Amkey Ventures

Amkey Ventures is a California-based VC firm, and their mission is to identify investment opportunities by focusing on cutting-edge biomedical technologies. Amkey manages 2 funds for Amkey Venture Capital, Inc., and Amkey Biotechnology Venture Capital, Inc.. The portfolio companies include medical devices, drug development, antibody, GPCR reagent and stem cell.

George J. Lee

Managing Director and Founder

12 past transactions

Cardiva Medical

Venture Round in 2014
Cardiva Medical, Inc. is a medical device company that specializes in vascular access management products designed to facilitate the body's healing process after catheterization procedures. The company offers several innovative products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications. Additionally, Cardiva Medical provides the Cardiva CATALYST, a manual compression assistance device that enhances coagulation for patients requiring temporary hemostasis. Another key product is the VASCADE MVP, which is used for multi-site venous closure during electrophysiology procedures, such as cardiac ablation. Founded in 2002 and headquartered in Santa Clara, California, Cardiva Medical serves physicians and cardiac centers throughout the United States, focusing on transforming vascular closure practices to improve patient outcomes.

Apexigen

Series A in 2013
Apexigen Inc. is a clinical-stage biopharmaceutical company based in San Carlos, California, dedicated to the discovery and development of antibody therapeutics for cancer treatment. The company focuses on creating innovative immuno-oncology products that leverage the patient's immune system to effectively combat and eliminate cancer. Apexigen's therapeutic pipeline includes several candidates such as APX005M and APX201 for immuno-oncology, alongside APX003 and TRK-950 for oncology, as well as APX001 for inflammation and APX003 for ocular diseases. Additionally, the company has developed the APXiMAB platform, which facilitates the discovery of antibodies targeting novel immune system components. Founded in 2010, Apexigen aims to advance next-generation therapies that address significant unmet needs in cancer treatment.

Cardiva Medical

Venture Round in 2012
Cardiva Medical, Inc. is a medical device company that specializes in vascular access management products designed to facilitate the body's healing process after catheterization procedures. The company offers several innovative products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications. Additionally, Cardiva Medical provides the Cardiva CATALYST, a manual compression assistance device that enhances coagulation for patients requiring temporary hemostasis. Another key product is the VASCADE MVP, which is used for multi-site venous closure during electrophysiology procedures, such as cardiac ablation. Founded in 2002 and headquartered in Santa Clara, California, Cardiva Medical serves physicians and cardiac centers throughout the United States, focusing on transforming vascular closure practices to improve patient outcomes.

Cardiva Medical

Venture Round in 2011
Cardiva Medical, Inc. is a medical device company that specializes in vascular access management products designed to facilitate the body's healing process after catheterization procedures. The company offers several innovative products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications. Additionally, Cardiva Medical provides the Cardiva CATALYST, a manual compression assistance device that enhances coagulation for patients requiring temporary hemostasis. Another key product is the VASCADE MVP, which is used for multi-site venous closure during electrophysiology procedures, such as cardiac ablation. Founded in 2002 and headquartered in Santa Clara, California, Cardiva Medical serves physicians and cardiac centers throughout the United States, focusing on transforming vascular closure practices to improve patient outcomes.

Cardiva Medical

Series D in 2008
Cardiva Medical, Inc. is a medical device company that specializes in vascular access management products designed to facilitate the body's healing process after catheterization procedures. The company offers several innovative products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications. Additionally, Cardiva Medical provides the Cardiva CATALYST, a manual compression assistance device that enhances coagulation for patients requiring temporary hemostasis. Another key product is the VASCADE MVP, which is used for multi-site venous closure during electrophysiology procedures, such as cardiac ablation. Founded in 2002 and headquartered in Santa Clara, California, Cardiva Medical serves physicians and cardiac centers throughout the United States, focusing on transforming vascular closure practices to improve patient outcomes.

Multispan

Series B in 2007
Multispan, Inc. is a biotechnology company based in Hayward, California, specializing in drug discovery research focused on G-protein coupled receptors (GPCRs). Established in 2004, the company has developed a comprehensive collection of human GPCR clones and high-expression cell lines, including its proprietary HExTM series, which are utilized for high-throughput screening. Multispan offers a range of services, including custom compound profiling, cell line generation, and monoclonal antibody development, along with frozen cell and membrane preparation. Additionally, the company develops therapeutic antibody leads targeting inflammatory diseases and cancer, providing researchers with tools and support from assay design through implementation.

Cardiva Medical

Series C in 2006
Cardiva Medical, Inc. is a medical device company that specializes in vascular access management products designed to facilitate the body's healing process after catheterization procedures. The company offers several innovative products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications. Additionally, Cardiva Medical provides the Cardiva CATALYST, a manual compression assistance device that enhances coagulation for patients requiring temporary hemostasis. Another key product is the VASCADE MVP, which is used for multi-site venous closure during electrophysiology procedures, such as cardiac ablation. Founded in 2002 and headquartered in Santa Clara, California, Cardiva Medical serves physicians and cardiac centers throughout the United States, focusing on transforming vascular closure practices to improve patient outcomes.

VM Discovery

Series B in 2006
VM Discovery, Inc. is a drug design and discovery company based in Fremont, California, founded in 2001. The company specializes in providing drug design and optimization services that help clients identify multi-property optimized drug candidates. VM Discovery employs advanced technology for comprehensive parallel multi-property and activity modeling, optimization, and virtual screening. This enables the selection of new and improved small molecule drug candidates with balanced potency. VM Discovery collaborates with pharmaceutical and biotechnology companies in the United States and Asia, also offering internally optimized drug candidates to enhance the drug development process.

Multispan

Series A in 2004
Multispan, Inc. is a biotechnology company based in Hayward, California, specializing in drug discovery research focused on G-protein coupled receptors (GPCRs). Established in 2004, the company has developed a comprehensive collection of human GPCR clones and high-expression cell lines, including its proprietary HExTM series, which are utilized for high-throughput screening. Multispan offers a range of services, including custom compound profiling, cell line generation, and monoclonal antibody development, along with frozen cell and membrane preparation. Additionally, the company develops therapeutic antibody leads targeting inflammatory diseases and cancer, providing researchers with tools and support from assay design through implementation.

VM Discovery

Series A in 2004
VM Discovery, Inc. is a drug design and discovery company based in Fremont, California, founded in 2001. The company specializes in providing drug design and optimization services that help clients identify multi-property optimized drug candidates. VM Discovery employs advanced technology for comprehensive parallel multi-property and activity modeling, optimization, and virtual screening. This enables the selection of new and improved small molecule drug candidates with balanced potency. VM Discovery collaborates with pharmaceutical and biotechnology companies in the United States and Asia, also offering internally optimized drug candidates to enhance the drug development process.

VM Discovery

Series A in 2003
VM Discovery, Inc. is a drug design and discovery company based in Fremont, California, founded in 2001. The company specializes in providing drug design and optimization services that help clients identify multi-property optimized drug candidates. VM Discovery employs advanced technology for comprehensive parallel multi-property and activity modeling, optimization, and virtual screening. This enables the selection of new and improved small molecule drug candidates with balanced potency. VM Discovery collaborates with pharmaceutical and biotechnology companies in the United States and Asia, also offering internally optimized drug candidates to enhance the drug development process.

Renal Solutions

Series A in 2002
Renal Solutions is a company based in Warrendale, Pennsylvania, that specializes in the development of dialysis products and services. Founded in 2000 and acquired by Fresenius Medical Care in 2007, the company focuses on creating integrated medical devices for sorbent hemodialysis treatment. These devices provide a clinical care model tailored for patients with chronic and acute kidney failure, allowing healthcare practitioners to offer flexible and convenient treatment options. Renal Solutions aims to enhance renal care through innovative sorbent-based dialysis technologies.
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