Longevitytech.fund

Klothea Bio is a protein well known for its powerful anti-aging capabilities, such as tumor suppression, neuroprotection, and antioxidative actions. As people age, their klotho levels drop to harmful levels. The metabolic disease syndrome will be the focus of the first investigations, while later studies will try to extend therapeutic applications to cancer, Alzheimer's disease, obesity, and other age-related diseases.

Yuva Biosciences is a company focused on restoring mitochondrial function to combat the effects of aging, particularly in hair and skin. It specializes in the development of cosmeceuticals and pharmaceuticals aimed at addressing issues such as aging-related hair loss, wrinkled skin, and diminished energy levels. By leveraging advancements in mitochondrial science, Yuva Biosciences creates products that aim to rejuvenate users, promoting healthier hair and skin while counteracting the visible signs of aging.

MitoRx Therapeutics is a biotechnology company focused on developing innovative therapeutics aimed at reversing mitochondrial dysfunction. The company specializes in creating mitochondrial-protective treatments for a range of conditions, including neuromuscular disorders, metabolic diseases, and dementia. By targeting the underlying mitochondrial issues associated with these challenging diseases, MitoRx Therapeutics seeks to enable healthcare professionals to halt the progression of conditions such as dystrophy and neurodegeneration. In addition to its internal research on rare indications, the company also collaborates on broader health issues, positioning itself as a key player in the field of mitochondrial medicine.

Rejuvenation Technologies Inc., established in 2016 and based in Mountain View, California, is a biotechnology company specializing in developing nucleoside-modified TERT mRNA. This technology safely and rapidly extends telomeres, enabling cells to proliferate more effectively. The company focuses on regenerative medicine applications, aiming to target age-related diseases and conditions across various organs such as the liver, lungs, and immune system. Their offerings include cell therapies like tissue engineering, transplants, skin grafts, immunotherapy, and regeneration medicine.

SiPhox Health, based in Cambridge, Massachusetts, specializes in designing and manufacturing innovative diagnostic solutions. The company develops next-generation diagnostics infrastructure, including at-home test kits and central lab systems. Their flagship product is a disposable biosensor cartridge that assesses 17 blood biomarkers, providing insights into inflammation, hormonal health, metabolic fitness, and cardiovascular health. SiPhox Health's platform merges biochemistry, photonic chip technology, integrated photonics, electronics, and microfluidics to enable sensitive readouts of immunoassays and nucleic acid tests, facilitating point-of-need and at-home diagnostics.

Cosmica Biosciences focuses on accelerating drug discovery aimed at enhancing human longevity and resilience, particularly in the context of deep space exploration. The company employs a platform that combines unbiased multi-scale biology with machine learning algorithms to create precision-based interventions designed to extend human lifespan and mitigate health risks associated with spaceflight. Utilizing data from human blood and organoids exposed to microgravity and galactic radiation, as well as in vivo data from commercial and non-commercial crew members and NASA-sponsored experiments, Cosmica Biosciences aims to bridge the gap between geriatric care and the unique health challenges posed by space travel. Their comprehensive approach includes multi-omic monitoring, biomarker identification, and target validation to address the complexities of aging and health in both terrestrial and extraterrestrial environments.

Cleara Biotech B.V. is a biotechnology company based in Utrecht, the Netherlands, focused on developing innovative therapeutics to selectively eliminate senescent and senescent-like cancer cells. The company specializes in creating FOXO4-based anti-senescence drugs aimed at addressing chemotoxicity and combating therapy-resistant cancer cells. Cleara Biotech's research targets a crucial aspect of cancer treatment by aiming to enhance the effectiveness of therapies and improve patient outcomes through the targeted removal of problematic cell populations.

Remedium Bio is a Boston-based gene therapy company dedicated to developing curative treatments for a variety of debilitating conditions. The company employs a unique approach that combines established technologies in innovative ways to address well-defined disease mechanisms. By modularly applying these proven technologies, Remedium Bio focuses on creating localized and targeted therapies centered on clinically validated molecules and pathways. Its pipeline includes leading gene therapy candidates in multiple fields, such as rheumatology, endocrinology, and neurology, aimed at providing effective treatments for a range of immune, age-related, and metabolic disorders.

Senisca is a senotherapeutics company established in 2020, focused on developing anti-aging oligonucleotide therapeutics. The company aims to provide innovative pharmaceutical treatments for age-related chronic diseases by creating a new generation of oligonucleotide-based interventions. These therapeutics target the underlying mechanisms of aging, restoring the ability of cells to regulate gene expression effectively. By rejuvenating aged cells, Senisca seeks to improve healthspan and address both the diseases and aesthetic manifestations of aging, ultimately enabling individuals to live healthier for longer periods.

MitoRx Therapeutics is a biotechnology company focused on developing innovative therapeutics aimed at reversing mitochondrial dysfunction. The company specializes in creating mitochondrial-protective treatments for a range of conditions, including neuromuscular disorders, metabolic diseases, and dementia. By targeting the underlying mitochondrial issues associated with these challenging diseases, MitoRx Therapeutics seeks to enable healthcare professionals to halt the progression of conditions such as dystrophy and neurodegeneration. In addition to its internal research on rare indications, the company also collaborates on broader health issues, positioning itself as a key player in the field of mitochondrial medicine.

Sampling Human is a biotechnology company that develops computational tools to measure and analyze complex single-cell and spatial omic data on an industrial scale. Their technology enables pre-symptomatic screening, personalized medicine, and drug discovery by translating vast amounts of genetic analysis data into practical applications in fields such as diagnostics and bioengineering.

Celeris Therapeutics is an AI-first drug discovery company that focuses on developing proximity-inducing compounds (PICs), particularly PIC degraders, to address high unmet medical needs in diseases like Parkinson's and various cancers. The company has created the Celeris One platform, which utilizes structure-based geometric deep learning to enhance the design and development of degraders by prioritizing specific E3 ligases, designing effective linkers, and selecting optimal compounds for synthesis. Additionally, Celeris Therapeutics operates an in-house automated laboratory that facilitates rapid generation of experimental data for further optimization. The company collaborates with pharmaceutical and biotech firms to discover and develop small-molecule degrader therapies across multiple therapeutic areas, while also advancing its own internal drug pipeline. Celeris Therapeutics maintains offices in Menlo Park, California, and Graz, Austria.

Brainkey is a developer of a digital therapeutics platform focused on improving diagnosis and treatment of brain diseases. The company utilizes AI-derived brain biomarkers to provide personalized treatment recommendations, aiming to enhance brain longevity. By analyzing brain data at a petabyte scale, Brainkey's cloud-based technology facilitates informed clinical and pharmaceutical decision-making. This innovative approach enables patients and healthcare providers to access advanced brain care and analysis, ultimately transforming the landscape of brain disease management.

SiPhox Health, based in Cambridge, Massachusetts, specializes in designing and manufacturing innovative diagnostic solutions. The company develops next-generation diagnostics infrastructure, including at-home test kits and central lab systems. Their flagship product is a disposable biosensor cartridge that assesses 17 blood biomarkers, providing insights into inflammation, hormonal health, metabolic fitness, and cardiovascular health. SiPhox Health's platform merges biochemistry, photonic chip technology, integrated photonics, electronics, and microfluidics to enable sensitive readouts of immunoassays and nucleic acid tests, facilitating point-of-need and at-home diagnostics.

Collaborate Healthcare is a technology startup focused on enhancing clinical outcomes for pediatricians and general practitioners through innovative IT solutions. The company has developed a healthcare platform that includes patient relationship management (CRM) and collaboration tools, designed to transform medical care delivery into a technology-driven, patient-centered, team-based approach. By facilitating communication among medical practitioners, the platform allows for second opinions and helps to minimize diagnostic errors. It also supports seamless patient follow-up, ensuring that healthcare providers can deliver comprehensive care experiences.

Zoe Biosciences is a biotechnology company dedicated to developing therapeutics aimed at age-related diseases and the aging process itself. Its innovative platform targets the PAI-1/apelin axis, which enables direct intervention in the mechanisms of aging. By focusing on longevity therapeutics, Zoe Biosciences seeks to empower healthcare providers with the tools necessary to prevent or delay the onset of various chronic diseases, thereby improving overall health outcomes for aging populations.

Rejuvenation Technologies Inc., established in 2016 and based in Mountain View, California, is a biotechnology company specializing in developing nucleoside-modified TERT mRNA. This technology safely and rapidly extends telomeres, enabling cells to proliferate more effectively. The company focuses on regenerative medicine applications, aiming to target age-related diseases and conditions across various organs such as the liver, lungs, and immune system. Their offerings include cell therapies like tissue engineering, transplants, skin grafts, immunotherapy, and regeneration medicine.

Cleara Biotech B.V. is a biotechnology company based in Utrecht, the Netherlands, focused on developing innovative therapeutics to selectively eliminate senescent and senescent-like cancer cells. The company specializes in creating FOXO4-based anti-senescence drugs aimed at addressing chemotoxicity and combating therapy-resistant cancer cells. Cleara Biotech's research targets a crucial aspect of cancer treatment by aiming to enhance the effectiveness of therapies and improve patient outcomes through the targeted removal of problematic cell populations.

Petri Bio is a biotechnology company focused on developing therapeutics derived from gut microbes. The company specializes in screening beneficial microbial genomes to identify and optimize useful compounds for healthcare applications. By harnessing the unique properties of these microbes, Petri Bio aims to enhance treatment options for various diseases, thereby enabling physicians to provide more effective care. Through its innovative approach, the company seeks to improve health outcomes by leveraging the potential of microbe-based products in medical treatments.

Maxwell Biosciences is a preclinical-stage drug platform company focused on developing innovative therapeutics through its proprietary CLAROMER biotechnology platform. This technology generates low-molecular-weight compounds that mimic peptides, offering a distinct advantage over traditional macromolecules by facilitating easier membrane penetration. The company aims to create biomimetic therapeutics and synthetic compounds that effectively target and destroy viruses, bacteria, fungi, and certain cancers while preserving healthy cells. By imitating essential components of the immune system, Maxwell Biosciences enables healthcare professionals to address conditions that were previously deemed untreatable, positioning itself as a pioneer in the field of advanced therapeutics.

Juvena Therapeutics, Inc. is a biopharmaceutical company based in San Mateo, California, founded in 2017. The company focuses on developing protein-based therapeutics aimed at promoting tissue rejuvenation, primarily targeting age-related conditions such as sarcopenia, wound healing, and neural regeneration. Juvena Therapeutics utilizes a drug discovery platform that screens for restored cellular functions to create innovative therapeutics that facilitate tissue regeneration and repair. By decoding secreted proteins, the company aims to address various chronic and rare diseases, ultimately enhancing the quality of life for elderly patients.

Intervene Immune is a biotechnology company focused on developing innovative therapies aimed at regenerating the thymus and addressing age-related decline in immune function. The company specializes in immuno-therapies that educate bone marrow-derived cells to differentiate into T cells, which play a crucial role in the body's defense against pathogens such as bacteria and viruses. Intervene Immune employs techniques to reverse thymic involution and epigenetic aging, thereby enhancing the immune response in older individuals. By providing effective methods for immune system regeneration, the company aims to improve health outcomes for the elderly and strengthen their ability to combat infections and tumors.

NOVOS is a brand focused on longevity supplements, aiming to enhance users' lives through science-backed products designed to slow down aging processes. Their offerings include healthcare drinks enriched with anti-aging ingredients like nicotinamide riboside, magnesium, fisetin, and pterostilbene, along with antioxidants and other functional components that facilitate DNA repair and reduce damage, thereby potentially extending lifespan and improving overall health.

Occuity Ltd is a company focused on the research, design, and manufacture of non-contact optical instruments for healthcare diagnostics and monitoring. Established in 2019 and based in Reading, United Kingdom, Occuity develops a range of handheld optical devices, including pachymeters, pupillometers, and keratometers, which are used in both human and veterinary optometry. These instruments function by projecting light into the eye and analyzing the reflected signals, allowing for direct measurements that assist optometrists and ophthalmologists. Additionally, Occuity's technology facilitates the monitoring of various health conditions, such as diabetes and Alzheimer’s disease, thereby enhancing the effectiveness and accessibility of diagnostic and screening tools in healthcare.

Samsara Therapeutics, founded in 2018 with operations across Europe and San Diego, is a biopharmaceutical company dedicated to discovering and developing therapeutics for age-related diseases and unmet medical needs. Its proprietary platform focuses on identifying and validating compounds that extend healthy lifespan by targeting fundamental aging processes such as proteostasis and autophagy. The company aims to create novel treatments for rare genetic and neurodegenerative diseases through its pipeline, which involves compound identification, chemical optimization, and in vivo validation across various species.

Embrace Prevention Care is a healthcare service provider specializing in chronic illness management for elderly individuals. They offer regular consultations with nurse practitioners and pharmacists to monitor health conditions like heart failure. Their approach involves tracking patient progress across various aspects to identify potential issues early, aiming to prevent serious complications, reduce hospitalizations, and promote independent living.

VasoDynamics is a company focused on developing cancer-preventive therapies aimed at enhancing the standard of cancer care. It offers radioprotection programs that are protected by international patents, grounded in innovative research and affordable medications. These programs are designed to help patients and medical professionals mitigate the common side effects associated with cancer therapies, thereby improving treatment outcomes and enhancing the overall quality of life for patients. VasoDynamics is committed to advancing cancer care through its unique therapeutic solutions.

The speed of research and product development is dramatically increasing. Most of that advancement is done by small, new companies - startups. These companies have no capacity to build worldwide distribution channels and the availability of their products is local and very limited. It is not even feasible for health professionals like physicians, clinics or specialized shops to buy directly, often oversee these emerging products. Diagnostic products mostly require sample collection or specialized laboratory preprocessing before shipping. We provide standardized or bespoke solutions for full selling life cycle of longevity products: - Market Research and Recommendations - Local Compliance - Local Brand Creation - Pre-contracted Local Distribution Channels or Direct Customers - Complete Logistics Solution - Sample Collection and Laboratory Processing

With modern science, we’ve come to realize that the secret to a fuller life is individual to each and every one of us. So what if you could wake up in the morning and before you’ve had your coffee or breakfast, your sidekick already knows how you are feeling – your energy levels, how you slept, how busy your day will be. What if it knew exactly what you needed to do to fill in missing nutrient gaps or give yourself the boost you need for your busy day? And you didn’t have to do anything yourself. What if you could achieve this by simply adjusting your morning breakfast order? Welcome to Healthy Longevity Café – a first of its kind integrated concept; combining highly accurate AI-powered data measurements (from behavioral assessments & medical tests) that serve as a guide for a personalized health plan (developed by healthcare professionals). We provide wellness guidance and serve you tasty superfoods infused with your daily dose of supplements and guarantee to give you exactly what your body needs. We are providing a Personalized Recipe for Longevity, available to everyone – globally. Healthy Longevity Café is a VC-backed company.

Healthy Longevity Guide is an educational platform for medical learning. They offer education, webinars, patient handouts, a marketplace, a catalog of medicine, courses, and certification.

We aspire to be a leading applied research organization in the field of advanced integrated and personalized therapies. With clinics in Europe and US, we work closely with research organizations to execute clinical trials and formulate advanced clinical programs.

Celeris Therapeutics is an AI-first drug discovery company that focuses on developing proximity-inducing compounds (PICs), particularly PIC degraders, to address high unmet medical needs in diseases like Parkinson's and various cancers. The company has created the Celeris One platform, which utilizes structure-based geometric deep learning to enhance the design and development of degraders by prioritizing specific E3 ligases, designing effective linkers, and selecting optimal compounds for synthesis. Additionally, Celeris Therapeutics operates an in-house automated laboratory that facilitates rapid generation of experimental data for further optimization. The company collaborates with pharmaceutical and biotech firms to discover and develop small-molecule degrader therapies across multiple therapeutic areas, while also advancing its own internal drug pipeline. Celeris Therapeutics maintains offices in Menlo Park, California, and Graz, Austria.

Senisca is a senotherapeutics company established in 2020, focused on developing anti-aging oligonucleotide therapeutics. The company aims to provide innovative pharmaceutical treatments for age-related chronic diseases by creating a new generation of oligonucleotide-based interventions. These therapeutics target the underlying mechanisms of aging, restoring the ability of cells to regulate gene expression effectively. By rejuvenating aged cells, Senisca seeks to improve healthspan and address both the diseases and aesthetic manifestations of aging, ultimately enabling individuals to live healthier for longer periods.

Yuva Biosciences is a company focused on restoring mitochondrial function to combat the effects of aging, particularly in hair and skin. It specializes in the development of cosmeceuticals and pharmaceuticals aimed at addressing issues such as aging-related hair loss, wrinkled skin, and diminished energy levels. By leveraging advancements in mitochondrial science, Yuva Biosciences creates products that aim to rejuvenate users, promoting healthier hair and skin while counteracting the visible signs of aging.

GenFlow Biosciences is a preclinical biotechnology company specializing in synthetic biology and gene therapies aimed at delaying or halting the aging process in both humans and canines. The company is dedicated to developing innovative biological interventions that target the biological mechanisms of aging, with the goal of extending life expectancy and combating age-related diseases. By focusing on longevity and the creation of effective treatments, GenFlow Biosciences seeks to address the challenges associated with aging and improve overall health outcomes for individuals as they age.

Sensable Health is a provider of health and wellness services focused on delivering a balanced, scientific, and personalized approach to weight management. The company offers an AI-driven mobile application designed to cater to individual goals and unique biological factors, taking into account specific lifestyle considerations. This program includes customized support, digital coaching, and various resources aimed at helping users alter their metabolic state. By emphasizing sustainable weight loss and long-term wellness, Sensable Health seeks to improve users' overall well-being, enabling them to look better, feel better, and lead healthier lives.

Vesttoo Ltd is a Tel Aviv-based company that operates an artificial intelligence-driven financial risk management platform. Established in 2018, Vesttoo focuses on creating a marketplace for non-catastrophic insurance-based risk transfer and investments, connecting insurance companies with institutional investors. Its proprietary technology enhances risk transfer and liquidity in the life and property & casualty insurance markets by facilitating faster deal structuring, risk modeling, pricing, and index calculation. Vesttoo provides a range of solutions that cater to the legal, regulatory, and accounting needs of its clients, which include insurers, reinsurers, and pension funds. By offering asset managers access to diverse, uncorrelated investment options linked to insurance and reinsurance premiums, the company positions itself as a significant alternative to traditional reinsurance models. Vesttoo's innovation has garnered recognition through participation in prestigious fintech accelerators and collaborations with industry leaders, further establishing its role in merging insurance with capital market dynamics.

Pano Therapeutics is a biotechnology company focused on the development of small molecule drugs aimed at treating rare and prevalent chronic diseases, particularly those related to aging and metabolic dysfunction. The company's innovative platform is designed to discover biguanides and other compounds that target mitochondrial ion channels and organic cation transporters, enhancing drug potency and selective tissue exposure. Pano Therapeutics is engaged in the clinical development of therapies for complex disease states, including various cancers and kidney diseases, leveraging its preclinical assets to provide improved treatment options for a diverse range of health conditions. Through its research, the company aims to advance the understanding and treatment of diseases associated with cellular energetics.

Mitrix bio is a mitochondrial dysfunction that has been implicated in chronic diseases such as Alzheimer’s, macular degeneration, immune senescence, liver and kidney dysfunction, cardiovascular disease, frailty, mitochondrial mutation diseases, and more.

Repair Biotechnologies, Inc. is a biotechnology company founded in 2018 and based in Syracuse, New York. The company focuses on developing innovative therapies aimed at reversing the progression of age-related conditions such as immunosenescence and atherosclerosis. Utilizing a cholesterol-degrading platform, Repair Biotechnologies creates treatments that address conditions driven by excess or modified cholesterol, including atherosclerosis and familial hypercholesterolemia. Their approach centers on gene therapy and recombinant protein strategies, designed to be safe and well-tolerated, allowing patients to target the underlying causes of diseases associated with cholesterol accumulation.

Yolife GmbH is a Berlin-based company founded in 2017 that develops a mobile application aimed at promoting good health through lifestyle changes, professional consultations, and medical therapies. The app, available on both the App Store and Google Play, leverages insights from over 300 scientific studies to provide users with personalized fitness, nutrition, and wellness guidance. Yolife's mission is to help one billion people add 15 healthy years to their lives by making life-extending practices easy and accessible. Users can create custom action plans, earn rewards for adhering to dietary recommendations, and unlock deals from health product and service providers, all while enhancing their overall health and longevity.

First Longevity provides daily news and insights on the fast-growing longevity market. They offer antiaging, biotech, research, investment, supplements, and rejuvenation therapies. They offer news under diverse categories including AI, nanotechnology, drugs, agritech, and investment, along with monetizing its contents through display advertisements.

Syd is a tech company that develops predictive health technology for organizations and employees. It uses AI to analyze aggregated employee data and provide personalized recommendations, aiming to enhance life quality, boost productivity, reduce absenteeism, and improve overall business outcomes by supporting better talent strategies.

Life Biosciences is a biotechnology company focused on developing drug therapies aimed at promoting longevity and treating age-related diseases. The company's approach addresses the systemic breakdown of the body due to aging, targeting the eight pathways of age-related decline. By considering health decline as an interconnected process rather than a collection of isolated issues, Life Biosciences seeks to empower senior citizens to combat various age-related conditions, ultimately striving to extend healthy life spans.

Animal Bioscience is a company focused on developing innovative products aimed at enhancing the health and longevity of animals, particularly pets and cattle. The firm specializes in creating medical compounds and treatments that utilize advanced technologies to monitor physical activity and behavior in animals. By addressing the symptoms of aging, Animal Bioscience seeks to prolong the youth and expand the lifespan of animals, thereby improving overall well-being for pet and livestock owners.

Nightingale Health is a global health technology company dedicated to transforming preventive care through innovative blood-testing services. By providing comprehensive health insights, it enables individuals to identify disease risks and assess the impact of lifestyle changes that standard lab tests may overlook. The company's Health Data Platform connects healthcare providers with the preventative health needs of individuals, fostering informed decision-making and encouraging proactive health management. Nightingale Health's approach emphasizes the importance of maintaining health rather than merely addressing illnesses, ultimately contributing to scientific advancements and promoting positive lifestyle changes among users.

AgeCurve is a company focused on advancing healthy longevity through a platform that integrates single-cell genomics and transcriptomics. This innovative approach allows for the quantification of thousands of human proteins, which aids in assessing various aspects of biological aging. AgeCurve's technology generates diagnostic reports for clinical use, offering valuable insights that facilitate the identification of drug repurposing candidates. By bridging the gap between aging diagnostics and therapeutics, the company aims to enhance the quality control of cell therapies and contribute to advancements in the field of aging research.

Gerostate Alpha Incorporated is a pharmaceutical company focused on developing treatments for aging and age-related diseases. Founded in 2018 and based in Novato, California, the company was established by three co-founders who are academics at the Buck Institute, where they have dedicated years to researching the biology of aging. Gerostate Alpha employs a proprietary drug discovery platform that has allowed it to analyze 90,000 compounds, resulting in the identification of 150 potential drug candidates for further investigation. Through its innovative approach, the company aims to create pharmaceutical solutions that enhance both lifespan and health span, helping patients manage and reduce the impacts of aging.