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Klothea Bio is a protein well known for its powerful anti-aging capabilities, such as tumor suppression, neuroprotection, and antioxidative actions. As people age, their klotho levels drop to harmful levels. The metabolic disease syndrome will be the focus of the first investigations, while later studies will try to extend therapeutic applications to cancer, Alzheimer's disease, obesity, and other age-related diseases.

Yuva Biosciences is a company focused on restoring mitochondrial function to combat the effects of aging, particularly in hair and skin. It specializes in the development of cosmeceuticals and pharmaceuticals aimed at addressing issues such as aging-related hair loss, wrinkled skin, and diminished energy levels. By leveraging advancements in mitochondrial science, Yuva Biosciences creates products that aim to rejuvenate users, promoting healthier hair and skin while counteracting the visible signs of aging.

MitoRx Therapeutics is a biotechnology company focused on developing therapeutics that reverse mitochondrial dysfunction. It is developing small molecule therapies for weight loss with muscle preservation in obesity-related and cardiometabolic conditions. The company is advancing mitochondrial-targeted persulfide modifiers intended to restore a signaling mechanism identified in population studies. Preclinical data indicate efficacy against hepatosteatosis, potential as a monotherapy, and enhanced fat loss with lean mass gain when combined with glucagon-like peptide-1 receptor agonists.

Founded in 2016, Rejuvenation Technologies is a biotechnology company based in Mountain View, California. It specializes in developing nucleoside-modified TERT mRNA to safely extend telomeres for human health extension.

SiPhox Health, based in Cambridge, Massachusetts, specializes in designing and manufacturing innovative diagnostic solutions. The company develops next-generation diagnostics infrastructure, including at-home test kits and central lab systems. Their flagship product is a disposable biosensor cartridge that assesses 17 blood biomarkers, providing insights into inflammation, hormonal health, metabolic fitness, and cardiovascular health. SiPhox Health's platform merges biochemistry, photonic chip technology, integrated photonics, electronics, and microfluidics to enable sensitive readouts of immunoassays and nucleic acid tests, facilitating point-of-need and at-home diagnostics.

Cosmica Biosciences specializes in accelerating drug discovery for longevity by employing unbiased multi-scale biology coupled with machine learning algorithms. Its platform leverages data from human blood, organoids exposed to microgravity simulation and galactic radiation, as well as in vivo data from crew members and onboard experiments from NASA, SpaceX, and Axiom.

Cleara Biotech B.V. is a biotechnology company based in Utrecht, the Netherlands, focused on developing innovative therapeutics to selectively eliminate senescent and senescent-like cancer cells. The company specializes in creating FOXO4-based anti-senescence drugs aimed at addressing chemotoxicity and combating therapy-resistant cancer cells. Cleara Biotech's research targets a crucial aspect of cancer treatment by aiming to enhance the effectiveness of therapies and improve patient outcomes through the targeted removal of problematic cell populations.

Remedium Bio is a Boston-based gene therapy company dedicated to developing curative treatments for a variety of debilitating conditions. The company employs a unique approach that combines established technologies in innovative ways to address well-defined disease mechanisms. By modularly applying these proven technologies, Remedium Bio focuses on creating localized and targeted therapies centered on clinically validated molecules and pathways. Its pipeline includes leading gene therapy candidates in multiple fields, such as rheumatology, endocrinology, and neurology, aimed at providing effective treatments for a range of immune, age-related, and metabolic disorders.

Senisca is a senotherapeutics company established in 2020, focused on developing anti-aging oligonucleotide therapeutics. The company aims to provide innovative pharmaceutical treatments for age-related chronic diseases by creating a new generation of oligonucleotide-based interventions. These therapeutics target the underlying mechanisms of aging, restoring the ability of cells to regulate gene expression effectively. By rejuvenating aged cells, Senisca seeks to improve healthspan and address both the diseases and aesthetic manifestations of aging, ultimately enabling individuals to live healthier for longer periods.

MitoRx Therapeutics is a biotechnology company focused on developing therapeutics that reverse mitochondrial dysfunction. It is developing small molecule therapies for weight loss with muscle preservation in obesity-related and cardiometabolic conditions. The company is advancing mitochondrial-targeted persulfide modifiers intended to restore a signaling mechanism identified in population studies. Preclinical data indicate efficacy against hepatosteatosis, potential as a monotherapy, and enhanced fat loss with lean mass gain when combined with glucagon-like peptide-1 receptor agonists.

Sampling Human develops computational products to measure and analyze single-cell and spatial omic data at an industrial scale. Its technology enables pre-symptomatic screening, personalized medicine, drug discovery, and advancements in basic science.

Celeris Therapeutics is an AI-first drug discovery company that focuses on developing proximity-inducing compounds (PICs), particularly PIC degraders, to address high unmet medical needs in diseases like Parkinson's and various cancers. The company has created the Celeris One platform, which utilizes structure-based geometric deep learning to enhance the design and development of degraders by prioritizing specific E3 ligases, designing effective linkers, and selecting optimal compounds for synthesis. Additionally, Celeris Therapeutics operates an in-house automated laboratory that facilitates rapid generation of experimental data for further optimization. The company collaborates with pharmaceutical and biotech firms to discover and develop small-molecule degrader therapies across multiple therapeutic areas, while also advancing its own internal drug pipeline. Celeris Therapeutics maintains offices in Menlo Park, California, and Graz, Austria.

BrainKey is developing a digital therapeutics platform that analyzes vast amounts of brain data using AI-derived biomarkers. This enables more accurate diagnoses and personalized treatment recommendations for brain diseases, improving patient outcomes.

SiPhox Health, based in Cambridge, Massachusetts, specializes in designing and manufacturing innovative diagnostic solutions. The company develops next-generation diagnostics infrastructure, including at-home test kits and central lab systems. Their flagship product is a disposable biosensor cartridge that assesses 17 blood biomarkers, providing insights into inflammation, hormonal health, metabolic fitness, and cardiovascular health. SiPhox Health's platform merges biochemistry, photonic chip technology, integrated photonics, electronics, and microfluidics to enable sensitive readouts of immunoassays and nucleic acid tests, facilitating point-of-need and at-home diagnostics.

Collaborate Healthcare is a technology startup focused on enhancing clinical outcomes for pediatricians and general practitioners through innovative IT solutions. The company has developed a healthcare platform that includes patient relationship management (CRM) and collaboration tools, designed to transform medical care delivery into a technology-driven, patient-centered, team-based approach. By facilitating communication among medical practitioners, the platform allows for second opinions and helps to minimize diagnostic errors. It also supports seamless patient follow-up, ensuring that healthcare providers can deliver comprehensive care experiences.

Zoe Biosciences is developing a therapeutic platform focused on the apelin axis to target aging directly. This enables healthcare providers to potentially prevent or delay age-related chronic diseases.

Founded in 2016, Rejuvenation Technologies is a biotechnology company based in Mountain View, California. It specializes in developing nucleoside-modified TERT mRNA to safely extend telomeres for human health extension.

Cleara Biotech B.V. is a biotechnology company based in Utrecht, the Netherlands, focused on developing innovative therapeutics to selectively eliminate senescent and senescent-like cancer cells. The company specializes in creating FOXO4-based anti-senescence drugs aimed at addressing chemotoxicity and combating therapy-resistant cancer cells. Cleara Biotech's research targets a crucial aspect of cancer treatment by aiming to enhance the effectiveness of therapies and improve patient outcomes through the targeted removal of problematic cell populations.

Petri Bio is a biotechnology company focused on developing therapeutics derived from gut microbes. The company specializes in screening beneficial microbial genomes to identify and optimize useful compounds for healthcare applications. By harnessing the unique properties of these microbes, Petri Bio aims to enhance treatment options for various diseases, thereby enabling physicians to provide more effective care. Through its innovative approach, the company seeks to improve health outcomes by leveraging the potential of microbe-based products in medical treatments.

Maxwell Biosciences is a preclinical-stage company developing the CLAROMER biotechnology platform. This innovative platform creates low-molecular-weight compounds that mimic peptides and penetrate membranes easily, offering potential treatments for previously untreatable conditions.

Juvena Therapeutics is a biopharmaceutical company developing protein-based therapies to promote tissue rejuvenation and repair in elderly individuals. Founded in 2017, the company focuses on treating age-related conditions such as sarcopenia, wound healing, and neural regeneration.

Intervene Immune develops immunotherapies and diagnostics focused on thymus regeneration and age-related immune decline. By targeting thymic involution and epigenetic aging, it seeks to restore immune function in older adults, including methods that educate bone marrow-derived cells to differentiate into T cells that execute cellular immune responses against pathogens and tumors. The company aims to bolster protection against bacteria and viruses and to provide clinicians with tools for immune system regeneration in healthy elderly individuals.

NOVOS is a brand focused on longevity supplements, aiming to enhance users' lives through science-backed products designed to slow down aging processes. Their offerings include healthcare drinks enriched with anti-aging ingredients like nicotinamide riboside, magnesium, fisetin, and pterostilbene, along with antioxidants and other functional components that facilitate DNA repair and reduce damage, thereby potentially extending lifespan and improving overall health.

Founded in 2019, Occuity specializes in the research, design, and manufacture of non-contacting optical instruments for use in healthcare diagnostics and monitoring. The company develops a range of handheld meters that work by shining light into the eye and analyzing the return signal, enabling direct measurements for optometrists, ophthalmologists, and other healthcare professionals to monitor various conditions including diabetes and Alzheimer's disease.

Samsara Therapeutics, founded in 2018 with operations across Europe and San Diego, is a biopharmaceutical company dedicated to discovering and developing therapeutics for age-related diseases and unmet medical needs. Its proprietary platform focuses on identifying and validating compounds that extend healthy lifespan by targeting fundamental aging processes such as proteostasis and autophagy. The company aims to create novel treatments for rare genetic and neurodegenerative diseases through its pipeline, which involves compound identification, chemical optimization, and in vivo validation across various species.

Embrace Prevention Care is a healthcare service provider specializing in chronic illness management for elderly individuals. They offer regular consultations with nurse practitioners and pharmacists to monitor health conditions like heart failure. Their approach involves tracking patient progress across various aspects to identify potential issues early, aiming to prevent serious complications, reduce hospitalizations, and promote independent living.

Vasodynamics is a cancer-preventive therapy company focused on reducing treatment-related side effects and improving outcomes through radioprotection programs. Built on groundbreaking research and cost-efficient medicines, its programs are protected by international patents, enabling clinicians to prevent common complications of cancer therapy and enhance patients' quality of life.

The speed of research and product development is dramatically increasing. Most of that advancement is done by small, new companies - startups. These companies have no capacity to build worldwide distribution channels and the availability of their products is local and very limited. It is not even feasible for health professionals like physicians, clinics or specialized shops to buy directly, often oversee these emerging products. Diagnostic products mostly require sample collection or specialized laboratory preprocessing before shipping. We provide standardized or bespoke solutions for full selling life cycle of longevity products: - Market Research and Recommendations - Local Compliance - Local Brand Creation - Pre-contracted Local Distribution Channels or Direct Customers - Complete Logistics Solution - Sample Collection and Laboratory Processing

With modern science, we’ve come to realize that the secret to a fuller life is individual to each and every one of us. So what if you could wake up in the morning and before you’ve had your coffee or breakfast, your sidekick already knows how you are feeling – your energy levels, how you slept, how busy your day will be. What if it knew exactly what you needed to do to fill in missing nutrient gaps or give yourself the boost you need for your busy day? And you didn’t have to do anything yourself. What if you could achieve this by simply adjusting your morning breakfast order? Welcome to Healthy Longevity Café – a first of its kind integrated concept; combining highly accurate AI-powered data measurements (from behavioral assessments & medical tests) that serve as a guide for a personalized health plan (developed by healthcare professionals). We provide wellness guidance and serve you tasty superfoods infused with your daily dose of supplements and guarantee to give you exactly what your body needs. We are providing a Personalized Recipe for Longevity, available to everyone – globally. Healthy Longevity Café is a VC-backed company.

Healthy Longevity Guide is an educational platform for medical learning. They offer education, webinars, patient handouts, a marketplace, a catalog of medicine, courses, and certification.

We aspire to be a leading applied research organization in the field of advanced integrated and personalized therapies. With clinics in Europe and US, we work closely with research organizations to execute clinical trials and formulate advanced clinical programs.

Celeris Therapeutics is an AI-first drug discovery company that focuses on developing proximity-inducing compounds (PICs), particularly PIC degraders, to address high unmet medical needs in diseases like Parkinson's and various cancers. The company has created the Celeris One platform, which utilizes structure-based geometric deep learning to enhance the design and development of degraders by prioritizing specific E3 ligases, designing effective linkers, and selecting optimal compounds for synthesis. Additionally, Celeris Therapeutics operates an in-house automated laboratory that facilitates rapid generation of experimental data for further optimization. The company collaborates with pharmaceutical and biotech firms to discover and develop small-molecule degrader therapies across multiple therapeutic areas, while also advancing its own internal drug pipeline. Celeris Therapeutics maintains offices in Menlo Park, California, and Graz, Austria.

Senisca is a senotherapeutics company established in 2020, focused on developing anti-aging oligonucleotide therapeutics. The company aims to provide innovative pharmaceutical treatments for age-related chronic diseases by creating a new generation of oligonucleotide-based interventions. These therapeutics target the underlying mechanisms of aging, restoring the ability of cells to regulate gene expression effectively. By rejuvenating aged cells, Senisca seeks to improve healthspan and address both the diseases and aesthetic manifestations of aging, ultimately enabling individuals to live healthier for longer periods.

Yuva Biosciences is a company focused on restoring mitochondrial function to combat the effects of aging, particularly in hair and skin. It specializes in the development of cosmeceuticals and pharmaceuticals aimed at addressing issues such as aging-related hair loss, wrinkled skin, and diminished energy levels. By leveraging advancements in mitochondrial science, Yuva Biosciences creates products that aim to rejuvenate users, promoting healthier hair and skin while counteracting the visible signs of aging.

GenFlow Biosciences is a biotechnology company developing therapies to counteract aging. It focuses on preclinical programs that aim to slow or halt aging processes and reduce age-related diseases by applying synthetic biology and gene therapy approaches. The company pursues interventions intended to extend life expectancy and healthspan in humans and companion animals, including canines, through therapies designed to mitigate diseases associated with aging.

Sensable Health operates a health and wellness application that provides personalized, science-based programs for sustainable weight loss and long-term well-being. It considers individual goals, unique biology, lifestyle factors, offering customized support and digital coaching.

Vesttoo Ltd is a Tel Aviv-based company that operates an artificial intelligence-driven financial risk management platform. Established in 2018, Vesttoo focuses on creating a marketplace for non-catastrophic insurance-based risk transfer and investments, connecting insurance companies with institutional investors. Its proprietary technology enhances risk transfer and liquidity in the life and property & casualty insurance markets by facilitating faster deal structuring, risk modeling, pricing, and index calculation. Vesttoo provides a range of solutions that cater to the legal, regulatory, and accounting needs of its clients, which include insurers, reinsurers, and pension funds. By offering asset managers access to diverse, uncorrelated investment options linked to insurance and reinsurance premiums, the company positions itself as a significant alternative to traditional reinsurance models. Vesttoo's innovation has garnered recognition through participation in prestigious fintech accelerators and collaborations with industry leaders, further establishing its role in merging insurance with capital market dynamics.

Pano Therapeutics is a biotechnology company focused on the development of small molecule drugs aimed at treating rare and prevalent chronic diseases, particularly those related to aging and metabolic dysfunction. The company's innovative platform is designed to discover biguanides and other compounds that target mitochondrial ion channels and organic cation transporters, enhancing drug potency and selective tissue exposure. Pano Therapeutics is engaged in the clinical development of therapies for complex disease states, including various cancers and kidney diseases, leveraging its preclinical assets to provide improved treatment options for a diverse range of health conditions. Through its research, the company aims to advance the understanding and treatment of diseases associated with cellular energetics.

Mitrix bio is a mitochondrial dysfunction that has been implicated in chronic diseases such as Alzheimer’s, macular degeneration, immune senescence, liver and kidney dysfunction, cardiovascular disease, frailty, mitochondrial mutation diseases, and more.

Repair Biotechnologies, Inc. is a biotechnology company founded in 2018 and based in Syracuse, New York. The company focuses on developing innovative therapies aimed at reversing the progression of age-related conditions such as immunosenescence and atherosclerosis. Utilizing a cholesterol-degrading platform, Repair Biotechnologies creates treatments that address conditions driven by excess or modified cholesterol, including atherosclerosis and familial hypercholesterolemia. Their approach centers on gene therapy and recombinant protein strategies, designed to be safe and well-tolerated, allowing patients to target the underlying causes of diseases associated with cholesterol accumulation.

Yolife GmbH is a Berlin-based company founded in 2017 that develops a mobile application aimed at promoting good health through lifestyle changes, professional consultations, and medical therapies. The app, available on both the App Store and Google Play, leverages insights from over 300 scientific studies to provide users with personalized fitness, nutrition, and wellness guidance. Yolife's mission is to help one billion people add 15 healthy years to their lives by making life-extending practices easy and accessible. Users can create custom action plans, earn rewards for adhering to dietary recommendations, and unlock deals from health product and service providers, all while enhancing their overall health and longevity.

First Longevity provides daily news and insights on the fast-growing longevity market. They offer antiaging, biotech, research, investment, supplements, and rejuvenation therapies. They offer news under diverse categories including AI, nanotechnology, drugs, agritech, and investment, along with monetizing its contents through display advertisements.

Developer of AI-driven solutions that empower various industries such as government, insurance, corporations, education, healthcare, and pharma. SYD's technology provides personalized AI companions that deliver data-driven recommendations within enterprises to enhance business outcomes, productivity, retention, and reduce absenteeism.

Life Biosciences is a biotechnology company focused on developing drug therapies aimed at promoting longevity and treating age-related diseases. The company's approach addresses the systemic breakdown of the body due to aging, targeting the eight pathways of age-related decline. By considering health decline as an interconnected process rather than a collection of isolated issues, Life Biosciences seeks to empower senior citizens to combat various age-related conditions, ultimately striving to extend healthy life spans.

Animal Bioscience is a company focused on developing innovative products aimed at enhancing the health and longevity of animals, particularly pets and cattle. The firm specializes in creating medical compounds and treatments that utilize advanced technologies to monitor physical activity and behavior in animals. By addressing the symptoms of aging, Animal Bioscience seeks to prolong the youth and expand the lifespan of animals, thereby improving overall well-being for pet and livestock owners.

Nightingale Health is a global health technology company dedicated to transforming preventive care through innovative blood-testing services. By providing comprehensive health insights, it enables individuals to identify disease risks and assess the impact of lifestyle changes that standard lab tests may overlook. The company's Health Data Platform connects healthcare providers with the preventative health needs of individuals, fostering informed decision-making and encouraging proactive health management. Nightingale Health's approach emphasizes the importance of maintaining health rather than merely addressing illnesses, ultimately contributing to scientific advancements and promoting positive lifestyle changes among users.

AgeCurve is a company that develops a healthy longevity platform combining single‑cell genomics and transcriptomics for aging diagnostics and therapeutics. It offers kit sequences and quantifies thousands of human proteins to assess aspects of biological aging. The platform generates diagnostic reports for clinics and provides insights into drug repurposing candidates, enabling advancements in aging therapeutics and cell therapy quality control.

Founded in 2018 by academic researchers from the Buck Institute, Gerostate Alpha is a biopharmaceutical company dedicated to developing treatments for aging and age-related diseases. Utilizing its proprietary drug discovery platform, the company aims to extend healthspan and lifespan.