MBX Capital

Arine optimizes medications and improves human health through data-driven clinical services. Arine focuses on improved outcomes and lower cost of care for patients. They partner world class data scientists and engineers with expert clinicians to develop and deliver meaningful clinical service programs. They deliver the right intervention, for the right patient, at the right time. They guide patients as they progress through their journey. They focus on outcomes. Your success is their success. They take an evidence-based approach to patient health management to drive clinical results.

SmileMD is an on-site anesthesia service company bringing anesthesia care teams and logistics to optimize the venue for surgeries. It provides anesthesia to pediatric and adult dental practices in their office setting, reducing anxiety and increasing access to care for thousands of patients each year. They utilize the same safety processes and procedures as hospitals, and our anesthesia care team allows us to provide the highest quality patient care efficiently and safely.

OFFOR Health is an on-site care delivery platform that utilizes existing capacity medical offices, dental offices, etc to accelerate surgery backlogs, provide accessibility, and improve outcomes for Medicaid patients.OFFER Health provides accessible pediatric dental anesthesia, and we are expanding into other verticals such as Mobile Integrated Healthcare community paramedicine, dental-driven primary care, vaccinations, etc.

Atlas Labs is a streamline patient enrollment in external programs to convert uncompensated care to revenue and reimbursements.Automate internal financial assistance for those that do not qualify. Help patients manage their out-of-pocket responsibility – all while improving margins, demonstrating higher levels of compliance, and meeting community needs.

Smiles.ai leverages proprietary technology and expert healthcare professionals to provide access to high-quality and cost-effective dental care products and services.

Contraline is developing the first long-lasting, non-hormonal, reversible contraceptive for men

Mae is a women's health care center providing pregnancy and postpartum support, tailored to women's needs. Mae is establishing a world in which high-quality, proactive care is the norm. Mae improves the quality of care for Black women by providing a trusted, digital-first health platform.

Care Revolutions is a marketplace for healthcare staff, an online technology platform where Hospitals and Outpatient facilities can directly access per diem medical staff. No vendors, no agencies, no middlemen. Care Revolutions fill empty shifts faster, lowers overall staffing costs, and increase trust and quality of patient care. Hospitals and outpatient facilities book professionals daily to complement their own float pool, increase shift fill rates and maintain safe nurse-to-patient ratios. Care Revolutions is funded by Y Combinator (S16) and an extraordinary group of business angels including several Y Combinator partners and alumni.

Vital Bio is reimagining lab testing to enable radically accessible care. Vital Bio is designing a new generation of tools to empower patients in monitoring health and managing the disease.

ixlayer is an industry leader in the health-tech ecosystem, providing innovative solutions for enabling health systems, payors, biopharma, and health-focused companies to offer health testing in a virtual environment. The ixlayer platform delivers end-to-end solutions for the technical, security, regulatory, and user experience components of complex health testing. As the industry shifts to remote and virtual care options, ixlayer is powering patient engagement and preventative health strategies through virtual health testing, at scale. The ixlayer solution can be added to existing patient engagement platforms and patient portals to enable real time health and wellness lab testing. Founded in 2018, ixlayer currently supports millions of patients and has launched hundreds of testing programs for large organizations, health systems and every level of the government.

AmacaThera is a clinical-stage biotechnology company developing a novel drug delivery platform to improve patient outcomes across multiple therapeutic areas, including post‑surgical pain management, cancer, and other hard‑to‑reach target areas. AmacaThera is developing combination products at the interface of biomaterials and pharmaceuticals.

Concert Health focuses on building an integrated behavioral health system. The company starts by helping medical groups integrate behavioral health services into their practices. It specializes in the fields of information technology, medical, and health care. It was founded in 2016 and headquartered in San Diego, California.

Earli is a developer of cancer treatment devices designed to search for natural biomarkers. The company's mission is to make cancer a benign experience. Cancers are detected early when they are homogeneous; and then located early, so they can be treated when the chances of survival are multiple times higher. Rather than rely on biomarkers that cancer may - or often may not - naturally provide, Earli's technology forces cancer cells to make a synthetic, non-human biomarker using a novel gene therapy approach called Synthetic Biopsy. The early cancer is then visible in a PET scanner. The same platform is also usable for therapeutics.

SecureAire is a developer of an active particle control technology used to increase the overall filtration efficiency. Its technology removes small critical particles, such as bacteria, viruses, allergens, TVOC, gasses, and odors indoors by reducing or eliminating harmful particles, enabling hospitals, commercial buildings, and homes to improve air quality, prevent sick building syndrome, and the spread of dangerous airborne pathogens.

Koneksa Health is a healthcare data analytics company that helps researchers incorporate emerging technologies (bio-sensors, activity trackers, mobile-based questionnaires, etc.) into their clinical studies. Their Koneksa Compare software dashboard enables the collection, visualization, and analysis of these patient-generated data sets. Koneksa currently supports academic and life sciences researchers, expands the universe of data that can be analyzed while also removing subjective characteristics from clinical endpoints. It was founded in 2015 and is based in New York, United States.

Atlas Labs is a streamline patient enrollment in external programs to convert uncompensated care to revenue and reimbursements.Automate internal financial assistance for those that do not qualify. Help patients manage their out-of-pocket responsibility – all while improving margins, demonstrating higher levels of compliance, and meeting community needs.

Brightside is inventing a new category of financial health company -- Financial Care. Brightside provides employers with a complete platform of financial solutions, focused on the 2/3 of workers who are living paycheck to paycheck and driving the cost of poor financial health (turnover, healthcare costs, productivity, DEI, and safety) for companies with front-line workers. Brightside combines these solutions with tech-powered financial assistants and an app that ties it all together and helps influence employees and their families to better financial health.

Our healthcare system assumes we make decisions based on what is best for us. But it’s not that simple. Everyday stressors often cloud our judgement as to what’s best in the long run. For people with chronic conditions, this can make healthy habit formation difficult. Wellth is a venture-backed digital health company that improves adherence in chronic disease populations. Using the science of behavioral economics—combined with an appreciation for human nature—we uncover and address the unique obstacles that prevent people with chronic conditions from improving patient outcomes. Our program goes beyond current efforts to boost adherence with technology, reminders, and coaching solutions using contingency management and loss aversion to create motivation, behavior change and improve population health at scale. In addition to our RCT-proven outcomes, our easy-to-use mobile platform experience has been proven by health plans, providers, and other organizations to empower members with the incentives and support system they need to establish new healthy habits. Key outcomes for members include improved med and care plan adherence, reduction in readmissions, hospitalizations, and ED utilization, improved PDC, and more. Learn more at www.wellthapp.com.

Lucy Goods operates as a nicotine alternative company. Lucy’s mission is to reduce tobacco-related harm to zero. They provide next-generation nicotine products, with just pure nicotine and food-grade ingredients. The company provides a cleaner convenient alternative to the products on the market.

CloudCath is offering a sensor enabled digital platform for peritoneal dialysis patients that provides early complication detection and safely reduces the number of monthly patient visits.

Physical therapy is powerful—for developing strength, managing emerging conditions, or recovering from surgery. But it’s challenging for physical therapy to make a significant clinical impact because therapists and patients are worn out. Traditional physical therapy leaves more than 50% of therapists suffering from work-related pain and 70% of patients failing to complete their course of care. On both sides of the therapy table, people need better support. At Luna, they’re designing a practice that gives therapists and patients the independence, control, and motivation they need to feel meaningful relief.

Uniform Teeth is an orthodontics practice committed to making orthodontic care as intuitive, accessible, and high quality as possible. Uniform Teeth specializes in providing clear straighteners.

Meissa Vaccines is a start-up pharmaceutical development company focused on the in-licensing and advancement of vaccines for respiratory syncytial virus (RSV, the largest unmet respiratory medical need in pediatrics) and rhinovirus (leading cause of infectious disease worldwide). Their passion is child health, but our vaccine programs have the potential to benefit multiple age groups directly and indirectly. Successful vaccines for respiratory syncytial virus and rhinovirus would have widespread benefits for society and families. These include reducing the burden of acute lower respiratory tract disease, reducing colds, reducing acute asthma exacerbations caused by these viruses, and alleviating missed school and work.

Buoy provides a personalized all-in-one platform to help guide consumers back to health. Whether it's chatting about symptoms with Buoy Assistant to get help in the moment of sickness or researching benefits through Buoy Dashboard, Buoy is available 24/7 to help make self-diagnosis and navigating the healthcare system simple and easy. For employers, Buoy can be custom configured to surface benefits information and wellness programs, guide employees to in-network providers, and fully integrate with other health portals. The company was founded in 2014 and is headquartered in Boston, Massachusetts.

Osmosis is a personalized learning platform that helps you retain more, gain a deeper understanding of concepts & feel more prepared for your courses & exams. Osmosis empowers the clinicians and caregivers with the best learning experience.

Mightier is a gaming platform and family program scientifically-proven to help kids regulate their emotions. It is a bioresponsive program that harnesses the mind-body connection to build emotional regulation in its players. Its program of bioresponsive video games, developed at Boston Children's Hospital and Harvard Medical School, aims to help children with behavioral and emotional challenges learn how to harness emotions in daily life. Mightier was founded in 2016 and is headquartered in Boston, Massachusetts.

SafeRide Health is a healthcare technology platform developer that aims to simplify medical transportation, expedite care coordination, and improve patient outcomes. The company's platform enables health plans to manage its members with greater intelligence and control, delivering end-to-end data transparency while improving patient experience, population health, and programs, and giving patented fleet management solutions to the healthcare industry.

SPARK Neuro is a leading neuroscience company that quantifies brain data for better clinical care and therapeutic discovery. In partnership with the most prestigious institutions in the world, SPARK Neuro enables a new era of analyzing brain activity to better understand neurological and psychiatric conditions. SPARK Neuro combines patented neural metrics with advanced machine learning algorithms in the SPARK Scan, a 10-minute EEG-based evaluation that identifies the first signs of changes in the brain, advancing therapeutic discovery and clinical care.

Opentrons is a developer of pipetting robot technology designed to automate experiments. Their technology is automated laboratory equipment that automates experiments by using the Python language, enabling scientific researchers to make the process faster and less tiresome.

Sonavex is committed to improving outcomes for surgical patients by using cutting-edge imaging technology to provide clinicians with visualization of critical data -- directly at the point of care. The company's technology offers a proprietary technology platform that utilizes ultrasound to detect blood clots after surgery, enabling clinicians to measure critical intravascular flow metrics to detect post-operative clots directly at the point of care and improve outcomes.

There is a growing need for pediatric home care which is currently not being met. Many children are spending time in hospitals and institutional care unnecessarily while home care is 10 times less expensive, more effective, and convenient. The pediatric home care market has not kept pace with this growing demand and is in need of thousands more nurses. To address the growing demand for pediatric home care, Swift Shift is reimagining pediatric home care delivery by creating the first nurse-managed pediatric home care service. Our long term mission is to increase the number of pediatric nurses who choose to work in this field so that every child can access reliable home care. Our unique offering creates more meaningful relationships between patients, families, and nurses. We’ve replaced office-based case managers with nurse care teams and empower them to manage the safe transition from the hospital to long-term home-based care. These self-managed teams choose their patients and control their schedules, creating a greater sense of ownership over their care management. We use an AI-based home care management platform to help our care teams focus on delivering care. No more manuals, no more paper! By providing all the relevant data in an easy-to-access interface, nurses can make better decisions for the well-being of their patients. Most importantly, at Swift Shift we know the best patient outcomes start and end with the best nursing experience. That’s why we are committed to our nurses’ professional development by providing 24/7 training and support services.

EpiBone is a pioneering regenerative medicine company at the forefront of bone and cartilage repair. Leveraging the power of stem cells, biomimicry, and 3D fabrication, they are developing a pipeline of innovative products with enormous potential to revolutionize orthopedic repair. Their lead product, a living, anatomically precise 3D bone graft, completed its Phase I/IIa clinical trial in August 2023. The rest of their pipeline focuses on cartilage repair, and includes an allogeneic osteochondral plug, whose IND was approved in July 2023. Their cartilage portfolio also includes an injectable cartilage filler that was partly funded by the Department of Defense.

MHB Labs is a virtual biotech founded by two leading physician-scientists at Men's Health Boston. Our goal is to leverage clinical insight and industry partnerships to develop new, high-impact products within our field. We have assembled a global team of world-class advisors, contractors, and strategic partners that will allow us to build value around early phase clinical ideas and position them for market success.

Catena Biosciences is a biotechnology company that offers protein conjugation, building biologic structures, and medical research.