Circuit Clinical
Seed Round in 2020
Circuit Clinical is an integrated research organization that facilitates participation in clinical research for patients and healthcare providers. Founded in 2015, it emerged from the experiences of a physician who recognized the importance of trust in the clinical research process. Circuit Clinical focuses on enhancing physician and participant engagement, leveraging HIPAA and FDA-compliant Electronic Medical Record (EMR) reviews to identify motivated participants. The organization provides a suite of technology products designed to improve the clinical research experience for both participants and physicians. By connecting a network of over one million patients with community physicians and research sponsors, Circuit Clinical aims to improve site quality and patient safety, making clinical research more accessible and navigable for all involved.
TriSalus Life Sciences
Series C in 2015
TriSalus Life Sciences, based in Westminster, Colorado, focuses on developing innovative drug delivery technologies and immune-oncology therapeutics aimed at improving treatment outcomes for challenging cancers, particularly liver and pancreatic cancer. Founded in 2009, the company specializes in precision infusion systems designed for interventional radiology. Its product offerings include Pressure Enabled Drug Delivery (PEDD) systems, which utilize a unique expandable tip catheter to deliver embolic agents while minimizing damage to healthy tissues. The Surefire infusion systems, including various models for lobar, segmental, and super-selective infusions, aim to enhance tumor uptake through controlled pressure and blood flow management. Additionally, TriSalus is advancing an investigational therapy, nelitolimod, which has shown promise in enhancing immune response against liver tumors. The company continues to innovate with devices like the TriNav, which employs SmartValve technology to optimize drug delivery.
Bottlenose
Series B in 2015
Bottlenose, Inc. specializes in business intelligence software designed to help enterprises identify threats and opportunities through the analysis of stream data. Its flagship product, Nerve Center, is a SaaS platform that allows analysts and strategists to monitor real-time internal and external factors impacting their businesses. The platform excels in detecting patterns and trends, providing insights on brand reputation, consumer behavior, competitive intelligence, crisis management, and market research. By automating machine learning and predictive analytics, Bottlenose enables clients to focus on deriving actionable insights rather than data management. Founded in 2010, Bottlenose is headquartered in Sherman Oaks, California, with additional offices in San Francisco and New York City, serving a diverse clientele, including Fortune 100 companies.
Coherus Biosciences
Series C in 2014
Coherus Biosciences is a biopharmaceutical company that specializes in the development, manufacture, and commercialization of biologic therapeutics, with a strong emphasis on oncology and inflammatory diseases. The company is actively engaged in research and development, focusing on process science, analytical characterization, and protein production. Coherus's portfolio includes FDA-approved products such as UDENYCA, a biosimilar of Neulasta, and it plans to launch YUSIMRY, a biosimilar of Humira, in the United States. Additionally, the company is advancing a pipeline of biosimilar candidates across areas such as immunology and ophthalmology, as well as anti-tumor necrosis factor treatments. With a commitment to building an immuno-oncology franchise, Coherus aims to leverage its diversified portfolio to generate revenue and enhance patient access to biologic therapies.
Wildflower Health
Series A in 2013
Wildflower Health, Inc. is a health engagement platform based in San Francisco, California, that provides smartphone-based health programs aimed at connecting healthcare payers with families across the United States. Founded in 2012, the company offers a maternity program called Due Date Plus, which addresses engagement challenges by assisting women in early pregnancy and facilitating connections with care managers. Additionally, Wildflower Health provides GROW, a family health program that focuses on mothers and encompasses pediatric and family health. Its platform delivers personalized health milestones based on age and gender, along with resources such as on-device messaging, appointment reminders, health risk assessments, and provider referrals. By utilizing user-centered design and technology, Wildflower Health aims to empower families to make informed healthcare decisions and support their individual health needs over time.
FitBionic
Venture Round in 2013
FitBionic Inc. is a Boulder, Colorado-based company that specializes in designing and manufacturing prosthetic walking feet for individuals suffering from neuropathy, vascular disease, scarring, and fragile skin issues. Established in 2006 and previously known as Tensegrity Prosthetics Inc., FitBionic aims to provide whole-person care for amputees, promoting healthy and active lifestyles. The company's flagship product, the FitBionic Foot, has been shown to enhance walking efficiency compared to traditional carbon fiber prosthetics, while also potentially reducing pain and fall risks. FitBionic's research and development efforts have been supported by the National Institutes of Health, highlighting the company's commitment to creating high-quality and affordable prosthetic solutions that cater specifically to the needs of diabetics and other users. Through partnerships with centers of excellence, FitBionic seeks to ensure that its innovative products deliver comfort and functionality comparable to biological limbs.
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