National Institutes of Health

National Institutes of Health is a biomedical research agency of the U.S. Department of Health and Human Services, based in Bethesda, Maryland. It is the primary U.S. government organization devoted to biomedical and health research, conducting science through the Intramural Research Program and funding external research through the Extramural Research Program. The NIH comprises 27 institutes and centers and supports about 1,200 principal investigators and more than 4,000 postdoctoral fellows across basic, translational, and clinical research. It has contributed to major advances such as vaccines and therapies and is dedicated to advancing knowledge and translating discoveries into improvements in public health. Established in 1887, NIH operates as a central hub for medical research in the United States.

Francis Collins

Director

Nick Langhals

Supervisory Program Director

Past deals in South Central US

Arkansas Children's Research Institute

Grant in 2025
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

University of Arkansas for Medical Sciences

Grant in 2025
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Arkansas Children's Research Institute

Grant in 2024
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Oklahoma Medical Research Foundation

Grant in 2024
The Oklahoma Medical Research Foundation (OMRF) is a non-profit biomedical research institute dedicated to understanding and treating various devastating illnesses, including Alzheimer's, heart disease, lupus, multiple sclerosis, and cancer. It operates a research facility, providing services and access to resources that facilitate drug discoveries and improve patient care.

Marker Therapeutics

Grant in 2024
Marker Therapeutics is a clinical-stage immuno-oncology company developing adoptive non-gene modified T cell therapies for treating hematologic malignancies. Its MultiTAA technology selectively expands non-engineered T cells to target and kill tumor cells expressing multiple tumor-associated antigens, preventing immune escape.

University of Arkansas for Medical Sciences

Grant in 2024
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Arkansas Children's Research Institute

Grant in 2024
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

VenoStent

Grant in 2024
VenoStent develops bioabsorbable smart polymer wraps for vascular surgeries. Its flagship product, SelfWrap, is a perivascular wrap designed to reduce failures at the vein-artery junction in dialysis patients by promoting outward vein growth and providing custom-fit mechanical support. The company's technology acts as an external stent, reducing surgery time, infection risk, and wound reopening while improving vein usability and durability.

Arkansas Children's Research Institute

Grant in 2024
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

University of Arkansas for Medical Sciences

Grant in 2024
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

University of Arkansas for Medical Sciences

Grant in 2024
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

University of Arkansas for Medical Sciences

Grant in 2023
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Base Pair Biotechnologies

Grant in 2023
Base Pair Biotechnologies, Inc. is a biotechnology company based in Pearland, Texas, specializing in the research, development, and discovery of aptamer affinity ligands. Established in 2012, the company offers custom aptamer development services and a catalog of ready-made aptamers. Its innovative platform incorporates novel libraries and proprietary methods for multiplexing the aptamer discovery process, allowing for efficient screening and validation. Base Pair Biotechnologies collaborates with academic, commercial, and government institutions to create advanced tools and technologies across various sectors, including diagnostics, therapeutics, animal testing, agriculture, and environmental testing. The company's expertise in aptamer research, which began in 2004, has positioned it as a leader in the field, enabling clients to obtain high-quality aptamers with reduced time and cost.

Tulane University

Grant in 2023
Tulane University is a private research university based in New Orleans, Louisiana. Founded in 1834, it offers undergraduate, graduate, and professional programs across liberal arts, science and engineering, architecture, business, law, social work, medicine, public health, and tropical medicine. The university is a member of the Association of American Universities and supports extensive research through centers such as the Newcomb College Institute, the Roger Thayer Stone Center for Latin American Studies, the Tulane/Xavier Center for Bioenvironmental Research, the Murphy Institute, the Payson Center for International Development, the Tulane Cancer Center, the Tulane Center for Gene Therapy, and related institutes. Carnegie Foundation assigns Tulane a very high level of research activity, placing it among a select group of universities nationwide.

University of Oklahoma - Health Sciences Center

Grant in 2023
University of Oklahoma Health Sciences Center, as a comprehensive academic health center, is to educate students, residents, and other trainees in professional and graduate programs to become Oklahoma’s future team of healthcare leaders, clinicians, researchers, and educators; to advance distinctive basic, translational, clinical, and population research; to innovate and commercialize discoveries; and to deliver exceptional patient care across the full breadth of adult, women’s, and children’s specialties.

University of Arkansas for Medical Sciences

Grant in 2023
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

University of Texas Health Science Center at San Antonio

Grant in 2023
The University of Texas Health Science Center at San Antonio serves San Antonio and the 50,000 square-mile area of South Texas. It extends to campuses in the metropolitan border communities of Laredo and the Rio Grande Valley. More than 3,000 students a year train in an environment that involves more than 100 affiliated hospitals, clinics and health care facilities in South Texas. The UT Health Science Center and its Cancer Therapy & Research Center hold diversity as a core value. In this context, they are mindful of all aspects of human differences, such as socioeconomic status, race, ethnicity, language, nationality, sex, gender identity, sexual orientation, religion, geography, disability and age. At the UT Health Science Center and CTRC, inclusion is a core element for successfully achieving diversity, as they strive to create a climate that fosters belonging, respect and value for all. As an equal employment opportunity and affirmative action employer, the UT Health Science Center and CTRC exercise these core values of diversity and inclusion by promoting and ensuring equal employment opportunity for all individuals without regard to race, color, religion, sex, national origin, age, sexual orientation, disability, or veteran status.

Marker Therapeutics

Grant in 2023
Marker Therapeutics is a clinical-stage immuno-oncology company developing adoptive non-gene modified T cell therapies for treating hematologic malignancies. Its MultiTAA technology selectively expands non-engineered T cells to target and kill tumor cells expressing multiple tumor-associated antigens, preventing immune escape.

The University of Texas MD Anderson Cancer Center

Grant in 2023
The University of Texas MD Anderson Cancer Center is a leading institution dedicated exclusively to cancer patient care, research, education, and prevention. Located in the Texas Medical Center in Houston, Texas, it was established as one of the original three comprehensive cancer centers under the National Cancer Act of 1971. MD Anderson serves as both a degree-granting academic institution and a specialized cancer treatment facility. It is affiliated with two prominent medical schools: The University of Texas Medical School at Houston and Baylor College of Medicine. Renowned for its exceptional cancer care, MD Anderson has consistently ranked among the top cancer hospitals in the United States, earning the No. 1 position in U.S. News & World Report's "Best Hospitals" survey for ten of the past twelve years. The center is widely recognized for its commitment to advancing cancer treatment and improving patient outcomes.

Rice University

Grant in 2023
Rice University, established in 1912, is a private comprehensive research university based in Houston, Texas. It offers personalized academic experiences across various disciplines and fosters an intellectually diverse environment.

Arkansas Children's Research Institute

Grant in 2023
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Oklahoma Medical Research Foundation

Grant in 2023
The Oklahoma Medical Research Foundation (OMRF) is a non-profit biomedical research institute dedicated to understanding and treating various devastating illnesses, including Alzheimer's, heart disease, lupus, multiple sclerosis, and cancer. It operates a research facility, providing services and access to resources that facilitate drug discoveries and improve patient care.

University of Arkansas for Medical Sciences

Grant in 2022
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Texas Biomedical Research Institute

Grant in 2022
Founded in 1941, Texas Biomedical Research Institute is a renowned scientific research organization based in San Antonio, Texas. It focuses on innovative and cutting-edge research to understand and combat chronic and infectious diseases.

Arkansas Children's Research Institute

Grant in 2022
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Oklahoma Medical Research Foundation

Grant in 2022
The Oklahoma Medical Research Foundation (OMRF) is a non-profit biomedical research institute dedicated to understanding and treating various devastating illnesses, including Alzheimer's, heart disease, lupus, multiple sclerosis, and cancer. It operates a research facility, providing services and access to resources that facilitate drug discoveries and improve patient care.

University of Arkansas for Medical Sciences

Grant in 2022
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

University of Texas Health Science Center at San Antonio

Grant in 2022
The University of Texas Health Science Center at San Antonio serves San Antonio and the 50,000 square-mile area of South Texas. It extends to campuses in the metropolitan border communities of Laredo and the Rio Grande Valley. More than 3,000 students a year train in an environment that involves more than 100 affiliated hospitals, clinics and health care facilities in South Texas. The UT Health Science Center and its Cancer Therapy & Research Center hold diversity as a core value. In this context, they are mindful of all aspects of human differences, such as socioeconomic status, race, ethnicity, language, nationality, sex, gender identity, sexual orientation, religion, geography, disability and age. At the UT Health Science Center and CTRC, inclusion is a core element for successfully achieving diversity, as they strive to create a climate that fosters belonging, respect and value for all. As an equal employment opportunity and affirmative action employer, the UT Health Science Center and CTRC exercise these core values of diversity and inclusion by promoting and ensuring equal employment opportunity for all individuals without regard to race, color, religion, sex, national origin, age, sexual orientation, disability, or veteran status.

Arkansas Children's Research Institute

Grant in 2021
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Arkansas Children's Research Institute

Grant in 2021
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Nanoscope Therapeutics

Grant in 2021
Nanoscope Therapeutics Inc. is a biotechnology company based in Bedford, Texas, focused on developing innovative gene therapies aimed at restoring vision for individuals affected by retinal degenerative diseases, such as retinitis pigmentosa and dry age-related macular degeneration. Established in 2017, the company specializes in light-sensitive molecules and employs light-assisted gene delivery techniques to enable targeted treatment that re-sensitizes the retina, allowing patients to perceive low light levels. By utilizing a unique optogenetic approach, Nanoscope Therapeutics aims to deliver a solution for vision loss in patients where no effective cure currently exists, thereby advancing the potential for vision restoration in millions of affected individuals.

BiVACOR

Grant in 2021
BiVACOR, Inc. is a Houston-based company founded in 2008 that specializes in designing and manufacturing advanced centrifugal heart pumps. The company develops an artificial heart-pumping device aimed at fully replacing the function of a failing heart. This innovative device features a compact, magnetically levitated rotor situated between opposing pump casings, utilizing rotary blood pump technology to deliver necessary cardiac output. By minimizing the risk of blood-cell damage and clotting, BiVACOR's technology offers patients a reliable substitute for natural blood pumping systems. With a team of skilled engineers, medical specialists, and business executives, BiVACOR has established a robust network for collaboration both in the United States and internationally, including an office in Brisbane, Australia.

Cassava Sciences

Grant in 2021
Cassava Sciences is a clinical-stage biopharmaceutical company focused on neuroscience, developing novel treatments and diagnostics for nervous system disorders, notably Alzheimer's disease.

University of Arkansas for Medical Sciences

Grant in 2020
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Solenic Medical

Grant in 2020
Founded in 2019, Solenic Medical specializes in the development of a non-invasive medical device that uses alternating magnetic fields to eradicate biofilm on metallic implants. Its technology aims to address complications arising from surgeries like knee and hip replacements, as well as trauma-related implants.

Cassava Sciences

Grant in 2020
Cassava Sciences is a clinical-stage biopharmaceutical company focused on neuroscience, developing novel treatments and diagnostics for nervous system disorders, notably Alzheimer's disease.

VenoStent

Grant in 2020
VenoStent develops bioabsorbable smart polymer wraps for vascular surgeries. Its flagship product, SelfWrap, is a perivascular wrap designed to reduce failures at the vein-artery junction in dialysis patients by promoting outward vein growth and providing custom-fit mechanical support. The company's technology acts as an external stent, reducing surgery time, infection risk, and wound reopening while improving vein usability and durability.

Tulane University School of Medicine

Grant in 2018
Tulane University School of Medicine, part of the prestigious Tulane University established in 1834 in New Orleans, is dedicated to advancing medical education and research. It offers a comprehensive range of programs including graduate medical education, undergraduate medical education, and a biomedical sciences graduate program. The school also provides continuing education services to support lifelong learning in the medical field. With a focus on innovation, the Tulane School of Medicine cultivates an environment where students and faculty are engaged in pioneering research and practices that contribute to the advancement of healthcare. The institution is committed to preparing its graduates for leadership roles in medicine and related disciplines.

AxoSim

Grant in 2018
AxoSim is a biomimetic neuroscience platform company that develops 3D human nerve tissue models to support drug discovery. Its NerveSim in vitro system uses Schwann cell myelination and human-relevant electrical and structural metrics to predict clinical neurotoxicity and facilitate translation to humans, while Nerve-on-a-Chip and BrainSim technologies model nerve and brain tissue, enabling testing for neurotoxicity and neurodegenerative disease. The company grows living human cells in a 3D environment to mimic nerve tissue and advance preclinical drug evaluation. AxoSim aims to shorten development timelines and improve the relevance of preclinical assessments by providing platforms that emulate human neural physiology in the lab. The company was founded in 2018 and is based in New Orleans, Louisiana.

AxoSim

Grant in 2018
AxoSim is a biomimetic neuroscience platform company that develops 3D human nerve tissue models to support drug discovery. Its NerveSim in vitro system uses Schwann cell myelination and human-relevant electrical and structural metrics to predict clinical neurotoxicity and facilitate translation to humans, while Nerve-on-a-Chip and BrainSim technologies model nerve and brain tissue, enabling testing for neurotoxicity and neurodegenerative disease. The company grows living human cells in a 3D environment to mimic nerve tissue and advance preclinical drug evaluation. AxoSim aims to shorten development timelines and improve the relevance of preclinical assessments by providing platforms that emulate human neural physiology in the lab. The company was founded in 2018 and is based in New Orleans, Louisiana.

Arkansas Children's Hospital

Grant in 2018
Arkansas Children’s Hospital is the only pediatric medical center in Arkansas and one of the largest in the United States serving children. The campus spans 29 city blocks and houses 370 beds, a staff of approximately 500 physicians, 80 residents in pediatrics and pediatric specialties and more than 4,400 employees. The private, nonprofit healthcare facility boasts an internationally renowned reputation for medical breakthroughs and intensive treatments, unique surgical procedures and forward-thinking medical research - all dedicated to fulfilling our mission of enhancing, sustaining and restoring children’s health and development. For three years in a row Arkansas Children’s Hospital has been ranked on FORTUNE 100 Best Companies to Work For® list, most recently at No. 75.

Oklahoma Medical Research Foundation

Grant in 2018
The Oklahoma Medical Research Foundation (OMRF) is a non-profit biomedical research institute dedicated to understanding and treating various devastating illnesses, including Alzheimer's, heart disease, lupus, multiple sclerosis, and cancer. It operates a research facility, providing services and access to resources that facilitate drug discoveries and improve patient care.

7 Hills Pharma

Grant in 2018
7 Hills Pharma is a clinical-stage biopharmaceutical company based in Houston, Texas. It focuses on developing innovative therapies to enhance the efficacy of immune checkpoint inhibitors, adoptive cell therapy, and cord blood transplant for treating solid tumors and orphan genetic diseases.

University of Arkansas for Medical Sciences

Grant in 2017
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

AxoSim

Grant in 2017
AxoSim is a biomimetic neuroscience platform company that develops 3D human nerve tissue models to support drug discovery. Its NerveSim in vitro system uses Schwann cell myelination and human-relevant electrical and structural metrics to predict clinical neurotoxicity and facilitate translation to humans, while Nerve-on-a-Chip and BrainSim technologies model nerve and brain tissue, enabling testing for neurotoxicity and neurodegenerative disease. The company grows living human cells in a 3D environment to mimic nerve tissue and advance preclinical drug evaluation. AxoSim aims to shorten development timelines and improve the relevance of preclinical assessments by providing platforms that emulate human neural physiology in the lab. The company was founded in 2018 and is based in New Orleans, Louisiana.

SFC Fluidics

Grant in 2017
Founded in 2003, SFC Fluidics develops miniaturized analytical and diagnostic platforms using microfluidic technologies. Its product portfolio includes high-performance components like microfluidic pumps and detector arrays, instrument subsystems for various applications, and portable diagnostic platforms for point-of-care diagnostics.

University of Arkansas for Medical Sciences

Grant in 2017
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

CerSci Therapeutics

Grant in 2017
CerSci Therapeutics Inc. is a Dallas, Texas-based biotechnology company focused on developing non-opioid alternatives for the treatment of acute post-operative and chronic neuropathic pain, including pain associated with diabetes and chemotherapy. Founded in 2015, the company is advancing its lead drug candidate, CT-044, which has received approval from the United States Food and Drug Administration to proceed with Phase I clinical trials. CT-044 is a small molecule designed to decompose radical species such as peroxynitrite and hydrogen peroxide, and it is intended to address both acute and chronic pain conditions. As of August 2020, CerSci Therapeutics operates as a subsidiary of ACADIA Pharmaceuticals Inc.

University of Texas Health Science Center at San Antonio

Grant in 2017
The University of Texas Health Science Center at San Antonio serves San Antonio and the 50,000 square-mile area of South Texas. It extends to campuses in the metropolitan border communities of Laredo and the Rio Grande Valley. More than 3,000 students a year train in an environment that involves more than 100 affiliated hospitals, clinics and health care facilities in South Texas. The UT Health Science Center and its Cancer Therapy & Research Center hold diversity as a core value. In this context, they are mindful of all aspects of human differences, such as socioeconomic status, race, ethnicity, language, nationality, sex, gender identity, sexual orientation, religion, geography, disability and age. At the UT Health Science Center and CTRC, inclusion is a core element for successfully achieving diversity, as they strive to create a climate that fosters belonging, respect and value for all. As an equal employment opportunity and affirmative action employer, the UT Health Science Center and CTRC exercise these core values of diversity and inclusion by promoting and ensuring equal employment opportunity for all individuals without regard to race, color, religion, sex, national origin, age, sexual orientation, disability, or veteran status.

CerSci Therapeutics

Grant in 2017
CerSci Therapeutics Inc. is a Dallas, Texas-based biotechnology company focused on developing non-opioid alternatives for the treatment of acute post-operative and chronic neuropathic pain, including pain associated with diabetes and chemotherapy. Founded in 2015, the company is advancing its lead drug candidate, CT-044, which has received approval from the United States Food and Drug Administration to proceed with Phase I clinical trials. CT-044 is a small molecule designed to decompose radical species such as peroxynitrite and hydrogen peroxide, and it is intended to address both acute and chronic pain conditions. As of August 2020, CerSci Therapeutics operates as a subsidiary of ACADIA Pharmaceuticals Inc.

Tulane University

Grant in 2016
Tulane University is a private research university based in New Orleans, Louisiana. Founded in 1834, it offers undergraduate, graduate, and professional programs across liberal arts, science and engineering, architecture, business, law, social work, medicine, public health, and tropical medicine. The university is a member of the Association of American Universities and supports extensive research through centers such as the Newcomb College Institute, the Roger Thayer Stone Center for Latin American Studies, the Tulane/Xavier Center for Bioenvironmental Research, the Murphy Institute, the Payson Center for International Development, the Tulane Cancer Center, the Tulane Center for Gene Therapy, and related institutes. Carnegie Foundation assigns Tulane a very high level of research activity, placing it among a select group of universities nationwide.

Pulmotect

Grant in 2016
Pulmotect, Inc. is a biopharmaceutical company based in Houston, Texas, specializing in the development of inhaled therapeutics aimed at preventing and treating respiratory infections, particularly in cancer patients with compromised immune systems. Founded in 2007, the company's innovative approach focuses on enhancing the innate immune system to provide rapid and effective protection against a wide range of pathogens, including bacterial pneumonia, influenza, and fungal pneumonia, as well as potential bioterror agents. Pulmotect’s lead product, PUL-042, is a clinical-stage inhaled therapeutic that delivers immediate immune response, offering broad-spectrum protection that lasts for several days. By boosting the body’s natural defenses, Pulmotect aims to significantly reduce morbidity and mortality in vulnerable patient populations at risk of severe respiratory diseases.

AxoSim

Grant in 2016
AxoSim is a biomimetic neuroscience platform company that develops 3D human nerve tissue models to support drug discovery. Its NerveSim in vitro system uses Schwann cell myelination and human-relevant electrical and structural metrics to predict clinical neurotoxicity and facilitate translation to humans, while Nerve-on-a-Chip and BrainSim technologies model nerve and brain tissue, enabling testing for neurotoxicity and neurodegenerative disease. The company grows living human cells in a 3D environment to mimic nerve tissue and advance preclinical drug evaluation. AxoSim aims to shorten development timelines and improve the relevance of preclinical assessments by providing platforms that emulate human neural physiology in the lab. The company was founded in 2018 and is based in New Orleans, Louisiana.

Cassava Sciences

Grant in 2015
Cassava Sciences is a clinical-stage biopharmaceutical company focused on neuroscience, developing novel treatments and diagnostics for nervous system disorders, notably Alzheimer's disease.

Oklahoma Medical Research Foundation

Grant in 2014
The Oklahoma Medical Research Foundation (OMRF) is a non-profit biomedical research institute dedicated to understanding and treating various devastating illnesses, including Alzheimer's, heart disease, lupus, multiple sclerosis, and cancer. It operates a research facility, providing services and access to resources that facilitate drug discoveries and improve patient care.

ZZ Biotech

Seed Round in 2014
ZZ Biotech develops biological treatments for ischemic stroke and other neurological disorders. Its flagship product is 3K3A-APC, a genetically engineered variant of activated protein C (APC), designed to reduce bleeding risks while preserving cell-protective and anti-inflammatory activities. The company, founded in 2006, is currently conducting Phase 2 clinical trials for its treatment.

AquaMost

Grant in 2011
AquaMost, Inc. is a Madison, Wisconsin-based company specializing in the development and manufacturing of chemical-free water treatment solutions. Founded in 2006, AquaMost's flagship product, the SX Reactor, integrates multiple bacteria-killing technologies, including onsite generation of chlorine and hydroxyl radicals combined with ultraviolet irradiation, achieving over 99% efficacy in eliminating bacteria. This innovative system is particularly tailored for the oil and gas industry, but its applications extend to various sectors including food and beverage, drinking water treatment, dairy, and other industrial uses. AquaMost also provides delivery, setup, and maintenance support for its systems, which have been deployed in regions such as Texas, Colorado, Utah, and Canada.

Molecular Templates

Grant in 2010
Molecular Templates, Inc. is a clinical-stage biopharmaceutical company based in Austin, Texas, dedicated to the discovery and development of biologic therapeutics aimed at treating cancer and other serious diseases. The company utilizes its proprietary engineered toxin body (ETB) platform to create therapies with unique mechanisms of action that differ from traditional antibody-drug conjugates. Its lead candidate, MT-3724, is currently undergoing Phase II clinical trials for relapsed and refractory diffuse large B-cell lymphoma and non-Hodgkin’s lymphoma. Additionally, Molecular Templates is developing other candidates, including MT-4019, which targets CD38, and has a partnership with Takeda Pharmaceutical Company to create CD38-targeted therapies for multiple myeloma. The company also collaborates with Vertex Pharmaceuticals to enhance the hematopoietic stem cell transplant process through novel conditioning regimens.
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