Madryn Asset Management

Venus Concept Inc. is a medical aesthetic technology company based in Toronto, Canada, specializing in the development and commercialization of minimally invasive and non-invasive devices and treatments. Its diverse product portfolio includes platforms such as Venus Versa, a multi-treatment solution for aesthetic procedures; Venus Legacy, designed for complex face and body needs; and Venus Viva, a customizable skin resurfacing device. The company also offers solutions for hair restoration, including NeoGraft and ARTAS robotic systems, which facilitate follicle harvesting and implantation. Other products address skin tightening, fat reduction, and vaginal health restoration. Venus Concept is recognized for its innovative approach and commitment to enhancing patient experiences within the medical aesthetics sector, generating a significant portion of its revenue from the United States.

Venus Concept Inc. is a medical aesthetic technology company based in Toronto, Canada, specializing in the development and commercialization of minimally invasive and non-invasive devices and treatments. Its diverse product portfolio includes platforms such as Venus Versa, a multi-treatment solution for aesthetic procedures; Venus Legacy, designed for complex face and body needs; and Venus Viva, a customizable skin resurfacing device. The company also offers solutions for hair restoration, including NeoGraft and ARTAS robotic systems, which facilitate follicle harvesting and implantation. Other products address skin tightening, fat reduction, and vaginal health restoration. Venus Concept is recognized for its innovative approach and commitment to enhancing patient experiences within the medical aesthetics sector, generating a significant portion of its revenue from the United States.

Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.

Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.

Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.

Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.

Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.

Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.

Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.

Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.

Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.

Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.

Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.

Greenbrook TMS owns and operates healthcare centers providing repetitive transcranial magnetic stimulation therapy (TMS) for the treatment of major depressive disorder (MDD) and other neurological diseases. Local electromagnetic stimulation is given during TMS therapy to certain brain areas known to be directly involved in mood regulation. Spravato is promoted to treat depressive symptoms in adults with MDD who have suicidal thoughts or behaviors as well as adults with treatment-resistant depression. In order to give patients a thorough treatment experience, Greenbrook handles insurance coverage and handles logistics while keeping the clients informed and involved in the procedure.

Calibrate is a digital health company focused on improving metabolic health to achieve sustainable weight loss. Founded in 2020 and based in New York, Calibrate offers a virtual weight management program that integrates FDA-approved metabolic medications with personalized coaching and a comprehensive curriculum designed by experts in obesity and nutrition. The platform emphasizes behavior change and provides one-on-one virtual sessions with healthcare professionals, aiming to foster lasting habits for its users. Calibrate's approach combines telemedicine with a value-based pricing model, ensuring effective obesity treatment outcomes while facilitating the necessary physiological changes for improved health.

Monteris Medical, Inc. is a medical device company that specializes in developing and marketing technologies for minimally invasive neurosurgery, particularly focused on the treatment of brain lesions. The company's flagship product, the NeuroBlate System, is a laser thermotherapy system designed for the volumetric ablation of pathological brain lesions, including both primary and metastatic tumors. This system utilizes magnetic resonance imaging (MRI) guidance and applies focused laser energy to effectively target and ablate tumors while minimizing damage to surrounding healthy tissue. Monteris Medical also offers various stereotactic anchoring devices for precise image-guided trajectory alignment, as well as stabilization systems for MRI-based procedures that require head fixation. Founded in 1999 and headquartered in Plymouth, Minnesota, the company serves neurosurgeons across the United States through a dedicated sales force. Monteris Medical was previously known as AutoLITT until rebranding in 2003.

Willow Inc., established in 2014 and headquartered in Mountain View, California, specializes in the manufacture of wearable breast pumps for women. The company offers a range of products including milk bags, accessories such as flanges and tubes, and replacement parts. Willow's flagship product is an in-bra wearable breast pump designed to provide mothers with mobility and hands-free convenience during breastfeeding. The company also provides pumping bras, cases, and other breastfeeding essentials.

Alto Pharmacy is a leading digital pharmacy established in 2015, focused on transforming the pharmacy industry through innovative technology and expert pharmacist care. The company aims to enhance the medication experience by providing a more convenient and affordable service, leveraging a mobile app and web portal for medication management and scheduled delivery. Alto has fulfilled over three million prescriptions and has expanded its services to twelve markets, emphasizing the critical role of pharmacists in the healthcare journey. With a strong commitment to customer satisfaction, Alto boasts an industry-leading Net Promoter Score, reflecting its dedication to improving healthcare services for patients.

Bigfoot Biomedical, Inc. is a medical device company focused on transforming diabetes care for individuals with Type 1 Diabetes. Established in 2014 and based in Milpitas, California, the company specializes in developing an integrated diabetes management system that features cloud connectivity and human-centered automation. This system optimizes insulin dosing and delivery through a combination of automated infusion pumps and connected insulin pen options. Bigfoot Biomedical's innovative approach employs machine learning and user-friendly technologies to alleviate the cognitive, emotional, and financial burdens associated with insulin-requiring diabetes. By offering a comprehensive digital drug delivery platform through a unique monthly subscription service model, the company aims to enhance the quality of life for patients managing their diabetes.

Dialyze Direct is a healthcare company that specializes in providing staff-assisted home hemodialysis services for elderly patients suffering from End Stage Renal Disease. The company focuses on delivering customized and coordinated dialysis care through a team of registered nurses, dieticians, and social workers. By offering these services in a home setting, Dialyze Direct aims to improve patient outcomes while reducing overall healthcare costs. The approach not only alleviates the need for transportation but also helps minimize hospital readmissions, thereby enhancing the quality of life for geriatric patients.

SomaLogic, Inc. is a commercial-stage company based in Boulder, Colorado, specializing in protein biomarker discovery and clinical diagnostics. Founded in 1999, the company has developed advanced technologies such as SOMAmers, slow off-rate modified aptamers that specifically bind to target proteins, and the SOMAscan platform, which facilitates comprehensive protein measurement. This innovative approach allows for the analysis of protein biomarker signatures, significantly enhancing the understanding of health and disease beyond traditional genomic methods. SomaLogic's products are utilized in a variety of applications, including diagnostics for conditions in oncology, neurology, and cardiovascular and metabolic diseases, as well as in drug discovery and development. The company also offers diagnostic tests and protein measurement solutions for life science and biopharma researchers, contributing to advancements in medical science.

Aquestive Therapeutics, Inc. is a specialty pharmaceutical company dedicated to developing and commercializing innovative products that address unmet medical needs both in the United States and internationally. The company's commercial portfolio features several oral soluble film formulations, including Sympazan for Lennox-Gastaut syndrome, Suboxone for opioid dependence, Exservan for Amyotrophic Lateral Sclerosis, and Zuplenz for chemotherapy-induced nausea and vomiting. Its pipeline includes advanced candidates such as Libervant, a buccal film for epileptic seizures, and various sublingual films aimed at treating conditions like anaphylaxis and Parkinson’s disease. Founded in 2004 and headquartered in Warren, New Jersey, Aquestive Therapeutics emphasizes its commitment to addressing critical healthcare challenges, particularly in Central Nervous System disorders, while also collaborating with pharmaceutical partners to enhance its product offerings.

Veran Medical Technologies is a medical device company focused on developing minimally invasive solutions for interventional oncology procedures. Based in St. Louis, Missouri, the company offers a range of products, including the SPiNView thoracic navigation system, which aids physicians in performing biopsies on solitary pulmonary nodules for early lung cancer diagnosis. Other key offerings include the ig4 IR System, a platform that assists in biopsies and ablations for various organs, and the SPiNPerc device for hybrid diagnostic procedures. The company also provides vPad2, a tracking device for instrument positioning during surgery, and the vTrack 2.0 Instruments, which guide physicians to peripheral lung regions. Veran's technology enhances diagnostic accuracy and therapy delivery by integrating various imaging modalities, ultimately aiming to improve patient outcomes through earlier cancer detection and treatment.

SomaLogic, Inc. is a commercial-stage company based in Boulder, Colorado, specializing in protein biomarker discovery and clinical diagnostics. Founded in 1999, the company has developed advanced technologies such as SOMAmers, slow off-rate modified aptamers that specifically bind to target proteins, and the SOMAscan platform, which facilitates comprehensive protein measurement. This innovative approach allows for the analysis of protein biomarker signatures, significantly enhancing the understanding of health and disease beyond traditional genomic methods. SomaLogic's products are utilized in a variety of applications, including diagnostics for conditions in oncology, neurology, and cardiovascular and metabolic diseases, as well as in drug discovery and development. The company also offers diagnostic tests and protein measurement solutions for life science and biopharma researchers, contributing to advancements in medical science.

Establishment Labs S.A. is a medical technology company based in Alajuela, Costa Rica, that specializes in the design, development, manufacturing, and marketing of silicone-filled breast and body shaping implants. The company's flagship product line, Motiva Implants, features a variety of options in surface, shape, size, base, and projection and is sold in over 60 countries. Establishment Labs also offers innovative solutions such as the MotivaImagine application, which aids in surgical planning, and Q Inside Safety Technology, a radio frequency identification transponder that provides surgeons with implant-specific data. Additionally, the company provides Puregraft technology for purified fat reinjection and operates a center for breast augmentation consultations. Its manufacturing facilities comply with FDA and ISO standards, and the company has regulatory offices in the United States and a distribution center in Belgium. Established in 2004, Establishment Labs serves plastic surgeons and patients globally, emphasizing innovation in its product offerings.

BioQ Pharma is a specialty pharmaceutical company focused on developing and commercializing a range of ready-to-use infusible pharmaceuticals designed for post-surgical pain management, anesthesia, and sedation. Its product portfolio includes Ropivacaine for pain relief and Propofol for anesthesia, along with pipeline candidates in antibiotics and oncology. The company utilizes a proprietary unit-dose infusion system that enhances safety and efficiency at the point of care, addressing key issues such as medication errors and sterility. BioQ Pharma partners with several organizations, including Novartis' Sandoz unit and Cipla, to market its products across the U.S., European, and Asian markets. Established in 2003 and headquartered in San Francisco, California, BioQ Pharma also has operations in Gent, Belgium. The company was previously known as BioQuiddity Incorporated until its rebranding in 2015.

BioQ Pharma is a specialty pharmaceutical company focused on developing and commercializing a range of ready-to-use infusible pharmaceuticals designed for post-surgical pain management, anesthesia, and sedation. Its product portfolio includes Ropivacaine for pain relief and Propofol for anesthesia, along with pipeline candidates in antibiotics and oncology. The company utilizes a proprietary unit-dose infusion system that enhances safety and efficiency at the point of care, addressing key issues such as medication errors and sterility. BioQ Pharma partners with several organizations, including Novartis' Sandoz unit and Cipla, to market its products across the U.S., European, and Asian markets. Established in 2003 and headquartered in San Francisco, California, BioQ Pharma also has operations in Gent, Belgium. The company was previously known as BioQuiddity Incorporated until its rebranding in 2015.

Venus Concept Inc. is a medical aesthetic technology company based in Toronto, Canada, specializing in the development and commercialization of minimally invasive and non-invasive devices and treatments. Its diverse product portfolio includes platforms such as Venus Versa, a multi-treatment solution for aesthetic procedures; Venus Legacy, designed for complex face and body needs; and Venus Viva, a customizable skin resurfacing device. The company also offers solutions for hair restoration, including NeoGraft and ARTAS robotic systems, which facilitate follicle harvesting and implantation. Other products address skin tightening, fat reduction, and vaginal health restoration. Venus Concept is recognized for its innovative approach and commitment to enhancing patient experiences within the medical aesthetics sector, generating a significant portion of its revenue from the United States.