Mystic Ventures
What do Peter Thiel, Kevin O’Leary, Tim Ferris, Sam Harris, Michael Pollan, Sting, and Tony Robbins all have in common? They are either advocates for or directly investing in psychedelic medicine and research. The past decade has ushered in a psychedelic renaissance, inspiring a massive push for research, decriminalization, and legalization of these powerful substances. There has been a radical shift in discussions of consciousness expansion, which has broken into the mainstream. With newfound, burgeoning support ranging from academia to medicine, government to business, there’s an extraordinary opportunity to tap into the commercial and social potential of this nascent space. Mystic Ventures believes the world would be much better if more people experienced the healing power of psychedelics. Mystic cares about mental health and human conditions. The fund’s goal is to draw on my experience as an entrepreneur and investor, backing pre-seed and seed-stage startups creating high-quality psychedelic experiences and treatments. I am starting Mystic to support founders who realize the healing power of psychedelics to elevate humanity’s consciousness. I will harness my broad network and abundance of resources to ensure the success of these ventures. Given my reach throughout the investing world and social media, as well as a growing network within the psychedelic space, I am confident that we will have outstanding deal flow and access to any emerging opportunities. We will draw on a wide range of industry experts, from medical professionals to academics, to validate startup theses, but the focus will be on investing in world-class, dynamic founders. Given how early this industry is, it’s difficult to pinpoint precisely how big the market opportunity is— but considering the large, ever-expanding applications of psychedelic medicines and therapies, the potential is nothing short of mind-boggling. The global market for drugs used in mental disorders was $70.1 billion in 2012. Just the antidepressant drug market was valued at $13.69b in 2015. More broadly, in 2019, mental health spending topped $225 Billion in the US alone. Two publicly traded psychedelic companies, both founded in the past five years, Compass Pathways and MindMed (which we were offered pre-IPO access to), have market capitalizations over $1 billion, and many more have nine-figure valuations. In contrast, the global legal marijuana market was valued at $17.7 billion in 2019. Thus, it’s hard to overstate how large and how quickly this space could grow. The priority is getting this fund to market as soon as possible, which is why we chose a Rolling Fund. Whenever possible, I will spin up SPVs for LPs that would like larger exposure to deals or when it's deemed appropriate to do follow-on investments.
Psylo is a drug development company that focuses on next-generation psychedelics. With psychedelic molecules as the starting point, our goal is to develop medicines that are widely available as improved treatments to currently available SSRI medications.
Spiritus Bioscience is a drug development company seeking to apply their proprietary drug-delivery technology to the Medicalized-Psilocybin market in Oregon
Awakn Life Sciences is a biotechnology company dedicated to developing and delivering psychedelic medicine aimed at treating addiction, with a primary focus on Alcohol Use Disorder (AUD). The company's team comprises chemists, scientists, psychiatrists, and psychologists who are working on the next generation of psychedelic drugs and therapies. By addressing AUD, a condition that affects millions worldwide and for which existing treatments are often insufficient, Awakn seeks to provide innovative therapeutic solutions for individuals struggling with addiction.
2A Biosciences is a pharmaceutical company founded in 2022 and based in California, USA. The company specializes in developing small molecule drugs aimed at treating inflammatory diseases through the use of 2A agonists, which target the serotonin system. Currently operating in stealth mode, 2A Biosciences is focused on advancing its innovative therapies to address unmet medical needs in the field of inflammation.
Sama Therapeutics is a developer of precision neuropsychiatry solutions that leverages artificial intelligence and machine learning to enhance the efficacy of clinical trials in the field of neuropsychiatry. The company focuses on preventing clinical trial failures and reducing associated costs by effectively profiling participants who are likely to respond to specific treatments. Utilizing advanced techniques such as generative AI and deep learning transformers, Sama Therapeutics processes multimodal data, including neural electroencephalogram (EEG), physiological electrocardiogram (ECG), multi-omics, and behavioral data. This approach enables the generation of interpretable and replicable models that synthesize and validate predictive biomarkers, ultimately aiming to improve the quality of psychiatric treatments available to clinicians.
Heading Health is a technology-enabled mental health platform focused on enhancing access to affordable mental health care. The platform provides personalized treatment solutions that utilize evidence-based therapeutics and innovative technologies, including Spravato, transcranial magnetic stimulation, telepsychiatry, and intramuscular ketamine. By offering these services, Heading Health aims to enable patients to experience meaningful improvements in their mental well-being through effective and accessible treatment options.
DopaGE is a developer of an overdose prevention education platform aimed at academic institutions, focusing on teaching students how to prevent, recognize, and respond to overdoses. With overdose being a leading cause of death among Generation Z and Millennial Americans, DopaGE offers a cloud-based course that is easy for institutions to implement. The platform features virtual, gamified educational content designed by emergency medical personnel and neuroscientists, which engages students and enhances their understanding of overdose response. By equipping students with life-saving knowledge and skills, DopaGE aims to make a significant impact on public health and safety in educational settings.
Journey Clinical is a platform that provides services to member psychotherapy practices that are independently owned and operated, and in no way owns, directs, or controls the mental healthcare clinicians providing care.
CB Therapeutics is a biotechnology company focused on the biosynthetic production of cannabinoids and tryptamines from sugar, utilizing a cellular agriculture platform. By employing yeast instead of traditional plant sources, the company produces pure cannabinoids, including CBD and THC, as well as psychedelic compounds and their analogs. This innovative approach aims to support clinical research for a range of serious health conditions, particularly in mental health, while promoting advancements in treatment options. CB Therapeutics seeks to enhance the healthcare industry’s capacity to address various diseases and improve overall healthspan.
Nucleus provides support for emerging companies within the psychedelic ecosystem. They deliver services to support the growing community of people helping people through psychedelic medicines.
Enthea is a company that facilitates access to safe and affordable psychedelic-assisted therapy as a workplace benefit. It enables businesses to offer coverage for essential mental health treatments through tailored workplace benefit plans. The company has established a trusted network of certified providers specializing in Ketamine-Assisted Therapy and other forms of Psychedelic-Assisted Therapy. By creating benefit plans for early adopter employers, Enthea aims to expedite health plan coverage for these therapies, promote the adoption of industry standards, and streamline reimbursement processes. This approach allows consumers to gain access to innovative mental health care options.
Spiritus Bioscience is a drug development company seeking to apply their proprietary drug-delivery technology to the Medicalized-Psilocybin market in Oregon
Psilera is a biopharmaceutical company dedicated to developing innovative therapeutics for neurodegenerative diseases and mental health disorders. The company focuses on creating a new class of neurological medicines, with its lead asset, PSIL-006, being a non-hallucinogenic psilocybin derivative aimed at treating frontotemporal dementia (FTD). Psilera's approach involves repurposing psychoactive natural products to develop next-generation therapies that enhance cognitive function and address mood and substance use disorders. Committed to scientific excellence, Psilera aims to transform the lives of individuals affected by these challenging conditions through its pioneering research and development efforts.
Beckley Retreats is a provider of virtual integration programs for healing. The company focuses on helping people with neurological and psychiatric disorders and offer training and certification for practitioners. Beckley Retreats offers a safe location, holistic training, dedicated care, and access to medical care.
Maya Health's mission is to improve psychedelic practitioners with the technology and data they need to scale safely and effectively, serve more people, and advance psychedelic healthcare. The company was founded in 2019 by David Champion and Akoni Anthony and is based in Denver, Colorado.
CB Therapeutics is a biotechnology company focused on the biosynthetic production of cannabinoids and tryptamines from sugar, utilizing a cellular agriculture platform. By employing yeast instead of traditional plant sources, the company produces pure cannabinoids, including CBD and THC, as well as psychedelic compounds and their analogs. This innovative approach aims to support clinical research for a range of serious health conditions, particularly in mental health, while promoting advancements in treatment options. CB Therapeutics seeks to enhance the healthcare industry’s capacity to address various diseases and improve overall healthspan.
Sempera Organics operates a vertically integrated, zero-waste lab farm focused on producing high-quality certified organic mushroom ingredients. The company specializes in a variety of products, including pure mushroom powders, proprietary blends, and extracts, which are available in bulk quantities. Sempera Organics emphasizes environmentally friendly cultivation methods, ensuring a reliable and sustainable approach to mushroom production. Its offerings cater to the functional foods, nutraceuticals, and cosmeceuticals industries, providing clinically validated mushroom ingredients that can be used in both wet and dry applications. The streamlined purchasing process enhances accessibility for consumers, aligning with the company's commitment to quality and sustainability.
Freedom Biosciences is a biotechnology platform focused on developing next-generation psychedelic therapeutics. The company aims to create innovative psychedelic pharmaceuticals by utilizing the established pharmacology of ketamine and other psychedelic compounds. This approach is intended to equip medical professionals with effective treatment options for patients suffering from resistant depression and various mental disorders.
Journey Clinical is a platform that provides services to member psychotherapy practices that are independently owned and operated, and in no way owns, directs, or controls the mental healthcare clinicians providing care.
Heading Health is a technology-enabled mental health platform focused on enhancing access to affordable mental health care. The platform provides personalized treatment solutions that utilize evidence-based therapeutics and innovative technologies, including Spravato, transcranial magnetic stimulation, telepsychiatry, and intramuscular ketamine. By offering these services, Heading Health aims to enable patients to experience meaningful improvements in their mental well-being through effective and accessible treatment options.
Multiverse is a digital marketplace that specializes in functional mushrooms, offering a variety of products including superfoods, snacks, supplements, and accessories. The company aims to promote the use of these mushrooms as health-enhancing items while fostering collaboration within the psychedelics industry. Through its innovative approach, Multiverse seeks to make functional mushrooms appealing to a broader audience, positioning itself as a leader in this emerging market. In addition to its core offerings, Multiverse also features SuperMush, which focuses on health supplements and streetwear inspired by the benefits of functional mushrooms.
Heading Health is a technology-enabled mental health platform focused on enhancing access to affordable mental health care. The platform provides personalized treatment solutions that utilize evidence-based therapeutics and innovative technologies, including Spravato, transcranial magnetic stimulation, telepsychiatry, and intramuscular ketamine. By offering these services, Heading Health aims to enable patients to experience meaningful improvements in their mental well-being through effective and accessible treatment options.
Adamo Bioscience focuses on developing innovative pharmaceutical treatments, particularly for Hypoactive Sexual Desire Disorder (HSDD). The company is engaged in researching psychedelic compounds and technology solutions, aiming to create products and services that enhance love and improve interpersonal relationships. By addressing issues related to sexual trauma, Adamo Bioscience seeks to empower clients to strengthen their connections and promote healing in their relationships.
Psychedelic Water is a pioneering brand in the legal psychedelic beverage market, focusing on creating non-alcoholic drinks designed to enhance mood and promote relaxation. The company offers a unique blend of ingredients, including kava root, damiana leaf, and green tea leaf extract, which together provide an uplifting experience without the drawbacks of traditional alcoholic beverages. These drinks aim to deliver a euphoric and clear-headed state, making them suitable for both recreational and professional settings. By championing the benefits of psychedelics, Psychedelic Water seeks to change perceptions and encourage the responsible enjoyment of their products.
MAPS is a 501(c)(3) non-profit research and educational organization that develops medical, legal, and cultural contexts for people to benefit from the careful uses of psychedelics and marijuana. The organization is focused on developing psychedelics and marijuana into prescription medicines, training therapists and working to establish a network of treatment centers, supporting scientific research into spirituality, creativity, and neuroscience, and educating the public honestly about the risks and benefits of psychedelics and marijuana. MAPS was founded in 1986 by Rick Doblin and is headquartered in Santa Cruz, California.
Driving Innovation at the Intersection of VR, Data, and Mental Health
The Breathwrk app offers easy to follow and highly effective guided breathing exercises that alleviate anxiety, promote sleep, increase energy, improve mood, help with athletic performance, and more!
Lykos Therapeutics aims to transform the approach to mental health by developing innovative medicines and therapeutic methods to address mental health disorders. With over thirty years of experience in researching psychedelic-assisted therapies, the company focuses on the integration of these treatments into the healthcare system. Lykos Therapeutics is dedicated to rigorous scientific standards, working to create and deliver new treatment options that facilitate healing and personal growth for individuals facing mental health challenges.
About Us: We have a passion to create virtual experiences that make a positive difference in physical health, mental well-being, education, and research. Our product development team is comprised of successful video game veterans. The FireflyVR team combines our extensive experience and science-focused development to build innovative new technologies with health and technology partners. We are honored to collaborate with some of the biggest innovators in the healthcare industry. What We Do: Four in ten adults in the U.S. have reported symptoms of anxiety or depressive disorder during the COVID pandemic. This is just one of many alarming statistics as we face a global and unavoidable mental health crisis. FireflyVR is determined to build new and novel ways to blend technology and therapies to ease this trend. Product: The Sanctuary is a Virtual Reality experience built to prepare a patient for a transformational ketamine treatment. It incorporates established techniques used by leading experts to provide a safe, engaging, and comfortable experience to prepare for meaningful therapy. The Sanctuary is a clinically designed solution that combines cognitive behavioral therapy to help reduce pre-procedure anxiety and develop positive intentions when the medicine is administered, ultimately improving outcomes. The Sanctuary is built with modularity in mind as other dissociative medicines become approved and understood beyond ketamine. We’re working hard with our team of experts to build and scientifically validate The Sanctuary as ketamine treatment becomes readily available. The modular foundation of The Sanctuary allows us to quickly and effectively adapt the experience to target a vast range of indications and therapies. Our initial target to treat treatment resistant depression is only the beginning of a wide-ranging and impactful journey.
Wake Network, Inc. is a Toronto-based company that specializes in clinical research and the use of fungi and plant-based medicine to promote healing benefits for the mind and body. Established in June 2018, the company has developed a gold-standard regenerative feedback loop that enables it to conduct research and monitor clinical studies on an individualized basis. By integrating the expertise of wellness professionals and leveraging technology, Wake Network aims to advance the future of mental and holistic health through innovative therapeutic solutions.
HOLOS is a boutique wellness center that specializes in immersive body and mind programming, emphasizing plant medicine experiences. The center focuses on consciousness expansion and healthy living, offering retreats designed to facilitate transformation and healing. Drawing on modern neuroscience and indigenous wisdom, HOLOS provides an environment that supports guests in their personal growth journeys. Through its unique approach, the company aims to establish a new standard in wellness, integrating various practices to enhance overall well-being.
Psychedelic Water is a pioneering brand in the legal psychedelic beverage market, focusing on creating non-alcoholic drinks designed to enhance mood and promote relaxation. The company offers a unique blend of ingredients, including kava root, damiana leaf, and green tea leaf extract, which together provide an uplifting experience without the drawbacks of traditional alcoholic beverages. These drinks aim to deliver a euphoric and clear-headed state, making them suitable for both recreational and professional settings. By championing the benefits of psychedelics, Psychedelic Water seeks to change perceptions and encourage the responsible enjoyment of their products.
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