Longwall Venture

Longwall Venture Partners is an Oxford-based venture capital firm founded in 2011, specializing in growth capital, early stage, and start-up investments in the science, healthcare, and technology sectors in the United Kingdom. They focus on investing in a variety of industries including physical science, life science, security, media, business software, and engineering.

Jane Burgoyne

Partner & Chief Financial Officer

David Denny

Partner

Matthew Frohn Ph.D

Partner

Michael Penington Ph.D

Partner

Kate Ronayne

Investment Director

53 past transactions

OrganOx

Series B in 2011
OrganOx Limited develops device known as Metra to store livers outside the body at normal body temperature. It engages in the research and study for test and transplant of livers. The company’s products are used to preserve the livers before transplantations. OrganOx Limited was incorporated in 2008 and is based in the Oxford, United Kingdom.

Verdel Instruments

Private Placement in 2019
Verdel Instruments Ltd develops two dimensional mass spectrometry (2DMS) equipment for structural analysis and sequencing equipment. The company provides mass spectrometry technology based equipment used in analytical laboratories to identify key components and impurities in biopharmaceuticals, food, chemical products, and the environment. It allows the researchers to get structural information from mixtures of components. Verdel Instruments Ltd was incorporated in 2018 and is based in Coventry, United Kingdom.

Closed Loop Medicine

Series A in 2021
Closed Loop Medicine (CLM) is a new breed of therapeutics company focused on care pathways, outcomes and the provision of dynamic personalised regimens. The company combines proven drugs with proprietary digital therapeutics enabling the digitisation and data capture of an entire care continuum. CLM has a pipeline of regimes in development that integrate Digital + Drug + Device for the treatment of some of the biggest challenges facing 21st century health systems - sleep disorders, hypertension, chronic pain and diabetes.

Closed Loop Medicine

Private Placement in 2019
Closed Loop Medicine (CLM) is a new breed of therapeutics company focused on care pathways, outcomes and the provision of dynamic personalised regimens. The company combines proven drugs with proprietary digital therapeutics enabling the digitisation and data capture of an entire care continuum. CLM has a pipeline of regimes in development that integrate Digital + Drug + Device for the treatment of some of the biggest challenges facing 21st century health systems - sleep disorders, hypertension, chronic pain and diabetes.

Kinomica

Private Placement in 2020
Kinomica Limited operates as a medicine research and diagnostics company. The company develops KScan, a biomarker and molecular diagnostics platform developed for treating cancer patients and other conditions. It helps to measures intracellular kinase and cell-signalling pathway activity in cells and tissues. Kinomica Limited was formerly known as Pronostics Ltd. and changed its name to Kinomica Limited in May 2017. Kinomica Limited was incorporated in 2016 and is based in Macclesfield, United Kingdom.

MIRICO

Private Placement in 2018
MIRICO Ltd. is a UK-based laser spectroscopy instrumentation company formed in 2015 as a spin-out from the Science and Technology Facilities Council. The technology underpinning MIRICO was developed by the RAL Space Laser Spectroscopy Team, led by Dr. Damien Weidmann. The laser spectroscopy team consists of 8 senior scientists who carry out cutting edge research and development. Over the years they have developed a range of spectroscopy techniques that overcome the major downfalls of current technologies. The company was formed to commercialise and take these technologies to market.

MIRICO

Venture Round in 2018
MIRICO Ltd. is a UK-based laser spectroscopy instrumentation company formed in 2015 as a spin-out from the Science and Technology Facilities Council. The technology underpinning MIRICO was developed by the RAL Space Laser Spectroscopy Team, led by Dr. Damien Weidmann. The laser spectroscopy team consists of 8 senior scientists who carry out cutting edge research and development. Over the years they have developed a range of spectroscopy techniques that overcome the major downfalls of current technologies. The company was formed to commercialise and take these technologies to market.

Azellon Limited

Venture Round in 2015
Azellon Limited develops and commercializes a platform technology using mesenchymal stem cells infused into a biological scaffold for tissue repair. The company offers Cell Bandage, a tissue repair technology that is used in the repair of tears of the avascular (white) zone knee meniscus. Its technology combines one’s own bone marrow stem cells with a special membrane that helps to deliver the cells into the injured site. Azellon Limited was incorporated in 2007 and is based in London, United Kingdom.

Arquer Diagnostics

Series B in 2017
Arquer Diagnostics Ltd. is engaged in the design, development, and commercialization of a non-invasive immunoassay diagnostic test for bladder and prostate cancer. It offers ELISA (enzyme-linked immunosorbent assay), a laboratory test for measuring small amounts of a substance in body fluids; and CE-marked an ELISA kit for Mcm5 for use in hospital path lavatories. The company also provides point of care system that comprises a robust reader instrument and disposable cartridges. It offers its ELISA and point-of-care urine tests for cancer for use in urology clinic, hospital laboratory, and the GP’s surgery. Arquer Diagnostics Ltd. was formerly known as UroSens Ltd. and changed its name to Arquer Diagnostics Ltd. in July 2015. The company was incorporated in 2005 and is based in Sunderland, United Kingdom.

Oxford PV

Series B in 2013
Oxford Photovoltaics Limited develops and commercializes thin-film perovskite solar cells that are printed directly onto silicon solar cells, CIGS solar cells, or glass. Oxford Photovoltaics Limited has a strategic partnership with Meyer Burger Technology Ltd. The company was incorporated in 2010 and is based in Oxford, United Kingdom.

Closed Loop Medicine

Seed Round in 2018
Closed Loop Medicine (CLM) is a new breed of therapeutics company focused on care pathways, outcomes and the provision of dynamic personalised regimens. The company combines proven drugs with proprietary digital therapeutics enabling the digitisation and data capture of an entire care continuum. CLM has a pipeline of regimes in development that integrate Digital + Drug + Device for the treatment of some of the biggest challenges facing 21st century health systems - sleep disorders, hypertension, chronic pain and diabetes.

Keit

Venture Round in 2016
Keit’s microFTS® design is a Fourier Transform Infrared (FTIR) spectrometer that is smaller, lighter and more rugged than any current system. Able to perform in extreme environments, the microFTS® was originally designed for space applications where these attributes are paramount. The microFTS® offers a new gold standard for real-time liquid-state analyses in the Pharmaceutical, Chemical, Oil & Gas, and Food & Beverage industries.

Biofidelity Ltd.

Private Placement in 2020
Biofidelity Ltd. engages in the research of molecular diagnostic assays for the detection of target DNA sequences. The assay developed by the company focuses on oncology, pre-natal testing, infectious disease, and organ transplant monitoring. The company was founded in 2019 and is headquartered in Cambridge, United Kingdom.

MIRICO

Seed Round in 2016
MIRICO Ltd. is a UK-based laser spectroscopy instrumentation company formed in 2015 as a spin-out from the Science and Technology Facilities Council. The technology underpinning MIRICO was developed by the RAL Space Laser Spectroscopy Team, led by Dr. Damien Weidmann. The laser spectroscopy team consists of 8 senior scientists who carry out cutting edge research and development. Over the years they have developed a range of spectroscopy techniques that overcome the major downfalls of current technologies. The company was formed to commercialise and take these technologies to market.

Verdel Instruments

Seed Round in 2019
Verdel Instruments Ltd develops two dimensional mass spectrometry (2DMS) equipment for structural analysis and sequencing equipment. The company provides mass spectrometry technology based equipment used in analytical laboratories to identify key components and impurities in biopharmaceuticals, food, chemical products, and the environment. It allows the researchers to get structural information from mixtures of components. Verdel Instruments Ltd was incorporated in 2018 and is based in Coventry, United Kingdom.

Closed Loop Medicine

Seed Round in 2019
Closed Loop Medicine (CLM) is a new breed of therapeutics company focused on care pathways, outcomes and the provision of dynamic personalised regimens. The company combines proven drugs with proprietary digital therapeutics enabling the digitisation and data capture of an entire care continuum. CLM has a pipeline of regimes in development that integrate Digital + Drug + Device for the treatment of some of the biggest challenges facing 21st century health systems - sleep disorders, hypertension, chronic pain and diabetes.

Caristo Diagnostics

Private Placement in 2018
Caristo Diagnostics Limited offers a artificial intelligence based software for measuring coronary artery inflammation and predict heart attacks. The company develops Cardiac Computed Tomography Angiography (CCTA) which enables measuring Fat Attenuation Index (FAI) during routine heart check ups. Caristo Diagnostics Limited was incorporated in 2018 and is based in Oxford, United Kingdom.

Lightcast Discovery

Series B in 2023
Lightcast uses a microfluidic platform to make advances towards unique clinical approaches, new therapies, and innovative products. The company's mission is to push the boundaries of complex cell analysis. Using the Lightcast platform, the company is working with major pharmaceutical companies and leading academic institutes to enable them to discover more. The Lightcast platform allows precise and highly flexible independent control of thousands of droplets. By combining droplets containing different cells, reporters or other reagents we can perform complex workflows without the need to manipulate cells by hand. Lightcast Discovery was founded in 2019 by Cameron Frayling.

Wayland Additive

Series B in 2023
Wayland Additive develops, manufactures, and distributes metal additive manufacturing 3D printing machines. The company provides scanning electron microscope and electron beam lithography. The company serves aerospace and medical industries. The company was founded in 2019 and is headquartered in Huddersfield, United Kingdom.

MicrofluidX

Seed Round in 2022
MicrofluidX Ltd develops a cell bioprocessing platform for autologous cell and gene therapy manufacturing. The company provides a microfluidic bioprocessing system that combines multiple cell culture capabilities, such as seeding, expansion, differentiation, transduction, washing, sorting, concentration, sampling, and harvesting in one closed system. Its automated and closed technology allows biologists to carry out process development by running dozens of cell culture conditions. The company was incorporated in 2018 and is based in London, United Kingdom.

Caristo Diagnostics

Series A in 2023
Caristo Diagnostics Limited offers a artificial intelligence based software for measuring coronary artery inflammation and predict heart attacks. The company develops Cardiac Computed Tomography Angiography (CCTA) which enables measuring Fat Attenuation Index (FAI) during routine heart check ups. Caristo Diagnostics Limited was incorporated in 2018 and is based in Oxford, United Kingdom.

Closed Loop Medicine

Private Placement in 2020
Closed Loop Medicine (CLM) is a new breed of therapeutics company focused on care pathways, outcomes and the provision of dynamic personalised regimens. The company combines proven drugs with proprietary digital therapeutics enabling the digitisation and data capture of an entire care continuum. CLM has a pipeline of regimes in development that integrate Digital + Drug + Device for the treatment of some of the biggest challenges facing 21st century health systems - sleep disorders, hypertension, chronic pain and diabetes.

Closed Loop Medicine

Grant in 2019
Closed Loop Medicine (CLM) is a new breed of therapeutics company focused on care pathways, outcomes and the provision of dynamic personalised regimens. The company combines proven drugs with proprietary digital therapeutics enabling the digitisation and data capture of an entire care continuum. CLM has a pipeline of regimes in development that integrate Digital + Drug + Device for the treatment of some of the biggest challenges facing 21st century health systems - sleep disorders, hypertension, chronic pain and diabetes.

Arquer Diagnostics

Venture Round in 2015
Arquer Diagnostics Ltd. is engaged in the design, development, and commercialization of a non-invasive immunoassay diagnostic test for bladder and prostate cancer. It offers ELISA (enzyme-linked immunosorbent assay), a laboratory test for measuring small amounts of a substance in body fluids; and CE-marked an ELISA kit for Mcm5 for use in hospital path lavatories. The company also provides point of care system that comprises a robust reader instrument and disposable cartridges. It offers its ELISA and point-of-care urine tests for cancer for use in urology clinic, hospital laboratory, and the GP’s surgery. Arquer Diagnostics Ltd. was formerly known as UroSens Ltd. and changed its name to Arquer Diagnostics Ltd. in July 2015. The company was incorporated in 2005 and is based in Sunderland, United Kingdom.

MIRICO

Funding Round in 2022
MIRICO Ltd. is a UK-based laser spectroscopy instrumentation company formed in 2015 as a spin-out from the Science and Technology Facilities Council. The technology underpinning MIRICO was developed by the RAL Space Laser Spectroscopy Team, led by Dr. Damien Weidmann. The laser spectroscopy team consists of 8 senior scientists who carry out cutting edge research and development. Over the years they have developed a range of spectroscopy techniques that overcome the major downfalls of current technologies. The company was formed to commercialise and take these technologies to market.

Momentum Bioscience

Series A in 2014
Momentum Bioscience Ltd develops rapid tests for critically-important clinical specimens. It provides ETGA, which provides ultrasensitive, rapid, and universal detection of all bacterial and fungal species and it only detects viable organisms. The company serves neonatal care, emergency care, and critical care applications. Momentum Bioscience Ltd was incorporated in 2005 and is based in Cardiff, United Kingdom.

Caristo Diagnostics

Venture Round in 2021
Caristo Diagnostics Limited offers a artificial intelligence based software for measuring coronary artery inflammation and predict heart attacks. The company develops Cardiac Computed Tomography Angiography (CCTA) which enables measuring Fat Attenuation Index (FAI) during routine heart check ups. Caristo Diagnostics Limited was incorporated in 2018 and is based in Oxford, United Kingdom.

Caristo Diagnostics

Seed Round in 2018
Caristo Diagnostics Limited offers a artificial intelligence based software for measuring coronary artery inflammation and predict heart attacks. The company develops Cardiac Computed Tomography Angiography (CCTA) which enables measuring Fat Attenuation Index (FAI) during routine heart check ups. Caristo Diagnostics Limited was incorporated in 2018 and is based in Oxford, United Kingdom.

Crysalin

Series A in 2011
Crysalin Limited engages in the research and development of crysalin lattice technology for determining protein structures. Its portfolio includes crysalins, a protein-based nanotechnology for application in protein structure determination, as well as biosensor development and optoelectronics. The company was founded in 2007 and is based in London, United Kingdom.

OxSonics Limited

Series B in 2017
OxSonics Limited develops and commercializes SonoTran, an oncological drug delivery platform and injectable sono-sensitive particles. Its SonoTran drug delivery platform delivers drugs throughout tumours, including to the areas that lie furthest from blood vessels. The company also develops a pipeline of therapies for the treatment of solid tumours, mCRC, and pancreatic ductal adenocarcinoma. OxSonics Limited was founded in 2013 and is based in Oxford, United Kingdom.

Oxford Space Systems

Private Placement in 2018
Oxford Space Systems Limited develops, manufactures, and markets deployable hardware structures for space environments in Europe and internationally. The company develops deployable panels/hinge systems, composite linear boom systems, and deployable antennas. Oxford Space Systems Limited was incorporated in 2013 and is based in Harwell, United Kingdom.

Base4

Venture Round in 2017
Base4 is focused on the innovation and development of state-of-the-art technologies for single-molecule analysis. We are developing cutting-edge, high-value technologies with demonstrable technical and commercial feasibility while building a valuable portfolio of IP and know-how.

LettUs Grow

Seed Round in 2020
LETTUS GROW LTD. provides irrigation and control technology. The company offers aeroponic hardware which helps in growing plants without soil and roots are watered using a fine mist and a LED light bulb enables the plant to photosynthesis and store energy; software and data services which optimise farm to reduce unnecessary labour and conditions for individual plant species. LETTUS GROW LTD. was founded in 2015 and is based in Bristol, United Kingdom.

Wayland Additive

Private Placement in 2019
Wayland Additive develops, manufactures, and distributes metal additive manufacturing 3D printing machines. The company provides scanning electron microscope and electron beam lithography. The company serves aerospace and medical industries. The company was founded in 2019 and is headquartered in Huddersfield, United Kingdom.

Biofidelity Ltd.

Private Placement in 2019
Biofidelity Ltd. engages in the research of molecular diagnostic assays for the detection of target DNA sequences. The assay developed by the company focuses on oncology, pre-natal testing, infectious disease, and organ transplant monitoring. The company was founded in 2019 and is headquartered in Cambridge, United Kingdom.

Sensiia

Venture Round in 2014
Sensiia Limited manufactures a sensor-based fertility wearable device. It also develops mobile application. The company’s fertility wearable, DuoFertility, tracks and predicts female ovulation cycles and help interpret the data from the application. Sensiia Limited was formerly known as Cambridge Temperature Concepts Limited and changed its name to Sensiia Limited in April, 2017. The company was founded in 2006 and is based in Cambridge, United Kingdom.

MicrofluidX

Seed Round in 2020
MicrofluidX Ltd develops a cell bioprocessing platform for autologous cell and gene therapy manufacturing. The company provides a microfluidic bioprocessing system that combines multiple cell culture capabilities, such as seeding, expansion, differentiation, transduction, washing, sorting, concentration, sampling, and harvesting in one closed system. Its automated and closed technology allows biologists to carry out process development by running dozens of cell culture conditions. The company was incorporated in 2018 and is based in London, United Kingdom.

Oxford HighQ

Private Placement in 2018
Oxford HighQ Ltd. manufactures sensor elements that are micrometers in size and highly parallelizable. The company offers technology that provides measurement of nanoparticle volume, aspect ratio and refractive index; Detection of chemicals in much smaller quantities; and Measurement using only minute liquid sample volumes. Oxford HighQ Ltd was founded in 2017 and is headquartered in Begbroke, United Kingdom.

Kinomica

Venture Round in 2020
Kinomica Limited operates as a medicine research and diagnostics company. The company develops KScan, a biomarker and molecular diagnostics platform developed for treating cancer patients and other conditions. It helps to measures intracellular kinase and cell-signalling pathway activity in cells and tissues. Kinomica Limited was formerly known as Pronostics Ltd. and changed its name to Kinomica Limited in May 2017. Kinomica Limited was incorporated in 2016 and is based in Macclesfield, United Kingdom.

User Replay

Series B in 2016
User Replay Limited develops digital customer experience analytics software solutions. It offers an integrated customer experience platform with machine learning to discover, inspect, and take action on the right sessions; and Active CX, a platform for recording and analysis of digital customer interaction. It serves financial services, insurance, retail, and travel markets in the United States, the United Kingdom, continental Europe, and internationally. The company was founded in 2009 and is based in Reading, United Kingdom. It has operations in Europe, the Middle East, Africa, and internationally.

Oxford Space Systems

Venture Round in 2018
Oxford Space Systems Limited develops, manufactures, and markets deployable hardware structures for space environments in Europe and internationally. The company develops deployable panels/hinge systems, composite linear boom systems, and deployable antennas. Oxford Space Systems Limited was incorporated in 2013 and is based in Harwell, United Kingdom.

Closed Loop Medicine

Private Placement in 2018
Closed Loop Medicine (CLM) is a new breed of therapeutics company focused on care pathways, outcomes and the provision of dynamic personalised regimens. The company combines proven drugs with proprietary digital therapeutics enabling the digitisation and data capture of an entire care continuum. CLM has a pipeline of regimes in development that integrate Digital + Drug + Device for the treatment of some of the biggest challenges facing 21st century health systems - sleep disorders, hypertension, chronic pain and diabetes.

Diamond Microwave Devices

Venture Round in 2009
Diamond Microwave Devices Ltd. engages in the development of semiconductor devices based on CVD diamond. Its devices are used in civil and defense systems for microwave power amplifier and transmitter applications. The company was founded in 2006 and is based in Leeds, the United Kingdom. Diamond Microwave Devices Ltd. operates as a subsidiary of Element Six (Pty) Ltd.

Oxford Cancer Biomarkers

Venture Round in 2015
Oxford Cancer Biomarkers is developing and commercializing a suite of colorectal cancer biomarker tests to improve the current treatment pathway. Oxford Cancer Biomarkers is closely affiliated with Institute of Cancer Medicine at Oxford University, where its founders lead translational cancer science research groups. Oxford Cancer Biomarkers has also partnered with pharmaceutical companies to use its discovery platforms CancerNav® and ToxNavTM to develop companion diagnostic tests for pipeline drugs.

Wayland Additive

Series A in 2024
Wayland Additive develops, manufactures, and distributes metal additive manufacturing 3D printing machines. The company provides scanning electron microscope and electron beam lithography. The company serves aerospace and medical industries. The company was founded in 2019 and is headquartered in Huddersfield, United Kingdom.

Biofidelity

Venture Round in 2024
Biofidelity developed a revolutionary molecular diagnostic assay that enables the rapid detection of target DNA sequences. Biofidelity’s mission is to improve and extend patients’ lives by enabling early detection of disease and better targeting of treatments with applications spanning oncology, prenatal testing, infectious disease, and organ transplant monitoring. Biofidelity was founded in 2019 and is headquartered of Cambridge, England.

Wayland Additive

Series A in 2021
Wayland Additive develops, manufactures, and distributes metal additive manufacturing 3D printing machines. The company provides scanning electron microscope and electron beam lithography. The company serves aerospace and medical industries. The company was founded in 2019 and is headquartered in Huddersfield, United Kingdom.

Wayland Additive

Series A in 2019
Wayland Additive develops, manufactures, and distributes metal additive manufacturing 3D printing machines. The company provides scanning electron microscope and electron beam lithography. The company serves aerospace and medical industries. The company was founded in 2019 and is headquartered in Huddersfield, United Kingdom.

MicrofluidX

Private Placement in 2020
MicrofluidX Ltd develops a cell bioprocessing platform for autologous cell and gene therapy manufacturing. The company provides a microfluidic bioprocessing system that combines multiple cell culture capabilities, such as seeding, expansion, differentiation, transduction, washing, sorting, concentration, sampling, and harvesting in one closed system. Its automated and closed technology allows biologists to carry out process development by running dozens of cell culture conditions. The company was incorporated in 2018 and is based in London, United Kingdom.