Caristo Diagnostics Limited, based in Oxford, United Kingdom, specializes in artificial intelligence-driven software for cardiovascular diagnostics. Founded in 2018, the company focuses on improving heart health assessments through its advanced imaging technology. By developing tools that analyze Cardiac Computed Tomography Angiography (CCTA), Caristo enables the measurement of Fat Attenuation Index (FAI) during routine heart check-ups. This innovative approach enhances the diagnostic accuracy of coronary angiograms, allowing healthcare professionals to identify inflammation in the coronary arteries and predict risks of heart attacks, strokes, and diabetes. Through its proprietary technology, Caristo Diagnostics aims to support medical professionals in making informed treatment decisions to better manage cardiovascular health.
MIRICO Ltd. is a UK-based laser spectroscopy instrumentation company formed in 2015 as a spin-out from the Science and Technology Facilities Council. The technology underpinning MIRICO was developed by the RAL Space Laser Spectroscopy Team, led by Dr. Damien Weidmann. The laser spectroscopy team consists of 8 senior scientists who carry out cutting edge research and development. Over the years they have developed a range of spectroscopy techniques that overcome the major downfalls of current technologies. The company was formed to commercialise and take these technologies to market.
Developer of perovskite-based display materials intended to secure fundamental IP with a strong, scientific foundation. The company's technologies are based on the use of innovative new materials built around metal halide perovskites which can be synthesized from low-temperature alternative processes using earth-abundant precursor materials, enabling scientists to get bright and colorful light-emitting materials and technologies for TV and displays.
Closed Loop Medicine Ltd is a healthcare technology company based in Cambridge, United Kingdom, founded in 2017. The company focuses on developing innovative therapeutic solutions that combine established medications with proprietary digital therapeutics. By digitizing and capturing data throughout the entire care continuum, Closed Loop Medicine seeks to create dynamic, personalized treatment regimens tailored to individual patient needs. Their pipeline includes integrated approaches that address significant health challenges such as sleep disorders, hypertension, chronic pain, and diabetes. Through real-time feedback and advanced care pathways, Closed Loop Medicine aims to enhance patient outcomes and improve the overall efficiency of healthcare delivery.
Iothic specializes in developing IoT end-to-end systems that incorporate post-quantum resistant security features. The company offers a decentralized platform aimed at providing point-to-point quantum-resistant authentication. This platform is designed to deliver secure, scalable, and robust authentication and authorization techniques that can operate across various operating systems, protocols, communication layers, and IoT stacks. By enabling network providers to swiftly establish autonomous authentication services, Iothic supports a range of applications from simple sensors to complex IoT systems, thereby enhancing the overall security and interoperability of IoT networks.
Caristo Diagnostics Limited, based in Oxford, United Kingdom, specializes in artificial intelligence-driven software for cardiovascular diagnostics. Founded in 2018, the company focuses on improving heart health assessments through its advanced imaging technology. By developing tools that analyze Cardiac Computed Tomography Angiography (CCTA), Caristo enables the measurement of Fat Attenuation Index (FAI) during routine heart check-ups. This innovative approach enhances the diagnostic accuracy of coronary angiograms, allowing healthcare professionals to identify inflammation in the coronary arteries and predict risks of heart attacks, strokes, and diabetes. Through its proprietary technology, Caristo Diagnostics aims to support medical professionals in making informed treatment decisions to better manage cardiovascular health.
Kinomica Limited is a diagnostics and research company focused on medicine, particularly in cancer treatment. It has developed KScan, a biomarker and molecular diagnostics platform designed to measure intracellular kinase activity and cell-signalling pathways in cells and tissues. This platform utilizes advanced bioinformatics and phosphoproteomics analytical methods, allowing for direct activity measurements of various endogenous kinases and extensive coverage of cell signalling networks. By providing these insights, Kinomica aims to enhance personalized treatment decisions in anticancer therapies, enabling patients and healthcare providers to better understand disease mechanisms and improve drug targeting and biomarker identification. Founded in 2016 and based in Macclesfield, United Kingdom, the company was previously known as Pronostics Ltd. before rebranding in May 2017.
MicrofluidX Ltd is a company focused on advancing cell bioprocessing for autologous cell and gene therapy manufacturing. Founded in 2018 and headquartered in London, United Kingdom, the company has developed an innovative microfluidic bioprocessing system that integrates various cell culture functions, including seeding, expansion, differentiation, transduction, washing, sorting, concentration, sampling, and harvesting within a single, automated, closed system. This technology addresses challenges related to process control, scalability, and cost in cell bioprocessing, enabling biologists to efficiently conduct process development by exploring numerous cell culture conditions.
LettUs Grow, founded in 2015 and based in Bristol, United Kingdom, specializes in aeroponic irrigation and control technology designed for indoor farming. The company offers innovative aeroponic hardware that allows plants to grow without soil by using a fine mist for watering, complemented by LED lighting for photosynthesis. This technology aims to enhance the efficiency and sustainability of vertical farms while significantly reducing waste and carbon footprints. LettUs Grow has demonstrated notable yield improvements and is in the process of establishing Europe's first commercial-scale aeroponic vertical farm. The company is also expanding its capabilities and exploring global market opportunities, which are projected to grow at 27% annually. Its partnerships include various organizations such as the University of Bristol and Bethnal Green Ventures, reflecting a strong commitment to advancing sustainable food production in urban settings.
Wayland Additive is a company based in Huddersfield, United Kingdom, specializing in the development, manufacture, and distribution of metal additive manufacturing 3D printing machines. Founded in 2019, the company focuses on advancing electron beam 3D printing technology, aiming to serve industrial end-users in sectors such as aerospace and medical. Wayland Additive’s machines are designed to provide superior process monitoring, control, and versatility, enabling the use of high-performance materials that are challenging to work with. This innovation allows clients to achieve high precision and complexity in their manufacturing processes, thereby enhancing product performance across various industries, including energy and tooling.
Closed Loop Medicine Ltd is a healthcare technology company based in Cambridge, United Kingdom, founded in 2017. The company focuses on developing innovative therapeutic solutions that combine established medications with proprietary digital therapeutics. By digitizing and capturing data throughout the entire care continuum, Closed Loop Medicine seeks to create dynamic, personalized treatment regimens tailored to individual patient needs. Their pipeline includes integrated approaches that address significant health challenges such as sleep disorders, hypertension, chronic pain, and diabetes. Through real-time feedback and advanced care pathways, Closed Loop Medicine aims to enhance patient outcomes and improve the overall efficiency of healthcare delivery.
Verdel Instruments Ltd specializes in the development of two-dimensional mass spectrometry (2DMS) technology, focusing on equipment for structural analysis and sequencing. Established in 2018 and located in Coventry, United Kingdom, the company provides advanced mass spectrometry solutions utilized in analytical laboratories. These solutions enable the identification of key components and impurities across various sectors, including biopharmaceuticals, food, chemical products, and environmental analysis. By allowing researchers to obtain structural information from complex mixtures, Verdel Instruments plays a crucial role in enhancing the accuracy and efficiency of analytical processes.
Closed Loop Medicine Ltd is a healthcare technology company based in Cambridge, United Kingdom, founded in 2017. The company focuses on developing innovative therapeutic solutions that combine established medications with proprietary digital therapeutics. By digitizing and capturing data throughout the entire care continuum, Closed Loop Medicine seeks to create dynamic, personalized treatment regimens tailored to individual patient needs. Their pipeline includes integrated approaches that address significant health challenges such as sleep disorders, hypertension, chronic pain, and diabetes. Through real-time feedback and advanced care pathways, Closed Loop Medicine aims to enhance patient outcomes and improve the overall efficiency of healthcare delivery.
Caristo Diagnostics Limited, based in Oxford, United Kingdom, specializes in artificial intelligence-driven software for cardiovascular diagnostics. Founded in 2018, the company focuses on improving heart health assessments through its advanced imaging technology. By developing tools that analyze Cardiac Computed Tomography Angiography (CCTA), Caristo enables the measurement of Fat Attenuation Index (FAI) during routine heart check-ups. This innovative approach enhances the diagnostic accuracy of coronary angiograms, allowing healthcare professionals to identify inflammation in the coronary arteries and predict risks of heart attacks, strokes, and diabetes. Through its proprietary technology, Caristo Diagnostics aims to support medical professionals in making informed treatment decisions to better manage cardiovascular health.
Oxford Space Systems Limited is a space technology company based in Harwell, United Kingdom, founded in 2013. The firm specializes in developing, manufacturing, and marketing deployable hardware structures for space applications, including deployable antennas, composite linear boom systems, and hinge systems. By employing innovative design techniques, such as origami, and utilizing novel proprietary materials, Oxford Space Systems creates products that are lighter, less complex, and more cost-effective than traditional alternatives. The company has achieved significant milestones, including a record for the fastest development of a new product, the AstroTube Boom, which was successfully deployed in orbit within 30 months. With a team of 18 professionals possessing over 100 years of combined experience in the space sector, Oxford Space Systems has engaged in various collaborations, including government-supported projects with leading European satellite manufacturers and commercial contracts in Asia and the U.S. In 2018, the company relocated to a custom facility within the Harwell Space Cluster, enhancing its capabilities to meet security standards for defense and security contracts.
MIRICO Ltd. is a UK-based laser spectroscopy instrumentation company formed in 2015 as a spin-out from the Science and Technology Facilities Council. The technology underpinning MIRICO was developed by the RAL Space Laser Spectroscopy Team, led by Dr. Damien Weidmann. The laser spectroscopy team consists of 8 senior scientists who carry out cutting edge research and development. Over the years they have developed a range of spectroscopy techniques that overcome the major downfalls of current technologies. The company was formed to commercialise and take these technologies to market.
Closed Loop Medicine Ltd is a healthcare technology company based in Cambridge, United Kingdom, founded in 2017. The company focuses on developing innovative therapeutic solutions that combine established medications with proprietary digital therapeutics. By digitizing and capturing data throughout the entire care continuum, Closed Loop Medicine seeks to create dynamic, personalized treatment regimens tailored to individual patient needs. Their pipeline includes integrated approaches that address significant health challenges such as sleep disorders, hypertension, chronic pain, and diabetes. Through real-time feedback and advanced care pathways, Closed Loop Medicine aims to enhance patient outcomes and improve the overall efficiency of healthcare delivery.
Base4 Innovation Ltd. is a company based in Cambridge, United Kingdom, that specializes in the development of advanced detection platforms for the healthcare and life sciences sectors. Founded in 2007, Base4 focuses on cutting-edge technologies for single-molecule analysis, particularly through its microdroplet-based sequencing technology. This innovative approach allows for pathogen screening and DNA analysis by generating long reads from individual DNA molecules without the need for initial amplification. The technology aims to enhance the understanding and prediction of diseases while providing more accurate and cost-effective sequencing data for large populations. In addition to its technical advancements, Base4 is committed to building a valuable portfolio of intellectual property and expertise.
Arquer Diagnostics Ltd. specializes in the design, development, and commercialization of non-invasive immunoassay diagnostic tests for bladder and prostate cancer. The company offers an enzyme-linked immunosorbent assay (ELISA) for measuring small amounts of substances in body fluids, including a CE-marked ELISA kit for Mcm5, which is utilized in hospital pathology laboratories. Additionally, Arquer provides a point-of-care system that features a robust reader instrument and disposable cartridges, allowing for immediate testing in urology clinics, hospital laboratories, and general practitioners' surgeries. Founded in 2005 and formerly known as UroSens Ltd., the company is headquartered in Sunderland, United Kingdom, and is committed to improving cancer detection and monitoring to enhance patient outcomes.
OxSonics Limited develops and commercializes SonoTran, an oncological drug delivery platform and injectable sono-sensitive particles. Its SonoTran drug delivery platform delivers drugs throughout tumours, including to the areas that lie furthest from blood vessels. The company also develops a pipeline of therapies for the treatment of solid tumours, mCRC, and pancreatic ductal adenocarcinoma. OxSonics Limited was founded in 2013 and is based in Oxford, United Kingdom.
Keit Ltd. is a company based in Didcot, United Kingdom, specializing in the design and manufacture of advanced spectrometers and related instruments, particularly in the field of Fourier Transform Infrared (FTIR) spectroscopy. Founded in 2012, Keit has developed the microFTS®, a compact and robust FTIR spectrometer that excels in extreme environments, making it particularly suitable for applications in the Pharmaceutical, Chemical, Oil & Gas, and Food & Beverage industries. The microFTS® enables real-time analysis of liquid states, facilitating process monitoring and control in various manufacturing settings. Its innovative design allows for direct mounting on manufacturing vessels or connection to process lines, empowering chemical engineering and production teams to make timely and informed decisions that enhance process efficiency and optimization.
MIRICO Ltd. is a UK-based laser spectroscopy instrumentation company formed in 2015 as a spin-out from the Science and Technology Facilities Council. The technology underpinning MIRICO was developed by the RAL Space Laser Spectroscopy Team, led by Dr. Damien Weidmann. The laser spectroscopy team consists of 8 senior scientists who carry out cutting edge research and development. Over the years they have developed a range of spectroscopy techniques that overcome the major downfalls of current technologies. The company was formed to commercialise and take these technologies to market.
User Replay Limited develops digital customer experience analytics software solutions that help businesses enhance their online interactions with customers. Founded in 2009 and based in Reading, United Kingdom, the company provides an integrated customer experience platform that utilizes machine learning to identify and analyze user sessions effectively. Its Active CX platform records and analyzes digital customer interactions, enabling businesses to uncover and address conversion barriers such as usability issues, confusing business logic, and technical problems. User Replay’s software is designed to improve user experience and increase conversion rates, which can have a direct impact on sales. The company serves various sectors, including financial services, insurance, retail, and travel, with operations across Europe, the Middle East, Africa, and the United States. User Replay's solutions are utilized by over 20 leading brands, including notable retailers in the US and Europe.
Oxford Cancer Biomarkers is developing and commercializing a suite of colorectal cancer biomarker tests to improve the current treatment pathway. Oxford Cancer Biomarkers is closely affiliated with Institute of Cancer Medicine at Oxford University, where its founders lead translational cancer science research groups. Oxford Cancer Biomarkers has also partnered with pharmaceutical companies to use its discovery platforms CancerNav® and ToxNavTM to develop companion diagnostic tests for pipeline drugs.
Azellon Limited is a company based in London, United Kingdom, that specializes in the development and commercialization of a unique tissue repair technology utilizing mesenchymal stem cells combined with a biological scaffold. The company's primary product, Cell Bandage, is designed for the repair of avascular meniscal tears in the knee, addressing a significant issue in orthopedic treatment where surgeons often resort to partial or complete meniscus removal. This conventional approach can lead to osteoarthritic changes in the knee joint over time. Developed by Professor Anthony Hollander, Azellon's technology has demonstrated notable success in in-vitro models over a five-year research period. Established in 2007, Azellon Limited aims to offer a more effective solution for knee injuries that preserves the meniscus and promotes natural healing.
Arquer Diagnostics Ltd. specializes in the design, development, and commercialization of non-invasive immunoassay diagnostic tests for bladder and prostate cancer. The company offers an enzyme-linked immunosorbent assay (ELISA) for measuring small amounts of substances in body fluids, including a CE-marked ELISA kit for Mcm5, which is utilized in hospital pathology laboratories. Additionally, Arquer provides a point-of-care system that features a robust reader instrument and disposable cartridges, allowing for immediate testing in urology clinics, hospital laboratories, and general practitioners' surgeries. Founded in 2005 and formerly known as UroSens Ltd., the company is headquartered in Sunderland, United Kingdom, and is committed to improving cancer detection and monitoring to enhance patient outcomes.
Sensiia Limited is a company based in Cambridge, United Kingdom, that specializes in the manufacturing of sensor-based fertility wearable devices, notably the DuoFertility system. Founded in 2006 and formerly known as Cambridge Temperature Concepts Limited, Sensiia develops a comprehensive fertility solution that includes a wearable device and a supporting mobile application. DuoFertility tracks and predicts female ovulation cycles, providing users with insights into their most fertile windows up to 10 days in advance. This system is unique in offering personalized support from fertility experts, enhancing the user experience in their journey toward pregnancy. Clinically proven to be as effective as the first cycle of IVF, DuoFertility has demonstrated significant success rates in helping couples conceive, with results comparable to traditional fertility treatments. Sensiia's innovative approach addresses a critical need in reproductive health, aiming to improve outcomes for individuals seeking to expand their families.
Momentum Bioscience Ltd is a company based in Cardiff, United Kingdom, specializing in the development of rapid diagnostic tests for critical clinical specimens. Founded in 2005, the company focuses on Enzyme Mediated Amplification (EMA) technology, which allows for the ultrasensitive and universal detection of viable bacteria and fungi in blood and other normally sterile body fluids. This innovative approach significantly reduces detection time to less than two hours, compared to the traditional 1-5 days required by laboratory techniques. Momentum Bioscience serves essential sectors such as neonatal care, emergency care, and critical care, providing vital tools for microbiology laboratories to identify infections quickly and accurately.
Oxford Space Systems Limited is a space technology company based in Harwell, United Kingdom, founded in 2013. The firm specializes in developing, manufacturing, and marketing deployable hardware structures for space applications, including deployable antennas, composite linear boom systems, and hinge systems. By employing innovative design techniques, such as origami, and utilizing novel proprietary materials, Oxford Space Systems creates products that are lighter, less complex, and more cost-effective than traditional alternatives. The company has achieved significant milestones, including a record for the fastest development of a new product, the AstroTube Boom, which was successfully deployed in orbit within 30 months. With a team of 18 professionals possessing over 100 years of combined experience in the space sector, Oxford Space Systems has engaged in various collaborations, including government-supported projects with leading European satellite manufacturers and commercial contracts in Asia and the U.S. In 2018, the company relocated to a custom facility within the Harwell Space Cluster, enhancing its capabilities to meet security standards for defense and security contracts.
Oxford Photovoltaics Limited develops and commercializes thin-film perovskite solar cells that are printed directly onto silicon solar cells, CIGS solar cells, or glass. Oxford Photovoltaics Limited has a strategic partnership with Meyer Burger Technology Ltd. The company was incorporated in 2010 and is based in Oxford, United Kingdom.
OrganOx Limited, founded in 2008 and based in Oxford, United Kingdom, specializes in organ preservation and transplantation technology, particularly for liver transplants. The company has developed the Metra device, which employs normothermic preservation technology to store livers outside the body at normal body temperature. This innovative approach mimics the conditions of the human body by continuously perfusing the liver with oxygen-carrying red cells and nutrients, thereby preventing the decay of the organ before transplantation. The Metra device enables the liver to produce bile, metabolize glucose, and maintain a physiological pH level, ultimately enhancing the viability of the organ for transplant. OrganOx's research and development efforts are rooted in the work of Prof Peter Friend and Prof Constantin Coussios at the University of Oxford.
Crysalin Limited, founded in June 2007 and based in London, specializes in the research and development of crysalin lattice technology, which is derived from patented work initiated in 2002 at the Oxford University Laboratory of Molecular Biophysics. The company's core product, crysalins, is a protein-based nanotechnology that significantly enhances the determination of protein structures, particularly for challenging targets such as membrane proteins and soluble proteins with flexible regions. Crysalins enable the resolution of three-dimensional molecular structures using X-ray and electron microscopy techniques, where traditional methods have struggled. In addition to protein structure determination, crysalins hold potential applications in biosensor development and optoelectronics, showcasing the versatility and innovative capacity of the technology.
Diamond Microwave Devices Ltd. engages in the development of semiconductor devices based on CVD diamond. Its devices are used in civil and defense systems for microwave power amplifier and transmitter applications. The company was founded in 2006 and is based in Leeds, the United Kingdom. Diamond Microwave Devices Ltd. operates as a subsidiary of Element Six (Pty) Ltd.