MiNDERA Corporation
Convertible Note in 2024
MiNDERA Corporation specializes in the development of non-invasive molecular testing devices aimed at diagnosing skin cancer and other skin diseases. The company has created a micro-needle array patch that allows for pain-free and minimally invasive extraction of biomarkers, such as RNA, DNA, and proteins, from the skin without the need for traditional biopsies. Additionally, MiNDERA develops specialized patches for whole transcriptome extraction and skin microbiome extraction, which are designed for research applications. Founded in 2013, MiNDERA is headquartered in Palo Alto, California.
PinkDx is a biotechnology company specializing in women's health. It develops molecular tests to improve diagnostic outcomes for women with vague gynecological cancer symptoms, offering alternatives to invasive procedures. This enables more comfortable and efficient resolution of health concerns, providing timely and positive impacts on patients' lives.
Circular Genomics
Series A in 2024
Circular Genomics, established in 2021 with headquarters in Albuquerque, New Mexico, specializes in pioneering precision medicine using circular RNA as novel biomarkers. The company focuses on improving the diagnosis and treatment of neurological and psychiatric conditions by developing RNA-based diagnostic assays, notably for depressive disorders. Their innovative approach enables evidence-based treatments, reducing time to therapeutic response and enhancing physicians' ability to manage psychiatric and neurological diseases effectively.
Airvet Inc. is a veterinary telemedicine platform that connects pet owners with veterinarians through its mobile application. Founded in 2018 and headquartered in Beverly Hills, California, Airvet enables users to schedule virtual appointments, facilitating real-time interactions via video, audio, and chat. The platform aims to enhance the continuity of care between pet parents and their veterinarians, thereby strengthening existing relationships. Airvet's services include general health checkups, addressing medical and behavioral questions, and conducting follow-up consultations, all designed to provide affordable access to veterinary care. By modernizing the pet care experience, Airvet helps ensure that pets receive the necessary support to lead happy and healthy lives.
Vytelle, LLC is a biotechnology company focused on enhancing cattle genetics through advanced reproductive technology. Founded in 2015 and based in Hermiston, Oregon, Vytelle offers ovum pick-up and embryo production services specifically tailored for beef and dairy cows. The company employs a proprietary culture system for embryo development that does not utilize fetal calf serum, enabling the production of freezable embryos. This innovative approach allows commercial cattle producers to achieve sustainable genetic advancements over multiple generations. Vytelle collaborates with industry specialists and licensed veterinarians to optimize herd management and reproductive outcomes, positioning itself as a leader in precision livestock solutions.
Silicon Ranch
Private Equity Round in 2023
Silicon Ranch Corporation is a Nashville-based company that develops, owns, and operates utility-scale solar power projects across the United States. Founded in 2010, it specializes in delivering cost-effective and innovative solar energy solutions for a diverse range of clients, including utilities, military facilities, and commercial businesses. The company is committed to long-term ownership of its projects, which reinforces its dedication to partners and the communities it serves. In addition to its solar energy initiatives, Silicon Ranch operates a regional energy-training center that provides education and training in solar installation, maintenance, and weatherization. Through its efforts, the company aims to promote economic development and create job opportunities while contributing to the transition to sustainable energy sources.
AngelEye Health
Series B in 2022
AngelEye Health is a developer of a tele-engagement platform designed to integrate parents into the care team during their child's stay in neonatal intensive care units (NICUs) and pediatric units. The company offers a comprehensive, HIPAA-compliant solution that includes bedside cameras, patient communication tools, feeding management systems, and targeted educational resources. These services enhance care team workflows and provide families with improved access to their child's treatment plans and progress through any connected device. By fostering meaningful care experiences, AngelEye Health aims to improve family satisfaction, enhance care delivery efficiency, and ultimately elevate the quality of care for patients.
Verility is a company focused on enhancing fertility in livestock to meet the growing demand for meat protein and improve food sustainability. It develops veterinary medical devices that provide animal-side sperm quality assessments and ovulation detection. By utilizing advanced image recognition and artificial intelligence, Verility enables rapid analysis of semen samples and cell morphology at the point-of-care. This technology helps livestock producers and breeders accurately determine when animals are ready for breeding, ultimately accelerating reproductive performance and supporting efficient meat production.
Targan is a bio-systems company dedicated to advancing animal health and productivity across the poultry, livestock, and aquaculture sectors. The company has developed an innovative vaccination system that enhances the delivery of vaccines to newly hatched chicks with precision, moving away from traditional mass spray methods. This technology ensures that each chick receives the appropriate vaccination, significantly improving immunization levels and promoting a robust natural immune response. By prioritizing accuracy and consistency in the vaccination process, Targan aims to enhance overall flock health, reduce reliance on antibiotics, and contribute to more efficient animal production, ultimately benefiting producers both on the farm and in processing plants.
Silicon Ranch
Private Equity Round in 2022
Silicon Ranch Corporation is a Nashville-based company that develops, owns, and operates utility-scale solar power projects across the United States. Founded in 2010, it specializes in delivering cost-effective and innovative solar energy solutions for a diverse range of clients, including utilities, military facilities, and commercial businesses. The company is committed to long-term ownership of its projects, which reinforces its dedication to partners and the communities it serves. In addition to its solar energy initiatives, Silicon Ranch operates a regional energy-training center that provides education and training in solar installation, maintenance, and weatherization. Through its efforts, the company aims to promote economic development and create job opportunities while contributing to the transition to sustainable energy sources.
Circular Genomics
Seed Round in 2021
Circular Genomics, established in 2021 with headquarters in Albuquerque, New Mexico, specializes in pioneering precision medicine using circular RNA as novel biomarkers. The company focuses on improving the diagnosis and treatment of neurological and psychiatric conditions by developing RNA-based diagnostic assays, notably for depressive disorders. Their innovative approach enables evidence-based treatments, reducing time to therapeutic response and enhancing physicians' ability to manage psychiatric and neurological diseases effectively.
Targan is a bio-systems company dedicated to advancing animal health and productivity across the poultry, livestock, and aquaculture sectors. The company has developed an innovative vaccination system that enhances the delivery of vaccines to newly hatched chicks with precision, moving away from traditional mass spray methods. This technology ensures that each chick receives the appropriate vaccination, significantly improving immunization levels and promoting a robust natural immune response. By prioritizing accuracy and consistency in the vaccination process, Targan aims to enhance overall flock health, reduce reliance on antibiotics, and contribute to more efficient animal production, ultimately benefiting producers both on the farm and in processing plants.
MiNDERA Corporation
Series A in 2021
MiNDERA Corporation specializes in the development of non-invasive molecular testing devices aimed at diagnosing skin cancer and other skin diseases. The company has created a micro-needle array patch that allows for pain-free and minimally invasive extraction of biomarkers, such as RNA, DNA, and proteins, from the skin without the need for traditional biopsies. Additionally, MiNDERA develops specialized patches for whole transcriptome extraction and skin microbiome extraction, which are designed for research applications. Founded in 2013, MiNDERA is headquartered in Palo Alto, California.
Advanced Animal Diagnostics
Venture Round in 2021
Advanced Animal Diagnostics, Inc. specializes in the research, development, and commercialization of on-farm diagnostic tools aimed at the early detection of subclinical mastitis in dairy cows. Founded in 2001 and based in Durham, North Carolina, the company offers innovative products such as the QScout Farm Lab, an analyzer system that detects infections before visible symptoms occur, and the QScout Milk Leukocyte Differential rapid test, which identifies and differentiates leukocytes in milk to facilitate early mastitis detection. Additionally, Advanced Animal Diagnostics provides the QuickSmear slide for animal research and the SCC+ System for timely mastitis diagnosis. The company's solutions focus on enhancing the management of disease states and improving the reproductive, nutritional, and overall health of production animals, serving veterinarians and livestock producers to promote healthier and more productive animal care.
Silicon Ranch
Funding Round in 2020
Silicon Ranch Corporation is a Nashville-based company that develops, owns, and operates utility-scale solar power projects across the United States. Founded in 2010, it specializes in delivering cost-effective and innovative solar energy solutions for a diverse range of clients, including utilities, military facilities, and commercial businesses. The company is committed to long-term ownership of its projects, which reinforces its dedication to partners and the communities it serves. In addition to its solar energy initiatives, Silicon Ranch operates a regional energy-training center that provides education and training in solar installation, maintenance, and weatherization. Through its efforts, the company aims to promote economic development and create job opportunities while contributing to the transition to sustainable energy sources.
AN2 Therapeutics
Series A in 2019
AN2 Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Menlo Park, California, focused on the research, development, and commercialization of innovative medicines for infectious diseases. Founded in 2017, the company aims to address significant unmet medical needs through its development of novel therapeutics. Its lead product candidate, epetraborole, is a once-daily oral treatment designed for patients suffering from chronic non-tuberculous mycobacterial lung disease. AN2 Therapeutics is committed to leveraging advanced biomedical expertise to create transformative solutions for patients dealing with serious and rare infectious diseases. The company has also established a strategic partnership with Brii Biosciences to enhance its development efforts.
Targan is a bio-systems company dedicated to advancing animal health and productivity across the poultry, livestock, and aquaculture sectors. The company has developed an innovative vaccination system that enhances the delivery of vaccines to newly hatched chicks with precision, moving away from traditional mass spray methods. This technology ensures that each chick receives the appropriate vaccination, significantly improving immunization levels and promoting a robust natural immune response. By prioritizing accuracy and consistency in the vaccination process, Targan aims to enhance overall flock health, reduce reliance on antibiotics, and contribute to more efficient animal production, ultimately benefiting producers both on the farm and in processing plants.
PhaseBio Pharmaceuticals, Inc., established in 2002 and based in Malvern, Pennsylvania, is a clinical-stage biopharmaceutical company dedicated to developing novel therapies for cardiopulmonary diseases. Its primary focus is on PB2452, a reversal agent for the antiplatelet drug ticagrelor, currently in Phase III trials for managing uncontrolled bleeding events or urgent surgeries. Additionally, PhaseBio is developing PB1046, a fusion protein in Phase IIb trials for treating pulmonary arterial hypertension, and PB6440, an oral agent for resistant hypertension. The company's proprietary technology, elastin-like polypeptides (ELPs), enhances the stability, bioavailability, and efficacy of proteins and peptides, aiming to improve patient outcomes and reduce side effects.
ORIG3N, Inc. is a biotechnology company focused on developing innovative treatments for rare genetically inherited diseases, particularly targeting conditions related to the heart, liver, and neurodegeneration. Founded in 2014 and based in Boston, Massachusetts, ORIG3N utilizes induced pluripotent stem cell technology that allows for the differentiation of cells into any type found in the body. This technology is employed to test drug efficacy, screen for medication toxicity, and create personalized treatment pathways. The company offers a range of products, including LifeProfiles, which provides genetic insights related to fitness, metabolism, and exercise recovery; the Run DNA test for optimizing running performance; AURA, which assesses skin health; and Life Capsule, a repository for blood cells aimed at regenerative medicine development.
NeuroTronik
Series B in 2017
NeuroTronik, spun out of medical technology incubator Synecor, is developing a medical device that could take the place of drugs currently used to heart failure. Read more about the company's technology,
Boragen Inc. is a biotechnology company based in Durham, North Carolina, founded in 2015. It specializes in the design and development of multifunctional small molecule boron solutions for applications in crop protection, animal health, and human health. Boragen's innovative synthetic chemistry platform enables the production of next-generation fungicides, including BAG8, a multisite fungicide, and BN2266, which targets mRNA processing. The company is also developing a dual function nematicide-fungicide for root protection and endo-parasiticides that can overcome resistance. By leveraging the unique properties of boron, Boragen aims to create sustainable agricultural solutions that reduce the probability of fungicide resistance and minimize chemical usage while maintaining efficacy across various sectors.
G1 Therapeutics
Series C in 2016
G1 Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Research Triangle Park, North Carolina, focused on the discovery, development, and commercialization of small molecule therapeutics for cancer treatment. The company is advancing several key drug candidates, including trilaciclib, an intravenous cyclin-dependent kinases (CDK) 4/6 inhibitor currently in Phase 1b/2 clinical trials for extensive-stage small cell lung cancer and Phase 2 trials for first-line small cell lung cancer and metastatic triple-negative breast cancer. Additionally, G1 is developing lerociclib, an oral CDK4/6 inhibitor in Phase 1b/2a trials for breast cancer and Phase 1b trials for non-small cell lung cancer, as well as rintodestrant, an oral selective estrogen receptor degrader in Phase I/2 trials. The company collaborates with Quantum Leap Healthcare Collaborative to explore trilaciclib's potential in neoadjuvant treatment for locally advanced breast cancer. Founded in 2008, G1 Therapeutics aims to address unmet medical needs in oncology by enhancing the effectiveness of existing cancer therapies.
ORIG3N, Inc. is a biotechnology company focused on developing innovative treatments for rare genetically inherited diseases, particularly targeting conditions related to the heart, liver, and neurodegeneration. Founded in 2014 and based in Boston, Massachusetts, ORIG3N utilizes induced pluripotent stem cell technology that allows for the differentiation of cells into any type found in the body. This technology is employed to test drug efficacy, screen for medication toxicity, and create personalized treatment pathways. The company offers a range of products, including LifeProfiles, which provides genetic insights related to fitness, metabolism, and exercise recovery; the Run DNA test for optimizing running performance; AURA, which assesses skin health; and Life Capsule, a repository for blood cells aimed at regenerative medicine development.
splitsecnd
Venture Round in 2015
splitsecnd is a developer of a unique portable plug-in vehicle connectivity device that enhances driver safety by providing automatic crash response and roadside assistance. Designed to be easily installed in any vehicle through the 12V lighter outlet, the device utilizes airbag sensor technology to detect accidents and immediately alert emergency personnel. In addition to its automatic features, splitsecnd allows for manual activation during emergencies. The device also offers GPS capabilities and comprehensive trip analytics, enabling users to track routes, promote safe driving behaviors, and locate parked vehicles. This versatile solution is particularly beneficial for seniors, teens, and drivers of all ages, ensuring support on the road regardless of the circumstances or vehicle type, all without the need for a cell phone.
Restore Medical Solutions
Series A in 2015
Restore Medical Solutions, Inc., established in 2012 and based in Memphis, Tennessee, specializes in manufacturing modular sterilization tray systems for hospitals and surgery centers. Their products aim to reduce surgical site infections (SSIs), enhance safety, and improve productivity within the healthcare industry by minimizing the risk of contamination from medical instruments.
MedCenterDisplay
Series B in 2015
MedCenterDisplay, LLC specializes in digital patient engagement solutions for hospitals and clinics throughout the United States. Based in Brentwood, Tennessee, the company offers a comprehensive range of services, including digital signage, online marketing, social media management, and application development. These solutions are designed to enhance patient satisfaction, reduce avoidable readmissions, and improve healthcare-related metrics such as HCAHPS scores. MedCenterDisplay's digital signage systems effectively communicate with patients and their families in healthcare facilities, providing engaging content while they wait for services. The company's offerings also encompass search engine optimization, reputation management, and video production, all aimed at empowering healthcare organizations to connect with their patients more effectively. Originally incorporated as AMS, LLC in 2007, MedCenterDisplay operates as a subsidiary of PatientPoint, LLC as of November 2016.
NuSirt Sciences, Inc. is a biotechnology company based in Nashville, Tennessee, that focuses on developing innovative products for metabolic diseases linked to over-nutrition, such as obesity and diabetes. Established in 2007, the company has created a technology platform that combines natural compounds with pharmaceutical agents to activate sirtuin pathways, aiming to prevent and treat chronic conditions associated with aging. Its flagship product, NS-0100, combines the natural compound leucine with a low dose of metformin to address type 2 diabetes, particularly for patients who experience gastrointestinal side effects from standard metformin treatment. NuSirt is currently conducting Phase 2 clinical trials to determine the optimal dosage of NS-0100. The company has filed eleven patent applications related to its technologies, with two patents already issued, and has successfully completed four clinical studies alongside various pre-clinical investigations.
Myomo, a wearable medical robotics company based in Cambridge, Massachusetts, specializes in designing and producing myoelectric orthotics for individuals with neuromuscular disorders. Founded in 2004, Myomo offers products such as the MyoPro and mPower 1000, which are upper limb brace orthoses designed to support weak or paralyzed arms, enhancing functional activities of daily living. These devices help restore mobility in patients with conditions like brachial plexus injury, stroke, traumatic brain injury, spinal cord injury, multiple sclerosis, cerebral palsy, muscular dystrophy, and other neurological disorders. Myomo's products are sold to orthotics and prosthetics providers, the Veterans Health Administration, rehabilitation hospitals, and distributors. The company also provides complementary technologies such as PERL technique for functional repetitive task practice, myGames for virtual reality-based therapeutic training, and myProgress for tracking progress using their devices.
Contego Medical
Series B in 2015
Contego Medical, Inc. is a medical device company specializing in the development of embolic protection devices aimed at enhancing safety and efficacy during cardiovascular and endovascular procedures. Founded in 2005 and headquartered in Raleigh, North Carolina, with an additional office in Curitiba, Brazil, the company offers a range of integrated products, including angioplasty balloons and stent delivery catheters designed for interventions in carotid artery disease, peripheral artery disease, and deep vein thrombosis. Notably, Contego Medical has received FDA clearance for several innovative devices, such as the Paladin Carotid PTA Balloon System, the Vanguard IEP Peripheral Balloon Angioplasty System, and the Excipio SV Thrombectomy Device. Its technology integrates embolic protection directly onto the treatment catheter, streamlining procedures and improving patient outcomes.
G1 Therapeutics
Series B in 2015
G1 Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Research Triangle Park, North Carolina, focused on the discovery, development, and commercialization of small molecule therapeutics for cancer treatment. The company is advancing several key drug candidates, including trilaciclib, an intravenous cyclin-dependent kinases (CDK) 4/6 inhibitor currently in Phase 1b/2 clinical trials for extensive-stage small cell lung cancer and Phase 2 trials for first-line small cell lung cancer and metastatic triple-negative breast cancer. Additionally, G1 is developing lerociclib, an oral CDK4/6 inhibitor in Phase 1b/2a trials for breast cancer and Phase 1b trials for non-small cell lung cancer, as well as rintodestrant, an oral selective estrogen receptor degrader in Phase I/2 trials. The company collaborates with Quantum Leap Healthcare Collaborative to explore trilaciclib's potential in neoadjuvant treatment for locally advanced breast cancer. Founded in 2008, G1 Therapeutics aims to address unmet medical needs in oncology by enhancing the effectiveness of existing cancer therapies.
ORIG3N
Venture Round in 2015
ORIG3N, Inc. is a biotechnology company focused on developing innovative treatments for rare genetically inherited diseases, particularly targeting conditions related to the heart, liver, and neurodegeneration. Founded in 2014 and based in Boston, Massachusetts, ORIG3N utilizes induced pluripotent stem cell technology that allows for the differentiation of cells into any type found in the body. This technology is employed to test drug efficacy, screen for medication toxicity, and create personalized treatment pathways. The company offers a range of products, including LifeProfiles, which provides genetic insights related to fitness, metabolism, and exercise recovery; the Run DNA test for optimizing running performance; AURA, which assesses skin health; and Life Capsule, a repository for blood cells aimed at regenerative medicine development.
Lineagen, Inc. is a genetic diagnostic company specializing in genetic testing and clinical information services for neurodevelopmental disorders, particularly autism. Founded in 2002 and based in Salt Lake City, Utah, Lineagen offers a range of services including FirstStepDx PLUS, a chromosomal microarray platform designed to identify genomic changes related to autism and other neurodevelopmental conditions, and NextStepDx PLUS, a genetic sequencing test that detects subtle genomic variations. The company also provides M-CHAT.org, an online tool for developmental assessment by healthcare professionals and parents. Lineagen's commitment to improving health outcomes for individuals affected by autism and similar disorders is supported by its access to the Utah Population Database, a resource that enhances its research capabilities in identifying genetic causes and diagnostic pathways for complex diseases. As of August 2020, Lineagen operates as a subsidiary of Bionano Genomics, Inc.
Clearside Biomedical
Series B in 2014
Clearside Biomedical, Inc. is a biopharmaceutical company focused on developing treatments for serious eye diseases with the aim of restoring and preserving vision. Founded in 2011 and headquartered in Alpharetta, Georgia, the company specializes in a proprietary ocular microinjection platform that allows for targeted delivery of therapeutic products to specific compartments of the eye. This innovative approach includes the use of the SCS Microinjector for administering therapies directly into the suprachoroidal space, enabling a non-surgical, repeatable procedure. Among its product pipeline, Clearside is developing XIPERE, a triamcinolone acetonide injectable suspension for macular edema, and CLS-AX, an axitinib for suprachoroidal injection. The company is dedicated to advancing pharmacological therapies for sight-threatening conditions by ensuring precise and effective treatment delivery.
MedCenterDisplay
Venture Round in 2014
MedCenterDisplay, LLC specializes in digital patient engagement solutions for hospitals and clinics throughout the United States. Based in Brentwood, Tennessee, the company offers a comprehensive range of services, including digital signage, online marketing, social media management, and application development. These solutions are designed to enhance patient satisfaction, reduce avoidable readmissions, and improve healthcare-related metrics such as HCAHPS scores. MedCenterDisplay's digital signage systems effectively communicate with patients and their families in healthcare facilities, providing engaging content while they wait for services. The company's offerings also encompass search engine optimization, reputation management, and video production, all aimed at empowering healthcare organizations to connect with their patients more effectively. Originally incorporated as AMS, LLC in 2007, MedCenterDisplay operates as a subsidiary of PatientPoint, LLC as of November 2016.
Castle Biosciences
Venture Round in 2014
Castle Biosciences, Inc. is a commercial-stage biotechnology company headquartered in Friendswood, Texas, specializing in diagnostic and prognostic tests for dermatological cancers. The company develops innovative genomic tests to aid physicians and patients in making informed treatment decisions. Its flagship product, DecisionDx-Melanoma, is a multi-gene expression profile test designed to identify stage I and II melanoma patients at high risk of metastasis. Additionally, Castle Biosciences offers the DecisionDx-UM test, which assesses the risk of metastasis in patients with uveal melanoma, a rare eye cancer. The company is also advancing two proprietary tests aimed at addressing cutaneous squamous cell carcinoma and suspicious pigmented lesions, both of which represent significant clinical needs in dermatological oncology. Through its products, Castle Biosciences aims to provide personalized and actionable genomic information, thereby enhancing cancer diagnosis and management.
InvisionHeart
Series A in 2014
InvisionHeart is a company focused on enhancing cardiac care through innovative technology. It has developed a mobile electrocardiograph system that captures vital cardiac data, allowing a network of healthcare professionals—including physicians, nurses, and technicians—to securely access and annotate patient electrocardiogram tracings. The technology was initially created by a collaborative team of physicians and engineers at Vanderbilt University, addressing practical clinical challenges faced in heart care. With a strong leadership team and a dedicated clinical advisory board, InvisionHeart aims to improve the quality of care for heart patients, ensuring that essential cardiac information is readily available to healthcare providers regardless of their location.
NuSirt Sciences, Inc. is a biotechnology company based in Nashville, Tennessee, that focuses on developing innovative products for metabolic diseases linked to over-nutrition, such as obesity and diabetes. Established in 2007, the company has created a technology platform that combines natural compounds with pharmaceutical agents to activate sirtuin pathways, aiming to prevent and treat chronic conditions associated with aging. Its flagship product, NS-0100, combines the natural compound leucine with a low dose of metformin to address type 2 diabetes, particularly for patients who experience gastrointestinal side effects from standard metformin treatment. NuSirt is currently conducting Phase 2 clinical trials to determine the optimal dosage of NS-0100. The company has filed eleven patent applications related to its technologies, with two patents already issued, and has successfully completed four clinical studies alongside various pre-clinical investigations.
NuSirt Sciences, Inc. is a biotechnology company based in Nashville, Tennessee, that focuses on developing innovative products for metabolic diseases linked to over-nutrition, such as obesity and diabetes. Established in 2007, the company has created a technology platform that combines natural compounds with pharmaceutical agents to activate sirtuin pathways, aiming to prevent and treat chronic conditions associated with aging. Its flagship product, NS-0100, combines the natural compound leucine with a low dose of metformin to address type 2 diabetes, particularly for patients who experience gastrointestinal side effects from standard metformin treatment. NuSirt is currently conducting Phase 2 clinical trials to determine the optimal dosage of NS-0100. The company has filed eleven patent applications related to its technologies, with two patents already issued, and has successfully completed four clinical studies alongside various pre-clinical investigations.
Diagnovus
Seed Round in 2013
Diagnovus, established in 2011 and located in Nashville, TN, is dedicated to advancing patient health through innovative molecular diagnostics. The company focuses on developing diagnostic tests aimed at rare forms of cancer, including pediatric cancers, to enhance the decision-making process for physicians, patients, and their families. By prioritizing evidence-based solutions, Diagnovus aims to improve treatment outcomes and facilitate more effective care. Their commitment to serving the healthcare community reflects a passion for enhancing the quality of life for patients while also promoting a more efficient allocation of healthcare resources.
G1 Therapeutics
Series A in 2013
G1 Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Research Triangle Park, North Carolina, focused on the discovery, development, and commercialization of small molecule therapeutics for cancer treatment. The company is advancing several key drug candidates, including trilaciclib, an intravenous cyclin-dependent kinases (CDK) 4/6 inhibitor currently in Phase 1b/2 clinical trials for extensive-stage small cell lung cancer and Phase 2 trials for first-line small cell lung cancer and metastatic triple-negative breast cancer. Additionally, G1 is developing lerociclib, an oral CDK4/6 inhibitor in Phase 1b/2a trials for breast cancer and Phase 1b trials for non-small cell lung cancer, as well as rintodestrant, an oral selective estrogen receptor degrader in Phase I/2 trials. The company collaborates with Quantum Leap Healthcare Collaborative to explore trilaciclib's potential in neoadjuvant treatment for locally advanced breast cancer. Founded in 2008, G1 Therapeutics aims to address unmet medical needs in oncology by enhancing the effectiveness of existing cancer therapies.
Diagnovus
Seed Round in 2013
Diagnovus, established in 2011 and located in Nashville, TN, is dedicated to advancing patient health through innovative molecular diagnostics. The company focuses on developing diagnostic tests aimed at rare forms of cancer, including pediatric cancers, to enhance the decision-making process for physicians, patients, and their families. By prioritizing evidence-based solutions, Diagnovus aims to improve treatment outcomes and facilitate more effective care. Their commitment to serving the healthcare community reflects a passion for enhancing the quality of life for patients while also promoting a more efficient allocation of healthcare resources.
Best ABT Molecular Imaging
Venture Round in 2013
Best ABT Molecular Imaging, Inc. is a medical imaging company specializing in the design, manufacture, marketing, and servicing of biomarker generator systems and related accessories. The company offers the BG-75 Biomarker Generator, which produces unit doses of molecular imaging drugs for positron emission tomography (PET) at the point of use, ensuring immediate availability and quality through comprehensive control tests for each dose generated. Founded by Ron and Lynda Nutt in 2006, Best ABT leverages its expertise in molecular imaging, which has roots dating back to the early 1980s. The company's innovative technology includes a self-shielded mini-cyclotron for producing the positron-emitting F-18 isotope and a microchemistry system for labeling specific molecules. Headquartered in Louisville, Tennessee, Best ABT distributes its products globally through a network of sales and service distributors, facilitating the expansion of PET imaging capabilities worldwide.
SwingPal
Seed Round in 2013
SwingPal, LLC is a company based in Franklin, Tennessee, that operates an innovative online platform for learning golf. Established in 2010, the platform connects golfers with instructors through web and mobile access. Users can record their swings using a smartphone and upload the videos to their SwingPal accounts. They then receive detailed feedback, including annotated video and audio analysis from golf professionals, along with additional instructional content. This service is designed to help golfers improve their skills and modify their gameplay effectively.
StreamWeaver
Series A in 2013
StreamWeaver is a software company based in Nashville, Tennessee. The company specializes in developing innovative technology solutions aimed at enhancing collaboration and productivity. Its flagship product is a multi-angle mobile video application that facilitates seamless connections between users, allowing them to record videos together and automatically generating split-screen content. Additionally, StreamWeaver offers a technology platform that integrates and streams data from popular IT tools in near real-time, utilizing event-driven automation to enhance operational efficiency. This platform enables organizations to reduce integration costs while achieving greater observability across their IT operations.
Diagnovus
Seed Round in 2013
Diagnovus, established in 2011 and located in Nashville, TN, is dedicated to advancing patient health through innovative molecular diagnostics. The company focuses on developing diagnostic tests aimed at rare forms of cancer, including pediatric cancers, to enhance the decision-making process for physicians, patients, and their families. By prioritizing evidence-based solutions, Diagnovus aims to improve treatment outcomes and facilitate more effective care. Their commitment to serving the healthcare community reflects a passion for enhancing the quality of life for patients while also promoting a more efficient allocation of healthcare resources.
Pathfinder Technologies
Venture Round in 2013
Pathfinder Technologies (formerly Pathfinder Therapeutics, Inc.), a medical device company, engages in the design, development, and manufacture of solutions in the field of navigated abdominal surgery. The company provides an integrated intra-operative image guidance system for open liver surgical procedure; and accessories, including IRED localization probes, navigated RF ablators, and navigated ultrasonic aspirators. Its system consists of a software architecture that allows the surgeon to display a 3D view of the liver. Its system is used in various open liver surgery applications, including hepatic resection, open ablation, open biopsy, living donor transplant, cyst removal, and tumor removal. Pathfinder Technologies was founded in 2004 and is based in Nashville, Tennessee.
Diagnovus
Seed Round in 2013
Diagnovus, established in 2011 and located in Nashville, TN, is dedicated to advancing patient health through innovative molecular diagnostics. The company focuses on developing diagnostic tests aimed at rare forms of cancer, including pediatric cancers, to enhance the decision-making process for physicians, patients, and their families. By prioritizing evidence-based solutions, Diagnovus aims to improve treatment outcomes and facilitate more effective care. Their commitment to serving the healthcare community reflects a passion for enhancing the quality of life for patients while also promoting a more efficient allocation of healthcare resources.
American Hometown Media
Seed Round in 2013
American Hometown Media, Inc. is a digital media company based in Nashville, Tennessee, specializing in the publishing of content that highlights American home cooks. Founded in 2011, the company operates an internet platform that syndicates editorial content to community newspapers, magazines, and other media outlets across the country. It focuses on celebrating the culinary contributions of everyday individuals, positioning them as the central figures in its offerings. One of its key features is Just A Pinch Recipes, a digital recipe and coupon social network aimed at home cooks. Additionally, American Hometown Media provides Just A Pinch Syndicated Media, which delivers content related to recipes and the cultural heritage of America's hometowns. By leveraging traditional publishing roots while embracing digital technology, the company effectively connects with a broad audience, reaching around two million households weekly through its syndicated columns.
Pathfinder Technologies
Seed Round in 2013
Pathfinder Technologies (formerly Pathfinder Therapeutics, Inc.), a medical device company, engages in the design, development, and manufacture of solutions in the field of navigated abdominal surgery. The company provides an integrated intra-operative image guidance system for open liver surgical procedure; and accessories, including IRED localization probes, navigated RF ablators, and navigated ultrasonic aspirators. Its system consists of a software architecture that allows the surgeon to display a 3D view of the liver. Its system is used in various open liver surgery applications, including hepatic resection, open ablation, open biopsy, living donor transplant, cyst removal, and tumor removal. Pathfinder Technologies was founded in 2004 and is based in Nashville, Tennessee.
SwingPal
Seed Round in 2013
SwingPal, LLC is a company based in Franklin, Tennessee, that operates an innovative online platform for learning golf. Established in 2010, the platform connects golfers with instructors through web and mobile access. Users can record their swings using a smartphone and upload the videos to their SwingPal accounts. They then receive detailed feedback, including annotated video and audio analysis from golf professionals, along with additional instructional content. This service is designed to help golfers improve their skills and modify their gameplay effectively.
StreamWeaver
Series A in 2013
StreamWeaver is a software company based in Nashville, Tennessee. The company specializes in developing innovative technology solutions aimed at enhancing collaboration and productivity. Its flagship product is a multi-angle mobile video application that facilitates seamless connections between users, allowing them to record videos together and automatically generating split-screen content. Additionally, StreamWeaver offers a technology platform that integrates and streams data from popular IT tools in near real-time, utilizing event-driven automation to enhance operational efficiency. This platform enables organizations to reduce integration costs while achieving greater observability across their IT operations.
Best ABT Molecular Imaging
Series C in 2012
Best ABT Molecular Imaging, Inc. is a medical imaging company specializing in the design, manufacture, marketing, and servicing of biomarker generator systems and related accessories. The company offers the BG-75 Biomarker Generator, which produces unit doses of molecular imaging drugs for positron emission tomography (PET) at the point of use, ensuring immediate availability and quality through comprehensive control tests for each dose generated. Founded by Ron and Lynda Nutt in 2006, Best ABT leverages its expertise in molecular imaging, which has roots dating back to the early 1980s. The company's innovative technology includes a self-shielded mini-cyclotron for producing the positron-emitting F-18 isotope and a microchemistry system for labeling specific molecules. Headquartered in Louisville, Tennessee, Best ABT distributes its products globally through a network of sales and service distributors, facilitating the expansion of PET imaging capabilities worldwide.
StreamWeaver
Seed Round in 2012
StreamWeaver is a software company based in Nashville, Tennessee. The company specializes in developing innovative technology solutions aimed at enhancing collaboration and productivity. Its flagship product is a multi-angle mobile video application that facilitates seamless connections between users, allowing them to record videos together and automatically generating split-screen content. Additionally, StreamWeaver offers a technology platform that integrates and streams data from popular IT tools in near real-time, utilizing event-driven automation to enhance operational efficiency. This platform enables organizations to reduce integration costs while achieving greater observability across their IT operations.
Diagnovus
Seed Round in 2012
Diagnovus, established in 2011 and located in Nashville, TN, is dedicated to advancing patient health through innovative molecular diagnostics. The company focuses on developing diagnostic tests aimed at rare forms of cancer, including pediatric cancers, to enhance the decision-making process for physicians, patients, and their families. By prioritizing evidence-based solutions, Diagnovus aims to improve treatment outcomes and facilitate more effective care. Their commitment to serving the healthcare community reflects a passion for enhancing the quality of life for patients while also promoting a more efficient allocation of healthcare resources.
Pathfinder Technologies
Venture Round in 2012
Pathfinder Technologies (formerly Pathfinder Therapeutics, Inc.), a medical device company, engages in the design, development, and manufacture of solutions in the field of navigated abdominal surgery. The company provides an integrated intra-operative image guidance system for open liver surgical procedure; and accessories, including IRED localization probes, navigated RF ablators, and navigated ultrasonic aspirators. Its system consists of a software architecture that allows the surgeon to display a 3D view of the liver. Its system is used in various open liver surgery applications, including hepatic resection, open ablation, open biopsy, living donor transplant, cyst removal, and tumor removal. Pathfinder Technologies was founded in 2004 and is based in Nashville, Tennessee.
SwingPal
Seed Round in 2012
SwingPal, LLC is a company based in Franklin, Tennessee, that operates an innovative online platform for learning golf. Established in 2010, the platform connects golfers with instructors through web and mobile access. Users can record their swings using a smartphone and upload the videos to their SwingPal accounts. They then receive detailed feedback, including annotated video and audio analysis from golf professionals, along with additional instructional content. This service is designed to help golfers improve their skills and modify their gameplay effectively.
NuSirt Sciences, Inc. is a biotechnology company based in Nashville, Tennessee, that focuses on developing innovative products for metabolic diseases linked to over-nutrition, such as obesity and diabetes. Established in 2007, the company has created a technology platform that combines natural compounds with pharmaceutical agents to activate sirtuin pathways, aiming to prevent and treat chronic conditions associated with aging. Its flagship product, NS-0100, combines the natural compound leucine with a low dose of metformin to address type 2 diabetes, particularly for patients who experience gastrointestinal side effects from standard metformin treatment. NuSirt is currently conducting Phase 2 clinical trials to determine the optimal dosage of NS-0100. The company has filed eleven patent applications related to its technologies, with two patents already issued, and has successfully completed four clinical studies alongside various pre-clinical investigations.
MedCenterDisplay
Seed Round in 2012
MedCenterDisplay, LLC specializes in digital patient engagement solutions for hospitals and clinics throughout the United States. Based in Brentwood, Tennessee, the company offers a comprehensive range of services, including digital signage, online marketing, social media management, and application development. These solutions are designed to enhance patient satisfaction, reduce avoidable readmissions, and improve healthcare-related metrics such as HCAHPS scores. MedCenterDisplay's digital signage systems effectively communicate with patients and their families in healthcare facilities, providing engaging content while they wait for services. The company's offerings also encompass search engine optimization, reputation management, and video production, all aimed at empowering healthcare organizations to connect with their patients more effectively. Originally incorporated as AMS, LLC in 2007, MedCenterDisplay operates as a subsidiary of PatientPoint, LLC as of November 2016.
Diabetes Care Group
Venture Round in 2012
Diabetes Care Group, Inc. is a healthcare provider specializing in diabetes clinical care services for individuals with diabetes and metabolic diseases. Founded in 1986 and based in Jackson, Mississippi, the company integrates a multidisciplinary approach that includes medical management, patient education, behavioral modification, and individualized nutrition counseling. Their services are designed to enhance patient self-management and improve clinical outcomes while also aiming to reduce overall medical and social costs associated with diabetes. The company employs a team of experienced professionals, including board-certified physicians, registered nurse educators, registered dieticians, and medical assistants, all dedicated to delivering effective diabetes care. Diabetes Care Group has established a track record of significant improvements in health outcomes for patients facing the challenges of diabetes.
OnFocus Healthcare
Venture Round in 2012
OnFocus Healthcare, originally established in 1985 as m21partners, transformed in 2008 into a provider of business execution software solutions for the healthcare sector. The company specializes in enterprise performance management (EPM) software and support services designed to enhance operational efficiency within healthcare organizations. Its flagship product, onFocus epm™, enables hospitals to improve patient care by streamlining processes, thereby ensuring that care is delivered more efficiently and cost-effectively. Through its software and advisory services, OnFocus Healthcare aims to elevate the performance and execution success of healthcare providers by at least 20%. The company's commitment is to support healthcare executives, managers, and staff in achieving their organizational goals and enhancing overall patient outcomes.
Pathfinder Technologies
Seed Round in 2012
Pathfinder Technologies (formerly Pathfinder Therapeutics, Inc.), a medical device company, engages in the design, development, and manufacture of solutions in the field of navigated abdominal surgery. The company provides an integrated intra-operative image guidance system for open liver surgical procedure; and accessories, including IRED localization probes, navigated RF ablators, and navigated ultrasonic aspirators. Its system consists of a software architecture that allows the surgeon to display a 3D view of the liver. Its system is used in various open liver surgery applications, including hepatic resection, open ablation, open biopsy, living donor transplant, cyst removal, and tumor removal. Pathfinder Technologies was founded in 2004 and is based in Nashville, Tennessee.
Diagnovus
Seed Round in 2011
Diagnovus, established in 2011 and located in Nashville, TN, is dedicated to advancing patient health through innovative molecular diagnostics. The company focuses on developing diagnostic tests aimed at rare forms of cancer, including pediatric cancers, to enhance the decision-making process for physicians, patients, and their families. By prioritizing evidence-based solutions, Diagnovus aims to improve treatment outcomes and facilitate more effective care. Their commitment to serving the healthcare community reflects a passion for enhancing the quality of life for patients while also promoting a more efficient allocation of healthcare resources.
Industrial Ceramic Solutions
Seed Round in 2011
Industrial Ceramic Solutions, LLC is a manufacturer specializing in air pollution control equipment, particularly for industrial and diesel exhaust filter applications. Founded in 1997 and based in Oak Ridge, Tennessee, the company offers a range of products including diesel particulate filters, high-temperature exhaust filters, and devices for air, gas, odor, and smoke control. The founder, Richard Nixdorf, has over 40 years of experience in materials development, particularly in ceramics, metals, and polymers. His work led to innovations such as a silicon carbide fiber that can rapidly convert microwave energy to thermal energy, initially aimed at addressing regulatory requirements for diesel engine particulate filters. Although early attempts to utilize microwave energy for filter regeneration faced challenges, the company's products gained significant interest from major automotive suppliers. In 2007, a Fortune 100 company secured an exclusive license to manufacture the diesel particulate filter developed by ICS, although this agreement concluded in 2008 due to market conditions. Today, Industrial Ceramic Solutions continues to focus on advanced filtration technologies to meet evolving industrial needs.
Panopto
Venture Round in 2011
Panopto, Inc. is a video software company that provides a comprehensive platform for video content management tailored for corporate and educational markets globally. Founded in 2007 and headquartered in Seattle, Washington, with additional offices in cities such as Pittsburgh, London, Sydney, and Hong Kong, Panopto specializes in creating searchable video libraries that preserve institutional knowledge. The platform encompasses a variety of functionalities, including video streaming, analytics, accessibility features, and live broadcasting capabilities. It supports users in recording and editing videos, facilitating employee training, onboarding, and live events for enterprises, as well as enhancing educational experiences through lecture capture and active learning. Panopto has established itself as a leader in video capture software and content management systems, recognized for its innovation and rapid growth within the industry.
OnFocus Healthcare
Series B in 2010
OnFocus Healthcare, originally established in 1985 as m21partners, transformed in 2008 into a provider of business execution software solutions for the healthcare sector. The company specializes in enterprise performance management (EPM) software and support services designed to enhance operational efficiency within healthcare organizations. Its flagship product, onFocus epm™, enables hospitals to improve patient care by streamlining processes, thereby ensuring that care is delivered more efficiently and cost-effectively. Through its software and advisory services, OnFocus Healthcare aims to elevate the performance and execution success of healthcare providers by at least 20%. The company's commitment is to support healthcare executives, managers, and staff in achieving their organizational goals and enhancing overall patient outcomes.