Two Sigma Ventures

Steadily operates an online insurance platform that specializes in providing landlord insurance tailored for short-term rental property managers. The platform allows landlords to easily secure property insurance coverage by pre-filling essential data points such as property size and year of construction, streamlining the process of obtaining quotes. Steadily's insurance offerings include protection against various potential damages, including those caused by weather, fire, water, vandalism, as well as liability coverage for guest injuries and lawsuits. This service complements Guesty's existing suite of tools designed to enhance communications, operations, growth, and financial management for property managers, thereby adding valuable resources to facilitate property management in the short-term rental market.

Tive is a Boston-based startup that provides companies with end-to-end visibility into their supply chains through a sensor-driven tracking platform. The company develops a solution that combines cellular-connected trackers with cloud-based software, allowing clients to monitor, visualize, and optimize their operations in real-time. Tive's platform offers customized alerts, reporting, and analysis for both inbound and outbound shipments across various transportation modes. By enhancing supply chain transparency, Tive helps businesses improve efficiency, reduce logistics costs, and minimize manufacturing disruptions, ultimately enabling them to meet regulatory requirements effectively.

Terray Therapeutics is a biotechnology company based in Pasadena, California, founded in 2018. The company specializes in developing innovative treatments for complex human diseases by integrating experimentation and computation to enhance small molecule drug discovery. Terray's unique platform employs ultra-dense microarray technology alongside artificial intelligence and synthetic chemistry to generate extensive and precise chemical datasets. This allows for a rapid design-make-test-analyze cycle, facilitating efficient exploration of chemical space and mapping biochemical interactions between small molecules and disease causes. By utilizing automation and machine learning, Terray addresses significant therapeutic challenges, ultimately guiding the next cycles of drug design and experimentation.

Distributional is a developer of an AI testing and evaluation platform focused on ensuring that artificial intelligence systems are safe, reliable, and secure. The company offers tools for continuous monitoring, which include generating test cases and analyzing results. These tools help organizations ensure that their AI systems perform as expected, thereby fostering trust in AI technologies. By providing these capabilities, Distributional enables customers to deploy AI products more frequently and effectively, allowing them to fully leverage the potential benefits of AI within their operations.

Arda Therapeutics is a biotechnology company founded in 2021 in the San Francisco Bay Area that focuses on addressing chronic diseases and aging by targeting and eliminating pathogenic cells responsible for these conditions. The company utilizes single-cell data to identify specific pathogenic cells and their markers, allowing for the development of precise therapies that exclusively eliminate these harmful cells. This targeted approach aims to eradicate the entire pathological network while preserving healthy cells, thereby enabling effective treatment without adverse effects on the patient's overall cellular health.

Crossover Markets Group operates a digital asset exchange specifically tailored to address the liquidity requirements of institutional clients. The company's platform is engineered to enhance the speed of cryptocurrency trading and minimize latency, aligning with the performance standards demanded by institutional investors in traditional foreign exchange and equity markets. By facilitating seamless cryptocurrency transactions, Crossover Markets aims to provide a reliable trading environment that supports the unique needs of its institutional clientele.

Vizzu is an intuitive, cinematic data storytelling tool that transforms complex data into memorable, engaging, animated stories. By seamlessly combining data analysis and visualization steps, Vizzu saves users valuable time while ensuring impactful data storytelling. Vizzu’s mission is to democratize data analysis and presentation, making it accessible and engaging for all.

Gameto is a biotechnology company focused on improving female reproductive health through innovative therapies. Recognizing that women's health is an underserved area with limited treatment options, Gameto aims to develop advanced solutions that enhance patient outcomes. The company utilizes cellular engineering to create female reproductive cell lines, employing proprietary combinations of transcription factors to reprogram human induced pluripotent stem cells (hiPSCs) into engineered ovarian and endometrial cell lines that function similarly to natural cells. This platform supports a portfolio of cellular therapeutics targeting various female reproductive diseases. Gameto's flagship program, Fertilo, is designed to enhance the processes of in vitro fertilization (IVF) and egg freezing, making them shorter, safer, and more effective. Additional applications of Gameto's technology include Deovo, an organoid of the female reproductive system, and Ameno, a cell-based therapeutic aimed at alleviating the health issues associated with primary ovarian insufficiency and menopause.

Xaira Therapeutics is an integrated biotechnology company focused on revolutionizing drug discovery and development through the application of artificial intelligence. Headquartered in the San Francisco Bay Area, Xaira combines expertise in machine learning, extensive biological and clinical data generation, and robust therapeutic product development. By harnessing advanced AI techniques, the company aims to enhance the understanding of biological processes and improve the effectiveness of therapies. Xaira's approach encompasses all stages of drug discovery, striving to transform how diseases are treated and enabling clients to deliver innovative therapeutic solutions.

Nullify is a cybersecurity platform that develops AI agents designed to autonomously handle application security tasks, mimicking the reasoning and decision-making capabilities of human security engineers. This innovation addresses the significant disparity between the number of software engineers and security engineers, which stands at 100 to 1, exacerbated by a growing shortage of cybersecurity professionals. By automating key aspects of product security work, such as testing, prioritization, remediation, and threat modeling, Nullify allows organizations to enhance their software security efficiently without the need to expand their security teams. The platform serves as a comprehensive solution that integrates various open-source security testing tools, executing them on entire codebases with a single command and producing a coherent output. This enables developers to create more secure software while allowing security teams to concentrate on more strategic security initiatives.

Treet operates a peer-to-peer resale marketplace designed to assist apparel brands in adopting circular economy practices and managing their secondhand market. By providing a platform where customers can buy and sell used items directly with one another, Treet creates additional revenue opportunities for brands while enhancing customer loyalty. The company oversees all logistics and support, allowing brands to focus on their core business while benefiting from the resale experience. This approach enables e-commerce brands to promote sustainability and take ownership of their secondhand sales, transforming used products into valuable offerings that feel new to consumers.

Anomalo is a developer of an artificial intelligence-based data validation tool that helps organizations continuously inspect and validate the data entering their warehouses. The company’s solution automatically detects and explains issues in enterprise data, facilitating a seamless connection to data warehouses. By employing automated machine learning technology, Anomalo enables companies to validate and document their data with minimal configuration, eliminating the need for users to write any code. This approach streamlines the data validation process, enhancing data integrity and reliability for enterprises.

Ansel Health is a developer of a health insurance platform designed for employers to improve employee benefits through a straightforward supplemental health benefits plan. The company provides insurance services that offer cash payouts to individuals diagnosed with various conditions, including those related to COVID-19. This support helps alleviate financial burdens associated with serious health issues, ensuring that employees have access to necessary resources for recovery.

Distributional is a developer of an AI testing and evaluation platform focused on ensuring that artificial intelligence systems are safe, reliable, and secure. The company offers tools for continuous monitoring, which include generating test cases and analyzing results. These tools help organizations ensure that their AI systems perform as expected, thereby fostering trust in AI technologies. By providing these capabilities, Distributional enables customers to deploy AI products more frequently and effectively, allowing them to fully leverage the potential benefits of AI within their operations.

Developer of artificial intelligence-driven solar cell technology platform designed to build next-generation cells. The company's platform technology offers perovskite silicon tandem solar cells that are optimized and improved based on data from those that came before and provides mainstream silicon technology that has a combination of materials and processes to reach its fundamental limits, enabling clients with new solar and semiconductor technologies in a fraction of the time and cost, compared to conventional methods.

Objective is a company that specializes in AI-driven search solutions for websites and applications. It has developed a low-code platform designed to create multi-search applications, allowing users to search through images, text, and video. By providing a simple SaaS API, Objective enables the integration of advanced search capabilities that utilize natural language processing and various data combinations, making it easier for developers to enhance user experiences in their applications.

Membrane Labs is a fintech firm that provides institutional digital asset services for OTC transactions.

Cerby, Inc., founded in 2020 and based in Alameda, California, specializes in cybersecurity tools that address the challenges of managing disconnected applications. The company offers a comprehensive access management platform that automates security tasks by leveraging identity providers, thereby eliminating the need for manual tools and compensating controls like enterprise password managers. Cerby's patent-pending access orchestration engine facilitates passwordless authentication for applications that do not support standard protocols such as SSO, SAML, or SCIM. By automating processes such as offboarding and two-factor authentication enrollment, Cerby enhances visibility and control for identity and access management professionals, ultimately reducing risks and costs while increasing organizational productivity.

Raincoat specializes in creating scalable embedded climate insurance products, supported by an automated infrastructure. The company collaborates with insurers, governments, and financial institutions to develop parametric insurance solutions that provide immediate payouts for catastrophe policies. By unlocking new markets, Raincoat enables businesses to achieve financial resilience against the impact of natural disasters, thus promoting climate resilience on a larger scale.

Building the hyperverse. We let people stream, make content, and make friends as an avatar.

Omni Network is a blockchain that supports applications in functioning across all rollups. The company creates technologies that support personal freedoms and enable global collaboration.

NetBox Labs specializes in simplifying the management of complex networks through its innovative cloud-based platform, NetBox Cloud. This enterprise-grade, software-as-a-service (SaaS) offering is built on open-source technology and aims to enhance network automation for operators. The platform features a central database that enables users to query data consistently and accurately, facilitating quick and efficient network automation. By providing a comprehensive suite of tools and expertise, NetBox Labs helps clients avoid manual errors and the complications associated with traditional spreadsheet methods, while enforcing both physical and logical rules within their networks.

Crossover Markets Group operates a digital asset exchange specifically tailored to address the liquidity requirements of institutional clients. The company's platform is engineered to enhance the speed of cryptocurrency trading and minimize latency, aligning with the performance standards demanded by institutional investors in traditional foreign exchange and equity markets. By facilitating seamless cryptocurrency transactions, Crossover Markets aims to provide a reliable trading environment that supports the unique needs of its institutional clientele.

C3 Exchange operates a self-custodial trading platform that facilitates the buying and selling of spot and derivative assets. The exchange combines the advantages of self-custody and decentralization with the performance and accessibility typically associated with traditional trading platforms. Its innovative clearing engine protocol allows for cross-margin and cross-collateralization, enabling traders to optimize their capital usage by calculating margin requirements across all open positions in their accounts. Through this approach, C3 Exchange aims to enhance the trading experience while maintaining user control over their assets.

Freeform is a 3D printing company that specializes in metal 3D printing solutions for manufacturing industries. The company focuses on deploying software-defined, self-sufficient metal 3D printing factories globally, effectively merging software scalability with physical production capabilities. Freeform's proprietary technology utilizes advanced sensing, real-time controls, and data-driven learning, enabling the production of digitally verified and flawless parts at unprecedented speeds and costs. This innovative approach allows manufacturers across various sectors to transition swiftly from concept to volume production, making the advantages of 3D printing accessible to a broader range of industries.

Crux Informatics Inc., founded in 2017 and headquartered in San Francisco, California, specializes in data processing and management services through its external data automation platform. This platform facilitates the integration, transformation, and observability of third-party data, effectively bridging the gap between data suppliers and consumers. Crux automates the development of data pipelines, ensures ongoing validation of data quality, and manages operations on a large scale across various cloud platforms. By leveraging advanced technology and a team of experienced data engineers, Crux enhances the efficiency of external data integration workflows, catering to the needs of companies seeking to optimize their data operations. The company has garnered support from prominent financial institutions, indicating its strong presence in the industry.

Osmo is a company that combines artificial intelligence with olfactory science to create a platform that gives computers a sense of smell. Initially focused on the fragrance industry, Osmo develops aroma molecules for products such as perfumes, shampoos, lotions, and candles. In addition to enhancing consumer experiences, the technology has the potential to detect diseases earlier and track pandemics, ultimately aiming to improve overall health and well-being. By addressing these challenges, Osmo seeks to revolutionize how scent is integrated into everyday life and its implications for human health.

Rive is a company focused on enhancing collaboration between designers and developers through its real-time animation platform. This platform allows for the creation of animated interactive experiences that are faster, smaller, and more memory-efficient than traditional design solutions. By enabling designers to produce interactive content from concept to production, Rive simplifies the workflow and reduces the need for complex handoffs between teams. The platform facilitates the design and animation of various graphics, including animated user interfaces, characters, and icons, making it easier for creative teams to iterate freely. Overall, Rive's innovative tools streamline the development of high-quality animation for applications and games, saving businesses both time and engineering resources.

Enveda Biosciences is a biotechnology company focused on drug discovery through the exploration of chemical diversity found in nature. Utilizing AI-powered tools, the company develops a robust database of chemical molecules derived from living organisms. Enveda's platform integrates machine learning, metabolomics, and robotics to analyze natural samples for their chemical structures and biological activities. This innovative approach allows for the efficient identification of potential new medicines, including antibiotics and hypotensives, without the need for isolating individual compounds or conducting extensive experiments. By harnessing nature's hidden chemistry, Enveda aims to accelerate the development of novel therapeutics for the healthcare industry.

Cajal Neuroscience is a biotechnology company focused on developing innovative therapies for neurodegenerative diseases. By integrating human genetics, functional genomics, and advanced microscopy, the company aims to identify novel therapeutic targets. Cajal utilizes a range of cutting-edge technologies, including high-throughput functional genomics and multi-omics approaches, to screen for targets that significantly influence the progression of neurodegenerative diseases. This comprehensive methodology supports the development of precision medicine, ultimately aiding healthcare professionals in treating patients affected by these conditions.

Hexagon Bio, Inc. is a biotechnology company based in Menlo Park, California, focused on discovering novel drugs for diseases that lack effective treatments. Established in 2016, the company utilizes a data-driven approach that combines genomics, synthetic biology, and computational techniques. By mining genomic data from fungal genomes, Hexagon Bio aims to identify targeted small molecule therapeutics. Its proprietary platform leverages data science to engineer drugs from DNA sequences, enabling the identification of small molecule inhibitors that interact with specific target proteins. This innovative method allows researchers to tap into the global metagenome, facilitating the development of new medicines aimed at improving patient outcomes.

Flatfile Inc. is a company that specializes in data onboarding solutions, enabling developers to efficiently validate, map, and import CSV data from various web applications. Founded in 2018 and based in Denver, Colorado, Flatfile offers a platform that integrates seamlessly with software applications, allowing users to upload data through formats such as CSV, XLS, or TSV. Its key products include Portal, which provides an import button embedded via a JavaScript snippet, and Concierge, which creates secure collaborative workspaces for organizations to manage complex data ingestion challenges. The platform is designed to enhance developer productivity, reduce costs, and improve data quality by learning to identify and clean incoming data over time. Numerous companies, including AstraZeneca and Square, utilize Flatfile’s API-first platform to streamline their data import processes.

Hivemind Technologies AG is a company based in Cologne, Germany, specializing in the development of social video platforms and mobile applications. It provides a range of application programming interface (API) solutions that facilitate topic identification, social metrics, polarity analysis, language detection, and news monitoring. The company offers tools for publishers, including analytics for tracking and comparing articles, news widgets to enhance websites with relevant feeds, and a dashboard for monitoring social news performance. Additionally, Hivemind Technologies delivers consulting services to assist clients in understanding data flows, selecting appropriate technology stacks, designing automated processes, and building data science teams. With a focus on machine learning and data analytics, the company aims to help businesses modernize their technology and effectively manage large volumes of data. Founded in 2011, Hivemind Technologies was formerly known as Alpha 12.

Xilis, Inc. is a biotechnology company based in Chapel Hill, North Carolina, founded in 2019. It specializes in developing advanced organoid technologies aimed at guiding precision therapy for cancer patients and enhancing drug discovery processes. The company's flagship platform, XilisµO, facilitates rapid diagnostics and personalized drug screening while providing scalable, patient-derived models for high-throughput drug discovery. This technology supports physicians and pharmaceutical companies in creating tailored treatments by enabling effective drug screening, ultimately contributing to more precise and cost-efficient cancer therapies.

Isabl is a startup focused on developing advanced diagnostic assays for cancer through whole-genome and RNA sequencing. Founded in 2020 after incubating its technology at Memorial Sloan Kettering Cancer Center from 2015 to 2019, Isabl participated in the Winter 2020 batch of Y Combinator and has raised $3 million in seed funding from investors including Two Sigma Ventures and BoxOne Ventures. In 2021, the company received the FDA Breakthrough Device designation, highlighting the innovative nature of its cancer diagnostic tests. Additionally, Isabl was awarded a $2 million direct-to-phase-2 SBIR grant from the National Cancer Institute to further the development of its specialized test, Isabl GxT, aimed at pediatric and rare solid tumors. The leadership team, comprising Dr. Elli Papaemmanuil, Dr. Andrew Kung, and Juan Medina, brings extensive expertise in precision medicine, computational biology, and software engineering, with a proven history in biomarker discovery and clinical decision support. Isabl's platform enhances the ability of oncology centers to analyze genomic data effectively and supports the creation of data-driven automation in cancer diagnosis.

Tive is a Boston-based startup that provides companies with end-to-end visibility into their supply chains through a sensor-driven tracking platform. The company develops a solution that combines cellular-connected trackers with cloud-based software, allowing clients to monitor, visualize, and optimize their operations in real-time. Tive's platform offers customized alerts, reporting, and analysis for both inbound and outbound shipments across various transportation modes. By enhancing supply chain transparency, Tive helps businesses improve efficiency, reduce logistics costs, and minimize manufacturing disruptions, ultimately enabling them to meet regulatory requirements effectively.

Remote is a global HR solutions provider that facilitates international hiring and payroll management for distributed teams. They offer a platform designed to help companies recruit top talent worldwide, ensuring compliance with local laws while streamlining project allocation and payments. This enables businesses to expand their workforce globally, enhancing productivity and employment opportunities.

Okteto Inc. is a software company that operates a cloud application development platform specifically designed for Kubernetes. Founded in 2018 and headquartered in San Francisco, California, Okteto provides a suite of tools that enable developers to easily access and manage Kubernetes infrastructure. Its offerings include Okteto Enterprise, which allows users to visualize workloads through a developer-friendly dashboard, apply security policies, and create secure namespaces. The platform facilitates the rapid deployment of applications, supports integration with the Okteto CLI, and ensures that sensitive credentials are securely managed. By allowing developers to instantly set up pre-configured environments in the cloud, Okteto aims to enhance the speed and efficiency of cloud-native application development.

Timescale is a data analysis platform specializing in time-series data, designed for the Internet of Things (IoT) and analytics applications. The company offers an open-source SQL database that integrates seamlessly with PostgreSQL, allowing developers to efficiently organize, store, and analyze large volumes of time-series and machine data. By implementing low-level distributed query optimizations within its database architecture, Timescale enhances performance and simplifies complex queries. The platform is aimed at software developers and businesses globally, providing them with the tools necessary to advance their computing capabilities. Timescale has attracted significant investment from prominent venture capital firms, contributing to its growth and the expansion of its global workforce.

Kallyope Inc. is a biotechnology company based in New York City that focuses on the gut-brain axis to develop innovative therapeutics and consumer products aimed at enhancing human health. Founded in 2014, Kallyope employs a multidisciplinary approach, integrating technologies such as sequencing, computational biology, neural imaging, and human genetics to deepen the understanding of gut-brain biology. This comprehensive understanding enables the company to create effective and well-tolerated oral medications targeting various health issues, including diabetes, obesity, gut disorders, inflammatory diseases, migraines, and allergies. With a team of experienced scientists and a strong foundation in drug discovery, Kallyope aims to address significant unmet medical needs through its research and development efforts.

Terray Therapeutics is a biotechnology company based in Pasadena, California, founded in 2018. The company specializes in developing innovative treatments for complex human diseases by integrating experimentation and computation to enhance small molecule drug discovery. Terray's unique platform employs ultra-dense microarray technology alongside artificial intelligence and synthetic chemistry to generate extensive and precise chemical datasets. This allows for a rapid design-make-test-analyze cycle, facilitating efficient exploration of chemical space and mapping biochemical interactions between small molecules and disease causes. By utilizing automation and machine learning, Terray addresses significant therapeutic challenges, ultimately guiding the next cycles of drug design and experimentation.

Radar provides a location data infrastructure platform designed for app developers to integrate location-based services into their applications. The platform facilitates the creation of personalized and contextually aware experiences through features such as geofencing, place detection, and location tracking. It supports a variety of use cases across sectors like retail, travel, and logistics, and offers tools for easy integration, including mobile SDKs and APIs. Radar's capabilities include detecting home, work, and traveling locations, as well as geocoding addresses into geographic coordinates. The company emphasizes privacy and security, ensuring responsible handling of location data. Founded in 2016, Radar continues to innovate with new APIs in private beta that enhance the functionality of its platform.

Rift Finance is a decentralized protocol focused on enhancing the growth of decentralized autonomous organizations (DAOs) through innovative incentive structures. The platform enables DAOs to deploy governance tokens from their treasuries, thereby increasing token liquidity while retaining ownership. This approach assists crypto companies in meeting their liquidity objectives, offering a means to generate attractive and safer returns for liquidity providers. By streamlining the process of token deployment, Rift Finance contributes to the overall efficiency and effectiveness of financial services in the Web3 ecosystem.

Figment Networks Inc. is a leading blockchain infrastructure and software provider based in Toronto, Canada, established in 2018. The company develops and operates an open-source crypto network, focusing on enhancing community engagement through tools that facilitate understanding of network health and performance for informed staking decisions. Figment supports various crypto networks, including Tezos, Cosmos, Livepeer, and Horizen. It offers a comprehensive suite of services, such as enterprise-grade node and staking infrastructure, the Hubble Web 3 explorer, and DataHub developer APIs, aimed at simplifying the use, development, and governance of blockchains for token holders and developers alike. Additionally, Figment publishes open-source software and economic research to further benefit the blockchain community.

Exai Bio is a next-generation liquid biopsy company that specializes in the early and accurate diagnosis of cancer. The company has developed a proprietary platform that analyzes cell-free RNA profiles, utilizing advanced artificial intelligence and machine learning algorithms. This technology focuses on orphan non-coding RNA and small RNA sequences that are prevalent in tumors but absent in normal tissue. By delivering clinical insights into cancer biology, Exai Bio's platform aids healthcare professionals in identifying cancer at its earliest stages and informs personalized treatment options for patients.

NewtonX, Inc. is a B2B market research company that connects professional services firms and financial institutions with verified business expertise. Founded in 2016 and based in New York, NewtonX utilizes an advanced algorithm known as the NewtonX Graph, which leverages artificial intelligence to recruit the ideal audience for specific business inquiries from a vast network of over 1.1 billion professionals across 140 industries. The company ensures that every professional is thoroughly verified, enabling clients to make informed decisions. NewtonX offers a range of services, including large-scale quantitative surveys, qualitative expert interviews, long-term consultations, and tailored research plans. Through its platform, NewtonX Prime, clients gain instant access to expert insights, enhancing their competitive advantage. The company collaborates with Fortune 500 companies, top consultancies, marketers, and investors, aiming to set a new standard for truth in B2B insights.

Comet is doing for ML what GitHub did for Code. It allows data scientists to automatically track their datasets, code changes, experimentation history, and production models creating efficiency, transparency, and reproducibility. Comet.ml is the first platform built for ML that enables engineers and data scientists to efficiently maintain their preferred workflow and tools, while easily tracking previous work and collaborating throughout the iterative process. Comet.ml also optimizes models with bayesian hyperparameter optimization - a type of algorithm - which saves time typically spent on manual tuning ML models. As a result, users have increased visibility of data science, ML results, and progress throughout an organization.

Facet is a computer software company that provides artists and engineers, aiming to redefine and humanize the creative process.

Socure Inc. is a provider of digital identity verification solutions, focusing on real-time identity authentication through its Socure ID+ platform. This predictive analytics platform utilizes artificial intelligence and machine learning to authenticate identities by analyzing a multitude of online and offline data sources, including email, phone numbers, addresses, IP addresses, and social media profiles. Socure's offerings include Aida, an AI-driven bot for validating digital identities, Docv, an omnichannel document verification solution, and Sigma Synthetic Fraud, which tackles synthetic identity fraud. The company addresses the needs of various sectors, including software, consulting, and financial firms, through compliance initiatives such as customer identification programs, know your customer requirements, and anti-money laundering measures. Founded in 2012 and headquartered in New York, Socure has established partnerships with key industry players to enhance its service delivery.

RightRev provides an automated revenue recognition solution that helps businesses manage financial reporting in compliance with current accounting standards. The platform integrates seamlessly with sales operations and revenue accounting processes, facilitating accurate tracking of revenue across various models, including subscriptions, one-time sales, and services. By enhancing existing customer relationship management and configure, price, quote tools, RightRev's solution offers a comprehensive approach to revenue reporting, ensuring transparency and reducing the risk of financial misstatements. The platform is designed to support finance professionals in navigating complex revenue accounting requirements, such as those outlined in ASC 606 and IFRS 15.

Anomalo is a developer of an artificial intelligence-based data validation tool that helps organizations continuously inspect and validate the data entering their warehouses. The company’s solution automatically detects and explains issues in enterprise data, facilitating a seamless connection to data warehouses. By employing automated machine learning technology, Anomalo enables companies to validate and document their data with minimal configuration, eliminating the need for users to write any code. This approach streamlines the data validation process, enhancing data integrity and reliability for enterprises.

Nelo is a financial technology company based in Mexico City, established on April 8, 2019. It specializes in developing a mobile application and a digital payment management platform that enables users to conduct financial transactions effectively. The platform allows individuals to send and request money easily, while also providing a free virtual card with no charges for account opening. This service facilitates real-time payment and balance tracking, empowering users to manage their funds in an affordable and secure manner.

Eclipse Advantage is a specialized warehouse labor management company that serves the foodservice and retail sectors in North America. Operating across 55 sites in the U.S. and Canada, it offers a range of services including in-bound receiving, pallet management, and order selection. By providing outsourced supply chain workforce solutions, Eclipse Advantage enhances productivity and delivers transparency in labor expenses for warehouses and distribution centers. The company is dedicated to high-quality service, guided by its core values of serving customers, ensuring safety, and achieving success.

Sora is a low-code intelligent workflow automation and data integration tool that connects different corporate applications such as HR, IT, and other systems and data sets to provide a smarter, more user-friendly experience for employees, business owners, and HR professionals.

Replicated, Inc. is a company that specializes in providing tools for the distribution and management of third-party applications within enterprise environments. Founded in 2014 and based in Culver City, California, Replicated addresses the needs of organizations seeking to deploy Software as a Service (SaaS) applications securely within their own firewalls. Its platform enables software vendors to deliver cloud-native applications that can be installed and managed in private data centers or private cloud environments. This approach enhances security and control for clients while simplifying customer support processes associated with on-premises software solutions.

Hexagon Bio, Inc. is a biotechnology company based in Menlo Park, California, focused on discovering novel drugs for diseases that lack effective treatments. Established in 2016, the company utilizes a data-driven approach that combines genomics, synthetic biology, and computational techniques. By mining genomic data from fungal genomes, Hexagon Bio aims to identify targeted small molecule therapeutics. Its proprietary platform leverages data science to engineer drugs from DNA sequences, enabling the identification of small molecule inhibitors that interact with specific target proteins. This innovative method allows researchers to tap into the global metagenome, facilitating the development of new medicines aimed at improving patient outcomes.

Castor is an international health-tech company that provides a cloud-based clinical data platform designed to streamline the clinical trial process for researchers globally. Founded by CEO Derk Arts, MD, Ph.D., the platform is utilized by over 50,000 researchers in 90 countries, supporting more than 4,000 studies across diverse therapeutic areas, including diabetes, cardiovascular disease, rare diseases, infectious diseases, and oncology. Castor's platform facilitates the collection and analysis of extensive data from both traditional and remote trials, having reached significant milestones such as 180 million data points and 2 million enrolled patients. The company's mission is to make research data reusable, thereby enabling AI-driven clinical trials and enhancing the overall impact of data within the medical research community.

Remote is a global HR solutions provider that facilitates international hiring and payroll management for distributed teams. They offer a platform designed to help companies recruit top talent worldwide, ensuring compliance with local laws while streamlining project allocation and payments. This enables businesses to expand their workforce globally, enhancing productivity and employment opportunities.

Xilis, Inc. is a biotechnology company based in Chapel Hill, North Carolina, founded in 2019. It specializes in developing advanced organoid technologies aimed at guiding precision therapy for cancer patients and enhancing drug discovery processes. The company's flagship platform, XilisµO, facilitates rapid diagnostics and personalized drug screening while providing scalable, patient-derived models for high-throughput drug discovery. This technology supports physicians and pharmaceutical companies in creating tailored treatments by enabling effective drug screening, ultimately contributing to more precise and cost-efficient cancer therapies.

Terray Therapeutics is a biotechnology company based in Pasadena, California, founded in 2018. The company specializes in developing innovative treatments for complex human diseases by integrating experimentation and computation to enhance small molecule drug discovery. Terray's unique platform employs ultra-dense microarray technology alongside artificial intelligence and synthetic chemistry to generate extensive and precise chemical datasets. This allows for a rapid design-make-test-analyze cycle, facilitating efficient exploration of chemical space and mapping biochemical interactions between small molecules and disease causes. By utilizing automation and machine learning, Terray addresses significant therapeutic challenges, ultimately guiding the next cycles of drug design and experimentation.

Enveda Biosciences is a biotechnology company focused on drug discovery through the exploration of chemical diversity found in nature. Utilizing AI-powered tools, the company develops a robust database of chemical molecules derived from living organisms. Enveda's platform integrates machine learning, metabolomics, and robotics to analyze natural samples for their chemical structures and biological activities. This innovative approach allows for the efficient identification of potential new medicines, including antibiotics and hypotensives, without the need for isolating individual compounds or conducting extensive experiments. By harnessing nature's hidden chemistry, Enveda aims to accelerate the development of novel therapeutics for the healthcare industry.

Formlogic is a provider of autonomous manufacturing technology focused on delivering precision components for the space and frontier industries. The company aims to revolutionize part production by addressing issues within the domestic supply chain. Its advanced technology enhances the capabilities of workers, allowing novices to achieve expert-level tolerances while increasing productivity for experienced operators. Formlogic offers rapid turnaround times, with production orders completed in weeks, and provides real-time order status updates. This approach enables industries to obtain custom machined components with close tolerances at scale, improving overall efficiency and customer experience.

Appia Bio is a biotechnology company dedicated to the research and development of allogeneic cell therapies that can be readily available for patients. The company focuses on creating engineered cell therapies for various medical conditions using its innovative ACUA technology platform. This platform utilizes the biology of lymphocyte development along with chimeric antigen receptor (CAR) and T-cell receptor (TCR) gene engineering to produce CAR-engineered invariant natural killer T (CAR-iNKT) cell subtypes derived from hematopoietic stem cells. By maturing and scaling healthy stem cells into these therapies, Appia Bio aims to provide safe and targeted cancer treatments, thereby enhancing accessibility to off-the-shelf cell therapies for physicians and patients alike.

Text Blaze is a productivity-focused platform that enables users to save and insert programmable text snippets across the web using keyboard shortcuts. This innovative tool not only allows for plain text snippets but also supports dynamic inputs from users and integrates seamlessly with other applications through no-code solutions. By offering customizable templates and collaboration features, Text Blaze aims to streamline workflows, reduce repetitive typing, and minimize errors. Its functionality fosters teamwork by allowing users to share snippets with colleagues, ultimately enhancing efficiency and maximizing productivity in various professional environments.

Timescale is a data analysis platform specializing in time-series data, designed for the Internet of Things (IoT) and analytics applications. The company offers an open-source SQL database that integrates seamlessly with PostgreSQL, allowing developers to efficiently organize, store, and analyze large volumes of time-series and machine data. By implementing low-level distributed query optimizations within its database architecture, Timescale enhances performance and simplifies complex queries. The platform is aimed at software developers and businesses globally, providing them with the tools necessary to advance their computing capabilities. Timescale has attracted significant investment from prominent venture capital firms, contributing to its growth and the expansion of its global workforce.

Wealthsimple Financial Inc. is a Toronto-based company that specializes in providing digital investment advisory services across Canada and operates additional offices in Brooklyn, New York, and London, United Kingdom. Founded in 2014, Wealthsimple offers a range of financial tools designed to help investors grow and manage their money. The company builds diversified portfolios of exchange-traded funds (ETFs) on behalf of its clients, offering accessible and affordable investment management without the high fees and account minimums typical of traditional firms. Wealthsimple also provides on-demand financial planning solutions and a hybrid savings and spending product known as Wealthsimple Cash. As of September 2020, Wealthsimple operates as a subsidiary of Purpose Advisor Solutions Inc.

Wholesale Supplies Plus, Inc. is an online retailer specializing in supplies for soapmaking and cosmetic production. Established in 1999 and headquartered in Independence, Ohio, the company provides a wide range of products, including cosmetic additives, pre-made bases, colorants, essential oils, flavor oils, fragrance oils, molds, containers, packaging, and various kits for projects. By offering these materials, Wholesale Supplies Plus enables customers to create personalized personal care products tailored to their specific needs.

Ansel Health is a developer of a health insurance platform designed for employers to improve employee benefits through a straightforward supplemental health benefits plan. The company provides insurance services that offer cash payouts to individuals diagnosed with various conditions, including those related to COVID-19. This support helps alleviate financial burdens associated with serious health issues, ensuring that employees have access to necessary resources for recovery.

Boundless Immigration is a Seattle-based company founded in 2017 that focuses on simplifying the immigration process for individuals, families, and businesses. It offers an innovative platform that empowers users to navigate the complexities of the immigration system with confidence and ease. By providing expert legal guidance and personalized support, Boundless ensures that clients have access to the necessary tools and information for their immigration journey. The company's commitment to affordability and accessibility allows users to connect with immigration lawyers and file their applications online, streamlining what can often be a challenging experience.

Per Diem offers a mobile application designed to assist local businesses in selling subscriptions online, akin to a personalized version of Amazon Prime. The platform equips restaurants with essential marketing and fulfillment tools, enabling them to establish a strong digital presence. Through the app, customers can place orders directly, track rewards, and receive notifications, which encourages more frequent patronage. This approach not only enhances customer engagement but also allows restaurants to generate recurring revenues through monthly and annual subscription models.

Facet is a computer software company that provides artists and engineers, aiming to redefine and humanize the creative process.

Comet is doing for ML what GitHub did for Code. It allows data scientists to automatically track their datasets, code changes, experimentation history, and production models creating efficiency, transparency, and reproducibility. Comet.ml is the first platform built for ML that enables engineers and data scientists to efficiently maintain their preferred workflow and tools, while easily tracking previous work and collaborating throughout the iterative process. Comet.ml also optimizes models with bayesian hyperparameter optimization - a type of algorithm - which saves time typically spent on manual tuning ML models. As a result, users have increased visibility of data science, ML results, and progress throughout an organization.

Tive is a Boston-based startup that provides companies with end-to-end visibility into their supply chains through a sensor-driven tracking platform. The company develops a solution that combines cellular-connected trackers with cloud-based software, allowing clients to monitor, visualize, and optimize their operations in real-time. Tive's platform offers customized alerts, reporting, and analysis for both inbound and outbound shipments across various transportation modes. By enhancing supply chain transparency, Tive helps businesses improve efficiency, reduce logistics costs, and minimize manufacturing disruptions, ultimately enabling them to meet regulatory requirements effectively.

Cylera, Inc. is a cybersecurity company focused on protecting healthcare organizations from cyber threats and malware. Founded in 2017 and headquartered in New York, Cylera offers a comprehensive platform that utilizes patented technology to provide unified cybersecurity solutions. Their software specializes in asset management, risk analysis, and threat detection, specifically designed for the healthcare Internet of Things (IoT) environment. By identifying all connected devices, analyzing vulnerabilities, and mitigating threats in real time, Cylera enables healthcare providers and other organizations to effectively manage risks and respond automatically to potential security incidents.

Socure Inc. is a provider of digital identity verification solutions, focusing on real-time identity authentication through its Socure ID+ platform. This predictive analytics platform utilizes artificial intelligence and machine learning to authenticate identities by analyzing a multitude of online and offline data sources, including email, phone numbers, addresses, IP addresses, and social media profiles. Socure's offerings include Aida, an AI-driven bot for validating digital identities, Docv, an omnichannel document verification solution, and Sigma Synthetic Fraud, which tackles synthetic identity fraud. The company addresses the needs of various sectors, including software, consulting, and financial firms, through compliance initiatives such as customer identification programs, know your customer requirements, and anti-money laundering measures. Founded in 2012 and headquartered in New York, Socure has established partnerships with key industry players to enhance its service delivery.

Insitro, Inc. is a data-driven company focused on drug discovery and development, particularly targeting nonalcoholic steatohepatitis (NASH). Founded in 2018 by Daphne Koller and based in South San Francisco, California, Insitro harnesses machine learning and high-throughput biology to revolutionize the process of drug discovery. The company creates extensive functional genomic data sets and integrates them with patient data through innovative machine learning techniques. This approach allows Insitro to build predictive models that enhance target selection, streamline the design of therapeutics, and optimize drug development strategies. By addressing critical challenges in pharmaceutical research and development, Insitro aims to accelerate the delivery of new and effective treatments to patients.

Flatfile Inc. is a company that specializes in data onboarding solutions, enabling developers to efficiently validate, map, and import CSV data from various web applications. Founded in 2018 and based in Denver, Colorado, Flatfile offers a platform that integrates seamlessly with software applications, allowing users to upload data through formats such as CSV, XLS, or TSV. Its key products include Portal, which provides an import button embedded via a JavaScript snippet, and Concierge, which creates secure collaborative workspaces for organizations to manage complex data ingestion challenges. The platform is designed to enhance developer productivity, reduce costs, and improve data quality by learning to identify and clean incoming data over time. Numerous companies, including AstraZeneca and Square, utilize Flatfile’s API-first platform to streamline their data import processes.

Penn Foster College, Penn Foster Career School, and Penn Foster High School are part of Penn Foster, Inc., a global leader in online education. For more than 118 years, Penn Foster has been providing accredited career-focused degree and vocational programs in the fields of allied health, business, technology, education, and select trades. Nationally and regionally accredited Penn Foster High School (www.PennFosterHighSchool.com) and Penn Foster Career School (www.pennfoster.edu) are headquartered in Scranton, PA, with regional offices in Montreal, Canada. Penn Foster College is headquartered in Scottsdale, Arizona.

UMA is a decentralized platform focused on financial contracts, aiming to provide global market access through innovative technology. It allows users to trade derivative products without reliance on a centralized authority, minimizing risk and eliminating single points of failure. By enabling customers to create customized financial products, UMA facilitates automatic enforcement and immediate settlement of agreements. The platform also features a unique oracle that records verifiable truths or data on a blockchain, enhancing the integrity of the financial contracts. This structure incentivizes participants to challenge and provide evidence against recorded claims, fostering a transparent and robust ecosystem for decentralized finance.

Smartfrog Group, also known as Smartfrog & Canary Holding Inc., is a pioneering company in the consumer Internet of Things (IoT) sector, with a presence in over 180 countries. Founded in 2015, Smartfrog introduced the first entirely consumer-focused IoT software-as-a-service (SaaS) product, offering an affordable do-it-yourself smart home security subscription service. The company expanded its operations to the United States in 2018 through the acquisition of Canary Connect, merging the two businesses and establishing its headquarters in New York City. With a robust portfolio protected by over 100 patents, Smartfrog operates a full-stack platform that supports data-driven businesses and provides SaaS solutions across various domains, including smart home security, smart locks, in-home delivery, and healthcare services. The company aims to make modern technologies accessible and secure for everyone, and it continues to grow through both organic initiatives and strategic mergers and acquisitions.

Tive is a Boston-based startup that provides companies with end-to-end visibility into their supply chains through a sensor-driven tracking platform. The company develops a solution that combines cellular-connected trackers with cloud-based software, allowing clients to monitor, visualize, and optimize their operations in real-time. Tive's platform offers customized alerts, reporting, and analysis for both inbound and outbound shipments across various transportation modes. By enhancing supply chain transparency, Tive helps businesses improve efficiency, reduce logistics costs, and minimize manufacturing disruptions, ultimately enabling them to meet regulatory requirements effectively.

Candu is a product experience platform designed for software teams aiming to enhance their applications' user interfaces. Founded in 2018 by Jonathan Anderson and Michele Riccardo Esposito, Candu allows teams to create personalized and effective onboarding experiences through its drag-and-drop editor, which requires no coding. The platform offers a comprehensive UI component library for building tailored experiences and includes an analytics suite that provides insights into user engagement and feature adoption. This enables businesses to continually refine their applications based on user behavior and feedback. Additionally, Candu supports the integration of in-product courses and training, allowing non-technical teams to embed learning experiences and measure their impact effectively.

Remote is a global HR solutions provider that facilitates international hiring and payroll management for distributed teams. They offer a platform designed to help companies recruit top talent worldwide, ensuring compliance with local laws while streamlining project allocation and payments. This enables businesses to expand their workforce globally, enhancing productivity and employment opportunities.

Whoop, Inc. is a Boston-based company that specializes in the development and sale of wearable fitness sensors designed for athletes to monitor their physiological metrics during workouts. Founded in 2012, Whoop provides a performance optimization system that continuously tracks key indicators such as heart rate, sleep, and recovery. The company's flagship product, the Whoop Strap 3.0, collects data around the clock, offering users insights that help balance training, minimize injuries, and enhance overall performance. In addition to the wearable device, Whoop offers a variety of apparel and accessories, including bands, tops, joggers, and hats, primarily sold online. By delivering personalized insights into physical exertion and recovery, Whoop aims to help athletes and teams maximize their potential and improve their training outcomes.

Replicated, Inc. is a company that specializes in providing tools for the distribution and management of third-party applications within enterprise environments. Founded in 2014 and based in Culver City, California, Replicated addresses the needs of organizations seeking to deploy Software as a Service (SaaS) applications securely within their own firewalls. Its platform enables software vendors to deliver cloud-native applications that can be installed and managed in private data centers or private cloud environments. This approach enhances security and control for clients while simplifying customer support processes associated with on-premises software solutions.

Wealthsimple Financial Inc. is a Toronto-based company that specializes in providing digital investment advisory services across Canada and operates additional offices in Brooklyn, New York, and London, United Kingdom. Founded in 2014, Wealthsimple offers a range of financial tools designed to help investors grow and manage their money. The company builds diversified portfolios of exchange-traded funds (ETFs) on behalf of its clients, offering accessible and affordable investment management without the high fees and account minimums typical of traditional firms. Wealthsimple also provides on-demand financial planning solutions and a hybrid savings and spending product known as Wealthsimple Cash. As of September 2020, Wealthsimple operates as a subsidiary of Purpose Advisor Solutions Inc.

Hexagon Bio, Inc. is a biotechnology company based in Menlo Park, California, focused on discovering novel drugs for diseases that lack effective treatments. Established in 2016, the company utilizes a data-driven approach that combines genomics, synthetic biology, and computational techniques. By mining genomic data from fungal genomes, Hexagon Bio aims to identify targeted small molecule therapeutics. Its proprietary platform leverages data science to engineer drugs from DNA sequences, enabling the identification of small molecule inhibitors that interact with specific target proteins. This innovative method allows researchers to tap into the global metagenome, facilitating the development of new medicines aimed at improving patient outcomes.

Recursion Pharmaceuticals, Inc. is a clinical-stage biotechnology company based in Salt Lake City, Utah, that focuses on revolutionizing drug discovery through the integration of advanced technologies such as artificial intelligence, automation, and bioinformatics. Founded in 2013, the company has developed a comprehensive drug discovery platform that includes various tools and software, such as ReChem for chemical compound design, ReScreen for managing complex experimental workflows, and RePredict for modeling drug relationships using machine learning. These innovations enable Recursion to generate extensive biological and chemical datasets, facilitating the exploration of foundational biology and accelerating the development of new therapeutic solutions. Through its unique approach, Recursion aims to significantly enhance patient outcomes and streamline the drug discovery process.

Boundless Immigration is a Seattle-based company founded in 2017 that focuses on simplifying the immigration process for individuals, families, and businesses. It offers an innovative platform that empowers users to navigate the complexities of the immigration system with confidence and ease. By providing expert legal guidance and personalized support, Boundless ensures that clients have access to the necessary tools and information for their immigration journey. The company's commitment to affordability and accessibility allows users to connect with immigration lawyers and file their applications online, streamlining what can often be a challenging experience.

Castor is an international health-tech company that provides a cloud-based clinical data platform designed to streamline the clinical trial process for researchers globally. Founded by CEO Derk Arts, MD, Ph.D., the platform is utilized by over 50,000 researchers in 90 countries, supporting more than 4,000 studies across diverse therapeutic areas, including diabetes, cardiovascular disease, rare diseases, infectious diseases, and oncology. Castor's platform facilitates the collection and analysis of extensive data from both traditional and remote trials, having reached significant milestones such as 180 million data points and 2 million enrolled patients. The company's mission is to make research data reusable, thereby enabling AI-driven clinical trials and enhancing the overall impact of data within the medical research community.

Odeko, Inc. is a software company that specializes in inventory and supply chain management solutions tailored for coffee retailers, including cafes and bakeries. Founded in 2019 and based in New York, Odeko’s platform provides tools for inventory tracking, order fulfillment, and customer engagement, helping small business owners streamline their operations. The software utilizes data analytics and artificial intelligence to analyze sales trends and create automated ordering models, which assist retailers in reducing waste and increasing sales. By integrating with various payment systems and delivery services, Odeko enhances the operational efficiency of its clients, enabling them to compete effectively in the market.

Brella is a childcare center based in Los Angeles, California, that offers a flexible and fully licensed childcare service. Founded in 2017 by Darien Williams and Melanie Wolff, Brella focuses on providing a play-based program for infants to preschool-aged children. The center features an enrichment-based curriculum and age-appropriate classrooms, ensuring high caregiver-child ratios for quality care. Brella's innovative platform allows parents to select childcare packages priced by the hour, eliminating the need for long-term contracts. Additionally, the center provides optional on-site amenities such as workspaces and curated classes, aiming to create a stress-free environment for parents while ensuring their children receive excellent care and education.

Ansel Health is a developer of a health insurance platform designed for employers to improve employee benefits through a straightforward supplemental health benefits plan. The company provides insurance services that offer cash payouts to individuals diagnosed with various conditions, including those related to COVID-19. This support helps alleviate financial burdens associated with serious health issues, ensuring that employees have access to necessary resources for recovery.

Scaling AI to the Real World.

Flatfile Inc. is a company that specializes in data onboarding solutions, enabling developers to efficiently validate, map, and import CSV data from various web applications. Founded in 2018 and based in Denver, Colorado, Flatfile offers a platform that integrates seamlessly with software applications, allowing users to upload data through formats such as CSV, XLS, or TSV. Its key products include Portal, which provides an import button embedded via a JavaScript snippet, and Concierge, which creates secure collaborative workspaces for organizations to manage complex data ingestion challenges. The platform is designed to enhance developer productivity, reduce costs, and improve data quality by learning to identify and clean incoming data over time. Numerous companies, including AstraZeneca and Square, utilize Flatfile’s API-first platform to streamline their data import processes.

Insitro, Inc. is a data-driven company focused on drug discovery and development, particularly targeting nonalcoholic steatohepatitis (NASH). Founded in 2018 by Daphne Koller and based in South San Francisco, California, Insitro harnesses machine learning and high-throughput biology to revolutionize the process of drug discovery. The company creates extensive functional genomic data sets and integrates them with patient data through innovative machine learning techniques. This approach allows Insitro to build predictive models that enhance target selection, streamline the design of therapeutics, and optimize drug development strategies. By addressing critical challenges in pharmaceutical research and development, Insitro aims to accelerate the delivery of new and effective treatments to patients.

Ansel Health is a developer of a health insurance platform designed for employers to improve employee benefits through a straightforward supplemental health benefits plan. The company provides insurance services that offer cash payouts to individuals diagnosed with various conditions, including those related to COVID-19. This support helps alleviate financial burdens associated with serious health issues, ensuring that employees have access to necessary resources for recovery.

Xilis, Inc. is a biotechnology company based in Chapel Hill, North Carolina, founded in 2019. It specializes in developing advanced organoid technologies aimed at guiding precision therapy for cancer patients and enhancing drug discovery processes. The company's flagship platform, XilisµO, facilitates rapid diagnostics and personalized drug screening while providing scalable, patient-derived models for high-throughput drug discovery. This technology supports physicians and pharmaceutical companies in creating tailored treatments by enabling effective drug screening, ultimately contributing to more precise and cost-efficient cancer therapies.

Comet is doing for ML what GitHub did for Code. It allows data scientists to automatically track their datasets, code changes, experimentation history, and production models creating efficiency, transparency, and reproducibility. Comet.ml is the first platform built for ML that enables engineers and data scientists to efficiently maintain their preferred workflow and tools, while easily tracking previous work and collaborating throughout the iterative process. Comet.ml also optimizes models with bayesian hyperparameter optimization - a type of algorithm - which saves time typically spent on manual tuning ML models. As a result, users have increased visibility of data science, ML results, and progress throughout an organization.