Astrocyte Pharmaceuticals
Series B in 2023
Astrocyte Pharmaceuticals Inc. is a drug development company focused on creating neuroprotection therapies for various brain injuries, including traumatic brain injuries, concussions, acute ischemic strokes, and neurodegenerative disorders like Alzheimer’s disease. Founded in 2014 and located in Cambridge, Massachusetts, the company is dedicated to demonstrating the neuroprotective benefits of selective astrocyte activation. Its lead product, AST-004, is a novel small molecule designed for acute administration that protects and repairs damaged neurons by selectively stimulating astrocytes. Astrocyte Pharmaceuticals aims to advance innovative therapeutic agents to improve recovery and well-being for patients suffering from brain injuries.
Astrocyte Pharmaceuticals
Series A in 2021
Astrocyte Pharmaceuticals Inc. is a drug development company focused on creating neuroprotection therapies for various brain injuries, including traumatic brain injuries, concussions, acute ischemic strokes, and neurodegenerative disorders like Alzheimer’s disease. Founded in 2014 and located in Cambridge, Massachusetts, the company is dedicated to demonstrating the neuroprotective benefits of selective astrocyte activation. Its lead product, AST-004, is a novel small molecule designed for acute administration that protects and repairs damaged neurons by selectively stimulating astrocytes. Astrocyte Pharmaceuticals aims to advance innovative therapeutic agents to improve recovery and well-being for patients suffering from brain injuries.
Coviu
Venture Round in 2020
Coviu is a telehealth startup that provides a video telehealth platform designed to enhance online health consultations for various medical specialties, including cardiology, dermatology, and psychology, among others. The platform offers an integrated video service that features a marketplace of clinical tools, which can be developed internally or through external partnerships via its application programming interface. Coviu enables healthcare practitioners to conduct video consultations that are supported by a range of in-call clinical tools, ensuring that the experience is as effective as an in-person visit. The software is compatible with various practice management systems, allowing for seamless integration and access to validated clinical resources from any consumer device.
Capillary Biomedical
Seed Round in 2018
Capillary Biomedical, Inc. is a medical device company based in Irvine, California, established in 2014 as a spin-out from the Artificial Pancreas Center at the Sidney Kimmel Medical College. The company focuses on developing innovative technologies for diabetes management, aiming to simplify the processes of glucose monitoring and insulin delivery. Their signature product features a kink-proof, flexible, multiport cannula designed to enhance the reliability and comfort of insulin delivery. This user-friendly device allows for simple one-handed insertion, enabling diabetes patients to better manage their blood glucose levels and alleviating some of the burdens associated with diabetes on both individuals and the healthcare system.
Astrocyte Pharmaceuticals
Seed Round in 2018
Astrocyte Pharmaceuticals Inc. is a drug development company focused on creating neuroprotection therapies for various brain injuries, including traumatic brain injuries, concussions, acute ischemic strokes, and neurodegenerative disorders like Alzheimer’s disease. Founded in 2014 and located in Cambridge, Massachusetts, the company is dedicated to demonstrating the neuroprotective benefits of selective astrocyte activation. Its lead product, AST-004, is a novel small molecule designed for acute administration that protects and repairs damaged neurons by selectively stimulating astrocytes. Astrocyte Pharmaceuticals aims to advance innovative therapeutic agents to improve recovery and well-being for patients suffering from brain injuries.
Lantos
Venture Round in 2018
Lantos Technologies, Inc., established in 2009 and headquartered in Derry, New Hampshire, specializes in developing advanced 3D digital ear scanning technology. The company offers the FDA-cleared AURA system, which captures comprehensive data from the outer ear to deep within the ear canal, enabling designers to create personalized in-ear devices with superior comfort and sound quality. This includes custom in-ear headphones, musicians' monitors, hearing aids, and noise protection solutions. Lantos' technology enhances clinical efficiency for audiologists by providing precise measurements, improving patient outcomes, and streamlining the process for faster turnaround times on custom devices.
Astrocyte Pharmaceuticals
Seed Round in 2017
Astrocyte Pharmaceuticals Inc. is a drug development company focused on creating neuroprotection therapies for various brain injuries, including traumatic brain injuries, concussions, acute ischemic strokes, and neurodegenerative disorders like Alzheimer’s disease. Founded in 2014 and located in Cambridge, Massachusetts, the company is dedicated to demonstrating the neuroprotective benefits of selective astrocyte activation. Its lead product, AST-004, is a novel small molecule designed for acute administration that protects and repairs damaged neurons by selectively stimulating astrocytes. Astrocyte Pharmaceuticals aims to advance innovative therapeutic agents to improve recovery and well-being for patients suffering from brain injuries.
Sentien Biotechnologies
Series A in 2017
Sentien Biotechnologies, Inc. is a clinical-stage biotechnology company focused on developing innovative cell therapies aimed at restoring immune system balance and improving treatment options for patients with systemic inflammatory diseases. The company specializes in proprietary cell compositions and Good Manufacturing Practice (GMP) manufacturing methods that enhance the efficacy of cell therapy. Its flagship product, SBI-101, utilizes an extracorporeal device to immobilize Mesenchymal Stromal Cells (MSCs), facilitating sustained and controlled delivery of their therapeutic properties, which include anti-inflammatory and regenerative effects. Additionally, the company offers the Sentinel device, designed to treat patients during dialysis by supplementing their blood with MSC-derived secretions that address immune dysfunction and promote tissue repair. Founded in 2008, Sentien Biotechnologies is headquartered in Medford, Massachusetts.
Sentieon, Inc. is a bioinformatics company based in Mountain View, California, founded in 2014. It specializes in developing and commercializing cloud-based solutions for the life sciences and clinical markets. Sentieon offers a range of bioinformatics tools designed for processing genomics data with a focus on accuracy, efficiency, and quick turnaround times. Its notable products include Sentieon DNAseq, which aids in germline DNA analysis, and Sentieon TNseq, designed for detecting tumor-normal somatic variants. These software-only tools boast scalability and upgradeability, leveraging optimized algorithms to improve computing performance. Sentieon aims to enhance the capabilities of scientists and clinicians by providing precision tools that facilitate comprehensive tumor characterization and other critical bioinformatics processes.
Parsagen
Venture Round in 2014
Parsagen Diagnostics is comprised of a team of passionate and driven leaders who have a proven ability to bring a product from conception through commercialization in multiple global markets. As they expand their presence in the US & abroad, they are looking for people who exhibit flexibility under pressure, who have a proclivity to seek & approach challenges with optimism and grit, and who can identify areas of need and contribute to their ultimate fulfillment.
InfoBionic
Series B in 2014
InfoBionic, Inc., incorporated in 2011 and based in Lowell, Massachusetts, specializes in remote patient monitoring technologies, particularly focusing on cardiac arrhythmia detection. The company has developed the MoMe System, a cloud-based platform that allows for continuous monitoring of electrocardiogram, respiration, and motion data. This wireless system streamlines the remote patient monitoring process, enhancing both clinical efficiency and patient care by enabling healthcare providers to access patient data anytime and anywhere. InfoBionic's innovative approach aims to transform the economics of cardiac diagnostic services, benefiting both physicians and patients through improved detection and treatment of cardiac complications.
Sialix Cancer Research
Series B in 2014
Sialix Cancer Research provides cancer susceptibility antibodies and cancer-associated nucleoprotein antibodies for breast cancer. They also offer laser-based photodynamic endoscopic diagnosis using 5-aminolevulinic acid for early gastric adenocarcinoma and gastric adenoma.
Siamab Therapeutics
Series B in 2014
Siamab Therapeutics is a biopharmaceutical company based in Newton, Massachusetts, focused on developing therapies for cancers that express abnormal carbohydrates or glycans. The company's technology platform facilitates the discovery of anti-tumor-associated carbohydrate antigen (anti-TACA) therapeutic antibodies. Siamab Therapeutics' pipeline includes ST1, a program targeting a tumor-associated carbohydrate antigen found in various solid tumors such as ovarian, prostate, pancreatic, gastric, and colon cancers. The company has a strategic collaboration with Boehringer Ingelheim and was founded in 2006. Its core technologies were licensed from the laboratory of Ajit Varki, an expert in glycobiology and sialic-acid biochemistry.
Siamab Therapeutics
Series B in 2013
Siamab Therapeutics is a biopharmaceutical company based in Newton, Massachusetts, focused on developing therapies for cancers that express abnormal carbohydrates or glycans. The company's technology platform facilitates the discovery of anti-tumor-associated carbohydrate antigen (anti-TACA) therapeutic antibodies. Siamab Therapeutics' pipeline includes ST1, a program targeting a tumor-associated carbohydrate antigen found in various solid tumors such as ovarian, prostate, pancreatic, gastric, and colon cancers. The company has a strategic collaboration with Boehringer Ingelheim and was founded in 2006. Its core technologies were licensed from the laboratory of Ajit Varki, an expert in glycobiology and sialic-acid biochemistry.
Avaxia Biologics
Series B in 2013
Avaxia Biologics, Inc. is a biopharmaceutical company based in Lexington, Massachusetts, focused on developing oral antibody therapeutics for a range of gastrointestinal diseases. Founded in 2005, the company utilizes a proprietary antibody platform to create treatments for conditions such as inflammatory bowel disease, celiac disease, necrotizing enterocolitis, radiation syndrome, oral mucositis, and type 2 diabetes. By concentrating on gut-targeted therapeutics, Avaxia aims to improve treatment options for patients suffering from these serious ailments. The company has established a strategic collaboration with Courtagen Life Sciences to enhance its product development efforts. Avaxia Biologics operates as a subsidiary of Circle33 LLC.
Avaxia Biologics
Series B in 2012
Avaxia Biologics, Inc. is a biopharmaceutical company based in Lexington, Massachusetts, focused on developing oral antibody therapeutics for a range of gastrointestinal diseases. Founded in 2005, the company utilizes a proprietary antibody platform to create treatments for conditions such as inflammatory bowel disease, celiac disease, necrotizing enterocolitis, radiation syndrome, oral mucositis, and type 2 diabetes. By concentrating on gut-targeted therapeutics, Avaxia aims to improve treatment options for patients suffering from these serious ailments. The company has established a strategic collaboration with Courtagen Life Sciences to enhance its product development efforts. Avaxia Biologics operates as a subsidiary of Circle33 LLC.
Diffinity Genomics
Series B in 2012
Diffinity Genomics, Inc. is a biotechnology company specializing in the development of innovative products for nucleic acid isolation and analysis. Founded in 2005 and headquartered in West Henrietta, New York, the company creates single-use disposable items designed for medical, industrial, and research applications. Among its offerings is RapidTip, a functional pipette tip that facilitates the purification of polymerase chain reaction (PCR) amplicons, along with various products aimed at optimizing DNA purification and preparation for downstream applications. Diffinity Genomics serves a diverse clientele, including life science professionals engaged in DNA analysis, as well as academic and industrial laboratories across the globe.
Avaxia Biologics
Series A in 2012
Avaxia Biologics, Inc. is a biopharmaceutical company based in Lexington, Massachusetts, focused on developing oral antibody therapeutics for a range of gastrointestinal diseases. Founded in 2005, the company utilizes a proprietary antibody platform to create treatments for conditions such as inflammatory bowel disease, celiac disease, necrotizing enterocolitis, radiation syndrome, oral mucositis, and type 2 diabetes. By concentrating on gut-targeted therapeutics, Avaxia aims to improve treatment options for patients suffering from these serious ailments. The company has established a strategic collaboration with Courtagen Life Sciences to enhance its product development efforts. Avaxia Biologics operates as a subsidiary of Circle33 LLC.
lifeIMAGE
Series B in 2011
LifeIMAGE is an online network that enables individuals to exchange medical images. LifeIMAGE is interoperable with the hospital EMR to provide integrated access to medical images, from anywhere. Clinicians can exchange medical images with patients and providers, anywhere. It was founded in 2008 and headquartered in Newton, Massachusetts.
Lantos
Venture Round in 2011
Lantos Technologies, Inc., established in 2009 and headquartered in Derry, New Hampshire, specializes in developing advanced 3D digital ear scanning technology. The company offers the FDA-cleared AURA system, which captures comprehensive data from the outer ear to deep within the ear canal, enabling designers to create personalized in-ear devices with superior comfort and sound quality. This includes custom in-ear headphones, musicians' monitors, hearing aids, and noise protection solutions. Lantos' technology enhances clinical efficiency for audiologists by providing precise measurements, improving patient outcomes, and streamlining the process for faster turnaround times on custom devices.
Annovation BioPharma
Venture Round in 2011
Annovation BioPharma develops pharmaceutical products in the field of anesthesia, sedation, and sleep. The company was incorporated in 2009 and is based in Wayland, Massachusetts.
MoMelan Technologies
Series A in 2011
MoMelan Technologies, Inc. is a company based in Cambridge, Massachusetts, that specializes in developing innovative devices for the treatment of skin disorders. Established in 2009, the company focuses on a tabletop device designed to enhance the surface area of skin grafts. By taking a small sample of harvested skin and expanding it by approximately 100 times, the device enables effective grafting onto damaged areas, such as scars. MoMelan Technologies operates as a subsidiary of Acelity L.P. Inc., further emphasizing its commitment to advancing medical solutions in dermatology.
Bliss Health
Seed Round in 2011
Bliss Health offers care management services through a network of integrated medical, nursing, and home care services.
Polytouch Medical
Seed Round in 2010
Polytouch Medical is dedicated to advancing minimally invasive surgery through the development of innovative solutions for laparoscopic procedures, particularly in hernia repair. The company specializes in hernia mesh placement technologies, with its flagship product, PatchAssist, designed to facilitate the treatment of ventral hernias. By collaborating closely with physicians, Polytouch Medical focuses on enhancing mesh deployment and placement techniques, thereby enabling quicker treatment initiation and increasing the likelihood of successful outcomes for patients. The company prides itself on its dedicated workforce, medical advisors who translate ideas into practical applications, and board members who assist in bringing these products to market.
Lantos
Venture Round in 2010
Lantos Technologies, Inc., established in 2009 and headquartered in Derry, New Hampshire, specializes in developing advanced 3D digital ear scanning technology. The company offers the FDA-cleared AURA system, which captures comprehensive data from the outer ear to deep within the ear canal, enabling designers to create personalized in-ear devices with superior comfort and sound quality. This includes custom in-ear headphones, musicians' monitors, hearing aids, and noise protection solutions. Lantos' technology enhances clinical efficiency for audiologists by providing precise measurements, improving patient outcomes, and streamlining the process for faster turnaround times on custom devices.
lifeIMAGE
Series A in 2009
LifeIMAGE is an online network that enables individuals to exchange medical images. LifeIMAGE is interoperable with the hospital EMR to provide integrated access to medical images, from anywhere. Clinicians can exchange medical images with patients and providers, anywhere. It was founded in 2008 and headquartered in Newton, Massachusetts.
Daktari Diagnostics
Series A in 2009
Daktari Diagnostics, Inc. is a healthcare solutions company based in Cambridge, Massachusetts, focused on developing portable point-of-care diagnostic platforms to enhance disease management globally. Founded in 2008, the company offers several innovative products, including Daktari Virology for the detection of Hepatitis C and HIV, Daktari InSight, a cloud-based data management service, and Daktari Sickle Cell, which identifies infants with sickle cell disease from a single drop of blood. Daktari’s technology is designed specifically for resource-poor markets, featuring built-in wireless connectivity that facilitates real-time data sharing among healthcare providers. By delivering critical diagnostic information efficiently, Daktari aims to improve clinical outcomes and support global health initiatives. The company's commitment to affordability and quality ensures that its products are accessible to healthcare professionals and patients worldwide.