Knight Therapeutics

Knight Therapeutics Inc. is a specialty pharmaceutical company based in Montreal, Canada, engaged in the development, acquisition, in-licensing, out-licensing, marketing, and distribution of innovative prescription pharmaceuticals, consumer health products, and medical devices. The company offers a range of commercialized products, including Movantik for opioid-induced constipation, Mytesi for noninfectious diarrhea in adults with HIV or AIDS, NERLYNX for HER2-positive breast cancer, and Trelstar for prostate cancer. Additionally, Knight Therapeutics is involved in the development of treatments for conditions such as opioid addiction, chronic pain, diabetes-related eye diseases, and neurological disorders. Their product pipeline includes various therapies targeting acute migraine, HPV-associated cancers, and osteoarthritis-related pain, among others. Founded in 2013, Knight Therapeutics continues to expand its portfolio and invest in innovative life sciences solutions both in Canada and internationally.

Jonathan Goodman

Founder, Chairman of the Board and Senior Administrator

6 past transactions

Paladin Pharma

Acquisition in 2025
Paladin Pharma is a Canadian specialty pharmaceutical company that focuses on developing, acquiring, licensing, and commercializing innovative medicines for the Canadian market. It operates as an indirect subsidiary of Endo International plc, delivering quality products to patients through excellence in development, manufacturing, and commercialization.

Grupo Biotoscana

Acquisition in 2019
Grupo Biotoscana is a biopharmaceutical company based in Latin America, formed through the merger of two established specialty pharmaceutical firms with over 25 years of experience each. The company focuses on developing, manufacturing, and selling pharmaceutical products aimed at addressing unmet medical needs, particularly in oncology, hematology, severe infectious diseases, and rare genetic disorders. Grupo Biotoscana is recognized for its expertise in complex therapeutic areas and maintains long-term collaborations with prominent global pharmaceutical companies, enhancing its ability to deliver specialized treatments and innovative solutions in the healthcare sector.

Synergy CHC

Post in 2017
Synergy CHC is a consumer health care and beauty company specializing in marketing and distributing branded products across North America. Its portfolio includes FOCUSfactor (brain-health supplements), Flat Tummy (weight management products), Hand MD (anti-aging skincare for hands), Neuragen (topical pain relief), and Sneaky Vaunt (backless bras). Products are sold directly to wholesalers, online, and through retail channels.

INTEGA Skin Sciences

Debt Financing in 2016
INTEGA Skin Sciences is a dermatology company focused on the development, manufacturing, and marketing of science-based skin care products. The company specializes in producing and distributing a range of dermatological creams and lotions, catering to both Canadian and American markets. By emphasizing quality and scientific research, INTEGA Skin Sciences aims to meet the diverse needs of consumers seeking effective skin care solutions.

Advaxis

Post in 2015
Advaxis, Inc. is a clinical-stage biotechnology company based in Princeton, New Jersey, specializing in the development of immunotherapies for cancer and infectious diseases. The company utilizes a unique platform technology involving live, attenuated bacteria engineered to deliver antigen/adjuvant fusion proteins, effectively redirecting immune responses to target cancer cells. Advaxis is advancing several product candidates, including axalimogene filolisbac for HPV-related cancers, currently undergoing Phase II clinical trials for head and neck cancer. Additionally, it is developing ADXS-PSA for prostate cancer and ADXS-NEO, which personalizes treatment by using whole-exome sequencing to identify tumor neoantigens. Other projects include ADXS-HOT, aimed at generating robust anti-cancer immunity, and ADXS-HER2, designed to target HER2-expressing solid tumors. The company has established collaborations and licensing agreements with various organizations, enhancing its research and development efforts.

Profound Medical

Venture Round in 2015
Profound Medical Corp. is a medical technology company based in Mississauga, Canada, specializing in the development of innovative, incision-free therapeutic systems for the image-guided ablation of diseased tissue. The company’s flagship product, the TULSA-PRO system, integrates real-time magnetic resonance imaging with robotically driven thermal ultrasound to precisely ablate prostate tissue. Additionally, Profound Medical offers the Sonalleve platform, which is designed for treating uterine fibroids and managing palliative pain associated with bone metastases. By leveraging existing MRI infrastructure, the company aims to provide customizable and non-invasive treatment options that address the unmet needs of patients and clinicians. Profound Medical is committed to enhancing the standard of care through its advanced technologies and has established a co-development agreement with GE Healthcare to broaden access to its TULSA-PRO system.
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