Atalanta Therapeutics
Series B in 2025
Atalanta Therapeutics is a biotechnology company developing targeted RNA-modulating therapeutics for treating genetically defined diseases. It utilizes proprietary structure-switching molecules to modulate gene expression, focusing on oncology, neurology, and rare genetic disorders.
Eleos Health
Series C in 2025
Eleos Health offers automated healthcare technology solutions. Its AI-powered Speech-to-Insights system aids clinicians in making decisions swiftly, ensuring personalized, efficient, and cost-effective patient care.
Lighthouse
Series C in 2024
Lighthouse is a commercial platform tailored for the travel and hospitality industry, specializing in hotel management solutions. The company offers a cloud-based platform that visualizes and leverages data to enhance business success. By providing actionable market insights and business intelligence tools, Lighthouse enables hoteliers and hotel management companies to make informed revenue and distribution decisions. Its services include real-time data analytics, which empower users to maximize property occupancy rates and increase revenue and profit. Formerly known as OTA Insight, Lighthouse aims to transform complex market dynamics into manageable strategies that foster growth in the hospitality sector.
Founded in 2014 by Stanford University Biodesign Fellows collaborating with leading urologists, Zenflow develops a novel spring device to alleviate permanent benign prostatic hyperplasia (BPH) symptoms in men. Its minimally invasive solution preserves natural anatomy and improves patient experience.
Notabene, Inc. is a New York-based company founded in 2020 that specializes in developing a software as a service (SaaS) platform for crypto compliance tailored for the financial industry. The company focuses on helping financial institutions adhere to emerging global regulations concerning cryptocurrency transactions, specifically addressing the complexities of the Travel Rule. Notabene offers a unified API and dashboard designed to assist compliance officers in managing risk associated with both Travel Rule and non-custodial transactions. By providing access to a broad network of crypto businesses, Notabene simplifies the compliance process, enhances transaction confidence, and ultimately supports its clients in increasing their transaction volumes and business growth.
Based on our deep science and focused on patients in need.
Spry is a digital health platform that enables movement health professionals to collect and analyze patient data in real time. By leveraging machine learning and artificial intelligence, the platform provides personalized protocols based on evidence-based practices and standards of care. This allows practitioners and owners of physical therapy centers to effectively manage both clinical and administrative functions, enhancing the quality of patient care and operational efficiency.
Canoe Software Inc. provides a sophisticated software solution focused on financial document and data management. Founded in 2013 and based in New York, the company specializes in automating the extraction and organization of investment documents using artificial intelligence and machine learning technologies. This enables users to efficiently convert unstructured data from various formats, such as PDFs, into actionable insights, thereby improving operational efficiency. Canoe's platform supports a wide range of clients, including single and multi-family offices, endowments, foundations, pensions, investment consultants, and financial institutions, facilitating better management of post-investment operations, monitoring, and reporting. By streamlining the data management process, Canoe helps minimize manual data entry and enhances the accuracy of financial reporting and analysis.
Odaseva is a company specializing in data management solutions for large enterprises utilizing Salesforce. It offers a comprehensive cloud-based platform that focuses on data protection, privacy, and governance. The Odaseva Enterprise Data Security Platform is designed to ensure the confidentiality, integrity, and availability of critical business information by providing integrated security products and services. Key features of the platform include backup and recovery, archiving, monitoring of governor limits, and compliance support for regulations such as GDPR. By enabling businesses to take full control of their data, Odaseva helps eliminate risks and facilitates confident digital transformation.
Canary Technologies
Series C in 2024
Canary Technologies is a hospitality technology company that modernizes hotel operations. It offers a guest management platform featuring contactless check-in, digital authorizations, and an amenity store. The platform drives revenue growth, improves staff productivity, ensures compliance, and reduces fraud.
Ashby is a developer of recruitment software tailored for high-growth companies. The company creates enterprise-grade employment solutions designed to enhance the hiring processes of organizations. Its platform enables company leaders, recruiters, and hiring managers to streamline their recruitment efforts, thereby improving overall efficiency and productivity. Ashby's software is accessible for teams of various sizes, allowing them to effectively meet their hiring objectives while fostering organizational growth.
Expressable
Series B in 2024
Expressable is an online speech therapy practice dedicated to enhancing communication for individuals with speech and language disorders. It employs a parent-focused care model that integrates technology and educational resources, allowing families to incorporate speech therapy techniques into their daily routines. The platform offers a range of services, including support for accent modification, aphasia, apraxia of speech, autism spectrum disorder, and various language disorders. By providing tailored weekly practice activities, Expressable aims to improve speech and language outcomes for both children and adults, ensuring a more effective and accessible therapy experience.
Quantum Circuits
Venture Round in 2024
Founded in 2015 by Dr. Robert Schoelkopf, Quantum Circuits develops and manufactures quantum computers based on superconducting devices. The company focuses on creating full-stack quantum computers designed for efficient scaling, with a pioneering approach to error detection and correction.
Engrail Therapeutics
Series B in 2024
Founded in 2019, Engrail Therapeutics is dedicated to developing and commercializing neuro drugs. Its primary focus is on treating diseases related to the nervous system. The company's flagship compound, ENX-101, is a preclinical modulator of a receptor for GABA, a neurotransmitter in the brain.
HiLabs is a developer of a healthcare data mining platform that aims to enhance data-driven decision-making within healthcare organizations. By leveraging artificial intelligence, HiLabs empowers employees to explore their data intuitively, uncover novel insights, and interact with data visualizations. The platform allows users to customize dashboards and generate new attributes, thus enhancing their ability to understand and utilize client health data effectively. HiLabs recognizes that healthcare providers possess vital domain knowledge but often lack the necessary tools to extract meaningful insights from their data. Through its innovative solutions, HiLabs bridges this gap, enabling healthcare organizations to harness their data more efficiently and improve overall decision-making processes.
Nocion Therapeutics
Series B in 2024
Nocion Therapeutics is a biopharmaceutical company developing novel therapies called 'nocions' that selectively target actively firing nociceptors to provide relief for serious conditions such as cough, itch, pain, and inflammation.
Comanche Biopharma
Series B in 2024
Comanche is a biopharmaceutical company developing an investigational siRNA medicine for preterm preeclampsia. Its mission is to provide safe, effective, evidence-based, and affordable therapies for treating life-threatening complications of pregnancy.
Burro is a developer of an autonomous farming platform designed to enhance productivity in agricultural and outdoor settings. The company creates robotic tools that autonomously follow workers and transport cargo, alleviating the physical burden of labor-intensive tasks. By automating these processes, Burro allows farmworkers to concentrate on more value-added activities. Additionally, the company's technology captures essential data that aids in further automating farm operations, ultimately aiming to streamline all tedious agricultural tasks. This focus on operational efficiency not only supports farmers in improving their workflows but also fosters growth within the sector.
Founded in 2014, Genomics develops algorithms and software solutions focused on cancer, microbes, and rare diseases. Its solutions empower governments, healthcare providers, pharmaceutical companies, clinicians, and researchers to improve diagnoses, treatment options, and drug development processes through accurate genomic data analysis.
Eleos Health
Series B in 2023
Eleos Health offers automated healthcare technology solutions. Its AI-powered Speech-to-Insights system aids clinicians in making decisions swiftly, ensuring personalized, efficient, and cost-effective patient care.
Doceree is a healthcare marketing technology company that provides a platform and solutions to help pharmaceutical and healthcare brands reach healthcare professionals. Its programmatic platform supports physician engagement and targeted advertising across physician networks, medical journals, telemedicine platforms, and relevant digital channels, delivering compliant, scalable messages. The platform uses artificial intelligence, data segmentation, and analytics to identify target healthcare professionals and optimize reach across global digital ecosystems. Doceree serves pharmaceutical brands, medical device brands, consumer health brands, hospitals, and media agencies, enabling access to physician-only environments and enabling compliant engagement at scale.
Better Life Partners
Series B in 2023
Better Life Partners Inc. is a healthcare company based in Hanover, New Hampshire, dedicated to providing comprehensive support for individuals struggling with opioid use disorder in the United States. Established in 2018, the company offers a range of services, including medication-assisted treatment, counseling, peer coaching, and group sessions. Better Life Partners focuses on delivering personalized healthcare to vulnerable populations, utilizing technology to create customizable care plans that ensure effective and reliable service delivery. By integrating medical and behavioral healthcare, the company addresses the needs of those affected by addiction, facilitating their recovery through a combination of telehealth, community-based support, and innovative care approaches. With additional offices across New Hampshire, Better Life Partners aims to make a meaningful impact on the lives of individuals seeking to overcome substance abuse challenges.
K36 Therapeutics
Series B in 2023
K36 Therapeutics develops small molecule therapeutics for cancer treatment. It translates epigenetic modulation of oncogenic pathways into small molecule therapies.
Founded in 2014, Tradier operates a cloud-based financial services platform. It offers APIs, modules, and tools for platform providers, developers, and investors, enabling improved trade execution, real-time market data access, and transparent pricing.
1upHealth
Series C in 2023
Founded in 2017, 1upHealth operates a health data aggregation platform that securely centralizes patient records from various electronic medical systems. Its platform enables patients to control and share their consolidated digital health record with providers, while also allowing developers to access clinical data from connected clinics and hospitals.
Bicara Therapeutics
Series B in 2023
Bicara Therapeutics is a clinical-stage biopharmaceutical company focused on developing innovative bifunctional therapies for patients with solid tumors. The company's lead program, ficerafusp alfa, is a bifunctional antibody that integrates two clinically validated targets: a monoclonal antibody aimed at the epidermal growth factor receptor (EGFR) and a domain that binds to human transforming growth factor beta (TGF-β). This dual-action approach is designed to deliver an immunomodulatory payload directly to the tumor microenvironment, enhancing immune cell activity in cancer patients and potentially providing long-term therapeutic efficacy.
Cadence Neuroscience
Venture Round in 2023
Cadence Neuroscience develops implantable medical device therapies for epilepsy, central pain, and other neurological disorders. Founded in 2017 and based in Redmond, Washington, the company pursues core technology developed at Mayo Clinic that is being evaluated clinically. The device detects brain signals and delivers electrical stimulation to modulate neural circuits, enabling personalized brain stimulation to improve seizure control relative to existing protocols.
Canoe Software Inc. provides a sophisticated software solution focused on financial document and data management. Founded in 2013 and based in New York, the company specializes in automating the extraction and organization of investment documents using artificial intelligence and machine learning technologies. This enables users to efficiently convert unstructured data from various formats, such as PDFs, into actionable insights, thereby improving operational efficiency. Canoe's platform supports a wide range of clients, including single and multi-family offices, endowments, foundations, pensions, investment consultants, and financial institutions, facilitating better management of post-investment operations, monitoring, and reporting. By streamlining the data management process, Canoe helps minimize manual data entry and enhances the accuracy of financial reporting and analysis.
NOCD Inc. is a Chicago-based company founded in 2014 that specializes in developing a mobile application aimed at assisting individuals with obsessive-compulsive disorder (OCD). The platform connects users to licensed therapists who specialize in OCD through face-to-face video therapy sessions. Utilizing cognitive behavioral therapy techniques, the application guides users in self-treatment and monitoring of their symptoms, offering tools for exposure and response prevention exercises. In addition to therapy sessions, NOCD provides 24/7 support via self-help resources and peer communities, facilitating ongoing care and enabling patients to manage their condition effectively. The company focuses on improving treatment outcomes for OCD through its innovative online platform.
Ensoma is a biotechnology company focused on advancing genomic medicine through its innovative in vivo approach, utilizing proprietary Engenious vectors. These vectors are engineered to deliver a wide array of gene modification technologies directly to blood and immune cells, including T cells, B cells, and myeloid cells, without the necessity for stem cell collection or prior myeloablative conditioning, which can pose risks to patients. This unique method allows for the administration of therapies via a single injection, enhancing accessibility and convenience in various healthcare settings, even where resources may be limited. Ensoma aims to expand the curative potential of genomic medicine, making it more accessible to patients in need.
Pulmocide
Series C in 2022
Founded in London in 2007, Pulmocide specializes in developing inhaled medicines targeting serious viral and fungal respiratory infections. Its focus is on creating drugs optimized for lung delivery to maximize efficacy while minimizing systemic exposure.
ABK Biomedical
Series C in 2022
Founded in 2012, ABK Biomedical specializes in developing embolotherapeutic products for treating hypervascular tumors. Its primary focus is improving treatment options for patients through innovative microsphere technology.
Canary Technologies
Series B in 2022
Canary Technologies is a hospitality technology company that modernizes hotel operations. It offers a guest management platform featuring contactless check-in, digital authorizations, and an amenity store. The platform drives revenue growth, improves staff productivity, ensures compliance, and reduces fraud.
Neumora Therapeutics
Series B in 2022
Neumora Therapeutics is a clinical-stage biotechnology company focused on developing precision medicines for brain diseases by combining data science with neuroscience. Founded to address the global brain disease crisis, Neumora takes an innovative approach to treatment development. The company has established a robust therapeutic pipeline that includes seven clinical and preclinical neuroscience programs targeting novel mechanisms of action for various underserved neuropsychiatric and neurodegenerative disorders. Neumora plans to advance its pipeline further by initiating multiple clinical trials across its programs in the upcoming 12 to 18 months.
Hone
Venture Round in 2022
Hone Group Inc., established in 2018, is a San Francisco-based company that specializes in live online leadership and management training. It offers a development platform that empowers organizations to enhance their employees' soft skills, including communication, team building, and conflict management. Hone's platform facilitates expert-led small group training, peer learning, and continuous reinforcement, while also providing data-driven insights to measure and improve training impact.
Founded in 2019, Vendr is a SaaS-based platform that streamlines software procurement for businesses. It offers services such as commercial negotiations, renewal management, and contract logistics to help companies efficiently manage their software purchases.
Proximie is a health technology company that enables surgeons worldwide to collaborate remotely using augmented reality, artificial intelligence, and machine learning. Its platform allows surgeons to visually guide complex surgeries, democratizing access to advanced surgical knowledge.
Invetx, Inc. is a biotechnology company based in Boston, Massachusetts, specializing in the development of protein-based therapeutics for animal health care and veterinary medicine. The company employs a team of veterinary scientists and clinicians dedicated to the discovery and development of biotherapeutics for both pets and farm animals. Invetx aims to transform the animal health industry by leveraging biopharmaceutical technologies to improve health outcomes significantly. By combining deep expertise in veterinary science with innovative therapeutic solutions, Invetx seeks to advance the future of animal care, providing effective treatments that cater to the needs of various animal populations.
Ashby is a developer of recruitment software tailored for high-growth companies. The company creates enterprise-grade employment solutions designed to enhance the hiring processes of organizations. Its platform enables company leaders, recruiters, and hiring managers to streamline their recruitment efforts, thereby improving overall efficiency and productivity. Ashby's software is accessible for teams of various sizes, allowing them to effectively meet their hiring objectives while fostering organizational growth.
RightHand Robotics
Series C in 2022
RightHand Robotics, Inc. is a manufacturer of robotic order-picking systems that streamline supply chain logistics for various industries, including e-commerce, food handling, and flexible manufacturing. Founded in 2015 and headquartered in Cambridge, Massachusetts, the company specializes in robotic solutions that automatically grasp a wide variety of items from bins and cases. Its flagship products include the ReFlex SF, which features a 3D-printed palm equipped with servos and compliant fingers, and the ReFlex TakkTile, a tactile sensor designed to enhance the robots' ability to handle items gently and correct errors. RightHand Robotics focuses on providing end-to-end solutions that simplify integration and adaptation to diverse customer workflows, ultimately reducing the costs associated with order fulfillment across sectors such as electronics, apparel, grocery, and pharmaceuticals.
Equip Health
Series B in 2022
Equip is a virtual program helping families recover from eating disorders at home with comprehensive, gold-standard care created by experts in the field and people in recovery. Equip’s five-person care teams include dieticians, physicians, therapists, and mentors who deliver wrap-around support to provide families progress and lasting recovery.
Kristina Saffran and Erin Parks co-founded the company in San Diego, California in 2019.
Logixboard
Series B in 2022
Founded in 2016, Logixboard is a Seattle-based company that develops cloud platforms for freight forwarders. Its software increases transparency and communication with customers, helping logistics service providers enhance sales and customer retention.
Leyden Labs
Series B in 2022
Leyden Labs develops a Mucosal Protection Platform to protect against respiratory viruses, including influenza and coronaviruses. The company offers a portfolio of broad protective nasal sprays designed to reduce the risk of infection and limit transmission, aiming to improve public health through innovative protection methods. Its team combines biotechnology veterans with new talent to advance solutions that address common viral threats at the mucosal surface.
Papaya is a mobile application designed to streamline the bill payment process for users by allowing them to pay any bill quickly and easily using their mobile devices. By enabling users to snap a photo of their bills, Papaya eliminates the complexities of traditional payment methods such as mailing checks or navigating cumbersome online payment portals. The platform caters to billers across various industries, facilitating faster and more consistent payment collection. Papaya has gained recognition as one of the highest-rated financial technology applications, receiving over 70,000 reviews on the App Store. Additionally, the company is supported by prominent investors, reinforcing its position in the fintech sector.
Lighthouse
Series B in 2021
Lighthouse is a commercial platform tailored for the travel and hospitality industry, specializing in hotel management solutions. The company offers a cloud-based platform that visualizes and leverages data to enhance business success. By providing actionable market insights and business intelligence tools, Lighthouse enables hoteliers and hotel management companies to make informed revenue and distribution decisions. Its services include real-time data analytics, which empower users to maximize property occupancy rates and increase revenue and profit. Formerly known as OTA Insight, Lighthouse aims to transform complex market dynamics into manageable strategies that foster growth in the hospitality sector.
AppliedVR
Series B in 2021
AppliedVR is a Los Angeles‑based company that develops virtual reality therapeutic devices for pain and anxiety management in healthcare settings. Founded in 2013, it partners with institutions such as Cedars‑Sinai and Children’s Hospital Los Angeles to deliver its VR platform in hospitals, surgery centers, and exam rooms across the United States. The company’s flagship product, EaseVRx, is the first VR‑based prescription therapeutic to receive FDA Breakthrough Device Designation; it combines cognitive behavioral therapy and mindfulness to help patients alter pain perception and build coping skills. EaseVRx is self‑administered at home, enabling remote care and improving access, equity, and efficiency in chronic pain treatment. AppliedVR’s clinically validated, on‑demand platform supports both acute and chronic pain, promotes non‑drug pain management, and assists clinicians in achieving better long‑term patient outcomes.
Notable is an artificial intelligence platform for healthcare operations that automates administrative and operational tasks within health systems, clinics, and other care settings. The platform handles patient intake, scheduling, prior authorization, documentation, and billing automation, enabling providers and staff to streamline workflows and reduce manual workload for more efficient care delivery. It is deployed at over 10,000 sites of care and automates a million repetitive workflows daily across Registration and Intake, Scheduling and Referrals, Assistant, Authorizations, Care Gap Closure, and HCC Chart Review, leading to faster patient processing, improved care coordination, and stronger financial performance for healthcare organizations.
Stride Health
Series C in 2021
Stride Health, Inc. is a health benefits platform that specializes in providing affordable health coverage options for independent workers and part-time employees in the United States. The company offers a range of services, including dental plans, doctor and prescription insurance plans, and various health coverage options tailored to meet the needs of its customers. Stride Health simplifies the enrollment process by guiding users through selecting the most cost-effective health plans, aiming to optimize their tax benefits and enhance their take-home pay. Founded in 2013 and based in San Francisco, California, the company was previously known as Covered, Inc. and rebranded to Stride Health, Inc. in March 2013. Stride Health also provides personal advisory services to assist clients in navigating the complexities of their health insurance options.
Founded in 2014 by Fredrik Skantze and Per Made, Funnel is a software company specializing in marketing analytics. It integrates with over 400 data sources to automate data collection from various advertising platforms, catering to e-commerce companies, media agencies, brands, B2B businesses, mobile apps, and gaming companies.
Centivo
Venture Round in 2021
Centivo Corporation is a health insurance provider that specializes in offering innovative health plans for self-funded employers, employees, and clinicians. Established in 2016 and headquartered in Stamford, Connecticut, with additional offices in New York and Buffalo, Centivo serves as an alternative to traditional insurance carriers and third-party administrators. The company integrates technology, network management, claims processing, and customer support to effectively administer health benefits. Centivo emphasizes collaboration between employees and their primary care teams to coordinate healthcare needs, encouraging members to engage in high-value care through personalized matching tools and a user-friendly app. By focusing on controlling costs and improving navigation through the healthcare system, Centivo positions itself as a dedicated partner to employers, ensuring accountability and minimizing waste in healthcare spending.
NOCD Inc. is a Chicago-based company founded in 2014 that specializes in developing a mobile application aimed at assisting individuals with obsessive-compulsive disorder (OCD). The platform connects users to licensed therapists who specialize in OCD through face-to-face video therapy sessions. Utilizing cognitive behavioral therapy techniques, the application guides users in self-treatment and monitoring of their symptoms, offering tools for exposure and response prevention exercises. In addition to therapy sessions, NOCD provides 24/7 support via self-help resources and peer communities, facilitating ongoing care and enabling patients to manage their condition effectively. The company focuses on improving treatment outcomes for OCD through its innovative online platform.
GYENNO Technologies
Series B in 2021
GYENNO Technologies is a digital health company developing medical devices for people with disabilities. GYENNO's products include GYENNO spoon, which helps people with hand tremors eat without stress, and the GYENNO matrix, a wearable motion and gait quantitative evaluation system for Parkinson's disease.
Founded in 2013, Oviva specializes in digital behavior change programs for managing type 2 diabetes and obesity. Their platform combines smartphone apps and learning portals, supported by dietitian-led coaching, enabling patients to improve their health remotely and reducing healthcare system costs.
Carrot Fertility
Series C in 2021
Carrot Fertility, Inc. offers comprehensive fertility benefits services for employers, supporting employees throughout their fertility healthcare journey on a global scale. Founded in 2015 and headquartered in San Francisco, California, the company provides a range of services including egg freezing, in vitro fertilization, adoption, donor and gestational carrier services. It also features Carrot Rx, a premium pharmacy experience for fertility medications, and Carrot Pregnancy, which offers virtual access to experts and on-demand doctor-approved content. Additionally, Carrot Card is a flexible debit card that employees can use to pay for fertility care. Carrot Fertility aims to help companies customize their fertility benefits, ensuring that employees receive the necessary financial, medical, and emotional support as they pursue parenthood. The company has expanded its presence with additional offices in major cities including Chicago, New York, Dublin, Geneva, Tokyo, and Seoul.
Innovusion
Series B in 2021
Innovusion, founded in 2016 and based in Sunnyvale, California, specializes in developing autonomous driving perception systems. The company is renowned for its image-grade LiDAR sensor systems, which are designed to meet the rigorous demands of level 4 and 5 autonomous vehicles as well as Advanced Driver Assistance Systems (ADAS). Innovusion's products stand out due to their combination of long range, high resolution, hardware-accelerated sensor fusion, compact design, ease of integration, and cost-effectiveness.
MoEngage, Inc. is a technology company that provides a cloud-based user analytics and engagement platform aimed at enhancing customer retention and lifetime value for consumer businesses. Founded in 2014 and headquartered in San Francisco, California, the company serves various industries, including e-commerce, telecommunications, travel and hospitality, and banking and finance. MoEngage's platform enables businesses to deliver personalized interactions through multiple channels, such as push notifications, in-app messaging, web push, and SMS, all managed from a single dashboard. With a focus on machine learning, the platform optimizes customer engagement by analyzing user behavior and delivering tailored recommendations. MoEngage also has offices in several international locations, including Bengaluru, Singapore, London, Jakarta, Bangkok, Ho Chi Minh City, and Berlin.
SonderMind
Series C in 2021
SonderMind is a Denver-based digital health company established in 2017, specializing in accessible and approachable mental health services. It operates an online platform that connects individuals with a network of licensed therapists, offering a range of services including video telehealth and in-person sessions. SonderMind focuses on various mental health conditions such as anxiety, depression, ADHD, and PTSD, among others. The company aims to streamline the process of finding and accessing mental health care, ensuring a good match between clients and therapists, while also supporting therapists by handling administrative and billing tasks.
Embark offers dog DNA testing that ends preventable diseases in dogs. It was founded by top experts in genomics, computational biology, and software design to sell an industry-leading dog DNA test. They use a clinical-grade CLIA-certified SNP chip to provide the most accurate and comprehensive results (200,000+ genetic markers) available on the market.
Their data contributes to proprietary genetics research that will help dog owners optimize nutrition, exercise, allergies, and prevent a variety of heritable conditions. Their technological advantage, intellectual capital, and research-focus enable them to push canine health toward our shared vision of preventative veterinary care.
Castor is an international health-tech company that provides a cloud-based clinical data platform designed to streamline the clinical trial process for researchers globally. Founded by CEO Derk Arts, MD, Ph.D., the platform is utilized by over 50,000 researchers in 90 countries, supporting more than 4,000 studies across diverse therapeutic areas, including diabetes, cardiovascular disease, rare diseases, infectious diseases, and oncology. Castor's platform facilitates the collection and analysis of extensive data from both traditional and remote trials, having reached significant milestones such as 180 million data points and 2 million enrolled patients. The company's mission is to make research data reusable, thereby enabling AI-driven clinical trials and enhancing the overall impact of data within the medical research community.
Prime Medicine
Series B in 2021
Prime Medicine is a biotechnology company focused on developing genetic therapies using its innovative Prime Editing technology. This next-generation gene editing method allows for precise "search and replace" modifications in the genome, aimed at restoring normal genetic function. The company targets a wide range of diseases with significant unmet medical needs, leveraging the efficiency and versatility of its gene editing capabilities to address the underlying causes of these conditions. Through its commitment to advancing gene editing, Prime Medicine seeks to transform the landscape of genetic medicine.
Orient Speech Therapy
Series C in 2021
Orient Speech Therapy Center specializes in providing professional speech and language therapy services for children facing communication challenges, including those with autism or speech disorders. The center focuses on the early screening, clinical diagnosis, and therapeutic interventions essential for improving children's speech and social skills. It offers a range of refined curricula designed specifically for young learners, including the Star Curriculum, phonics and oral muscle courses, expression courses, and exercise classes. Through these structured programs, Orient Speech Therapy Center aims to enhance the communicative abilities of children, enabling them to express themselves more effectively and engage socially.
Pulmocide
Series C in 2021
Founded in London in 2007, Pulmocide specializes in developing inhaled medicines targeting serious viral and fungal respiratory infections. Its focus is on creating drugs optimized for lung delivery to maximize efficacy while minimizing systemic exposure.
Affinia Therapeutics
Series B in 2021
Affinia Therapeutics develops adeno-associated virus (AAV) gene therapies for muscular and central nervous system diseases. The company uses an AAV vector design platform built on synthetic and systems biology, high-throughput screening, and tissue- and single-cell-resolution analyses to create vectors with improved properties. It leverages sequencing, artificial intelligence, and structural modeling to enable rational design of therapies. Headquartered in Waltham, Massachusetts, Affinia Therapeutics was founded in 2019 and targets diseases with significant unmet needs in muscle and CNS.
CareStack
Series C in 2021
CareStack is a company that provides an all-in-one cloud-based platform designed to streamline dental practice management. The platform integrates various functionalities including patient engagement, scheduling, telehealth conferencing, charting, automated reminders, claims and billing, and business insights. This comprehensive solution aims to enhance operational efficiency, improve patient care, and increase financial success for dental practices. CareStack's mission is to support dentists in achieving better practice management and an improved quality of life through its technology-driven offerings.
Proximie is a health technology company that enables surgeons worldwide to collaborate remotely using augmented reality, artificial intelligence, and machine learning. Its platform allows surgeons to visually guide complex surgeries, democratizing access to advanced surgical knowledge.
Founded in 2014 by Stanford University Biodesign Fellows collaborating with leading urologists, Zenflow develops a novel spring device to alleviate permanent benign prostatic hyperplasia (BPH) symptoms in men. Its minimally invasive solution preserves natural anatomy and improves patient experience.
1upHealth
Series B in 2021
Founded in 2017, 1upHealth operates a health data aggregation platform that securely centralizes patient records from various electronic medical systems. Its platform enables patients to control and share their consolidated digital health record with providers, while also allowing developers to access clinical data from connected clinics and hospitals.
Firefly Health
Series B in 2021
Founded in 2016, Firefly Health delivers AI-driven virtual-first primary care. Its platform connects patients with healthcare professionals for convenient, continuous care, focusing on common conditions and women's health issues.
OZiva is a plant-based clean nutrition brand that specializes in producing organic nutritional products aimed at promoting healthier lifestyle choices. The company offers a diverse range of items, including those focused on fitness, hair and skin health, and both men's and women's wellness. OZiva distinguishes itself by integrating ancient Ayurvedic principles with modern micronutrient science, creating a comprehensive nutrition and fitness ecosystem. This approach not only addresses everyday nutritional needs but also fosters a supportive digital community for individuals pursuing healthier living. Through its offerings, OZiva aims to make healthy dietary planning convenient and accessible for its customers.
Innovusion
Series B in 2021
Innovusion, founded in 2016 and based in Sunnyvale, California, specializes in developing autonomous driving perception systems. The company is renowned for its image-grade LiDAR sensor systems, which are designed to meet the rigorous demands of level 4 and 5 autonomous vehicles as well as Advanced Driver Assistance Systems (ADAS). Innovusion's products stand out due to their combination of long range, high resolution, hardware-accelerated sensor fusion, compact design, ease of integration, and cost-effectiveness.
LakeShore Biopharma
Series B in 2021
Yisheng Biopharma Co., Ltd. is a biopharmaceutical company focused on the research, development, manufacturing, and marketing of immuno-oncology products and vaccines. Founded in 2002 and headquartered in Beijing, the company operates in China, the United States, Cambodia, and Singapore. Yisheng Biopharma utilizes its novel PIKA immunomodulating technology to enhance immune responses against cancers and infectious diseases. Key products under development include YS-ON-001, an investigational therapy aimed at treating advanced solid tumors, as well as YS-HBV-001, a vaccine for hepatitis B, and a PIKA-based rabies vaccine designed for rapid protection against rabies infection. The company's innovative approach targets multiple immune pathways to improve treatment outcomes.
Cohort, Inc. is a software company focused on enhancing chronic care management and clinical trial processes. Based in New York with an additional office in San Francisco, the company utilizes clinical artificial intelligence and natural language processing to analyze electronic health records. This analysis includes evaluating diagnostics, medications, and clinical notes to provide context relevant to specific patients and their conditions. Cohort’s software streamlines the identification and enrollment of eligible patients, generates tailored care plans, and automates compliance and billing tasks. The company’s solutions are designed to enable Primary Care Providers to improve the scale, efficiency, and outcomes of their Chronic Care Management programs while facilitating clinical trial identification and enrollment.
Metcela is a clinical-stage biotechnology company based in Kawasaki, Japan, developing fibroblast-based therapies for heart disease. Its approach uses VCAM-1–positive cardiac fibroblasts derived from a patient’s own heart to repair damaged tissue and reestablish a supportive microenvironment, rather than replacing cells. The lead program, MTC001, aims to restore heart function by promoting natural healing in preclinical studies. Metcela was founded in 2016.
Centivo Corporation is a health insurance provider that specializes in offering innovative health plans for self-funded employers, employees, and clinicians. Established in 2016 and headquartered in Stamford, Connecticut, with additional offices in New York and Buffalo, Centivo serves as an alternative to traditional insurance carriers and third-party administrators. The company integrates technology, network management, claims processing, and customer support to effectively administer health benefits. Centivo emphasizes collaboration between employees and their primary care teams to coordinate healthcare needs, encouraging members to engage in high-value care through personalized matching tools and a user-friendly app. By focusing on controlling costs and improving navigation through the healthcare system, Centivo positions itself as a dedicated partner to employers, ensuring accountability and minimizing waste in healthcare spending.
Odaseva is a company specializing in data management solutions for large enterprises utilizing Salesforce. It offers a comprehensive cloud-based platform that focuses on data protection, privacy, and governance. The Odaseva Enterprise Data Security Platform is designed to ensure the confidentiality, integrity, and availability of critical business information by providing integrated security products and services. Key features of the platform include backup and recovery, archiving, monitoring of governor limits, and compliance support for regulations such as GDPR. By enabling businesses to take full control of their data, Odaseva helps eliminate risks and facilitates confident digital transformation.
SnapDocs, Inc. is a real estate technology company that specializes in digital mortgage closings. Founded in 2013 and headquartered in San Francisco, California, SnapDocs provides a platform that connects lenders, title companies, notary signing agents, and homebuyers, facilitating a streamlined closing process. The platform automates interactions among these participants, ensuring efficiency, accuracy, and consumer satisfaction. It offers features such as performance metrics for mobile notary signing agents, customizable workflows for lenders and real estate professionals, and early access to closing packages for homebuyers. By leveraging advanced automation and patented technology, SnapDocs enhances the closing experience, enabling clients to save time and reduce costs while maintaining compliance. The company's focus on improving both borrower experience and business outcomes positions it as a leading solution in the mortgage closing industry.
Carrot Fertility
Series B in 2020
Carrot Fertility, Inc. offers comprehensive fertility benefits services for employers, supporting employees throughout their fertility healthcare journey on a global scale. Founded in 2015 and headquartered in San Francisco, California, the company provides a range of services including egg freezing, in vitro fertilization, adoption, donor and gestational carrier services. It also features Carrot Rx, a premium pharmacy experience for fertility medications, and Carrot Pregnancy, which offers virtual access to experts and on-demand doctor-approved content. Additionally, Carrot Card is a flexible debit card that employees can use to pay for fertility care. Carrot Fertility aims to help companies customize their fertility benefits, ensuring that employees receive the necessary financial, medical, and emotional support as they pursue parenthood. The company has expanded its presence with additional offices in major cities including Chicago, New York, Dublin, Geneva, Tokyo, and Seoul.
Checkmate Pharmaceuticals
Series C in 2020
Checkmate Pharmaceuticals is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, founded in 2015. The company specializes in developing novel immunotherapies for cancer treatment, with a focus on CpG oligonucleotides. These oligonucleotides activate an anti-tumor T-cell response and are combined with checkpoint inhibition to enhance the immune system's ability to combat tumors. Checkmate Pharmaceuticals has formed strategic alliances with Merck KGaA and Pfizer to advance its clinical programs, aiming to increase the efficacy of existing immunotherapies and provide new treatment options for cancer patients.
PatientPing
Series C in 2020
PatientPing, Inc. is a health technology company that has developed a national care coordination network aimed at enhancing communication among healthcare providers. Founded in 2013 and headquartered in Boston, Massachusetts, the company offers real-time notifications and care guidelines to various healthcare professionals, including physicians, nurses, case managers, and care coordinators. This network spans hospitals, emergency departments, accountable care organizations, physician practices, skilled nursing facilities, home health agencies, and payers. PatientPing's platform includes a tool called Spotlights, which leverages real-time data to analyze utilization and performance trends in patient care. By improving information sharing among care teams, PatientPing facilitates higher quality, cost-effective care, ultimately aiming to enhance patient outcomes and experiences. The company also maintains a strategic partnership with MedAllies, Inc. and operates as a subsidiary of SVB Leerink Holdings LLC.
NodThera is a UK-based biotechnology company focused on developing novel inhibitors of the NLRP3 inflammasome for treating inflammatory and neuroinflammatory diseases. Established in 2016, it operates laboratories in Little Chesterford (UK) and Seattle (US), with corporate offices in Lexington (US). The company's primary research involves inflammasomes, multi-protein complexes targeting conditions such as arthritis, atherosclerosis, Alzheimer's disease, diabetes, and certain cancers.
Avalyn Pharma
Series B in 2020
Avalyn Pharma is a biopharmaceutical company focused on developing therapies for severe respiratory diseases, notably idiopathic pulmonary fibrosis (IPF). Established in 2011, the company is headquartered in Seattle, Washington.
Rallybio is a clinical-stage biopharmaceutical company focused on developing therapies for severe and rare diseases. Its programs cover hematology, immuno-inflammation, maternal-fetal health and metabolic disorders, with a lead candidate aimed at preventing fetal and neonatal alloimmune thrombocytopenia, a life-threatening condition that can cause bleeding in fetuses and newborns. Founded in 2018 and based in New Haven, Connecticut, Rallybio develops therapies across antibodies, small molecules and engineered proteins to address unmet needs in rare diseases. Guided by experienced biopharma leadership, the company emphasizes translating biology into transformative therapies for underserved patients.
SonderMind
Series B in 2020
SonderMind is a Denver-based digital health company established in 2017, specializing in accessible and approachable mental health services. It operates an online platform that connects individuals with a network of licensed therapists, offering a range of services including video telehealth and in-person sessions. SonderMind focuses on various mental health conditions such as anxiety, depression, ADHD, and PTSD, among others. The company aims to streamline the process of finding and accessing mental health care, ensuring a good match between clients and therapists, while also supporting therapists by handling administrative and billing tasks.
Devoted Health
Series C in 2020
Founded in 2017, Devoted Health is dedicated to enhancing the health and well-being of older Americans by offering integrated Medicare Advantage plans. They provide personalized care through a combination of local providers, virtual and in-home care, dedicated guides, and advanced technology.
Xilio Therapeutics
Series B in 2020
Xilio Therapeutics is a clinical-stage biotechnology company focused on developing innovative immunotherapies to enhance the immune system's ability to combat cancer. The company specializes in tumor-selective immunotherapies, utilizing its proprietary technology to maximize the effectiveness of immuno-oncology treatments while minimizing side effects outside the tumor. Among its key products is XTX201, which aims to induce immune activity directly within tumors, demonstrating improved antitumor effects. Founded in 2015 and based in Waltham, Massachusetts, Xilio Therapeutics was previously known as Akrevia Therapeutics until its rebranding in March 2020. The company is dedicated to advancing a pipeline of novel immuno-oncology molecules, including tumor-activated cytokines and antibodies, with the goal of significantly improving patient outcomes in cancer treatment.
Whatfix provides a digital adoption platform that enhances user productivity, ensures process compliance, and improves user experience across various applications. It offers simulated application environments for training and no-code application analytics.
MoEngage, Inc. is a technology company that provides a cloud-based user analytics and engagement platform aimed at enhancing customer retention and lifetime value for consumer businesses. Founded in 2014 and headquartered in San Francisco, California, the company serves various industries, including e-commerce, telecommunications, travel and hospitality, and banking and finance. MoEngage's platform enables businesses to deliver personalized interactions through multiple channels, such as push notifications, in-app messaging, web push, and SMS, all managed from a single dashboard. With a focus on machine learning, the platform optimizes customer engagement by analyzing user behavior and delivering tailored recommendations. MoEngage also has offices in several international locations, including Bengaluru, Singapore, London, Jakarta, Bangkok, Ho Chi Minh City, and Berlin.
WelbeHealth
Series C in 2020
WelbeHealth serves frail seniors through its PACE (Program of All-Inclusive Care for the Elderly) model, providing comprehensive medical and social care. This enables participants to live better, longer, and more independently. The company coordinates various aspects of care, including medical appointments, therapy sessions, transportation, meals, and personal care services.
BenchSci is a developer of a research intelligence platform that leverages artificial intelligence and machine learning to enhance the efficiency of biomedical research. The company's technology translates both closed and open-access data into actionable recommendations for specific experiments, particularly in antibody extraction. By streamlining the experimental process, BenchSci allows researchers and scientists to conduct successful experiments more quickly and with reduced resource wastage. The platform is utilized by pharmaceutical companies and over 4,300 research centers globally, significantly contributing to the acceleration of drug discovery and biomedical advancements.
Founded in 2014 by Fredrik Skantze and Per Made, Funnel is a software company specializing in marketing analytics. It integrates with over 400 data sources to automate data collection from various advertising platforms, catering to e-commerce companies, media agencies, brands, B2B businesses, mobile apps, and gaming companies.
Founded in 2013, Oviva specializes in digital behavior change programs for managing type 2 diabetes and obesity. Their platform combines smartphone apps and learning portals, supported by dietitian-led coaching, enabling patients to improve their health remotely and reducing healthcare system costs.
Wellframe
Series C in 2019
Wellframe Inc. is a Boston-based company that specializes in digital care management and health advocacy solutions. Founded in 2011, it partners with health plans across the country to enhance the relationship between healthcare providers and members. Wellframe's offerings include a mobile application that facilitates daily health reporting, a care team dashboard to prioritize patient needs, and an array of communication tools for two-way messaging. The company also provides comprehensive operational services, such as implementation support, recruiting, and analytics. Additionally, Wellframe's platform employs real-time data and artificial intelligence to deliver personalized care protocols, enabling caregivers to monitor patient status effectively and identify when intervention is necessary. By focusing on mobile patient engagement and care management, Wellframe aims to improve health outcomes and empower individuals in managing their health.
SnapDocs, Inc. is a real estate technology company that specializes in digital mortgage closings. Founded in 2013 and headquartered in San Francisco, California, SnapDocs provides a platform that connects lenders, title companies, notary signing agents, and homebuyers, facilitating a streamlined closing process. The platform automates interactions among these participants, ensuring efficiency, accuracy, and consumer satisfaction. It offers features such as performance metrics for mobile notary signing agents, customizable workflows for lenders and real estate professionals, and early access to closing packages for homebuyers. By leveraging advanced automation and patented technology, SnapDocs enhances the closing experience, enabling clients to save time and reduce costs while maintaining compliance. The company's focus on improving both borrower experience and business outcomes positions it as a leading solution in the mortgage closing industry.
CareStack
Series B in 2019
CareStack is a company that provides an all-in-one cloud-based platform designed to streamline dental practice management. The platform integrates various functionalities including patient engagement, scheduling, telehealth conferencing, charting, automated reminders, claims and billing, and business insights. This comprehensive solution aims to enhance operational efficiency, improve patient care, and increase financial success for dental practices. CareStack's mission is to support dentists in achieving better practice management and an improved quality of life through its technology-driven offerings.
Recurly, Inc. is a provider of enterprise-class subscription management and billing solutions aimed at optimizing revenue growth for businesses across various industries, including digital media, streaming, publishing, SaaS, consumer goods, and professional services. Founded in 2009 and headquartered in San Francisco, California, with additional offices in Boulder, Colorado, and New Orleans, Louisiana, Recurly simplifies the complexities of subscription billing and revenue optimization. Its platform facilitates recurring billing automation, offering features such as customizable hosted billing pages, account management services, and actionable insights to enhance decision-making. By reducing subscriber churn and improving operational efficiency, Recurly enables businesses to quickly integrate payment solutions and focus on growth. The company is also a Level 1 PCI compliant service provider, which minimizes costs associated with PCI compliance for its clients.
Insilico Medicine
Series B in 2019
Insilico Medicine, Inc. is a biotechnology company that leverages artificial intelligence (AI) to transform drug discovery, biomarker development, and aging research. Founded in 2014 and based in Baltimore, Maryland, the company has established itself as a pioneer in applying advanced AI techniques, such as generative adversarial networks and reinforcement learning, to create novel molecular structures for various diseases, including cancer and age-related conditions. Insilico Medicine operates an integrated platform that covers all stages of drug discovery, from initial research to clinical trial analysis. Its projects include Pharma.AI, which offers machine learning services to various sectors, and Young.AI, a platform focused on aging predictors. The company also pursues internal drug discovery initiatives targeting diseases like Alzheimer's and Parkinson's, and has partnered with Life Extension to produce nutraceutical products utilizing deep learning and bioinformatics. Additionally, Insilico Medicine provides consumer applications aimed at enhancing health and longevity.
Protenus, Inc. is a healthcare compliance analytics company based in Baltimore, Maryland, which was founded in 2014. The company specializes in an AI-driven platform designed to audit access to patient records across health systems in the United States. Protenus' technology identifies risks such as inappropriate access to patient data and the misuse of controlled substances by healthcare staff. By automating the detection of policy violations and other anomalous behaviors, the platform supports healthcare organizations in protecting patient privacy and reducing operational risks. Protenus is recognized for its innovation and commitment to fostering safe patient outcomes while enhancing the reputation of healthcare providers. The company has received accolades such as being named one of America's Best Startup Employers by Forbes and recognized as a Great Place to Work.
Simon Data
Series C in 2019
Simon Data develops a customer data platform designed to enhance campaign performance via precise segmentation and personalization. Its platform identifies purchase intent, predicts churn, estimates customer lifetime value, and enables brands to deliver personalized experiences across channels.
Buoy Health
Series B in 2019
Buoy Health is a health technology company that develops AI-powered digital health tools to help individuals manage healthcare options. It offers an online healthcare assistant that analyzes symptoms, performs first-line triage, and provides treatment recommendations. Its platform delivers real-time symptom analysis and helps users navigate the healthcare system, research benefits, and locate in-network providers. For employers, the platform surfaces benefits information, guides employees to in-network providers, and integrates with other health portals. Founded in 2014 and based in Boston, Buoy Health aims to resemble a physician-patient conversation through machine learning and proprietary data, enabling users to make informed care decisions.
Optimus Ride
Series B in 2019
Optimus Ride is a self-driving vehicle company located in Boston, Massachusetts, focused on developing technologies that promote efficient, sustainable, and equitable mobility systems. As a spinoff from the Massachusetts Institute of Technology, the company leverages over 30 years of interdisciplinary research in self-driving technologies, electric vehicles, and Mobility-on-Demand Systems. Optimus Ride specializes in creating self-driving technology systems tailored for geofenced environments, utilizing innovations in complex sensor fusion, mapping, computer vision, and machine learning. The company's expertise is further enhanced by a team with extensive industrial and entrepreneurial experience in manufacturing robots, urban design, and shared vehicle fleet management, allowing it to offer versatile transportation solutions that range from commercial vessel operations to transit options.