Mountain Group Capital

Mountain Group Capital, LLC is a venture capital and private equity firm founded in 2002 and based in Nashville, Tennessee. The firm specializes in seed, early-stage, venture equity, buyouts, growth capital, and later-stage investments, primarily targeting the life sciences, animal health, and technology sectors. Within life sciences, it emphasizes MedTech, medical devices, diagnostics, nutraceuticals, and expedited drug development. In the animal health sector, the firm focuses on technologies that enhance companion animal health and agricultural practices. Mountain Group Capital also invests in disruptive technologies that feature innovative business models with manageable development risk and a swift path to market. The firm seeks investment opportunities in North America, particularly in the Southeastern United States and Tennessee, typically targeting companies with revenues between $1 million and $50 million. It generally prefers to acquire minority interests in venture capital investments while aiming for controlling interests in buyout transactions.

Joe Cook III

Managing Director

Byron Smith

Managing Director

66 past transactions

MiNDERA Corporation

Convertible Note in 2024
MiNDERA Corporation specializes in the development of non-invasive molecular testing devices aimed at diagnosing skin cancer and other skin diseases. The company's innovative products include a micro-needle array patch that allows for pain-free and minimally invasive extraction of biomarkers such as RNA, DNA, and proteins from the skin, eliminating the need for traditional skin biopsies. Additionally, MiNDERA is working on a whole transcriptome extraction patch and a skin microbiome extraction patch for various research applications. Founded in 2013, the company is headquartered in Palo Alto, California.

PinkDx

Series A in 2024
PinkDx is a biotechnology company.

Circular Genomics

Series A in 2024
Circular Genomics is a company based in Albuquerque, New Mexico, specializing in the development of circular RNA diagnostics to enhance precision medicine in the treatment of neurological and psychiatric conditions. Founded in 2021, the company aims to improve the diagnosis and treatment of depressive disorders by utilizing circular RNA as a novel biomarker. This innovative approach allows for evidence-based treatment strategies, significantly reducing the time required for patients to achieve a therapeutic response. By focusing on the potential of circular RNA, Circular Genomics is positioning itself as a leader in the field of psychiatric and neurological diagnostics, enabling healthcare professionals to better address complex mental health issues.

Airvet

Series B in 2023
Airvet Inc. is a veterinary telemedicine platform that connects pet owners with veterinarians through a user-friendly application. Founded in 2018 and based in Beverly Hills, California, Airvet enables pet parents to schedule virtual appointments for general health checkups, medical inquiries, and behavioral concerns via live video, audio, and chat. This innovative approach fosters ongoing relationships between veterinarians and clients, enhancing the continuity of care that was previously difficult to maintain. By providing affordable access to veterinary services, Airvet aims to improve the health and well-being of pets, while also driving clinic revenue and integrating veterinarians into a modern veterinary community.

Vytelle

Series B in 2023
Vytelle, LLC is a biotechnology company based in Hermiston, Oregon, focused on enhancing livestock genetics for beef and dairy producers. Founded in 2015 and originally named Cogent IVF, Vytelle specializes in ovum pick-up and embryo production services, which include implantation and post-in vitro fertilization consultation. The company utilizes an integrated technology platform that employs reproductive technology and a proprietary culture system free from fetal calf serum. This innovative approach produces freezable embryos, allowing commercial producers to achieve sustainable genetic gains across generations. Vytelle aims to reshape the cattle industry by optimizing herd performance through advanced reproductive techniques.

Silicon Ranch

Private Equity Round in 2023
Silicon Ranch Corporation is a Nashville-based company that develops, owns, and operates utility-scale solar power projects across the United States. Founded in 2010, it specializes in delivering cost-effective and innovative solar energy solutions for a diverse range of clients, including utilities, military facilities, and commercial businesses. The company is committed to long-term ownership of its projects, which reinforces its dedication to partners and the communities it serves. In addition to its solar energy initiatives, Silicon Ranch operates a regional energy-training center that provides education and training in solar installation, maintenance, and weatherization. Through its efforts, the company aims to promote economic development and create job opportunities while contributing to the transition to sustainable energy sources.

AngelEye Health

Series B in 2022
AngelEye Health is a developer of a tele-engagement platform designed to integrate parents into the care team during their child's stay in neonatal intensive care units (NICUs) and pediatric units. The company offers a comprehensive, HIPAA-compliant solution that includes bedside cameras, patient communication tools, feeding management systems, and targeted educational resources. These services enhance care team workflows and provide families with improved access to their child's treatment plans and progress through any connected device. By fostering meaningful care experiences, AngelEye Health aims to improve family satisfaction, enhance care delivery efficiency, and ultimately elevate the quality of care for patients.

Verility

Series A in 2022
Verility is focused on enhancing reproductive performance in livestock to meet the growing demand for meat protein and improve food sustainability. The company develops veterinary medical devices that provide accurate and cost-effective analysis of animal semen samples at the point of care, along with ovulation prediction. Utilizing advanced image recognition and artificial intelligence, Verility's products enable animal-side sperm quality assessments and rapid evaluation of cell morphology. This technology assists livestock producers and breeders in determining the optimal timing for breeding, thereby improving overall efficiency in animal reproduction.

Targan

Series C in 2022
TARGAN is a bio-systems company dedicated to enhancing animal health and productivity in the poultry, livestock, and aquaculture sectors. It is developing an innovative vaccination system that aims to replace traditional mass spray methods with a more precise approach, ensuring that every newly hatched chick receives the appropriate vaccine. This technology not only aims to improve immunization rates but also enhances the natural immune response to diseases, leading to better overall flock health. By increasing vaccination accuracy and consistency, TARGAN's solution helps reduce reliance on antibiotics, contributing to cleaner and healthier livestock. The company's focus on improving animal well-being and operational efficiency positions it as a leader in the field of animal production.

Silicon Ranch

Private Equity Round in 2022
Silicon Ranch Corporation is a Nashville-based company that develops, owns, and operates utility-scale solar power projects across the United States. Founded in 2010, it specializes in delivering cost-effective and innovative solar energy solutions for a diverse range of clients, including utilities, military facilities, and commercial businesses. The company is committed to long-term ownership of its projects, which reinforces its dedication to partners and the communities it serves. In addition to its solar energy initiatives, Silicon Ranch operates a regional energy-training center that provides education and training in solar installation, maintenance, and weatherization. Through its efforts, the company aims to promote economic development and create job opportunities while contributing to the transition to sustainable energy sources.

Circular Genomics

Seed Round in 2021
Circular Genomics is a company based in Albuquerque, New Mexico, specializing in the development of circular RNA diagnostics to enhance precision medicine in the treatment of neurological and psychiatric conditions. Founded in 2021, the company aims to improve the diagnosis and treatment of depressive disorders by utilizing circular RNA as a novel biomarker. This innovative approach allows for evidence-based treatment strategies, significantly reducing the time required for patients to achieve a therapeutic response. By focusing on the potential of circular RNA, Circular Genomics is positioning itself as a leader in the field of psychiatric and neurological diagnostics, enabling healthcare professionals to better address complex mental health issues.

Targan

Series B in 2021
TARGAN is a bio-systems company dedicated to enhancing animal health and productivity in the poultry, livestock, and aquaculture sectors. It is developing an innovative vaccination system that aims to replace traditional mass spray methods with a more precise approach, ensuring that every newly hatched chick receives the appropriate vaccine. This technology not only aims to improve immunization rates but also enhances the natural immune response to diseases, leading to better overall flock health. By increasing vaccination accuracy and consistency, TARGAN's solution helps reduce reliance on antibiotics, contributing to cleaner and healthier livestock. The company's focus on improving animal well-being and operational efficiency positions it as a leader in the field of animal production.

MiNDERA Corporation

Series A in 2021
MiNDERA Corporation specializes in the development of non-invasive molecular testing devices aimed at diagnosing skin cancer and other skin diseases. The company's innovative products include a micro-needle array patch that allows for pain-free and minimally invasive extraction of biomarkers such as RNA, DNA, and proteins from the skin, eliminating the need for traditional skin biopsies. Additionally, MiNDERA is working on a whole transcriptome extraction patch and a skin microbiome extraction patch for various research applications. Founded in 2013, the company is headquartered in Palo Alto, California.

Advanced Animal Diagnostics

Venture Round in 2021
Advanced Animal Diagnostics, Inc. focuses on the research, development, and commercialization of on-farm diagnostic tools aimed at the early detection of subclinical mastitis in dairy cows. Based in Durham, North Carolina, the company offers products such as the QScout Farm Lab, an analyzer system that identifies infections in dairy cows before symptoms manifest, and the QScout Milk Leukocyte Differential rapid test, which analyzes milk to detect and differentiate white blood cells indicative of mastitis. Additionally, Advanced Animal Diagnostics provides solutions like QuickSmear, a rapid differential slide that aids in animal research, and the SCC+ System for early mastitis detection. These diagnostic tools are designed to enhance animal health management, benefiting veterinarians and livestock producers by enabling timely detection of infections and supporting informed treatment decisions. Founded in 2001, the company aims to improve the overall health and productivity of production animals.

Silicon Ranch

Funding Round in 2020
Silicon Ranch Corporation is a Nashville-based company that develops, owns, and operates utility-scale solar power projects across the United States. Founded in 2010, it specializes in delivering cost-effective and innovative solar energy solutions for a diverse range of clients, including utilities, military facilities, and commercial businesses. The company is committed to long-term ownership of its projects, which reinforces its dedication to partners and the communities it serves. In addition to its solar energy initiatives, Silicon Ranch operates a regional energy-training center that provides education and training in solar installation, maintenance, and weatherization. Through its efforts, the company aims to promote economic development and create job opportunities while contributing to the transition to sustainable energy sources.

AN2 Therapeutics

Series A in 2019
AN2 Therapeutics, Inc. is a biopharmaceutical company based in Menlo Park, California, founded in 2017. The company is dedicated to the research, development, and commercialization of innovative medicines aimed at addressing infectious diseases. AN2 Therapeutics is focused on developing epetraborole, a once-daily oral treatment for patients suffering from chronic non-tuberculous mycobacterial lung disease, which represents a significant unmet medical need. Additionally, the company has established a strategic partnership with Brii Biosciences to enhance its development efforts.

Targan

Series A in 2019
TARGAN is a bio-systems company dedicated to enhancing animal health and productivity in the poultry, livestock, and aquaculture sectors. It is developing an innovative vaccination system that aims to replace traditional mass spray methods with a more precise approach, ensuring that every newly hatched chick receives the appropriate vaccine. This technology not only aims to improve immunization rates but also enhances the natural immune response to diseases, leading to better overall flock health. By increasing vaccination accuracy and consistency, TARGAN's solution helps reduce reliance on antibiotics, contributing to cleaner and healthier livestock. The company's focus on improving animal well-being and operational efficiency positions it as a leader in the field of animal production.

PhaseBio

Series D in 2018
PhaseBio is a clinical-stage biopharmaceutical company focused on developing innovative therapies for endocrine and metabolic disorders, as well as cardiovascular diseases. The company leverages its proprietary elastin-like polypeptides (ELPs) technology to enhance the stability, bioavailability, and efficacy of proteins and peptides. Its lead candidate, PB1023, is in a phase 2b clinical trial for managing hyperglycemia in type 2 diabetes, with potential applications in obesity. Additionally, PhaseBio is advancing Vasomera, a candidate in phase 1 trials aimed at treating pulmonary arterial hypertension and heart failure. The company is also exploring PB2452, a novel reversal agent for the antiplatelet drug ticagrelor, and PB1046 for pulmonary arterial hypertension. With a commitment to addressing unmet medical needs, PhaseBio is headquartered in Malvern, Pennsylvania.

ORIG3N

Series B in 2018
ORIG3N, Inc. is a biotechnology company focused on developing innovative treatments for rare genetically inherited diseases, particularly targeting conditions related to the heart, liver, and neurodegeneration. Founded in 2014 and based in Boston, Massachusetts, ORIG3N utilizes induced pluripotent stem cell technology that allows for the differentiation of cells into any type found in the body. This technology is employed to test drug efficacy, screen for medication toxicity, and create personalized treatment pathways. The company offers a range of products, including LifeProfiles, which provides genetic insights related to fitness, metabolism, and exercise recovery; the Run DNA test for optimizing running performance; AURA, which assesses skin health; and Life Capsule, a repository for blood cells aimed at regenerative medicine development.

NeuroTronik

Series B in 2017
NeuroTronik, spun out of medical technology incubator Synecor, is developing a medical device that could take the place of drugs currently used to heart failure. Read more about the company's technology,

Boragen

Series A in 2017
Boragen Inc. is a biotechnology company based in Durham, North Carolina, founded in 2015. The company specializes in developing multi-functional small molecule boron solutions for applications in crop protection, animal health, and human health. Boragen's product pipeline includes BAG8, a boron-based multisite fungicide aimed at crop protection, and BN2266, a fungicide that targets mRNA processing. Additionally, the company is working on a dual-function nematicide-fungicide for root protection and endo-parasiticides designed to overcome resistance. Boragen's innovative synthetic chemistry platform focuses on creating next-generation fungicides that support sustainable farming by minimizing the risk of fungicide resistance and reducing chemical usage while ensuring efficacy and performance.

G1 Therapeutics

Series C in 2016
G1 Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of innovative small molecule therapeutics for cancer treatment. The company is advancing several key drug candidates, including trilaciclib, an intravenous cyclin-dependent kinases (CDK) 4/6 inhibitor currently in Phase 1b/2 trials for extensive-stage small cell lung cancer (SCLC) and Phase 2 trials for first-line SCLC and metastatic triple-negative breast cancer. Additionally, G1 Therapeutics is developing lerociclib, an oral CDK4/6 inhibitor in Phase 1b/2a trials for breast cancer and Phase 1b trials for non-small cell lung cancer, as well as rintodestrant, an oral selective estrogen receptor degrader in Phase I/2 trials. The company partners with Quantum Leap Healthcare Collaborative to explore trilaciclib for neoadjuvant treatment of locally advanced breast cancer. Founded in 2008 and based in Research Triangle Park, North Carolina, G1 Therapeutics aims to address unmet needs in oncology through its novel therapeutic approaches.

ORIG3N

Series A in 2015
ORIG3N, Inc. is a biotechnology company focused on developing innovative treatments for rare genetically inherited diseases, particularly targeting conditions related to the heart, liver, and neurodegeneration. Founded in 2014 and based in Boston, Massachusetts, ORIG3N utilizes induced pluripotent stem cell technology that allows for the differentiation of cells into any type found in the body. This technology is employed to test drug efficacy, screen for medication toxicity, and create personalized treatment pathways. The company offers a range of products, including LifeProfiles, which provides genetic insights related to fitness, metabolism, and exercise recovery; the Run DNA test for optimizing running performance; AURA, which assesses skin health; and Life Capsule, a repository for blood cells aimed at regenerative medicine development.

splitsecnd

Venture Round in 2015
splitsecnd offers a portable plug-in vehicle connectivity device that enhances driver safety and emergency response. The device plugs into the 12V lighter outlet of any car and utilizes airbag sensor technology to detect crashes. Upon impact, it automatically alerts emergency services, connects the user to a live operator, dispatches help to the location, and notifies designated emergency contacts. Additionally, the device can be manually activated in emergencies or roadside breakdowns. Beyond emergency response, splitsecnd features comprehensive trip analytics and GPS capabilities, allowing users to track routes, promote safe driving habits, and locate parked vehicles. This device is designed for a wide range of drivers, including seniors and teens, providing peace of mind without the need for a cell phone.

Restore Medical Solutions

Series A in 2015
Restore Medical Solutions, Inc. is a medical device company based in Memphis, Tennessee, founded in 2012. The company specializes in manufacturing modular sterilization tray systems designed for use in hospitals and surgery centers. These systems aim to reduce the risk of surgical site infections by minimizing contamination from medical instruments. By enhancing efficiency and safety in healthcare settings, Restore Medical Solutions helps surgical departments improve the quality of care while also lowering costs. The innovative design of its products contributes to better operational productivity and supports the overall goal of delivering high-standard healthcare.

MedCenterDisplay

Series B in 2015
MedCenterDisplay, LLC specializes in digital patient satisfaction and engagement solutions for hospitals and clinics across the United States. Founded in 2007 and based in Brentwood, Tennessee, the company offers a comprehensive range of services, including digital signage, online marketing, and application development, aimed at enhancing patient engagement and satisfaction. Their innovative digital signage systems are designed to effectively communicate with patients and their families while they wait for medical services. Additionally, MedCenterDisplay provides online marketing solutions such as search engine optimization, reputation management, social media support, and website development. The company's services are tailored to improve healthcare outcomes, reduce avoidable readmissions, and enhance patient experience metrics like HCAHPS. MedCenterDisplay operates as a subsidiary of PatientPoint, LLC, further solidifying its role in the healthcare marketing landscape.

Nusirt

Series C in 2015
NuSirt Sciences, Inc. is a biotechnology company dedicated to developing innovative treatments for metabolic diseases related to over-nutrition, such as obesity and type 2 diabetes. The company has created a unique technology platform that combines natural compounds with pharmaceutical agents to activate sirtuin pathways, aiming to prevent and treat chronic conditions associated with aging. Its lead product, NS-0100, merges the natural compound leucine with a low dose of metformin, which is commonly used for managing early type 2 diabetes but often causes gastrointestinal side effects that limit patient tolerance. Currently, NuSirt is conducting Phase 2 clinical trials to determine the most effective dosage of NS-0100. The company has filed eleven patent applications, with two already issued, and has successfully completed several clinical and pre-clinical studies based on its proprietary technologies. Founded in 2007 and based in Nashville, Tennessee, NuSirt Sciences continues to focus on advancing solutions for chronic diseases, particularly those related to metabolic dysfunction.

Myomo

Series B in 2015
Myomo, Inc. is a medical technology company based in Cambridge, Massachusetts, specializing in wearable medical robotics. Founded in 2004, Myomo develops myoelectric orthotics, particularly the MyoPro, a myoelectric-controlled upper limb brace designed to assist individuals with neuromuscular disorders, including those resulting from strokes, spinal cord injuries, and other neurological conditions. The MyoPro supports weak or paralyzed arms, facilitating daily activities at home and in the community. The company also offers the mPower 1000, a lightweight functional arm brace that aids in restoring movement, as well as a suite of therapeutic programs, including the PERL technique and myGames, which leverage virtual reality to enhance rehabilitation. Myomo's products are distributed through orthotics and prosthetics providers, rehabilitation hospitals, and the Veterans Health Administration, serving medical professionals, patients, and caregivers across the United States.

Contego Medical

Series B in 2015
Contego Medical, Inc. specializes in developing embolic protection devices aimed at treating cardiovascular and endovascular diseases. The company offers a range of innovative products, including angioplasty balloons and stent delivery catheters, which integrate embolic protection technology. This portfolio includes systems such as the Paladin Carotid PTA Balloon System, the Vanguard IEP Peripheral Balloon Angioplasty System, and the Excipio SV Thrombectomy Device, all designed to enhance patient outcomes and procedural efficiency during treatments for conditions like carotid artery disease, peripheral artery disease, and deep vein thrombosis. Founded in 2005 and headquartered in Raleigh, North Carolina, Contego Medical also maintains an office in Curitiba, Brazil, reflecting its commitment to addressing the needs of healthcare professionals in cardiovascular procedures.

G1 Therapeutics

Series B in 2015
G1 Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of innovative small molecule therapeutics for cancer treatment. The company is advancing several key drug candidates, including trilaciclib, an intravenous cyclin-dependent kinases (CDK) 4/6 inhibitor currently in Phase 1b/2 trials for extensive-stage small cell lung cancer (SCLC) and Phase 2 trials for first-line SCLC and metastatic triple-negative breast cancer. Additionally, G1 Therapeutics is developing lerociclib, an oral CDK4/6 inhibitor in Phase 1b/2a trials for breast cancer and Phase 1b trials for non-small cell lung cancer, as well as rintodestrant, an oral selective estrogen receptor degrader in Phase I/2 trials. The company partners with Quantum Leap Healthcare Collaborative to explore trilaciclib for neoadjuvant treatment of locally advanced breast cancer. Founded in 2008 and based in Research Triangle Park, North Carolina, G1 Therapeutics aims to address unmet needs in oncology through its novel therapeutic approaches.

ORIG3N

Venture Round in 2015
ORIG3N, Inc. is a biotechnology company focused on developing innovative treatments for rare genetically inherited diseases, particularly targeting conditions related to the heart, liver, and neurodegeneration. Founded in 2014 and based in Boston, Massachusetts, ORIG3N utilizes induced pluripotent stem cell technology that allows for the differentiation of cells into any type found in the body. This technology is employed to test drug efficacy, screen for medication toxicity, and create personalized treatment pathways. The company offers a range of products, including LifeProfiles, which provides genetic insights related to fitness, metabolism, and exercise recovery; the Run DNA test for optimizing running performance; AURA, which assesses skin health; and Life Capsule, a repository for blood cells aimed at regenerative medicine development.

Lineagen

Series C in 2015
Lineagen, Inc. is a genetics diagnostic company based in Salt Lake City, Utah, that specializes in genetic testing and clinical information services for neurodevelopmental disorders, particularly autism spectrum disorders (ASDs). Founded in 2002, Lineagen offers several key products, including FirstStepDx PLUS, a chromosomal microarray platform designed to identify genomic changes associated with autism, and NextStepDx PLUS, a genetic sequencing test that detects small genomic alterations. Additionally, the company provides M-CHAT.org, an online tool for developmental screening. Lineagen aims to improve outcomes for individuals affected by complex diseases through early diagnosis and intervention, leveraging extensive proprietary research and access to the Utah Population Database to enhance its understanding of genetic contributions to these conditions. As of August 2020, Lineagen operates as a subsidiary of Bionano Genomics, Inc.

Clearside Biomedical

Series B in 2014
Clearside Biomedical, Inc. is a biopharmaceutical company focused on developing treatments for serious eye diseases with the aim of restoring and preserving vision. Founded in 2011 and headquartered in Alpharetta, Georgia, the company specializes in a proprietary ocular microinjection platform that allows for targeted delivery of therapeutic products to specific compartments of the eye. This innovative approach includes the use of the SCS Microinjector for administering therapies directly into the suprachoroidal space, enabling a non-surgical, repeatable procedure. Among its product pipeline, Clearside is developing XIPERE, a triamcinolone acetonide injectable suspension for macular edema, and CLS-AX, an axitinib for suprachoroidal injection. The company is dedicated to advancing pharmacological therapies for sight-threatening conditions by ensuring precise and effective treatment delivery.

MedCenterDisplay

Venture Round in 2014
MedCenterDisplay, LLC specializes in digital patient satisfaction and engagement solutions for hospitals and clinics across the United States. Founded in 2007 and based in Brentwood, Tennessee, the company offers a comprehensive range of services, including digital signage, online marketing, and application development, aimed at enhancing patient engagement and satisfaction. Their innovative digital signage systems are designed to effectively communicate with patients and their families while they wait for medical services. Additionally, MedCenterDisplay provides online marketing solutions such as search engine optimization, reputation management, social media support, and website development. The company's services are tailored to improve healthcare outcomes, reduce avoidable readmissions, and enhance patient experience metrics like HCAHPS. MedCenterDisplay operates as a subsidiary of PatientPoint, LLC, further solidifying its role in the healthcare marketing landscape.

Castle Biosciences

Venture Round in 2014
Castle Biosciences, Inc. is a commercial-stage biotechnology company headquartered in Friendswood, Texas, specializing in diagnostic and prognostic tests for dermatological cancers. The company develops innovative genomic tests to aid physicians and patients in making informed treatment decisions. Its flagship product, DecisionDx-Melanoma, is a multi-gene expression profile test designed to identify stage I and II melanoma patients at high risk of metastasis. Additionally, Castle Biosciences offers the DecisionDx-UM test, which assesses the risk of metastasis in patients with uveal melanoma, a rare eye cancer. The company is also advancing two proprietary tests aimed at addressing cutaneous squamous cell carcinoma and suspicious pigmented lesions, both of which represent significant clinical needs in dermatological oncology. Through its products, Castle Biosciences aims to provide personalized and actionable genomic information, thereby enhancing cancer diagnosis and management.

InvisionHeart

Series A in 2014
InvisionHeart is a company focused on enhancing cardiac care through its innovative hardware and software system designed to capture and manage cardiac data. Originating from research conducted by physicians and engineers at Vanderbilt University, the technology addresses real-world clinical challenges faced by heart patients. InvisionHeart offers a mobile electrocardiograph system that allows a network of healthcare professionals, including physicians, nurses, and technicians, to securely access and annotate patient electrocardiogram tracings. The company's leadership, consisting of experienced professionals in both software and hardware development, along with a strong clinical advisory team, is dedicated to improving the care of heart patients in diverse environments.

Nusirt

Series B in 2014
NuSirt Sciences, Inc. is a biotechnology company dedicated to developing innovative treatments for metabolic diseases related to over-nutrition, such as obesity and type 2 diabetes. The company has created a unique technology platform that combines natural compounds with pharmaceutical agents to activate sirtuin pathways, aiming to prevent and treat chronic conditions associated with aging. Its lead product, NS-0100, merges the natural compound leucine with a low dose of metformin, which is commonly used for managing early type 2 diabetes but often causes gastrointestinal side effects that limit patient tolerance. Currently, NuSirt is conducting Phase 2 clinical trials to determine the most effective dosage of NS-0100. The company has filed eleven patent applications, with two already issued, and has successfully completed several clinical and pre-clinical studies based on its proprietary technologies. Founded in 2007 and based in Nashville, Tennessee, NuSirt Sciences continues to focus on advancing solutions for chronic diseases, particularly those related to metabolic dysfunction.

Nusirt

Series A in 2014
NuSirt Sciences, Inc. is a biotechnology company dedicated to developing innovative treatments for metabolic diseases related to over-nutrition, such as obesity and type 2 diabetes. The company has created a unique technology platform that combines natural compounds with pharmaceutical agents to activate sirtuin pathways, aiming to prevent and treat chronic conditions associated with aging. Its lead product, NS-0100, merges the natural compound leucine with a low dose of metformin, which is commonly used for managing early type 2 diabetes but often causes gastrointestinal side effects that limit patient tolerance. Currently, NuSirt is conducting Phase 2 clinical trials to determine the most effective dosage of NS-0100. The company has filed eleven patent applications, with two already issued, and has successfully completed several clinical and pre-clinical studies based on its proprietary technologies. Founded in 2007 and based in Nashville, Tennessee, NuSirt Sciences continues to focus on advancing solutions for chronic diseases, particularly those related to metabolic dysfunction.

Diagnovus

Seed Round in 2013
Diagnovus, founded in 2011 and located in Nashville, TN, specializes in molecular diagnostics aimed at rare cancers, including pediatric forms. The company is committed to developing innovative diagnostic tests that enhance the decision-making process for physicians, patients, and families dealing with challenging health conditions. By focusing on evidence-based products, Diagnovus aims to improve patient outcomes, support healthcare providers in delivering more effective care, and promote the efficient use of healthcare resources. Through its dedication to improving health and treatment quality, Diagnovus seeks to make a significant impact in the field of molecular diagnostics.

G1 Therapeutics

Series A in 2013
G1 Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of innovative small molecule therapeutics for cancer treatment. The company is advancing several key drug candidates, including trilaciclib, an intravenous cyclin-dependent kinases (CDK) 4/6 inhibitor currently in Phase 1b/2 trials for extensive-stage small cell lung cancer (SCLC) and Phase 2 trials for first-line SCLC and metastatic triple-negative breast cancer. Additionally, G1 Therapeutics is developing lerociclib, an oral CDK4/6 inhibitor in Phase 1b/2a trials for breast cancer and Phase 1b trials for non-small cell lung cancer, as well as rintodestrant, an oral selective estrogen receptor degrader in Phase I/2 trials. The company partners with Quantum Leap Healthcare Collaborative to explore trilaciclib for neoadjuvant treatment of locally advanced breast cancer. Founded in 2008 and based in Research Triangle Park, North Carolina, G1 Therapeutics aims to address unmet needs in oncology through its novel therapeutic approaches.

Diagnovus

Seed Round in 2013
Diagnovus, founded in 2011 and located in Nashville, TN, specializes in molecular diagnostics aimed at rare cancers, including pediatric forms. The company is committed to developing innovative diagnostic tests that enhance the decision-making process for physicians, patients, and families dealing with challenging health conditions. By focusing on evidence-based products, Diagnovus aims to improve patient outcomes, support healthcare providers in delivering more effective care, and promote the efficient use of healthcare resources. Through its dedication to improving health and treatment quality, Diagnovus seeks to make a significant impact in the field of molecular diagnostics.

Best ABT Molecular Imaging

Venture Round in 2013
ABT Molecular Imaging is a medical imaging company that specializes in the design, manufacture, and marketing of biomarker generator systems for positron emission tomography (PET). Headquartered in Knoxville, Tennessee, the company offers the BG-75 Biomarker Generator, which produces unit doses of molecular imaging drugs on demand, facilitating immediate use at the point of care. The generator incorporates features such as quality control tests and detailed dose records to ensure reliability and compliance. Founded by Ron and Lynda Nutt in 2006, ABT aims to enhance the global expansion of PET imaging by providing innovative solutions for pharmaceutical companies. Its products are distributed through a comprehensive network of sales and service partners.

SwingPal

Seed Round in 2013
SwingPal, LLC is an online platform based in Franklin, Tennessee, that specializes in providing golf instruction through a digital interface. Founded in 2010, it connects golfers with professional instructors via a user-friendly system accessible on both the web and mobile devices. Users can record their golf swings using their smartphones and upload these videos to their SwingPal accounts. The platform then offers detailed and annotated analyses, combining video feedback with audio commentary from golf professionals. This service aims to help users refine their skills and improve their overall game.

StreamWeaver

Series A in 2013
StreamWeaver is a software company based in Nashville, Tennessee, that specializes in developing innovative technology solutions. Its flagship product is a multi-angle mobile video application that allows users to connect and record videos together, automatically generating split-screen content. In addition to its video offerings, StreamWeaver provides a technology platform that facilitates the integration and streaming of data across various IT tools. This platform enables near real-time data connectivity with event-driven automation and comprehensive observability, aimed at reducing integration costs and enhancing productivity for clients.

Diagnovus

Seed Round in 2013
Diagnovus, founded in 2011 and located in Nashville, TN, specializes in molecular diagnostics aimed at rare cancers, including pediatric forms. The company is committed to developing innovative diagnostic tests that enhance the decision-making process for physicians, patients, and families dealing with challenging health conditions. By focusing on evidence-based products, Diagnovus aims to improve patient outcomes, support healthcare providers in delivering more effective care, and promote the efficient use of healthcare resources. Through its dedication to improving health and treatment quality, Diagnovus seeks to make a significant impact in the field of molecular diagnostics.

Pathfinder Technologies

Venture Round in 2013
Pathfinder Technologies (formerly Pathfinder Therapeutics, Inc.), a medical device company, engages in the design, development, and manufacture of solutions in the field of navigated abdominal surgery. The company provides an integrated intra-operative image guidance system for open liver surgical procedure; and accessories, including IRED localization probes, navigated RF ablators, and navigated ultrasonic aspirators. Its system consists of a software architecture that allows the surgeon to display a 3D view of the liver. Its system is used in various open liver surgery applications, including hepatic resection, open ablation, open biopsy, living donor transplant, cyst removal, and tumor removal. Pathfinder Technologies was founded in 2004 and is based in Nashville, Tennessee.

Diagnovus

Seed Round in 2013
Diagnovus, founded in 2011 and located in Nashville, TN, specializes in molecular diagnostics aimed at rare cancers, including pediatric forms. The company is committed to developing innovative diagnostic tests that enhance the decision-making process for physicians, patients, and families dealing with challenging health conditions. By focusing on evidence-based products, Diagnovus aims to improve patient outcomes, support healthcare providers in delivering more effective care, and promote the efficient use of healthcare resources. Through its dedication to improving health and treatment quality, Diagnovus seeks to make a significant impact in the field of molecular diagnostics.

American Hometown Media

Seed Round in 2013
American Hometown Media, Inc. is a digital media company based in Franklin, Tennessee, that specializes in connecting with American home cooks through its internet platform. Founded in 2011, the company continues the tradition of analog publishing by syndicating editorial content that celebrates hometown cooks to community newspapers, magazines, and various media outlets across the nation. Its offerings include Just A Pinch Recipes, a digital social network focused on recipes and coupons for home cooks, and Just A Pinch Syndicated Media, which delivers content related to home cooking and American culture to a wide audience. American Hometown Media leverages its roots in traditional media while embracing digital innovation, reaching approximately two million households weekly with its syndicated columns.

Pathfinder Technologies

Seed Round in 2013
Pathfinder Technologies (formerly Pathfinder Therapeutics, Inc.), a medical device company, engages in the design, development, and manufacture of solutions in the field of navigated abdominal surgery. The company provides an integrated intra-operative image guidance system for open liver surgical procedure; and accessories, including IRED localization probes, navigated RF ablators, and navigated ultrasonic aspirators. Its system consists of a software architecture that allows the surgeon to display a 3D view of the liver. Its system is used in various open liver surgery applications, including hepatic resection, open ablation, open biopsy, living donor transplant, cyst removal, and tumor removal. Pathfinder Technologies was founded in 2004 and is based in Nashville, Tennessee.

SwingPal

Seed Round in 2013
SwingPal, LLC is an online platform based in Franklin, Tennessee, that specializes in providing golf instruction through a digital interface. Founded in 2010, it connects golfers with professional instructors via a user-friendly system accessible on both the web and mobile devices. Users can record their golf swings using their smartphones and upload these videos to their SwingPal accounts. The platform then offers detailed and annotated analyses, combining video feedback with audio commentary from golf professionals. This service aims to help users refine their skills and improve their overall game.

StreamWeaver

Series A in 2013
StreamWeaver is a software company based in Nashville, Tennessee, that specializes in developing innovative technology solutions. Its flagship product is a multi-angle mobile video application that allows users to connect and record videos together, automatically generating split-screen content. In addition to its video offerings, StreamWeaver provides a technology platform that facilitates the integration and streaming of data across various IT tools. This platform enables near real-time data connectivity with event-driven automation and comprehensive observability, aimed at reducing integration costs and enhancing productivity for clients.

Best ABT Molecular Imaging

Series C in 2012
ABT Molecular Imaging is a medical imaging company that specializes in the design, manufacture, and marketing of biomarker generator systems for positron emission tomography (PET). Headquartered in Knoxville, Tennessee, the company offers the BG-75 Biomarker Generator, which produces unit doses of molecular imaging drugs on demand, facilitating immediate use at the point of care. The generator incorporates features such as quality control tests and detailed dose records to ensure reliability and compliance. Founded by Ron and Lynda Nutt in 2006, ABT aims to enhance the global expansion of PET imaging by providing innovative solutions for pharmaceutical companies. Its products are distributed through a comprehensive network of sales and service partners.

StreamWeaver

Seed Round in 2012
StreamWeaver is a software company based in Nashville, Tennessee, that specializes in developing innovative technology solutions. Its flagship product is a multi-angle mobile video application that allows users to connect and record videos together, automatically generating split-screen content. In addition to its video offerings, StreamWeaver provides a technology platform that facilitates the integration and streaming of data across various IT tools. This platform enables near real-time data connectivity with event-driven automation and comprehensive observability, aimed at reducing integration costs and enhancing productivity for clients.

Diagnovus

Seed Round in 2012
Diagnovus, founded in 2011 and located in Nashville, TN, specializes in molecular diagnostics aimed at rare cancers, including pediatric forms. The company is committed to developing innovative diagnostic tests that enhance the decision-making process for physicians, patients, and families dealing with challenging health conditions. By focusing on evidence-based products, Diagnovus aims to improve patient outcomes, support healthcare providers in delivering more effective care, and promote the efficient use of healthcare resources. Through its dedication to improving health and treatment quality, Diagnovus seeks to make a significant impact in the field of molecular diagnostics.

Pathfinder Technologies

Venture Round in 2012
Pathfinder Technologies (formerly Pathfinder Therapeutics, Inc.), a medical device company, engages in the design, development, and manufacture of solutions in the field of navigated abdominal surgery. The company provides an integrated intra-operative image guidance system for open liver surgical procedure; and accessories, including IRED localization probes, navigated RF ablators, and navigated ultrasonic aspirators. Its system consists of a software architecture that allows the surgeon to display a 3D view of the liver. Its system is used in various open liver surgery applications, including hepatic resection, open ablation, open biopsy, living donor transplant, cyst removal, and tumor removal. Pathfinder Technologies was founded in 2004 and is based in Nashville, Tennessee.

SwingPal

Seed Round in 2012
SwingPal, LLC is an online platform based in Franklin, Tennessee, that specializes in providing golf instruction through a digital interface. Founded in 2010, it connects golfers with professional instructors via a user-friendly system accessible on both the web and mobile devices. Users can record their golf swings using their smartphones and upload these videos to their SwingPal accounts. The platform then offers detailed and annotated analyses, combining video feedback with audio commentary from golf professionals. This service aims to help users refine their skills and improve their overall game.

Nusirt

Seed Round in 2012
NuSirt Sciences, Inc. is a biotechnology company dedicated to developing innovative treatments for metabolic diseases related to over-nutrition, such as obesity and type 2 diabetes. The company has created a unique technology platform that combines natural compounds with pharmaceutical agents to activate sirtuin pathways, aiming to prevent and treat chronic conditions associated with aging. Its lead product, NS-0100, merges the natural compound leucine with a low dose of metformin, which is commonly used for managing early type 2 diabetes but often causes gastrointestinal side effects that limit patient tolerance. Currently, NuSirt is conducting Phase 2 clinical trials to determine the most effective dosage of NS-0100. The company has filed eleven patent applications, with two already issued, and has successfully completed several clinical and pre-clinical studies based on its proprietary technologies. Founded in 2007 and based in Nashville, Tennessee, NuSirt Sciences continues to focus on advancing solutions for chronic diseases, particularly those related to metabolic dysfunction.

MedCenterDisplay

Seed Round in 2012
MedCenterDisplay, LLC specializes in digital patient satisfaction and engagement solutions for hospitals and clinics across the United States. Founded in 2007 and based in Brentwood, Tennessee, the company offers a comprehensive range of services, including digital signage, online marketing, and application development, aimed at enhancing patient engagement and satisfaction. Their innovative digital signage systems are designed to effectively communicate with patients and their families while they wait for medical services. Additionally, MedCenterDisplay provides online marketing solutions such as search engine optimization, reputation management, social media support, and website development. The company's services are tailored to improve healthcare outcomes, reduce avoidable readmissions, and enhance patient experience metrics like HCAHPS. MedCenterDisplay operates as a subsidiary of PatientPoint, LLC, further solidifying its role in the healthcare marketing landscape.

Diabetes Care Group

Venture Round in 2012
Diabetes Care Group, Inc. is a provider of specialized clinical care services for individuals with diabetes, based in Jackson, Mississippi. Founded in 1986, the company focuses on delivering an interdisciplinary model that integrates medical management, patient education, and behavioral modification. Their services include personalized counseling, diet and nutrition guidance, blood glucose monitoring, and point-of-care laboratory testing, all aimed at enhancing patient self-management and clinical outcomes. With a commitment to reducing the overall medical and social costs associated with diabetes, Diabetes Care Group employs a team of experienced professionals, including board-certified physicians, registered nurse educators, and registered dieticians. This integrated approach is backed by over ten years of research and clinical experience, demonstrating significant improvements in health outcomes for patients facing the challenges of diabetes.

OnFocus Healthcare

Venture Round in 2012
ONFocus Healthcare, originally established in 1985 as m21partners, transitioned in 2008 to focus on providing business execution software solutions specifically for the healthcare sector. The company specializes in enterprise performance management (EPM) software and support services designed to enhance the operational effectiveness of healthcare organizations. Their flagship product, onFocus epm™, facilitates improved patient care by enabling hospitals to track and manage plans, metrics, and resources more efficiently. By offering both software and advisory services, ONFocus Healthcare aims to boost the execution success and performance of healthcare providers by at least 20%, ultimately ensuring patients receive better, faster, and more cost-effective care.

Pathfinder Technologies

Seed Round in 2012
Pathfinder Technologies (formerly Pathfinder Therapeutics, Inc.), a medical device company, engages in the design, development, and manufacture of solutions in the field of navigated abdominal surgery. The company provides an integrated intra-operative image guidance system for open liver surgical procedure; and accessories, including IRED localization probes, navigated RF ablators, and navigated ultrasonic aspirators. Its system consists of a software architecture that allows the surgeon to display a 3D view of the liver. Its system is used in various open liver surgery applications, including hepatic resection, open ablation, open biopsy, living donor transplant, cyst removal, and tumor removal. Pathfinder Technologies was founded in 2004 and is based in Nashville, Tennessee.

Diagnovus

Seed Round in 2011
Diagnovus, founded in 2011 and located in Nashville, TN, specializes in molecular diagnostics aimed at rare cancers, including pediatric forms. The company is committed to developing innovative diagnostic tests that enhance the decision-making process for physicians, patients, and families dealing with challenging health conditions. By focusing on evidence-based products, Diagnovus aims to improve patient outcomes, support healthcare providers in delivering more effective care, and promote the efficient use of healthcare resources. Through its dedication to improving health and treatment quality, Diagnovus seeks to make a significant impact in the field of molecular diagnostics.

Industrial Ceramic Solutions

Seed Round in 2011
Industrial Ceramic Solutions, LLC, based in Oak Ridge, Tennessee, specializes in the development and manufacture of air pollution control equipment, particularly for industrial and diesel exhaust filter applications. Founded in 1997 by Richard Nixdorf, who possesses over 40 years of experience in advanced materials, the company initially focused on creating a microwave regenerated diesel particulate filter using patented silicon carbide fibers. These fibers were designed to rapidly convert microwave energy into thermal energy, facilitating the high-temperature cleaning required for diesel engine exhaust filters mandated by the US Clean Air Act. Although the microwave regeneration approach proved impractical, the company’s diesel particulate filter cartridge garnered significant attention from international automotive suppliers. In 2007, a Fortune 100 company licensed the technology, but this agreement ended in 2008 due to a downturn in the diesel engine market. Industrial Ceramic Solutions continues to innovate in air and gas filtration technologies, offering a range of products designed to control and eliminate pollutants effectively.

Panopto

Venture Round in 2011
Panopto, Inc. is a video software company that provides a comprehensive platform for video content management tailored for corporate and educational markets globally. Founded in 2007 and headquartered in Seattle, Washington, with additional offices in cities such as Pittsburgh, London, Sydney, and Hong Kong, Panopto specializes in creating searchable video libraries that preserve institutional knowledge. The platform encompasses a variety of functionalities, including video streaming, analytics, accessibility features, and live broadcasting capabilities. It supports users in recording and editing videos, facilitating employee training, onboarding, and live events for enterprises, as well as enhancing educational experiences through lecture capture and active learning. Panopto has established itself as a leader in video capture software and content management systems, recognized for its innovation and rapid growth within the industry.

OnFocus Healthcare

Series B in 2010
ONFocus Healthcare, originally established in 1985 as m21partners, transitioned in 2008 to focus on providing business execution software solutions specifically for the healthcare sector. The company specializes in enterprise performance management (EPM) software and support services designed to enhance the operational effectiveness of healthcare organizations. Their flagship product, onFocus epm™, facilitates improved patient care by enabling hospitals to track and manage plans, metrics, and resources more efficiently. By offering both software and advisory services, ONFocus Healthcare aims to boost the execution success and performance of healthcare providers by at least 20%, ultimately ensuring patients receive better, faster, and more cost-effective care.
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