SiTration
Seed Round in 2024
SiTration, founded in Cambridge, Massachusetts in 2020 by Brendan Smith, specializes in developing ultra-durable filtration membrane technology. This technology is designed to efficiently separate substances in harsh and challenging industrial environments while reducing energy consumption compared to conventional methods. The company's membranes combine the advantages of various state-of-the-art commercial membranes, offering users resource-efficient operations even in unpleasant industrial settings.
Overjet develops AI-based software for dental clinical data analysis. Founded by experts from MIT and Harvard University, it offers solutions like clinical optimization software for practice performance assessment and utilization software for claims review to ensure appropriate care at lower costs. Its FDA-cleared technology enables precise detection of oral anomalies in X-rays.
Elemind
Seed Round in 2024
Elemind Technologies is a neurotechnology company based in Cambridge, Massachusetts, founded in 2017. The company specializes in developing wearable devices that utilize innovative neuromodulation techniques to process and compute brainwave activity. By precisely timing audio output, Elemind's technology aims to shape brainwaves and alter brain states, enabling users to enhance attention and improve sleep. Through its cutting-edge approach, Elemind seeks to advance the understanding and manipulation of brain functions for better cognitive health and performance.
Founded in 2021, Ketryx is headquartered in Cambridge, Massachusetts. It empowers regulated software teams to deliver safer software faster by providing an AI-driven compliance platform that integrates with popular tools like Jira and GitHub. This platform generates FDA-ready documentation, maintains traceability across systems, and enforces quality procedures.
Bitpart AI
Seed Round in 2023
Bitpart AI is a Boston-based startup that specializes in providing pre-trained non-player characters (NPCs) for game developers at all levels. The company utilizes generative AI and automated planners to create NPCs with intelligence, specific behaviors, and customizable dialogue. These characters can interact with the game environment and engage in dynamic conversations with one another. Bitpart AI's offerings are designed to be easily integrated into any game engine or user-generated content platform, thereby enhancing the immersive experience for players. Additionally, the company is developing the Character Hub, a platform where creators can browse, customize, and share NPCs, allowing them to refine dialogue, moods, and personality traits to fit various use cases.
SiTration
Pre Seed Round in 2022
SiTration, founded in Cambridge, Massachusetts in 2020 by Brendan Smith, specializes in developing ultra-durable filtration membrane technology. This technology is designed to efficiently separate substances in harsh and challenging industrial environments while reducing energy consumption compared to conventional methods. The company's membranes combine the advantages of various state-of-the-art commercial membranes, offering users resource-efficient operations even in unpleasant industrial settings.
Volta Labs
Series A in 2022
Volta Labs, Inc. is a biotechnology company based in Cambridge, Massachusetts, founded in 2018. The company specializes in engineering and developing innovative tools for biological automation, focusing on scalable automation solutions for genetic engineering. Its platform is designed to revolutionize genomics research by providing affordable genomic sample preparation and automation for complex biological workflows. By integrating expertise from engineering, surface chemistry, and molecular biology, Volta Labs aims to streamline sample processing and enhance the capabilities of biotech organizations in the next generation of genomic automation.
OPT Industries
Series A in 2022
Founded in Cambridge, Massachusetts in 2019 by Jifei Ou, OPT Industries specializes in precision-engineered products at the micron-scale. Utilizing vertically integrated machinery, software, and design expertise, they provide customers with high-volume production and shortened lead times.
Overjet develops AI-based software for dental clinical data analysis. Founded by experts from MIT and Harvard University, it offers solutions like clinical optimization software for practice performance assessment and utilization software for claims review to ensure appropriate care at lower costs. Its FDA-cleared technology enables precise detection of oral anomalies in X-rays.
Overjet develops AI-based software for dental clinical data analysis. Founded by experts from MIT and Harvard University, it offers solutions like clinical optimization software for practice performance assessment and utilization software for claims review to ensure appropriate care at lower costs. Its FDA-cleared technology enables precise detection of oral anomalies in X-rays.
FIGUR8, Inc. is a Boston-based company founded in 2016 as an MIT spin-off, specializing in advanced wearable sensor technology to measure body movement related to musculoskeletal (MSK) conditions. The company's innovative solution integrates smart biosensors, intuitive software, and artificial intelligence to collect and analyze movement data without the need for cumbersome cameras. This technology accurately identifies the sources of MSK pathology, providing essential insights that enhance patient recovery and care management. By enabling trainers, therapists, and physicians to objectively assess musculoskeletal performance, FIGUR8's platform not only improves access to care but also empowers patients to take control of their health. The comprehensive approach records value throughout the entire episode of care, from injury to recovery, ultimately reducing costs and improving health outcomes.
Array Insights
Seed Round in 2020
Array Insights is an IT firm focused on developing artificial intelligence-driven solutions aimed at managing patient and caregiver narratives. The company offers a clinical data registry platform that enables the secure sharing of sensitive healthcare data while maintaining ownership and compliance. By employing advanced encryption techniques, Array Insights connects data algorithms to facilitate the analysis and training of AI models without compromising security or privacy. This platform allows hospitals and healthcare providers to effectively control, track, and trace patient information, thereby enhancing research capabilities and accelerating the pace of innovation in the healthcare sector. Founded in 2017 and based in Cambridge, Massachusetts, Array Insights is dedicated to improving data accessibility while safeguarding proprietary and sensitive information.
Labby Inc. is a technology company based in Cambridge, Massachusetts, specializing in smartphone-based optical spectrometry for agricultural applications. Founded in 2017, Labby develops an artificial intelligence-driven platform that translates raw optical data into actionable insights, primarily for farmers and dairy processors. Its flagship product allows for rapid and precise testing of milk composition, facilitating early mastitis detection and enabling timely intervention. Additionally, Labby's technology is applicable across various sectors, including the detection of spoilage, adulterants, and contamination in the supply chain, as well as providing analytics for tracking harvest cycles and meteorological data mapping. The company also caters to the beer and wine industries, offering portable testing devices for quality control and counterfeit detection, serving a diverse clientele that ranges from large breweries to homebrewers.
Augmental
Seed Round in 2020
Augmental Technologies, Inc., established in 2019 and headquartered in Boston, Massachusetts, specializes in developing innovative, hands-free technology that integrates with the human body. The company focuses on augmented reality and assistive technology, aiming to provide information access and assistance to users with both situational and severe motor impairments. By targeting the mouth as an unexplored interface for human-computer interaction, Augmental enables users to overcome physical and sensory limitations, enhancing autonomy and mobility, particularly for those living with upper extremity paralysis.
Wise Systems
Series B in 2020
Wise Systems develops autonomous dispatch and routing software for last-mile delivery, using machine learning to automatically schedule, monitor, and adjust routes in real time to improve fleet efficiency and customer service. The platform analyzes orders, optimizes routes, tracks progress and ETAs, and evaluates driver performance, while providing a customer portal with real-time order visibility. It also includes Smart Reservation Management that lets customers select delivery dates and times. Serving industries such as food and beverage, parcel and courier, retail, field service, and other logistics sectors, Wise Systems processes millions of data points to deliver thousands of decisions daily. The company originated from MIT research and operates from Massachusetts, delivering scalable solutions that reduce mileage, boost fleet utilization, and minimize late deliveries.
Overjet
Seed Round in 2020
Overjet develops AI-based software for dental clinical data analysis. Founded by experts from MIT and Harvard University, it offers solutions like clinical optimization software for practice performance assessment and utilization software for claims review to ensure appropriate care at lower costs. Its FDA-cleared technology enables precise detection of oral anomalies in X-rays.
MitoLab
Venture Round in 2020
MitoLab is a biotechnology company building a scalable platform for mitochondrial genome engineering. It creates and sells products for use in non-clinical scientific research scenarios. The company’s products are designed to be used in non-clinical research projects assessing the utility of chemical compounds for mitochondrial medicine. Their customers range from multinational companies to individuals specializing in mitochondrial, metabolic, and anti-aging research.
Founded by Fahim Farzadfard and Louis J. Kang in 2020 and is headquartered in Allston, Massachusetts, USA.
DeepCure
Seed Round in 2020
DeepCure Inc. is a biotechnology company based in Boston, Massachusetts, specializing in artificial intelligence-driven drug discovery. Founded in 2018, DeepCure develops innovative solutions for small-molecule drug development, utilizing advanced deep learning algorithms and a proprietary database of chemical compounds. The company offers services such as De-novo Lead Discovery, which employs AI algorithms to assess potential drug candidates from a virtual library, and Artificial Intelligence-driven Lead Optimization, aimed at enhancing drug development processes. Additionally, DeepCure's platform includes a molecular database designed to maximize the diversity and synthesizability of chemical compounds. By integrating AI predictive modeling and a feedback loop, DeepCure focuses on creating effective therapeutics for unmet medical needs, ultimately aiming to expedite the development of novel precision medicines.
Rune AI Inc. offers a mobile application designed to enhance the gaming experience for mobile gamers by connecting them through voice chat and facilitating the formation of teams. The platform, known as Rune, utilizes artificial intelligence to match players based on similar trophies and shared languages, enabling users to find compatible teammates effortlessly. In addition to matchmaking, Rune allows players to track their gaming statistics and earn rewards such as brawl boxes. Incorporated in 2018 and headquartered in Cambridge, Massachusetts, Rune AI Inc. aims to redefine how mobile gamers connect and collaborate, creating a more engaging community for shared gaming experiences.
FIGUR8, Inc. is a Boston-based company founded in 2016 as an MIT spin-off, specializing in advanced wearable sensor technology to measure body movement related to musculoskeletal (MSK) conditions. The company's innovative solution integrates smart biosensors, intuitive software, and artificial intelligence to collect and analyze movement data without the need for cumbersome cameras. This technology accurately identifies the sources of MSK pathology, providing essential insights that enhance patient recovery and care management. By enabling trainers, therapists, and physicians to objectively assess musculoskeletal performance, FIGUR8's platform not only improves access to care but also empowers patients to take control of their health. The comprehensive approach records value throughout the entire episode of care, from injury to recovery, ultimately reducing costs and improving health outcomes.
Fathom
Non Equity Assistance in 2019
Fathom is a company that specializes in creating hologram-like 3D experiences through the use of standard printers, inks, and media. Founded in 2014 and based in Boston, Massachusetts, Fathom enables users to print special patterns duplex on clear film, resulting in 3D objects that appear to extend significantly beyond the film's thickness. The firm's innovative approach allows for the production of immersive visual experiences that are accessible and can be created using readily available printing technology.
Affectiva
Series B in 2019
Affectiva, Inc. is a Boston-based company that specializes in emotion-sensing artificial intelligence software. Founded in 2009 as a spin-off from the MIT Media Lab, Affectiva has established itself as a pioneer in the Emotion AI sector. The company develops advanced technology that utilizes deep learning, computer vision, and speech science to analyze subtle facial and vocal expressions, enabling the detection of nuanced human emotions and cognitive states. Its offerings include a software development kit, a cloud-based API, and in-lab biometric solutions that assist brands, advertisers, and market researchers in understanding consumer engagement with digital content. Affectiva's technology is widely adopted across various industries, including advertising, automotive, social robotics, and healthcare. It serves a broad clientele, including 25 percent of the Fortune Global 500 companies, helping them enhance user interactions and improve the effectiveness of their advertising and communication strategies.
OPT Industries
Seed Round in 2019
Founded in Cambridge, Massachusetts in 2019 by Jifei Ou, OPT Industries specializes in precision-engineered products at the micron-scale. Utilizing vertically integrated machinery, software, and design expertise, they provide customers with high-volume production and shortened lead times.
Wise Systems
Series A in 2018
Wise Systems develops autonomous dispatch and routing software for last-mile delivery, using machine learning to automatically schedule, monitor, and adjust routes in real time to improve fleet efficiency and customer service. The platform analyzes orders, optimizes routes, tracks progress and ETAs, and evaluates driver performance, while providing a customer portal with real-time order visibility. It also includes Smart Reservation Management that lets customers select delivery dates and times. Serving industries such as food and beverage, parcel and courier, retail, field service, and other logistics sectors, Wise Systems processes millions of data points to deliver thousands of decisions daily. The company originated from MIT research and operates from Massachusetts, delivering scalable solutions that reduce mileage, boost fleet utilization, and minimize late deliveries.
Tulip Interfaces
Seed Round in 2016
Tulip Interfaces is a technology company that creates shop‑floor applications for the manufacturing sector. Its no‑code platform integrates sensor data, digital work instructions, real‑time visualization, and operator inputs to connect existing equipment and streamline operations. The solution is used by firms in consumer electronics, pharmaceuticals, apparel, medical devices, aerospace, defense, automotive, and contract manufacturing to improve productivity, quality, and operational visibility. Founded in 2012, the company is headquartered in Somerville, Massachusetts.
Waylens
Seed Round in 2015
Waylens, Inc. is a Boston-based company that specializes in designing and developing advanced camera systems tailored for vehicles. Founded in 2014, Waylens creates technology that captures driving experiences by integrating data from multiple sensors, including the vehicle's OBD computer through Bluetooth connectivity. This innovative approach allows users to produce hyper-realistic videos of their journeys, which can be easily saved and shared. Additionally, Waylens offers solutions for fleet management, delivering critical insights and real-time data to track both driver and vehicle performance. This functionality supports clients in optimizing costs while enhancing their fleet performance metrics and maintaining a comprehensive video library.
Formlabs
Seed Round in 2011
Formlabs designs and manufactures professional 3D printing systems and materials for engineers, designers, educators, and manufacturers. The company offers high-resolution stereolithography printers such as Form 3, Form 3B, and Form 3L, along with post-processing equipment Form Wash and Form Cure, and the SLS-based Fuse 1 printer. It develops in-house high-performance resins and materials used across industries including education, dentistry, healthcare, jewelry, and manufacturing. Its software ecosystem includes PreForm, which prepares models for printing, and Form Cell for automated manufacturing. Formlabs serves customers worldwide and maintains headquarters in Somerville, Massachusetts with international offices. The company focuses on enabling designers and engineers to produce detailed, functional parts and complex geometries, expanding access to professional-grade 3D printing through scalable hardware, materials, and software solutions.