Avidicure
Seed Round in 2025
Avidicure is a cancer care company focused on enhancing immune system performance through innovative therapeutic approaches. The company is developing a novel class of antibodies known as AVC-Boosters, which are engineered to act as dual agonists. This multifunctional modality aims to deliver targeted and effective monotherapy, offering broad applicability in oncology. Currently operating in stealth mode, Avidicure is dedicated to pioneering advancements in cancer treatment that prioritize safety and efficacy.
Perfuze
Venture Round in 2025
Perfuze is a neurovascular medical device company based in Galway, Ireland, founded in 2018. The company focuses on developing innovative catheter technology specifically for the treatment of acute ischemic stroke. Perfuze aims to enhance clinical outcomes and reduce procedural times through its proprietary catheter-based aspiration technology, which optimizes the efficiency of clot removal. By simplifying procedures and minimizing the need for alternative treatment methods, Perfuze seeks to provide cost-effective solutions for patients suffering from ischemic stroke.
Cornerstone Robotics
Series C in 2025
Cornerstone Robotics is a company dedicated to enhancing the accessibility of advanced medical services in China through the development of innovative medical robotic devices. Its primary focus lies in creating a safe and efficient surgical robotics platform that empowers physicians to perform surgeries with greater accuracy and efficiency. By investing in research and development, Cornerstone Robotics aims to advance the field of surgical robotics, thereby improving patient outcomes and transforming surgical practices.
XyloCor Therapeutics
Series B in 2025
XyloCor Therapeutics, Inc. is a biopharmaceutical company specializing in the development of gene therapies for cardiovascular diseases, particularly advanced coronary artery disease. Founded in 2013 and based in Newtown Square, Pennsylvania, the company focuses on innovative treatments aimed at addressing significant unmet medical needs. Its lead product candidate, XC001, is currently in clinical development for patients suffering from refractory angina, targeting individuals who have exhausted other treatment options. XyloCor's approach centers on stimulating the formation of new coronary blood vessels to enhance blood supply to areas of the heart that are inadequately perfused, thereby improving patient outcomes in those affected by heart failure and ischemic conditions. The company collaborates with Weill Cornell Medical College to advance its gene therapy technologies.
Noema Pharma
Series B in 2024
Noema Pharma AG is a biotechnology company based in Basel, Switzerland, founded in 2019. The company focuses on developing innovative therapeutic products for orphan neurological disorders characterized by imbalanced neuronal networks. Its research and development efforts are dedicated to addressing disabling symptoms associated with conditions affecting the nervous system, such as Tuberous Sclerosis Complex, Trigeminal Neuralgia, and Tourette syndrome. By creating novel therapies, Noema Pharma aims to enhance the quality of life and improve patient outcomes for those suffering from these challenging disorders.
Tenpoint Therapeutics
Venture Round in 2024
Tenpoint Therapeutics is a biotechnology company dedicated to developing engineered cell-based therapies aimed at restoring vision for individuals affected by degenerative ocular diseases. The company leverages an innovative platform that includes in vivo reprogramming techniques, allowing for targeted delivery of therapeutic systems directly to the eye. This approach eliminates the need for systemic administration, which can improve treatment efficacy and patient outcomes. By focusing on vision restoration, Tenpoint Therapeutics strives to significantly enhance the quality of life for patients suffering from various eye conditions.
NUA Surgical
Series A in 2024
NUA Surgical is an award-winning startup based at the Innovation Hub in Galway, Ireland. The company has developed a patented surgical retractor designed to enhance the safety and efficiency of C-section procedures. NUA Surgical focuses on creating innovative medical devices for women's health, with a particular emphasis on improving outcomes for cesarean deliveries.
ATB Therapeutics
Series A in 2024
ATB Therapeutics is a biopharmaceutical company that provides novel therapeutic solutions and treatments for cancer patients.
GeBBS Healthcare Solutions
Acquisition in 2024
GeBBS Healthcare Solutions is a technology-enabled company that provides revenue cycle management (RCM) solutions to improve financial performance, compliance, and patient satisfaction. Founded in 2005 and headquartered in Culver City, California, GeBBS offers a range of services including Health Information Management (HIM), Revenue Cycle Management (RCM), Patient Access, Risk Adjustment Solutions, strategic outsourcing, and consulting services. The company serves hospitals, physician groups, health plans, and medical billing companies. With over 6,000 employees globally, GeBBS has formed strategic partnerships with various industry associations and organizations.
Asceneuron
Series C in 2024
Asceneuron SA, established in 2012 and headquartered in Lausanne, Switzerland, is a biotechnology subsidiary of Merck KGaA dedicated to discovering and developing therapeutics for neurodegenerative disorders with high unmet medical needs. The company focuses on progressive supranuclear palsy, orphan tauopathies, Alzheimer's disease, and Parkinson's disease, aiming to provide effective treatments where none currently exist or are limited in their benefits. Asceneuron operates by targeting the underlying causes of these debilitating conditions, such as abnormal tau protein deposits, with the goal of developing orally bioavailable therapeutics that can improve patients' lives and address the growing healthcare burden posed by neurodegenerative diseases.
Vico Therapeutics
Series B in 2024
Vico Therapeutics B.V. is a biotechnology company based in Leiden, the Netherlands, founded in 2019. The company specializes in the development of RNA modulating therapies aimed at treating rare neurological disorders. Vico Therapeutics focuses on conditions such as spinocerebellar ataxias, Huntington’s disease, and Rett syndrome, which encompass a range of hereditary and neurodevelopmental disorders. By discovering and developing innovative therapies, the company aims to address significant unmet medical needs in the central nervous system, providing new treatment options for patients and healthcare professionals.
Onward is a medical technology company focused on developing therapies aimed at enabling functional recovery for individuals with spinal cord injuries. The company is creating an Implantable Neuro-stimulation System (INS) that features real-time motion feedback and utilizes training tools for rehabilitation. Onward has developed two platforms for neurostimulation: ARCIM, an implantable system, and ARCEX, a non-invasive transcutaneous system. To establish its customer base, Onward has targeted the United States and four European markets, namely Germany, France, the United Kingdom, and the Netherlands.
Tubulis GmbH, founded in 2019 and based in Munich, Germany, specializes in the research, design, and development of protein-drug conjugates, particularly focusing on antibody-drug conjugates (ADCs). The company aims to create transformative chemotherapeutic medications that are tailored to combat cancer and chronic diseases. By integrating proprietary technologies with disease-specific biology, Tubulis develops unique protein-drug combinations that enable clinicians to treat patients while minimizing the adverse effects typically associated with traditional chemotherapy. Through its innovative approach, Tubulis seeks to improve therapeutic outcomes and enhance the safety of cancer treatments.
Vico Therapeutics
Series B in 2024
Vico Therapeutics B.V. is a biotechnology company based in Leiden, the Netherlands, founded in 2019. The company specializes in the development of RNA modulating therapies aimed at treating rare neurological disorders. Vico Therapeutics focuses on conditions such as spinocerebellar ataxias, Huntington’s disease, and Rett syndrome, which encompass a range of hereditary and neurodevelopmental disorders. By discovering and developing innovative therapies, the company aims to address significant unmet medical needs in the central nervous system, providing new treatment options for patients and healthcare professionals.
LUMA Vision
Series A in 2023
LUMA Vision is a company focused on developing connected intra-vascular medical devices to enhance the treatment of cardiac arrhythmias. Utilizing advanced four-dimensional imaging and artificial intelligence, LUMA Vision improves the efficacy of electrophysiology (EP) and structural heart interventions. The company's innovative approach enables healthcare professionals to conduct cardiac procedures that lead to better patient outcomes, increased procedural safety, and lower costs for the healthcare system. Through real-time tissue analysis, LUMA Vision is poised to transform how cardiac treatments are performed, ultimately benefiting both patients and healthcare providers.
Shinobi Therapeutics
Series A in 2023
Shinobi Therapeutics is a biotechnology company dedicated to developing innovative cell therapies that utilize hypoimmune CD8αβ induced pluripotent stem cells (iPS-T cells) to enhance cancer treatment and address other diseases. The company's advanced immune evasion technology aims to improve the effectiveness and accessibility of these therapies, ultimately reducing costs and enhancing patient outcomes. By focusing on durable responses and the potential for redosing, Shinobi Therapeutics strives to provide the healthcare industry with comprehensive immune therapies that can address a range of diseases, including cancer and genetic disorders.
Nouscom is a biotechnology company focused on developing an immunotherapy platform that creates engineered viral vector vaccines for cancer treatment. The company's innovative platform leverages a portfolio of modified viral vectors, specifically designed for the efficient expression of long strings of tumor neoantigens. This approach is complemented by a toolkit that facilitates the induction of robust antitumor T-cell responses, effectively enhancing cancer-specific cellular immunity in patients. Through its research and development efforts, Nouscom aims to improve cancer treatment outcomes by harnessing the body's immune system to target and combat cancer cells.
MinervaX
Venture Round in 2023
MinervaX is a biotechnology company focused on developing maternal vaccines to prevent infections caused by Group B streptococcus (GBS), which can lead to serious adverse pregnancy outcomes and life-threatening conditions for newborns. The company leverages a specific fusion protein that has shown promise in eliciting protective immunity against various clinically relevant GBS strains. By concentrating on this innovative vaccine approach, MinervaX aims to provide medical professionals with effective tools to safeguard newborns from bacterial infections, ultimately enhancing maternal and infant health outcomes.
AstronauTx
Series A in 2023
AstronauTx is a biotechnology company focused on developing innovative treatments for Alzheimer's disease and other neurodegenerative conditions. The company specializes in restoring the normal function of astrocytes, which are crucial for supporting neuronal activity and maintaining brain health. In healthy individuals, astrocytes play a vital role in metabolism and the integrity of the blood-brain barrier; however, in neurodegenerative diseases, their dysfunction can contribute to neurotoxicity. By targeting these processes, AstronauTx aims to enable healthcare professionals to more effectively address the challenges posed by dementias, ultimately improving patient outcomes.
Evommune, Inc. is a biotechnology company based in Los Altos, California, that develops and manufactures tissue-based medicines for inflammatory diseases. Incorporated in 2020, Evommune focuses on creating novel strategies to treat these disorders by addressing both symptoms and the underlying causes, thereby halting disease progression. The company employs a proprietary tissue-based platform that accelerates the discovery of innovative treatments, enhancing the potential for clinical success. With a commitment to improving the quality of life for patients, Evommune's pipeline includes initiatives aimed at tackling a range of prevalent inflammatory illnesses, positioning the company as a leader in advancing therapies in the fields of immunology and dermatology.
QurAlis Corporation is a clinical-stage biotechnology company focused on discovering and developing therapeutics for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. Established in 2016 and based in Cambridge, Massachusetts, QurAlis employs proprietary platforms and biomarkers to create precision medicines that target genetically validated disease-causing alterations. The company’s pipeline includes innovative treatments aimed at specific subtypes of ALS, such as therapies that restore dysfunctional cellular waste clearance, manage overactive neurons, and eliminate toxic proteins. Through its advanced antisense oligonucleotides and small molecule programs, QurAlis seeks to halt disease progression and significantly improve patient outcomes for those affected by ALS.
FundamentalVR
Series B in 2022
FundamentalVR have been working with leading pharmaceutical companies to combine virtual and mixed reality with haptic feedback using their ‘FeelRealVR’ platform to create simulated surgical procedures to help educate and train healthcare professionals. The company works at the nexus of haptics, machine learning, and immersive technologies (XR). FundamentalVR was established in 2012 by Chris Scattergood in London, England.
Xilis, Inc. is a biotechnology company founded in 2019 and based in Chapel Hill, North Carolina. The company specializes in developing next-generation organoid technologies aimed at guiding precision therapy for cancer patients and enhancing drug discovery processes. Its flagship platform, XilisµO, facilitates rapid diagnostics, personalized drug screening, and the creation of scalable patient-derived models, which support high-throughput drug discovery. By enabling both physicians and pharmaceutical companies to conduct tailored drug screenings, Xilis aims to lower costs and improve treatment outcomes for cancer patients.
Ariceum Therapeutics
Series A in 2022
Ariceum Therapeutics is a clinical-stage radiopharmaceutical company that focuses on the detection and targeted treatment of aggressive cancers, particularly neuroendocrine tumors and other challenging malignancies. The company's lead product, 177Lu-satoreotide tetraxetan (Satoreotide), acts as an antagonist of the somatostatin type 2 receptor (SSTR2), which is commonly overexpressed in many neuroendocrine tumors. Ariceum is developing Satoreotide as a theranostic pair, which allows for both the diagnosis and targeted radionuclide treatment of neuroendocrine malignancies, certain aggressive tumors, and childhood cancers. This approach aims to provide treatment options for conditions that currently have limited therapies and poor prognoses, enabling healthcare professionals to deliver more effective treatments with reduced side effects.
Perfuze is a neurovascular medical device company based in Galway, Ireland, founded in 2018. The company focuses on developing innovative catheter technology specifically for the treatment of acute ischemic stroke. Perfuze aims to enhance clinical outcomes and reduce procedural times through its proprietary catheter-based aspiration technology, which optimizes the efficiency of clot removal. By simplifying procedures and minimizing the need for alternative treatment methods, Perfuze seeks to provide cost-effective solutions for patients suffering from ischemic stroke.
ViCentra B.V., based in Utrecht, the Netherlands, specializes in the development of medical devices, particularly for diabetes management. The company focuses on creating user-friendly and aesthetically pleasing products that aim to enhance the overall experience for individuals managing their health. ViCentra emphasizes the importance of excellent customer experiences and approaches product design with the belief that simplicity and effectiveness lead to better health outcomes. In addition to its operations in the Netherlands, ViCentra also has a presence in the UK, where it continues to innovate in the field of medical devices through dedicated research and development efforts.
3Shape
Private Equity Round in 2021
3Shape is a global leader in digital dentistry, specializing in advanced intraoral scanning solutions and software for computer-aided design (CAD) and computer-aided manufacturing (CAM). The company offers a comprehensive range of products, including 3D scanners, lab scanners, and cone-beam computed tomography (CT) scanners, which serve both dental and audio industries. With its innovative technology, 3Shape enables dental and hearing professionals to enhance treatment planning and visualization, thereby improving patient care and efficiency. Operating in over 100 countries, the company is committed to providing state-of-the-art solutions that empower practitioners to deliver superior results.
AviadoBio
Series A in 2021
AviadoBio is a biotechnology company focused on developing transformative gene therapies for neurodegenerative disorders, specifically targeting diseases such as frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). The company leverages innovative research from King’s College London and the UK Dementia Research Institute to create its therapeutic platform. By integrating a deep understanding of brain biology with proprietary gene therapies, AviadoBio aims to effectively address the challenges of delivering treatments to the appropriate areas within the nervous system. The ultimate goal is to enhance the therapeutic potential of gene therapy, potentially halting or even reversing the progression of these debilitating conditions, thereby improving the quality of life for affected individuals.
Icon Group
Acquisition in 2021
Icon Group is a global provider of cancer care services, focusing on delivering comprehensive care to patients at accessible locations. The company offers a range of services including medical and radiation oncology, hematology, health screening, pharmacy, chemotherapy, and compounding. By aiming to enhance the quality of care available, Icon Group ensures that patients receive tailored treatment options close to their homes, thereby improving the overall patient experience in cancer care.
DNA Script
Series C in 2021
DNA Script is a pioneering company in the field of DNA synthesis, focused on enhancing life sciences and human health through innovative technology. It has developed the SYNTAX, the world's first benchtop DNA printer, which allows laboratories to produce synthetic oligonucleotides using a novel enzymatic process. This method employs natural enzymes for nucleic acid synthesis, enabling rapid and efficient production of critical genomic experimental precursors. By providing greater control over workflow and accelerating access to results, DNA Script supports researchers in advancing experiments and developing new therapeutics effectively.
Egle Therapeutics
Series A in 2021
Egle Therapeutics SAS is a biotechnology company founded in 2020 and based in Paris, France. The company specializes in developing immunotherapies aimed at targeting immune suppressor regulatory T-cells (Tregs) to address oncology and autoimmune diseases. Egle Therapeutics is focused on its proprietary pipeline, which includes a series of computationally designed IL-2 variants designed to modulate Tregs by either engaging or disengaging them from tumor environments. Through its innovative approach to Treg modulation, the company aims to enable healthcare professionals to develop new therapies that effectively target these immune suppressor cells, potentially transforming treatment options for cancer and other diseases.
LUMA Vision
Series A in 2021
LUMA Vision is a company focused on developing connected intra-vascular medical devices to enhance the treatment of cardiac arrhythmias. Utilizing advanced four-dimensional imaging and artificial intelligence, LUMA Vision improves the efficacy of electrophysiology (EP) and structural heart interventions. The company's innovative approach enables healthcare professionals to conduct cardiac procedures that lead to better patient outcomes, increased procedural safety, and lower costs for the healthcare system. Through real-time tissue analysis, LUMA Vision is poised to transform how cardiac treatments are performed, ultimately benefiting both patients and healthcare providers.
Evommune, Inc. is a biotechnology company based in Los Altos, California, that develops and manufactures tissue-based medicines for inflammatory diseases. Incorporated in 2020, Evommune focuses on creating novel strategies to treat these disorders by addressing both symptoms and the underlying causes, thereby halting disease progression. The company employs a proprietary tissue-based platform that accelerates the discovery of innovative treatments, enhancing the potential for clinical success. With a commitment to improving the quality of life for patients, Evommune's pipeline includes initiatives aimed at tackling a range of prevalent inflammatory illnesses, positioning the company as a leader in advancing therapies in the fields of immunology and dermatology.
Visus Therapeutics
Debt Financing in 2021
Visus Therapeutics is a clinical-stage company focused on developing innovative ophthalmic therapies aimed at enhancing vision for individuals worldwide. The company is known for its presbyopia-correcting eye drops, which are designed to provide a prolonged solution to the loss of near vision associated with presbyopia. In addition to these eye drops, Visus Therapeutics is exploring various ophthalmic product candidates that address conditions such as ocular surface disease, glaucoma, and age-related macular degeneration, thereby broadening its impact on eye health and vision improvement.
Blikk Holding
Acquisition in 2021
The blikk group is a growing network of radiological, nuclear medicine and nephrology practices using dialysis. As a reliable partner for patients and referring physicians, the practices of the association make a significant contribution to high-quality medical care. They all share the common claim to the highest quality and excellent education and training of medical and non-medical staff in all disciplines.
Muna Therapeutics
Series A in 2021
Muna Therapeutics is a private biopharmaceutical company focused on discovering and developing therapies aimed at slowing or halting the progression of neurodegenerative diseases such as Parkinson's, Alzheimer's, Frontotemporal Dementia, and Multiple Sclerosis. The company is dedicated to identifying innovative medicines that preserve cognitive functions and enhance resilience in individuals affected by these conditions. By prioritizing the development of suitable therapeutics, Muna Therapeutics aims to improve recovery outcomes for patients suffering from neurodegenerative diseases.
Meine Radiologie Holding
Acquisition in 2021
Meine Radiologie Holding GmbH is a provider of radiological and radiotherapy treatment services focused on imaging diagnostics. The company specializes in offering radiology diagnostics and radiation treatments for both malignant and benign conditions. Additionally, it supports radiological and nuclear medicine practices by acting as a financial investor and professional management partner, particularly in succession planning. Through its services, Meine Radiologie Holding aims to create added value for doctors, employees, referrers, and patients by optimizing both central and local processes within the healthcare framework.
Xilis, Inc. is a biotechnology company founded in 2019 and based in Chapel Hill, North Carolina. The company specializes in developing next-generation organoid technologies aimed at guiding precision therapy for cancer patients and enhancing drug discovery processes. Its flagship platform, XilisµO, facilitates rapid diagnostics, personalized drug screening, and the creation of scalable patient-derived models, which support high-throughput drug discovery. By enabling both physicians and pharmaceutical companies to conduct tailored drug screenings, Xilis aims to lower costs and improve treatment outcomes for cancer patients.
Onward
Venture Round in 2021
Onward is a medical technology company focused on developing therapies aimed at enabling functional recovery for individuals with spinal cord injuries. The company is creating an Implantable Neuro-stimulation System (INS) that features real-time motion feedback and utilizes training tools for rehabilitation. Onward has developed two platforms for neurostimulation: ARCIM, an implantable system, and ARCEX, a non-invasive transcutaneous system. To establish its customer base, Onward has targeted the United States and four European markets, namely Germany, France, the United Kingdom, and the Netherlands.
Cerba HealthCare S.A.S.
Acquisition in 2021
Cerba HealthCare S.A.S. is a clinical pathology laboratory that offers a range of routine and specialized laboratory testing services. The company operates a network of medical laboratories that serve a diverse clientele, including private patients, physicians, hospitals, retirement and nursing homes, as well as pharmaceutical and biotech companies. Cerba HealthCare focuses on both standard laboratory tests and more complex specialty testing, enabling clients to interpret and analyze test results effectively. This comprehensive approach aids in the monitoring of patient health and provides significant insights based on clinical context, enhancing the decision-making process for healthcare providers.
Neurent Medical
Series B in 2021
Neurent Medical Limited is a medical device company based in Galway, Ireland, founded in 2015 by Brian Shields and David Townley. The company specializes in developing non-surgical treatments for inflammatory sino-nasal diseases, specifically focusing on chronic rhinitis. Neurent Medical offers a single-use, minimally invasive device designed for ENT surgeons, which utilizes a hand-held radio-frequency mechanism. This device is introduced through the nostrils into the nasal cavity under direct endoscopic visualization, where it deploys a microelectrode array to deliver targeted energy. This intervention interrupts the autonomic function of the mucosal structures in the nasal cavities, effectively reversing the inflammatory cascade. By enabling treatment in an office setting, Neurent Medical aims to eliminate the complications and costs typically associated with traditional surgical procedures for rhinitis.
XyloCor Therapeutics
Venture Round in 2021
XyloCor Therapeutics, Inc. is a biopharmaceutical company specializing in the development of gene therapies for cardiovascular diseases, particularly advanced coronary artery disease. Founded in 2013 and based in Newtown Square, Pennsylvania, the company focuses on innovative treatments aimed at addressing significant unmet medical needs. Its lead product candidate, XC001, is currently in clinical development for patients suffering from refractory angina, targeting individuals who have exhausted other treatment options. XyloCor's approach centers on stimulating the formation of new coronary blood vessels to enhance blood supply to areas of the heart that are inadequately perfused, thereby improving patient outcomes in those affected by heart failure and ischemic conditions. The company collaborates with Weill Cornell Medical College to advance its gene therapy technologies.
Lumeon Ltd. is a digital health company based in London, United Kingdom, specializing in care pathway management solutions for the healthcare sector. Founded in 2005 and previously known as Qinec Ltd., Lumeon offers a cloud-based platform called Care Pathway Manager, which provides a comprehensive, real-time view of the patient journey from referral to outcome. The platform enables healthcare providers to unify clinical and administrative workflows, automate tasks, and deliver measurable care, addressing the underlying systems that drive healthcare transformation. Lumeon's clientele includes some of Europe's leading healthcare providers, such as BUPA and Nuffield Health, reflecting its position as a key player in the market. The company employs over 90 professionals dedicated to enhancing patient care through effective management and analysis of healthcare pathways.
DNA Script
Series B in 2020
DNA Script is a pioneering company in the field of DNA synthesis, focused on enhancing life sciences and human health through innovative technology. It has developed the SYNTAX, the world's first benchtop DNA printer, which allows laboratories to produce synthetic oligonucleotides using a novel enzymatic process. This method employs natural enzymes for nucleic acid synthesis, enabling rapid and efficient production of critical genomic experimental precursors. By providing greater control over workflow and accelerating access to results, DNA Script supports researchers in advancing experiments and developing new therapeutics effectively.
Vico Therapeutics
Series A in 2020
Vico Therapeutics B.V. is a biotechnology company based in Leiden, the Netherlands, founded in 2019. The company specializes in the development of RNA modulating therapies aimed at treating rare neurological disorders. Vico Therapeutics focuses on conditions such as spinocerebellar ataxias, Huntington’s disease, and Rett syndrome, which encompass a range of hereditary and neurodevelopmental disorders. By discovering and developing innovative therapies, the company aims to address significant unmet medical needs in the central nervous system, providing new treatment options for patients and healthcare professionals.
ViCentra
Venture Round in 2020
ViCentra B.V., based in Utrecht, the Netherlands, specializes in the development of medical devices, particularly for diabetes management. The company focuses on creating user-friendly and aesthetically pleasing products that aim to enhance the overall experience for individuals managing their health. ViCentra emphasizes the importance of excellent customer experiences and approaches product design with the belief that simplicity and effectiveness lead to better health outcomes. In addition to its operations in the Netherlands, ViCentra also has a presence in the UK, where it continues to innovate in the field of medical devices through dedicated research and development efforts.
Cybin is a biopharmaceutical company dedicated to advancing research and development in psychedelic and medicinal mushrooms. It focuses on creating safe and effective therapeutics for mental health issues, with an emphasis on psilocybin-based products. The company is actively launching these products in jurisdictions where they are permitted and is engaged in clinical studies across North America and other regions. Through strategic partnerships with academic and institutional entities, Cybin seeks to develop novel compounds and delivery mechanisms, aiming to provide innovative treatments for various psychiatric and neurological conditions.
LUMA Vision
Series A in 2020
LUMA Vision is a company focused on developing connected intra-vascular medical devices to enhance the treatment of cardiac arrhythmias. Utilizing advanced four-dimensional imaging and artificial intelligence, LUMA Vision improves the efficacy of electrophysiology (EP) and structural heart interventions. The company's innovative approach enables healthcare professionals to conduct cardiac procedures that lead to better patient outcomes, increased procedural safety, and lower costs for the healthcare system. Through real-time tissue analysis, LUMA Vision is poised to transform how cardiac treatments are performed, ultimately benefiting both patients and healthcare providers.
Schülke & Mayr
Acquisition in 2020
Schülke & Mayr GmbH, founded in 1889 and headquartered in Norderstedt, Germany, specializes in developing and manufacturing a wide range of hygiene and infection prevention products. The company's offerings include disinfectants, antiseptics, preservatives, biocides, medical skin care products, and active ingredients for deodorants and system cleaners. Schülke & Mayr provides tailored hygiene management solutions to combat hospital-acquired infections and supplies professional hygiene products for medical practices, outpatient surgery departments, and day clinics. Additionally, the company addresses industrial hygiene needs across various sectors, including food processing and the production of sterile medicinal products, along with offering preservatives for cosmetics and household products. Its global presence includes subsidiaries in several countries, enabling it to serve diverse industries such as healthcare, dental, food, pharmaceuticals, cosmetics, and metalworking. The company operates as a subsidiary of L'Air Liquide S.A.
Galderma
Acquisition in 2019
Galderma is a global dermatology-focused company established in 1981, originally as a joint venture between Nestle and L'Oreal. It became a standalone entity in 2019 and is dedicated to providing innovative medical solutions for various dermatological conditions throughout the lifespan of individuals. With a workforce of approximately 6,600 employees and a presence in 80 countries, Galderma offers a diverse product portfolio that addresses issues such as acne, rosacea, psoriasis, and skin cancer. Key brands include Epiduo, Oracea, Differin, and Restylane, among others. The company emphasizes a science-based approach across multiple dermatology categories, including therapeutic solutions, dermatological skincare, and injectable aesthetics.
Pharvaris
Series B in 2019
Pharvaris is a clinical-stage biopharmaceutical company dedicated to the discovery and development of oral therapies for rare diseases, specifically targeting hereditary angioedema (HAE) and other conditions mediated by bradykinin B2 receptors. The company aims to provide alternatives to injectable treatments through its novel small molecules. Pharvaris' lead drug candidate, PHA121, is a potent oral bradykinin B2 receptor antagonist currently undergoing Phase 1 clinical trials. The company's expertise stems from its co-founders, who include key figures involved in the development of icatibant, a well-established treatment for HAE. Pharvaris is committed to addressing significant unmet medical needs in the field of bradykinin-mediated diseases.
Nkarta Therapeutics
Series B in 2019
Nkarta Therapeutics is a biopharmaceutical company focused on developing engineered natural killer (NK) cell therapies for treating various cancers and autoimmune diseases. Unlike T-cell therapies, NK cells have an inherent ability to recognize and destroy abnormal cells without genetic alteration, offering promise for diverse tumor types with potentially better tolerated side effects. Nkarta's approach involves leveraging its NK expansion platform technology alongside proprietary cell engineering techniques to generate a substantial supply of enhanced NK cells that can persistently target and eliminate cancer cells.
Ellab is a manufacturer specializing in thermal validation and monitoring products, providing solutions that measure, record, and validate critical parameters in thermal processing. The company offers a diverse range of high-precision and modular systems, including wireless data loggers and thermocouple-based instruments, designed to support various applications such as sterilization, freeze-drying, environmental chambers, heat tunnels, and pasteurization. With a global presence, Ellab sells its products in over 65 countries, focusing on reducing the time-to-market and minimizing the risk of product loss for its clients.
AM Pharma
Series F in 2019
AM Pharma B.V. is a biopharmaceutical company based in Bunnik, the Netherlands, focused on developing and commercializing novel therapeutics for inflammatory and infectious diseases. Established in 2000, the company specializes in pre-clinical and clinical development using endogenous proteins and peptides derived from the human body. Its key products include alkaline phosphatase, aimed at treating acute kidney injury and ulcerative colitis, and the immune response amplifying peptide hLF1-11, which targets drug-resistant hospital-acquired infections. AM Pharma is committed to providing innovative therapies that enhance patient quality of life by addressing critical medical needs.
DNA Script
Series B in 2019
DNA Script is a pioneering company in the field of DNA synthesis, focused on enhancing life sciences and human health through innovative technology. It has developed the SYNTAX, the world's first benchtop DNA printer, which allows laboratories to produce synthetic oligonucleotides using a novel enzymatic process. This method employs natural enzymes for nucleic acid synthesis, enabling rapid and efficient production of critical genomic experimental precursors. By providing greater control over workflow and accelerating access to results, DNA Script supports researchers in advancing experiments and developing new therapeutics effectively.
Igenomix
Acquisition in 2019
Igenomix is a company that offers genetic testing services specifically designed for reproductive health patients and clinics. It focuses on various aspects of reproductive genetics, providing services such as non-invasive prenatal testing, carrier genetic testing, preimplantation genetic diagnosis, and endometrial receptivity assessment. In addition to these testing services, Igenomix is involved in developing tools and solutions aimed at enhancing reproductive medicine. The company addresses key factors related to infertility, including embryonic viability and endometrial receptivity, thereby supporting couples who are trying to conceive. Through its specialized offerings, Igenomix plays a significant role in the field of reproductive health.
Snipr Biome
Series A in 2019
Snipr Biome ApS is a biotechnology company based in Copenhagen, Denmark, that focuses on developing innovative CRISPR technology for the treatment of microbial diseases. Incorporated in 2017, the company aims to revolutionize healthcare by utilizing a programmable approach to the adaptive immune system, enabling the targeted elimination of hazardous bacteria based on their specific DNA sequences. Snipr Biome's novel medicines are designed to provide health professionals with effective tools for microbiome engineering, allowing for selective targeting and destruction of harmful bacteria in vivo.
WS Audiology
Acquisition in 2019
WS Audiology A/S is a manufacturer and distributor of hearing instruments and audiological solutions, headquartered in Lynge, Denmark. Established in 2019 through a partnership between Sivantos and Widex, the company aims to enhance hearing care for individuals with hearing needs. Its product offerings include a comprehensive range of hearing aids, such as receiver-in-the-ear devices, assistive listening devices, and solutions for single-sided deafness. Additionally, WS Audiology provides accessories like hearing aid batteries, remote controls, and electronic drying stations. The company's diverse product spectrum caters to various price categories, ensuring that those with hearing loss have access to effective solutions for improved hearing and understanding.
Karo Healthcare
Acquisition in 2019
Karo Pharma is a pharmaceutical company. The company develops and markets products for pharmacies and directly to the healthcare sector. The product portfolio includes over-the-counter and prescription pharmaceuticals as well as medical devices.
XyloCor Therapeutics
Series A in 2018
XyloCor Therapeutics, Inc. is a biopharmaceutical company specializing in the development of gene therapies for cardiovascular diseases, particularly advanced coronary artery disease. Founded in 2013 and based in Newtown Square, Pennsylvania, the company focuses on innovative treatments aimed at addressing significant unmet medical needs. Its lead product candidate, XC001, is currently in clinical development for patients suffering from refractory angina, targeting individuals who have exhausted other treatment options. XyloCor's approach centers on stimulating the formation of new coronary blood vessels to enhance blood supply to areas of the heart that are inadequately perfused, thereby improving patient outcomes in those affected by heart failure and ischemic conditions. The company collaborates with Weill Cornell Medical College to advance its gene therapy technologies.
Lumeon Ltd. is a digital health company based in London, United Kingdom, specializing in care pathway management solutions for the healthcare sector. Founded in 2005 and previously known as Qinec Ltd., Lumeon offers a cloud-based platform called Care Pathway Manager, which provides a comprehensive, real-time view of the patient journey from referral to outcome. The platform enables healthcare providers to unify clinical and administrative workflows, automate tasks, and deliver measurable care, addressing the underlying systems that drive healthcare transformation. Lumeon's clientele includes some of Europe's leading healthcare providers, such as BUPA and Nuffield Health, reflecting its position as a key player in the market. The company employs over 90 professionals dedicated to enhancing patient care through effective management and analysis of healthcare pathways.
Endotronix
Series D in 2018
Endotronix Inc. is a medical technology company based in Lisle, Illinois, founded in 2007. It specializes in the development of advanced hemodynamic monitoring solutions aimed at improving the management of heart failure. The company’s flagship product is a miniaturized, wireless implantable pressure sensor that is designed to be used during interventional cardiovascular procedures. This sensor interfaces with an external measurement device and is part of a broader platform that includes a cloud-based disease management system. Through its innovative technology, Endotronix enables healthcare professionals to detect worsening heart failure earlier, facilitating proactive patient management and enhancing clinical outcomes. The company's approach connects patients, clinicians, and reimbursement teams, providing a comprehensive solution for outpatient hemodynamic management.
HyTest
Venture Round in 2018
HyTest Ltd. is a manufacturer of monoclonal antibodies and antigens specifically for the diagnostic industry, founded in 1994 and headquartered in Turku, Finland. The company specializes in developing innovative solutions for assay development and research applications, providing a range of products and services that include antibodies, antigens, and various biomarkers. HyTest's offerings are utilized across multiple clinical areas, such as cardiac markers, infectious diseases, metabolic syndrome, and veterinary diagnostics. By focusing on research and development, HyTest enables its clients to deliver accurate testing solutions in the in vitro diagnostic sector.
Artios Pharma
Series B in 2018
Artios Pharma Limited is a biotechnology company based in Cambridge, United Kingdom, that specializes in developing innovative cancer treatments targeting DNA damage response (DDR) pathways. Founded in 2016, the company is dedicated to creating first-in-class therapies that selectively kill cancer cells by exploiting their reliance on DDR mechanisms. Artios’ product pipeline includes a range of promising candidates, such as a therapy that targets DNA polymerase theta, a protein involved in DNA repair processes, and another program focusing on a novel DDR target. The company collaborates with prominent research organizations, including Cancer Research Technology, to enhance its development efforts and leverage expertise in DNA repair. Artios is led by a skilled team with extensive experience in drug discovery, positioning it to advance its next-generation DDR programs and contribute significantly to the field of cancer treatment.
Biovian
Debt Financing in 2018
Biovian is a specialized contract manufacturing organization focusing on the biopharmaceutical sector, providing comprehensive services from early development to the production of finished vials. Established in 2003, the company operates out of a 2700 m² facility that is both EMA certified and FDA inspected for cGMP production, ensuring compliance for investigational and commercial products. Biovian caters primarily to small and medium-sized biotechnology firms, offering expertise in biopharmaceutical process development, GMP manufacturing, and quality assurance. The company's capabilities enable clients to effectively develop innovative gene therapies and biopharmaceuticals, supporting the advancement of healthcare solutions.
Merus B.V. is a clinical-stage biomedical company focused on the discovery and development of innovative antibody-based biopharmaceuticals. The company specializes in bispecific antibody therapeutics, utilizing its proprietary Oligoclonics technology to produce a unique class of human antibodies. This technology enables the generation of a mixture of therapeutic antibodies targeting a common antigen from a single cell clone. Merus is also advancing its full-length human multispecific antibody therapeutics, known as Biclonics. The company has a diverse pipeline of product candidates, including MCLA-128, MCLA-117, and MCLA-158, among others, all designed to address various challenges in immuno-oncology.
Simplify Medical
Series B in 2018
Simplify Medical, Inc. is a medical device company specializing in the design, development, manufacturing, and marketing of cervical and lumbar artificial discs intended for spinal use. Founded in 2013 and based in Sunnyvale, California, it offers innovative products such as the Simplify Disc, a non-metallic, MRI-compatible artificial cervical disc that preserves motion while allowing for full diagnostic imaging without the need for traditional CT scans. This technology minimizes patient exposure to ionizing radiation and is tailored for skeletally mature patients undergoing reconstruction at one level from C3 to C7 following discectomy procedures. Simplify Medical markets its products through distributors in the United Kingdom, Germany, and other international markets. The company was previously known as Simplify Delaware, Inc. before rebranding in February 2015.
Nouscom is a biotechnology company focused on developing an immunotherapy platform that creates engineered viral vector vaccines for cancer treatment. The company's innovative platform leverages a portfolio of modified viral vectors, specifically designed for the efficient expression of long strings of tumor neoantigens. This approach is complemented by a toolkit that facilitates the induction of robust antitumor T-cell responses, effectively enhancing cancer-specific cellular immunity in patients. Through its research and development efforts, Nouscom aims to improve cancer treatment outcomes by harnessing the body's immune system to target and combat cancer cells.
Simplify Medical
Series B in 2017
Simplify Medical, Inc. is a medical device company specializing in the design, development, manufacturing, and marketing of cervical and lumbar artificial discs intended for spinal use. Founded in 2013 and based in Sunnyvale, California, it offers innovative products such as the Simplify Disc, a non-metallic, MRI-compatible artificial cervical disc that preserves motion while allowing for full diagnostic imaging without the need for traditional CT scans. This technology minimizes patient exposure to ionizing radiation and is tailored for skeletally mature patients undergoing reconstruction at one level from C3 to C7 following discectomy procedures. Simplify Medical markets its products through distributors in the United Kingdom, Germany, and other international markets. The company was previously known as Simplify Delaware, Inc. before rebranding in February 2015.
Luxendo is a company that specializes in the development and manufacture of advanced Single Plane Illumination Microscopes (SPIM), a technology initially developed at the European Molecular Biology Laboratory (EMBL). By utilizing a light-sheet fluorescence microscopy technique, Luxendo's instruments facilitate rapid three-dimensional imaging of living organisms, including spheroids and whole specimens, without the need for sample rotation. This innovative approach allows for gentle handling of delicate samples, such as cell cultures and embryonic specimens, enabling scientists to observe living organisms over extended periods while minimizing photodamage. The company's commitment to revolutionizing bio-imaging positions it as a leader in the field of microscopy, providing researchers with powerful tools for biological exploration.
OxThera AB is a biopharmaceutical company focused on developing innovative therapies for the treatment of primary and secondary hyperoxaluria, a condition that can lead to kidney damage. Founded in 2005 and headquartered in Stockholm, Sweden, with an additional facility in Knoxville, Tennessee, OxThera specializes in products that utilize bacteria and enzymes to manage oxalate levels in the body. Its leading products include Oxabact, an oral formulation of live bacteria designed to enhance the elimination of oxalate produced endogenously, and Oxazyme, a non-systemic oral drug made from recombinant oxalate decarboxylase aimed at treating dietary hyperoxaluria and preventing kidney stones. Oxabact has received Orphan Drug designations in both Europe and the United States, underscoring its potential in addressing unmet medical needs in this therapeutic area. The company holds worldwide patents for its unique compositions and treatment methods targeting hyperoxaluria.
Vivasure Medical
Series C in 2016
Vivasure Medical Limited is a medical device company based in Galway, Ireland, that specializes in the research, development, and manufacture of arterial and venous closure devices utilizing its patented PerQseal technology. The company focuses on creating polymer implants and delivery systems aimed at minimally invasive vessel closures, primarily in cardiology, interventional radiology, and vascular surgery. Its flagship product is an absorbable patch-based large-bore percutaneous closure device, designed to effectively close large arteriotomies resulting from transcatheter procedures, including transcatheter aortic valve replacement and endovascular aneurysm repair. Founded in 2008, Vivasure Medical is committed to advancing techniques that enhance patient outcomes in vascular access procedures.
Rotation Medical
Series B in 2016
Rotation Medical Inc. is a medical technology company based in Plymouth, Minnesota, that specializes in the development of a minimally invasive rotator cuff implant system aimed at treating rotator cuff disease. The company's innovative implant system utilizes a collagen scaffold designed to be affixed to the affected rotator cuff tendon, offering a surgical solution for managing and protecting tendon injuries. This system is particularly beneficial for patients with small rotator cuff tears and provides additional protection for those with larger tears. Founded in 2009, Rotation Medical was originally known as Denali Medical Inc. before rebranding in March 2010. As of December 2017, the company operates as a subsidiary of Smith & Nephew plc.
Press Ganey Associates
Acquisition in 2016
Press Ganey partners with over 10,000 healthcare organizations globally to enhance the quality of care and improve patient experiences. The company provides a range of solutions, including patient-experience measurement, performance analytics, and strategic advisory services, aimed at reducing patient and caregiver suffering while ensuring safety and quality in healthcare delivery. By collaborating with a diverse array of clients, including hospitals, medical practices, and home care agencies, Press Ganey helps organizations operate more efficiently, increase market share, and optimize reimbursement. With its reach extending to approximately 50 percent of all U.S. hospitals, the company is dedicated to fostering high-performing healthcare environments across the continuum of care.
Nouscom is a biotechnology company focused on developing an immunotherapy platform that creates engineered viral vector vaccines for cancer treatment. The company's innovative platform leverages a portfolio of modified viral vectors, specifically designed for the efficient expression of long strings of tumor neoantigens. This approach is complemented by a toolkit that facilitates the induction of robust antitumor T-cell responses, effectively enhancing cancer-specific cellular immunity in patients. Through its research and development efforts, Nouscom aims to improve cancer treatment outcomes by harnessing the body's immune system to target and combat cancer cells.
Onward is a medical technology company focused on developing therapies aimed at enabling functional recovery for individuals with spinal cord injuries. The company is creating an Implantable Neuro-stimulation System (INS) that features real-time motion feedback and utilizes training tools for rehabilitation. Onward has developed two platforms for neurostimulation: ARCIM, an implantable system, and ARCEX, a non-invasive transcutaneous system. To establish its customer base, Onward has targeted the United States and four European markets, namely Germany, France, the United Kingdom, and the Netherlands.
ViCentra B.V., based in Utrecht, the Netherlands, specializes in the development of medical devices, particularly for diabetes management. The company focuses on creating user-friendly and aesthetically pleasing products that aim to enhance the overall experience for individuals managing their health. ViCentra emphasizes the importance of excellent customer experiences and approaches product design with the belief that simplicity and effectiveness lead to better health outcomes. In addition to its operations in the Netherlands, ViCentra also has a presence in the UK, where it continues to innovate in the field of medical devices through dedicated research and development efforts.
Pharvaris
Series A in 2016
Pharvaris is a clinical-stage biopharmaceutical company dedicated to the discovery and development of oral therapies for rare diseases, specifically targeting hereditary angioedema (HAE) and other conditions mediated by bradykinin B2 receptors. The company aims to provide alternatives to injectable treatments through its novel small molecules. Pharvaris' lead drug candidate, PHA121, is a potent oral bradykinin B2 receptor antagonist currently undergoing Phase 1 clinical trials. The company's expertise stems from its co-founders, who include key figures involved in the development of icatibant, a well-established treatment for HAE. Pharvaris is committed to addressing significant unmet medical needs in the field of bradykinin-mediated diseases.
Lima Corporate
Acquisition in 2015
Lima Corporate is the Italian multinational in orthopaedics and traumatology. Lima Corporate is a maker of orthopedic equipment for doctors and healthcare practitioners. The company provides a variety of orthopedics and traumatology surgical equipment and devices, as well as implantable prostheses for knee, hip, shoulder, and minor joint arthroplasty, allowing clients to receive customised hardware that promotes patient-centered treatment.
Luxendo is a company that specializes in the development and manufacture of advanced Single Plane Illumination Microscopes (SPIM), a technology initially developed at the European Molecular Biology Laboratory (EMBL). By utilizing a light-sheet fluorescence microscopy technique, Luxendo's instruments facilitate rapid three-dimensional imaging of living organisms, including spheroids and whole specimens, without the need for sample rotation. This innovative approach allows for gentle handling of delicate samples, such as cell cultures and embryonic specimens, enabling scientists to observe living organisms over extended periods while minimizing photodamage. The company's commitment to revolutionizing bio-imaging positions it as a leader in the field of microscopy, providing researchers with powerful tools for biological exploration.
Neuravi Limited, established in 2009 and based in Galway, Ireland, specializes in designing and developing medical devices for treating acute ischemic strokes. The company's primary product, the EmboTrap revascularization device, is designed to restore blood flow by removing clots from blocked brain arteries. Neuravi operates in multiple European countries and is a subsidiary of DePuy Ireland Unlimited Company.
Merus B.V. is a clinical-stage biomedical company focused on the discovery and development of innovative antibody-based biopharmaceuticals. The company specializes in bispecific antibody therapeutics, utilizing its proprietary Oligoclonics technology to produce a unique class of human antibodies. This technology enables the generation of a mixture of therapeutic antibodies targeting a common antigen from a single cell clone. Merus is also advancing its full-length human multispecific antibody therapeutics, known as Biclonics. The company has a diverse pipeline of product candidates, including MCLA-128, MCLA-117, and MCLA-158, among others, all designed to address various challenges in immuno-oncology.
Ventaleon
Venture Round in 2015
Ventaleon is a biopharmaceutical company focused on developing inhaled treatments for viral infections, with a particular emphasis on severe influenza. Its lead therapy, inhaled LASAG, is a lysin-salt formulation of acetylsalicylic acid, designed for use in inhalable aerosol form. Ventaleon's approach allows for a noninvasive method of treatment, which has shown promising results in clinical trials. A proof-of-concept study indicated that patients receiving inhaled LASAG experienced a more rapid decline in symptoms compared to those receiving standard care. The company is currently preparing to initiate a pivotal clinical trial to further evaluate the efficacy of its lead therapy. Founded in 2012 as a spin-off from Activaero, Ventaleon leverages expertise in aerosol inhalation therapies to advance its innovative treatment solutions.
Affimed NV is a clinical-stage biopharmaceutical company focused on developing innovative cancer immunotherapies. With nearly two decades of expertise in innate immunity, Affimed seeks to leverage the innate immune system to enhance cancer treatment outcomes. The company specializes in discovering and advancing targeted therapies through its unique approach of using innate cell engagers, which aim to address the limitations of existing immuno-oncology therapies. In addition to its core research and development efforts, Affimed also generates revenue by providing research and development services to third parties, utilizing both its own and externally licensed intellectual property.
Rotation Medical
Series B in 2014
Rotation Medical Inc. is a medical technology company based in Plymouth, Minnesota, that specializes in the development of a minimally invasive rotator cuff implant system aimed at treating rotator cuff disease. The company's innovative implant system utilizes a collagen scaffold designed to be affixed to the affected rotator cuff tendon, offering a surgical solution for managing and protecting tendon injuries. This system is particularly beneficial for patients with small rotator cuff tears and provides additional protection for those with larger tears. Founded in 2009, Rotation Medical was originally known as Denali Medical Inc. before rebranding in March 2010. As of December 2017, the company operates as a subsidiary of Smith & Nephew plc.
Heart Metabolics
Series A in 2014
Heart Metabolics Limited is a pharmaceutical company focused on developing therapies for hypertrophic cardiomyopathy (HCM), a condition where the heart muscle thickens, making it harder for blood to leave the heart and often leading to heart failure or sudden death. With over 100,000 cases in the United States alone, HCM can be particularly severe in young adults and athletes. Current cardiovascular drugs do not help all patients, highlighting a significant medical need. Heart Metabolics is addressing this by developing perhexiline, an approved drug in Australia and New Zealand for angina, as a therapeutic for all types of HCM. The company plans to conduct clinical trials in the U.S. and seek FDA approval for perhexiline as an orphan drug, which it has already designated.
I-MED Radiology Network
Acquisition in 2014
I-MED Network Radiology is Australia's largest private medical imaging network, operating over 200 clinics across major metropolitan areas and significant rural regions. Annually, the network conducts over 4 million patient examinations, supported by a team of approximately 300 specialist radiologists, 50 nuclear physicians, and 3,900 staff members. The clinics provide a comprehensive range of radiology services, including X-ray, CT, MRI, nuclear medicine, ultrasound, cardiac imaging, and interventional procedures, ensuring high standards of diagnostic accuracy for referring medical practitioners and patients. Established in 2000 and expanded through a merger with MIA Group Limited in 2004, I-MED remains privately owned and is recognized as one of the largest providers of medical imaging services globally.
Merus B.V. is a clinical-stage biomedical company focused on the discovery and development of innovative antibody-based biopharmaceuticals. The company specializes in bispecific antibody therapeutics, utilizing its proprietary Oligoclonics technology to produce a unique class of human antibodies. This technology enables the generation of a mixture of therapeutic antibodies targeting a common antigen from a single cell clone. Merus is also advancing its full-length human multispecific antibody therapeutics, known as Biclonics. The company has a diverse pipeline of product candidates, including MCLA-128, MCLA-117, and MCLA-158, among others, all designed to address various challenges in immuno-oncology.
Terveystalo Healthcare
Acquisition in 2013
Terveystalo is a prominent healthcare service provider based in Finland, specializing in a comprehensive range of medical services. The company caters to corporate, private, and public sector clients, offering primary and specialized healthcare, including general practice, specialist medical care, diagnostic services, outpatient surgery, and dental care. Terveystalo's integrated approach encompasses the entire healthcare treatment chain, ensuring a seamless experience for patients. Additionally, the company operates through three reporting segments: Healthcare Services, Portfolio Businesses, and Sweden, with the majority of its revenue stemming from its Healthcare Services segment. Terveystalo is committed to delivering quality healthcare solutions tailored to the needs of diverse customer groups.
Swiss Smile
Private Equity Round in 2013
Swiss Smile is a dental service provider based in Switzerland, established in 2003 by Haleh Bronner and Golnar Signer. The company specializes in a comprehensive range of dental treatments that include prevention, preservation, tooth extraction and replacement, teeth straightening, beautification, medical procedures, and hygiene treatments. In addition to these services, Swiss Smile also conducts dentistry classes in schools, promoting dental health education. With operations in several cities including Zurich, Baden, Bulach, St. Moritz, Suhr, and Winterthur, Swiss Smile aims to deliver high-quality dental care to a diverse clientele across the region.
Affimed NV is a clinical-stage biopharmaceutical company focused on developing innovative cancer immunotherapies. With nearly two decades of expertise in innate immunity, Affimed seeks to leverage the innate immune system to enhance cancer treatment outcomes. The company specializes in discovering and advancing targeted therapies through its unique approach of using innate cell engagers, which aim to address the limitations of existing immuno-oncology therapies. In addition to its core research and development efforts, Affimed also generates revenue by providing research and development services to third parties, utilizing both its own and externally licensed intellectual property.
IlluminOss
Series C in 2012
IlluminOss Medical, Inc., established in 2007 and headquartered in East Providence, Rhode Island, is a medical device company specializing in orthopedic fracture repair. It designs, develops, and markets products based on its proprietary IlluminOss System, which employs a light-curable polymer within an expandable balloon catheter to create patient-specific intramedullary implants for bone stabilization. This minimally invasive technology is particularly suited for treating osteoporotic and compromised bone. The company's products are CE-marked and FDA-cleared for various anatomical sites and are distributed in several European countries.
Celladon
Venture Round in 2012
Celladon Corporation, established in 2000 and headquartered in La Jolla, California, is a biotechnology company focused on developing molecular therapies for treating heart failure. The company's primary product candidate is MYDICAR, an enzyme replacement therapy aimed at addressing the key enzyme deficiency in advanced heart failure. This therapy targets SERCA2a, an enzyme crucial for regulating calcium cycling and contractility in heart muscle cells.
Prosensa
Venture Round in 2012
Prosensa, also known as Ribpharm Inc, is a biotech company specializing in the discovery, development, and commercialization of RNA-based therapeutics. The company is particularly focused on addressing genetic disorders, with an emphasis on neuromuscular conditions, as well as anti-infectives and oncology. Prosensa aims to leverage its strong intellectual property position to capitalize on emerging market opportunities in the healthcare sector. To optimize its operations, the company adopts a focused business model by outsourcing most activities to specialized organizations. Through its innovative approach, Prosensa seeks to bring novel and commercially viable therapeutic products to market.
Pronota NV is a Belgian company focused on developing and commercializing innovative diagnostics aimed at the early detection of life-threatening conditions and addressing unmet medical needs. Established in 2004 and based in Zwijnaarde, the company specializes in non-invasive, validated protein biomarker diagnostics. Its portfolio includes tests for conditions such as heart failure, pre-eclampsia, and sepsis, among others. Pronota is dedicated to enhancing patient care through its proprietary diagnostic solutions. The company benefits from a strong network of investors and key opinion leaders in the medical field, reflecting its commitment to advancing diagnosis and personalized healthcare. Pronota was previously known as Peakadilly NV until its name change in November 2006.
Vivoryon Therapeutics
Venture Round in 2012
Vivoryon Therapeutics AG is a clinical stage biopharmaceutical company based in Halle, Germany, specializing in the research and development of therapeutic products for Alzheimer's disease and cancer. The company's lead candidate, PQ912, is a small molecule QC inhibitor that has completed Phase IIb clinical trials for Alzheimer's disease and is also being explored for cancer treatment. Additionally, Vivoryon is developing PQ1565, a small molecule inhibitor targeting glutaminyl-peptide cyclotransferase-like for cancer therapy, along with a monoclonal antibody aimed at enhancing the clearance of toxic pyroglutamate-Abeta. The company collaborates with various institutions, including the University Medical Center Schleswig-Holstein and Nordic Bioscience, to advance its clinical and research initiatives. Originally founded in 1997 as Probiodrug AG, the company rebranded to Vivoryon Therapeutics AG in June 2019.
Argenx is a global immunology company based in the Netherlands, dedicated to enhancing the lives of individuals affected by severe autoimmune diseases and cancer. The company specializes in antibody engineering technology to develop treatments for rare autoimmune conditions. Its lead product, Vyvgart (efgartigimod), received initial approval in the United States in December 2021 for the treatment of generalized myasthenia gravis, followed by subsequent approvals in Europe and Japan in 2022. Through its innovative approaches, Argenx aims to address significant unmet medical needs in the field of immunology.
Mendor is a Finnish company focused on the design, development, and marketing of advanced diabetes management products. It has introduced an innovative all-in-one blood glucose meter and a web-based software application that simplify daily diabetes management. These products are developed in collaboration with users and diabetes experts, ensuring they meet the specific needs of individuals requiring regular blood glucose monitoring. Mendor's patented software systems deliver real-time diabetes care data, enhancing the efficiency and effectiveness of treatment for patients and caregivers alike.
Nexstim
Venture Round in 2011
Nexstim Plc is a medical technology company based in Helsinki, Finland, specializing in non-invasive brain stimulation technologies. Founded in 2000, the company has developed the SmartFocus technology, which utilizes navigated transcranial magnetic stimulation (TMS) with 3D navigation for precise targeting of brain areas. Nexstim's product offerings include the NBT system, designed for treating major depressive disorder and chronic neuropathic pain, and the NBS system, used for pre-surgical mapping of the speech and motor cortices. The NBS systems are primarily sold to universities and teaching hospitals. Nexstim operates in various markets, including Finland, Europe, and North America, with a significant portion of its revenue generated in North America. The company's commitment lies in addressing significant unmet clinical needs and improving the quality of life for patients.
Argenx is a global immunology company based in the Netherlands, dedicated to enhancing the lives of individuals affected by severe autoimmune diseases and cancer. The company specializes in antibody engineering technology to develop treatments for rare autoimmune conditions. Its lead product, Vyvgart (efgartigimod), received initial approval in the United States in December 2021 for the treatment of generalized myasthenia gravis, followed by subsequent approvals in Europe and Japan in 2022. Through its innovative approaches, Argenx aims to address significant unmet medical needs in the field of immunology.