MassChallenge

Xibus Systems, Inc. is a biotechnology company based in Somerville, Massachusetts, specializing in the development of microbiological analytics and testing tools. The company focuses on creating solutions that detect pathogens, allergens, and spoilage organisms in consumable products. By integrating materials science, biotechnology, and optics, Xibus Systems aims to provide quantitative and array-based testing capabilities that are both efficient and cost-effective. Their innovative technology is designed for high throughput and rapid results, while also featuring a roadmap for compact and handheld hardware options. This unique combination of proprietary materials and biological agents positions Xibus Systems to effectively address the growing demands for food safety and quality assurance in the market.

Embryoxite is a biotechnology company specializing in non-invasive diagnostic services for pre-implantation embryos in human-assisted reproduction. It operates a platform that combines artificial intelligence, metabolomics, embryo imaging, and clinical data to enhance embryo selection accuracy, thereby improving patient outcomes in fertility treatments.

MZP Tech is a company focused on point-of-care coagulation analysis, aiming to improve healthcare delivery through innovative diagnostic methodologies. They develop medical devices capable of rapidly analyzing blood samples, utilizing a disposable micro-machined chip and a portable embedded sensing system. This technology allows for the analysis of a single drop of blood within minutes, measuring blood viscosity. By doing so, MZP Tech enables healthcare professionals to conduct early-stage screenings for various conditions, including cardiovascular diseases, blood-clotting disorders, and hyperviscosity-related issues. Their advancements in hemostasis contribute to better management of bleeding and thrombotic risks, enhancing patient care.

DocNexus is transforming the healthcare landscape by leveraging AI-powered knowledge graphs to enhance access to critical information. The company's platform provides a comprehensive database for key opinion leader (KOL) searches, advanced publication searches, and news aggregation, allowing medical affairs organizations to efficiently find evidence and stay updated on KOLs' digital presence. By delivering insights from millions of scientific publications, clinical trials, and news articles in seconds, DocNexus streamlines the process of connecting healthcare professionals across the ecosystem. This innovative approach enables clients to strengthen their medical affairs strategies and improve scientific exchange.

Helthy is a technology company that offers a browser extension, integrating with major online grocery retailers, to provide real-time food assessments and personalized recommendations for individuals with diabetes or prediabetes. The platform helps users make healthier choices during online grocery shopping by highlighting suitable alternatives and tracking dietary preferences, thereby supporting better blood sugar level management.

Drizzle Health develops low-cost, high-performance tuberculosis and other bacterial disease diagnostics.

Malama is a developer of a personalized support platform aimed at improving pregnancy-related health outcomes, particularly for individuals managing diabetes during pregnancy. The platform offers tools for tracking glucose levels and meal intake, helping users identify dietary triggers and trends. Additionally, it provides access to one-on-one coaching, facilitating the optimization of health throughout pregnancy. By delivering actionable insights, Malama empowers patients to enhance their health and well-being during this critical period.

Women aged 20-45 cannot get screened for breast cancer because existing solutions are unreliable. However, 81% want to. At The Blue Box, we have built a pain-free, low-cost, sensitive, radiation-free device to detect breast cancer in urine with a sensitivity of 83%. In 2024, we’ll launch into the market, bringing The Blue Box to private gynecology clinics with a Diagnostics-as-a-Service subscription model, and a pay-per-test revenue stream that we’ll share with doctors.

Walk With Path develops wearable products aimed at improving mobility and health for patients, particularly those affected by diabetes and movement disorders. The company’s flagship offering is a smart insole equipped with biofeedback technology and sensors, designed to enhance balance and prevent complications such as foot ulcers in diabetic patients. Additionally, Walk With Path has introduced Path Finder, a specialized shoe designed for individuals with Parkinson's disease to alleviate the 'freezing of gait' phenomenon, which can leave users feeling immobilized. Path Finder is recognized as a medical device with supporting evidence published in Neurology. The company's products not only provide therapeutic benefits but also offer data insights and analytics for both end users and healthcare professionals, facilitating gait analysis and promoting better mobility in various populations.

Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.

Benten Technologies is a social impact company dedicated to democratizing healthcare. The organization has secured approximately $9 million in non-dilutive funding to develop a pipeline of digital therapeutics aimed at making healthcare services more accessible. In addition to its healthcare initiatives, Benten Technologies also provides technology consulting services, which encompass application development, management consulting, quality assurance, and research and development. By leveraging proven system integration methodologies and expertise, the company enables organizations to deliver effective, value-driven business solutions.

True Concepts Medical Technologies is a medical device company dedicated to reducing financial waste in the healthcare system while enhancing patient outcomes. Founded in 2017 and based in Centerville, Ohio, the company develops innovative, cost-effective technologies that aim to save billions of dollars annually. Its flagship products are designed to improve the accuracy of medical procedures, including contaminant-free blood culture collection for sepsis diagnosis and treatment solutions for sudden cardiac arrest. By leveraging clinical experience and the product development expertise of Pixel and Timber, True Concepts Medical Technologies creates devices that minimize human error, ensure consistent clinical delivery, and ultimately reduce healthcare costs.

SafeGuard Surgical is a medical device company focused on improving surgical outcomes and patient safety. It develops innovative, resorbable products designed to enhance colonic anastomotic healing and stability during advanced surgical procedures. These include a resorbable intraluminal stent graft and an extraluminal resorbable graft, along with anvil cap extension arms. By employing these products, SafeGuard aims to reduce surgical complications, lower healthcare costs, and minimize patient recovery time, ultimately preventing mortality and morbidity associated with surgery.

DoubleLock Healthcare specializes in developing innovative medical devices aimed at reducing healthcare-associated infections. Their primary product is a novel intravenous (IV) port and syringe system designed to enhance sterility and safety. This system, which does not require alcohol swabs or caps, is engineered to decrease healthcare costs, minimize medication errors, and improve overall patient safety in hospitals and other medical facilities.

HME Square is a digital healthcare company focused on developing medical diagnostics and devices that utilize innovative technology for health monitoring. The firm specializes in creating non-invasive glucose monitoring systems designed to measure health data accurately and continuously without the need for blood sampling or needles. By integrating photoacoustics, MEMS device technology, and deep learning into a cohesive digital data platform, HME Square aims to prevent chronic diseases and empower individuals to manage their glucose levels effectively, thereby promoting healthier lifestyles.

Aevice Health specializes in non-invasive wearable technology aimed at monitoring respiratory health in real-time. The company develops devices specifically for asthmatic patients, which track and record vital historical data related to respiratory symptoms and medication usage. This technology facilitates the early detection of cardiopulmonary issues, enabling clinicians to monitor patient responses to treatment effectively. By providing critical health insights from the comfort of home, Aevice Health enhances patient care and allows for quicker, more targeted medical interventions.

Birth By Us empowers mothers and birth attendants to customize their own birthing experience while providing caregivers with the insights and data needed to best assist their birth.

PlusVitech is a company dedicated to developing effective and safe therapeutic treatments and complementary diagnostic tests for cancer patients. It specializes in non-invasive genetic cancer detection, utilizing small molecules and monoclonal antibodies as alternatives to traditional tissue biopsies. This approach allows for earlier detection and treatment of cancers, thereby improving patient outcomes while minimizing discomfort and the time associated with invasive procedures.

Astron Medtech is a medical technology company focused on improving patient outcomes in tendon repair. The company develops disposable minimally invasive surgical devices that significantly reduce recovery time from six months to four months. By utilizing less invasive and sustainable surgical techniques, Astron Medtech aims to enhance the efficiency of surgical services while providing better options for patients undergoing tendon repair procedures.

Elythea is a technology company that develops a medical platform for obstetricians. This platform uses machine learning and deep learning algorithms to predict the risk of pregnancy complications, such as postpartum hemorrhage, cesarean section, and eclampsia, as early as the first trimester. It leverages clinical history and demographic information available at the point of care, enabling doctors to prepare for potential high-risk cases months in advance. Elythea's proprietary models have shown significantly higher sensitivity in predicting hemorrhage risk compared to current gold standard assessments, potentially reducing mortality and healthcare costs by over 90%.

ZiO Health is a biotechnology company that focuses on transforming laboratory testing through its proprietary pocket-sized technology, which allows for point-of-care diagnostics. By combining advanced biosensor technology with machine learning algorithms, ZiO Health provides real-time testing results tailored to each patient's unique profile. This innovative approach enables users to measure, test, and detect the molecular composition of various substances, facilitating personalized health insights. The company's devices aim to optimize health management and enhance patient outcomes, allowing individuals to conduct quality home diagnostics and take proactive steps in preventing illness.

Innsightful offers a comprehensive digital health solution aimed at managing and alleviating mental health challenges, particularly for students. The company develops wearable devices that monitor and detect symptoms of anxiety and stress, utilizing artificial intelligence and machine learning to provide automated, early detection of heightened stress levels. These devices integrate biometrics to give users personalized insights, fostering a deeper understanding of their mental health. Additionally, Innsightful facilitates access to therapists for tailored recommendations and progress assessments, transforming how individuals approach their mental well-being.

Ember Sleep is a company focused on improving sleep quality through its innovative sleep apnea treatment platform. The platform features medical devices designed to be more comfortable, effective, and non-invasive for the treatment of sleep apnea. By providing a novel approach to open the airway, Ember Sleep aims to enhance the well-being of patients, enabling them to feel more rested while assisting healthcare professionals in delivering better health outcomes.

IC Innovations develops disruptive technology for respiration measurement and analysis. We are focused on lowering the barriers to access to advanced respiratory assessment, in fields such as sports and healthcare.

Flagler Health is a developer of clinical decision support software that transforms clinics into virtually vertical health systems. The company offers a platform that leverages patient data and clinical guidelines to assist physicians in identifying potentially beneficial procedures that may have been overlooked. By utilizing advanced AI technologies, Flagler Health recommends optimal treatment strategies based on individual patient data, enabling healthcare providers to deliver more comprehensive care. This approach aims to improve patient outcomes and enhance the overall efficiency of healthcare delivery.

Curespec is focused on developing a medical device known as Nephrospec, aimed at addressing the interconnected challenges of chronic kidney disease and hypertension. The device is designed to preserve kidney function, thereby delaying the need for dialysis and treating high blood pressure. By providing healthcare professionals with an innovative tool, Curespec seeks to reduce the suffering associated with kidney failure and hypertension, ultimately improving patient outcomes in these prevalent health conditions.

CardMedic is a healthcare platform designed to enhance communication between healthcare staff and patients, addressing various barriers such as language differences, visual and hearing impairments, cognitive challenges, and literacy issues. The platform features a comprehensive library of digital flashcards that replicate clinical conversations on common healthcare topics. These flashcards are available in multiple formats, including multilingual options, sign language, easy-to-read text, and read-aloud capabilities. By facilitating clearer communication, CardMedic aims to improve the quality of care and reduce health inequalities, ensuring that patients can access essential healthcare information in a way that is understandable to them. The platform is accessible via smartphones, tablets, or desktops, making it a versatile tool for both patients and healthcare providers.

Welfie is a health platform designed to support K-12 schools in addressing contemporary health issues among children. It offers a comprehensive data platform that provides health data assessments and insights, enabling parents, healthcare providers, and community health leaders to make informed health decisions for children. Welfie emphasizes a whole-child approach by tracking various aspects of health, including social, emotional, and mental well-being, while also focusing on critical areas such as heart health, nutrition, fitness, and diabetes management. By equipping caregivers and educators with valuable resources, Welfie aims to enhance the overall health and wellness of students.

Patientory, Inc. is a healthcare technology company based in Atlanta, Georgia, established in 2015. It offers a health data management platform that enables individuals to securely store, manage, and share their health information. The platform empowers patients to take control of their medical records and chronic illness management while facilitating better communication and support between healthcare providers and patients. By integrating a blockchain-enabled network, Patientory streamlines access to health data, enhances care coordination, and provides insights into health outcomes. This approach aims to democratize health data ownership, reduce healthcare costs, and improve overall patient engagement and health management.

CBOH is a digital health platform that decentralizes control of health identity and data. It empowers users to control their digital health identity and share verifiable health statuses with whom they choose. It is on a mission to destigmatize health testing and eliminate the spread of transmissible infections.

juli is a digital healthcare startup founded in 2020, aimed at improving the lives of individuals with chronic conditions. The company develops an artificial intelligence-powered application that consolidates diverse healthcare data into a single platform. This application supports users dealing with various chronic health issues, such as asthma, migraines, depression, bipolar disorder, and chronic pain. By integrating data from smartphones, wearables, and self-reported information, juli enables users to self-track and manage their symptoms effectively. The founders, motivated by personal experiences with chronic conditions, leverage their expertise in big data to enhance healthcare outcomes and promote better understanding of health triggers and management strategies.

Eupnoos is a health-tech company specializing in digital healthcare solutions for lung health and disease detection. The company has developed a smartphone-based application that utilizes the device's microphone and camera to perform clinical-grade lung function tests and symptom-guided assessments. This platform enables users to screen, measure, and track the progression of lung health issues. By providing device-agnostic, API-accessible automated testing and data interpretation, Eupnoos supports both clinical and consumer-grade respiratory monitoring devices. The company's services facilitate telehealth and remote patient monitoring, empowering individuals to gain insights into their lung health and access professional healthcare guidance.

Ferrum Health, Inc. is a health technology company based in Santa Clara, California, that develops an artificial intelligence platform aimed at preventing medical errors and improving patient outcomes. The platform analyzes patient data across health systems to identify gaps in care and deploys multiple computer vision algorithms to evaluate radiologic images for commonly overlooked pathologies, such as lung nodules and fractures. Additionally, a proprietary natural language processing algorithm correlates these findings with physician notes, enabling hospital quality officers to address potentially missed diagnoses. Founded in 2017, Ferrum Health focuses on ensuring quality assurance in critical healthcare decisions, thereby enhancing the overall patient care experience through the integration of AI-driven tools.

HealthOpX specializes in developing software solutions for community-based organizations, health systems, and payers, aiming to enhance community member engagement and overall health outcomes. Their platform includes a predictive analytics tool that helps assess the risks associated with patient readmissions, emergency room visits, and morbidity. This technology supports healthcare practitioners by facilitating care coordination, improving medical adherence, and enhancing clinical experiences. Through its services, HealthOpX enables organizations to implement effective health programs and collaborate with government and health entities, ultimately providing accessible and cost-effective care to at-risk patients.

Together by Renee is a free app that uses generative AI to streamline and automate health tasks like ordering refills, booking appointments and completing forms in an easy user experience perfect for the 123 million aging Americans managing diabetes, obesity, hypertension, and more. Together measures vital signs like blood pressure via smartphone camera - with no devices or wearables required. Together requires no data entry, typing or integration to legacy systems, using just AI to automate patient-centric care coordination. 67% of Together’s first 15,000 users are over 55 years of age and Together enjoys NetPromoter score of +85.

CardMedic is a healthcare platform designed to enhance communication between healthcare staff and patients, addressing various barriers such as language differences, visual and hearing impairments, cognitive challenges, and literacy issues. The platform features a comprehensive library of digital flashcards that replicate clinical conversations on common healthcare topics. These flashcards are available in multiple formats, including multilingual options, sign language, easy-to-read text, and read-aloud capabilities. By facilitating clearer communication, CardMedic aims to improve the quality of care and reduce health inequalities, ensuring that patients can access essential healthcare information in a way that is understandable to them. The platform is accessible via smartphones, tablets, or desktops, making it a versatile tool for both patients and healthcare providers.

Ronawk is a biotechnology company that specializes in the development of T-Block technology, which produces patient-specific biologics for the treatment of diseases, including cancer, organ injuries, and burns. The company has created a proprietary method for growing primary stem cells in a three-dimensional environment, allowing these cells to retain their essential characteristics outside the body. This innovative approach enables the rapid expansion of stem cells, making them suitable for early-stage diagnostics and the repair of injured tissues. Additionally, Ronawk focuses on preserving primary cells from patients for future use in reconstructive surgeries, thereby enhancing the efficiency and density of human cell growth for tissue generation and disease modeling.

INIA Biosciences focuses on creating non-invasive medical devices that leverage sound wave technology to manage chronic inflammatory diseases. The company's innovative system combines biomarker monitoring with an ultrasound stimulator, aimed at reducing inflammation associated with transplant rejection and decreasing reliance on immunosuppressant medications. This home-administered, closed-loop monitoring system provides physicians with advanced diagnostic capabilities to improve the treatment and prevention of organ failure, ultimately enhancing patient care in chronic disease management.

Astellar Labs specializes in developing non-invasive diagnostic technology for measuring blood glucose levels without the need for finger pricks or frequent device replacements. Their technology, powered by artificial intelligence, tracks blood glucose over time, predicts trends, and provides early warnings to patients, enhancing comfort and cost-effectiveness.

WestFace Medical is a medical device company focused on enhancing vascular access procedures through innovative imaging technology. Their flagship product, SingleStick™, features a patented imaging adapter that employs optical coherence tomography (OCT) to provide real-time visualization of needle trajectories during vascular access. The system consists of a disposable handheld imaging adapter that attaches to any hollow bore needle and an OCT image processor, which displays the captured images. This technology allows clinicians to visualize anatomical markers in real-time, thereby improving clinical outcomes and patient satisfaction while potentially reducing costs associated with vascular access procedures. By offering a solution that facilitates traditional techniques with advanced imaging capabilities, WestFace Medical aims to redefine the standard of care in this critical area of healthcare.

Flourish Collective is a digital platform designed to support new and expecting families by enhancing access to maternal healthcare and wellness services. It features a marketplace that offers evidence-based products and vetted maternal wellness services, along with a funding mechanism that allows friends and family to contribute towards a positive birth and parenting experience. By providing resources for pregnancy, birth, and postpartum care, Flourish Collective aims to bridge gaps in maternal healthcare, making essential wellness services accessible to all mothers from pregnancy through motherhood.

MoviWear is a technology company that specializes in medical AI and remote monitoring solutions, primarily through its platform MoviWearMED. This platform is designed to monitor patients' vital signs in real-time, whether they are at home, in retirement facilities, or on the go. By utilizing proprietary 5G IoT NurtureWatch wearables, MoviWear can detect critical changes in health indicators such as heart rate, temperature, blood pressure, and oxygen levels, as well as alerting caregivers in case of falls. The company addresses the increasing demand for continuous health monitoring outside of traditional hospital settings, particularly for seniors. Founded in 2017, MoviWear aims to enhance patient safety and prevent health emergencies, drawing inspiration from a personal family experience. Its clientele includes health and telecommunications companies across North America, Europe, and Israel.

LIALT Laboratorio de Investigación Alternativa develops toxicological evaluations without the use of animals. LIALT replaces the use of animals through the use of three-dimensional tissues in conjunction with internationally recognized protocols that provide more specific information on the mechanisms of toxic action than that obtained in animals, offering a solution to the problem previously exposed.

Lab SD offers the EYELIKE Platform which increases access to eye health services for marginalized people through appropriate technology and task-shifting. The company provides technologies that help effectively and efficiently operate international health and international development projects to eradicate poverty.

Through the experience of 15-year skin optics research, we developed optical modules that work in conjunction with sophisicated algorithms to quantify various skin contents such as hemoglobin, bilirubin, skin collagen, skin oxidative stress, blood glucose variation, and etc. In contrast to the market available wearable optical modules that can only measure heart beat rate, our wearable module design provides much more information for personal health monitoring and thus could have multitude application scenarios with great marketing potential.

Nightingale Caring Solutions specializes in nursing care analytics aimed at enhancing the delivery of nursing services within healthcare systems. By employing advanced research techniques, big data, and machine learning, the company analyzes the relationship between individual nurses and patient outcomes. This analysis supports hospital administrators in optimizing various operational aspects, such as nurse staffing, scheduling, and nurse-patient assignments. The technology developed by Nightingale Caring Solutions enables stakeholders to visualize workforce dynamics and make informed decisions that improve both patient and nurse outcomes. Ultimately, the company focuses on creating tailored solutions that promote safety, efficiency, and cost-effective care delivery in the healthcare sector.

NurLabs develops label-free and reagent-free diagnostics to detect cancer early when it is most treatable.

ModoScript develops a B2B hardware SaaS solution focused on remote treatment monitoring and big data analytics to enhance medication and treatment protocol efficiency. The company specializes in high-cost specialty pharmaceuticals, particularly Oral Oncolytics, and aims to leverage treatment progress data to create more personalized and safer therapies. By targeting pharmaceutical companies, health insurance providers, and medical practices, ModoScript facilitates the delivery of remote treatment care for patients with cancer and other chronic conditions. Their customizable data analytics model allows for real-time assessment of treatment effectiveness while ensuring that patients can access the service at no cost. Distribution partners include mail-order specialty pharmacies and in-office integrated pharmacies. ModoScript is committed to improving patient outcomes and ensuring equitable access to high-quality care, regardless of patients' backgrounds or socioeconomic status.

Fora Health helps patients and clinicians track health and take part in shared decision-making. The company's platform links a patient-facing smartphone app with a clinical team web interface, powering remote patient monitoring and shared decision making. Fora Health is scaled to the needs of clinical teams, configuring data collected from validated ePROs and cognitive assessments, to goal tracking, medication adherence, and side effect tracking.

Yengii Biosciences develops the Galet smartphone microscope for detecting infectious illnesses such as malaria, sleeping sickness, and tuberculosis. The Galet platform is intended to do very complicated blood film analysis in a simple, portable point-of-care tool, which is now limited to high-end laboratories. Making such blood film analysis more available would allow for the early diagnosis of the most serious health concerns, such as malaria, and will save lives.

Gensor develops a virus testing platform based on the gene field-effect transistor technology.

Neurava is a company focused on developing non-invasive wearable diagnostic devices for patients with epilepsy, particularly those at risk of Sudden Unexpected Death in Epilepsy (SUDEP). The company's innovative device monitors critical biological signals related to epilepsy, providing timely alerts to caregivers and patients. By offering a reliable monitoring solution, Neurava aims to enhance patient autonomy and deliver peace of mind to families, facilitating timely intervention when necessary. The company's work lies at the intersection of medical device manufacturing and health diagnostics, addressing a significant need within the epilepsy patient community.

Enhearten is a digital health company that facilitates connections between patients, healthcare providers, and community health groups to support individuals recovering from substance use and addiction. Its platform offers remote patient monitoring and ongoing access to resources, even during relapse, to help build a stable foundation for sustained recovery.

FormaPath develops innovative laboratory tools aimed at enhancing tissue sample preparation for diagnostic purposes. The company has created an automated adipose tissue separation instrument designed to improve laboratory automation and patient care by effectively isolating lymph nodes from surrounding fat, resulting in higher yields. Additionally, FormaPath is collaborating with a prominent medical center to develop a specimen preparation system that automates the grossing process in anatomic pathology labs, thereby facilitating the detection of cancer spread. By equipping pathologists with advanced technology, FormaPath aims to provide accurate information that supports timely and reliable diagnoses for patients.

Onye is a health technology company focused on building solutions that power and add value to both patients and healthcare providers. The company's product is a mobile-first web-based electronic health record system for healthcare providers to improve their clinical and administrative workflows.

Digital Patient XP is a digital platform that reimagines the cycle of care. It provides real-time feedback on patients’ progress, recollection, engagement, and other determinants.

Afya Pamoja provides healthcare managers with actionable data and insights on the quality of service delivery.

Lambent Data specializes in creating innovative software solutions that facilitate the engagement of families and individuals in managing their health and social determinants. The company collaborates with healthcare and social service providers to enhance outcomes and operational efficiencies. Its user-friendly platform aims to improve the well-being of children and families by addressing various social determinants of health. By leveraging powerful data analytics, Lambent Data strives to support healthcare providers and social service practitioners, ultimately leading to better health outcomes while reducing overall healthcare costs.

Diamante is an Italian company founded in 2016 and headquartered in Verona, specializing in the development and manufacture of diagnostic devices for autoimmune diseases using advanced nanomaterials. The company utilizes plants as bioreactors to produce nanoparticles derived from modified plant viruses. This innovative approach facilitates the creation of new diagnostic tools and therapies aimed at addressing autoimmune diseases, particularly through techniques that involve the re-induction of these conditions. By leveraging plant-based nanotechnologies, Diamante is positioned to contribute significantly to advancements in autoimmune disease diagnosis and treatment.

BioEclosion is a biotechnology company specializing in the development of user-friendly, rapid diagnostic tools. Its core technology, Celifast, is a non-invasive method for detecting celiac disease, validated and patented. The company aims to expand this platform to other emerging diseases, using molecular biomarkers for swift identification. BioEclosion's device comprises a single-use cartridge tailored to each application and a portable, battery-operated reader, making it versatile for human and veterinary health, as well as food and environmental safety.

BestHealth4U focuses on the research and development of advanced solutions for manufacturers of class 1 medical devices. The company specializes in medical adhesive technologies that aim to prevent skin injuries, accelerate healing, and enhance overall patient health. Its innovative and environmentally friendly adhesive products are designed to safeguard patients from skin damage, discomfort, irritation, and infections by improving the attachment of bandages, dressings, and medical devices to the skin. By providing effective solutions, BestHealth4U assists healthcare providers in reducing medical adhesive-related skin injuries and promoting the well-being of patients.

Criam is a biotechnology company based in Braga, Portugal, founded in 2015. It specializes in the research and development of a medical device designed for blood type analysis and the detection of infectious diseases. The company's flagship product offers rapid and accurate testing for various conditions, including HIV, Brucella, tick fever, syphilis, mononucleosis, and meningitis. This portable device operates independently of electricity or laboratory infrastructure, making it accessible for use in diverse environments. Additionally, Criam's technology is scalable, allowing a single reader to perform multiple tests using specific cartridges and advanced computer vision algorithms. By optimizing blood testing services, Criam aims to provide timely health information and improve clinical decision-making.

Paragit Solutions specializes in the development of innovative systems for remote patient monitoring and data-driven management of movement disorders, particularly Parkinson's disease. Their flagship product, the Paragit Sleeve, utilizes a patented sEMG (electromyography) technology to capture sensitive data on muscle activation, movement, and grip force during patients' daily activities. Paragit offers two software solutions: the PD Monitor, designed for caregivers to manage Parkinson's disease through data interpretation of key motor symptoms such as rigidity and tremor, and the MD Lab, tailored for decentralized clinical trials across various movement disorders. The PD Monitor provides caregivers with visual data to enhance treatment optimization and telemedicine practices, while the MD Lab enables researchers to analyze over 20 metrics related to disease severity, facilitating comparisons and tracking trends across different patient groups. This integration of hardware and software allows for improved patient care and more efficient clinical research.

BrightCure Ltd. is a company based in London, United Kingdom, that specializes in developing probiotic-based therapies aimed at treating urinary tract infections (UTIs). Founded in 2019, BrightCure addresses the significant challenge of recurrent and difficult-to-treat UTIs, which affect a large portion of the global population, particularly women. Conventional UTI treatments often fall short in effectiveness and can lead to serious side effects, contributing to the rise of antibiotic-resistant infections. The company focuses on leveraging the natural microbiome to eliminate harmful bacteria while restoring beneficial flora. BrightCure's flagship product, a bioactive intimate cream, is designed to enhance the natural immune response and support urinary tract health. The UTI treatment market is projected to grow significantly, reflecting the urgent need for effective solutions. BrightCure has received recognition for its innovative approach, including seed investment from SOSV and accolades in various competitions, underscoring its potential impact in the healthcare sector.

Digi.Bio is a Netherlands-based company that specializes in developing software solutions for the healthcare industry, particularly in the field of cell therapies. It offers a microfluidic platform that automates repetitive and manual laboratory workflows, utilizing artificial intelligence and electrowetting technology to manipulate droplets at a microscale. This innovative approach aims to streamline multistep liquid handling applications, replacing traditional pipetting methods. Digi.Bio's platform delivers comprehensive analysis of cell therapies, evaluating their performance and outcomes at the single-cell level within 24 hours, while minimizing material waste. By enhancing automation in medical and pharmaceutical settings, Digi.Bio supports the advancement of bioengineering processes.

Paragon Pure is a food company focused on developing natural ingredients that cater to contemporary dietary needs. The firm specializes in producing a healthy and sustainable structured fat and flavor system derived from upcycled rice bran, particularly for use in alternative proteins. By leveraging expertise in flavor encapsulation, process engineering, and physical chemistry, Paragon Pure aims to create genuine ingredients that deliver natural flavors, colors, and nutrients in wholesome foods. This approach enables consumers to fully enjoy the diverse flavors of various spices while adhering to healthier eating practices.

Agamon is a healthcare intelligence platform that focuses on enhancing the management of radiology findings and follow-up recommendations. Utilizing advanced deep learning natural language processing technology, Agamon's platform automates the extraction of critical data from radiology reports, facilitating streamlined workflows, personalized communications, and monitoring of follow-up adherence. The platform effectively manages important healthcare programs, including Lung Cancer Screenings and the tracking of incidental findings such as pulmonary nodules and aortic aneurysms. By breaking down data silos and structuring unstructured data, Agamon provides physicians and researchers with valuable insights that are essential for advancing medical procedures, diagnostics, and treatment in the healthcare sector.

UpLift Health Inc., known as UpLift, is dedicated to developing a digital application aimed at treating depression through cognitive behavioral therapy (CBT). Founded in 2018 and based in Atlanta, Georgia, UpLift offers a structured program that consists of twelve weekly sessions, each lasting approximately 40 minutes. During these sessions, users engage with chatbot-guided interactions that help them learn effective coping skills. In addition to the sessions, the application provides daily tools and challenges that allow users to apply what they have learned in their everyday lives. A pilot study has demonstrated that this program can reduce symptoms of depression by 52%. UpLift's mission is to significantly impact mental health by assisting one million individuals in overcoming depression.

Tellus is a health monitoring platform focused on enhancing eldercare quality and operational efficiency. It utilizes advanced, wireless sensor technology to monitor vital signs and activity without the need for wearables or video cameras. The platform provides real-time alerts and actionable insights related to fall detection, sleep patterns, pulse, behavior, heart rate, and breathing rate. By analyzing baseline health data, Tellus enables care facilities to respond effectively during emergencies and make informed decisions to improve the well-being of their residents.

Ōmcare is a digital health company pioneering an open access, home health platform that allows healthcare organizations to extend care into the home via a secure telehealth infrastructure and integration with our patented medication dispensing technology. Ōmcare enables remote delivery of wrap around care coordination and integration of existing virtual care and remote patient care solutions and promising real medication adherence defined as right med, right time, right person. Ōmcare allows healthcare organizations to rapidly deploy a home care strategy, customized to your brand and patient needs. The product’s open architecture also allows for the integration of provider and consumer tools accelerating deployment and keeping the focus on patient outcomes. Whether it’s driving additional revenue, creating better experiences, reducing operating costs, or improving the health of the end-users, Ōmcare can be deployed either broadly at a certain market or more tactically at a specific subset of a membership group. Initial targets include the rapidly aging, complex chronic and dual populations.

Semantic Health is a Toronto-based healthcare technology company that utilizes proprietary artificial intelligence to enhance medical coding, auditing, and clinical documentation improvement processes for hospitals. The company's online medical data platform automates the extraction of medical codes and insights from patient charts, creating a real-time, actionable data layer. This disruptive data engine enables hospitals to analyze medical data more effectively, ultimately improving patient care, operational efficiencies, and the delivery of value-based care.

PainPal is a behavioral health platform specifically designed for individuals experiencing chronic pain. It offers a personalized and gamified approach to on-demand Cognitive Behavioral Therapy (CBT-CP), which has been shown to effectively reduce pain and enhance functioning. By utilizing this innovative telebehavioral health platform, PainPal provides a safe and evidence-based alternative for patients, addressing the growing concerns related to chronic pain management and the opioid crisis. The platform aims to redefine treatment possibilities for those suffering from chronic pain, making therapy more accessible and engaging.

See Yourself Health specializes in chronic care management by leveraging immersive technology, data science, and social learning to enhance health and wellness. The company offers a platform focused on diabetes treatment within a virtual environment, utilizing a peer network and a constructivist curriculum to foster engagement. By emphasizing peer support, online learning, and measurement-based care coaching, See Yourself Health aims to improve outcomes for individuals managing chronic diseases. Their approach is designed to help both healthcare professionals and patients navigate high-intensity, high-stress situations, thereby accelerating behavior change and optimizing health results.

Mosaic health data provides medical records of complete data of a patient's health across the continuum of care

Ōmcare is a digital health company pioneering an open access, home health platform that allows healthcare organizations to extend care into the home via a secure telehealth infrastructure and integration with our patented medication dispensing technology. Ōmcare enables remote delivery of wrap around care coordination and integration of existing virtual care and remote patient care solutions and promising real medication adherence defined as right med, right time, right person. Ōmcare allows healthcare organizations to rapidly deploy a home care strategy, customized to your brand and patient needs. The product’s open architecture also allows for the integration of provider and consumer tools accelerating deployment and keeping the focus on patient outcomes. Whether it’s driving additional revenue, creating better experiences, reducing operating costs, or improving the health of the end-users, Ōmcare can be deployed either broadly at a certain market or more tactically at a specific subset of a membership group. Initial targets include the rapidly aging, complex chronic and dual populations.

Litesprite, Inc. is a company based in Bellevue, Washington, that develops mobile games aimed at helping individuals manage chronic health conditions such as stress, anxiety, and depression. Its primary product, Sinasprite, is a video game designed to assist users in navigating their mental health treatment by providing resources and coping mechanisms tailored to their needs. This platform allows healthcare providers to collect and analyze data on player behavior, enabling them to identify effective strategies and improve treatment outcomes. Litesprite's innovative approach combines proven medical practices with engaging gameplay, fostering greater patient participation and support networks. The company has also been recognized for its potential impact on health management, having won an award in the Robert Wood Johnson Foundation's Games to Generate Data Challenge.

Zibrio is a balance diagnostics company based in Houston, Texas, that was established in 2017. The company specializes in a technology that utilizes insights from postural control and machine learning to detect subtle changes in balance. Originally developed from NASA technology designed for astronauts returning from space, Zibrio's device aims to empower individuals to take charge of their health. By measuring balance and weight, it helps users understand their balance profiles and offers guidance for improvement. The company's mission is to enhance health outcomes, reduce the risk of falls, and promote overall balance and well-being.

TREND Community is a healthcare organization focused on enhancing the quality of life for individuals with rare and chronic diseases. The company develops a platform that utilizes advanced analytics to extract valuable insights from social media posts, patient stories, caregiver discussions, and surveys. By analyzing this real-world data, TREND Community aims to understand diseases from the perspectives of those affected, facilitating the creation of health initiatives and enabling patients to share their experiences and receive medical advice. Additionally, TREND Community plays a role in educating patients, supporting medicine and research discoveries, and assisting individuals in developing their own natural histories.

Healium is a mental fitness tool that offers a drugless approach to managing anxiety, sleep, addiction, and burnout. The company utilizes patented technology that connects to biometric data from consumer wearables, such as smartwatches and EEG headbands, allowing users to monitor their brainwaves and heart rate. This information is used to create a reactive, immersive media experience that adapts to the user's bio-data. Healium's unique platform has been validated by eight peer-reviewed studies, demonstrating its effectiveness in reducing anxiety and improving mood within minutes. By leveraging existing sensors and devices, Healium provides a controlled virtual and augmented reality environment for users seeking to enhance their mental well-being.

Starling Medical focuses on creating a remote patient monitoring platform that facilitates at-home urine diagnostics, integrating seamlessly into everyday bathroom routines. The company is developing a healthcare device that employs mass spectroscopy-based sensors to continuously monitor changes in urine composition. This technology aims to enable early detection of chronic health issues, allowing both patients and healthcare providers to intervene promptly and potentially prevent serious complications or hospitalizations. By offering predictive insights, Starling Medical aspires to enhance health outcomes through proactive monitoring.

PREEMIEr Diagnostics is a healthcare provider focused on the health of premature infants, specifically aimed at preventing retinopathy of prematurity. The company has developed a diagnostic device that measures blood glucose levels in these vulnerable patients. This technology assists healthcare professionals in identifying premature infants who require adjustments to their glucose levels, facilitating early detection of potential health issues. By improving the management of glucose levels, PREEMIEr Diagnostics contributes to enhancing the overall health outcomes for premature infants.

Steradian Technologies is a biotech company focused on developing noninvasive and fully portable diagnostic solutions for infectious diseases. The company specializes in a rapid COVID-19 detection test that utilizes advanced photon-based technology to identify pathogens within 30 seconds. By employing focal point projection systems that replicate human eyesight, Steradian’s approach eliminates the need for traditional laboratory settings, multiple testing steps, and extensive sample preparation. This innovative method not only enhances the speed of diagnosis but also maintains high accuracy in detecting a range of bacteria, viruses, and biomarkers. By streamlining the diagnostic process, Steradian Technologies aims to revolutionize patient care and provide clinicians with rapid and precise diagnostic capabilities.

my110 is a London-based company that focuses on enhancing athlete performance through innovative health solutions. It has developed a tool designed to analyze and optimize body recovery, enabling athletes to achieve and maintain peak physical performance. The company also emphasizes a proactive approach to healthcare, utilizing decentralized methods for testing and tracking acute diseases. By integrating these strategies, my110 aims to improve overall health outcomes for athletes and individuals alike.

M de Maní develops products with more flavor and more nutrients from less refined ingredients and without harmful chemicals or hydrogenated fats. The company believes that taking care of health is crucial and should be a simple task, which is why they offer practical, delicious, and highly nutritious products.

Decentriq is a confidential data collaboration platform designed to facilitate secure access and analysis of sensitive data while maintaining strict confidentiality. It serves both data scientists and business users, allowing them to leverage data clean rooms to analyze sensitive information without the need to share it directly. Utilizing advanced privacy technologies and hardware cryptography, Decentriq ensures that data remains encrypted throughout its lifecycle, preventing access by unauthorized parties, including cloud providers. The platform enables enterprises to scale their data collaborations across organizational boundaries, unlocking value from data that would otherwise be too sensitive to utilize. Its features support smooth collaboration workflows, flexible analysis, and interoperability with other technologies, making it particularly valuable for industries that prioritize privacy and compliance, such as media, healthcare, banking, and the public sector.

Byteflies is a Belgian-American wearable health company focused on developing innovative health applications through advanced technology. With offices in Antwerp, Belgium, and the San Francisco Bay Area, the company is strategically positioned near major life sciences and clinical research centers as well as the heart of digital innovation. Byteflies specializes in a wearable component sensor dot that records various biopotential signals, muscle activity, eye movement, and activity-related signals using an integrated inertial measurement unit. This technology is designed to assist pharmaceutical companies, researchers, and technology firms in transforming healthcare and enhancing patient outcomes. Byteflies aims to revolutionize healthcare by meticulously monitoring vital signs and leveraging data-driven insights.

Grapheal is a Medtech startup focused on developing embedded and wearable biosensors that leverage graphene transistors for enhanced functionality. Their devices are designed to be minimalistic and digital, enabling the dosing of biomarkers and detection of pathogens through a smartphone interface. By integrating advanced sensing nanomaterials with wireless connectivity and data analysis capabilities, Grapheal's biosensors facilitate field diagnostics and remote patient monitoring. This approach aims to make healthcare more accessible and accurate, allowing medical professionals to effectively monitor patient progress and healing.

Equine Smartbit, LLC is a company based in Saint Louis, Missouri, that specializes in the design and manufacture of a health monitoring device for horses called SmartBit. Established in 2016, the company creates technology that allows horse owners, trainers, and veterinarians to monitor and analyze the wellness, health, and performance of horses in real-time. The SmartBit device utilizes biometric sensors to capture vital signs, including temperature, heart rate, and blood oxygen saturation, by assessing data through a non-invasive system. This technology not only matches performance metrics with a horse's biometrics but also sends alerts when the horse's physical condition is suboptimal. Additionally, Equine Smartbit provides software tools to further assist in understanding the health and training of horses, thus enhancing their overall care and performance.

EyeTrac has developed novel face guard technology for contact sports, which can detect concussions accurately on the field in real-time. The incidence of concussions and traumatic brain injury (TBI) has reached epidemic proportions in sports. There is a growing need on the playing field for a head-worn device that can objectively assess head trauma in real-time. This innovative technology is designed to meet the specific needs of athletes participating in contact sports and address limitations of currently available methods of evaluation. It will provide immediate accessibility with diagnostic accuracy for concussions.

Microbial Pulse Diagnostics is developing and deploying an innovative NIST technology for the rapid measurement of antimicrobial susceptibility. This technology “takes the pulse” of bacterial cells, sensing changes in their metabolism, motility, and growth after exposure to an effective antibiotic.

UDoTest is a Boston-based B2B disease testing platform established in 2017 by Allison Martin. The company specializes in self-sampling screening test kits designed for early detection of various diseases, including colon cancer, HPV, and STDs. By offering convenient at-home testing solutions, UDoTest aims to improve the wellness experience and enhance the quality of disease screening. Its human-centered platform facilitates accurate pathology tests, allowing patients to access personalized services that simplify the screening process.

Hera - Mi is Specialized in digital medical imaging applied to breast cancer.Hera-MI has developed clinical decision support solutions to help improve early-stage breast cancer detection. Our solutions will improve the quality and accuracy of breast cancer diagnosis while decreasing radiologists’ interpretation time. Patients will be treated more quickly, offering them a better chance of remission. Hera-MI has developed Breast-SlimView, a clinical decision support software based on artificial intelligence and image processing for breast cancer diagnosis. Our partner, Fujifilm is selling Breast-SlimView in France and in the Overseas Territories of France (DROM/TOM). Breast-SlimView is also available for sale all over the world.

Walk With Path develops wearable products aimed at improving mobility and health for patients, particularly those affected by diabetes and movement disorders. The company’s flagship offering is a smart insole equipped with biofeedback technology and sensors, designed to enhance balance and prevent complications such as foot ulcers in diabetic patients. Additionally, Walk With Path has introduced Path Finder, a specialized shoe designed for individuals with Parkinson's disease to alleviate the 'freezing of gait' phenomenon, which can leave users feeling immobilized. Path Finder is recognized as a medical device with supporting evidence published in Neurology. The company's products not only provide therapeutic benefits but also offer data insights and analytics for both end users and healthcare professionals, facilitating gait analysis and promoting better mobility in various populations.

PROSPERiA is a social impact enterprise originating from the MIT Media Lab, focused on enhancing the early detection and treatment of chronic diseases in emerging markets through innovative artificial intelligence solutions. The company develops AI-driven technologies that facilitate the screening of conditions such as diabetes and hypertension, along with their associated visual complications. Their approach includes risk assessment calculators, non-invasive fundus cameras, and retinal image analysis, complemented by personalized recommendations for healthcare providers. This enables physicians to effectively prevent diabetes and its complications, ultimately aiming to improve health outcomes in underserved populations.

Thinks Works is an early-stage biomedical company focused on improving the treatment of adolescent scoliosis, a severe spinal curvature in children. Founded by Dr. Ryan C. Murdock, the company aims to address the limitations of current treatment methods, which involve custom-made hard plastic braces that can be uncomfortable and have poor patient compliance. Thinks Works is developing a novel, flexible brace that promises enhanced patient comfort, improved compliance, and better treatment outcomes at a lower total cost. The device also provides real-time treatment data, enabling healthcare providers to monitor and adjust treatment plans as needed.

TomoWave is a company focused on developing innovative imaging technologies for clinical medicine and preclinical research. Utilizing its proprietary optoacoustic and laser ultrasonic imaging modalities, TomoWave aims to enhance cancer detection, guide medical interventions, and monitor the effectiveness of cancer therapies. The company's technology, which captures images by "listening to the sound of light," allows for highly detailed visualization of tissues, particularly in relation to vascular and blood-related conditions. Founded by Dr. Alexander Oraevsky, a pioneer in biomedical optoacoustics, TomoWave has a strong emphasis on generating intellectual property and advancing it from concept to validated clinical prototypes. The company is committed to bringing its technologies to market through appropriate regulatory certifications, thus contributing to improved diagnostic capabilities in healthcare.

Illuminate Health App is a home health technology company. They offer advanced technology that allows them to perform a complete health exam, and encryption ensures data is protected at the highest possible levels.

Simply Speak is a digital health company founded in 2019 and based in New York, New York. It specializes in developing an artificial intelligence platform that assists physicians in documenting telehealth encounters with patients. By leveraging conversational AI, Simply Speak's platform extracts meaningful medical data from interactions and automatically integrates this information into electronic medical records. This functionality not only streamlines the documentation process but also enhances the physician-patient relationship and boosts overall productivity within medical practices.

Pegwin is a healthcare software company that focuses on improving patient safety through its platform, KBCore. This system employs predictive technology to enhance communication among doctors, nurses, and staff while also reducing costs. Pegwin's enterprise data management platform provides real-time clinical tools that facilitate hospital rounds and offer meaningful insights for quality improvement. Additionally, it captures data to streamline risk management functions, helping healthcare organizations analyze patient safety information. By identifying active threats, Pegwin's solutions aim to predict and prevent potential harm, ultimately enabling better and safer patient care processes.

Crosscope is a medical AI software company focused on enhancing cancer diagnosis through advanced deep learning technology. It has developed a digital pathology imaging platform that facilitates the extraction of medical image information and supports precision medicine. By streamlining and accelerating pathology lab processes, Crosscope's platform improves interoperability, storage, image management, and collaboration among pathologists. This innovation enables more precise cancer diagnoses, ultimately enhancing workflow efficiency and patient outcomes.