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Klothea Bio is a protein well known for its powerful anti-aging capabilities, such as tumor suppression, neuroprotection, and antioxidative actions. As people age, their klotho levels drop to harmful levels. The metabolic disease syndrome will be the focus of the first investigations, while later studies will try to extend therapeutic applications to cancer, Alzheimer's disease, obesity, and other age-related diseases.

Yuva Biosciences specializes in developing cosmeceutical and pharmaceutical products aimed at addressing aging-related issues such as hair loss and skin wrinkles. The company focuses on restoring mitochondrial function, which is essential for cellular energy and health, to rejuvenate hair and skin. By leveraging mitochondrial science, Yuva Biosciences creates innovative solutions designed to counteract the symptoms of aging, enabling individuals to regain youthful vitality and appearance.

MitoRx Therapeutics is a biotechnology company that focuses on developing innovative therapeutics aimed at reversing mitochondrial dysfunction. The company targets various conditions, including neuromuscular disorders, metabolic diseases, and dementia. By specializing in mitochondrial-protective therapies, MitoRx seeks to address the underlying causes of these challenging diseases. The company is committed to both developing treatments for rare indications and forming partnerships to tackle broader health issues. Through its efforts, MitoRx aims to enable healthcare professionals to halt the progression of conditions associated with dystrophy and neurodegeneration.

Rejuvenation Technologies Inc. is a biotechnology company based in Mountain View, California, focused on developing nucleoside-modified telomerase reverse transcriptase messenger RNA to extend telomeres and promote human health. The company's innovative approach involves delivering a telomere extender that encodes telomerase reverse transcriptase, which transiently boosts telomerase activity in cells. This technology aims to enhance the proliferative capacity of cells, potentially addressing age-related diseases and conditions in various medical fields, including hepatic, pulmonary, and immunology. Additionally, Rejuvenation Technologies offers a range of cell therapies that encompass tissue engineering, cell transplants, skin grafts, immunotherapy, and regenerative medicine. Established in 2016, the company is dedicated to advancing solutions in regenerative health.

SiPhox Health develops advanced diagnostic solutions for both home use and laboratory settings. The company offers an at-home test kit that evaluates 17 blood biomarkers, focusing on areas such as inflammation, hormonal health, metabolic fitness, and cardiovascular health. Their biosensing platform features a handheld device designed to work with disposable cartridges, integrating biochemistry and photonic chip technology. This innovative approach combines integrated photonics, electronics, and microfluidics to deliver sensitive readings of immunoassays and nucleic acids, facilitating point-of-need testing and enhancing the accessibility of diagnostic tools for users.

Cosmica Biosciences focuses on accelerating drug discovery aimed at enhancing human longevity and resilience, particularly in the context of deep space exploration. The company employs a unique platform that combines unbiased multi-scale biology with machine learning algorithms, facilitating the development of precision-based interventions to extend human lifespan and mitigate health risks associated with spaceflight. By utilizing data from human blood, organoids subjected to microgravity simulations, and galactic radiation, along with in vivo data from both commercial and non-commercial crew members and experiments conducted by NASA, SpaceX, and Axiom, Cosmica aims to bridge the gap between geriatric health and spaceflight pathology. Its methodologies include multi-omic monitoring, biomarker identification, and target validation, which are designed to address the accelerated pace of cellular and organismal aging.

Cleara Biotech B.V., based in Utrecht, the Netherlands, focuses on developing therapeutics aimed at selectively eliminating senescent and senescent-like cancer cells. The company is particularly engaged in creating FOXO4-based anti-senescence drugs designed to counteract chemotoxicity and address therapy-resistant cancer cells. By targeting these problematic cells, Cleara Biotech seeks to advance cancer treatment and improve patient outcomes.

Remedium Bio is a Boston-based gene therapy company dedicated to developing curative treatments for various debilitating conditions. The company employs a modular approach to research and development, utilizing established technologies in innovative ways to address well-understood disease mechanisms. By focusing on clinically validated molecules and targeted treatment strategies, Remedium Bio aims to create effective therapies for conditions within rheumatology, endocrinology, and neurology. Its pipeline includes promising gene therapy candidates designed to tackle a wide range of diseases, including immune and age-related disorders.

Senisca is a biotech start-up. They propose to create a new generation of oligonucleotide-based interventions to rewind the clock in old cells and target diseases and cosmetic signs of aging. They provide molecular and cellular biology and have patent-protected an innovation for the reversal of cellular senescence.

MitoRx Therapeutics is a biotechnology company that focuses on developing innovative therapeutics aimed at reversing mitochondrial dysfunction. The company targets various conditions, including neuromuscular disorders, metabolic diseases, and dementia. By specializing in mitochondrial-protective therapies, MitoRx seeks to address the underlying causes of these challenging diseases. The company is committed to both developing treatments for rare indications and forming partnerships to tackle broader health issues. Through its efforts, MitoRx aims to enable healthcare professionals to halt the progression of conditions associated with dystrophy and neurodegeneration.

Sampling Human specializes in developing advanced technologies for genetic analysis, focusing on complex single-cell and spatial omic data. The company aims to create compute-driven products that facilitate the measurement and analysis of this data at an industrial scale. Through its innovative solutions, Sampling Human supports various applications in pre-symptomatic screening, personalized medicine, drug discovery, and basic science. This approach enables healthcare professionals to effectively translate extensive datasets into practical applications in diagnostics and bioengineering, ultimately enhancing the capabilities of physicians in addressing complex medical challenges.

Celeris Therapeutics is an AI-driven drug discovery company focused on developing proximity-inducing compounds (PICs), particularly PIC degraders, to address diseases with significant unmet medical needs, including Parkinson's disease and various cancers. The company utilizes its proprietary Celeris One platform, which employs structure-based geometric deep learning to enhance the design and development of degraders. This platform aids in the prioritization of specific E3 ligases, the design of linkers, and the selection of the most promising compounds for synthesis. Additionally, Celeris Therapeutics operates an automated laboratory that rapidly generates experimental data for further optimization. The company collaborates with pharmaceutical and biotech firms to co-develop small-molecule degrader therapies across various therapeutic areas while also building its own drug pipeline. Celeris Therapeutics maintains offices in Menlo Park, California, and Graz, Austria.

BrainKey is focused on advancing brain longevity through a digital therapeutics platform that utilizes AI-derived brain biomarkers to provide personalized treatment recommendations. The company aims to transform the diagnosis and treatment of brain diseases by interpreting extensive brain data at a petabyte scale. This cloud-based technology enhances clinical and pharmaceutical decision-making, ultimately improving access to superior brain care and analysis for patients and healthcare facilities.

SiPhox Health develops advanced diagnostic solutions for both home use and laboratory settings. The company offers an at-home test kit that evaluates 17 blood biomarkers, focusing on areas such as inflammation, hormonal health, metabolic fitness, and cardiovascular health. Their biosensing platform features a handheld device designed to work with disposable cartridges, integrating biochemistry and photonic chip technology. This innovative approach combines integrated photonics, electronics, and microfluidics to deliver sensitive readings of immunoassays and nucleic acids, facilitating point-of-need testing and enhancing the accessibility of diagnostic tools for users.

Collaborate Healthcare is a technology startup that develops IT solutions for pediatricians and general practitioners. The company focuses on clinical outcomes through teamwork-oriented and patient-centered workflows. Its products also focuses communication and collaboration among healthcare providers, supporting efficient patient care.

Zoe Biosciences is focused on developing a platform for longevity therapeutics aimed at addressing age-related diseases. The company specifically targets the apelin axis, which plays a crucial role in aging, allowing healthcare providers to prevent or delay the onset of various chronic diseases. By concentrating on this innovative approach, Zoe Biosciences seeks to enhance health outcomes and longevity for individuals as they age.

Rejuvenation Technologies Inc. is a biotechnology company based in Mountain View, California, focused on developing nucleoside-modified telomerase reverse transcriptase messenger RNA to extend telomeres and promote human health. The company's innovative approach involves delivering a telomere extender that encodes telomerase reverse transcriptase, which transiently boosts telomerase activity in cells. This technology aims to enhance the proliferative capacity of cells, potentially addressing age-related diseases and conditions in various medical fields, including hepatic, pulmonary, and immunology. Additionally, Rejuvenation Technologies offers a range of cell therapies that encompass tissue engineering, cell transplants, skin grafts, immunotherapy, and regenerative medicine. Established in 2016, the company is dedicated to advancing solutions in regenerative health.

Cleara Biotech B.V., based in Utrecht, the Netherlands, focuses on developing therapeutics aimed at selectively eliminating senescent and senescent-like cancer cells. The company is particularly engaged in creating FOXO4-based anti-senescence drugs designed to counteract chemotoxicity and address therapy-resistant cancer cells. By targeting these problematic cells, Cleara Biotech seeks to advance cancer treatment and improve patient outcomes.

Petri Bio is a biotechnology company focused on developing therapeutics derived from gut microbes. The company specializes in screening beneficial microbial genomes to uncover useful compounds and optimizing these for medical applications. By harnessing the potential of gut microbiota, Petri Bio aims to enhance treatment options for a variety of diseases, providing healthcare professionals with innovative solutions to improve patient outcomes.

Juvena Therapeutics, Inc. is a biopharmaceutical company based in San Mateo, California, founded in 2017. The company specializes in developing protein-based therapeutics aimed at promoting tissue rejuvenation and addressing age-related diseases in the elderly. Its innovative platform focuses on discovering novel therapeutics that restore cellular functions, targeting conditions such as sarcopenia, wound healing, and neural regeneration. By decoding secreted proteins, Juvena Therapeutics aims to provide solutions for chronic and rare diseases, enhancing the quality of life for aging populations.

NOVOS is a Longevity supplements brand. Its goal is to help people live longer, healthier lives by developing science-based products that slow down the aging process.

Intervene Immune is focused on developing innovative treatments aimed at regenerating the thymus and addressing age-related immune system decline. The company specializes in immunotherapies and diagnostics designed to reverse thymic involution and epigenetic aging, thereby enhancing the body's ability to combat foreign invaders such as bacteria and viruses. By educating bone marrow-derived cells to transform into functional T cells, Intervene Immune provides methods for immune system regeneration, particularly beneficial for healthy elderly individuals. The company's approach not only aims to improve immune responses but also plays a role in targeting tumors, contributing to overall health and resilience against infections.

Occuity Ltd is a company based in Reading, United Kingdom, that focuses on the research, design, and manufacture of non-contact optical instruments for healthcare diagnostics and monitoring. Founded in 2019, it offers a range of handheld devices, including pachymeters, pupillometers, and keratometers, which are utilized in both human and veterinary optometry. These instruments employ light to analyze the eye, facilitating direct measurements that assist optometrists and ophthalmologists in diagnosing and monitoring various health conditions, such as diabetes and Alzheimer's disease. By providing innovative non-contact solutions, Occuity aims to enhance the effectiveness and accessibility of diagnostic and screening technologies in the healthcare sector.

Embrace Prevention Care specializes in delivering personalized preventive care services aimed at older adults with chronic illnesses, such as heart failure. The company provides consistent interaction with dedicated nurse practitioners and pharmacists, ensuring comprehensive support for patients facing complex health challenges. Through regular monitoring and recording of vital signs, Embrace Prevention Care tracks patient progress across multiple dimensions, allowing for the early identification of potential health issues. By promoting habit changes and meaningful preventive actions, the organization helps older adults maintain their independence, reduce hospitalizations, and safely age in place.

VasoDynamics is focused on developing cancer-preventative therapies aimed at enhancing cancer care. The company offers radioprotection programs that are backed by international patents and grounded in innovative research. These programs utilize affordable medications to help patients and healthcare professionals mitigate the common side effects associated with cancer treatments. By improving treatment outcomes and enhancing the quality of life for patients, VasoDynamics seeks to redefine standards in cancer care.

With modern science, we’ve come to realize that the secret to a fuller life is individual to each and every one of us. So what if you could wake up in the morning and before you’ve had your coffee or breakfast, your sidekick already knows how you are feeling – your energy levels, how you slept, how busy your day will be. What if it knew exactly what you needed to do to fill in missing nutrient gaps or give yourself the boost you need for your busy day? And you didn’t have to do anything yourself. What if you could achieve this by simply adjusting your morning breakfast order? Welcome to Healthy Longevity Café – a first of its kind integrated concept; combining highly accurate AI-powered data measurements (from behavioral assessments & medical tests) that serve as a guide for a personalized health plan (developed by healthcare professionals). We provide wellness guidance and serve you tasty superfoods infused with your daily dose of supplements and guarantee to give you exactly what your body needs. We are providing a Personalized Recipe for Longevity, available to everyone – globally. Healthy Longevity Café is a VC-backed company.

Healthy Longevity Guide is an educational platform for medical learning. They offer education, webinars, patient handouts, a marketplace, a catalog of medicine, courses, and certification.

We aspire to be a leading applied research organization in the field of advanced integrated and personalized therapies. With clinics in Europe and US, we work closely with research organizations to execute clinical trials and formulate advanced clinical programs.

The speed of research and product development is dramatically increasing. Most of that advancement is done by small, new companies - startups. These companies have no capacity to build worldwide distribution channels and the availability of their products is local and very limited. It is not even feasible for health professionals like physicians, clinics or specialized shops to buy directly, often oversee these emerging products. Diagnostic products mostly require sample collection or specialized laboratory preprocessing before shipping. We provide standardized or bespoke solutions for full selling life cycle of longevity products: - Market Research and Recommendations - Local Compliance - Local Brand Creation - Pre-contracted Local Distribution Channels or Direct Customers - Complete Logistics Solution - Sample Collection and Laboratory Processing

Celeris Therapeutics is an AI-driven drug discovery company focused on developing proximity-inducing compounds (PICs), particularly PIC degraders, to address diseases with significant unmet medical needs, including Parkinson's disease and various cancers. The company utilizes its proprietary Celeris One platform, which employs structure-based geometric deep learning to enhance the design and development of degraders. This platform aids in the prioritization of specific E3 ligases, the design of linkers, and the selection of the most promising compounds for synthesis. Additionally, Celeris Therapeutics operates an automated laboratory that rapidly generates experimental data for further optimization. The company collaborates with pharmaceutical and biotech firms to co-develop small-molecule degrader therapies across various therapeutic areas while also building its own drug pipeline. Celeris Therapeutics maintains offices in Menlo Park, California, and Graz, Austria.

Senisca is a biotech start-up. They propose to create a new generation of oligonucleotide-based interventions to rewind the clock in old cells and target diseases and cosmetic signs of aging. They provide molecular and cellular biology and have patent-protected an innovation for the reversal of cellular senescence.

GenFlow Biosciences is a preclinical biotechnology company that specializes in synthetic biology to develop gene therapies aimed at delaying or stopping the aging process in humans and canines. The company is dedicated to creating innovative biological interventions that target the effects of aging, with the goal of extending life expectancy and reducing the incidence of age-related diseases. By focusing on longevity and the development of treatments that address the challenges associated with advanced age, GenFlow Biosciences seeks to promote healthier, longer lives for both people and animals.

Yuva Biosciences specializes in developing cosmeceutical and pharmaceutical products aimed at addressing aging-related issues such as hair loss and skin wrinkles. The company focuses on restoring mitochondrial function, which is essential for cellular energy and health, to rejuvenate hair and skin. By leveraging mitochondrial science, Yuva Biosciences creates innovative solutions designed to counteract the symptoms of aging, enabling individuals to regain youthful vitality and appearance.

Sensable Health is a provider of health and wellness services focused on delivering a personalized approach to weight loss and overall well-being. The company offers an AI-driven mobile application that tailors programs to individual goals, unique biological factors, and specific lifestyle considerations. Users receive customized support and digital coaching, which aim to facilitate changes in their metabolic state and promote sustainable lifestyle modifications. Through this balanced and scientific method, Sensable Health strives to help individuals look better, feel better, and achieve long-term wellness.

Vesttoo Ltd is a financial technology company based in Tel Aviv, Israel, founded in 2018. It operates an artificial intelligence-driven platform that serves as a marketplace for non-catastrophe insurance-based risk transfer and investments. The platform enables the transfer of risk between insurance companies and institutional investors, providing innovative insurance-linked investment opportunities for asset managers. By facilitating risk transfer to the capital markets, Vesttoo offers insurers a cost-effective and efficient alternative to traditional reinsurance, with the capacity to handle a variety of Life and Property & Casualty insurance risks. Its proprietary AI technology streamlines processes such as deal structuring, risk modeling, and index calculation, while also enhancing liquidity in the insurance market. Vesttoo collaborates with industry leaders to create transparent and data-driven reinsurance transactions and has been recognized in various prestigious fintech accelerators. The company's team comprises professionals with expertise in financial engineering, technology, and risk management, further strengthening its position in the market.

Pano Therapeutics is a biotechnology company focused on developing small molecule drugs that target cellular energetics to address complex diseases, particularly those related to aging. The company specializes in creating treatments for rare and orphan diseases, as well as more prevalent chronic conditions, by utilizing their platform to discover biguanides and other compounds tailored for enhanced potency and selective tissue exposure. Their technology emphasizes the clinical development of drugs that interact with mitochondrial ion channels, aiming to improve therapeutic options for a variety of conditions, including kidney diseases and certain cancers, while also addressing disorders linked to metabolic dysfunction.

Mitrix bio is a mitochondrial dysfunction that has been implicated in chronic diseases such as Alzheimer’s, macular degeneration, immune senescence, liver and kidney dysfunction, cardiovascular disease, frailty, mitochondrial mutation diseases, and more.

Repair Biotechnologies, Inc. is a biotechnology company focused on developing innovative treatments aimed at reversing immunosenescence and atherosclerosis associated with aging. Founded in 2018 and based in Syracuse, New York, the company utilizes a cholesterol-degrading platform to create therapies that target conditions driven by excess or modified cholesterol, such as atherosclerosis and familial hypercholesterolemias. Through its gene therapy and recombinant protein approaches, Repair Biotechnologies seeks to address significant age-related health issues by treating the underlying causes of these medical conditions. The company's emphasis on safety and tolerability enhances its commitment to improving patient outcomes.

Yolife GmbH, founded in 2017 and based in Berlin, Germany, offers a mobile application focused on enhancing health through lifestyle changes, professional consultations, and medical therapies. The application is available on both the App Store and Google Play. Designed to help individuals add healthy years to their lives, Yolife’s app leverages insights from over 300 scientific studies to provide evidence-based lifestyle suggestions. It features an AI-driven approach that crafts personalized action plans for users, guiding them in fitness, nutrition, and wellness. Users can earn rewards for adhering to recommended diets, which also unlock deals from health-related products and services, thereby promoting overall health and well-being.

First Longevity provides daily news and insights on the fast-growing longevity market. They offer antiaging, biotech, research, investment, supplements, and rejuvenation therapies. They offer news under diverse categories including AI, nanotechnology, drugs, agritech, and investment, along with monetizing its contents through display advertisements.

Syd is a developer of predictive health technology aimed at enhancing life quality for organizations and their employees. The company offers a personalized AI companion that utilizes aggregated data and predictive analytics to provide tailored recommendations. By focusing on improving business outcomes, Syd helps increase productivity, enhance employee retention, and reduce absenteeism. This approach empowers organizations to optimize their talent strategies and foster a more engaged and satisfied workforce.

Life Biosciences focuses on developing drug therapies aimed at promoting longevity and treating age-related diseases. The company targets the eight pathways of age-related decline, addressing health issues from a systemic perspective rather than viewing them as isolated events. This comprehensive approach seeks to improve the quality of life for seniors, enabling them to better manage age-related conditions and ultimately extend their healthy life spans. By addressing the underlying mechanisms of aging, Life Biosciences aims to contribute significantly to advancements in geriatric health.

Animal Bioscience is focused on developing innovative products aimed at improving the health and longevity of animals, particularly pets and livestock. The company creates medical compounds and treatments that utilize advanced technologies to monitor physical activity and behavior in animals. These solutions are designed to alleviate aging symptoms and enhance the overall health span of animals. By addressing the needs of both pet and cattle owners, Animal Bioscience aims to facilitate better care for animals, ultimately contributing to their well-being and quality of life.

Nightingale Health is a health tech company focused on transforming preventive care through innovative blood-testing services. By providing deep health insights, the company enables individuals to understand their disease risk and the impact of lifestyle changes, which are often overlooked in standard lab tests. Its Health Data Platform connects healthcare services with individuals' preventive health needs, empowering them to take proactive measures to maintain their health. This approach not only fuels scientific discoveries and industry advancements but also encourages individuals to adopt healthier lifestyles.

AgeCurve is a company focused on healthy longevity, specializing in aging diagnostics and therapeutics. It has developed a platform that integrates single-cell genomics and transcriptomics to assess biological aging by quantifying thousands of human proteins. This technology allows AgeCurve to generate diagnostic reports for clinics, offering valuable insights into the aging process. Additionally, the platform aids in identifying drug repurposing candidates, thus contributing to advancements in aging therapeutics. Furthermore, it enhances the quality control of cell therapies, positioning AgeCurve as a key player in the field of longevity and age-related health solutions.

Gerostate Alpha is tackling human aging, an ambitious goal. The three co-founders are all academics at the Buck Institute where they’ve spent years researching aging. They’ve used their proprietary platform for drug discovery to quickly parse 90,000 compounds and identify 150 hits for further research.