Lionheart Ventures

Lionheart Ventures is a global, seed-stage venture capital firm focused on mitigating civilizational risk. We do this by supporting the wise development of transformative technologies. Our main areas of investment focus are transformative artificial intelligence and frontier mental health technologies. Leading academics estimate a 1-in-6 chance of human extinction by the year 2100, largely driven by risks from emerging technologies. And now, with the exponential growth of AI, predictions are getting worse. Our startups are part of the solution. We invest in exceptional, ethical founders who are developing transformative technologies that have the potential to impact humanity on a meaningful scale, while generating attractive returns for our LPs.

Shelby Clark

Partner, Mental Health

Carlos López Enríquez

VP of Finance

Milan Griffes

Principal

David Langer

Founding Partner

26 past transactions

Homecoming

Seed Round in 2022
Homecoming is a provider of patient engagement tools for psychedelic therapy.

WellSet

Seed Round in 2022
WellSet is a digital mental health studio streaming classes in holistic practices. They can attend live classes every day and access a huge on-demand library whenever they want. They provide stretching, self-hypnosis, functional medicine, breathwork, eft tapping, guided journaling, meditation, and more.

Mindstate Design Labs

Seed Round in 2022
Mindstate Design Labs is a clinical-stage biotechnology company developing the next generation of psychedelic-inspired therapeutics for intractable mental health conditions. The company maps the biological basis of the varieties of psychedelic experiences and uses that map to design psychoactive effects to be applied in medically supervised settings to heal the root causes of mental health disorders.

Breathwrk

Funding Round in 2022
The Breathwrk app offers easy to follow and highly effective guided breathing exercises that alleviate anxiety, promote sleep, increase energy, improve mood, help with athletic performance, and more!

Progressive Therapeutics Inc

Seed Round in 2021
Progressive Therapeutics is a life sciences company developing novel psychoactive and psychedelic therapeutics.

wavepaths

Seed Round in 2021
Wavepaths creates accessible tools in psychedelic therapy intended for inner exploration and personal transformation. The company specializes in the fields of information technology, healthcare, and personal health. It was founded in 2018 and headquartered in London, England.

Journey Colab

Venture Round in 2021
Journey Colab pursuing FDA approval of psychedelic therapies to heal individual mental health and strengthen communities. Their first compound in development is mescaline. It was founded in 2020 and is based in San Francisco, California.

Journey Clinical

Seed Round in 2021
Journey Clinical is a platform that provides services to member psychotherapy practices that are independently owned and operated, and in no way owns, directs, or controls the mental healthcare clinicians providing care.

Formo

Series A in 2021
Formo is Europe’s first cellular agriculture company developing animal-free dairy products using real, nature-identical milk proteins derived from precision fermentation.

Wild Earth

Series A in 2021
Wild Earth is a technology startup that specializes in developing protein pet foods. It is dedicated to reinventing pet food with science to offer healthier foods for pets that are better for the environment and more humane than conventional products. The company was founded in 2017 and is headquartered in Berkeley, California.

Tactogen

Pre Seed Round in 2021
Tactogen is a biopharma startup that develops empathogen medicines. The startup company offers drug discovery methods, novel molecules, and pharmaceutical preparations that focus on one goal: enabling safer take-home prescription empathogens. It is headquartered in Palo Alto, California in 2020 by Ph.D. neuroscientist Matthew Baggott and deeptech serial entrepreneur Luke Pustejovsky.

Bexson Biomedical

Series A in 2021
Bexson Biomedical is developing a unique formulation of ketamine for chronic and acute pain disorders.

Dendra Systems

Series A in 2020
Dendra's vision is to empower humanity to restore the balance of our natural world. Our mission is to create the tools needed to power scalable ecosystem restoration.

Fathom Computing

Seed Round in 2020
Fathom Radiant was created on the premise of applying first-principles thinking to create technology capable of enabling artificial general intelligence for the benefit of all. The company does not believe that the beneficial advancement of AI is unavoidable, and Faathom believes that as a company offering a critical layer in the AI technology stack, we can make a difference in how securely advanced AI systems are built and deployed.

SCiFi Foods

Venture Round in 2020
SCiFi Foods is a food technology company creating transformational products by combining cultivated meat with plant-based ingredients to make burgers shockingly close to the taste of conventional beef. Already, it has successfully grown beef cells in suspension, which at scale will reduce its cost of production by 1000x—a massive milestone. It was co-founded by CEO Joshua March, a serial entrepreneur with two prior exits, and CTO Kasia Gora, PhD., who has led R&D teams in bioengineering for more than a decade, most recently at Zymergen. To date, it has raised $29M from leading investors, including Andreessen Horowitz, Valor Siren Ventures, BoxGroup, Entree Capital, and Prelude Ventures, amongst others.

Twelve

Seed Round in 2019
Twelve is a carbon transformation company converting captured carbon dioxide into valuable chemicals, fuels, and other essential products. Their technology eliminates emissions by turning CO2 into essential products that are made from fossil fuels. They specialize in the fields of CO2 electrocatalysis and electrochemical reactor design.

Cervest

Seed Round in 2019
Cervest's AI-powered Climate Intelligence platform and EarthScan(TM) product put the power of a thousand climate scientists into the hands of decision makers across businesses, governments, insurance companies and financial markets to help them quantify, manage and adapt to climate change at an asset-level. We are a Certified B Corporation with a vision to democratize access to Climate Intelligence through our open access platform, driving a shared responsibility to protect the world’s critical assets. Cervest is backed by mission-aligned investors, including Astanor Ventures, Lowercarbon Capital, Future Positive Capital, Draper Espirit and UNTITLED. Discover how current and future climate events such as flooding, droughts, and extreme temperatures will impact the assets you own, manage, or depend on. Learn more at cervest.earth.

Beam

Seed Round in 2019
Beam is a micro-mobility startup that encourages users to park their e-scooters in pre-determined parking spots via its app by offering incentives, instead of parking it anywhere randomly on the street.

Heart Aerospace

Seed Round in 2019
Heart’s mission is to create the fastest, most affordable and sustainable transportation for regional travel to every corner of the world. Their first aircraft is the ES-19, a nineteen-passenger airliner with an operating range of 400 km. Heart's goal is to have the aircraft certified for commercial operation by 2026.

Golden

Seed Round in 2019
Golden is a developer of a self-constructing knowledge database used to accelerate discovery and education. The company uses and leverages human effort by using machine intelligence to make the process of gathering and communicating knowledge simpler. It combines a powerful search across several entities with fine-grain alerts to stay on top of changes, and semi-automatic research assistance for gaps in knowledge that enable people in organizations to stay current, understand and leverage the latest trends in their industry.

Shiok Meats

Seed Round in 2019
Shiok Meats is cellular aquaculture and cell-based meat company. With a mission to bring clean and healthy meats and seafood by harvesting from cells instead of animals. Shiok Meats brings cell-based crustacean meats that are animal-, health- and environment-friendly. Shiok Meats was founded in 2018 and is headquartered in Central Region, Singapore.

ZeroDown

Seed Round in 2019
ZeroDown is a real estate startup that focuses on providing an affordable homeownership solution. It is an alternative to the rent-or-own dilemma, offering the benefits of homeownership with the flexibility of renting. It was founded in 2018 by Abhijeet Dwivedi (Previously COO and CSO at Zenefits, McKinsey), Hari Viswanathan (Previously Staff Engineer at Zenefits) and Laks Srini (Previously Co-founder and CTO at Zenefits, SigFig and D. E. Shaw & Co). The three founders worked together at Zenefits -- which processes $2B+ a year in payroll for SMBs, provides access to healthcare and insurance for 100,000+ employees and serves more than 10,000 SMBs.

Good Money

Series A in 2019
Good Money is a digital banking platform that provides banking and financial services that will be owned by its customers and will invest 50% of profits to actively protect the environment and fight for social justice.

Wright Electric

Seed Round in 2019
Wright Electric's unique propulsion technology and forthcoming airplanes eliminate emissions without the need for offsets, lowering the cost of zero-emissions flight to the same level as running a fossil-fueled fleet and ushering in the next age of aviation through the electrification of the aerospace sector.

Calm

Series A in 2018
Calm offers an application designed to help its users meditate and relax. The company is driven by a mission to make the world happier and healthier by developing a range of digital and physical products that enhance mental fitness and alleviate some of the most important mental health issues of the modern age including anxiety, depression, insomnia, and stress. Calm was named by Apple as the 2017 iPhone App of the Year and by Google Play as an Editors’ Choice in 2018. The company was founded in 2012 and is headquartered in San Francisco, California.

Pelago

Seed Round in 2018
Pelago, formerly Quit Genius, is the world’s leading virtual clinic for substance use management. We are transforming substance use support—from prevention to treatment—delivering education, management skills, and opportunities for positive change to members struggling with substance use, most commonly tobacco, alcohol, or opioids. Our solution gives employers the means to offer on-demand, personalized support to workers seeking to live healthier lives. Pelago’s cognitive behavioral therapy (CBT) and medication-assisted treatment (MAT) programs deliver convenient, accessible, and effective support that seamlessly integrates with health plans, pharmacy benefit managers, and wellness platforms. To date, Pelago has helped more than 750,000 members manage their substance use and improve their lives.
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