MassChallenge

Embryoxite is a biotechnology company specializing in non-invasive diagnostic services for pre-implantation embryos in human-assisted reproduction. It operates a platform that combines artificial intelligence, metabolomics, embryo imaging, and clinical data to enhance embryo selection accuracy and improve patient outcomes for fertility clinics and reproductive specialists.

HeroSupport is a medical device manufacturing company founded in 2019 and based in Veyrier, Geneva. The company specializes in creating medical immobilization devices designed to enhance patient comfort during clinical procedures. Its innovative technology transforms imaging and treatment tables into personalized support solutions, specifically catering to the needs of patients undergoing prone breast radiotherapy. This approach allows patients to benefit from tailored support, eliminating the need for them to adjust to the standard table. By improving patient comfort, HeroSupport enables healthcare providers to deliver more effective and cost-efficient cancer treatment.

Xibus Systems, Inc. is a company based in Somerville, Massachusetts, that specializes in developing and marketing advanced microbiological analytics and testing tools. These tools are designed to test consumable solutions for pathogens, allergens, and spoilage organisms. The company's innovative platform combines materials science, biotechnology, and optical technology to facilitate quantitative and array-based testing. This approach allows for high throughput and cost-effective solutions with rapid results, making it particularly beneficial for food safety and quality assurance. Xibus Systems aims to create a range of products, including low-cost hardware and consumables, that cater to the growing demand for effective microbiological testing in various industries.

Walkky develops a digital healthcare platform that uses artificial intelligence to analyze electrocardiogram data and build personalized patient profiles. The system detects, predicts, and alerts clinicians to significant cardiac events and abnormal or declining heart function, enabling faster proactive cardiovascular diagnostics.

Curespec is a medical device company developing the Nephrospec, a non-invasive device designed to treat chronic kidney disease and hypertension. By preserving kidney function and delaying the need for dialysis, the technology supports clinicians in managing renal and hypertensive conditions and aims to reduce patient suffering.

DocNexus is transforming the healthcare landscape by utilizing AI-powered knowledge graphs to enhance medical affairs organizations. The company has developed a platform that enables rapid access to insights from millions of scientific publications, clinical trials, and news, significantly reducing the time required to gather critical information. Its offerings include a comprehensive database for key opinion leader (KOL) searches, advanced publication searches to support effective scientific exchanges, and news aggregation to keep clients informed about KOLs' digital media presence. Through these capabilities, DocNexus facilitates seamless connections within the healthcare ecosystem, empowering clients to advance their medical affairs strategies effectively.

HME Square is a healthcare technology company specializing in the development of innovative medical diagnostics and devices. Their primary product is a non-invasive glucose monitoring system, which combines photoacoustics, MEMS device technology, and deep learning algorithms to provide accurate and continuous blood glucose measurement without the need for blood sampling or needles. This technology aims to prevent chronic diseases by enabling users to monitor their sugar levels conveniently and effectively, promoting healthier lifestyles.

Walk With Path specializes in developing wearable products that enhance mobility and provide therapeutic benefits for patients. The company's primary offering is a smart insole equipped with biofeedback and sensors, specifically designed to assist individuals with diabetes in improving balance and preventing foot ulcers. One of their key innovations, the Path Finder, is a medical device aimed at helping individuals with Parkinson's disease manage 'freezing of gait,' a condition where patients feel momentarily stuck. This product has shown efficacy through published evidence in Neurology. Walk With Path also offers data insights and analytics for both end users and healthcare professionals, making their products applicable for daily use and gait analysis in clinical and non-clinical settings.

PlusVitech specializes in developing safe and effective therapeutic treatments for cancer patients. Its innovative approach focuses on non-invasive genetic cancer detection using small molecule and monoclonal antibody therapies, aiming to enable early diagnosis and treatment.

Aevice Health specializes in non-invasive wearable technology designed for real-time monitoring of respiratory health. Their devices facilitate early detection of cardiopulmonary issues by recording relevant historical data regarding symptoms and medication intake, allowing clinicians to track patient responses to treatment effectively even when patients are at home. This approach enhances patient care by delivering critical insights remotely.

electronRx specializes in digital medicine solutions for chronic disease management. They develop personalized healthcare platforms that monitor cardiovascular health remotely, enabling patients to self-manage their conditions with clinical oversight.

Ember Sleep is a healthcare technology company specializing in the development of innovative, non-invasive medical devices for treating sleep apnea. Their platform aims to enhance sleep quality by offering comfortable and effective alternatives to traditional treatments, thereby improving overall patient wellbeing and healthcare outcomes.

Innsightful develops wearable devices that monitor and detect anxiety and stress symptoms using AI and machine learning. Their solution integrates biometrics for early detection and provides access to therapists for personalized recommendations, empowering users to understand and manage their mental health.

Drizzle Health develops affordable, high-performance diagnostics for tuberculosis and other bacterial infections. Their innovative tools enable real-time detection of bacteria in various environments, improving testing accuracy, reducing healthcare costs, and ensuring food and water safety.

Founded in 2022 and headquartered in Houston, Texas, Bairitone Health develops innovative solutions for individuals with untreated obstructive sleep apnea. The company's core technology employs remote passive sensing and artificial intelligence to pinpoint structural collapses in the upper airway during sleep, enabling more informed treatment plans.

IC Innovations develops disruptive technology for respiration measurement and analysis. We are focused on lowering the barriers to access to advanced respiratory assessment, in fields such as sports and healthcare.

Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.

Malama Health improves pregnancy-related outcomes by providing software that enhances the care offered by OB/GYNs. Its platform offers a glucose tracker, identifies food triggers, provides one-on-one coaching, and delivers actionable insights to optimize maternal health.

Corveus Medical is a medical device company focused on innovative solutions for preventing heart failure. The company is developing a neuromodulation device designed to perform nerve ablation through a catheter-based approach. This minimally invasive technology aims to effectively target and access specific tissues, offering a novel treatment option for heart failure. By addressing both the clinical and economic challenges associated with this condition, Corveus Medical seeks to improve patient outcomes and enhance the overall management of heart failure.

Flagler Health is a developer of clinical decision support software aimed at enhancing healthcare delivery. The company's platform leverages patient data and clinical guidelines to assist physicians in identifying beneficial treatment strategies that may have been overlooked. By integrating artificial intelligence technologies, Flagler Health transforms clinics into more efficient health systems, enabling healthcare providers to offer comprehensive care and improve patient outcomes. Its focus on data-driven insights positions Flagler Health as a valuable partner in the healthcare sector, facilitating informed decision-making for clinicians.

DoubleLock Healthcare specializes in developing innovative medical devices aimed at reducing healthcare-associated infections. Their primary product is a novel intravenous (IV) port and syringe system designed to enhance sterility and safety. This system, which does not require alcohol swabs or caps, is engineered to decrease drug leakage, toxic vapors, and medication errors, thereby improving patient safety and lowering healthcare costs.

ZiO Health is a biotechnology company focused on enhancing patient outcomes through its innovative pocket-sized laboratory testing technology. The company has developed proprietary biosensor devices that utilize machine learning algorithms to provide real-time results tailored to individual patient profiles. These multi-functional electronic devices are designed for measuring, testing, and detecting the molecular composition of various chemical and biological substances, enabling users to assess the presence, absence, or quantity of specific target molecules. By delivering quality home diagnostics and personalized testing solutions, ZiO Health aims to empower individuals to optimize their health and prevent illness.

Benten Technologies is a social impact company dedicated to democratizing healthcare through digital therapeutics. With approximately $9 million in non-dilutive funding, the company is developing a pipeline of innovative healthcare solutions aimed at improving access to medical services. In addition to its focus on healthcare, Benten Technologies offers technology consulting services, including application development, management consulting, quality assurance, and research and development. By leveraging proven system integration methodologies and expertise, the company aims to deliver value-driven business solutions that enhance operational efficiency for various organizations.

Women aged 20-45 cannot get screened for breast cancer because existing solutions are unreliable. However, 81% want to. At The Blue Box, we have built a pain-free, low-cost, sensitive, radiation-free device to detect breast cancer in urine with a sensitivity of 83%. In 2024, we’ll launch into the market, bringing The Blue Box to private gynecology clinics with a Diagnostics-as-a-Service subscription model, and a pay-per-test revenue stream that we’ll share with doctors.

Birth By Us empowers mothers and birth attendants to customize their own birthing experience while providing caregivers with the insights and data needed to best assist their birth.

Narval is a biotechnology company specializing in the development of synthetic antibody mimetic proteins (AMPs). These AMPs are significantly smaller than conventional antibodies, yet retain their biological functionality. They offer several advantages, including the ability to penetrate tissue barriers, generate limited immune reactions, target small and hard-to-reach antigens, and withstand heat. This technology enables Narval to create novel first-in-class immunotherapeutics for diseases previously challenging to treat using monoclonal antibodies. Their focus includes respiratory, eye, and autoimmune diseases, with delivery methods such as inhaled antibodies, eye drops, and transdermal patches. Narval leverages machine learning and artificial intelligence to optimize its drug development capabilities.

Auspex Diagnostics is a healthcare technology company that specializes in advanced cancer diagnostics services powered by artificial intelligence. The company's core offering involves analyzing genomic information from patients' tumor samples using proprietary machine learning algorithms. This analysis enables accurate assessment of recurrence risk and drug efficacy, thereby facilitating data-driven decision-making for oncologists and personalized treatment plans for patients.

SafeGuard Surgical is a medical device company focused on improving surgical outcomes and patient safety. It develops innovative, resorbable products designed to enhance colonic anastomotic healing and stability during advanced surgical procedures. These include a resorbable intraluminal stent graft and an extraluminal resorbable graft, along with anvil cap extension arms. By employing these products, SafeGuard aims to reduce surgical complications, lower healthcare costs, and minimize patient recovery time, ultimately preventing mortality and morbidity associated with surgery.

ForesightCares is a technology company specializing in AI-driven healthcare solutions for the elderly. It aims to address the U.S.'s impending healthcare crisis, exacerbated by the growing aging population, often referred to as the "Silver Wave". The company develops AI technology to enhance elder care, focusing on routine motor function assessments. Its innovative system enables early detection and tracking of motor function deficits and fluctuations in older adults with conditions like Parkinson's, mild cognitive impairment, and balance issues. This technology benefits patients, caregivers, and healthcare providers by facilitating better health outcomes and improving quality of life.

Helthy is a technology company that offers a browser extension, integrating with major online grocery retailers, to provide real-time food assessments and personalized recommendations for individuals with diabetes or prediabetes. The platform helps users make healthier choices during online grocery shopping by highlighting suitable alternatives and tracking dietary preferences, thereby supporting better blood sugar level management.

Astron Medtech specializes in developing disposable, minimally invasive surgical devices for tendon repair. Their innovative solutions aim to reduce recovery time by half, from six months to four.

True Concepts Medical Technologies is a medical company headquartered in Centerville, Ohio, founded in 2017. The company is dedicated to enhancing patient outcomes while minimizing financial waste within the healthcare system. It specializes in the development of innovative medical devices aimed at addressing critical areas with high morbidity and mortality, such as accurate sepsis diagnosis and treatment for sudden cardiac arrest. True Concepts' flagship technologies are designed to provide safe, effective, and cost-efficient solutions that reduce errors and ensure consistent clinical delivery. In collaboration with the product design and development team at Pixel and Timber, the company leverages extensive clinical experience to create manufacturable solutions that have the potential to save billions of dollars annually in healthcare costs.

MZP Tech is a medical device company focused on point-of-care coagulation analysis. It develops diagnostic methodologies in hemostasis to support the management of bleeding and thrombotic risk. The company’s coagulation diagnostic device analyzes a small blood sample in minutes using a disposable micro-machined chip and a portable sensing system that measures blood viscosity, enabling early screening for cardiovascular-related diseases and clotting disorders.

Oculogenex is a biopharmaceutical company founded in 2020 and based in La Habra, California. It specializes in the development of gene therapies aimed at treating retinal disorders. The company’s innovative approach involves ocular regenerative gene therapy that protects retinal pigment epithelial cells from oxidative stress-induced cell death, a condition linked to macular degeneration. By focusing on these therapies, Oculogenex seeks to enable researchers to enhance the detection and treatment of retinal-related disorders, contributing significantly to advancements in this critical area of medical research.

Welfie is a school health platform that provides health data assessments, insights, and resources focused on physical health issues such as heart health, nutrition, fitness, and diabetes. It aims to support parents, providers, and population health leaders in making better health decisions for children aged K-12.

CardMedic is a healthcare platform designed to enhance communication between healthcare staff and patients, addressing various barriers such as language differences, visual and hearing impairments, cognitive challenges, and literacy issues. The platform features a comprehensive library of digital flashcards that replicate clinical conversations on common healthcare topics. These flashcards are available in multiple formats, including multilingual options, sign language, easy-to-read text, and read-aloud capabilities. By facilitating clearer communication, CardMedic aims to improve the quality of care and reduce health inequalities, ensuring that patients can access essential healthcare information in a way that is understandable to them. The platform is accessible via smartphones, tablets, or desktops, making it a versatile tool for both patients and healthcare providers.

Eupnoos is a health-tech company specializing in digital lung health solutions. It offers smartphone-based, automated lung function testing and data interpretation for various devices and telehealth platforms.

Patientory Inc., established in 2015 and headquartered in Atlanta, Georgia, specializes in developing a personal healthcare solution named Patientory. This platform enables individuals to securely manage their medical records, monitor chronic illnesses, and access relevant health information. Simultaneously, it facilitates healthcare providers' connection with patients for support and care coordination. By empowering users to control their health data and incentivizing healthier lifestyles through personalized rewards, Patientory aims to streamline interactions between healthcare stakeholders and patients while reducing care costs.

CBOH is a digital health platform that decentralizes control of health identity and data. It empowers users to control their digital health identity and share verifiable health statuses with whom they choose. It is on a mission to destigmatize health testing and eliminate the spread of transmissible infections.

Ferrum Health, Inc. is a health technology company based in Santa Clara, California, that specializes in developing an artificial intelligence platform aimed at preventing medical errors and enhancing patient safety. Incorporated in 2017, Ferrum Health's AI-driven platform analyzes patient data across healthcare systems to identify opportunities for closing gaps in care. The platform features a comprehensive patient safety evaluation system, which includes multiple computer vision algorithms that assess radiologic images for commonly missed conditions, such as lung nodules and fractures. Additionally, it employs proprietary natural language processing algorithms to correlate findings with physician notes, effectively flagging potential oversights for hospital quality officers to address. By integrating AI, Ferrum Health strives to improve patient outcomes and support hospital systems in maintaining high standards of care.

Together by Renee is a free app that uses generative AI to streamline and automate health tasks like ordering refills, booking appointments and completing forms in an easy user experience perfect for the 123 million aging Americans managing diabetes, obesity, hypertension, and more. Together measures vital signs like blood pressure via smartphone camera - with no devices or wearables required. Together requires no data entry, typing or integration to legacy systems, using just AI to automate patient-centric care coordination. 67% of Together’s first 15,000 users are over 55 years of age and Together enjoys NetPromoter score of +85.

HealthOpX is a technology company that specializes in software solutions aimed at enhancing the health of at-risk patients through community-based engagement. It serves community organizations, health systems, and payers, enabling them to effectively implement programs and collaborate with government and healthcare entities. The company's predictive analytics platform assesses the risk of patient readmission, emergency room visits, and morbidity, thereby facilitating improved care coordination and medical adherence. By focusing on patient engagement and quality care outcomes, HealthOpX provides healthcare practitioners with tools to deliver convenient and cost-effective benefits to individuals seeking treatment.

Oculogenex is a biopharmaceutical company founded in 2020 and based in La Habra, California. It specializes in the development of gene therapies aimed at treating retinal disorders. The company’s innovative approach involves ocular regenerative gene therapy that protects retinal pigment epithelial cells from oxidative stress-induced cell death, a condition linked to macular degeneration. By focusing on these therapies, Oculogenex seeks to enable researchers to enhance the detection and treatment of retinal-related disorders, contributing significantly to advancements in this critical area of medical research.

CardMedic is a healthcare platform designed to enhance communication between healthcare staff and patients, addressing various barriers such as language differences, visual and hearing impairments, cognitive challenges, and literacy issues. The platform features a comprehensive library of digital flashcards that replicate clinical conversations on common healthcare topics. These flashcards are available in multiple formats, including multilingual options, sign language, easy-to-read text, and read-aloud capabilities. By facilitating clearer communication, CardMedic aims to improve the quality of care and reduce health inequalities, ensuring that patients can access essential healthcare information in a way that is understandable to them. The platform is accessible via smartphones, tablets, or desktops, making it a versatile tool for both patients and healthcare providers.

Flourish Collective is a digital platform designed to support new and expecting families by enhancing access to maternal healthcare and wellness services. It features a marketplace that offers evidence-based products and vetted maternal wellness services, along with a funding mechanism that allows friends and family to contribute towards a positive birth and parenting experience. By providing resources for pregnancy, birth, and postpartum care, Flourish Collective aims to bridge gaps in maternal healthcare, making essential wellness services accessible to all mothers from pregnancy through motherhood.

Ronawk is a biotechnology company specializing in the development of T-Block technology that produces patient-specific biologics for the treatment of various diseases, including cancer, organ injuries, and burns. The company's proprietary method allows for the growth of primary stem cells in a three-dimensional environment, preserving the essential characteristics of these cells outside the human body. This innovative approach enables the rapid expansion of stem cells, facilitating their use in early-stage diagnostics and the repair of damaged tissues. Ronawk's technology not only enhances the efficiency of growing human cells but also supports tissue generation and disease modeling, making significant contributions to the fields of regenerative medicine and reconstructive surgery.

Newton Tech is a company that specializes in mobile physiotherapy technology aimed at aiding stroke patients. Its primary product, Mobi, provides individualized insights and real-time fall detection and prevention to support recovery. Newton Tech’s approach involves recording a patient's walking patterns to build a unique movement signature, which then generates personalized movement insights. This innovative technology is designed to enhance the rehabilitation process and promote healthier outcomes for individuals recovering from strokes.

WestFace Medical is a medical device company focused on enhancing vascular access procedures through its innovative product, SingleStick™. This device employs patented needle tip imaging using optical coherence tomography (OCT) to provide real-time visualization of the needle's trajectory. SingleStick™ consists of a handheld imaging adapter that can be attached to any hollow bore needle, along with an OCT image processor. The adapter introduces an optical fiber into the needle, allowing clinicians to view anatomical markers in real-time as they perform vascular access. This technology aims to redefine the standard of care in medical procedures, ultimately improving clinical outcomes, reducing costs, and increasing patient satisfaction. By facilitating traditional vascular access techniques with advanced imaging capabilities, WestFace Medical addresses significant challenges in pediatric care and beyond.

Arcascope develops a health app that uses algorithms tracking circadian rhythms to provide personalized recommendations, helping users reset their internal clocks for improved sleep and overall wellbeing.

INIA Biosciences is a developer of innovative medical devices that leverage sound wave technology to create non-invasive, home-administered systems for managing chronic inflammatory diseases. The company focuses on a closed-loop monitoring system designed to treat and prevent organ failure by integrating biomarker monitoring with an ultrasound stimulator. This approach aims to reduce inflammation linked to transplant rejection rates and minimize reliance on immunosuppressant drugs. By providing novel diagnostic sensing capabilities, INIA Biosciences enables physicians to better manage chronic diseases and improve patient outcomes.

MoviWear is a company specializing in medical AI and remote monitoring solutions, with a focus on enhancing the safety and health of seniors. Its flagship platform, MoviWearMED, enables real-time health monitoring through proprietary 5G IoT NurtureWatch wearables. This technology allows for continuous tracking of vital signs, including heart rate, temperature, blood pressure, and oxygen levels, as well as fall detection, whether individuals are at home, in retirement communities, or on the move. Designed to respond to the critical need for 24/7 health monitoring outside of hospital settings, MoviWearMED provides instant alerts when there are significant changes in a patient's condition. Since its establishment in 2017, MoviWear has collaborated with various health and telecommunications companies across North America, Europe, and Israel, aiming to prevent health crises and improve quality of life for seniors.

LIALT Laboratorio de Investigación Alternativa develops toxicological evaluations without the use of animals. LIALT replaces the use of animals through the use of three-dimensional tissues in conjunction with internationally recognized protocols that provide more specific information on the mechanisms of toxic action than that obtained in animals, offering a solution to the problem previously exposed.

ModoScript is a developer of innovative digital healthcare solutions focused on enhancing remote treatment monitoring and big data analytics for high-cost specialty pharmaceuticals, particularly Oral Oncolytics. The company aims to improve the efficiency of medication and treatment protocols, ultimately leading to better patient outcomes in managing chronic diseases like cancer. By leveraging a customizable data analytics model, ModoScript provides pharmaceutical companies, health insurance providers, and medical practices with tools to assess treatment progress and support direct-to-patient clinical trials from home. The company collaborates with mail-order specialty pharmacies and in-office medically integrated pharmacies to facilitate remote treatment delivery. ModoScript is dedicated to ensuring that patients receive high-quality care regardless of their race, condition, or socioeconomic status, striving to make their solutions accessible at no cost to patients while reducing overall industry costs.

Nightingale Caring Solutions enhances hospital operations by offering nursing care analytics. It employs machine learning algorithms to analyze relationships between nurses and patient outcomes, optimizing nurse staffing, scheduling, and assignments.

Uniphage is a biotechnology company specializing in the development of safer and more efficient alternatives to traditional pesticides in plant agriculture. It leverages artificial intelligence and bacteriophages (viruses that infect bacteria) to predict and combat specific bacterial infections. The company's primary focus is on citrus greening, a devastating disease costing the U.S. over $2 billion annually. By employing AI algorithms, Uniphage accelerates the discovery of effective and safe bacterial viruses, aiming to reduce the use of harmful fungicides, bactericides, and antibiotics, thereby minimizing risks to human health and the environment.

Through the experience of 15-year skin optics research, we developed optical modules that work in conjunction with sophisicated algorithms to quantify various skin contents such as hemoglobin, bilirubin, skin collagen, skin oxidative stress, blood glucose variation, and etc. In contrast to the market available wearable optical modules that can only measure heart beat rate, our wearable module design provides much more information for personal health monitoring and thus could have multitude application scenarios with great marketing potential.

NurLabs develops label-free and reagent-free diagnostics to detect cancer early when it is most treatable.

Lab SD offers the EYELIKE Platform which increases access to eye health services for marginalized people through appropriate technology and task-shifting. The company provides technologies that help effectively and efficiently operate international health and international development projects to eradicate poverty.

Neurava is a healthcare company focused on improving the lives of epilepsy patients through the development of non-invasive wearable diagnostic devices. These devices monitor critical biological signals associated with epilepsy and the risk of sudden unexpected death in epilepsy (SUDEP), offering a reliable solution for both patients and their caregivers. By providing accurate and timely alerts, especially during nighttime, Neurava's technology empowers caregivers to respond quickly and take preventive actions, thereby enhancing patient safety and peace of mind. The company's commitment to advancing medical device manufacturing and health diagnostics highlights its role in addressing the challenges faced by those with uncontrolled epilepsy.

FormaPath develops automated laboratory tools that streamline tissue biopsy handling and lymph node isolation for cancer diagnostics. Its hands‑free system prepares tissue samples for pathology, while its instrument separates lymph nodes from adipose tissue, improving diagnostic accuracy and efficiency in pathology labs and cancer research centers.

Digital Patient XP is a digital platform that reimagines the cycle of care. It provides real-time feedback on patients’ progress, recollection, engagement, and other determinants.

Gensor develops a virus testing platform based on the gene field-effect transistor technology.

Fora Health helps patients and clinicians track health and take part in shared decision-making. The company's platform links a patient-facing smartphone app with a clinical team web interface, powering remote patient monitoring and shared decision making. Fora Health is scaled to the needs of clinical teams, configuring data collected from validated ePROs and cognitive assessments, to goal tracking, medication adherence, and side effect tracking.

Yengii Biosciences develops the Galet smartphone microscope for detecting infectious illnesses such as malaria, sleeping sickness, and tuberculosis. The Galet platform is intended to do very complicated blood film analysis in a simple, portable point-of-care tool, which is now limited to high-end laboratories. Making such blood film analysis more available would allow for the early diagnosis of the most serious health concerns, such as malaria, and will save lives.

Afya Pamoja provides healthcare managers with actionable data and insights on the quality of service delivery.

Onye is a health technology company focused on building solutions that power and add value to both patients and healthcare providers. The company's product is a mobile-first web-based electronic health record system for healthcare providers to improve their clinical and administrative workflows.

Lambent Data specializes in creating user-friendly software and powerful data analytics to engage families and individuals in managing their health and social determinants of health. The company collaborates with healthcare providers and social service practitioners to improve outcomes and efficiencies. By supporting employers in this process, Lambent Data aims to enhance the well-being of children and adults while reducing healthcare costs.

Diamante is a company based in Verona, Italy, that specializes in the development and manufacturing of diagnostic devices for autoimmune diseases, utilizing innovative nanomaterials. Founded in 2016, the company leverages plants as bioreactors to produce nanoparticles derived from modified plant viruses. This approach allows Diamante to create advanced tools for diagnosing and potentially treating autoimmune conditions, focusing on sustainable and efficient production methods. Through its research and development efforts, Diamante aims to contribute significantly to the field of autoimmune disease therapy.

BestHealth4U specializes in developing advanced adhesive technologies for medical applications. Their innovative solutions aim to prevent skin injuries, enhance healing, and improve overall patient health by transforming how bandages, dressings, and medical devices adhere to the skin.

Paragon Pure is a food ingredient company specializing in developing natural products that cater to modern dietary needs. They focus on areas such as flavor encapsulation and process engineering, leveraging physical chemistry principles and navigating regulatory spaces to create healthier, sustainable structured fats and flavors.

Paragit Solutions specializes in developing innovative systems for remote patient monitoring and data-driven clinical management of movement disorders, particularly Parkinson's disease. Central to their offerings is the Paragit Sleeve, which employs a patented sEMG (electromyography) technology to gather precise data on muscle activation, movement, and grip force during patients' daily activities. Paragit provides two main software suites for data interpretation: the PD Monitor, tailored for caregivers, which visualizes key motor symptoms like rigidity and tremors to enhance treatment optimization and facilitate telemedicine; and the MD Lab, designed for decentralized clinical trials across various movement disorders. MD Lab enables researchers to analyze over 20 metrics related to disease severity, track trends, and compare groups consistently, with a robust API that supports extensive data access for further analysis. Through these technologies, Paragit aims to improve the management and understanding of movement disorders, enhancing patient care and clinical research.

BioEclosion is a biotechnology company specializing in the development of user-friendly, rapid diagnostic tools. Its core technology, Celifast, is a non-invasive method for detecting celiac disease, validated and patented. The company aims to expand this platform to other emerging diseases, using molecular biomarkers for swift identification. BioEclosion's device comprises a single-use cartridge tailored to each application and a portable, battery-operated reader, making it versatile for human and veterinary health, as well as food and environmental safety.

BrightCure Ltd., established in 2019 and based in London, United Kingdom, specializes in developing probiotic-based therapies aimed at treating urinary tract infections (UTIs). The company focuses on addressing recurrent and difficult-to-treat bacterial infections, a significant health issue affecting 50% of women and 12% of men globally. BrightCure's approach involves utilizing the natural microbiome to reduce harmful bacteria and replenish beneficial bacteria in the vaginal flora, thereby boosting the immune system to promote urinary tract health. The company has garnered recognition through various competitions and accelerators, including selection for Indiebio, the world's largest biotech accelerator.

Digi.Bio is a Netherlands-based company specializing in software development for the healthcare sector, focusing on automating liquid handling processes through advanced microfluidic technology. The company offers a lab-on-a-chip and computational platform designed to enhance the efficiency and accuracy of cell therapy development, allowing for rapid analysis of therapeutic outcomes at the single-cell level. By employing artificial intelligence and electrowetting techniques, Digi.Bio's platform enables medical and pharmaceutical laboratories to automate repetitive workflows, significantly reducing material waste and accelerating the bioengineering process. The innovative solutions provided by Digi.Bio aim to streamline multistep liquid handling applications, replacing traditional pipetting methods and facilitating the advancement of life-saving cell therapies.

FermBiotics is a microbiome company focused on enhancing gut health globally through the production of sustainable, fermented plant ingredients. The firm develops a range of plant and seaweed-based products designed to support gut health, including food ingredients, dietary supplements, and medical foods. By combining prebiotics, probiotics, and bioactive compounds, FermBiotics has created a novel category of fermented products that promote a positive gut microbiome. These innovations are aimed at benefiting both humans and animals, allowing families and pet owners to support the gut health of the elderly and their animals effectively.

Criam is a Portuguese biotechnology company based in Braga that develops portable diagnostic technology for blood typing and infectious disease detection. Its stand-alone platform does not require electricity or laboratory infrastructure, enabling rapid testing at the point of care. A single reader can perform multiple tests using cartridges and computer vision algorithms to detect a broad range of diseases, including HIV, with real-time data to support clinical decisions. The system leverages lab-on-a-chip concepts and biomarker detection algorithms to deliver fast, user-friendly, and cost-effective diagnostics in diverse settings, including remote environments and emergency care.

Strados Labs, LLC is a medical technology company based in Philadelphia, Pennsylvania, specializing in respiratory health management through innovative sensor-based solutions. Founded in 2016, the company has developed a wearable device that provides real-time insights into breathing patterns, sounds, and speed. This device is equipped with clinical-grade biosensors and smart software, allowing for continuous monitoring of respiratory conditions such as asthma and chronic obstructive pulmonary disease. By connecting to a mobile application, Strados enables users and healthcare providers to access and analyze respiratory data, facilitating informed health decisions and remote patient monitoring.

Tellus is a technology company that specializes in wireless, non-invasive health monitoring for elderly care facilities. It uses advanced sensor technology to continuously track vital signs and activities, providing real-time insights and alerts to caregivers. This enables better decision-making during emergencies or to prevent issues proactively, enhancing eldercare quality and operational efficiency.

Semantic Health is a Toronto-based healthcare technology company that uses proprietary artificial intelligence to enhance medical coding, auditing, and clinical documentation improvement processes in hospitals.

UpLift Health Inc., based in Atlanta, Georgia, specializes in developing a digital application aimed at treating depression through cognitive behavioral therapy (CBT). Founded in 2018, the company offers a structured program that consists of twelve weekly sessions, each lasting approximately 40 minutes, designed to teach users effective coping skills. The application incorporates chatbot-guided interactions, allowing users to engage with mental exercises and receive feedback. Additionally, it provides daily tools for users to apply learned skills in their everyday lives. Preliminary research indicates that UpLift's program can significantly reduce symptoms of depression, with a reported reduction of 52% in pilot studies. The company is focused on its mission to assist one million individuals in overcoming depression.

Agamon streamlines radiology workflows by automatically extracting data from reports using proprietary deep learning NLP technology. Its platform facilitates follow-up management for programs like lung cancer screenings and incidental findings.

PainPal is a behavioral health platform specifically designed for individuals suffering from chronic pain. The company offers a telebehavioral health solution that delivers personalized, gamified, and on-demand Cognitive Behavioral Therapy for Chronic Pain (CBT-CP). This innovative approach aims to provide effective treatment and counseling that has been shown to reduce pain and improve overall functioning. By focusing on evidence-based methods, PainPal presents a safe and cost-effective alternative to traditional pain management strategies, addressing the significant challenges posed by the chronic pain and opioid crises.

See Yourself Health is a digital health company that leverages immersive technology, data science, and social learning to enhance health and wellness outcomes. Their platform focuses on peer support, online learning, measurement-based care coaching, and chronic disease management within a virtual health metaverse. By employing a constructivist curriculum and peer networks, the company aims to accelerate behavior change and optimize outcomes for individuals with chronic diseases like diabetes.

TREND Community is a healthcare organization focused on enhancing the quality of life for individuals with rare and chronic diseases. The company has developed a networking platform that utilizes advanced analytics to extract valuable insights from patient and caregiver narratives, including stories, journals, discussions, and surveys. By analyzing this real-world data, TREND Community aims to facilitate the creation of health initiatives that evaluate the effectiveness of various therapies and treatments. Additionally, the platform empowers patients to share their experiences and access medical advice, contributing to a collective understanding of their conditions. Through these efforts, TREND Community seeks to educate patients and support the discovery of new medicines and research, ultimately improving the lives of those affected by chronic illnesses.

Zibrio specializes in advanced balance diagnostics. It leverages NASA technology originally used on astronauts, along with machine learning, to measure subtle changes in balance. Incorporated in 2017, Zibrio aims to empower users to manage their health proactively by providing insights into their balance profiles.

Litesprite, Inc. is a Bellevue, Washington-based company that develops mobile games aimed at helping individuals manage chronic health conditions, particularly stress, anxiety, and depression. Its flagship product, Sinasprite, is a video game designed to guide users through prescribed mental health treatments, enabling them to track their progress and engage with coping mechanisms in real time. The platform provides valuable data to clinicians, allowing them to understand the effectiveness of various treatment options for their patients. Litesprite's innovative approach combines proven medical treatments with interactive gaming to enhance patient engagement and facilitate communication between patients and healthcare providers. The company aims to create a suite of games addressing various health conditions, leveraging the emotional engagement of gaming to promote better health outcomes. Since its incorporation in 2013, Litesprite has been recognized for its potential to make a significant impact in healthcare, winning accolades such as the Robert Wood Johnson Foundation's Games to Generate Data Challenge.

Mosaic health data provides medical records of complete data of a patient's health across the continuum of care

Starling Medical is focused on creating a remote patient monitoring platform that facilitates at-home urine diagnostics, aiming to integrate seamlessly into everyday bathroom routines. The company designs healthcare devices that utilize mass spectroscopy-based sensors for continuous monitoring and early detection of health issues through urine analysis. By tracking changes in urine composition over time, Starling Medical's technology enables timely intervention for patients and healthcare providers, potentially preventing complications and reducing the need for hospitalizations. The organization is dedicated to developing predictive technology that enhances early detection of chronic health concerns, ultimately improving patient outcomes.

PREEMIEr Diagnostics is a healthcare company focused on improving the health outcomes of premature infants, specifically in the prevention of retinopathy of prematurity. The company has developed a diagnostic device that accurately measures blood glucose levels in these vulnerable patients. This technology assists healthcare providers in identifying infants who require adjustments to their glucose levels, facilitating early detection of potential health issues. By enhancing the ability of medical professionals to monitor and manage the health of premature infants, PREEMIEr Diagnostics contributes to better clinical outcomes and overall infant care.

Healium is a technology company that develops mental fitness tools and immersive, bio-data-driven experiences to support self-management of anxiety, sleep issues, burnout, and overall well-being. The platform links real-time biometric data from wearables such as heart rate and brain activity via EEG headbands to personalized video or VR assets, producing reactive media escapes controlled by the user’s physiology. By integrating wearable devices and sensors, Healium delivers data-driven content that adapts to the user in real time, aiming to reduce anxiety, improve mood, and build resilience for individuals and organizations. Peer-reviewed studies have reported rapid mood benefits and anxiety reduction in as little as four minutes.

EyeTrac has developed novel face guard technology for contact sports, which can detect concussions accurately on the field in real-time. The incidence of concussions and traumatic brain injury (TBI) has reached epidemic proportions in sports. There is a growing need on the playing field for a head-worn device that can objectively assess head trauma in real-time. This innovative technology is designed to meet the specific needs of athletes participating in contact sports and address limitations of currently available methods of evaluation. It will provide immediate accessibility with diagnostic accuracy for concussions.

Neurosoft Bioelectronics specializes in developing soft, implantable electrodes designed to interface with nervous tissues. Their flagship product, SOFT ECoG, is a subdural electrode used for recording and stimulating the brain's surface, offering improved recordings, reduced current speed, minimized MRI artifacts, enhanced bio-integration, and precise anatomical targeting.

my110 is a London-based company focused on enhancing athletic performance through innovative health solutions. The company develops a tool designed to monitor and understand athletes' body recovery, enabling them to achieve and sustain peak physical performance. In addition to its emphasis on athletic recovery, my110 adopts a proactive approach to healthcare, utilizing decentralized methods to test and track the most acute diseases. Through its technology, my110 aims to empower individuals in managing their health and optimizing their physical capabilities.

Equine Smartbit, LLC is a company based in Saint Louis, Missouri, that specializes in the design and manufacture of innovative health monitoring devices for horses. Founded in 2016, the company has developed the SmartBit, a device equipped with biometric sensors that allows horse owners, trainers, and veterinarians to monitor and analyze the real-time wellness, health, and performance of horses. The SmartBit measures vital signs such as temperature, heart rate, and blood oxygen saturation, providing critical data that helps in assessing a horse's physical condition during training and competition. The device alerts users when a horse's health status may be compromised, thus facilitating timely interventions. In addition to its hardware, Equine Smartbit offers software tools that enhance the analysis of the collected biometric data, supporting informed decision-making in equine care.

Byteflies is a Belgian-American wearable health company dedicated to transforming healthcare through innovative technology. With its headquarters in Antwerp, Belgium, near key life sciences and clinical research centers, and a secondary office in the San Francisco Bay Area, the company is positioned at the intersection of healthcare and digital innovation. Byteflies develops advanced wearable health applications, including a sensor dot that captures biopotential signals, muscle activity, eye movement, and other activity-related data using an integrated inertial measurement unit. This technology empowers pharmaceutical companies, researchers, and tech firms to enhance healthcare delivery and improve patient outcomes. The team comprises experts in medicine, engineering, and data science, all committed to advancing health monitoring and management.

Steradian Technologies is a biotech company focused on developing innovative, noninvasive diagnostic solutions for infectious diseases. The company has created a rapid COVID-19 detection test that delivers results in just 30 seconds by utilizing a unique focal point projection system that emulates human eyesight. This advanced technology employs photonics to identify pathogens in breath samples, bypassing the need for traditional laboratory equipment and lengthy procedures. By offering a portable diagnostic method that achieves high accuracy in detecting bacteria, viruses, and biomarkers, Steradian Technologies aims to transform patient care and enable clinicians to provide quicker, more precise diagnoses.

Decentriq is a confidential data collaboration platform that enables enterprises to analyze sensitive data without sharing it. Its data clean rooms, powered by confidential computing and cryptography, keep data encrypted throughout its lifecycle and inaccessible to other parties or cloud providers. The platform supports collaboration between data scientists and business users, providing flexible analysis workflows and interoperability with existing technologies. By enabling encrypted, permissioned data partnerships across organizational boundaries, Decentriq helps unlock value from data that would otherwise be too sensitive to use. The company serves privacy- and compliance-conscious industries such as media, healthcare, banking, and the public sector.

Hera - Mi is Specialized in digital medical imaging applied to breast cancer.Hera-MI has developed clinical decision support solutions to help improve early-stage breast cancer detection. Our solutions will improve the quality and accuracy of breast cancer diagnosis while decreasing radiologists’ interpretation time. Patients will be treated more quickly, offering them a better chance of remission. Hera-MI has developed Breast-SlimView, a clinical decision support software based on artificial intelligence and image processing for breast cancer diagnosis. Our partner, Fujifilm is selling Breast-SlimView in France and in the Overseas Territories of France (DROM/TOM). Breast-SlimView is also available for sale all over the world.

EarlySight, a Lausanne-based medical device company, develops technology to detect and treat eye diseases at an early stage. Its flagship work includes a fundus camera that images the retina with high detail by combining eye illumination with real time ocular aberration correction. The company also leverages cellular level imaging and transscleral illumination to monitor day to day treatment effects in a non invasive manner, enabling eye specialists to visualize the morphology of retinal cells. Founded in 2016, EarlySight aims to bring its imaging technology to clinics to improve early diagnosis and treatment of ocular conditions.

PROSPERiA is a social impact company spun off from the MIT Media Lab. It aims to enhance early detection and treatment of chronic diseases in emerging markets using Artificial Intelligence-based solutions.