizing a matchmaking algorithm to help professionals grow their business network and meet relevant individuals. Brella's primary goal is to streamline and enhance networking experiences, enabling users to find and engage with high-value contacts efficiently.

Ansel Health is a company that develops a health insurance platform designed to improve employee benefits for employers through a straightforward supplemental health benefits plan. The platform provides insurance services that offer financial support in the form of cash payments to individuals diagnosed with various covered conditions, including those related to COVID-19. This support aims to help mitigate the financial challenges associated with serious health issues, facilitating a smoother recovery process for affected individuals.

Scaling AI to the Real World.

Flatfile Inc. is a company that specializes in data onboarding solutions, enabling developers to efficiently validate, map, and import CSV data from various web applications. Founded in 2018 and based in Denver, Colorado, Flatfile offers a platform that integrates seamlessly with software applications, allowing users to upload data through formats such as CSV, XLS, or TSV. Its key products include Portal, which provides an import button embedded via a JavaScript snippet, and Concierge, which creates secure collaborative workspaces for organizations to manage complex data ingestion challenges. The platform is designed to enhance developer productivity, reduce costs, and improve data quality by learning to identify and clean incoming data over time. Numerous companies, including AstraZeneca and Square, utilize Flatfile’s API-first platform to streamline their data import processes.

Insitro, Inc. is a data-driven company focused on drug discovery and development, particularly targeting nonalcoholic steatohepatitis (NASH). Founded in 2018 by Daphne Koller and based in South San Francisco, California, Insitro harnesses machine learning and high-throughput biology to revolutionize the process of drug discovery. The company creates extensive functional genomic data sets and integrates them with patient data through innovative machine learning techniques. This approach allows Insitro to build predictive models that enhance target selection, streamline the design of therapeutics, and optimize drug development strategies. By addressing critical challenges in pharmaceutical research and development, Insitro aims to accelerate the delivery of new and effective treatments to patients.

Ansel Health is a company that develops a health insurance platform designed to improve employee benefits for employers through a straightforward supplemental health benefits plan. The platform provides insurance services that offer financial support in the form of cash payments to individuals diagnosed with various covered conditions, including those related to COVID-19. This support aims to help mitigate the financial challenges associated with serious health issues, facilitating a smoother recovery process for affected individuals.

Xilis, Inc. is a biotechnology company founded in 2019 and based in Chapel Hill, North Carolina. The company specializes in developing next-generation organoid technologies aimed at guiding precision therapy for cancer patients and enhancing drug discovery processes. Its flagship platform, XilisµO, facilitates rapid diagnostics, personalized drug screening, and the creation of scalable patient-derived models, which support high-throughput drug discovery. By enabling both physicians and pharmaceutical companies to conduct tailored drug screenings, Xilis aims to lower costs and improve treatment outcomes for cancer patients.

Comet ML Inc. is a New York-based company that provides a meta machine learning platform designed to assist data science teams and individuals in building reliable machine learning models for real-world applications. The platform enables users to automatically track datasets, code changes, experimentation history, and production models, thereby enhancing efficiency, transparency, and reproducibility in the machine learning process. By allowing data scientists to maintain their preferred workflows while effectively collaborating and tracking previous work, Comet facilitates a more organized approach to experimentation. Additionally, the platform incorporates bayesian hyperparameter optimization, which streamlines the model tuning process and reduces the time typically required for manual adjustments. This comprehensive solution increases visibility into data science efforts and improves the overall effectiveness of machine learning initiatives within organizations.