KdT Ventures

PHNX Materials is a manufacturing company that specializes in turning waste into essential materials and reduce carbon emissions.

Character Therapeutics is a patient-driven therapeutics company that uses genomics, longitudinal clinical and imaging data, machine learning, and novel experimental approaches to identify the molecular drivers of disease progression and develop innovative targeted medicines. Its dedication to patients is reflected in the high standards set to ensure privacy, data security, ethics, scientific rigor, and a meaningful impact on patient health. To enable clinical genomic research, the company collaborates with patients, providers, payers, and scientists to create deeply phenotyped patient cohorts.

Montara Therapeutics is a biotechnology company focused on developing innovative therapies for central nervous system diseases. It utilizes a precision pharmacology platform that combines human genetics and machine learning to identify and validate drug targets. This approach aims to enhance the safety and effectiveness of treatments for patients suffering from neurological disorders, ultimately improving therapeutic outcomes in this challenging area of healthcare.

Reverb Therapeutics is focused on creating innovative treatments for cancer and other diseases. The company specializes in developing cytokine therapies that aim to promote targeted immune activation while minimizing toxicity. By utilizing bispecific antibodies, Reverb Therapeutics localizes endogenous cytokines to immune cells within the tumor microenvironment. This approach addresses the toxicity challenges associated with exogenously delivered cytokines, allowing for a more effective use of the body's existing cytokines to target cancer cells. Through this strategy, Reverb Therapeutics seeks to improve outcomes for cancer patients and advance the healthcare sector's capabilities in cancer treatment.

MacroCycle is developing a technology to curb the usage of fossil fuel derived plastic through a circular, sustainable and zero-carbon plastic upcycling process. The company's proprietary process based on the synthesis of cyclic macromolecules enables us to produce virgin-grade recycled PET from plastic waste at lower energy use than traditional processes.

Shiprocket is an eCommerce shipping platform based in New Delhi, India, that was founded in 2017. The company specializes in providing cost-effective shipping solutions for direct-to-consumer retailers. Shiprocket's platform utilizes a machine-learning-based data engine to recommend appropriate courier services, select courier companies, print shipping labels, and track orders from a unified interface. This functionality allows businesses to efficiently manage their shipping and returns processes. Additionally, Shiprocket Packaging offers high-quality packaging materials with a focus on on-time delivery across India, catering to brands and businesses of all sizes.

March Biosciences is a clinical-stage cell therapy company that focuses on developing CAR-T cell strategies to address hematological cancers. The company's lead asset, MB-105, is a CD5-targeted CAR-T cell therapy currently in Phase 1 trials in patients with refractory T-cell lymphoma and leukemia.

Montara Therapeutics is a biotechnology company focused on developing innovative therapies for central nervous system diseases. It utilizes a precision pharmacology platform that combines human genetics and machine learning to identify and validate drug targets. This approach aims to enhance the safety and effectiveness of treatments for patients suffering from neurological disorders, ultimately improving therapeutic outcomes in this challenging area of healthcare.

Marigold Health operates a social network community platform designed to provide text-based group therapies for individuals facing mental health and substance use challenges. The platform facilitates anonymous support groups, allowing patients to engage with one another and receive guidance from coaches who have personal recovery experiences. By leveraging AI-augmented chat support, Marigold Health enhances the capacity of care teams while ensuring that patients receive personalized, stigma-free assistance. The company collaborates directly with treatment providers and managed care organizations within the Medicaid market to improve access to on-demand group therapies and foster a supportive community for recovery.

Radar Therapeutics pioneer in treatment modality, precision-expressed mRNA-based therapeutics.

Elegen is a biotechnology company founded in 2017, focused on developing microfluidic technology to advance synthetic biology. Led by Dr. Matthew Hill, Elegen aims to revolutionize the field by engineering entire genomes and creating innovative DNA synthesizers. Their technology is designed to enhance the speed and efficiency of DNA sequence testing, thereby facilitating significant progress in biomedical research and healthcare applications. Through these efforts, Elegen seeks to contribute to the rapid development of solutions that address various challenges in the life sciences sector.

Motif Neurotech develops minimally invasive bioelectronic implants aimed at monitoring and treating severe mental illnesses, particularly treatment-resistant depression. The company focuses on wireless power and data technologies, which facilitate the creation of new, miniature implants designed for tissue stimulation and diagnostic readings. These innovative implants enable patients to repair neural circuits through electronic therapies, offering a promising approach to address complex mental health challenges.

ZymoChem, Inc. is a biotechnology company based in Emeryville, California, founded in 2013. It specializes in the development of eco-friendly chemicals and bioprocesses using engineered microbes to convert renewable feedstocks, such as sugars, into industrial chemicals. The company’s bio-manufacturing platform aims to produce bio-based materials while minimizing carbon emissions during production, thereby supporting a carbon-efficient economy. By establishing cost-effective bioprocesses and novel biosynthetic pathways, ZymoChem enables clients to reduce production costs and enhance their competitiveness in the market. Through its innovative approach, the company contributes to sustainable manufacturing practices and the advancement of a real-zero economy.

Aperiam Bio, founded in 2021 and based in Austin, Texas, specializes in the development of industrial and therapeutic proteins. The company collaborates with enzyme engineers and distributors to create stabilized, solubilized, and catalytically optimized proteins. Using advanced deep learning optimization and proprietary algorithms, Aperiam Bio identifies critical components of protein chemistry to discover novel gain-of-function mutations. This innovative approach enables the engineering of biological molecules for applications in agriculture and pharmaceuticals, allowing researchers to enhance the effectiveness and durability of proteins beyond their natural capabilities.

SURGE Therapeutics is dedicated to enhancing cancer patient survival through innovative approaches in immunotherapy. The company has developed a proprietary injectable biodegradable hydrogel designed for the prolonged and localized release of cancer immunotherapy following surgical tumor resection. By targeting the administration of treatment to specific areas at the optimal time, SURGE Therapeutics aims to improve the effectiveness of immunotherapy, allowing for both intravenous and intratumoral injections. This technology seeks to disrupt traditional cancer treatment paradigms and provide better outcomes for patients.

Andes develops an integrated microbial technology to help accelerate crop growth. Its technology is combined with artificial intelligence to develop its seeds while reducing input costs and environmental footprints and helps farmers to boost their agricultural output and income. Andes was founded in 2018 and is headquartered in Alameda, California.

Dimension Inx Corp. focuses on designing and developing three-dimensional (3D) printable materials and painted objects for research and commercial applications. The company specializes in creating regenerative microenvironments that aid the body in self-healing. Its biomaterials platform incorporates a complex interplay of material composition, microstructure, and microarchitecture to enhance biofunctionality. Dimension Inx offers a range of products, including Hyperelastic Bone for bone regeneration, 3D printable elastomers, bioactive ceramics, and solutions for soft tissue regeneration. Founded in 2016 and based in Chicago, Illinois, the company aims to provide innovative therapeutic products that restore tissue and organ function, potentially reducing the need for organ transplantation through advanced bio-fabrication processes.

Onc.AI, Inc. is a San Carlos, California-based company founded in 2020 that focuses on clinical oncology. It specializes in leveraging advanced technologies such as deep learning to enhance oncology diagnostics by providing insights derived from clinical oncology data, genomics, proteomics, and radiomics. The company's comprehensive approach aims to improve treatment outcomes by offering actionable insights that aid in the decision-making process for healthcare professionals in the oncology field.

Asimov, Inc. is a biotechnology company that specializes in the design and development of genetically engineered therapeutics. Established in 2017 and based in Cambridge, Massachusetts, Asimov focuses on creating tools for programming living cells to enhance the design and manufacturing processes of biologics and gene therapies. The company's platform integrates synthetic biology, computer-aided design, and machine learning, allowing for the engineering of genetic circuits. Asimov's multidisciplinary team employs machine-learning algorithms that connect large-scale datasets with biological models, facilitating advancements in molecular manufacturing and therapeutic applications. The company is dedicated to optimizing the production of protein biologics, viral vectors, and cell and gene therapies.

54gene is a healthcare company founded in 2019 by Dr. Abasi Ene-Obong, focused on advancing genomic research in Africa. Headquartered in San Francisco with an office in Lagos, Nigeria, the company aims to address the underrepresentation of African genetic data in pharmaceutical research, where only 2% of genetic material used is from African populations. By developing a pan-African biobank, 54gene seeks to identify new drug targets and create diagnostics and treatments for various diseases, including cancer, cardiovascular, and neurodegenerative diseases. Additionally, the company offers genetic testing and molecular diagnostics services to enhance understanding of the human genome and improve access to essential healthcare solutions.

Equii is a food technology company established in 2021 and located in San Ramon, California. Founded by Monica Bhatia, the company specializes in discovering and utilizing highly nutritious microbial proteins to enhance the fermentation of grains, resulting in high-protein grain flours. Equii's innovative approach transforms agricultural crops into nutritionally balanced products, catering to various eating occasions and providing consumers with access to healthier food options. Through its breakthrough technology, the company aims to deliver complete nutritional solutions, emphasizing the importance of protein-rich diets.

Tavros Therapeutics is a biotechnology company founded in 2019 and based in Durham, North Carolina. The company focuses on discovering and developing therapies for cancer, aiming to improve oncological treatment outcomes. Tavros Therapeutics is dedicated to identifying vulnerabilities within tumors, which allows for the targeted application of specific drugs in conjunction with optimal combinations. This approach is intended to enhance the effectiveness of cancer treatments and increase the potential for patient cures.

Canaery is focused on developing a neural interface that digitizes the sense of smell to analyze the scent fingerprints of objects. This innovative technology is designed to identify hazardous compounds at critical locations such as ports and inspection points. By utilizing this neurotech device, clients can detect not only the presence of dangerous substances but also gain insights into the nature and condition of the objects being inspected.

Faeth Therapeutics is a healthcare company dedicated to enhancing cancer treatment through a deep understanding of the relationship between dietary nutrients and tumor growth. By aligning specific diets with tumor genotypes and treatment regimens, Faeth aims to limit the energy and resources that tumors need to proliferate, thereby improving patient outcomes in cancer therapy. Founded by leading researchers and clinicians, the company seeks to translate significant discoveries from cancer research laboratories into effective clinical practices, focusing on evidence-based approaches to optimize treatment strategies for cancer patients.

Unravel Biosciences is a therapeutics company that originated from the Wyss Institute at Harvard University, focusing on developing new treatments for complex disorders. The company employs a unique approach by utilizing existing drugs to identify and clinically validate new therapeutic targets. Its AI-powered discovery engine integrates a comprehensive model of human health with rapid in vivo screening, allowing for the identification of drug targets at a significantly faster and more cost-effective rate than traditional methods. Unravel's platform has demonstrated its efficacy through discoveries that are currently being advanced into four clinical trials. Additionally, the company has built a robust portfolio of intellectual property and clinical samples, supported by partnerships established through its rareSHIFT™ services arm, positioning it for a rapid expansion of its therapeutics pipeline while maintaining profitability.

Zeta Surgical is a digital surgery company dedicated to enhancing the accuracy, safety, and accessibility of image-guided procedures. Its innovative navigation and robotics platform utilizes advanced computer vision and artificial intelligence to provide real-time image guidance at the point-of-care, opening new opportunities in emergency care and interventional medicine. The company specializes in developing surgical navigation tools that integrate 3D anatomical images, such as ultrasound and CT scans, directly within patients. This technology tracks and displays the position of surgical instruments alongside procedural blueprints, enabling surgeons to perform operations more effectively and safely. Founded by Harvard graduates and faculty, Zeta Surgical collaborates with leading hospitals and universities to advance its mission.

Terray Therapeutics is a biotechnology company based in Pasadena, California, founded in 2018. The company specializes in developing innovative treatments for complex human diseases by integrating experimentation and computation to enhance small molecule drug discovery. Terray's unique platform employs ultra-dense microarray technology alongside artificial intelligence and synthetic chemistry to generate extensive and precise chemical datasets. This allows for a rapid design-make-test-analyze cycle, facilitating efficient exploration of chemical space and mapping biochemical interactions between small molecules and disease causes. By utilizing automation and machine learning, Terray addresses significant therapeutic challenges, ultimately guiding the next cycles of drug design and experimentation.

Marigold Health operates a social network community platform designed to provide text-based group therapies for individuals facing mental health and substance use challenges. The platform facilitates anonymous support groups, allowing patients to engage with one another and receive guidance from coaches who have personal recovery experiences. By leveraging AI-augmented chat support, Marigold Health enhances the capacity of care teams while ensuring that patients receive personalized, stigma-free assistance. The company collaborates directly with treatment providers and managed care organizations within the Medicaid market to improve access to on-demand group therapies and foster a supportive community for recovery.

Faeth Therapeutics is a healthcare company dedicated to enhancing cancer treatment through a deep understanding of the relationship between dietary nutrients and tumor growth. By aligning specific diets with tumor genotypes and treatment regimens, Faeth aims to limit the energy and resources that tumors need to proliferate, thereby improving patient outcomes in cancer therapy. Founded by leading researchers and clinicians, the company seeks to translate significant discoveries from cancer research laboratories into effective clinical practices, focusing on evidence-based approaches to optimize treatment strategies for cancer patients.

Synteny.Ai Syntney decodes the signals of immune repertoires to help biotech research and pharma companies with disease discoveries.

Greeneye Technology is a company based in Tel-Aviv, Israel, founded in 2017, that focuses on precision agriculture through the use of artificial intelligence. The company has developed a proprietary selective spraying system that transforms conventional sprayers into smart machines capable of detecting weeds and applying herbicides precisely and in real-time. This innovative approach significantly reduces herbicide usage by as much as 90%, moving away from the traditional method of indiscriminate spraying. Greeneye's technology leverages machine learning and computer vision to automate field scouting and optimize herbicide application, providing farmers with valuable insights into their fields. The multidisciplinary team at Greeneye combines expertise in various fields, including agronomy and mechanical engineering, to deliver sustainable solutions that enhance agricultural practices globally.

ZymoChem, Inc. is a biotechnology company based in Emeryville, California, founded in 2013. It specializes in the development of eco-friendly chemicals and bioprocesses using engineered microbes to convert renewable feedstocks, such as sugars, into industrial chemicals. The company’s bio-manufacturing platform aims to produce bio-based materials while minimizing carbon emissions during production, thereby supporting a carbon-efficient economy. By establishing cost-effective bioprocesses and novel biosynthetic pathways, ZymoChem enables clients to reduce production costs and enhance their competitiveness in the market. Through its innovative approach, the company contributes to sustainable manufacturing practices and the advancement of a real-zero economy.

Elegen is a biotechnology company founded in 2017, focused on developing microfluidic technology to advance synthetic biology. Led by Dr. Matthew Hill, Elegen aims to revolutionize the field by engineering entire genomes and creating innovative DNA synthesizers. Their technology is designed to enhance the speed and efficiency of DNA sequence testing, thereby facilitating significant progress in biomedical research and healthcare applications. Through these efforts, Elegen seeks to contribute to the rapid development of solutions that address various challenges in the life sciences sector.

Parthenon Therapeutics is inventing a novel class of anti-cancer therapies that reprogram the tumor microenvironment (TME). The interplay between cancer cells and their surrounding microenvironment is relevant in drug development as manycancers use the TME to build barriers that shield immune system attack. One approach, PRTH-101, breaks these barriers to overcome recalcitrant cancers. Based on research, the company is designing a portfolio of drug candidates to treat the right patients at the right time.

54gene is a healthcare company founded in 2019 by Dr. Abasi Ene-Obong, focused on advancing genomic research in Africa. Headquartered in San Francisco with an office in Lagos, Nigeria, the company aims to address the underrepresentation of African genetic data in pharmaceutical research, where only 2% of genetic material used is from African populations. By developing a pan-African biobank, 54gene seeks to identify new drug targets and create diagnostics and treatments for various diseases, including cancer, cardiovascular, and neurodegenerative diseases. Additionally, the company offers genetic testing and molecular diagnostics services to enhance understanding of the human genome and improve access to essential healthcare solutions.

Debut Biotechnology, Inc. is a biotechnology company based in San Diego, California, established in 2019. It specializes in biomanufacturing solutions for high-value molecules, focusing on the development of specialty enzyme solutions and continuous manufacturing processes. The company offers a range of services, including biomanufacturing cartridges, fermentation, and the immobilization of cells and enzymes. Debut Biotechnology is dedicated to creating novel immobilization techniques for enzymes, achieving high success rates and providing immobilized enzymes for continuous manufacturing systems. Its innovative approach enables the production and modification of small and large molecules, catering primarily to the pharmaceutical and specialty chemical industries. By harnessing natural enzyme technologies, Debut aims to deliver sustainable and cost-effective ingredient solutions to its clients.

Andes develops an integrated microbial technology to help accelerate crop growth. Its technology is combined with artificial intelligence to develop its seeds while reducing input costs and environmental footprints and helps farmers to boost their agricultural output and income. Andes was founded in 2018 and is headquartered in Alameda, California.

Modulus Therapeutics is a company focused on developing immune cell therapies specifically aimed at treating solid tumors. By integrating genetic engineering with artificial intelligence and machine learning, Modulus Therapeutics creates optimized cell designs that enhance the efficacy of treatments for cancer and other serious diseases. This innovative approach allows for tailored therapies that improve patient outcomes in the fight against challenging medical conditions.

Xilis, Inc. is a biotechnology company based in Chapel Hill, North Carolina, founded in 2019. It specializes in developing advanced organoid technologies aimed at guiding precision therapy for cancer patients and enhancing drug discovery processes. The company's flagship platform, XilisµO, facilitates rapid diagnostics and personalized drug screening while providing scalable, patient-derived models for high-throughput drug discovery. This technology supports physicians and pharmaceutical companies in creating tailored treatments by enabling effective drug screening, ultimately contributing to more precise and cost-efficient cancer therapies.

PathAI, Inc. is a technology company that specializes in developing artificial intelligence solutions for pathology laboratories. Founded in 2016 and headquartered in Boston, Massachusetts, with an additional office in Austin, Texas, PathAI focuses on enhancing the accuracy and efficiency of cancer diagnosis and treatment. The company's platform employs machine and deep learning techniques to analyze large datasets, assisting pathologists in making rapid and precise diagnoses for patients. By addressing complex challenges in pathology, PathAI aims to facilitate personalized medicine and improve patient outcomes by identifying individuals who may benefit from innovative therapies.

Dyno Therapeutics Inc. is a biotechnology company based in Cambridge, Massachusetts, focused on developing innovative adeno-associated virus (AAV) vectors for gene therapy applications. Founded in 2018, the company employs an artificial intelligence-powered platform that integrates next-generation DNA synthesis, high-throughput sequencing, and machine learning. This advanced approach allows Dyno Therapeutics to design and optimize cell-targeting capsids, which are crucial for the effective and safe delivery of gene therapies. By leveraging its technology, the company aims to provide medical researchers with novel AAV vectors that enhance the efficacy of in vivo therapeutic solutions.

Rejuvenate Bio Inc is a biotechnology company based in Brookline, Massachusetts, founded in 2017. The company focuses on developing gene therapies aimed at increasing the health and lifespan of domesticated animals, particularly dogs. Its innovative therapies utilize new DNA instructions to provide anti-aging treatments and address specific diseases in pets. The foundation of Rejuvenate Bio's research is rooted in work from the Wyss Institute at Harvard Medical School, and the company has established a gene therapy pipeline that targets chronic age-related diseases. By leveraging clinically validated gene targets and effective delivery methods, Rejuvenate Bio aims for long-lasting and well-tolerated gene expression, ultimately enhancing the quality of life for both animals and potentially humans facing chronic health challenges.

SeQure Dx specializes in providing safety data related to CRISPR gene editing therapies, focusing on both on-target and off-target effects. The company develops genomics diagnostic technologies that facilitate target profiling for gene editing, supporting the discovery, clinical development, and diagnostic processes. Its core technologies are designed to identify potential off-target sites prior to the initiation of therapy, ensuring comprehensive confirmation of actual genetic edits. This capability empowers gene editing therapeutics developers, physicians, and patients by enhancing the safety and efficacy of gene editing treatments.

Theator Inc. is a surgical intelligence platform based in San Mateo, California, focused on enhancing surgeon performance through the use of artificial intelligence and computer vision. Founded in 2018, the company offers a personalized video platform called Minutes, which analyzes and houses video data from surgical procedures. This platform includes content management software and a visual operative report featuring analytics, allowing surgeons to review past surgeries for educational purposes. By extracting and annotating critical moments from real-world procedures, Theator enables surgeons to gain valuable insights into their performances and those of their peers, thereby promoting continuous improvement and expertise within the operating room. Theator collaborates with innovative surgeons and hospitals to foster a more transparent surgical environment.

Onc.AI, Inc. is a San Carlos, California-based company founded in 2020 that focuses on clinical oncology. It specializes in leveraging advanced technologies such as deep learning to enhance oncology diagnostics by providing insights derived from clinical oncology data, genomics, proteomics, and radiomics. The company's comprehensive approach aims to improve treatment outcomes by offering actionable insights that aid in the decision-making process for healthcare professionals in the oncology field.

Dimension Inx Corp. focuses on designing and developing three-dimensional (3D) printable materials and painted objects for research and commercial applications. The company specializes in creating regenerative microenvironments that aid the body in self-healing. Its biomaterials platform incorporates a complex interplay of material composition, microstructure, and microarchitecture to enhance biofunctionality. Dimension Inx offers a range of products, including Hyperelastic Bone for bone regeneration, 3D printable elastomers, bioactive ceramics, and solutions for soft tissue regeneration. Founded in 2016 and based in Chicago, Illinois, the company aims to provide innovative therapeutic products that restore tissue and organ function, potentially reducing the need for organ transplantation through advanced bio-fabrication processes.

Andes develops an integrated microbial technology to help accelerate crop growth. Its technology is combined with artificial intelligence to develop its seeds while reducing input costs and environmental footprints and helps farmers to boost their agricultural output and income. Andes was founded in 2018 and is headquartered in Alameda, California.

Abridge Inc. is a healthcare technology company founded in September 1999, focused on enhancing communication in medical settings through innovative tools. The company utilizes generative AI to automate the transcription and summarization of patient-clinician conversations, converting these interactions into structured clinical notes in real-time. This platform integrates seamlessly with Electronic Health Record (EHR) systems, significantly reducing the need for manual note-taking. By generating clear and understandable summaries, Abridge improves patient comprehension of medical discussions and ensures that relevant documentation is accurately recorded in patient files. Additionally, the company emphasizes data security and patient privacy, adhering to healthcare regulations while providing a customizable interface that caters to individual patient needs.

Rarebird is a coffee company that specializes in producing coffee products designed to enhance mental wellness. Utilizing Arabica coffee beans, the company incorporates a caffeine replacement compound known as paraxanthine, which is backed by research and aims to improve alertness while minimizing jitteriness and anxiety. Rarebird partners with third-party coffee sources to ensure that its beans are ethically and sustainably sourced, benefiting both producers and consumers. Through its innovative approach, Rarebird seeks to deliver coffee that not only tastes good but also supports better mental health outcomes.

Remedy Robotics is a developer of remote-controlled endovascular robots aimed at improving access to endovascular interventions worldwide. The company has created a device that automates the mechanical thrombectomy procedure, which is critical in treating stroke patients promptly. By enhancing the efficiency of this intervention, Remedy Robotics seeks to minimize the risk of severe disabilities following strokes, ultimately transforming patient care in the medical industry.

Andes develops an integrated microbial technology to help accelerate crop growth. Its technology is combined with artificial intelligence to develop its seeds while reducing input costs and environmental footprints and helps farmers to boost their agricultural output and income. Andes was founded in 2018 and is headquartered in Alameda, California.

Xilis, Inc. is a biotechnology company based in Chapel Hill, North Carolina, founded in 2019. It specializes in developing advanced organoid technologies aimed at guiding precision therapy for cancer patients and enhancing drug discovery processes. The company's flagship platform, XilisµO, facilitates rapid diagnostics and personalized drug screening while providing scalable, patient-derived models for high-throughput drug discovery. This technology supports physicians and pharmaceutical companies in creating tailored treatments by enabling effective drug screening, ultimately contributing to more precise and cost-efficient cancer therapies.

54gene is a healthcare company founded in 2019 by Dr. Abasi Ene-Obong, focused on advancing genomic research in Africa. Headquartered in San Francisco with an office in Lagos, Nigeria, the company aims to address the underrepresentation of African genetic data in pharmaceutical research, where only 2% of genetic material used is from African populations. By developing a pan-African biobank, 54gene seeks to identify new drug targets and create diagnostics and treatments for various diseases, including cancer, cardiovascular, and neurodegenerative diseases. Additionally, the company offers genetic testing and molecular diagnostics services to enhance understanding of the human genome and improve access to essential healthcare solutions.

Circularis Biotechnologies, Inc. is a biotechnology company focused on developing innovative methods to regulate gene expression, aiming to enhance the production yields of biotherapeutics. Founded in 2014 and based in Oakland, California, the company offers a range of products and services, including RACRE Variant Libraries, hCMV Variant Library, Protein expression with CMV promoters, and T7 Variant Library. Additionally, Circularis provides services such as RACRE Enhancement, RACRE Discovery, RACRE Technology Access Program, and Ribozyme Analysis of Cis-Regulatory Elements. Through its technology, Circularis Biotechnologies seeks to advance the capabilities of biotherapeutic production in the industry.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, that focuses on producing industrial chemicals through industrial biotechnology and green chemistry. Founded in 2016, Solugen develops a range of environmentally friendly products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. The company also offers ScavSol, a multivalent metal sequestrant for energy applications; ScaleSol, an alternative to phosphonates for scale control; and CorrSol, a corrosion and fouling control product. By utilizing fermentation and enzymatic technology to convert plant sugars into chemicals, Solugen aims to replace petroleum-based products with plant-derived alternatives. Its innovative solutions are designed to benefit various industries, including agriculture, cleaning, energy, and water, while also addressing critical issues such as clean water, sustainable materials, and healthier personal care products.

Character Therapeutics is a patient-driven therapeutics company that uses genomics, longitudinal clinical and imaging data, machine learning, and novel experimental approaches to identify the molecular drivers of disease progression and develop innovative targeted medicines. Its dedication to patients is reflected in the high standards set to ensure privacy, data security, ethics, scientific rigor, and a meaningful impact on patient health. To enable clinical genomic research, the company collaborates with patients, providers, payers, and scientists to create deeply phenotyped patient cohorts.

Circularis Biotechnologies, Inc. is a biotechnology company focused on developing innovative methods to regulate gene expression, aiming to enhance the production yields of biotherapeutics. Founded in 2014 and based in Oakland, California, the company offers a range of products and services, including RACRE Variant Libraries, hCMV Variant Library, Protein expression with CMV promoters, and T7 Variant Library. Additionally, Circularis provides services such as RACRE Enhancement, RACRE Discovery, RACRE Technology Access Program, and Ribozyme Analysis of Cis-Regulatory Elements. Through its technology, Circularis Biotechnologies seeks to advance the capabilities of biotherapeutic production in the industry.

Debut Biotechnology, Inc. is a biotechnology company based in San Diego, California, established in 2019. It specializes in biomanufacturing solutions for high-value molecules, focusing on the development of specialty enzyme solutions and continuous manufacturing processes. The company offers a range of services, including biomanufacturing cartridges, fermentation, and the immobilization of cells and enzymes. Debut Biotechnology is dedicated to creating novel immobilization techniques for enzymes, achieving high success rates and providing immobilized enzymes for continuous manufacturing systems. Its innovative approach enables the production and modification of small and large molecules, catering primarily to the pharmaceutical and specialty chemical industries. By harnessing natural enzyme technologies, Debut aims to deliver sustainable and cost-effective ingredient solutions to its clients.

Azitra Inc. is a clinical-stage medical dermatology company based in Farmington, Connecticut, focused on developing microbiome-based therapeutics for skin diseases. Established in 2014, Azitra leverages its proprietary platform, which includes a microbial library of bacterial strains, to discover and create novel treatments for adverse skin conditions. The company's technology, developed in collaboration with researchers at Yale University and the Jackson Laboratory, is centered around a specific strain of the natural commensal bacteria Staphylococcus epidermidis. Additionally, Azitra employs artificial intelligence and machine learning to enhance the screening and prediction of therapeutic characteristics within its microbial library. By utilizing engineered proteins and live biotherapeutic products for topical application, Azitra aims to advance precision dermatology.

54gene is a healthcare company founded in 2019 by Dr. Abasi Ene-Obong, focused on advancing genomic research in Africa. Headquartered in San Francisco with an office in Lagos, Nigeria, the company aims to address the underrepresentation of African genetic data in pharmaceutical research, where only 2% of genetic material used is from African populations. By developing a pan-African biobank, 54gene seeks to identify new drug targets and create diagnostics and treatments for various diseases, including cancer, cardiovascular, and neurodegenerative diseases. Additionally, the company offers genetic testing and molecular diagnostics services to enhance understanding of the human genome and improve access to essential healthcare solutions.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, that focuses on producing industrial chemicals through industrial biotechnology and green chemistry. Founded in 2016, Solugen develops a range of environmentally friendly products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. The company also offers ScavSol, a multivalent metal sequestrant for energy applications; ScaleSol, an alternative to phosphonates for scale control; and CorrSol, a corrosion and fouling control product. By utilizing fermentation and enzymatic technology to convert plant sugars into chemicals, Solugen aims to replace petroleum-based products with plant-derived alternatives. Its innovative solutions are designed to benefit various industries, including agriculture, cleaning, energy, and water, while also addressing critical issues such as clean water, sustainable materials, and healthier personal care products.

Theator Inc. is a surgical intelligence platform based in San Mateo, California, focused on enhancing surgeon performance through the use of artificial intelligence and computer vision. Founded in 2018, the company offers a personalized video platform called Minutes, which analyzes and houses video data from surgical procedures. This platform includes content management software and a visual operative report featuring analytics, allowing surgeons to review past surgeries for educational purposes. By extracting and annotating critical moments from real-world procedures, Theator enables surgeons to gain valuable insights into their performances and those of their peers, thereby promoting continuous improvement and expertise within the operating room. Theator collaborates with innovative surgeons and hospitals to foster a more transparent surgical environment.

Checkerspot, Inc. is a biotechnology company based in Berkeley, California, established in 2016. The company specializes in creating performance materials derived from microalgae, focusing on sustainable and high-performance applications. Checkerspot employs advanced techniques in molecular foundry, chemistry, material science, and fabrication technology to develop innovative products, including polyurethanes and textile finish materials. By leveraging the power of biotechnology, Checkerspot aims to expand the range of molecular building blocks available for various industrial applications, providing industries with access to a new generation of sustainable materials.

Terray Therapeutics is a biotechnology company based in Pasadena, California, founded in 2018. The company specializes in developing innovative treatments for complex human diseases by integrating experimentation and computation to enhance small molecule drug discovery. Terray's unique platform employs ultra-dense microarray technology alongside artificial intelligence and synthetic chemistry to generate extensive and precise chemical datasets. This allows for a rapid design-make-test-analyze cycle, facilitating efficient exploration of chemical space and mapping biochemical interactions between small molecules and disease causes. By utilizing automation and machine learning, Terray addresses significant therapeutic challenges, ultimately guiding the next cycles of drug design and experimentation.

Hi Fidelity Genetics LLC, based in Durham, North Carolina, specializes in developing hardware and software for plant-breeding applications. The company creates tools that measure and predict plant traits, which are vital for ensuring a sufficient food supply amid a growing global population and changing climate conditions. By democratizing seed breeding and enhancing agricultural productivity, Hi Fidelity Genetics aims to improve the profitability of producers while offering genetics modification services that yield similar results to traditional methods.

Abridge Inc. is a healthcare technology company founded in September 1999, focused on enhancing communication in medical settings through innovative tools. The company utilizes generative AI to automate the transcription and summarization of patient-clinician conversations, converting these interactions into structured clinical notes in real-time. This platform integrates seamlessly with Electronic Health Record (EHR) systems, significantly reducing the need for manual note-taking. By generating clear and understandable summaries, Abridge improves patient comprehension of medical discussions and ensures that relevant documentation is accurately recorded in patient files. Additionally, the company emphasizes data security and patient privacy, adhering to healthcare regulations while providing a customizable interface that caters to individual patient needs.

Dyno Therapeutics Inc. is a biotechnology company based in Cambridge, Massachusetts, focused on developing innovative adeno-associated virus (AAV) vectors for gene therapy applications. Founded in 2018, the company employs an artificial intelligence-powered platform that integrates next-generation DNA synthesis, high-throughput sequencing, and machine learning. This advanced approach allows Dyno Therapeutics to design and optimize cell-targeting capsids, which are crucial for the effective and safe delivery of gene therapies. By leveraging its technology, the company aims to provide medical researchers with novel AAV vectors that enhance the efficacy of in vivo therapeutic solutions.

Visla Labs Inc. is a San Francisco-based startup focused on developing an artificial intelligence platform tailored for the radiology and healthcare sectors. Incorporated in 2018, the company is dedicated to advancing healthcare technology, aiming to create innovative solutions that enhance diagnostic processes and patient care. With venture capital backing, Visla Labs is positioned for significant growth as it approaches a critical milestone in its development.

Tierra Biosciences is a synthetic biology company focused on advancing the discovery of bioengineered products through innovative technologies. Founded in 2015 and headquartered in San Francisco, California, the company specializes in cell-free technologies that facilitate the production of complex molecules that traditional laboratory cells find challenging to generate. Its Next Generation Expression platform integrates automation, computation, and high-throughput cell-free expression to enable rapid, experimentally validated data collection, surpassing the limitations of simulation-based methods. By combining cell-free protein production with artificial intelligence, Tierra Biosciences aims to streamline protein manufacturing, making it as accessible as e-commerce. The company was formerly known as Synvitrobio, Inc., before rebranding in September 2018.

Checkerspot, Inc. is a biotechnology company based in Berkeley, California, established in 2016. The company specializes in creating performance materials derived from microalgae, focusing on sustainable and high-performance applications. Checkerspot employs advanced techniques in molecular foundry, chemistry, material science, and fabrication technology to develop innovative products, including polyurethanes and textile finish materials. By leveraging the power of biotechnology, Checkerspot aims to expand the range of molecular building blocks available for various industrial applications, providing industries with access to a new generation of sustainable materials.

Rejuvenate Bio Inc is a biotechnology company based in Brookline, Massachusetts, founded in 2017. The company focuses on developing gene therapies aimed at increasing the health and lifespan of domesticated animals, particularly dogs. Its innovative therapies utilize new DNA instructions to provide anti-aging treatments and address specific diseases in pets. The foundation of Rejuvenate Bio's research is rooted in work from the Wyss Institute at Harvard Medical School, and the company has established a gene therapy pipeline that targets chronic age-related diseases. By leveraging clinically validated gene targets and effective delivery methods, Rejuvenate Bio aims for long-lasting and well-tolerated gene expression, ultimately enhancing the quality of life for both animals and potentially humans facing chronic health challenges.

Sepsis Scout is a developer of a wearable patch aimed at predicting the onset of sepsis in high-risk patients in a home care setting. The device utilizes proprietary deep learning technology to enhance the accuracy of sepsis predictions compared to current standards of care. By enabling patients to monitor their health more effectively, Sepsis Scout's solution helps manage chronic illnesses and reduces the need for hospital visits, alleviating the fear and uncertainty associated with serious health conditions.

Azitra Inc. is a clinical-stage medical dermatology company based in Farmington, Connecticut, focused on developing microbiome-based therapeutics for skin diseases. Established in 2014, Azitra leverages its proprietary platform, which includes a microbial library of bacterial strains, to discover and create novel treatments for adverse skin conditions. The company's technology, developed in collaboration with researchers at Yale University and the Jackson Laboratory, is centered around a specific strain of the natural commensal bacteria Staphylococcus epidermidis. Additionally, Azitra employs artificial intelligence and machine learning to enhance the screening and prediction of therapeutic characteristics within its microbial library. By utilizing engineered proteins and live biotherapeutic products for topical application, Azitra aims to advance precision dermatology.

Elemental Machines, Inc., founded in 2014 and based in Cambridge, Massachusetts, specializes in providing a smart lab platform designed to enhance laboratory operations in science-based industries. The company's innovative technology continuously monitors equipment and environmental variables, delivering data-driven insights that foster improved research, development, and manufacturing outcomes. By utilizing intelligent sensors, the platform visualizes the entire testing environment and issues alerts for any anomalous results, thereby ensuring experimental reproducibility. This capability allows clients to refine and accelerate their work across all phases of product innovation, ultimately leading to greater clarity, transparency, and consistency in laboratory processes.

Elemental Machines, Inc., founded in 2014 and based in Cambridge, Massachusetts, specializes in providing a smart lab platform designed to enhance laboratory operations in science-based industries. The company's innovative technology continuously monitors equipment and environmental variables, delivering data-driven insights that foster improved research, development, and manufacturing outcomes. By utilizing intelligent sensors, the platform visualizes the entire testing environment and issues alerts for any anomalous results, thereby ensuring experimental reproducibility. This capability allows clients to refine and accelerate their work across all phases of product innovation, ultimately leading to greater clarity, transparency, and consistency in laboratory processes.

Hi Fidelity Genetics LLC, based in Durham, North Carolina, specializes in developing hardware and software for plant-breeding applications. The company creates tools that measure and predict plant traits, which are vital for ensuring a sufficient food supply amid a growing global population and changing climate conditions. By democratizing seed breeding and enhancing agricultural productivity, Hi Fidelity Genetics aims to improve the profitability of producers while offering genetics modification services that yield similar results to traditional methods.

PathAI, Inc. is a technology company that specializes in developing artificial intelligence solutions for pathology laboratories. Founded in 2016 and headquartered in Boston, Massachusetts, with an additional office in Austin, Texas, PathAI focuses on enhancing the accuracy and efficiency of cancer diagnosis and treatment. The company's platform employs machine and deep learning techniques to analyze large datasets, assisting pathologists in making rapid and precise diagnoses for patients. By addressing complex challenges in pathology, PathAI aims to facilitate personalized medicine and improve patient outcomes by identifying individuals who may benefit from innovative therapies.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, that focuses on producing industrial chemicals through industrial biotechnology and green chemistry. Founded in 2016, Solugen develops a range of environmentally friendly products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. The company also offers ScavSol, a multivalent metal sequestrant for energy applications; ScaleSol, an alternative to phosphonates for scale control; and CorrSol, a corrosion and fouling control product. By utilizing fermentation and enzymatic technology to convert plant sugars into chemicals, Solugen aims to replace petroleum-based products with plant-derived alternatives. Its innovative solutions are designed to benefit various industries, including agriculture, cleaning, energy, and water, while also addressing critical issues such as clean water, sustainable materials, and healthier personal care products.