Daxor Corporation is a medical device and biotechnology company based in New York, founded in 1970. It specializes in blood volume measurement, offering the BVA-100 Blood Volume Analyzer, the first FDA-approved instrument for the rapid and direct measurement of a patient's true blood volume. This device is utilized in diagnosing and managing various medical conditions, including congestive heart failure, critical care medicine, hypertension, and anemia. In addition to its core product, Daxor provides cryobanking services such as semen banking and blood storage, along with andrology and general laboratory testing services. The company also collaborates with the Uniformed Services University of the Health Sciences to research the effectiveness of its diagnostic tests in traumatic injury contexts. Daxor was previously known as Idant Corporation before rebranding in May 1973.
Daxor Corporation is a medical device and biotechnology company based in New York, founded in 1970. It specializes in blood volume measurement, offering the BVA-100 Blood Volume Analyzer, the first FDA-approved instrument for the rapid and direct measurement of a patient's true blood volume. This device is utilized in diagnosing and managing various medical conditions, including congestive heart failure, critical care medicine, hypertension, and anemia. In addition to its core product, Daxor provides cryobanking services such as semen banking and blood storage, along with andrology and general laboratory testing services. The company also collaborates with the Uniformed Services University of the Health Sciences to research the effectiveness of its diagnostic tests in traumatic injury contexts. Daxor was previously known as Idant Corporation before rebranding in May 1973.
Yaya Scientific
Grant in 2021 
Yaya Scientific is a platform that provides biomedical solutions.
Eden Concepts
Grant in 2021 
Eden Concepts is a precision agriculture technology development and consulting firm based in Lenoir City, Tennessee, established in 2018. The company focuses on enhancing farm productivity for small-scale farmers by developing innovative agricultural technologies tailored for vegetables and specialty crops. Its precision systems are designed to prepare and plant germinated seeds, replacing the traditional methods of growing and transplanting seedlings. By improving soil health and offering greater flexibility in crop selection, Eden Concepts aims to streamline farming operations, helping farmers reduce labor costs and energy consumption.
Immuno Technologies
Grant in 2021 
Immuno Technologies is a US-based company that focuses on applied research for infectious diseases.
RxBio is a biotechnology company based in Johnson City, Tennessee, focused on developing innovative therapies to protect against lethal whole-body radiation and mitigate gastrointestinal damage caused by radiation, chemotherapy, and various toxins. Since its incorporation in 2010, RxBio has specialized in creating novel drugs aimed at addressing acute radiation syndrome, with particular emphasis on gastrointestinal protection. The company also explores cancer agents and treatments that inhibit plaque build-up in blood vessels, contributing to the medical community's ability to manage chronic conditions effectively.
Tetrahive is a STEM-focused company with expertise in software development, data analysis, and computational modeling & simulation.
Healing Innovations
Grant in 2021 
Healing Innovations, Inc. is a medical technology company established in 2018 and based in Nashville, Tennessee. The company specializes in manufacturing advanced rehabilitation equipment aimed at supporting individuals recovering from spinal cord injuries, strokes, traumatic brain injuries, and conditions such as cerebral palsy, multiple sclerosis, and muscular dystrophy. To enhance care within the rehabilitation continuum, Healing Innovations focuses on the development and commercialization of market-leading robotic technologies. These innovations aim to improve health, mobility, and independence for users, while also enabling medical professionals and managed care organizations to enhance efficiency and quality of care at a reasonable cost.
LiBAMA Power
Grant in 2021 
LiBAMA Power, established in 2017 and based in Cookeville, Tennessee, specializes in the design, manufacture, and marketing of advanced metal anodes (AMAs) for next-generation lithium-metal batteries. The company's core business involves developing and commercializing cutting-edge lithium metal battery technology, aiming to enhance energy density without disrupting existing manufacturing processes. This innovation caters to various industries, including consumer electronics, electric vehicles, and aerospace, offering unprecedented mobile power solutions.
Eonix develops a semi-autonomous materials research and development platform called ATLAS that streamlines the design of lithium-ion battery materials. The system aims to cut development time and costs by accelerating discovery of compounds and electrolyte formulations that enable higher energy density and voltage operation. The company targets applications across electric vehicles, grid storage, and defense-related energy storage, seeking to address market barriers and support the adoption of clean tech solutions. Through rapid material design, Eonix seeks to deliver electrolyte solutions that enhance performance for next-generation energy storage technologies.
Qardian Labs
Grant in 2021 
Qardian Labs provides AI-based decision-making software for healthcare, focusing on cardiac risk assessment. The platform employs deep learning and neural networks to analyze structured patient metrics such as cholesterol, blood pressure, and echocardiogram results to identify relationships that signal heart disease. It enables clinicians, sports physicians, and military personnel to conduct data-informed cardiac risk evaluations within routine workflows, using patients' reports and health outputs to support clinical decision-making.
NellOne Therapeutics
Grant in 2021 
NellOne Therapeutics, Inc. is a regenerative medicine company based in Oak Ridge, Tennessee, focused on developing and commercializing protein therapeutics aimed at restoring cardiac muscle mass and function in patients recovering from myocardial infarction and congestive heart failure. The company was established in 2007 as a spin-out from the U.S. Department of Energy's Oak Ridge National Laboratory, where research led by Dr. Cymbeline Culiat identified the Nell1 gene's role in the formation of essential mammalian tissues and organs. NellOne is dedicated to translating these scientific discoveries into clinical applications, specifically by leveraging Nell1 protein therapeutics to rebuild cardiac muscle and improve patient outcomes following heart-related conditions.
American Nanotechnologies
Grant in 2021 
American Nanotechnologies specializes in developing innovative systems for large-scale purification of high-value dielectric materials.
Phelps 2020 is a scientific & technological firm offering technological, algorithms, data & hardware services.
Active Energy Systems
Grant in 2021 
Active Energy Systems is leveraging its scientific expertise to develop and market an improved form of ice thermal energy storage. The company's headquarters are in Knoxville, Tennessee.
Very Real Help
Grant in 2021 
Innerworld is a developer of a psychological platform that utilizes virtual reality technology to address mental health disorders. The platform offers a unique service called Help Club™, which provides unlimited group sessions aimed at helping users set and achieve their wellness goals in an anonymous and stigma-free environment. Through its proprietary technique, Cognitive Behavioral Immersion™, Innerworld transports users to immersive worlds designed specifically for wellness, enabling them to learn essential skills for emotional regulation. This innovative approach aims to make mental health support accessible, affordable, and effective for individuals seeking to enhance their well-being.
Couture Technologies
Grant in 2021 
Couture Technologies is a software development firm that specializes in AI, ML, and 3D simulation to power virtual fitting and try-on capabilities for e-commerce. Founded in 2019 and headquartered in Gallatin, Tennessee, the company builds tools that show how apparel items will look and fit on a customer's body, enabling retailers to offer an interactive online shopping experience.
Addiguru specializes in providing intelligent monitoring solutions for Additive Manufacturing processes. Its technology is machine- and material-independent, allowing seamless integration into existing and new AM equipment.
IDBiologics is a biotechnology company that develops human monoclonal antibodies for the prevention, treatment, and cure of infectious diseases. Its proprietary antibody platform enables rapid discovery and optimization of broad, potent therapeutic molecules, delivering extensive capability to isolate antibodies for varied infectious disease targets. Lead candidate molecules across diverse targets are advancing toward development, with the goal of expanding options to treat, prevent, and cure infectious diseases.
Branch Technology
Grant in 2021 
Founded in 2014, Branch Technology specializes in developing and implementing Cellular Fabrication technology for construction. Using proprietary algorithms and 3D printing, the company creates complex geometries without support materials or controlled environments, enabling cost-effective designs, improved material strength, reduced energy use, and job site efficiencies.
Muzology makes music learning fun, engaging, and effective.
HeroWear develops wearable exoskeleton technology for workers in physically demanding jobs, aiming to reduce fatigue and musculoskeletal strain. Its Apex back-assist exosuit is designed from the ground up to fit men and women, featuring dual-mode technology that turns back support on or off for use in a range of work scenarios. The textile-based design is modular, offering more than 50 configurations to tailor fit and level of assistance. The systems focus on lift assistance to aid in strenuous tasks and daily chores, with the goal of improving safety, health, and productivity by reducing body pain and related ailments while wearing a comfortable garment.
Assured Bio Labs
Grant in 2021 
Assured Bio Labs is a laboratory for testing mold, bacteria, and coliforms using traditional microscopic and DNA-based analysis.
Preteckt provides a cloud-based platform that analyzes real-time automotive sensor data to predict maintenance needs and prescribe repairs for connected and autonomous vehicles and fleets. The platform leverages proprietary AI, deep learning, and machine learning to handle automotive data and deliver vehicle prognostics-as-a-service to fleets, municipalities, telematics providers, and OEMs. Its architecture supports rapid real-time processing and scalable deployment with existing vehicles and fleets, aiming to reduce maintenance costs, improve technician efficiency, and minimize downtime by identifying issues early and recommending appropriate repairs.
Ultrasonic Technology Solutions
Grant in 2021 
Ultrasonic Technology Solutions specializes in the development of advanced ultrasonic dryers designed for industrial and commercial applications. These dryers are engineered to operate at twice the speed and achieve three to five times the efficiency of traditional heat-based drying systems. By offering significant benefits such as reduced energy costs, enhanced sustainability, and improved worker safety, Ultrasonic Technology Solutions provides clients with a modern alternative to conventional drying methods. The company's innovative approach aims to transform the drying process, making it more efficient and environmentally friendly.
Virtuoso Surgical
Grant in 2021 
Virtuoso Surgical develops endoscopic robotic tools for minimally invasive surgery. Its Virtuoso robotic surgery system enables surgeons to overcome limitations of traditional endoscopes, with needle-sized robotic arms that reach difficult-to-access areas. The company focuses on simplifying endoscopic procedures and provides a range of tools to help surgeons perform operations more effectively and potentially improve patient outcomes.
SkyNano is a science-based technology company dedicated to commercializing solutions that address carbon pollution. The firm develops innovative carbon materials that utilize carbon emissions as a feedstock for manufacturing functional materials. Leveraging proprietary electrochemistry, SkyNano offers a low-cost, scalable, and sustainable approach to producing advanced carbon materials suitable for various applications. By transforming carbon emissions into valuable products, the company aims to help clients mitigate the adverse effects of climate change.
Lux Semiconductors
Grant in 2021 
Lux Semiconductors develops crystalline thin-film semiconductors used in flexible integrated circuits and designs metal-core substrates intended to replace traditional organic and glass cores in advanced semiconductor packages. The company's patented platform improves heat dissipation, power delivery, electromagnetic shielding, structural stability, and signal integrity, enabling manufacturers across data-center processors, AI accelerators, aerospace and defense electronics, automotive systems, battery management, and medical devices to overcome performance bottlenecks.
Winter Innovations
Grant in 2021 
Winter Innovations is a Knoxville, Tennessee-based startup founded in 2018 that focuses on developing medical devices aimed at enhancing patient outcomes in orthopedic care. The company is in the process of launching EasyWhip, a patent-pending suturing needle specifically designed for orthopedic ligament and tendon reconstruction surgery. This innovative device seeks to simplify and standardize the whip stitching technique, offering advantages such as ease of use, speed, stability, and versatility. Through these improvements, Winter Innovations aims to help surgeons perform orthopedic reconstruction procedures more efficiently and consistently.
Gridfruit is a provider of a data-driven intelligence to food operations.
Its artificial intelligence-based learning platform utilizes existing food data to reduce energy and maintenance costs for food businesses.
The companty was established in Pittsburgh, Pennsylvania in 2018.
Stony Creek Colors
Grant in 2021 
Stony Creek Colors, Inc. is a manufacturer of bio-based colorants specifically designed for the textile industry. Founded in 2012 by Sarah Bellos and based in Springfield, Tennessee, the company collaborates with small farmers in the Southeastern United States to produce plant-based dyes, including indigo. Stony Creek Colors aims to provide clean and safe alternatives to hazardous chemicals traditionally used in dyeing processes, supporting environmentally conscious practices within the textile and fashion industries. Through its innovative technology, the company enables mills and brands to offer premium products that prioritize sustainability and health.
Mobius develops environmental solutions that convert industrial organic waste streams into polymers and materials. The company uses lignin, a waste byproduct from the paper and biofuel industries, to produce a natural, biodegradable polymer. This bio-based polymer is intended for applications in horticulture, agriculture, and food service packaging, among others, enabling customers in forestry, paper, biofuel, and biorefining sectors to replace conventional plastics with environmentally friendly alternatives. The approach aims to reduce waste generation and support circular economy goals by turning waste streams from agriculture, forestry, and related industries into new materials and chemicals.
Mobius develops environmental solutions that convert industrial organic waste streams into polymers and materials. The company uses lignin, a waste byproduct from the paper and biofuel industries, to produce a natural, biodegradable polymer. This bio-based polymer is intended for applications in horticulture, agriculture, and food service packaging, among others, enabling customers in forestry, paper, biofuel, and biorefining sectors to replace conventional plastics with environmentally friendly alternatives. The approach aims to reduce waste generation and support circular economy goals by turning waste streams from agriculture, forestry, and related industries into new materials and chemicals.