MedTech Innovator

INOPASE is a medical device company focused on the development of wirelessly powered, closed-loop implantable neuromodulation technologies. The company is currently working on closed-loop sacral neuromodulation systems for the treatment of overactive bladder and closed-loop brain neuromodulation systems aimed at addressing epilepsy. INOPASE's platform utilizes advanced algorithms to enable personalized treatment plans, detecting symptoms and providing targeted stimulation therapy to patients with chronic neurological diseases.

Ortho-tag is a developer of innovative in-vivo platforms that facilitate the connection between digital health applications and implanted biosensors within the human body. The company's technologies focus on enhancing wireless communication with medical devices through proprietary transcutaneous volume conduction. This enables real-time data exchange, in-vivo storage, and the integration of nanodiagnostic and therapeutic functions in smart medical implants. By providing a comprehensive system for wireless communication and data management, Ortho-tag supports medical device developers in advancing the capabilities of healthcare technology.

NanoBioFAB is a company based in Frederick, Maryland, specializing in the development of wearable, smart healthcare and medical devices utilizing nanotechnology. Founded in 2015, the company produces innovative products such as iNose, a device that allows individuals to detect, track, and monitor their body’s skin vapor-print. This device connects wirelessly to mobile phones, enabling users to track their fat burning rate, assess the effectiveness of their exercise routines, and observe the long-term effects of their dietary choices on metabolic rates. Additionally, NanoBioFAB offers nanoprinting technology and artificial intelligence sensors aimed at enhancing telemedicine and personalized healthcare solutions. The company is dedicated to making advanced healthcare accessible and affordable for both people and pets.

NXgenPort Inc is focused on enhancing cancer care through its innovative digital health technology, which includes an implanted Smart Port for remote patient monitoring between chemotherapy sessions. This technology allows for real-time measurement of cell counts and heart function, enabling early detection of infections and potentially reducing hospitalizations. By gathering critical physiological data, NXgenPort aims to improve patient outcomes while also providing valuable insights for cancer researchers and drug delivery stakeholders. Their system facilitates the remote monitoring of patients' biological responses to treatments, thereby supporting healthcare teams in effectively managing cancer care.

Healthcare is moving to the outpatient setting to save costs, but at home patients struggle with medication adherence and they are readmitted at alarming rates. Hospitals send 1.4 million patients home for 4-6 weeks to administer their own IV antibiotics every year. Twenty percent of patients on outpatient parenteral antimicrobial therapy (OPAT) are readmitted, each costing $80,000 on average. This is a $22.4 billion problem. Clinicians at the 12,200 home infusion providers in the US have no objective way to identify non-adherence to intervene and prevent readmissions. Rather, they call patients to detect non-adherence, which is time-consuming, inaccurate, and prone to reporting bias. They need a better tool than a phone to monitor adherence. The solution is HIVE’s patent pending CloudConnect smart catheter. CloudConnect is a reinvented IV line with a simple embedded mechanoelectrical sensor that detects when a medication source is connected. CloudConnect wirelessly sends this information to electronic medical records. HIVE’s value proposition is that clinicians can detect non-adherence in real time and make treatment decisions and prevent costly readmissions based on objective data. HIVE offers CloudConnect as an alternative to the need for clinicians to call every patient with standard IV lines.

CARI Health is a digital health company based in San Diego, California, that specializes in developing remote medication monitors. Founded in 2015 and incorporated in 2021, CARI Health's innovative monitors utilize wireless sensors worn on the patient's skin to continuously transmit real-time data about medication levels to the cloud. This technology enables clinicians to safely prescribe, dose, and monitor adherence to life-saving medications, thereby enhancing patient care and treatment outcomes.

Lazurite is a pre-revenue medical device startup focused on developing advanced technologies for minimally invasive surgery. The company has raised approximately $18 million from institutional investors, high-net-worth individuals, and over 50 physician champions. Lazurite's product pipeline includes the ArthroFree™ wireless camera system, which is the first fully wireless minimally invasive camera system designed for operating rooms, and ORFree™, a mobile minimally invasive surgical camera platform. Both products utilize the company’s innovative Meridiem™ light engine technology. By providing modular wireless solutions, Lazurite aims to enhance surgical safety and efficiency, offering alternatives to traditional wired systems and outdated technologies.

PyrAmes is a healthcare technology company that has created an innovative, paper-thin, flexible device for non-invasive blood pressure monitoring. This ultra low-power device is designed to deliver continuous and accurate blood pressure measurements wirelessly, making it suitable for patients of all ages, from newborns to seniors. PyrAmes aims to transform healthcare delivery by providing a platform that enables healthcare providers to conduct pain-free blood pressure monitoring, particularly benefiting vulnerable populations such as neonates.

Synotrac is a technology company focused on developing innovative sensor technology aimed at detecting infections in vivo. Its patent-pending device is designed to monitor infection at the source, particularly after joint surgery. By analyzing the body's immune response, the device provides real-time alerts to both patients and their physicians, facilitating early detection of infections that may arise during the healing process. The information collected is relayed to a smartphone for quick analysis and reporting, allowing patients to avoid unnecessary hospital visits or additional surgeries. Synotrac's approach offers a significant advancement in post-surgical care, enhancing patient outcomes through timely intervention.

Nanowear, Inc. is a technology company specializing in textile-based nanosensor solutions for wireless and real-time electrophysiological monitoring. Founded in 2014 and headquartered in Brooklyn, New York, with a research and development facility in University Park, Pennsylvania, Nanowear develops innovative products such as SimplECG, a remote cardiac monitoring undergarment, and SimpleSense, designed for the management of congestive heart failure. These garments collect multi-channel electrocardiogram (ECG), heart rate, and respiratory rate data, transmitting it to a web-based portal accessible by healthcare professionals via a mobile application. The company's proprietary technology serves various markets, including cardiac, neurological, industrial safety, government, sports medicine, and performance diagnostics, providing accurate, continuous, and cost-effective diagnostic data in an unobtrusive manner.

V-Sense Medical is a developer of innovative remote medical monitoring devices designed to enhance patient care in critical medical settings. Utilizing advanced radar technology originally developed by NASA, the company offers a contactless solution for monitoring vital signs, including heart rate and respiratory rate. This approach eliminates the need for traditional monitoring equipment such as wearables, leads, contacts, stickers, or wires, addressing key challenges in medical environments, such as patient safety, comfort, and measurement accuracy. By providing continuous health insights without the burdens of conventional monitoring systems, V-Sense Medical enables healthcare professionals to respond swiftly to patient needs, ultimately improving the efficiency of diagnostic and resuscitative efforts in hospitals and clinics.

TinyKicks is a technology company headquartered in Irvine, California, founded in 2014 by France Helfer. The company specializes in developing a wireless smart sensor system that captures fetal movement using machine learning to promote healthy pregnancy outcomes. Its flagship product, the TinyKicks eMotion fetal activity monitor, is a wearable device that detects the user's baby kicks, distinguishing them from the mother's movements. This continuous monitoring provides real-time data, which is automatically uploaded to the user's smartphone. The system utilizes machine learning algorithms to identify abnormal fetal movement, enabling pregnant women to receive timely notifications about potential complications, thereby reducing costs associated with pregnancy-related issues and enhancing overall pregnancy health tracking.