1upHealth, Inc. is a health-tech company based in Boston, Massachusetts, founded in 2017. It operates a health data aggregation and centralization platform that facilitates the secure transmission of medical data between health systems and consumer applications. The platform consolidates health information from various electronic medical record systems, allowing users to control and share their digital health records with healthcare providers. Additionally, it enables providers to access and query the most current patient data from multiple connected health systems. The platform also supports software developers by providing access to clinical data from various clinics and hospitals, ultimately aiming to improve healthcare outcomes and reduce costs through better data utilization.
Proximie Inc., based in Bedford, Massachusetts, offers a secure software platform that facilitates virtual surgical collaboration among surgeons. By leveraging advanced telecommunication, augmented reality, artificial intelligence, and machine learning technologies, Proximie's platform enables real-time, peer-to-peer assistance during surgeries, regardless of location. This innovative approach allows surgeons to share expertise before, during, and after procedures, effectively overcoming the barriers of time and distance. Furthermore, the platform is compatible with various devices and software used in operating rooms, allowing for seamless integration and interaction. Proximie's mission is to enhance surgical knowledge and skills, enabling surgeons to refine their techniques in diverse settings, even with limited bandwidth.
RightHand Robotics, Inc. specializes in manufacturing robotic order-picking systems designed for various industrial applications, including e-commerce, food handling, and flexible manufacturing. The company offers innovative products such as the ReFlex SF, which features a 3D-printed palm equipped with servos and compliant fingers, and the ReFlex TakkTile, a tactile sensor that enhances the robots' ability to grasp items gently and make adjustments to avoid errors. Their technology allows robots to automatically grasp a wide range of items from bins and cases, eliminating the need for extensive data-entry or parameter-tuning, thereby making the systems cost-effective and adaptable to the evolving needs of businesses. Founded in 2015, RightHand Robotics is headquartered in Cambridge, Massachusetts, with a sales and business development office located in Frankfurt, Germany.
Stride Health, Inc. operates a health benefits platform tailored for independent workers and part-time employees in the United States. The platform enables users to select and enroll in various affordable health coverage options, including dental, vision, and prescription insurance plans. Stride Health simplifies the process of finding suitable health insurance by providing personalized recommendations and tax deduction support, thereby helping customers maximize their take-home pay. The company, originally known as Covered, Inc., rebranded to Stride Health in March 2013 and has since been based in San Francisco, California. Through its services, Stride Health aims to make healthcare accessible and manageable for its users.
Funnel Operation AB, founded in 2014 and headquartered in Stockholm, Sweden, specializes in marketing analytics and reporting software designed to automate data collection for marketers. The company's platform integrates with over 400 marketing and advertising sources, allowing users to streamline data feeding into various tools such as Business Intelligence systems, Data Warehouses, Google Sheets, Google Data Studio, and Google Analytics. Funnel's offerings include dashboards and reports for simplified marketing analysis, a data studio connector for aggregating marketing data, and APIs that facilitate data collection and distribution. The company serves a diverse clientele, including e-commerce businesses, media agencies, brands, B2B companies, mobile applications, and gaming firms, helping them manage advertising performance data effectively and gain insights for informed decision-making.
Oviva is a digital health company providing medically-oriented nutritional counseling services in Switzerland, Germany, and the United Kingdom. Founded in 2013 and headquartered in Ingenbohl, Switzerland, Oviva offers personalized behavior change programs aimed at managing diet and lifestyle-related health issues like obesity and diabetes. Their services are delivered through a network of qualified dietitians who work with clients both in clinics and remotely. The company has developed a smartphone application that allows users to engage with their dietitian, maintain a food diary, set health goals, and access tailored educational materials. This technology-enabled approach helps patients achieve better health outcomes while reducing the need for in-person appointments, ultimately lowering healthcare costs by preventing complications associated with these conditions.
Carrot Fertility, Inc. provides comprehensive fertility benefits services to employers, supporting employees throughout their fertility healthcare journey globally. Founded in 2015 and headquartered in San Francisco, the company offers a range of services, including egg freezing, in vitro fertilization, adoption, donor, and gestational carrier services. Additionally, it features Carrot Rx, which facilitates a premium pharmacy experience for fertility medications, and Carrot Pregnancy, providing virtual access to experts and on-demand content. Carrot Card is a flexible benefits debit card that allows employees to pay for their care. By partnering with modern companies, Carrot Fertility enables organizations to customize fertility benefits that deliver financial, medical, and emotional support to employees seeking to become parents. The company also has offices in major cities around the world, including Chicago, New York, Dublin, Geneva, Tokyo, and Seoul.
MoEngage, Inc. is a customer engagement and analytics platform that focuses on enhancing customer retention and lifetime value for businesses. Founded in 2014 and headquartered in San Francisco, California, MoEngage offers cloud-based marketing services that enable companies to execute campaigns across multiple channels, including in-app messaging, web, and SMS. Its platform utilizes machine learning to optimize customer interactions, providing tools for user intelligence, push notifications, in-app recommendations, and email communications, all accessible through a single dashboard. The company serves various industries, including e-commerce, telecommunications, travel and hospitality, and banking and finance. MoEngage also has a strategic partnership with Vidora, Inc., and maintains additional offices in several international locations, including Bengaluru, Singapore, London, Jakarta, Bangkok, Ho Chi Minh City, and Berlin.
SonderMind LLC, founded in 2017 and based in Denver, Colorado, operates a digital platform that connects individuals with mental health professionals for both telehealth and in-person sessions. The company offers a comprehensive directory of therapists who provide services for a range of mental health issues, including anxiety, depression, PTSD, and more. SonderMind's platform aims to make behavioral health services more accessible and user-friendly, allowing consumers to easily find and schedule appointments with well-matched therapists. By streamlining the connection between clients and providers, SonderMind enhances the therapeutic experience while allowing therapists to concentrate on patient care without being burdened by administrative tasks.
Provider of speech and language therapy services intended for stunted children with speech disorder. The company provides early screening, clinical diagnosis, and therapeutic interventions to children with autism or speech disorder, enabling children to speak and communicate better.
Pulmocide Ltd is a London-based company established in 2007 that specializes in developing inhaled medicines aimed at treating serious viral and fungal infections of the respiratory tract. The company focuses on creating a new generation of antifungal drugs tailored for inhalation, which enhances the delivery of medication directly to the lungs while reducing systemic exposure. This targeted approach is designed to improve efficacy against respiratory aspergillosis and minimize systemic toxicities, thereby offering safe and effective treatment options for patients with acute and chronic respiratory diseases.
CareStack is a cloud-based platform designed to meet the comprehensive administrative and clinical needs of dental practices. It integrates various functionalities, including practice management, patient engagement, scheduling, telehealth conferencing, charting, automated reminders, claims processing, and business analytics, all within a single interface. This all-in-one solution is particularly beneficial for large and growing dental practices, helping them enhance productivity, reduce operational costs, and improve patient care. By centralizing and automating key processes, CareStack aims to elevate the financial success of dental offices while ensuring a streamlined experience for both patients and staff.
Snapdocs, Inc. is a real estate technology company that provides a digital platform designed to streamline the mortgage closing process. Founded in 2012 and based in San Francisco, California, Snapdocs connects lenders, title and escrow companies, notary publics, and home buyers to enhance collaboration and efficiency in real estate transactions. The platform features advanced automation and standardized workflows, allowing participants to choose their preferred closing methods while improving accuracy and consumer satisfaction. It also enables notary signing agents to showcase their qualifications, helping them attract potential clients. By simplifying mortgage loan closings and improving the overall borrower experience, Snapdocs empowers its users to operate more effectively and transparently in a competitive market.
Checkmate Pharmaceuticals is a clinical-stage biotechnology company based in Cambridge, Massachusetts, that specializes in developing novel immunotherapies for cancer treatment. Founded in 2015, the company focuses on leveraging CpG oligonucleotides to enhance anti-tumor T-cell responses and overcome the mechanisms that allow tumors to evade immune detection. By combining its proprietary technology with checkpoint inhibition, Checkmate aims to improve the efficacy of existing immunotherapies and provide new treatment options for patients. The company has formed strategic alliances with major pharmaceutical firms, including Merck KGaA and Pfizer, to further its research and development efforts in the field of cancer immunotherapy.
PatientPing, Inc. operates a national care coordination network designed to connect healthcare providers through real-time notifications when patients receive care. Founded in 2013 and headquartered in Boston, Massachusetts, the company offers technology solutions for various healthcare stakeholders, including Accountable Care Organizations, hospitals, payers, and post-acute care facilities. Its network comprises a range of healthcare professionals, such as emergency case managers, primary care physicians, and care coordinators, facilitating improved collaboration and information sharing. PatientPing also features a tool called Spotlights, which analyzes real-time data to identify trends in healthcare utilization and performance. The company has formed a strategic partnership with MedAllies, Inc. and operates as a subsidiary of SVB Leerink Holdings LLC, focusing on enhancing patient outcomes and experiences through coordinated care.
Devoted Health is a new healthcare company serving seniors. Aiming to launch Medicare Advantage plans in 2019, their mission is to build a healthcare solution good enough for Mom. They will be devoted to the health and wellness of their members by helping them navigate the health care system with personal guides, by utilizing world-class technology to enable a simplified experience, and by partnering with top providers for better health outcomes.
Devoted Health is a new healthcare company serving seniors. Aiming to launch Medicare Advantage plans in 2019, their mission is to build a healthcare solution good enough for Mom. They will be devoted to the health and wellness of their members by helping them navigate the health care system with personal guides, by utilizing world-class technology to enable a simplified experience, and by partnering with top providers for better health outcomes.
Whatfix is a digital adoption platform that assists enterprises in enhancing their training and support initiatives by delivering contextual information in a user-friendly manner. The platform employs real-time interactive guidance technology to provide personalized, in-app user assistance, transforming traditional training and support methods. By offering just-in-time guidance, Whatfix enables users to complete tasks more efficiently across various applications, including web, desktop, and mobile. This approach fosters a unified digital workflow and self-help experience, leading to increased user adoption and productivity. Clients benefit from improved process compliance, reduced time for completing critical operations, and access to data-driven insights that support informed decision-making.
MoEngage, Inc. is a customer engagement and analytics platform that focuses on enhancing customer retention and lifetime value for businesses. Founded in 2014 and headquartered in San Francisco, California, MoEngage offers cloud-based marketing services that enable companies to execute campaigns across multiple channels, including in-app messaging, web, and SMS. Its platform utilizes machine learning to optimize customer interactions, providing tools for user intelligence, push notifications, in-app recommendations, and email communications, all accessible through a single dashboard. The company serves various industries, including e-commerce, telecommunications, travel and hospitality, and banking and finance. MoEngage also has a strategic partnership with Vidora, Inc., and maintains additional offices in several international locations, including Bengaluru, Singapore, London, Jakarta, Bangkok, Ho Chi Minh City, and Berlin.
WelbeHealth is a healthcare organization dedicated to enhancing the quality of life for frail seniors through the PACE (Program of All-Inclusive Care for the Elderly) model. Founded by experienced physician entrepreneurs, the company provides comprehensive medical and social care, ensuring that participants receive coordinated support that includes medical and dental care, therapy services, transportation, and meal provisions. By focusing on the diverse needs of the elderly population, WelbeHealth aims to help them live longer, healthier, and more independent lives. The leadership team comprises professionals from prominent payer and provider organizations, reflecting a commitment to innovative and compassionate care. Through its holistic approach, WelbeHealth strives to unlock the potential of vulnerable seniors in the community, fostering an environment of empathy and support.
Wellframe Inc. is a digital health management company based in Boston, Massachusetts, that specializes in care management solutions and digital concierge services. Founded in 2011, Wellframe develops mobile patient engagement software that enhances care management by connecting patients with their care teams through a user-friendly mobile application. The platform utilizes real-time member-generated data and artificial intelligence to create personalized care protocols and facilitate two-way communication, allowing for timely interventions and better patient monitoring. Wellframe's offerings include health plan solutions, such as daily health reporting, care team dashboards, and omni-channel communication tools, as well as operational services like system integration and analytics. Additionally, the company provides strategic consulting and change management services to help healthcare organizations improve their care delivery and patient engagement processes.
Recurly, Inc. specializes in providing subscription management and billing solutions designed to optimize revenue growth for businesses across various industries, including digital media, streaming, publishing, SaaS, and consumer goods. Founded in 2009 and headquartered in San Francisco, California, with additional offices in Boulder and New Orleans, the company offers a comprehensive platform that automates recurring billing processes, enhances payment acceptance, and reduces subscriber churn through effective card recycling strategies. Recurly's services allow businesses to quickly implement subscription billing systems, manage customer-related billing issues effortlessly, and gain actionable insights into their operations. As a level 1 PCI compliant service provider, Recurly also helps clients minimize costs and obligations associated with payment security. By streamlining these functions, Recurly enables businesses to focus on growth and improve their overall subscriber economics.
Protenus, Inc. is a Baltimore-based company that specializes in a healthcare compliance analytics platform designed to protect patient privacy and secure health data. Utilizing artificial intelligence, the platform audits every access to patient records across leading health systems in the United States. It enables healthcare organizations to gain comprehensive insights into the usage of health data, proactively identifying risks such as inappropriate access to patient information and potential theft or misuse of controlled substances by staff. By alerting compliance teams to policy violations and other anomalous behaviors, Protenus empowers hospitals to make informed decisions to enhance data protection and safeguard their institutions. The company, which was established in 2014 and previously known as Protenus, LLC, focuses on reducing risk and optimizing operational efficiency for its partner hospitals.
Simon Data is the enterprise Customer Data Platform (CDP) that empowers brands to deliver data-driven, personalized customer experiences anywhere.The platform leverages enterprise-scale big data and machine learning to power customer communications in any channel. Simon’s unique approach allows brands to develop and deliver incredible personalization capabilities without needing to build and maintain massive bespoke data infrastructure. At Simon, our goal is to improve and optimize customer experiences by making the entire process, experimentation through analysis, a data-driven one.
Artemis Health Inc. is a health data analytics company that specializes in providing self-insured employers with actionable insights into their employee benefit programs. Founded in 2013 and headquartered in Salt Lake City, Utah, the company offers a platform that helps employers identify issues within their benefits programs, pinpoint opportunities for improvement, and track the effectiveness of implemented solutions. By leveraging their own benefits data, employers can make informed decisions aimed at reducing healthcare expenditures while enhancing the quality of health and wellness coverage for their employees. Artemis Health's approach aims to address inefficiencies in the U.S. healthcare system, ultimately supporting organizations in optimizing their benefit offerings.
Checkmate Pharmaceuticals is a clinical-stage biotechnology company based in Cambridge, Massachusetts, that specializes in developing novel immunotherapies for cancer treatment. Founded in 2015, the company focuses on leveraging CpG oligonucleotides to enhance anti-tumor T-cell responses and overcome the mechanisms that allow tumors to evade immune detection. By combining its proprietary technology with checkpoint inhibition, Checkmate aims to improve the efficacy of existing immunotherapies and provide new treatment options for patients. The company has formed strategic alliances with major pharmaceutical firms, including Merck KGaA and Pfizer, to further its research and development efforts in the field of cancer immunotherapy.
PharmEasy is a leading pharmacy aggregator in India that operates an online drug delivery platform aimed at enhancing the supply chain of pharmaceuticals. By digitizing the process, it connects patients with local pharmacy stores and diagnostic centers, ensuring they can easily access a wide range of medicines and healthcare products. The platform is designed to make healthcare services more accessible and affordable, emphasizing the importance of good health for everyone. Through its services, PharmEasy strives to simplify the healthcare experience for patients, allowing them to fulfill their medical needs efficiently.
Quartet Health, Inc. is a healthcare technology company that operates a cloud-based platform designed to enhance communication and collaboration between medical and behavioral health providers. Founded in 2014 and based in New York, the company partners with health plans and health systems to deliver actionable insights and reports on behavioral health conditions, ultimately aiming to improve patient outcomes. Quartet's platform facilitates access to suitable mental health care tailored to individual preferences and clinical needs, ensuring that care is compatible with patients' insurance plans. By connecting physicians, mental health providers, and insurance companies, Quartet seeks to improve the overall health of patients while also reducing healthcare costs.
Threat Stack specializes in providing security solutions tailored for cloud infrastructure, enabling DevOps and SecOps teams to innovate and scale securely. The Threat Stack Cloud Security Platform and Cloud SecOps Program are designed to address complex cloud security needs by delivering continuous security monitoring and risk assessment. This approach helps organizations identify and verify insider threats, external attacks, and compliance gaps in real-time. By focusing on cloud, hybrid-cloud, and containerized environments, Threat Stack empowers security and operations teams to effectively manage risk and compliance across their entire infrastructure.
VYNE Therapeutics is a late-stage biopharmaceutical company that specializes in the development and commercialization of serlopitant, a treatment for pruritus associated with various dermatologic conditions, including atopic dermatitis, psoriasis, and prurigo nodularis. The company aims to address a significant unmet medical need, as there are currently no approved therapies in the United States that specifically target pruritus in these conditions. In addition to its focus on dermatologic applications, VYNE is also investigating serlopitant for refractory chronic cough, a persistent cough that lasts more than eight weeks despite treatment. Serlopitant acts as a selective small molecule inhibitor of the neurokinin 1 receptor and is administered as an oral tablet once daily. The company has completed Phase II clinical trials for pruritus related to various conditions and is planning to advance into Phase III trials for prurigo nodularis, anticipating further data to support its clinical development. VYNE Therapeutics is headquartered in Redwood City, California, and was established in 2011.
Promentis Pharmaceuticals, Inc. is a biopharmaceutical company based in Milwaukee, Wisconsin, established in 2006. The company specializes in developing therapies for neuropsychiatric disorders, with a focus on addressing glutamatergic imbalance and oxidative stress. Promentis is known for its lead compound, SXC-2023, which targets System xc- to treat multiple conditions, including impulse control disorders and obsessive-compulsive disorder. In addition to SXC-2023, Promentis is also working on other compounds aimed at restoring glutamatergic neurotransmission, which is crucial for improving cortical function and managing various psychiatric disorders, including schizophrenia.
Snapsheet is a leader in virtual appraisals and cloud-native claims management software, focusing on transforming the end-to-end claims process through digitization and intelligent automation. The company's software facilitates various stages of claims management, including electronic intake of first notice of loss (FNOL), data investigation, technology-assisted investigation, claims assessment, and digital payment processing for settlements. By offering unmatched technology and processes, Snapsheet enhances customer experience and promotes organizational agility. It has established itself as an industry innovator, deploying one of the fastest digital auto insurance claims processes in the United States. Serving over 100 clients, including major insurance carriers and insurtech firms, Snapsheet is recognized as a trusted partner in claims innovation.
TraceLink, Inc. specializes in providing track and trace network solutions that enhance the life sciences supply chain and combat counterfeit prescription drugs. The company offers a range of products, including pharmaceutical serialization, drug tracking, and compliance solutions through its TraceLink Life Sciences Cloud. Key offerings include the Smart Rx Manager, which helps healthcare providers comply with the European Union Falsified Medicines Directive, and Serialized Product Intelligence, a cloud application that utilizes serialization data to identify supply chain issues and optimize operations. TraceLink serves a diverse clientele, including pharmaceutical companies, wholesale distributors, and re-packagers, and has established strategic partnerships with notable firms such as Amazon and KPMG. Founded in 2009 and headquartered in North Reading, Massachusetts, TraceLink also has offices in the United Kingdom, India, Singapore, and Brazil. The company's platform is recognized for its ability to deliver global connectivity and visibility across the pharmaceutical supply chain, ensuring compliance and improving operational efficiency.
Hua Medicine is a clinical-stage, innovative drug development company in China, focused on novel therapies for the treatment of diabetes and CNS disorders. Founded by pharma industry veterans and funded by a premier group of international VC investment firms such as Fidelity Asia, Fidelity Biosciences, ARCH Ventures, Venrock, SAIL and WuXi Ventures, the company has in-licensed from major pharma, world-wide rights to a potential best-in-class, oral drug for the treatment of Type 2 Diabetes which utilizes a novel mechanism of action.
Kyruus, Inc. is a provider of web-based software solutions focused on optimizing physician networks for hospitals, health systems, and life science companies. Founded in 2010 and headquartered in Boston, Massachusetts, Kyruus offers a suite of analytically driven products designed to enhance the engagement, management, and performance of healthcare providers. Its solutions include Kyruus Passport, which allows physicians to track their activity and productivity, and Kyruus Profiles, which provides administrators with tools to monitor and analyze physician performance. Additionally, the company offers Kyruus MDSeekyr for identifying high-value providers and Kyruus Insight Reports for evaluating physician network trends and performance. The ProviderMatch suite further aids hospitals in connecting patients with the most suitable providers, ensuring a seamless patient experience while aligning provider availability with patient demand. Through its proprietary data management platform, Kyruus leverages accurate data to facilitate effective appointments and enhance overall patient care.
Aclaris Therapeutics is a clinical-stage biopharmaceutical company based in the United States, specializing in the development of innovative dermatologic and immunologic therapies. Founded by the team behind Vicept Therapeutics, Aclaris is dedicated to addressing significant unmet medical needs in dermatology and immunology, particularly in areas lacking FDA-approved treatments. The company operates in two main segments: therapeutics and contract research. The therapeutics segment focuses on creating novel drug candidates for immuno-inflammatory diseases, while the contract research segment generates revenue by providing laboratory services. Aclaris's pipeline includes drug candidates such as Zunsemetinib, an oral MK2 inhibitor, aiming to fill critical treatment gaps in the healthcare landscape.
Iora Health, Inc. is a healthcare provider based in Boston, Massachusetts, specializing in primary care services across the United States. Founded in 2010, the company is committed to overcoming the barriers typically present in the healthcare system by offering personalized care for each patient. Each individual is assigned a dedicated personal physician and health coach, who maintain regular communication through various channels, including email, text, and video, in addition to in-person consultations. Iora Health employs a team-based approach that includes a doctor or nurse practitioner, nurse, behavioral health specialist, and health coach, all supported by a proprietary technology platform for effective population health management. The organization also provides educational programs, such as group visits, to assist patients in achieving their health goals and managing their overall well-being.
Innovent Biologics, Inc. is a prominent biopharmaceutical company based in Suzhou, China, specializing in the discovery, development, manufacture, and commercialization of monoclonal antibody drug candidates. The company focuses on various therapeutic areas, including oncology, ophthalmology, immunology, and metabolic diseases. Its flagship product, Tyvyt (sintilimab), is an anti-PD-1 monoclonal antibody used in treating multiple cancers and is featured on the National Reimbursement Drug List. Innovent has developed several other promising candidates, including biosimilars and bispecific antibodies for conditions such as non-Hodgkin’s lymphoma, autoimmune diseases, and advanced solid tumors. The company has established strategic collaborations with major global pharmaceutical firms, enhancing its research and development capabilities. Founded in 2011, Innovent has a strong management team with extensive experience in biologics, and it continues to expand its portfolio of therapeutic options while maintaining a commitment to innovation in the biopharmaceutical industry.
REGENXBIO Inc. is a clinical-stage biotechnology company focused on developing gene therapy product candidates that utilize its proprietary NAV Technology Platform, which is based on adeno-associated virus (AAV) gene delivery. This platform aims to address genetic defects and enable cells to produce therapeutic proteins or antibodies to combat various diseases. The company's lead candidate, RGX-314, is currently undergoing Phase I/IIa clinical trials for wet age-related macular degeneration. Other notable product candidates include RGX-121 for mucopolysaccharidosis type II, RGX-111 for mucopolysaccharidosis type I, RGX-181 for late infantile neuronal ceroid lipofuscinosis type II, and RGX-501 for homozygous familial hypercholesterolemia, all in various stages of clinical trials. Additionally, REGENXBIO licenses its NAV Technology Platform to other biotechnology and pharmaceutical companies and has partnered with Neurimmune AG to develop vectorized antibodies for neurodegenerative diseases. Founded in 2008 and headquartered in Rockville, Maryland, the company was previously known as ReGenX Biosciences, LLC before rebranding in 2014.
Flywire operates an online payment platform that facilitates both domestic and international transactions, catering primarily to the education and healthcare sectors. The platform enables users, including international students and patients seeking medical care abroad, to make payments in various currencies through familiar online and offline options. By leveraging vertical-specific insights and technology, Flywire streamlines the payment process and enhances operational efficiency while minimizing risks associated with invoicing and payment reconciliation. The company, which was founded in 2009 and is headquartered in Boston, Massachusetts, has established partnerships with TRUE North and Adyen to bolster its offerings. With a significant portion of its revenue generated from the Americas, Flywire continues to expand its services to meet the needs of its diverse clientele.
ViewRay, Inc. specializes in the design, manufacture, and marketing of advanced radiation therapy systems, particularly the MRIdian system, which is the first MRI-guided radiation therapy technology that allows simultaneous imaging and treatment of cancer patients. This innovative system integrates MRI technology with radiation delivery and proprietary software, enabling clinicians to accurately locate, target, and track soft-tissue tumors during treatment. By providing real-time imaging, MRIdian enhances visibility of tumors, thus allowing for precise radiation delivery while minimizing exposure to surrounding healthy tissue. This capability addresses significant limitations of traditional external-beam radiation therapies and expands treatment options for patients who may not have been eligible for radiation therapy previously. ViewRay serves a diverse client base, including university hospitals, community hospitals, and freestanding cancer centers, through a direct sales force and distribution network. The company, founded in 2004 and headquartered in Oakwood, Ohio, has operations in the United States and several European countries.
Fluidnet was founded in 2002 by a group of medical device professionals who collectively have over 100+ years of industry experience and product innovations. Based on the seacoast of scenic New Hampshire, Fluidnet is just north of Boston, providing access to a rich medical device community and first-rate research and development skills and facilities.
NextWave Pharmaceuticals is a Cupertino, California-based pharmaceutical company that specializes in the development and commercialization of innovative drug delivery technologies. The company primarily focuses on creating once-daily liquid medications for the treatment of attention deficit/hyperactivity disorder (ADHD). By leveraging its proprietary technology, NextWave aims to provide effective treatment options that enhance patient compliance and address disorders related to the central nervous system.
ViewRay, Inc. specializes in the design, manufacture, and marketing of advanced radiation therapy systems, particularly the MRIdian system, which is the first MRI-guided radiation therapy technology that allows simultaneous imaging and treatment of cancer patients. This innovative system integrates MRI technology with radiation delivery and proprietary software, enabling clinicians to accurately locate, target, and track soft-tissue tumors during treatment. By providing real-time imaging, MRIdian enhances visibility of tumors, thus allowing for precise radiation delivery while minimizing exposure to surrounding healthy tissue. This capability addresses significant limitations of traditional external-beam radiation therapies and expands treatment options for patients who may not have been eligible for radiation therapy previously. ViewRay serves a diverse client base, including university hospitals, community hospitals, and freestanding cancer centers, through a direct sales force and distribution network. The company, founded in 2004 and headquartered in Oakwood, Ohio, has operations in the United States and several European countries.
Tetraphase Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing and commercializing novel antibiotics to combat serious multidrug-resistant infections. Its primary product candidate, Xerava (eravacycline), is a synthetic fluorocycline designed for intravenous use as a first-line treatment for multidrug-resistant infections, particularly those caused by Gram-negative bacteria. The company has conducted Phase III clinical trials, including IGNITE1 and IGNITE4, to evaluate Xerava's safety and efficacy for treating complicated intra-abdominal infections. In addition to Xerava, Tetraphase is advancing other product candidates, such as TP-271, which targets respiratory diseases caused by antibiotic-resistant pathogens, and TP-6076, aimed at treating multidrug-resistant Gram-negative infections. The company holds a licensing agreement with Everest Medicines Limited to develop and commercialize Xerava in various Asian markets. Founded in 2006 and headquartered in Watertown, Massachusetts, Tetraphase Pharmaceuticals is a subsidiary of La Jolla Pharmaceutical Company.
Ironwood Pharmaceuticals, Inc. is a healthcare company headquartered in Boston, Massachusetts, specializing in the development and commercialization of gastrointestinal products. The company markets linaclotide, a medication used to treat irritable bowel syndrome with constipation and chronic idiopathic constipation, under the brand names LINZESS in the United States and CONSTELLA in Canada and the European Union. Additionally, Ironwood is developing MD-7246, an oral, non-opioid pain relief agent for abdominal pain related to gastrointestinal diseases, and IW 3718, a bile acid sequestrant currently in Phase III trials for gastroesophageal reflux disease (GERD). The company has established collaboration agreements with Allergan and AstraZeneca for the commercialization of linaclotide across various regions, including North America and Asia, and a licensing agreement with Astellas Pharma for the Japanese market. Founded in 1998, Ironwood Pharmaceuticals was previously known as Microbia, Inc. and has evolved to focus on addressing significant unmet needs in gastrointestinal and other therapeutic areas.