Excel Venture Management

InfoBionic, Inc., incorporated in 2011 and based in Lowell, Massachusetts, specializes in remote patient monitoring technologies, particularly focusing on cardiac arrhythmia detection. The company has developed the MoMe System, a cloud-based platform that allows for continuous monitoring of electrocardiogram, respiration, and motion data. This wireless system streamlines the remote patient monitoring process, enhancing both clinical efficiency and patient care by enabling healthcare providers to access patient data anytime and anywhere. InfoBionic's innovative approach aims to transform the economics of cardiac diagnostic services, benefiting both physicians and patients through improved detection and treatment of cardiac complications.

Ayogo Health Inc., established in 2008 and headquartered in Vancouver, Canada, specializes in developing digital health solutions that engage patients and improve adherence to treatment plans for chronic conditions. The company's core products include GoodLife, a customizable platform combining gamification, incentives, and social features, and Alternate Reality Games, which blend online and real-world elements for educational purposes. Ayogo serves clients such as insurers, healthcare providers, and pharmaceutical companies by applying behavioral psychology and social gaming principles to enhance patient outcomes. The company's collaborative approach involves meaningful engagement with patients, end-users, and clients throughout project development.

Neosensory, Inc. is a company that specializes in developing wearable devices aimed at enhancing sensory perception for individuals. Founded in 2015 and based in San Mateo, California, Neosensory offers products such as Buzz, which utilizes vision-to-touch sensory substitution technology to assist blind individuals. The company focuses on transmitting various data streams to the brain through the sense of touch, leveraging the skin's potential for information delivery. Their innovative approach includes building hearing assistive technology that allows users to perceive sound through vibrations on the skin. Neosensory also provides a companion application for its products, enhancing the user experience and accessibility of information.

ClearDATA Networks, Inc. specializes in providing cloud computing and information security solutions tailored for the healthcare sector, serving healthcare providers, life sciences organizations, and payers. Established in 2009 and headquartered in Austin, Texas, the company offers a comprehensive multi-cloud platform that automates, protects, and manages healthcare applications and data. Its key products include ClearDATA Comply, a software solution for maintaining healthcare cloud compliance, and ClearDATA Assess, which aids in conducting mandatory HIPAA Security Risk Assessments. Additionally, ClearDATA Locate Mask allows organizations to utilize unstructured datasets while safeguarding sensitive information. The company is recognized for its HITRUST-certified cloud services, which ensure robust data privacy protections and extensive compliance capabilities, helping healthcare organizations leverage data effectively while enhancing operational efficiency.

Openwater is a medical technology startup founded in 2016 and based in San Francisco, California. The company specializes in developing advanced wearable devices that utilize novel optoelectronics to achieve MRI-like resolution for medical diagnostics and treatments. By employing LCDs with small pixels, Openwater's technology creates holographic images that reduce scattering, enabling physicians to visualize the inner workings of the body and brain at a cellular level. This innovation allows for precise diagnosis and targeted treatment of diseases by manipulating or destroying individual cells without damaging surrounding tissue. Openwater aims to revolutionize medical imaging and improve patient outcomes through its cutting-edge approach.

InfoBionic, Inc., incorporated in 2011 and based in Lowell, Massachusetts, specializes in remote patient monitoring technologies, particularly focusing on cardiac arrhythmia detection. The company has developed the MoMe System, a cloud-based platform that allows for continuous monitoring of electrocardiogram, respiration, and motion data. This wireless system streamlines the remote patient monitoring process, enhancing both clinical efficiency and patient care by enabling healthcare providers to access patient data anytime and anywhere. InfoBionic's innovative approach aims to transform the economics of cardiac diagnostic services, benefiting both physicians and patients through improved detection and treatment of cardiac complications.

Openwater is a medical technology startup founded in 2016 and based in San Francisco, California. The company specializes in developing advanced wearable devices that utilize novel optoelectronics to achieve MRI-like resolution for medical diagnostics and treatments. By employing LCDs with small pixels, Openwater's technology creates holographic images that reduce scattering, enabling physicians to visualize the inner workings of the body and brain at a cellular level. This innovation allows for precise diagnosis and targeted treatment of diseases by manipulating or destroying individual cells without damaging surrounding tissue. Openwater aims to revolutionize medical imaging and improve patient outcomes through its cutting-edge approach.

ClearDATA Networks, Inc. specializes in providing cloud computing and information security solutions tailored for the healthcare sector, serving healthcare providers, life sciences organizations, and payers. Established in 2009 and headquartered in Austin, Texas, the company offers a comprehensive multi-cloud platform that automates, protects, and manages healthcare applications and data. Its key products include ClearDATA Comply, a software solution for maintaining healthcare cloud compliance, and ClearDATA Assess, which aids in conducting mandatory HIPAA Security Risk Assessments. Additionally, ClearDATA Locate Mask allows organizations to utilize unstructured datasets while safeguarding sensitive information. The company is recognized for its HITRUST-certified cloud services, which ensure robust data privacy protections and extensive compliance capabilities, helping healthcare organizations leverage data effectively while enhancing operational efficiency.

Oculus Health, Inc. operates a chronic care management platform designed to enhance the connection between healthcare providers and patients. Founded in 2014 and based in Irving, Texas, the company offers a comprehensive suite of services that includes shared care plans, access to medical assistants via online and phone support, and real-time monitoring of enrolled patients. Oculus Health integrates data from various healthcare sources, such as hospitals and laboratories, to facilitate seamless information exchange among care teams. The platform also features user-friendly web and mobile applications, remote monitoring capabilities, and patient engagement solutions. By providing transparent care plans, personalized health coaching, and a reminder system, Oculus Health aims to empower individuals in managing their health proactively and improving overall patient outcomes while supporting providers in navigating the evolving healthcare landscape.

Qstream, Inc. is a software company that specializes in developing a mobile sales acceleration platform designed to enhance job proficiency and influence behavior within sales teams. Founded in 2008 and headquartered in Burlington, Massachusetts, Qstream serves clients across various sectors, including technology, financial services, and life sciences. The company operates engineering facilities in Dublin, Ireland, and Hood River, Oregon, while maintaining sales headquarters in Maidenhead, United Kingdom, and an office in San Francisco. Qstream's micro-learning platform enables organizations to manage and measure the human aspects of sales performance, providing analytics-driven insights that facilitate team excellence.

Foodsmart is a digital nutrition platform focused on enhancing health outcomes through personalized dietary recommendations. The company aims to support individuals dealing with chronic diseases and food insecurity by collaborating with health plans and healthcare providers. Its online telehealth application offers real-time guidance across various settings, including homes, workplaces, grocery stores, and restaurants. This comprehensive approach enables users to make healthier food choices and select recipes that can mitigate chronic health issues, thereby promoting overall well-being. By providing access to affordable and tailored healthy eating options, Foodsmart strives to empower individuals to improve their nutrition and health.

InfoBionic, Inc., incorporated in 2011 and based in Lowell, Massachusetts, specializes in remote patient monitoring technologies, particularly focusing on cardiac arrhythmia detection. The company has developed the MoMe System, a cloud-based platform that allows for continuous monitoring of electrocardiogram, respiration, and motion data. This wireless system streamlines the remote patient monitoring process, enhancing both clinical efficiency and patient care by enabling healthcare providers to access patient data anytime and anywhere. InfoBionic's innovative approach aims to transform the economics of cardiac diagnostic services, benefiting both physicians and patients through improved detection and treatment of cardiac complications.

N-of-One, Inc. is a molecular decision support company specializing in the interpretation of molecular test results for cancer care. The company provides clinicians with insights into disease-specific biological relevance, clinical evidence, and associated therapies. It interprets next-generation sequencing (NGS) data from solid and hematological tumors, circulating tumor cells, and DNA, as well as conducting copy number analysis and immunohistochemistry. N-of-One offers services such as PrecisionInsights, which delivers comprehensive clinical interpretation reports for gene NGS panels, and TRIALMATCH, a solution for matching patients with clinical trials based on their specific profiles. The company collaborates with commercial and hospital laboratories, as well as precision medicine programs, to enhance cancer treatment strategies. Founded in 2007 and based in Lexington, Massachusetts, N-of-One, Inc. operates as a subsidiary of QIAGEN N.V.

WellDoc, Inc. is a healthcare technology company focused on chronic disease management, particularly diabetes. Founded in 2005 and headquartered in Baltimore, Maryland, with additional offices in Wilmington, Delaware, and Bengaluru, India, WellDoc develops innovative solutions that integrate into existing healthcare workflows. Its flagship platform, DiabetesManager, provides personalized, real-time coaching and support for patients and healthcare providers, facilitating self-management and adherence to treatment regimens. The platform features tools for medication reminders, alerts for out-of-range metrics, and cloud-based analytics for tracking health outcomes. Additionally, WellDoc offers BlueStar, a mobile prescription therapy solution that guides patients in managing their diabetes. The company serves various stakeholders in the healthcare ecosystem, including payors, employers, pharmaceutical companies, and medical device firms, and has established strategic partnerships to enhance its offerings.

ClearDATA Networks, Inc. specializes in providing cloud computing and information security solutions tailored for the healthcare sector, serving healthcare providers, life sciences organizations, and payers. Established in 2009 and headquartered in Austin, Texas, the company offers a comprehensive multi-cloud platform that automates, protects, and manages healthcare applications and data. Its key products include ClearDATA Comply, a software solution for maintaining healthcare cloud compliance, and ClearDATA Assess, which aids in conducting mandatory HIPAA Security Risk Assessments. Additionally, ClearDATA Locate Mask allows organizations to utilize unstructured datasets while safeguarding sensitive information. The company is recognized for its HITRUST-certified cloud services, which ensure robust data privacy protections and extensive compliance capabilities, helping healthcare organizations leverage data effectively while enhancing operational efficiency.

Ayogo Health Inc., established in 2008 and headquartered in Vancouver, Canada, specializes in developing digital health solutions that engage patients and improve adherence to treatment plans for chronic conditions. The company's core products include GoodLife, a customizable platform combining gamification, incentives, and social features, and Alternate Reality Games, which blend online and real-world elements for educational purposes. Ayogo serves clients such as insurers, healthcare providers, and pharmaceutical companies by applying behavioral psychology and social gaming principles to enhance patient outcomes. The company's collaborative approach involves meaningful engagement with patients, end-users, and clients throughout project development.

Orionis Biosciences is an early-stage biotechnology company dedicated to drug discovery and development, primarily targeting oncology and immunotherapies for diseases with significant unmet medical needs. Based in Waltham, Massachusetts, with additional research facilities in Ghent, Belgium, the company utilizes innovative technologies to create conditionally active drug modalities. Orionis employs mechanisms of molecular proximity and cooperativity to enhance drug potency and precision, leading to a diverse pipeline of drug candidates. These efforts include the development of small molecules that engage both adaptive and innate immune systems, paving the way for effective single-agent therapies for cancer and other life-threatening conditions. The company is supported by a team of experienced professionals and maintains strategic collaborations with leading research institutions, such as VIB in Belgium.

Gemphire Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for dyslipidemia and nonalcoholic fatty liver disease (NAFLD/NASH). The company is known for its development of gemcabene, a novel oral medication aimed at lowering LDL cholesterol levels in patients who have not achieved their lipid-lowering goals, particularly those on maximally tolerated statin therapy. Gemphire has conducted multiple Phase IIb clinical trials for gemcabene, targeting conditions such as homozygous familial hypercholesterolemia, heterozygous familial hypercholesterolemia, atherosclerotic cardiovascular disease, and severe hypertriglyceridemia. Founded in 2008 and headquartered in Livonia, Michigan, Gemphire Therapeutics is dedicated to addressing the needs of patients with cardiometabolic disorders. The company was acquired by NeuroBo Pharmaceuticals in a reverse merger transaction in December 2019.

Aventura intelligently orchestrates assets, people, and systems to deliver the right information at the right time based on location and credentials. It locates and re-assigns the closest online printer and uniquely manages print routing to make it easier to detect and fix printing failures. Aventura was formed in 2007 and headquartered in Denver, Colorado.

Qstream, Inc. is a software company that specializes in developing a mobile sales acceleration platform designed to enhance job proficiency and influence behavior within sales teams. Founded in 2008 and headquartered in Burlington, Massachusetts, Qstream serves clients across various sectors, including technology, financial services, and life sciences. The company operates engineering facilities in Dublin, Ireland, and Hood River, Oregon, while maintaining sales headquarters in Maidenhead, United Kingdom, and an office in San Francisco. Qstream's micro-learning platform enables organizations to manage and measure the human aspects of sales performance, providing analytics-driven insights that facilitate team excellence.

Foodsmart is a digital nutrition platform focused on enhancing health outcomes through personalized dietary recommendations. The company aims to support individuals dealing with chronic diseases and food insecurity by collaborating with health plans and healthcare providers. Its online telehealth application offers real-time guidance across various settings, including homes, workplaces, grocery stores, and restaurants. This comprehensive approach enables users to make healthier food choices and select recipes that can mitigate chronic health issues, thereby promoting overall well-being. By providing access to affordable and tailored healthy eating options, Foodsmart strives to empower individuals to improve their nutrition and health.

Aileron Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Watertown, Massachusetts, dedicated to developing innovative therapeutics, particularly stabilized cell-permeating alpha-helical peptides, for oncology and other therapeutic areas. The company’s lead product candidate, ALRN-6924, is designed to treat advanced solid tumors and is currently undergoing various clinical trials, including Phase 2a studies for peripheral T-cell lymphoma and advanced solid tumors, as well as Phase 1 trials for acute myeloid leukemia and myelodysplastic syndromes. Aileron Therapeutics also explores next-generation wild type p53 reactivators and has established collaborations with notable institutions such as Dana-Farber/Boston Children’s Cancer and Blood Disorders Center and Pfizer to evaluate the effectiveness of ALRN-6924 in combination with other treatments. Founded in 2001 and originally known as Renegade Therapeutics, the company aims to address critical cell functions through its novel approach to modulating protein-protein interactions.

Molecular Templates, Inc. is a clinical-stage biopharmaceutical company based in Austin, Texas, dedicated to the discovery and development of biologic therapeutics aimed at treating cancer and other serious diseases. The company utilizes its proprietary engineered toxin body (ETB) platform to create therapies with unique mechanisms of action that differ from traditional antibody-drug conjugates. Its lead candidate, MT-3724, is currently undergoing Phase II clinical trials for relapsed and refractory diffuse large B-cell lymphoma and non-Hodgkin’s lymphoma. Additionally, Molecular Templates is developing other candidates, including MT-4019, which targets CD38, and has a partnership with Takeda Pharmaceutical Company to create CD38-targeted therapies for multiple myeloma. The company also collaborates with Vertex Pharmaceuticals to enhance the hematopoietic stem cell transplant process through novel conditioning regimens.

Aileron Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Watertown, Massachusetts, dedicated to developing innovative therapeutics, particularly stabilized cell-permeating alpha-helical peptides, for oncology and other therapeutic areas. The company’s lead product candidate, ALRN-6924, is designed to treat advanced solid tumors and is currently undergoing various clinical trials, including Phase 2a studies for peripheral T-cell lymphoma and advanced solid tumors, as well as Phase 1 trials for acute myeloid leukemia and myelodysplastic syndromes. Aileron Therapeutics also explores next-generation wild type p53 reactivators and has established collaborations with notable institutions such as Dana-Farber/Boston Children’s Cancer and Blood Disorders Center and Pfizer to evaluate the effectiveness of ALRN-6924 in combination with other treatments. Founded in 2001 and originally known as Renegade Therapeutics, the company aims to address critical cell functions through its novel approach to modulating protein-protein interactions.

ShapeUp is a provider of corporate wellness solutions based in Providence, Rhode Island. Founded in 2006, the company utilizes a social networking platform to promote employee health and wellness through incentives and gamification. ShapeUp's programs are clinically proven and have reached over 2 million individuals, serving more than 500 employers and health plans across 109 countries. The company's approach focuses on driving positive health outcomes for large populations by integrating social interaction and financial rewards into its wellness initiatives.

PathoGenetiX is developing an automated system for the rapid identification of pathogenic bacterial strains using proprietary Genome Sequence Scanning Technology. The company's approach, which employs a single reagent set to generate genomic bar codes based on bacterial DNA, can cost-effectively identify thousands of strains in a single test from complex samples in three hours. PathoGenetiX is developing its GSS platform for use in genomics research, food and product safety testing, and clinical infectious disease diagnostics, with the initial commercial introduction into the research market planned for 2012.

Molecular Templates, Inc. is a clinical-stage biopharmaceutical company based in Austin, Texas, dedicated to the discovery and development of biologic therapeutics aimed at treating cancer and other serious diseases. The company utilizes its proprietary engineered toxin body (ETB) platform to create therapies with unique mechanisms of action that differ from traditional antibody-drug conjugates. Its lead candidate, MT-3724, is currently undergoing Phase II clinical trials for relapsed and refractory diffuse large B-cell lymphoma and non-Hodgkin’s lymphoma. Additionally, Molecular Templates is developing other candidates, including MT-4019, which targets CD38, and has a partnership with Takeda Pharmaceutical Company to create CD38-targeted therapies for multiple myeloma. The company also collaborates with Vertex Pharmaceuticals to enhance the hematopoietic stem cell transplant process through novel conditioning regimens.

Aventura intelligently orchestrates assets, people, and systems to deliver the right information at the right time based on location and credentials. It locates and re-assigns the closest online printer and uniquely manages print routing to make it easier to detect and fix printing failures. Aventura was formed in 2007 and headquartered in Denver, Colorado.

ClearDATA Networks, Inc. specializes in providing cloud computing and information security solutions tailored for the healthcare sector, serving healthcare providers, life sciences organizations, and payers. Established in 2009 and headquartered in Austin, Texas, the company offers a comprehensive multi-cloud platform that automates, protects, and manages healthcare applications and data. Its key products include ClearDATA Comply, a software solution for maintaining healthcare cloud compliance, and ClearDATA Assess, which aids in conducting mandatory HIPAA Security Risk Assessments. Additionally, ClearDATA Locate Mask allows organizations to utilize unstructured datasets while safeguarding sensitive information. The company is recognized for its HITRUST-certified cloud services, which ensure robust data privacy protections and extensive compliance capabilities, helping healthcare organizations leverage data effectively while enhancing operational efficiency.

Aileron Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Watertown, Massachusetts, dedicated to developing innovative therapeutics, particularly stabilized cell-permeating alpha-helical peptides, for oncology and other therapeutic areas. The company’s lead product candidate, ALRN-6924, is designed to treat advanced solid tumors and is currently undergoing various clinical trials, including Phase 2a studies for peripheral T-cell lymphoma and advanced solid tumors, as well as Phase 1 trials for acute myeloid leukemia and myelodysplastic syndromes. Aileron Therapeutics also explores next-generation wild type p53 reactivators and has established collaborations with notable institutions such as Dana-Farber/Boston Children’s Cancer and Blood Disorders Center and Pfizer to evaluate the effectiveness of ALRN-6924 in combination with other treatments. Founded in 2001 and originally known as Renegade Therapeutics, the company aims to address critical cell functions through its novel approach to modulating protein-protein interactions.

Activate Networks, Inc. is a network analytics company that specializes in identifying and understanding the social connections that influence commercial, organizational, and health outcomes. The company offers a suite of analytics products and software designed to help organizations leverage the social networks of their customers, prospects, voters, and employees, utilizing existing data within the organization. Activate Networks employs its proprietary RealConnect™ platform to map, analyze, and activate networks across various sectors, including healthcare, technology, political campaigns, and professional services. By providing unique, actionable insights, Activate Networks directly impacts marketing campaigns, health behavior change initiatives, talent management, and innovation efforts.

Cleveland HeartLab, Inc. is a specialty clinical laboratory dedicated to the prevention and management of cardiovascular disease (CVD). The company specializes in novel biomarker technologies and develops proprietary diagnostic tests aimed at improving the early identification of individuals at risk for CVD. Cleveland HeartLab offers a range of clinical laboratory services, including an inflammatory panel for CVD, advanced CVD risk profiles, and lipid panels. By focusing on innovative molecular biomarker technologies, the company seeks to enhance the management and reduction of inflammation, ultimately contributing to better cardiovascular health outcomes.

IlluminOss Medical, Inc., established in 2007 and headquartered in East Providence, Rhode Island, is a medical device company specializing in orthopedic fracture repair. It designs, develops, and markets products based on its proprietary IlluminOss System, which employs a light-curable polymer within an expandable balloon catheter to create patient-specific intramedullary implants for bone stabilization. This minimally invasive technology is particularly suited for treating osteoporotic and compromised bone. The company's products are CE-marked and FDA-cleared for various anatomical sites and are distributed in several European countries.

PathoGenetiX is developing an automated system for the rapid identification of pathogenic bacterial strains using proprietary Genome Sequence Scanning Technology. The company's approach, which employs a single reagent set to generate genomic bar codes based on bacterial DNA, can cost-effectively identify thousands of strains in a single test from complex samples in three hours. PathoGenetiX is developing its GSS platform for use in genomics research, food and product safety testing, and clinical infectious disease diagnostics, with the initial commercial introduction into the research market planned for 2012.

MedVentive is a technology solutions provider specializing in healthcare delivery systems, payers, and employer coalitions. Founded in 1997 by physicians, the company focuses on developing innovative solutions aimed at enhancing the quality of care while reducing associated costs. MedVentive's offerings include quality management, clinical integration, pharmacy management, and point-of-care decision support. Additionally, the company provides a pay-for-performance solution that calculates and tracks clinical measures, delivering tailored patient intervention recommendations. Through these services, MedVentive enables physician groups and integrated delivery systems to implement meaningful changes in their healthcare practices.

Aventura intelligently orchestrates assets, people, and systems to deliver the right information at the right time based on location and credentials. It locates and re-assigns the closest online printer and uniquely manages print routing to make it easier to detect and fix printing failures. Aventura was formed in 2007 and headquartered in Denver, Colorado.

Lantos Technologies, Inc., established in 2009 and headquartered in Derry, New Hampshire, specializes in developing advanced 3D digital ear scanning technology. The company offers the FDA-cleared AURA system, which captures comprehensive data from the outer ear to deep within the ear canal, enabling designers to create personalized in-ear devices with superior comfort and sound quality. This includes custom in-ear headphones, musicians' monitors, hearing aids, and noise protection solutions. Lantos' technology enhances clinical efficiency for audiologists by providing precise measurements, improving patient outcomes, and streamlining the process for faster turnaround times on custom devices.

Cleveland HeartLab, Inc. is a specialty clinical laboratory dedicated to the prevention and management of cardiovascular disease (CVD). The company specializes in novel biomarker technologies and develops proprietary diagnostic tests aimed at improving the early identification of individuals at risk for CVD. Cleveland HeartLab offers a range of clinical laboratory services, including an inflammatory panel for CVD, advanced CVD risk profiles, and lipid panels. By focusing on innovative molecular biomarker technologies, the company seeks to enhance the management and reduction of inflammation, ultimately contributing to better cardiovascular health outcomes.

PathoGenetiX is developing an automated system for the rapid identification of pathogenic bacterial strains using proprietary Genome Sequence Scanning Technology. The company's approach, which employs a single reagent set to generate genomic bar codes based on bacterial DNA, can cost-effectively identify thousands of strains in a single test from complex samples in three hours. PathoGenetiX is developing its GSS platform for use in genomics research, food and product safety testing, and clinical infectious disease diagnostics, with the initial commercial introduction into the research market planned for 2012.

NanoMR is a manufacturer of blood diagnostic devices that has pioneered a system for the rapid isolation of rare cells from complex biological samples at concentrations as low as one cell per milliliter. Utilizing an innovative immunomagnetic capture technology, the company can simultaneously target multiple cell types, enabling the efficient extraction of pathogens, such as bacteria and fungi from bloodstream infections, as well as specific cells like circulating tumor cells and fetal cells. This advanced system can achieve results in less than 30 minutes, significantly improving the speed and accuracy of diagnostics in various medical applications.

SpringLeaf Therapeutics (formerly known as Entra Pharmaceuticals, Inc.) is creating innovative therapeutic modalities to address serious disease and elevate the quality of care for patients. SpringLeaf's technology is based on convergent science and is designed to enable and differentiate therapeutics. SpringLeaf was founded based on breakthrough science at MIT and is backed by leading investors including Flybridge Capital Partners and North Bridge Venture Partners.

Catch.com (formerly Snaptic) is a market leader for Android smartphones and tablets. Millions have downloaded our mobile apps, including Catch Notes, AK Notepad and Compass. Our mobile apps also run on iOS and the web, and we are just getting started. Catch.com was founded in 2008 and is on the cusp of a seismic shift driven by growth in smartphone use -- reinventing how people interact, collaborate and discover what’s important to them.

Lantos Technologies, Inc., established in 2009 and headquartered in Derry, New Hampshire, specializes in developing advanced 3D digital ear scanning technology. The company offers the FDA-cleared AURA system, which captures comprehensive data from the outer ear to deep within the ear canal, enabling designers to create personalized in-ear devices with superior comfort and sound quality. This includes custom in-ear headphones, musicians' monitors, hearing aids, and noise protection solutions. Lantos' technology enhances clinical efficiency for audiologists by providing precise measurements, improving patient outcomes, and streamlining the process for faster turnaround times on custom devices.

ShapeUp is a provider of corporate wellness solutions based in Providence, Rhode Island. Founded in 2006, the company utilizes a social networking platform to promote employee health and wellness through incentives and gamification. ShapeUp's programs are clinically proven and have reached over 2 million individuals, serving more than 500 employers and health plans across 109 countries. The company's approach focuses on driving positive health outcomes for large populations by integrating social interaction and financial rewards into its wellness initiatives.

Viridos is a company that develops and commercializes genomic-driven solutions aimed at tackling global energy and environmental issues. It specializes in synthesizing and programming DNA to create and utilize technologies in synthetic genomics. The company designs and develops microbes for various industrial processes and environmental applications, including microbial cultivation technologies that identify novel microorganisms and new genes. Additionally, Viridos focuses on enhancing biofuel production, utilizing photosynthetic organisms to generate value-added products from sunlight and carbon dioxide, and improving the recovery rates of subsurface hydrocarbons. Its innovations also extend to the development of high-yield, disease-resistant feedstocks. Through these efforts, Viridos contributes to the production of energy, chemicals, and pharmaceuticals, while also promoting carbon sequestration and environmental remediation.

Catch.com (formerly Snaptic) is a market leader for Android smartphones and tablets. Millions have downloaded our mobile apps, including Catch Notes, AK Notepad and Compass. Our mobile apps also run on iOS and the web, and we are just getting started. Catch.com was founded in 2008 and is on the cusp of a seismic shift driven by growth in smartphone use -- reinventing how people interact, collaborate and discover what’s important to them.

Tetraphase Pharmaceuticals, Inc. is a biopharmaceutical company focused on the creation, development, and commercialization of innovative antibiotics aimed at treating serious and life-threatening multidrug-resistant infections. The company's primary product, Xerava, is a synthetic fluorocycline administered intravenously, designed as a first-line empiric monotherapy for multidrug-resistant infections, particularly those caused by MDR Gram-negative bacteria. Tetraphase has successfully conducted Phase III clinical trials for Xerava, specifically targeting complicated intra-abdominal infections. In addition to Xerava, the company is developing several other candidates, including TP-271 for respiratory diseases linked to bacterial biothreats and TP-6076 for MDR Gram-negative infections, both in Phase I clinical trials. Furthermore, TP-2846 is being explored as a treatment for acute myeloid leukemia. Tetraphase Pharmaceuticals has established a licensing agreement with Everest Medicines Limited to enhance the development and commercialization of Xerava in select regions across Asia. Founded in 2006 and headquartered in Watertown, Massachusetts, Tetraphase operates as a subsidiary of La Jolla Pharmaceutical Company.

IntraPace, Inc. is a medical device company focused on developing innovative solutions for obesity treatment. Founded in 2001 and headquartered in Mountain View, California, the company has created the abiliti system, an implantable device that stimulates a satiety response to assist patients in achieving weight loss. This device utilizes established technology similar to that found in cardiac pacemakers and defibrillators. The abiliti system is designed for implantation using standard laparoscopic techniques, allowing for a minimally invasive procedure that does not alter the anatomy of the digestive system or restrict dietary choices.

TransMedics Group, Inc., established in 1998 and based in Andover, Massachusetts, is a commercial-stage medical technology company specializing in transforming organ transplant therapy for end-stage organ failure patients worldwide. The company's core product, the Organ Care System (OCS), is a portable, innovative technology that maintains donor organs outside the body in a near-physiologic state, replicating human-like conditions. This system includes OCS LUNG and OCS Heart, designed to preserve and optimize lungs and hearts respectively during transport, allowing for better assessment and improvement of organ condition. TransMedics also offers clinical services to enhance transplant volume, improve outcomes, and reduce learning curves for healthcare providers.

Saladax Biomedical, Inc. is a precision medicine company based in Bethlehem, Pennsylvania, focused on developing and commercializing diagnostic blood tests that enhance personalized medicine. The company offers a range of products aimed at optimizing drug therapy in psychiatry and oncology. Its MyCare product line includes tests such as MyCare Psychiatry, which helps determine appropriate antipsychotic dosages; MyCare Oncology, which focuses on chemotherapy exposure optimization; and MyCare Neurology for assessing neurological drug effects. Key tests include My5-FU, MyPaclitaxel, MyDocetaxel, and MyImatinib, which are designed to tailor chemotherapy treatments for various cancers. Saladax Biomedical markets its diagnostic solutions to healthcare providers worldwide through both distributors and direct sales, striving to empower physicians to deliver personalized care by ensuring optimal drug dosing. The company has been providing innovative diagnostic solutions for over 15 years.

Biocius Life Sciences, Inc. is a company specializing in drug discovery research, established in 2009 and located in Woburn, Massachusetts. As a subsidiary of BioTrove, Inc., Biocius develops advanced technologies, including high-throughput mass spectrometry systems, to facilitate the drug discovery process. The company's innovative approach aims to enhance efficiency and accuracy in identifying potential therapeutic compounds, contributing to advancements in pharmaceutical research and development.

Virgin Pulse, a subsidiary of Sir Richard Branson's Virgin Group, focuses on developing technology that promotes healthy lifestyle habits among employees. By tailoring its solutions to align with organizational culture, Virgin Pulse enhances the overall well-being experience for users, leading to improved outcomes for both employees and businesses. The brand, established in 1970, is recognized for its commitment to creating exceptional consumer experiences through innovation and quality service. Virgin Pulse aims to foster engagement and support within workplaces, contributing to a healthier workforce and a more productive environment.

MedVentive is a technology solutions provider specializing in healthcare delivery systems, payers, and employer coalitions. Founded in 1997 by physicians, the company focuses on developing innovative solutions aimed at enhancing the quality of care while reducing associated costs. MedVentive's offerings include quality management, clinical integration, pharmacy management, and point-of-care decision support. Additionally, the company provides a pay-for-performance solution that calculates and tracks clinical measures, delivering tailored patient intervention recommendations. Through these services, MedVentive enables physician groups and integrated delivery systems to implement meaningful changes in their healthcare practices.

Exact Sciences Corporation, based in Madison, Wisconsin, specializes in cancer screening and diagnostic tests. Its primary product, Cologuard, is a non-invasive, stool-based DNA test for detecting colorectal cancer and pre-cancer. The company also offers Oncotype DX, a suite of tissue-based genomic tests for breast and colon cancer, and OncoExTra, a liquid-based comprehensive genomic profiling test. Exact Sciences is committed to improving cancer detection and treatment through innovative, patient-friendly solutions.

Aileron Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Watertown, Massachusetts, dedicated to developing innovative therapeutics, particularly stabilized cell-permeating alpha-helical peptides, for oncology and other therapeutic areas. The company’s lead product candidate, ALRN-6924, is designed to treat advanced solid tumors and is currently undergoing various clinical trials, including Phase 2a studies for peripheral T-cell lymphoma and advanced solid tumors, as well as Phase 1 trials for acute myeloid leukemia and myelodysplastic syndromes. Aileron Therapeutics also explores next-generation wild type p53 reactivators and has established collaborations with notable institutions such as Dana-Farber/Boston Children’s Cancer and Blood Disorders Center and Pfizer to evaluate the effectiveness of ALRN-6924 in combination with other treatments. Founded in 2001 and originally known as Renegade Therapeutics, the company aims to address critical cell functions through its novel approach to modulating protein-protein interactions.

BioTrove, Inc. specializes in micro and nano-scale technology platforms designed for life science research and drug discovery. The company offers several key products, including OpenArray, which facilitates relative gene expression analysis and supports genomic research across various fields such as agriculture, disease research, and public health. Additionally, BioTrove provides the RapidFire platform, enabling the screening of difficult drug targets through mass spectrometry-based assay development, along with the RapidFire mass spectrometry hardware system, which serves as a detection technology for drug screening and in vitro ADME applications. Their innovative systems consist of laboratory instruments and consumables that enhance the efficiency of genomic analysis, high-throughput screening, and molecular diagnostics, thereby accelerating research processes and development across multiple scientific domains.

Xcellerex is a biomanufacturing technology provider based in Marlborough, Massachusetts, founded in 2002 by Parrish M. Galliher. The company specializes in the development and production of innovative biomanufacturing systems and production-scale bioreactors that enhance the efficiency and cost-effectiveness of producing therapeutic proteins, including biosimilars and vaccines. Xcellerex's proprietary solutions, including the FlexFactory®, feature modular and portable production trains utilizing single-use technologies, advanced process automation, and compact cleanroom designs, offering advantages such as faster installation, lower capital investment, and reduced risk of cross-contamination. The company also offers contract services for process development and manufacturing of biopharmaceuticals, including its PDMax platform for process optimization and the development of vaccines, such as an inactivated virus vaccine for yellow fever.

Carefx is a provider of information technology solutions tailored for healthcare organizations in North America and Europe. The company's primary offering, Fusionfx, is a suite of interoperable workflow and analytics solutions designed to streamline clinical and business processes. Fusionfx synthesizes disparate data into clinically relevant, user-centric workflows, facilitating better communication between hospital and integrated delivery network executives, healthcare IT departments, and care providers. This solution enables stakeholders, including patients, payers, clinicians, and compliance agencies, to access comprehensive and understandable information, thus enhancing accountability and transparency in operations.

Skylight Healthcare Systems, Inc. specializes in providing interactive patient care system technology for hospitals and healthcare administrators. The company operates the ACCESS interactive patient system, a two-way digital communications platform that transforms hospital television sets into comprehensive information, communication, education, and entertainment networks. This system enables patients to access essential information about their hospital stay, request assistance from support departments, view on-demand health education, provide real-time feedback through surveys, and enjoy various entertainment options. Additionally, Skylight offers iCarePassport, a web-based patient care and outcomes system designed to enhance ongoing patient engagement by facilitating personalized communication throughout the continuum of care. Founded in 1999 and headquartered in San Diego, California, Skylight Healthcare Systems addresses the critical needs of patients in education, health literacy, and access to services, thereby improving the overall healthcare experience.

IPC is the nation's leading national physician group practice focused on the delivery of hospital medicine and related facility-based services. IPC providers manage the care of patients in coordination with primary care physicians and specialists in over 1,100 facilities in 28 states across the U.S. We provide care to over 1 million patients annually while maintaining high standards of quality care, aligning with the mission and objectives of the facilities where we serve.

ForHealth Technologies is a company dedicated to developing automation technology solutions specifically for the intravenous drug preparation process. Founded in 1998 and headquartered in Daytona Beach, Florida, the company has a focus on enhancing the efficiency and safety of drug preparation in healthcare settings. In March 2009, ForHealth Technologies was acquired by Baxa Corporation, further expanding its reach and capabilities within the medical technology sector.

Passport Health Communications, Inc. is a software-as-a-service company specializing in revenue cycle management solutions for healthcare organizations, including hospitals, physician offices, and outpatient centers in the United States. The company offers a comprehensive suite of tools designed to streamline various aspects of the revenue cycle. Key products include the eCare Patient Access Suite, which facilitates patient demographic and insurance verification, compliance, and payment management; OrderChecker for validating outpatient diagnosis and procedure codes; and IntelliSource, an integrated system for patient access. Other offerings include the Patient Payment Estimator, eCashiering for processing payments, and a Claims Management Suite for claims submission and reimbursement. Passport Health Communications also provides automation solutions such as BatchSource, which enhances transaction processing. With a focus on improving efficiency and compliance, the company helps healthcare providers manage patient payments and insurance eligibility, thereby supporting effective financial operations in the healthcare sector. Founded in 1996 and headquartered in Franklin, Tennessee, the company was formerly known as InterMed, LLC before rebranding in 1998.

Virscio is a biotechnology company based in Hamden, Connecticut, focused on developing therapeutics for central nervous system disorders, including neurodegeneration, memory loss, and obesity. The company employs its proprietary PrimaTox platform, a predictive toxicogenomics tool, to enhance the selection and preclinical validation of pharmaceutical candidates. Virscio specializes in translational research and development, offering a variety of preclinical studies and research programs across multiple therapeutic areas. This approach enables collaborations with pharmaceutical, biotechnology, and academic organizations to minimize the risk of clinical failures in drug development.

Emageon is a provider of enterprise-level information technology solutions focused on the clinical analysis and management of digital medical images within healthcare organizations. The company specializes in developing software products that enable physicians and healthcare professionals to efficiently manage, access, and visualize multi-specialty medical content. Emageon's offerings include advanced visualization tools, clinical content management systems, and workflow solutions designed to enhance the efficiency and effectiveness of medical imaging processes in various healthcare settings.

CareMedic Systems, Inc. is a provider of revenue cycle management solutions for hospitals and healthcare providers in the United States and Puerto Rico. Founded in 1996 and headquartered in St. Petersburg, Florida, with additional offices in Alpharetta and Decatur, Georgia, the company offers a range of products designed to optimize financial operations. Its key offerings include electronic Financial Record for healthcare financial management, VerifyAR for document management and eligibility verification, and AccelerateAR for Medicare review and claims submission. Additionally, CareMedic Systems provides OptimizeAR for payment management, ImageAR for document scanning and storage, and ResolveAR for accounts receivables outsourcing and credit balance resolution. These solutions are delivered through an application service provider model, enabling clients to streamline cash flow and improve reimbursement processes.

Zonare Medical Systems, Inc. specializes in the development, manufacturing, and commercialization of compact ultrasound systems designed for diagnostic imaging across various clinical applications. The company's flagship product, the z.one ultrasound system, utilizes its proprietary Zone Sonography technology, which enhances data acquisition and image formation, allowing customers to maintain the system while adding new clinical applications and advanced imaging capabilities. Zonare Medical Systems sells its products through a direct sales force in the United States and a combination of distributors and direct sales representatives in approximately 40 international markets. Founded in 1999 and headquartered in Mountain View, California, the company was previously known as NovaSonics, Inc.