Sampling Human specializes in developing advanced technologies for genetic analysis, focusing on complex single-cell and spatial omic data. The company aims to create compute-driven products that facilitate the measurement and analysis of this data at an industrial scale. Through its innovative solutions, Sampling Human supports various applications in pre-symptomatic screening, personalized medicine, drug discovery, and basic science. This approach enables healthcare professionals to effectively translate extensive datasets into practical applications in diagnostics and bioengineering, ultimately enhancing the capabilities of physicians in addressing complex medical challenges.
Turn.bio is a biotechnology company focused on developing drugs aimed at reversing aging and age-related diseases. Leveraging its patented mRNA platform technology, known as ERA, the company addresses the effects of aging on the epigenome, thereby restoring optimal gene expression. Turn.bio’s innovative approach enables the body to heal itself by instructing specific cells to combat diseases or repair damaged tissues. The company targets a range of medical indications, including immune-related diseases such as cancer, dermatological conditions, ophthalmology, osteoarthritis, and issues related to the muscular system. Through its advanced delivery platform, eTurna, Turn.bio seeks to enhance the effectiveness of nucleic acid therapeutics in promoting health and longevity.
Aviron Ltd engages in the research and development of specific antiviral agents against chronic Hepatitis C Virus (HCV) infection. The company has strategic alliances with CHEMRAR Hi-Tech Center, Chemical Diversity Research Institute, and DRUGS TECHNOLOGY, Ltd. Aviron Ltd was founded in 2010 and is based in Moscow, Russian Federation.
Aviron Interactive is a fitness company that specializes in innovative rowing machines designed for home use. Their rowers incorporate gamification features, allowing users to engage in short, high-intensity workouts that combine cardio and strength training. With smart resistance settings and various workout programs curated by experienced trainers, Aviron provides a diverse range of options to keep users motivated and engaged. The company's focus on delivering an interactive fitness experience differentiates it from traditional workout regimes, making fitness more accessible and enjoyable for clients.
Framework is a company focused on creating environmentally friendly consumer electronics, with a strong emphasis on upgradeability, customization, and repairability. Their inaugural product, the Framework Laptop 13, garnered significant acclaim, including recognition on the cover of TIME's Best Inventions of 2021. In 2023, they expanded their product line with the Framework Laptop 16, a high-performance notebook that offers customizable inputs and modular, upgradeable graphics. Framework's approach allows consumers to easily modify and assemble their devices without needing professional assistance, promoting sustainability and consumer empowerment in the electronics market.
MultiOmic Health is an AI-driven start-up specializing in drug discovery for metabolic syndrome-related diseases. The company collaborates with selected healthcare providers to collect and analyze de-identified patient data and bio-samples. Its MOHSAIC® platform integrates multi-omics analysis with computational systems biology modeling and targeted laboratory experiments to develop novel precision therapeutic concepts. These concepts are then commercialized through partnerships with established biopharma companies, facilitating the creation of new therapeutic and diagnostic research and development programs. By focusing on precision medicine, MultiOmic Health aims to improve treatment options for patients suffering from metabolic syndrome.
Xcell Biosciences, Inc. is a San Francisco-based life science start-up founded in 2012, focused on developing innovative technologies for cancer cell analysis and immunotherapy. The company specializes in a bench-top primary cell control system that captures, grows, and analyzes cancer cells directly from patient blood samples. Their proprietary technology allows for precise control of primary cell phenotype and function, enhancing the efficacy and persistence of immune cell therapies. By supporting various primary cell types, including immune, stem, and tumor cells, Xcell Biosciences provides researchers with advanced tools for cell maintenance and expansion, ultimately aiming to improve therapy development and clinical outcomes.
Aviron Interactive is a fitness company that specializes in innovative rowing machines designed for home use. Their rowers incorporate gamification features, allowing users to engage in short, high-intensity workouts that combine cardio and strength training. With smart resistance settings and various workout programs curated by experienced trainers, Aviron provides a diverse range of options to keep users motivated and engaged. The company's focus on delivering an interactive fitness experience differentiates it from traditional workout regimes, making fitness more accessible and enjoyable for clients.
Framework is a company focused on creating environmentally friendly consumer electronics, with a strong emphasis on upgradeability, customization, and repairability. Their inaugural product, the Framework Laptop 13, garnered significant acclaim, including recognition on the cover of TIME's Best Inventions of 2021. In 2023, they expanded their product line with the Framework Laptop 16, a high-performance notebook that offers customizable inputs and modular, upgradeable graphics. Framework's approach allows consumers to easily modify and assemble their devices without needing professional assistance, promoting sustainability and consumer empowerment in the electronics market.
Scribe Biosciences specializes in single-cell analysis tools that enhance clinical and research applications. The company employs its proprietary technology, Printed Droplet Microfluidics (PDM), which allows for flexible and reconfigurable fluid handling at the picoliter scale. By utilizing fluorescence-activated microfluidic droplet sorting along with a specialized substrate, Scribe Biosciences can manipulate single cells and fluid aliquots with high throughput. This innovative approach aids researchers and healthcare professionals in gaining insights into various processes, particularly those related to infectious diseases and cancer.
Turn.bio is a biotechnology company focused on developing drugs aimed at reversing aging and age-related diseases. Leveraging its patented mRNA platform technology, known as ERA, the company addresses the effects of aging on the epigenome, thereby restoring optimal gene expression. Turn.bio’s innovative approach enables the body to heal itself by instructing specific cells to combat diseases or repair damaged tissues. The company targets a range of medical indications, including immune-related diseases such as cancer, dermatological conditions, ophthalmology, osteoarthritis, and issues related to the muscular system. Through its advanced delivery platform, eTurna, Turn.bio seeks to enhance the effectiveness of nucleic acid therapeutics in promoting health and longevity.
Nanome Inc. is a software company based in North Hollywood, California, founded in 2015. It specializes in developing a collaborative XR software platform that enhances scientific discovery through the use of virtual reality and blockchain technologies. This platform streamlines computational workflows at the molecular level, enabling a broader range of scientists to utilize advanced molecular computations and artificial intelligence. Nanome primarily collaborates with the biopharma industry but also extends its services to sectors such as food and beverage, material science, and education. The company's open-source platform allows scientists to explore molecular structures effectively, facilitating pattern recognition, molecular visualization, and an efficient drug design and discovery process. Additionally, it helps medicinal chemists and structural biologists understand complex molecular data, collaborate more effectively, and protect their intellectual property through blockchain integration.
Wambi is a healthcare technology company that focuses on improving the quality of care in hospital and healthcare settings. The company offers a digital management and recognition platform designed to enhance workforce engagement and streamline recognition processes. By addressing clinician burnout and fostering a supportive environment, Wambi aims to boost employee engagement and overall patient experience. Additionally, Wambi provides a real-time patient feedback platform, allowing healthcare organizations to gather valuable insights for continuous improvement. The company’s services reflect a commitment to dignity and respect in healthcare, ultimately contributing to better outcomes for both patients and providers.
Deep Longevity, Inc. is a biotechnology company focused on advancing aging and longevity research through the development of aging clocks and biomarkers. Founded in 2016 and based in Hong Kong, the company offers a range of products including the Longevity Cloud, which hosts deep aging clocks, and Young.AI, a web and mobile application designed to assist individuals in monitoring their biological age. Deep Longevity also provides AgeMetric Reports for tracking longevity and employs an AI-based recommendation engine to suggest interventions for improving health outcomes. Its comprehensive approach incorporates various data types such as clinical blood tests, transcriptomic, proteomic, and microbiome information, enabling healthcare providers and aging centers to predict biological age with greater accuracy and support preventative medicine initiatives.
Angion Biomedica Corp. is a clinical-stage biopharmaceutical company dedicated to discovering and developing small molecule therapeutics aimed at treating acute organ injuries and fibrotic diseases, particularly focusing on renal conditions. The company is advancing several product candidates, including BB3, which is undergoing phase 3 trials for delayed graft function following kidney transplants and phase 2 trials for acute kidney injury related to open-heart surgery. Another key candidate, ANG-3070, is an orally bioavailable fibrokinase inhibitor designed for chronic kidney disease and polycystic kidney disease. Additionally, Angion is exploring other compounds targeting renal disease and fibrosis, such as ANG-3586 and ANG-4021. Founded in 1998, Angion is headquartered in San Francisco, California, with research facilities in New York and clinical operations in Boston.
Volumetric, Inc. is a Houston-based company that specializes in advanced biomaterials and biofabrication through its innovative 3D bioprinting platform. Founded in 2014, Volumetric focuses on creating vascularized human tissue and developing bioprinters and bio inks for a range of applications, including life sciences, drug discovery, and medical devices. The company's technology aims to enhance research in biomaterials, cancer treatments, and the potential replacement of human organs, positioning it at the forefront of developments in regenerative medicine and tissue engineering.
Underdog Pharmaceuticals is pursuing a mission to treat the underlying causes of age-related disease. The company develops simple and direct interventions targeting toxic forms of cholesterol, using rationally designed molecules, to provide the first true disease-modifying treatments for age-related diseases such as atherosclerosis, hypercholesterolemia, heart failure, and macular degeneration. Its products are based on novel derivatives of a well-known, safe compound, and a new way of looking at cardiovascular disease created through a SENS Research Foundation program.
Gordian Biotechnology, Inc. is a therapeutics company based in San Francisco, California, founded in 2018. The company specializes in developing a novel screening platform aimed at enhancing the efficiency of drug development for complex age-related diseases. Through its gene therapy discovery platform, Gordian focuses on researching and creating therapeutic drugs that address issues associated with premature aging, ultimately enabling medical professionals to treat age-related conditions and improve patient outcomes, including skin health.
Insilico Medicine, Inc. is a biotechnology company that utilizes artificial intelligence to advance drug discovery, biomarker development, and research into aging. Founded in 2014 and based in Baltimore, Maryland, the company has developed a comprehensive AI platform that employs techniques such as generative adversarial networks and reinforcement learning to create novel molecular structures aimed at treating cancer and age-related diseases. Insilico Medicine operates various projects, including Pharma.AI, which offers machine learning services to biotechnology and pharmaceutical companies, and Young.AI, which predicts biological age. The company is actively engaged in internal drug discovery efforts targeting conditions like Alzheimer's disease, Parkinson's disease, and diabetes, and has partnered with Life Extension to produce nutraceutical products using advanced bioinformatics. Additionally, Insilico Medicine provides consumer applications and services to academic institutions and the cosmetic industry, solidifying its role in the intersection of AI and healthcare.
Turn.bio is a biotechnology company focused on developing drugs aimed at reversing aging and age-related diseases. Leveraging its patented mRNA platform technology, known as ERA, the company addresses the effects of aging on the epigenome, thereby restoring optimal gene expression. Turn.bio’s innovative approach enables the body to heal itself by instructing specific cells to combat diseases or repair damaged tissues. The company targets a range of medical indications, including immune-related diseases such as cancer, dermatological conditions, ophthalmology, osteoarthritis, and issues related to the muscular system. Through its advanced delivery platform, eTurna, Turn.bio seeks to enhance the effectiveness of nucleic acid therapeutics in promoting health and longevity.
Encellin develops a novel thin-film cell encapsulation device for cell-based therapeutics. It has dedicated experts focused on the investigation and advancement of next-generation therapies. It aims to help patients with chronic diseases, starting with Type 1 diabetes. It was founded in 2016 and is headquartered in San Francisco, California.
Arctoris Limited is a biotechnology company based in Oxford, United Kingdom, with additional operations in Boston and Singapore. Founded in 2016, Arctoris has developed an automated drug discovery platform that combines advanced robotics and data science to facilitate cellular and molecular biology experiments. The platform allows researchers and biotech entrepreneurs to design experiments online and receive detailed results and reports, enhancing their ability to make informed decisions. Arctoris actively engages in drug discovery programs, particularly in oncology and neurology, while also providing access to its platform for select biotech and pharmaceutical partners. By leveraging artificial intelligence and robotics, Arctoris aims to generate high-quality data from various assays, thereby accelerating the progression of drug discovery programs toward clinical application.
Schrödinger develops a computational platform that facilitates the research efforts of biopharmaceutical and industrial companies, academic institutions, and government laboratories worldwide. Schrödinger also has wholly-owned and collaborative drug discovery programs in a broad range of therapeutic areas. Schrödinger is deeply committed to investing in the science and talent that drive its computational platform.
Elevian, Inc. is a biotechnology company based in Menlo Park, California, founded in 2017. The company focuses on developing medicines that aim to restore regenerative capacity and address age-related diseases. Elevian's research centers on the Growth Differentiation Factor 11 (GDF11) protein and other circulating blood factors that stimulate regeneration in various tissues, including the brain, heart, pancreas, and muscle. Its therapeutics are designed to target the underlying mechanisms of aging, with applications in stroke recovery, Alzheimer's disease, coronary artery disease, and Type 2 diabetes. Through its innovative approach, Elevian seeks to prevent and treat the effects of aging by enhancing the body's natural repair and regeneration processes.
Juvenescence Limited is a British Virgin Islands-based holding company focused on investing in human aging and longevity. The company has raised substantial funds to establish an ecosystem aimed at developing therapeutics that address aging, age-related diseases, and regeneration. Juvenescence operates under the belief that recent advancements in science and medicine will facilitate the creation of treatments that can significantly extend human healthspan and lifespan. By in-licensing compounds from academia and industry and forming partnerships with leading longevity scientists and research institutions, Juvenescence strives to develop evidence-based therapies targeting the biological causes of aging. The company's initiatives encompass a range of areas, including healthy aging, metabolic health, and brain health, with the objective of halting or potentially reversing aspects of aging. Through its efforts, Juvenescence aims to have a meaningful impact on healthcare and other sectors by promoting both longevity and improved quality of life.
HerculesAI is a generative AI company that brings the power of large language models inside the security perimeter of enterprises. Hercules, enables enterprises to quickly create, deploy, and run generative AI apps without compromising security standards.
Bev is a mission-driven brand, Bev is redefining the landscape within male dominated spaces.
Iron Ox, Inc. is a company that specializes in developing robotic systems for sustainable agriculture. Founded in 2015 and headquartered in San Carlos, California, Iron Ox operates greenhouses in Gilroy, California, and Lockhart, Texas. The company utilizes advanced plant science, machine learning, and robotics to cultivate fresh, pesticide-free produce, including a variety of leafy greens and culinary herbs. One of its key innovations is Angus, an autonomous mobile robot designed for crop harvesting. By integrating technology into farming practices, Iron Ox aims to reduce the environmental impact of agriculture while enhancing the quality and availability of fresh produce for consumers.
Anduril Industries is a defense technology company that designs, manufactures, and deploys advanced hardware and software products to address complex national security challenges for the United States and its allies. Founded in 2017 and headquartered in Irvine, California, the company specializes in developing cutting-edge solutions, including the Lattice Platform—an artificial intelligence system that integrates real-time data into a cohesive operational picture—and the Sentry Tower, which consolidates data from various electromagnetic sources. Additionally, Anduril produces the Ghost sUAS, a man-portable unmanned aerial system capable of executing numerous missions autonomously, and the Anvil sUAS, designed for precision interception of drone threats with human operator verification. Through its innovative technologies, Anduril aims to enhance military capabilities and border surveillance, ensuring the safety and effectiveness of those serving in defense of national interests.
Bolt is a technology company focused on enhancing e-commerce by providing a streamlined checkout experience. Established in 2014 and based in San Francisco, Bolt aims to democratize commerce by enabling retailers to forge stronger relationships with their customers. The company offers a one-click checkout platform that simplifies the purchasing process, allowing shoppers to complete transactions quickly and securely without the need for passwords or re-entering personal information. This efficiency leads to higher conversion rates for retailers. A diverse range of brands, including REVOLVE, Casper, and Benefit Cosmetics, utilize Bolt's services to deliver the fast and seamless checkout experiences that today's online consumers expect.
PRENAV was founded in October 2013 with a goal of solving autonomous flight in complex environments. Since then, they’ve assembled one of the top robotics teams in the world, with experts in computer vision, mechanical engineering, aeronautics, embedded systems, and software. In their short history, they’ve taken their technology to large industrial sites, inspected wind turbines, designed playful light shows, filmed music videos, and traveled around the world for their customers. And they’re only just getting started. At PRENAV, they’re solving fundamental challenges in robotics around localization, materials, planning, and computer vision in order to build autonomous systems that are ready for the real world.