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Innsightful develops wearable devices that monitor and detect anxiety and stress symptoms using AI and machine learning. Their solution integrates biometrics for early detection and provides access to therapists for personalized recommendations, empowering users to understand and manage their mental health.

Valence Vibrations develops AI-powered emotion analytics software that provides real-time insights into customer emotions during conversations. This tool aims to enhance emotional perception across diverse neurotypes, languages, communication styles, and cultures.

Flourish Science is a digital mental health organization that was founded in order to deliver personalized and community-oriented well-being knowledge and practices based on social psychology, positive psychology, and behavioral science.

Enrichly is an online educational platform focused on youth development, aiming to cultivate essential life skills and promote mental well-being among young people. The platform offers a variety of resources, including social skills-building workshops and virtual courses, designed to enhance students' confidence and teach them critical techniques for stress management, conflict resolution, and building healthy relationships. Utilizing deep learning, artificial intelligence, and data analytics, Enrichly's curriculum seeks to provide young individuals with the tools necessary to navigate life's challenges and prevent issues such as teen pregnancy, violent behavior, poverty, self-neglect, and suicide. By fostering personal growth and resilience, Enrichly strives to pave the way for a more successful and fulfilling future for youth.

InnoPsych is a mental health platform that seeks to reduce racial disparities in mental healthcare. It provides a national directory of therapists of color, mental health programming designed to promote open dialogue about mental wellness within BIPOC communities, and wellness products that teach emotional regulation strategies.

juli is a digital healthcare startup founded in 2020, aimed at improving the lives of individuals with chronic conditions. The company develops an artificial intelligence-powered application that consolidates diverse healthcare data into a single platform. This application supports users dealing with various chronic health issues, such as asthma, migraines, depression, bipolar disorder, and chronic pain. By integrating data from smartphones, wearables, and self-reported information, juli enables users to self-track and manage their symptoms effectively. The founders, motivated by personal experiences with chronic conditions, leverage their expertise in big data to enhance healthcare outcomes and promote better understanding of health triggers and management strategies.

Opeeka develops AI-based mental health assessment software for healthcare providers. Its platform transforms assessment data into personalized treatment plans, enabling agencies to deliver person-centered care and track patient progress.

Kintsugi develops voice biomarker software and mental health infrastructure that detects signs of depression and anxiety from short clips of free-form speech. The platform aims to help clinicians validate biomarkers and identify mental health conditions, enabling medical practitioners to close care gaps in risk-bearing health systems and save time and lives.

Canopie is a mental health care company focused on addressing maternal depression and anxiety through a digital platform. The platform offers customized, audio-based programs and automated coaching that utilize clinically validated therapeutic techniques, including adaptations of cognitive behavioral therapy and compassion-focused treatment. By collaborating with cities, payers, health systems, and healthcare providers, Canopie aims to deliver effective and affordable care for mothers, overcoming barriers such as cost, scheduling, time, and stigma. The company's innovative approach is designed to support pregnant women and new mothers in preventing and treating common mental health challenges, making it a scalable solution in maternal mental health care.

SageSurfer operates a mental healthcare platform designed to empower individuals in overcoming behavioral health challenges by fostering collaboration among their caregivers. The platform facilitates comprehensive, coordinated, and outcome-driven personalized care for mental health and addiction treatment. It enables consumers to actively participate in their care planning, ensuring they have a stronger voice in their treatment process. By centering the consumer in the recovery plan and providing access to their entire care team, SageSurfer aims to create a supportive healthcare environment where individuals are not alone in their journey towards recovery and can easily access help when needed.

Habits AI focuses on enhancing well-being within communities and workplaces by addressing lifestyle-related health issues and mental health challenges. The company offers a corporate well-being platform that integrates a virtual coach, an AI-driven chatbot, behavioral science principles, and gamification techniques. This innovative approach allows organizations to foster healthier workplace cultures, ultimately improving employee engagement, productivity, loyalty, and overall health. By providing scalable solutions, Habits AI aims to create happier and more productive environments for individuals and organizations alike.

Enhearten is a digital health company that connects patients, healthcare providers, and community health groups to facilitate recovery from substance use and addiction. Its platform supports the entire recovery process, offering remote patient monitoring and continuous access to resources, even during relapse. By building bridges among stakeholders, Enhearten helps individuals establish a stable foundation for sustained recovery.

Goaceit is a developer of a personalized, interactive web application aimed at enhancing the mental performance of users, particularly students aged 15 to 25. The platform addresses critical soft skills, such as self-awareness, self-confidence, and stress management, which are essential for success and well-being, especially during high-pressure situations like major exams. Utilizing psychology tools and machine learning, Goaceit's cloud-based solution equips users with the tools necessary to cultivate mental toughness and confidence, enabling them to navigate performance challenges effectively. The focus on developing these skills helps users cope with acute stress and enhances their overall performance in various aspects of life.

Violetta is a technology platform that utilizes a chatbot to address and measure acts of violence, an often overlooked issue. The platform connects users to psychological and legal assistance while promoting awareness of violence-related topics. By employing natural language processing models, Violetta provides a user-friendly and adaptable tool designed to foster safer relationships. Its innovative approach aims to enhance digital confidence and create a supportive environment for individuals seeking help, ultimately contributing to the prevention of violence.

Butterflly Health is a Los Angeles-based company founded in 2019 that offers a cloud-based telehealth platform focused on behavioral health and autism. The platform connects individuals with therapists and experts while providing personalized self-help resources and educational content. Additionally, it features a social network that links users with similar experiences, fostering a supportive community. By addressing both the psychological and social factors affecting mental health, Butterflly Health aims to enhance patient outcomes and promote overall well-being. The company's commitment to improving access to mental health services aligns with its goal of supporting historically marginalized communities.

UpLift Health Inc., based in Atlanta, Georgia, specializes in developing a digital application aimed at treating depression through cognitive behavioral therapy (CBT). Founded in 2018, the company offers a structured program that consists of twelve weekly sessions, each lasting approximately 40 minutes, designed to teach users effective coping skills. The application incorporates chatbot-guided interactions, allowing users to engage with mental exercises and receive feedback. Additionally, it provides daily tools for users to apply learned skills in their everyday lives. Preliminary research indicates that UpLift's program can significantly reduce symptoms of depression, with a reported reduction of 52% in pilot studies. The company is focused on its mission to assist one million individuals in overcoming depression.

PainPal is a behavioral health platform specifically designed for individuals suffering from chronic pain. The company offers a telebehavioral health solution that delivers personalized, gamified, and on-demand Cognitive Behavioral Therapy for Chronic Pain (CBT-CP). This innovative approach aims to provide effective treatment and counseling that has been shown to reduce pain and improve overall functioning. By focusing on evidence-based methods, PainPal presents a safe and cost-effective alternative to traditional pain management strategies, addressing the significant challenges posed by the chronic pain and opioid crises.

Litesprite, Inc. is a Bellevue, Washington-based company that develops mobile games aimed at helping individuals manage chronic health conditions, particularly stress, anxiety, and depression. Its flagship product, Sinasprite, is a video game designed to guide users through prescribed mental health treatments, enabling them to track their progress and engage with coping mechanisms in real time. The platform provides valuable data to clinicians, allowing them to understand the effectiveness of various treatment options for their patients. Litesprite's innovative approach combines proven medical treatments with interactive gaming to enhance patient engagement and facilitate communication between patients and healthcare providers. The company aims to create a suite of games addressing various health conditions, leveraging the emotional engagement of gaming to promote better health outcomes. Since its incorporation in 2013, Litesprite has been recognized for its potential to make a significant impact in healthcare, winning accolades such as the Robert Wood Johnson Foundation's Games to Generate Data Challenge.

Butterflly Health is a Los Angeles-based company founded in 2019 that offers a cloud-based telehealth platform focused on behavioral health and autism. The platform connects individuals with therapists and experts while providing personalized self-help resources and educational content. Additionally, it features a social network that links users with similar experiences, fostering a supportive community. By addressing both the psychological and social factors affecting mental health, Butterflly Health aims to enhance patient outcomes and promote overall well-being. The company's commitment to improving access to mental health services aligns with its goal of supporting historically marginalized communities.

Healium is a technology company that develops mental fitness tools and immersive, bio-data-driven experiences to support self-management of anxiety, sleep issues, burnout, and overall well-being. The platform links real-time biometric data from wearables such as heart rate and brain activity via EEG headbands to personalized video or VR assets, producing reactive media escapes controlled by the user’s physiology. By integrating wearable devices and sensors, Healium delivers data-driven content that adapts to the user in real time, aiming to reduce anxiety, improve mood, and build resilience for individuals and organizations. Peer-reviewed studies have reported rapid mood benefits and anxiety reduction in as little as four minutes.

Karuna Health, Inc. is a healthcare technology company that specializes in developing a patient engagement and task management platform designed to improve communication between healthcare providers and patients. Founded in 2018 and headquartered in San Francisco, California, Karuna's platform automates essential patient care management tasks, enabling health guides to assist patients with appointment reminders, health status updates, and communication with care managers. It offers a comprehensive suite of tools that facilitate scheduling, transportation organization, and the secure exchange of information, all while ensuring compliance with HIPAA regulations. By integrating workflow and automation, Karuna Health aims to enhance the patient experience and streamline interactions among patients, their families, and healthcare teams.

WorkingWell is a research-based, feasibility-tested mobile app to help people with mental illness succeed at and sustain employment. WW users set and achieve goals, establish routines, learn to get along with others and develop coping skills contributing to workplace success and tenure. WW fills the gap between what we know about mental illness and employment and what we do about it, to enhance individual outcomes and reduce employer/employee assistance, a state agency, and provider costs.

Marigold Health operates a social network community platform that provides AI-augmented chat support groups designed to assist individuals with behavioral health needs. By facilitating anonymous text-based group therapies, the company enables patients dealing with mental health and substance use conditions to connect and support one another. These support groups are complemented by the involvement of recovery coaches who help participants formulate personalized recovery plans. Marigold Health partners with treatment providers and managed care organizations within the Medicaid market, aiming to enhance patient engagement while allowing care teams to manage increased capacity effectively. Through its innovative approach, the company offers on-demand, stigma-free support for individuals seeking to improve their mental health.

Limbix is a company dedicated to developing prescription digital therapeutics for adolescent mental health. Their flagship product, SparkRx, is an evidence-based, clinically validated tool designed to treat depression and anxiety in teenagers. Limbix combines clinical expertise with technological innovation to deliver effective mental health treatments.

Marigold Health operates a social network community platform that provides AI-augmented chat support groups designed to assist individuals with behavioral health needs. By facilitating anonymous text-based group therapies, the company enables patients dealing with mental health and substance use conditions to connect and support one another. These support groups are complemented by the involvement of recovery coaches who help participants formulate personalized recovery plans. Marigold Health partners with treatment providers and managed care organizations within the Medicaid market, aiming to enhance patient engagement while allowing care teams to manage increased capacity effectively. Through its innovative approach, the company offers on-demand, stigma-free support for individuals seeking to improve their mental health.

WorkingWell is a research-based, feasibility-tested mobile app to help people with mental illness succeed at and sustain employment. WW users set and achieve goals, establish routines, learn to get along with others and develop coping skills contributing to workplace success and tenure. WW fills the gap between what we know about mental illness and employment and what we do about it, to enhance individual outcomes and reduce employer/employee assistance, a state agency, and provider costs.

Eleos Health offers automated healthcare technology solutions. Its AI-powered Speech-to-Insights system aids clinicians in making decisions swiftly, ensuring personalized, efficient, and cost-effective patient care.

Karuna Health, Inc. is a healthcare technology company that specializes in developing a patient engagement and task management platform designed to improve communication between healthcare providers and patients. Founded in 2018 and headquartered in San Francisco, California, Karuna's platform automates essential patient care management tasks, enabling health guides to assist patients with appointment reminders, health status updates, and communication with care managers. It offers a comprehensive suite of tools that facilitate scheduling, transportation organization, and the secure exchange of information, all while ensuring compliance with HIPAA regulations. By integrating workflow and automation, Karuna Health aims to enhance the patient experience and streamline interactions among patients, their families, and healthcare teams.

PraeSpero Farms operates a residential community focused on providing recovery support for individuals experiencing homelessness and substance use disorder. The organization delivers compassionate, individualized assistance aimed at facilitating lasting personal recovery and enhancing community safety. Residents have access to essential resources, including stable housing, care coordination, and skill training. The community is centered around a working, sustainable farm, which serves as an effective environment for both personal development and community reintegration. Through its initiatives, PraeSpero Farms seeks to empower individuals, equipping them with the tools necessary for a successful transition back into society.

HIGH5 Test offers a free strengths assessment platform aimed at helping individuals identify their unique talents. By guiding users in discovering their inherent strengths, the platform promotes a life filled with happiness and fulfillment. The test is designed for both individuals and groups, facilitating personal and career planning by enabling users to recognize what they are naturally good at. This focus on personal strengths not only enhances life satisfaction but also contributes to improved mental health outcomes.

Rezilient is a mental health coaching platform designed to support family caregivers of individuals with dementia and Alzheimer's, addressing the chronic stress and burnout they often experience. With over 8 million unpaid family caregivers in the United States—a number that continues to rise due to an aging population—Rezilient offers a personalized, science-based app that connects caregivers with trained coaches. The platform facilitates communication through video, voice, and text, allowing caregivers to receive real-time support and guidance as they develop essential skills and emotional resilience. Additionally, advanced AI and sentiment analysis are employed to provide predictive interventions, enhancing caregiver well-being. Research indicates that Rezilient's approach can significantly increase the likelihood of dementia patients remaining at home, leading to substantial savings for employers, insurers, and states by reducing long-term care costs.

Lumme Inc. is a company that specializes in developing an addiction treatment platform that integrates wearable technology, machine learning, and behavioral psychology. Founded in 2014 and based in Amherst, Massachusetts, the platform is designed to function as a personal therapist, providing timely assistance to users. By utilizing sensors on smartphones and smartwatches, Lumme's technology detects, predicts, and prevents behaviors that negatively impact health, specifically targeting addictions to smoking, alcohol, and unhealthy diets. The company's innovative passive gesture recognition technology alleviates the challenges associated with self-monitoring, making it easier for users to manage their behaviors. Lumme Inc. markets its platform to health insurance companies and corporations, aiming to enhance wellness and support addiction recovery.

Valera Health, founded in 2015, operates a behavioral healthcare platform that integrates digital technology and data science with personalized clinical services. The company focuses on delivering comprehensive mental health care to individuals experiencing a range of conditions, from mild issues like depression to more severe disorders such as schizophrenia. By combining therapy and medication with advanced technology, Valera Health aims to provide efficient access to mental health services, particularly for hard-to-reach populations. This approach not only enhances patient outcomes but also facilitates continuous connectivity between patients and their care teams, thereby redefining the standards of high-performing mental healthcare.

The Mighty is a digital health community designed to empower and connect individuals who are facing health challenges and disabilities. The platform provides a space for users to share stories and videos of their personal experiences with disability, disease, and mental illness. This sharing enables users to connect with others who have similar experiences, fostering a supportive environment that promotes positive energy and mutual understanding.

EBT Medical, Inc. is a clinical-stage company based in Boston, Massachusetts, with an additional office in Toronto, Canada. Founded in 2014, the company specializes in developing innovative, non-invasive neuromodulation therapies aimed at treating pelvic health disorders, particularly focusing on patients with overactive bladder. EBT Medical's technology is centered on the Saphenous nerve and is designed to provide discreet treatment options that enable patients to restore pelvic health function without the side effects typically associated with conventional therapies. The company emerged from scientific discoveries made at the University of Toronto and has benefited from a startup incubation program that has fostered numerous successful ventures in the past decade.

HIGH5 Test offers a free strengths assessment platform aimed at helping individuals identify their unique talents. By guiding users in discovering their inherent strengths, the platform promotes a life filled with happiness and fulfillment. The test is designed for both individuals and groups, facilitating personal and career planning by enabling users to recognize what they are naturally good at. This focus on personal strengths not only enhances life satisfaction but also contributes to improved mental health outcomes.

Pilleve is a company focused on addressing the critical issue of opioid misuse and addiction, which has significantly impacted many Americans. By providing a remote monitoring system, Pilleve aims to reduce the risks associated with opioid prescriptions through real-time data collection and behavioral analysis. Their solution features an integrated pill bottle and a corresponding smartphone application that securely dispenses medication while monitoring patient intake. Patients must use biometric scanners or passwords to access their prescriptions, and they are prompted to report their pain levels and mood before dispensing medication. This process allows for the early detection of problematic behaviors, enabling healthcare providers to intervene promptly if patients exceed recommended dosages. By facilitating communication between patients and their physicians through electronic health records, Pilleve strives to improve patient safety and care, ultimately reducing the social and financial burdens tied to opioid addiction for patients and their families.

BabyNoggin is a mental health screening application designed to empower parents to monitor their children's development using evidence-based tools. The application facilitates self-screening for developmental and mental health concerns, aligning with the recommendations of the American Academy of Pediatrics. It enables parents to track their children's progress and automatically scores the screening results, making them easily accessible through electronic medical record systems. Additionally, BabyNoggin assists in referring children who may need intervention services to appropriate providers, thereby helping to identify and support those at risk of developmental delays.

HealthRhythms develops a digital platform that assesses and monitors mental health conditions using deep machine learning and predictive analytics. Its solution offers real-time behavioral monitoring and personalized interventions, enabling healthcare providers to accurately measure mental health status and deliver timely care.

Marigold Health operates a social network community platform that provides AI-augmented chat support groups designed to assist individuals with behavioral health needs. By facilitating anonymous text-based group therapies, the company enables patients dealing with mental health and substance use conditions to connect and support one another. These support groups are complemented by the involvement of recovery coaches who help participants formulate personalized recovery plans. Marigold Health partners with treatment providers and managed care organizations within the Medicaid market, aiming to enhance patient engagement while allowing care teams to manage increased capacity effectively. Through its innovative approach, the company offers on-demand, stigma-free support for individuals seeking to improve their mental health.

Girls Health Champions is an innovative, peer-to-peer education model where adolescent girls in India are trained to directly educate their peers about these important health topics, including nutrition, mental health, gender-based violence, menstruation, and reproductive health. Their peer educators ("Champions") are trained in focused curriculum which were created in partnership with leading pediatricians, psychiatrists, obstetricians and gynecologists, educational specialists, and school teachers in both the United States and India.

ReachMore application that treats anxiety created by trauma events.

Mightier is a Boston-based company that develops bioresponsive video games and a family program designed to help children regulate emotions. The platform pairs gameplay with a biofeedback heart rate monitor to adjust game difficulty, encouraging kids to stay calm and in control while learning to recognize and manage emotions in daily life. Created through collaboration with Boston Children's Hospital and Harvard Medical School, Mightier aims to address behavioral and emotional challenges by teaching real-time emotion regulation skills. Founded in 2016, the company offers a program that integrates mind-body signals into interactive experiences, enabling children to practice emotional control through engaging, age-appropriate games.

Mightier is a Boston-based company that develops bioresponsive video games and a family program designed to help children regulate emotions. The platform pairs gameplay with a biofeedback heart rate monitor to adjust game difficulty, encouraging kids to stay calm and in control while learning to recognize and manage emotions in daily life. Created through collaboration with Boston Children's Hospital and Harvard Medical School, Mightier aims to address behavioral and emotional challenges by teaching real-time emotion regulation skills. Founded in 2016, the company offers a program that integrates mind-body signals into interactive experiences, enabling children to practice emotional control through engaging, age-appropriate games.

Spriteli is a digital health company which aims to reduce anxiety and elevate mood levels of our users through daily, 2 minute, video consultations. The video consultations are performed by a network of trained coaches. The calls consist of proprietary activities based on Mindfulness, Affirmation and CBT techniques. Initial beta results indicate we can improve outcomes and lower costs of traditional mental health delivery options. Currently collaborating with a major Boston Hospital.

Yana is a chatbot specializing in mental health support. It employs Cognitive-Behavioral Therapy techniques to accompany individuals dealing with anxiety and depression. Yana evaluates users' moods daily, facilitates conversations around these moods, and connects users with crisis hotlines or professionals for further assistance.

Myndlift Ltd., established in 2014 and headquartered in Tel Aviv, Israel, specializes in developing remote neurofeedback technology for mental health care. The company combines neurotechnology, behavioral psychology, and human care to provide a convenient at-home solution for users to interact with experienced practitioners. Myndlift's technology measures brain wave activity through EEG metrics, offering gamified exercises based on evidence-based techniques. With tens of thousands of individual users and hundreds of mental health providers, the company has positioned itself as the leading solution in its field, particularly for individuals with ADHD seeking to improve concentration.

Semafores is a developer of a mobile application designed to assist caregivers in navigating the complexities of family caregiving. The application provides an intuitive platform that encourages active involvement from family and friends, facilitating better organization, motivation, and connection among caregivers and their support networks. By utilizing user-friendly wizards, Semafores aims to simplify the caregiving process, making it easier for users to manage tasks, adhere to goals, and maintain engagement in their caregiving roles. The company's focus on creating a supportive environment reflects its belief that effective caregiving is a collaborative effort, enhancing the overall experience for both caregivers and their loved ones.

Spill is a confidential online platform facilitating peer-to-peer life advice sharing, primarily among college students worldwide. Users anonymously "spill" their experiences or challenges, receiving support and guidance from others who've faced similar situations. The site encourages active participation through a points system, with top contributors earning recognition akin to renowned advice columnists like Dear Abby. Spill has expanded its user base to include high school students, adults, military veterans, and entrepreneurs, operating in over 150 colleges across the US and 13 countries globally.

Ginger.io, Inc. is a digital mental health provider that offers a behavioral analytics platform designed to deliver on-demand mental healthcare via mobile devices. Founded in 2010 and headquartered in San Francisco, California, the platform connects users with a team of behavioral health coaches, therapists, and psychiatrists, facilitating personalized care accessible 24/7. Users can collect and analyze both passive and active behavioral data, enabling the identification of health insights and deviations from normal behavior. This service is utilized by a wide range of clients, including researchers, healthcare providers, and millions of employees through partnerships with leading employers and health plans. Ginger's approach focuses on providing immediate support and evidence-based interventions for individuals experiencing mental health challenges such as depression and anxiety.