MassChallenge

Powerhouse, LLC is a Kansas-based company specializing in market research, sports marketing, style guide development, and trademark licensing. It operates from Overland Park, Kansas. Meanwhile, Powerhouse Retail Services, LLC, founded in 1996 and located in Crowley, Texas, offers a comprehensive range of national construction services and facility maintenance. Their services encompass remodels, multi-unit programs, tenant improvements, project management, and a variety of facility maintenance activities, including landscaping, snow removal, and emergency services. The company also provides rollout services such as digital branding and specialty fixtures. Powerhouse Retail Services utilizes advanced technology and project management software to enhance operational efficiency and improve brand presence for its clients. Continuous improvement and sustainable practices are central to their business model, ensuring high-quality service and customer satisfaction.

Founded in 2022 and headquartered in Houston, Texas, Bairitone Health develops innovative solutions for individuals with untreated obstructive sleep apnea. The company's core technology employs remote passive sensing and artificial intelligence to pinpoint structural collapses in the upper airway during sleep, enabling more informed treatment plans.

XN Health is a medical device company founded in 2021 and based in Texas, USA. The company focuses on developing innovative healthcare solutions to assist mechanically ventilated patients in weaning off ventilators more efficiently. Its primary product utilizes phrenic nerve stimulation to induce diaphragm contractions, thereby mitigating the risks of diaphragm dysfunction associated with prolonged mechanical ventilation. By enhancing the weaning process, XN Health aims to improve patient outcomes and facilitate recovery in critical care settings.

InterGen Data develops cloud-based AI software solutions that help financial services firms, healthcare providers, and insurance companies identify and prepare for clients' life events. Its proprietary algorithms analyze data to predict life event occurrences, enabling businesses to address coverage gaps, mitigate risks, and uncover revenue opportunities.

The Whisper Company, founded in 2019 and based in Austin, Texas, specializes in developing products and services aimed at ensuring privacy and secure communication. The company has created an AI-enabled communications platform that prioritizes the confidentiality of interactions between electronic devices. Its flagship application utilizes invisible ink technology, which is biometrically secure, to facilitate private communications. This innovative approach ensures that only the intended sender and receiver can access the transmitted content, thereby providing end-to-end encryption and enhancing the overall security of conversations.

SignTracker, headquartered in Austin, Texas, specializes in creating software and online tools tailored for the sign industry. Their solutions assist sign shops in organizing tasks, calculating price quotations, and tracking project progress. The company's tools are designed to help businesses plan, stay organized, keep teams on track, and provide accurate quotes to customers, ultimately aiding in efficient business management and growth.

Founded in 2018, M Aerospace RTC is an aerospace company based in Austin, Texas. It specializes in large-scale metal 3D printing technology and services, offering a wide range of metal materials and the capacity to produce large pieces.

Intelligent NanoFiber, Inc. is a company that specializes in the design and manufacturing of advanced NanoFiber, an absorbent nano-material with the capability to capture and neutralize toxins and infectious diseases. Founded in 2020 and headquartered in College Station, Texas, the company’s innovative material, composed of polypropylene, offers high absorption characteristics suitable for a variety of applications. These include air filtration, waste management, heat insulation, and environmental restoration efforts such as desert greening. Intelligent NanoFiber serves critical sectors such as public safety and defense, providing solutions that enhance safety and efficiency in addressing environmental and health-related challenges.

Grain4Grain is a San Antonio-based food-tech startup that has developed an innovative process to dry and mill brewers spent grain into low-carb, high-protein flour. This sustainable ingredient is produced affordably by reducing the drying time from six hours to under twenty minutes. Since its launch ten months ago, Grain4Grain has upcycled 120,000 lbs of wet spent grain and launched two consumer products in nearly 200 stores.

Zibrio specializes in advanced balance diagnostics. It leverages NASA technology originally used on astronauts, along with machine learning, to measure subtle changes in balance. Incorporated in 2017, Zibrio aims to empower users to manage their health proactively by providing insights into their balance profiles.

Founded in 2014, Gig Wage is a Dallas-based fintech company specializing in payroll solutions for gig workers and contractors. Its platform enables businesses to efficiently manage contractor payments and compliance while providing transparency to gig workers.

Muxy, Inc. is a company that specializes in designing and developing interactive streaming software tailored for live broadcasters, particularly on the Twitch platform. Founded in 2015 and based in Austin, Texas, Muxy creates a variety of tools aimed at enhancing the streaming experience for both content creators and their audiences. Its offerings include the Muxy Extension Development Kit, which provides a library and backend for creating Twitch extensions, and Muxy Alerts, which generates customizable notifications for followers, donations, subscriptions, and hosts. Additionally, Muxy's platform supports the development of interactive live video applications, enabling real-time audience engagement and analytics, thus facilitating a new revenue stream for streamers.

Founded in 2009 and based in Austin, Texas, Articulate Labs develops wearable medical devices that enhance joint rehabilitation. Their primary product, KneeStim, uses neuromuscular electrical stimulation to strengthen knee muscles during everyday movement, aiding in the treatment of knee osteoarthritis.

Noleus Technologies develops a novel medical device that accelerates patient recovery after abdominal surgery by preventing post-operative ileus and intestinal wall edema. This reduces length of stay for patients, saving time for physicians and costs for hospitals.

Hashing Systems is a technology company based in Dallas, Texas, founded in 2018, that focuses on providing tools and services for the development of decentralized applications (DApps) on the Hedera Hashgraph platform. The company offers a variety of products including Hash.js, which enables secure key interactions; Composer, a tool for interacting with Hedera smart contracts; and a Decentralized Web Console for managing smart contracts and storage. Hashing Systems also provides the Hash Name Service, allowing developers to manage identities, and DailyStamp.io, a social media platform based on Hashgraph. Additionally, MyHBARTokens.com serves as a web wallet for users to transact using HBAR and ERC20 tokens. These offerings collectively aim to simplify DApp development and enhance resource sharing in the decentralized finance sector.

Tellinga (like telling a story) is a Houston, TX-based start-up that creates personalized hand-drawn greeting cards that tell your story through snail mail. Story recipients receive illustrated stories about themselves based on unique preferences. It can be fun, dramatic, thoughtful... anything! Here's how it works: 1. Select your story length (options-one day, one week, two weeks, or one month) 2. Upload a photo and add a description of your desired story (you can reminisce a memory from your past or create a brand new story 3. Our team of talented illustrators and artists will start working on your story 4. A few days later, the designated recipient of the story will start receiving unique hand-drawn greeting card-sized illustrations every other day in their mailbox until the package ends

Sano Chemicals is an early‑stage biotechnology company that develops novel anti‑infectives for clinical and agricultural use. The company focuses on antifungal treatments for human infections such as nail, skin, and systemic diseases, and on bio‑control methods to protect crops from fungal pathogens. Its flagship compound, occidiofungin, was discovered by researchers at Mississippi State University and Texas A&M University and is being advanced for both medical and agricultural applications. In addition to antifungal work, Sano Chemicals explores therapies against antimicrobial‑resistant fungi and bacteria and investigates potential uses in oncology, aiming to improve patient outcomes and support a sustainable food supply.

Founded in Austin, Texas in 2019 by Wangda Li, Arumugam Manthiram, and Evan Erickson, TexPower designs and manufactures lithium-ion battery cells. The company specializes in producing cobalt-free, high-capacity cathode materials for lithium-based batteries, focusing on customized solutions for various end-users such as electric vehicles, drones, and robots.

TeVido BioDevices, Inc. is a biotech start-up based in Austin, Texas, focused on developing innovative tissue-engineered products for reconstructive surgery. Established in 2016, the company utilizes a platform technology that integrates 3D bio-printing with patients' living cells to create custom grafts. These grafts specifically address unmet needs in reconstructive and cosmetic surgery, particularly for individuals who have lost skin color due to scarring or disease. TeVido's approach aims to enhance the quality of life and self-esteem of those affected by disfigurement while also having potential applications in wound healing and broader cosmetic procedures. Through its advanced manufacturing techniques and cellular therapy innovations, TeVido BioDevices is poised to significantly improve surgical outcomes in the field of reconstructive medicine.

HiPR Innovation, established in 2019 and headquartered in Laredo, Texas, specializes in preventing pressure ulcers among wheelchair users. The company offers a unique pressure management system that provides real-time data points to optimize ulcer prevention. Its flagship product is a one-size-fits-all reactive air pressure cushion, equipped with an intrinsic algorithm to eliminate areas of high pressure and improve patient comfort. HiPR Innovation serves patients, caregivers, and healthcare professionals by empowering them with valuable insights for effective pressure ulcer management.

M1NERAL is a mineral intelligence and transaction platform that aggregates data, applies artificial intelligence, and automates transactions for buyers, operators, and sellers in the minerals and royalties sector. The cloud-based platform provides seller data and insights in a single place, offers a spatial search tool to identify opportunities, and enables collaboration among buyers, sellers, service providers, and financial institutions. It aims to shorten transaction cycles by delivering research, filtering, and actionable intelligence to support asset assessment and deal execution, enabling users to research, compare opportunities, and complete transactions more efficiently.

Founded in 2019, Solenic Medical specializes in the development of a non-invasive medical device that uses alternating magnetic fields to eradicate biofilm on metallic implants. Its technology aims to address complications arising from surgeries like knee and hip replacements, as well as trauma-related implants.

Brazen is a platform for empowering and equipping people with periods. Brazen helps women to have a healthy cycle, feeling good about their body, and being brazen about pursuing their dreams. It was founded in 2019 and headquartered in Austin, Texas.

Founded in 2009 and based in Austin, Texas, Articulate Labs develops wearable medical devices that enhance joint rehabilitation. Their primary product, KneeStim, uses neuromuscular electrical stimulation to strengthen knee muscles during everyday movement, aiding in the treatment of knee osteoarthritis.

Brazen is a platform for empowering and equipping people with periods. Brazen helps women to have a healthy cycle, feeling good about their body, and being brazen about pursuing their dreams. It was founded in 2019 and headquartered in Austin, Texas.

InterGen Data develops cloud-based AI software solutions that help financial services firms, healthcare providers, and insurance companies identify and prepare for clients' life events. Its proprietary algorithms analyze data to predict life event occurrences, enabling businesses to address coverage gaps, mitigate risks, and uncover revenue opportunities.

teleCalm specializes in managed phone services for individuals with cognitive challenges like Alzheimer's. It offers features such as call blocking, real-time alerts, and voicemail retrieval to protect users from unwanted calls, reduce isolation, and alleviate caregiver stress.

VenoStent develops bioabsorbable smart polymer wraps for vascular surgeries. Its flagship product, SelfWrap, is a perivascular wrap designed to reduce failures at the vein-artery junction in dialysis patients by promoting outward vein growth and providing custom-fit mechanical support. The company's technology acts as an external stent, reducing surgery time, infection risk, and wound reopening while improving vein usability and durability.

Austin-based Captain Experiences facilitates convenient online booking of guided outdoor sports experiences, initially focused on fishing. Their platform enables users to search for trips by location, group size, target species, price, and more, ensuring a hassle-free connection with Damn Good Guides in the field.

ElecTrip specializes in premium, eco-friendly transportation services across Texas. Utilizing Tesla Model X vehicles driven by experienced professionals, ElecTrip offers clients a comfortable and efficient travel experience with WiFi connectivity for work during journeys. The service reduces overall travel time compared to flying, providing a cost-effective and convenient alternative.

MDM Wound Ventures Inc. is a medical device manufacturing company based in Schertz, Texas, focused on developing innovative products for wound care and surgical applications. The company is known for its EZ Debribe, a sharp debridement instrument designed to provide clinicians with a precise and disposable option for debriding wounds. Founded in 2014, MDM Wound Ventures aims to enhance patient outcomes while reducing costs in the healthcare sector. The company specializes in manufacturing debridement equipment characterized by a uniform cutting plane and cutting flutes, allowing for effective and efficient wound treatment.

SipScene is a social community that allows users to create their own events and sell tickets through a platform. SipScene offers an instant community to have real conversations in an inviting space where everyone is owning the purpose of finding their people. It makes it easy and fun to meet new people with similar interests and make amazing memories. SipScene was founded in 2017 and is headquartered in Austin, Texas.

MicroRio is a biotechnology company founded in 2018 and headquartered in Austin, Texas. The company specializes in producing polyhydroxyalkanoate (PHA) plastics using a bioprocess that converts methane, sourced from natural gas, into biodegradable plastic through the action of bacteria. This innovative approach allows MicroRio to utilize a low-cost raw material that does not compete with food production or arable land, making its PHA products competitively priced compared to conventional plastics. By focusing on sustainable practices and leveraging advanced technology, MicroRio aims to provide environmentally friendly alternatives to traditional plastics while maintaining affordability in the market.

Moolah U, LLC is a company based in Austin, Texas, that specializes in financial education programs for children and teenagers. Founded in 2007, Moolah U offers a variety of engaging learning experiences, including camps, games, and at-home activities, designed to teach young people about money management and personal responsibility. The company has developed a kid-friendly app that encourages smart financial habits by allowing children to prioritize their savings goals according to their individual interests. Through its innovative approach, Moolah U aims to equip the next generation with essential financial literacy skills.

Topl is a blockchain-based technology company that enables organizations to monetize ethical and sustainable practices by recording verified impact on a transparent, auditable ledger. It provides a decentralized protocol and accompanying services designed to build an impact technology economy, allowing enterprises to prove and monetize their positive impact as an asset across industries and borders. The Topl platform offers blockchain infrastructure, a blockchain for impact verification, and hosted tooling that simplifies interaction with the network, including supply chain certification and related services. By combining cross-border projects with verifiable impact data, Topl helps brands unlock value from social and environmental programs while providing a scalable solution for impact monetization.

SurviVR is a Dallas-based company established in 2018 that provides a virtual reality training platform focused on enhancing the decision-making and response capabilities of first responders, particularly in law enforcement. The platform offers immersive and data-driven training experiences designed to improve public safety by enabling officers to engage in thought-provoking and high-pressure simulations. SurviVR's innovative approach aims to enhance the judgment and performance of first responders, ultimately contributing to more effective public safety outcomes.

Topl is a blockchain-based technology company that enables organizations to monetize ethical and sustainable practices by recording verified impact on a transparent, auditable ledger. It provides a decentralized protocol and accompanying services designed to build an impact technology economy, allowing enterprises to prove and monetize their positive impact as an asset across industries and borders. The Topl platform offers blockchain infrastructure, a blockchain for impact verification, and hosted tooling that simplifies interaction with the network, including supply chain certification and related services. By combining cross-border projects with verifiable impact data, Topl helps brands unlock value from social and environmental programs while providing a scalable solution for impact monetization.

GrubTubs Inc. is a company focused on developing animal feed for local family farms by repurposing food waste. Founded in 2016 and headquartered in Austin, Texas, GrubTubs collects leftover food from restaurants and delivers it to local farms, where the food is transformed into chicken feed. Additionally, the company cultivates insects that serve as a nutritious food source for chickens, pigs, and fish. By implementing a waste collection system that includes providing restaurants with specialized tubs for food scraps, GrubTubs helps restaurant owners manage and reduce food waste while fostering a connection between urban eateries and rural agriculture.

Sempulse specializes in advanced sensor systems designed for battlefield triage. Their flagship product, FieldVitals, enhances prehospital care by providing real-time patient health data and prioritizing multiple casualty cases. The company is composed of biomedical engineers, hardware specialists, software developers, and former U.S. military officers, with headquarters across Arizona, California, Texas, and Illinois.

Tiny House Coffee Roasters is an Austin-based micro-roastery that focuses on producing specialty coffee, particularly direct-trade Nicaraguan varieties. The company is committed to delivering sustainable and ethical beverages to both individuals and local businesses. It is known for its signature nitro cold brew coffees and teas, crafted in small batches to enhance flavor and quality. By prioritizing affordability, Tiny House Coffee Roasters aims to provide customers with exceptional coffee that they can feel good about consuming.

Founded in 2014, Cloud Dentistry operates a cloud-based platform that enables dental offices to connect with dental staff in real-time. Its digital platform and mobile application facilitate messaging, booking of professionals on demand, hiring services, submission of patient histories and x-rays, and direct communication with specialists.

EllieGrid Inc. is a technology company specializing in medication management solutions. Founded in 2015 and based in Austin, Texas, the company develops a Bluetooth-enabled pill box designed for individuals and families to organize and manage their medications effectively. This innovative product is complemented by a mobile application that allows users to program reminders, receive notifications for medication times, and maintain a comprehensive list of their medications. Additionally, EllieGrid's system collects compliance data, providing caregivers and healthcare professionals with real-time insights to facilitate timely interventions when necessary. The company sells its products online, aiming to enhance medication adherence and improve healthcare outcomes for users.

Atlas Sensor Technologies is focused on developing innovative sensors aimed at enhancing the efficiency of water softeners and other water treatment systems. The company is working on a patent-pending hardness sensor that addresses critical environmental concerns by significantly reducing the amount of salt discharged into municipal sewer systems and minimizing water waste. This technology, developed at The University of Texas at El Paso, will be transformed into a market-ready product for established water softener manufacturers. By providing solutions that enable consumers to utilize soft water effectively, Atlas Sensor Technologies aims to promote reduced detergent usage in both household and industrial contexts. The company also has plans to explore additional applications for its sensor technology, indicating a commitment to expanding its impact in the water treatment sector.

FunnelAI is a B2B SaaS company founded in 2017 and headquartered in San Antonio, Texas. It specializes in developing artificial intelligence-powered solutions for social selling, enabling businesses to connect with prospective customers in real-time. By analyzing social data from various platforms such as social media, forums, and open Q&A sites, FunnelAI identifies individuals expressing intent to purchase specific products or services. This approach allows the company to deliver clean and qualified leads, providing insights into individual purchase patterns and facilitating real-time interactions between businesses and potential customers. FunnelAI's platform, which utilizes advanced statistical modeling and natural language processing, is designed to be more efficient and targeted compared to traditional advertising methods, ultimately driving higher conversion rates for its clients.

BlockMedx, LLC, founded in 2017 and based in Austin, Texas, specializes in developing a secure, HIPAA-compliant e-prescribing and analytics ecosystem. This innovative platform utilizes the Ethereum blockchain to facilitate the transmission of DEA-controlled drug prescriptions, including opioid pain relievers, directly from physicians to pharmacies. By ensuring a secure and reliable method of communication, BlockMedx aims to mitigate the risks associated with prescription forgeries, duplicates, and over-prescribing. Additionally, the company incorporates predictive analytics to assess patient risk behaviors and promote healthy practices through an internal token economy, contributing to efforts to address the prescription opioid crisis.

Yotta Energy Inc., founded in 2016 and based in Austin, Texas, specializes in the manufacture of innovative solar storage solutions. The company's flagship product, SolarLEAF, is a modular energy storage device that integrates with photovoltaic panels, designed to lower costs and enhance the resiliency of energy storage systems. By significantly reducing the soft costs associated with the design, installation, and maintenance of energy storage, SolarLEAF provides a more efficient alternative to traditional centralized systems. Additionally, Yotta Energy offers SolarPLEXUS, a gateway that optimizes the operation of SolarLEAF units and facilitates connectivity within the system. Their software platform further aggregates energy data to support utilities in managing grid operations and enables system owners to effectively manage their power and reduce expenses.

Resthetics, founded in 2015 and based in Austin, Texas, specializes in anesthetic recycling services aimed at converting waste anesthetic gas into a renewable resource. The company utilizes a unique porous crystalline organic framework, developed from interdisciplinary research at the University of Houston, which exhibits a high affinity for fluorinated anesthetics and enables the efficient desorption of captured molecules. By recapturing these anesthetics, Resthetics allows manufacturers to acquire them at a lower cost compared to producing new materials. This innovative approach not only helps reduce hydrofluorocarbon emissions from hospitals but also taps into a significant market opportunity. The company has garnered recognition in prominent scientific publications and has secured multiple grants, reflecting its commitment to advancing sustainable practices in the healthcare sector. Additionally, Resthetics holds an exclusive licensing agreement with the University of Houston for its proprietary technology.

SkillsEngine, based in Austin, Texas, provides AI-powered data services and APIs that convert unstructured text into structured occupational metadata. As part of the Center for Employability Outcomes at Texas State Technical College, it translates job descriptions and resumes into skills data to support AI-driven insights for candidate screening, skills matching, reporting, and hiring workflow improvements. The solution integrates with existing software to validate skill requirements for students and streamline recruitment processes.

Black Fret is a community of music fans dedicated to good music, good times and the sustainable success of Austin’s local musicians.

Big Wheelbarrow, Inc. is a company based in Austin, Texas, that specializes in developing an online supply-management platform aimed at connecting wholesale food buyers with local farmers. Founded in 2016, the company streamlines the process of sourcing local products by automating transactional communications between buyers and suppliers. Its technology empowers grocery chains and food service businesses to efficiently manage local food supply chains, allowing them to offer products from small independent growers without incurring additional overhead costs. By providing real-time data for sourcing and marketing, Big Wheelbarrow enables its customers to enhance their operational efficiency, improve profit margins, and effectively capture market share.

The Tiny Heights, LLC is a Houston-based company founded in 2017 that focuses on developing a community of tiny homes, each under 1,000 square feet, to facilitate the transition to home ownership. By providing affordable housing options, The Tiny Heights aims to lower the barriers to entry for potential homeowners. The company offers a platform that allows users to explore various real estate properties through immersive three-dimensional videos, showcasing amenities such as fitness centers, community gardens, walking trails, social areas, and business centers. This innovative approach not only assists home seekers in finding suitable properties but also promotes a sense of community among residents.

Halo Life Science is a company dedicated to enhancing human health and wellness through innovative nutritional solutions. After three years of research and development, the company has introduced Naturalin™, a patent-pending phytonutrient designed to improve the nutritional value of everyday foods and beverages. This multifunctional bioactive is also available in various nutritional supplement formats, making it suitable for addressing chronic conditions, illnesses, and obesity. Supported by research from the Dell Pediatric Research Institute at The University of Texas at Austin, Naturalin™ has been validated for safety and efficacy. Halo Life Science's mission is to provide safe, effective, and accessible food and nutritional products to consumers, ensuring that enhanced nutrition is available to everyone, everywhere.

Shower Stream designs and manufactures motion-activated shower head adapters that reduce water wastage. Based in Austin, Texas, the company's IoT-enabled products are designed to improve hotel profitability by decreasing utility costs and enhancing guest experience.

PrimeVOX Communications is a telecommunications company focused on enhancing communication for businesses and individuals through advanced Internet-based solutions. Established in 2015 by a group of University of Texas at Dallas students, the company initially operated from modest beginnings but quickly evolved by forming strategic partnerships and acquiring a diverse customer base. PrimeVOX specializes in delivering high-quality unified communications services, including Voice over Internet Protocol (VoIP), cloud PBX systems, eFax platforms, and HD voice services. Additionally, they offer features such as conferencing bridges, virtual receptionists, voicemail to email, and various dialing services, all designed to facilitate seamless connectivity for organizations.

Hyliion specializes in developing innovative solutions for clean, flexible, and affordable electricity production. Headquartered in Austin, Texas, the company focuses on distributed power generators that can operate on various fuel sources to future-proof against changing energy economies. Initially targeting commercial spaces, Hyliion aims to provide practical solutions contributing positively to the environment.

Vital Herd develops sensor-based technology to measure temperature, respiratory rate, heart rate, rumen motility, and behavior of animals. The company was founded in 2012 and headquartered in Austin, Texas.

Citybot Inc. is a mobile application company based in San Diego, California, that enables users, both tourists and locals, to create self-guided tours and itineraries. Founded in 2011, Citybot serves a variety of major cities across the United States, including Austin, Boston, Chicago, Dallas, Houston, Los Angeles, Miami, New York, New Orleans, Philadelphia, Portland, San Diego, San Francisco, Seattle, and Washington. The application is designed to enhance the travel experience by allowing users to explore their chosen destinations at their own pace.

Reach Production Solutions is a company based in Houston, Texas, specializing in advanced compression solutions that enhance the production of oil and gas wells. Founded in 2009, it provides innovative technologies for multiphase wells, offering a swift and effective alternative to traditional artificial lift methods. The company's services encompass the evaluation and simulation of well portfolios, as well as the installation, operation, monitoring, and maintenance of its systems throughout the entire production journey. Reach Production Solutions focuses on delivering sustainable production enhancements while minimizing infrastructure complexity and costs. Its technology features fewer moving parts, resulting in lower noise and vibration levels, alongside improved efficiency in gas compression and recovery.