The National Science Foundation (NSF) is an independent federal agency established in 1950 and based in Alexandria, Virginia. It is dedicated to supporting research and education in science and engineering across a wide range of disciplines. The NSF provides significant non-dilutive funding, up to $1.5 million, to startups and small businesses through its America's Seed Fund initiative, which is part of the Small Business Innovation Research (SBIR) program mandated by Congress. With an operating budget of approximately $7.8 billion, the NSF is committed to advancing fundamental research and education, thus fostering innovation and technological development in the United States.
Eascra Biotech specializes in developing DNA-inspired, Janus base nanomaterials for targeted drug delivery. Their platform, based on three generations of DNA nanotubes, is designed to effectively penetrate and treat hard-to-reach tissues like articular cartilage, the central nervous system, and solid tumors. These nanomaterials can encapsulate and stabilize various therapeutic agents, including mRNA, siRNA, proteins, and gene-editing tools, at room temperature, enhancing their efficacy and reducing systemic exposure.
Auxilium Health
Grant in 2025
Auxilium Health is creating low-cost, smart biomaterials for difficult-to-heal wounds.
Novaurum Biosciences
Grant in 2025
Novaurum Biosciences specializes in the development of AuPEC, a cell-based encapsulation technology aimed at enhancing the performance of implanted medical devices. This innovative platform integrates microbiology and nanotechnology to create nano-biological coatings for orthopedic implants. By reducing infection rates and promoting tissue regeneration, Novaurum's technology enables medical professionals to improve patient outcomes significantly. The company's approach offers a novel solution for addressing common challenges associated with implantable devices, ultimately contributing to safer and more effective medical interventions.
University of Nebraska Omaha
Grant in 2025
Students looking to work in state-of-the-art computer science and engineering facilities should look no further than the University of Nebraska at Omaha. UNO is a leader Bioinformatics, Computer Science and Management Information Systems programs. But UNO is not merely a four-year state university focused on science. With approximately 200 academic programs, this school offers an intimate atmosphere in a thriving city with numerous employment options for future graduates. The University of Nebraska at Omaha implements the Four-Year Guarantee resolution, meaning that the university will design a curriculum dedicated to permitting students to graduate as quickly as possible. UNO has a non-refundable $45 application fee for all applicants. The admissions requirements are based on core course prerequisites and performance requirements. The performance requirements for UNO admissions are a rank in the upper half of your graduating high school class and an ACT score of 20 or higher. The core course requirements are similar to the core requirements of other four-year colleges. UNO offers several types of financial aid to ease the cost of tuition. Not only do they have federal and state programs, but the school also offers scholarships, work-study programs and loans.
Rubi Laboratories
Grant in 2024
Rubi Laboratories is a California-based company that specializes in the development of technology to manufacture carbon-negative textiles. The firm utilizes innovative sustainable solutions to convert carbon emissions into natural fibers, resulting in biodegradable textiles. Its technology directly synthesizes threads, providing a natural resource for the production of viscose that is carbon-negative, as well as being water-chemical, land-neutral, traceable, and environmentally friendly. Rubi Laboratories aims to address the environmental impact of textile manufacturing by offering a more sustainable alternative in the industry.
Amphix Bio
Grant in 2024
Amphix Bio is engaged in the development of advanced therapeutic materials aimed at regenerative medicine. The company specializes in creating nanofiber materials that replicate the structure and dynamic characteristics of human tissues. By integrating biological signals, these materials instruct cells to activate regenerative processes. Amphix Bio's innovations enable the development of therapies designed to repair a variety of tissues, including bone, cartilage, muscle, cardiovascular tissues, and the brain and spinal cord. The promising results observed in both preclinical and clinical trials highlight the potential of Amphix Bio's approach in transforming therapeutic applications in medicine.
Eradivir
Grant in 2024
Eradivir is a biotech company established in 2020 and based in West Lafayette, Indiana. The company focuses on developing a novel bispecific immunotherapy platform aimed at combating the virus responsible for COVID-19. Eradivir's approach involves creating non-immunological targeting agents that possess high specificity and avidity for a unique domain of the spike protein found on various coronaviruses. This innovation enables the effective elimination of both free viruses and virus-infected cells, even during advanced stages of infection, thereby empowering patients' immune systems to address viral challenges more efficiently.
Wake Forest Institute for Regenerative Medicine
Grant in 2024
The Wake Forest Institute for Regenerative Medicine (WFIRM) is a leader in translating scientific discovery into clinical therapies. Physicians and scientists at WFIRM were the first in the world to engineer laboratory-grown organs that were successfully implanted into humans. Today, this interdisciplinary team is working to engineer more than 30 different replacement tissues and organs and to develop healing cell therapies-all with the goal to cure, rather than merely treat, disease.
SMART Reproduction
Grant in 2024
SMART Reproduction is a USDA-inspected and approved small ruminant semen and embryo collection facility.
Nanopath
Grant in 2024
Nanopath Inc. is a molecular diagnostics company focused on enhancing women's health through rapid and precise testing. By utilizing advancements in bioengineering and nanotechnology, the company specializes in the sensitive detection of viral, bacterial, and fungal pathogens without relying on nucleic acid amplification techniques. This innovative approach allows for the delivery of granular and clinically actionable information, thereby improving traditional testing methodologies and enabling healthcare providers to make informed decisions more swiftly.
The Wistar Institute
Grant in 2024
The Wistar Institute is the first independent institution in the United States dedicated to medical research and training, recognized for its significant contributions to biomedical science. Originally established as an anatomical teaching museum, it has transformed into a leading center for basic biomedical research and was designated a National Cancer Institute Cancer Center in 1972. The institute specializes in research areas including immunology, infectious diseases, and vaccine development. Its groundbreaking discoveries have facilitated the creation of vaccines for diseases such as rabies, rubella, and rotavirus, as well as the identification of genes linked to various cancers, including breast, lung, and prostate cancer. Additionally, Wistar has played a crucial role in advancing monoclonal antibodies and other vital research technologies, fostering a collaborative environment aimed at addressing critical health challenges.
Amplified Sciences
Grant in 2024
Amplified Sciences LLC is a molecular diagnostics company focused on the early detection of debilitating diseases, particularly pancreatic cancer and kidney disease. Utilizing an ultra-sensitive molecular sensing technology licensed from Purdue University, the company’s platform can detect disease markers at the single molecule level, enabling accurate diagnosis from bodily fluids such as urine and saliva. This versatile technology is designed for scalability to point-of-care applications, allowing for effective disease screening with a favorable cost structure. Amplified Sciences has developed a working prototype and has published proof of concept data, positioning itself to meet significant unmet medical needs in diagnostics. Founded in 2016 and based in West Lafayette, Indiana, the company was previously known as Nutrabiotix.
MelliCell
Grant in 2024
MelliCell is focused on combating chronic diseases through innovative tissue engineering technology, specifically targeting fat cells as a source of therapeutic adipokines. Their platform enables the conversion of human stem cells into large, mature fat cells, which can be used to develop drug therapies aimed at reducing fat mass while preserving lean mass. This unique approach is designed to address conditions such as obesity, diabetes, aging, oncology, and inflammation. MelliCell's team has garnered recognition through awards and partnerships with leading biopharma companies, validating their technology. By advancing oral small molecules that shrink fat cells, MelliCell aims to enhance health outcomes and improve the quality of life for individuals affected by these diseases.
Theromics
Grant in 2024
Theromics Inc. is a biotechnology company focused on developing innovative cell therapies, particularly in the field of thermal ablation for cancer treatment. Founded in 2016 and based in West Bridgewater, Massachusetts, the company has created HeatSYNC Gel, a biopolymer thermal accelerant designed to enhance the effectiveness of microwave and radiofrequency ablation procedures. This gel improves the delivery and absorption of thermal energy in soft tissue and bone, optimizing the ablation zone's shape and volume. By increasing local tissue electrical conductivity, HeatSYNC Gel helps to prevent heat loss due to blood flow, allowing for more precise targeting of tumors and protecting surrounding healthy tissue. The gel can be administered through various methods, including syringe, laparoscope, and bronchoscope, and is intended to improve the overall efficacy of thermal ablation therapies while enabling personalized treatment approaches.
Wake Forest Institute for Regenerative Medicine
Grant in 2024
The Wake Forest Institute for Regenerative Medicine (WFIRM) is a leader in translating scientific discovery into clinical therapies. Physicians and scientists at WFIRM were the first in the world to engineer laboratory-grown organs that were successfully implanted into humans. Today, this interdisciplinary team is working to engineer more than 30 different replacement tissues and organs and to develop healing cell therapies-all with the goal to cure, rather than merely treat, disease.
New Jersey Institute of Technology
Grant in 2023
Serious research-based academics in Technology and the Engineering, Biological and Computer Sciences on a remodeled, state-of-the-art campus is what you will find at New Jersey Institute of Technology (NJIT) in Newark, New Jersey. Applied Physics, Biocomplexity, Biomedical Engineering, Civil Engineering, Mathematical Engineering and Medical Informatics Technology are some of the more than 70 undergraduate degrees offered at NJIT. There are also more than 15 graduate programs. Not only do nearly 100% of faculty hold doctorates, but they also work on pioneering research with students and with local businesses and organizations as well. Research areas include such fields as Biological Sciences, Biomedical Studies, Nanotechnologies and Wireless Communications. Opportunities for work abound for NJIT grads in great part because of the quality of student training and the reputation of the school. Also important are the internships, which the school arranges for students while they’re still studying. Classrooms and research centers aren’t the only place on the NJIT campus that employ the most current technologies. The renovated campus recreation areas, computer labs, and restaurants add to the contemporary look and feel of the NJIT experience. Since Newark is the largest city in New Jersey there are also many employment opportunities available in the area. With its restaurants and cultural activities, Newark also provides much in the way of recreation and culture. New York City is also only 20 minutes away, so there is even more to be found in the off-campus experience. Admission to NJIT is competitive and undergraduates who are accepted usually have high grades and test scores. Many eligible undergraduates receive some form of financial aid.
Avisi Technologies
Grant in 2023
Avisi Technologies Inc. is a company based in Philadelphia, Pennsylvania, that focuses on developing innovative solutions for glaucoma treatment. Founded in 2017, the company has created VisiPlate, a next-generation aqueous shunt that utilizes nanotechnology to provide a defense against blindness caused by glaucoma. This advanced technology aims to improve the effectiveness of glaucoma treatments and enhance patient outcomes.
CerFlux
Grant in 2023
CerFlux specializes in personalized medicine technology designed to enhance cancer treatment by matching patients with the most effective therapies for their specific tumors. The company's innovative tests identify the most efficient and effective treatment options for individual patients, allowing healthcare practitioners to distinguish optimal therapies from less effective ones. This approach aims to improve patient outcomes and quality of life while minimizing the time, pain, and costs associated with cancer treatment. By focusing on personalized treatment efficacy, CerFlux contributes to a more tailored and effective healthcare experience for those battling cancer.
Remedium Bio
Grant in 2023
Remedium Bio is a Boston-based gene therapy company dedicated to developing curative treatments for various debilitating conditions. The company employs a modular approach to research and development, utilizing established technologies in innovative ways to address well-understood disease mechanisms. By focusing on clinically validated molecules and targeted treatment strategies, Remedium Bio aims to create effective therapies for conditions within rheumatology, endocrinology, and neurology. Its pipeline includes promising gene therapy candidates designed to tackle a wide range of diseases, including immune and age-related disorders.
Harpe Bio
Grant in 2023
Harpe Bioherbicide Solutions is a Raleigh-based company that provides sustainable weed-management solutions for organic and industrial agriculture. Harpe Bio's technologies deliver natural crop protection by utilizing a variety of plant extracts. The plant extracts serve as a platform that may be tailored to various weed management circumstances. Harpe's herbicide platform can be used alone or in conjunction with any currently marketed herbicide. Harpe's new modes and areas of action will improve synthetic herbicide efficacy, including the reduction of resistant weed populations.
Pheronym
Grant in 2023
Pheronym, Inc. is an agricultural biotechnology company based in Gainesville, Florida, focused on developing environmentally friendly solutions for pest control. Founded in 2011, the company offers a pheromone spray that enhances the efficacy of nematodes, which are microscopic roundworms used as organic insecticides. This innovative approach allows farmers to combat pests effectively, rivaling chemical pesticides while eliminating harmful health and environmental impacts. Pheronym also provides an additive that activates entomopathogenic nematodes (EPNs) and utilizes the nematodes' pheromones to influence their behavior and development. By leveraging synthetic biology, Pheronym aims to support farmers in transitioning from conventional pesticides to sustainable bio-pesticides, ensuring the health and freshness of crops.
Nexilico
Grant in 2023
Nexilico, Inc. is an early-stage biotechnology company based in Albany, California, specializing in precision medicine and microbiome research and development. Founded in 2017, the company focuses on creating advanced predictive computational platforms to enhance drug design and development processes. By pioneering next-generation in silico microbiome technologies, Nexilico aims to deepen the scientific understanding of microbiomes and their impact on health and disease. This knowledge is leveraged to create innovative microbiome-based solutions that improve therapeutic outcomes for various medical treatments.
GENASSIST
Grant in 2023
GENASSIST is a genetics company that provides assisted reproductive technology genetic consultation and testing services.
OmniVis
Grant in 2022
OmniVis is a biotechnology company that has created an integrated portable platform for the detection of pathogens in various environments, including food processing facilities. The company offers a handheld device that quantitatively measures pathogens, providing accurate results in under 30 minutes. This technology utilizes single-use disposable test kits that analyze swabs or liquid samples, significantly reducing the time and labor associated with traditional lab testing. By delivering a low-cost and user-friendly solution, OmniVis enables health organizations to enhance their pathogen detection capabilities effectively.
Atom Bioworks
Grant in 2022
Atom Bioworks focuses on developing a pattern-recognition enabled platform that combines DNA, antibody mimics, and advanced computational techniques for the detection and treatment of infectious diseases and cancer. The platform utilizes computational biology, quantum chemistry, software, and machine learning to identify specific surface protein patterns associated with diseases. By creating corresponding pattern-matching constructs, Atom Bioworks aims to enhance researchers' capabilities in early diagnosis and therapeutic interventions, ultimately improving medical applications in the fight against infectious diseases and cancer.
Protabit
Grant in 2022
Protabit specializes in protein engineering for various sectors, including industrial, agricultural, and healthcare applications. The company employs a unique platform technology that integrates computational modeling with high-throughput screening and directed evolution to enhance the diversity of protein sequences. This innovative approach allows Protabit to produce novel proteins tailored to specific needs. The development of their technology is supported by strategic partnerships with notable organizations, including Monsanto Company and the California Institute of Technology. Through its advanced methodologies, Protabit aims to advance the field of protein design and provide customized solutions for its clients.
Bespoke Biotherapeutics
Grant in 2022
Bespoke Biotherapeutics provides an effective natural immune response and overcomes the limitations of currently approved immunotherapies against cancer by inventing novel, customised living drugs called engineered B-cell therapeutics. They offer customised B-cell sourcing, isolation, activation, culture expansion, and non-viral genetic engineering methodologies uniquely suited to optimise commercial B-cell products for infusion.
BioSuperior Technology
Grant in 2022
BioSuperior Technology is a preclinical biotherapeutics company specializing in lung disease treatments. It has developed a novel, synthetic pulmonary surfactant prototype called BioSurf, which directly treats lung conditions and delivers potent drugs to restore normal lung function. This technology has the potential to repair damaged lung tissue and may also treat other microvasculature-related illnesses like hemorrhagic stroke and chronic kidney disease.
The Tiny Cargo
Grant in 2022
Tiny Cargo specializes in a unique drug delivery system utilizing non-immunogenic bovine milk-derived exosomes. This innovative approach allows for the effective oral or intravenous administration of potent therapeutics. The company focuses on delivering treatments for various serious health conditions, including ischemic heart disease, gastrointestinal radiation disease, and glioblastoma multiforme, among others. By leveraging its technology, Tiny Cargo aims to enhance the delivery of peptide drugs, making it applicable to a wide range of current peptide therapeutics and improving patient outcomes in the treatment of neurological and other pathologies.
OncoSTING
Grant in 2022
OncoSTING LLC, founded in 2018 and based in Baltimore, Maryland, specializes in developing innovative therapies for bladder cancer. The company's approach integrates the established efficacy of BCG immunotherapy with a novel delivery system for potent STING agonists, which aims to enhance treatment effectiveness while minimizing the adverse effects typically associated with traditional BCG therapy. By focusing on this combination, OncoSTING seeks to provide a more effective and safer treatment option for patients suffering from bladder cancer.
Brio
Grant in 2022
Brio provides strategic resourcing solutions to the biopharma, pharmaceutical, CRO, and medical device industries. They are skilled search experts with a passion for the science and art of recruiting, introducing only the best talent to preeminent companies.
NovoClade
Grant in 2022
NovoClade is a synthetic biology company focused on developing environmentally friendly insect control solutions. The company utilizes gene-editing technology to create sterile mosquito populations, effectively targeting the transmission of diseases associated with these insects. By emphasizing chemical-free methods, NovoClade aims to provide innovative pest control options that mitigate the impact of invasive species while ensuring minimal harm to the environment. Their approach offers clients the opportunity to implement effective strategies for controlling mosquito populations and addressing public health concerns related to insect-borne diseases.
Oculogenex
Grant in 2022
Oculogenex is a biopharmaceutical company based in La Habra, California, established in 2020. The company specializes in developing gene therapies specifically aimed at treating retinal disorders. Its innovative approach involves ocular regenerative gene therapy that protects retinal pigment epithelial cells from oxidative stress-induced damage, which is a contributing factor to macular degeneration. By focusing on these therapies, Oculogenex aims to enhance the detection and treatment of various retinal disorders, ultimately supporting researchers in advancing novel drug solutions in this critical area of healthcare.
Qualia Oto
Grant in 2022
Qualia Oto is a biomedical device company established in 2017 in Dallas, Texas, specializing in advanced cochlear implant technology aimed at improving the lives of individuals with hearing impairments. The company focuses on developing innovative devices that incorporate shape-changing polymers and matrix-addressed electrode arrays, which facilitate higher channel counts in cochlear implants and auditory brainstem implants. This technology allows for more precise stimulation of the auditory nerve, potentially leading to enhanced hearing capabilities. Qualia Oto's commitment to integrating machine learning into its stimulation techniques further aims to refine auditory experiences for users, addressing both medical and personal hearing needs.
Oxalo Therapeutics
Grant in 2022
Oxalo Therapeutics is focused on developing innovative drug therapies aimed at treating rare kidney diseases and preventing recurring kidney stones. The company specifically targets primary hyperoxaluria and other oxalate-related pathologies through a novel approach that utilizes a gut bacterium to facilitate the safe removal of oxalate from the body. By mimicking natural mechanisms, Oxalo Therapeutics seeks to provide effective treatment options for patients suffering from conditions associated with high levels of oxalate, thereby improving their quality of life and reducing the incidence of kidney stone recurrence. The company's expertise in the microbiome and translational research underpins its commitment to advancing early-stage technology in the field of kidney health.
Aqua Science
Grant in 2022
Aqua Science offers a global platform of technologies and fast and reliable solutions for the testing and treatment of water. They provide research and development, custom reagent and kit manufacture, product assembly, lyophilization services, and contract manufacturing services.
Uniphage
Grant in 2022
Uniphage is a biotechnology company that specializes in developing innovative solutions to combat bacterial infections, with a focus on agriculture. It combines the power of bacteriophages, naturally occurring viruses that infect bacteria, with artificial intelligence to create precise and safe antimicrobial products. Uniphage's primary goal is to reduce the use of harmful fungicides, bactericides, and antibiotics in plant agriculture by providing more efficient and eco-friendly alternatives. By using AI algorithms to predict the effectiveness of bacteriophages against specific bacterial infections, Uniphage aims to accelerate the development of new pesticides, thereby minimizing risks to human health and the environment.
Creative BioTherapeutics
Grant in 2022
Creative BioTherapeutics is a biotechnology company dedicated to developing innovative therapies for cancer and viral diseases. The company aims to transform cancer and viral disease research by targeting the fundamental issues of immune evasion and drug resistance. With a focus on recurrent and drug-resistant cancers, Creative BioTherapeutics is creating first-in-class biologics designed to address critical needs in treatment, particularly for patients with recurrent metastatic breast cancer. This approach not only seeks to enhance tumor regression but also holds the potential for cures in both adult and childhood cancers, thereby improving treatment options for patients facing these challenging conditions.
Simmbion
Grant in 2022
Simmbion specializes in innovative therapeutic solutions by utilizing symbionts to manufacture therapeutic agents directly within the human body, effectively transforming it into a living pharmacy. This technology aims to eliminate the challenges associated with traditional therapy manufacturing, such as the need for complex production processes, repeated injections, and temperature-sensitive storage. By providing a single injection that lasts up to 12 weeks, Simmbion's approach addresses supply chain disruptions and enhances affordability and accessibility of cell therapies for diverse patient populations. Their adaptable and universally immune compatible systems focus on delivering biological drugs directly in vivo, supporting a patient-centric and outcome-driven healthcare model while minimizing the risks of infections and immune rejection.
ViQi
Grant in 2022
ViQi offers software-as-a-service solutions for scientific image analysis, catering to various sectors including life sciences, construction, and agriculture. The platform enables users to customize services for data storage and analysis through a straightforward subscription model. ViQi specializes in custom image processing and informatics, providing tools such as bio-image semantic queries, module development, and assistance with intranet deployment. This allows clients to efficiently view, investigate, share, and store complex data and images, facilitating swift results and discoveries in their respective fields.
Ezrabio
Grant in 2022
Ezrabio is a biotechnology company that specializes in RNA adenylation technology, facilitating ribosome profiling across diverse biological samples. By offering rapid cDNA library construction and streamlined services from sample preparation to deep sequencing, Ezrabio empowers researchers and medical professionals to uncover hidden coding potential, analyze translational responses, identify tumor-associated antigens, and inform mRNA therapeutics. Their innovative approach simplifies complex processes, making it easier for scientists to conduct critical research in genetics and molecular biology.
Birch Biosciences
Grant in 2022
Birch Biosciences focuses on developing a proprietary platform that engineers enzymes for an innovative and sustainable plastic recycling process. By utilizing artificial intelligence, bioinformatics, and high-throughput screening techniques, the company creates enzymes that naturally and efficiently break down plastics. This method stands out from traditional recycling by producing virgin-quality, environmentally sustainable, and cost-competitive recycled materials, thereby contributing to a circular plastics economy. Birch Biosciences aims to provide businesses with an effective solution for addressing plastic waste while ensuring economic viability.
Phaxtec
Grant in 2022
Phaxtec specializes in developing and supplying eco-friendly material solutions, primarily focusing on the foodservice packaging, agriculture, and personal care sectors. The company's key product is polyhydroxyalkanoate (PHA) biopolymers, which are not only recyclable but also biodegradable in various environments, including soil, freshwater, and marine settings. This makes Phaxtec's offerings an attractive alternative for businesses seeking to reduce their environmental impact and transition towards more sustainable practices.
Canomiks
Grant in 2022
Canomiks operates a genomics and artificial intelligence-based technology platform that focuses on testing and certifying the biological efficacy and safety of ingredients and formulations. Its services cater to the functional food and beverage, dietary supplement, and skincare industries, allowing companies to develop safe and effective products efficiently. By leveraging omics science, data analytics, machine learning, and bioinformatics, Canomiks streamlines the validation process for product efficacy, ultimately enabling clients to enhance product quality while reducing development time and costs. The company's long-term vision is to actualize the concept of food as medicine.
Cryptyx Bioscience
Grant in 2022
Cryptyx Bioscience is a biopharmaceutical company focused on discovering new therapeutic natural products from bacteria without the use of genetics or cloning. Their innovative platform aims to activate silent biosynthetic gene clusters within bacteria, allowing them to unlock the full potential of culturable microbes. By employing a bioactivity-first approach, Cryptyx seeks to rapidly identify new antibiotics and antiviral drugs, addressing critical needs in combating infectious diseases prioritized by health organizations. The company's technology is designed to provide a broad range of medical services and therapeutic applications, ultimately enhancing treatment options for patients.
Petl Fluidics
Grant in 2022
PETL Fluidics operates a microfluidics platform designed for laboratory research. The company specializes in controlling, managing, and experimenting within microfluidic environments, facilitating a variety of applications such as chemical reactions, cell and organoid culture, advanced imaging, and mechanobiology. By providing custom-designed microfluidic solutions, PETL Fluidics aims to enhance the capabilities of laboratories engaged in cutting-edge scientific research.
Iaso Therapeutics
Grant in 2022
Iaso Therapeutics, founded in 2018 and based in East Lansing, Michigan, is a biotechnology company focused on developing vaccines aimed at improving human health and treating infectious diseases. The company’s platform is dedicated to creating vaccines for serious illnesses, including smallpox, yellow fever, and tetanus. By providing healthcare professionals with innovative technologies, Iaso Therapeutics seeks to enhance public health outcomes and address critical health challenges.
Secure Food Solutions
Grant in 2022
Secure Food Solutions, Inc. is a food safety company based in Martin, Tennessee, established in 2014. The company specializes in developing advanced technologies for the rapid detection of toxins, pathogens, and other contaminants in the global food supply. Among its notable innovations is a patented hyperspectral imaging technology specifically designed to identify corn contaminated with aflatoxin. Additionally, Secure Food Solutions offers rapid microbial tests that monitor and enumerate dangerous pathogens throughout the food and water supply chains. These diagnostic tools enable clients to enhance their food safety programs and mitigate the public health risks associated with foodborne illnesses and outbreaks, all while maintaining affordability.
NanoResearch
Grant in 2022
NanoResearch specializes in research, design, development, and commercialization of advanced technologies, particularly in the areas of energy storage, smart materials, mechanical smart lighting, and nanobiomedical products. The company serves a diverse clientele, including governments, businesses, and non-profit organizations, by providing innovative solutions that facilitate rapid market entry for technology organizations. Through its nanotech research and development platform, NanoResearch focuses on creating breakthrough technologies, particularly in battery solutions and smart materials, thereby addressing critical needs in energy management and biomedical applications.
Botany AI
Grant in 2022
Ummino offers precision fermentation technology for fortified food and beverage products. The company's technology unlocks rare compounds to transform commodity ingredients into high-value functional foods.
Lura Health
Grant in 2022
Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.
PureBiomass
Grant in 2022
PureBiomass specializes in sustainable algae cultivation systems and related services. The company offers a photo-bioreactor system designed for efficient algae production, featuring a metal support cage, a plastic bladder for culture volume, and a sterile apparatus for continuous harvesting. This system includes controls for pH and temperature, allowing production facilities to minimize water consumption and reduce their carbon footprint. In addition to algae cultivation, PureBiomass provides services for wastewater remediation, live feeds for shellfish, omega-3 production, and sustainable fish farming, contributing to environmentally friendly practices in aquaculture and resource management.
Visicell Medical
Grant in 2022
Visicell Medical is a company focused on developing innovative medical imaging technology that enhances the early detection and diagnosis of diseases. It specializes in creating safe and biodegradable stem cell tracking tools, which facilitate real-time monitoring of stem cells implanted in patients. These tools are designed for use in both clinical and pre-clinical settings, allowing healthcare professionals to track stem cell progress effectively. In addition to stem cell tracking, Visicell Medical offers specialized image capture systems and analysis tools that provide high-resolution, three-dimensional views of tissues and cells. This technology aids in the identification of abnormalities, enabling earlier intervention and improved treatment outcomes for patients, while also aiming to reduce overall healthcare costs.
Cytocybernetics
Grant in 2022
Cytocybernetics is a biotechnology company that specializes in cellular electrophysiology. The company has developed the Cybercyte, a user-friendly plug-and-play dynamic clamp system designed for ease of use in research settings. In addition to its innovative products, Cytocybernetics offers a comprehensive range of contract research organization (CRO) services, which include FDA-mandated drug safety screening, custom electrophysiology, custom modeling, and custom analysis. These services are aimed at assisting clients in the development and evaluation of various cellular products, ensuring that they meet regulatory requirements and scientific standards.
Window Therapeutics
Grant in 2022
Window Therapeutics is focused on discovering and developing innovative therapeutics to meet significant unmet patient needs in cancer and other severe diseases. The company specializes in breakthrough cancer treatments designed to specifically target and penetrate diseased tissue while sparing healthy cells. Utilizing a bioinspired cylindrical design, their therapies are engineered to home in on cancer sites, enhancing their effectiveness and addressing key challenges in cancer treatment. This targeted approach aims to accelerate drug development and reduce the risks associated with traditional therapies, ultimately improving outcomes for patients facing life-threatening conditions.
Acrigen Biosciences
Grant in 2022
Acrigen Biosciences focuses on enhancing the safety and efficacy of gene editing technologies, particularly those based on the CRISPR-Cas system. Founded in 2019 and headquartered in Berkeley, California, the company develops innovative solutions that aim to produce effective in vivo drug therapies to combat various diseases. Acrigen's proprietary technologies include Acro proteins that regulate the CRISPR-Cas gene editing process and an advanced bioinformatics discovery software platform that identifies suitable CRISPR systems for human therapeutic applications. Through these advancements, Acrigen Biosciences seeks to improve the precision, efficacy, and safety of genetic therapies, ultimately contributing to the potential prevention and cure of debilitating diseases.
Amphix Bio
Grant in 2022
Amphix Bio is engaged in the development of advanced therapeutic materials aimed at regenerative medicine. The company specializes in creating nanofiber materials that replicate the structure and dynamic characteristics of human tissues. By integrating biological signals, these materials instruct cells to activate regenerative processes. Amphix Bio's innovations enable the development of therapies designed to repair a variety of tissues, including bone, cartilage, muscle, cardiovascular tissues, and the brain and spinal cord. The promising results observed in both preclinical and clinical trials highlight the potential of Amphix Bio's approach in transforming therapeutic applications in medicine.
Stochastic Research Technologies
Grant in 2022
Stochastic Research Technologies specializes in delivering fundamental and applied research focused on algorithms, methods, and tools that address challenges in energy, environmental sustainability, molecular modeling, process management, supply chain management, and biomedical engineering. The company develops software solutions aimed at resolving complex issues in the chemical, pharmaceutical, and biomedical sectors. By leveraging modeling, optimization under uncertainty, and process control, Stochastic Research Technologies enables clients across various industries to access effective solutions tailored to their specific needs.
Renerva
Grant in 2022
Renerva is a growing medical device company that specializes in the development and commercialization of implantable technologies designed to enhance peripheral nerve repair procedures. The company's products aim to facilitate nerve repair, recovery, and storage, focusing on improving patient outcomes and accelerating healing processes. By providing innovative surgical devices, Renerva enables healthcare professionals to effectively assist patients in regaining function following nerve injuries.
UCHU Biosensors
Grant in 2022
UCHU Biosensors develops a platform of tooth mounted sensors to effortlessly track health through saliva.
WaveArray
Grant in 2022
WaveArray is a technology company based in Naples, Florida, founded in 2017. It specializes in developing an electronic platform aimed at eliminating biofouling, a common problem in marine environments. The company's innovative approach utilizes electronic technology and principles of water energy interaction to create microbubbles on submerged surfaces, which effectively inhibit the growth of hard-shelled organisms and algae. By preventing the formation of microorganisms on man-made surfaces, WaveArray offers a sustainable alternative to traditional antifouling paints and coatings, which can pose risks to marine ecosystems.
InvVax
Grant in 2022
InvVax, Inc. is a vaccine development company based in Los Angeles, California, founded in 2012. The company focuses on creating innovative vaccines, with its primary product being a universal influenza vaccine aimed at preventing pandemics. Utilizing a proprietary platform, InvVax's technology analyzes influenza proteins to address virus mutations, thereby enhancing the effectiveness of vaccines. In addition to its work on influenza, InvVax is exploring vaccine candidates for other viral infections, including HIV, Hepatitis B, and Hepatitis C.
Bactana
Grant in 2022
Bactana Corporation focuses on researching and developing nutritional products aimed at enhancing microbiome health in livestock and pets. The company has created a product platform called FPS-4, which leverages the beneficial interaction between an animal’s immune system and metabolism to boost productivity while ensuring good health. Bactana's approach includes identifying and isolating beneficial molecules from anaerobic bacteria found in the animal microbiome. The company also targets metabolic conditions and digestive disorders in pets, aiming to develop therapies for issues such as prediabetes and diabetes. Additionally, Bactana is committed to creating sustainable products that reduce the reliance on antibiotics and conserve natural resources in livestock production. Founded in 2016 and headquartered in Farmington, Connecticut, Bactana serves cattle farmers primarily in Connecticut and New York.
Isolere Bio
Grant in 2022
Isolere Bio is a biotechnology company dedicated to simplifying the purification of biotherapeutics, particularly monoclonal antibodies and Adeno-Associated Viruses (AAV). Co-founded with the aim of enhancing global access to essential drugs, Isolere Bio develops innovative manufacturing technologies that utilize a straightforward Tangential Flow Filtration (TFF) setup. This approach facilitates a seamless transition from laboratory-scale processes to large-scale industrial production, thereby improving efficiency within the bioprocessing industry. As monoclonal antibodies continue to gain prominence as effective therapeutics and important research tools, Isolere Bio's work plays a crucial role in advancing the development of new diagnostics and treatments.
Auctus Biologics
Grant in 2022
Auctus Biologics is a pre-clinical biotechnology company focused on developing antibody mimetics for therapeutic and diagnostic uses. By engineering a ribose-binding protein, the company aims to create a scaffold that binds clinical targets with an affinity comparable to monoclonal antibodies while addressing the limitations associated with traditional antibodies. These limitations include instability and the need for costly cold-chain logistics, which can hinder their effectiveness in extreme environments such as the gastrointestinal tract. Auctus Biologics' innovative approach allows for treatments that are not only more resilient, capable of withstanding conditions like repeated boiling cycles, but also more accessible and cost-effective for patients. This advancement may significantly enhance the delivery of advanced medical therapies.
OmicsCraft
Grant in 2022
OmicsCraft offers customers access to a customised data analytics pipeline and a sample-to-solution service. They offer cloud-based platforms that allow them to build analytics pipelines for omic data preprocessing, mass spectrometric-based metabolite identification, differential analysis of metabolite profiles, and multi-omics integration.
Pathotrak
Grant in 2022
Pathotrak, LLC, founded in 2016 and based in College Park, Maryland, develops innovative food safety testing kits that significantly enhance the detection of food-borne pathogens, such as Salmonella and E. coli. Utilizing advanced microfiltration technology, Pathotrak's kits reduce the testing time from 1-2 days to just 6 hours, streamlining the traditional 22-hour enrichment process. This rapid detection capability not only ensures compliance with FDA and USDA regulations but also integrates seamlessly into existing detection systems. By minimizing holding times and associated costs, as well as enabling quicker product releases, Pathotrak's technology aims to transform food safety practices and logistics in the industry, ultimately helping to prevent dangerous outbreaks and improve overall food safety.
Psyonic
Grant in 2022
Psyonic, Inc. specializes in developing advanced bionic limbs aimed at enhancing the lives of individuals with amputations. Founded in 2015 and headquartered in Champaign, Illinois, the company focuses on creating accessible, affordable solutions for its users. Its flagship product, an advanced bionic hand, is notable for its speed, ease of control, and ability to provide sensory feedback. The hand utilizes muscle pattern recognition and machine learning algorithms, allowing for customization based on the user's specific needs and preferences. Designed to withstand impacts, the bionic hand is intended to enable users to perform daily tasks with greater ease. Psyonic's goal is to ensure that the costs associated with its products are fully covered by insurance, minimizing out-of-pocket expenses for consumers.
Lepidext
Grant in 2021
Lepidext specializes in managing populations of Lepidoptera pests through the development of species-specific bio-pesticides. Founded in 2015 by Angelika Fath-Goodin and Bruce Webb in Lexington, Kentucky, the company aims to enhance crop security and promote agricultural prosperity. By leveraging a deep understanding of insect biology alongside farmers' expertise, Lepidext provides safe and effective pest control solutions that reduce reliance on genetically modified plants and chemical pesticides. Their technology specifically targets the corn earworm and other harmful insects, offering an innovative approach to pest management that is user-friendly and environmentally responsible.
PZA Innovation
Grant in 2021
PZA Innovation is a biotechnology company focused on developing a reliable testing method for pyrazinamide, a first-line drug used in tuberculosis treatment. The company employs reverse engineering techniques to determine the specific conditions under which pyrazinamide is effective in vitro, thereby enhancing its action against mycobacterium tuberculosis in a living host. By improving the understanding of pyrazinamide susceptibility, PZA Innovation aims to enable healthcare professionals to offer a next-generation treatment that could potentially shorten the duration of tuberculosis therapy for patients.
BiRed Imaging
Grant in 2021
Bired Imaging specializes in infrared imaging technology aimed at enhancing breast cancer detection and localization, particularly in patients with dense breast tissue. Their medical imaging platform employs thermography and a proprietary computerized detection algorithm, which allows for the accurate identification of tumor size and location. This innovative approach enables healthcare professionals to detect high-risk patients at earlier stages, improving screening efficacy while also being cost-effective. Bired Imaging's solutions serve as an important adjunctive technology in breast cancer screening, contributing to more precise diagnostic processes.
DNALite Therapeutics
Grant in 2021
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, DNALite utilizes innovative oral lipid nanoparticle technology to deliver mRNA and pDNA directly to intestinal stem cells. This approach targets the underlying causes of diseases such as Familial Adenomatous Polyposis, a hereditary form of colorectal cancer that often necessitates invasive surgeries in adolescents. By enabling the intestinal tract to secrete therapeutic proteins into the bloodstream, DNALite aims to transform conventional protein biologics into oral medications, potentially improving patient outcomes and accessibility to treatment.
MBF Therapeutics
Grant in 2021
MBF Therapeutics, Inc. is a veterinary oncology company that specializes in developing and commercializing innovative therapies for cancer treatment in dogs and cats. The company's product portfolio features targeted immunotherapies and small molecule drugs designed to disrupt tumor cell metabolism while sparing healthy tissues. Key products include MBFT-101, a combination therapy for sarcomas and lymphoma that utilizes a proprietary polyamine transport inhibitor alongside a potent inhibitor of ornithine decarboxylase, and MBFT-102, an immunotherapy based on the tumor suppressor/cytokine mda-7/IL24, which has shown promise in human clinical trials for various advanced cancers. Additionally, MBF Therapeutics is advancing a gene-based vaccine platform aimed at improving treatments for both cancer and infectious diseases in animals, with the potential to transform veterinary medicine. The company is located in Ambler, Pennsylvania, and maintains a strategic partnership with the Lankenau Institute for Medical Research.
Nanopath
Grant in 2021
Nanopath Inc. is a molecular diagnostics company focused on enhancing women's health through rapid and precise testing. By utilizing advancements in bioengineering and nanotechnology, the company specializes in the sensitive detection of viral, bacterial, and fungal pathogens without relying on nucleic acid amplification techniques. This innovative approach allows for the delivery of granular and clinically actionable information, thereby improving traditional testing methodologies and enabling healthcare providers to make informed decisions more swiftly.
Aqueduct Fluidics
Grant in 2021
Aqueduct Fluidics, founded in 2019 and headquartered in Philadelphia, PA, specializes in developing automation solutions tailored for physical and life sciences research on laboratory benchtops. The company offers a software automation tool designed to streamline workflows and enhance the integration of hardware components. Its platform enables users to write automation scripts and provides an intuitive interface for controlling and visualizing hardware status. By simplifying system integration and addressing complex elements such as communication protocols, command timing, user interfaces, and data management, Aqueduct Fluidics equips developers with the necessary tools and resources to efficiently create, test, and deploy automation programs for benchtop-scale applications.
Atom
Grant in 2021
Atom Limbs is focused on advancing the field of prosthetics with its innovative mind-controlled artificial arms, specifically designed for under-elbow amputees and individuals with quadriplegia. The company’s flagship product, the Atom Touch, allows users to regain mobility by interpreting brain signals through implanted electrodes, facilitating natural and intuitive movement of the prosthetic limb. This technology is rooted in research and development conducted at the Johns Hopkins University Applied Physics Laboratory and has received substantial funding from DARPA. Atom Limbs aims to enhance the quality of life for those with mobility challenges by providing advanced, customizable solutions for artificial limbs.
Rubi Laboratories
Grant in 2021
Rubi Laboratories is a California-based company that specializes in the development of technology to manufacture carbon-negative textiles. The firm utilizes innovative sustainable solutions to convert carbon emissions into natural fibers, resulting in biodegradable textiles. Its technology directly synthesizes threads, providing a natural resource for the production of viscose that is carbon-negative, as well as being water-chemical, land-neutral, traceable, and environmentally friendly. Rubi Laboratories aims to address the environmental impact of textile manufacturing by offering a more sustainable alternative in the industry.
Astek Diagnostics
Grant in 2021
Astek Diagnostics is focused on developing a precision diagnostic platform that assists physicians in prescribing appropriate antibiotics for patients suffering from bacterial sepsis within one hour. The company’s technology utilizes a single-use cartridge to rapidly detect bacterial infections in urine by measuring the oxygen consumption of various bacterial species. This innovative approach not only speeds up the identification process but also aids in combating antibiotic resistance through effective susceptibility testing.
Vulcan Biologics
Grant in 2021
Vulcan Biologics is a biotechnology company based in Irvine, California, established in 2019. It specializes in the modulation of the microbiome through the use of bacteriophages, which are viruses that specifically infect bacteria without harming human cells. This innovative platform aims to achieve stable and persistent changes in the gut microbiome, facilitating the treatment of gluten-related disorders such as gluten sensitivity and celiac disease. By altering the composition of gut bacteria, Vulcan Biologics enables healthcare providers to offer targeted therapeutic solutions for individuals affected by these conditions.
Akttyva Therapeutics
Grant in 2021
Akttyva Therapeutics specializes in the development of targeted therapeutics aimed at addressing cell barrier dysfunction associated with various vascular disorders. The company leverages a deep understanding of biological pathways, along with advanced artificial intelligence and machine learning techniques, to design solutions that enhance the treatment of these conditions. Through its innovative approach, Akttyva Therapeutics seeks to provide healthcare professionals with effective tools to manage and treat disorders related to cell barriers.
Corinnova
Grant in 2021
CorInnova Incorporated, founded in 2004 and based in Houston, Texas, specializes in device-based therapies aimed at treating congestive heart failure. The company is known for its innovative non-blood-contacting soft robotic cardiac assist device, which has the potential to significantly increase the number of heart failure patients eligible for life-saving device therapies. By focusing on advanced technological solutions, CorInnova seeks to improve outcomes for individuals suffering from this serious condition.
Cision Vision
Grant in 2021
Cision Vision is a developer and supplier of advanced imaging medical products focused on enhancing the examination of lymph nodes. Their innovative technology allows pathologists to visualize, scan, and record lymph nodes in real time with high contrast, without the need for injections or radiation. This capability supports the modernization of pathology practices, ensuring consistency and high-quality care in medical diagnostics. By providing these biotechnology tools, Cision Vision aims to improve the efficiency and accuracy of lymph node assessments in clinical settings.
Uncaged Innovations
Grant in 2021
Uncaged Innovations focuses on developing next-generation biomaterials that replicate bovine and exotic leather using advancements in materials chemistry and digital manufacturing. The company aims to provide sustainable and ethical alternatives to traditional animal skins, catering to various industries, including luxury fashion and automotive. By leveraging innovative technologies, Uncaged Innovations supports businesses seeking to adopt environmentally friendly practices while maintaining high-quality material standards.
Zymosense
Grant in 2021
Zymosense specializes in the development of an enzyme screening platform that utilizes innovative technology to identify and characterize enzymes with specific properties. The company offers automated aqueous two-phase extraction for the efficient sorting of chiral-pure single-walled carbon nanotubes, enhancing the scalability and cost-effectiveness of this process. Additionally, Zymosense has demonstrated the potential for automating the NIST-developed ATP system for the separation of these nanotubes. Their tools, including a plate reader and a handheld reader, leverage fluorescent nanoparticles suspended in target enzyme substrates to produce activity probes, ensuring accuracy while maintaining user-friendliness. This combination of technologies enables research scientists and biotechnology companies to rapidly evaluate, discover, and design new enzymes, thereby advancing various applications across multiple industries.
Insectapel
Grant in 2021
InsectaPel specializes in biobased insect repellent products designed for textiles, focusing on providing effective solutions to prevent blood-sucking insects from biting humans. The company’s innovative extended-release technology enhances the functionality of fabrics, ensuring long-lasting protection while adhering to regulatory standards. By offering sustainable and cost-effective alternatives, InsectaPel aims to transform the market for insect repellents, addressing both consumer needs and public health concerns related to insect-borne diseases.
Synvivia
Grant in 2021
Synvivia, Inc. is a biotechnology company founded in 2016 and based in Berkeley, California. It specializes in developing synthetic biology products, particularly ON-OFF switches for genetically engineered organisms. These protein switches can be controlled by small molecules, allowing for precise manipulation of biological functions. By integrating these switches into organisms, Synvivia aims to create engineered life forms that can be effectively used in healthcare. The company also focuses on generating biosensors that enhance enzymatic activities, facilitating easier disease diagnosis and enabling healthcare providers to deliver appropriate treatments.
Organic Robotics
Grant in 2021
Organic Robotics Corporation, founded in 2018 and based in Rochester, New York, specializes in the design and development of advanced sensors that measure touch in real time. The company's flagship product, Light Lace, utilizes fiber-optic technology to create a flexible sensor capable of bending and twisting with the human body, offering effective motion capture and pressure sensing. This innovative solution combines sensibility, elasticity, and washability at a competitive cost. Additionally, Organic Robotics focuses on performance monitoring for professional athletes, providing real-time feedback on motion, muscle fatigue, and vital signs. Their technology is designed for comfort and minimal distraction, enabling accurate analysis of chest movement to deliver actionable insights regarding fatigue and performance levels.
Spekciton Biosciences
Grant in 2021
Spekciton Biosciences specializes in biophotonic measurement systems and services aimed at enhancing agricultural performance and sustainability. The company develops innovative technologies that enable the rapid and precise detection of plant stress and viability, providing farmers with essential insights for improving crop management. Additionally, Spekciton offers biosensors designed to quickly identify soil and water contamination, supporting environmental health and agricultural productivity. Through its advanced measurement solutions, the company contributes to a better understanding of bioprocesses, ultimately aiding in the cultivation of resilient and sustainable crops.
Beyond The Dome
Grant in 2021
Beyond The Dome specializes in the destruction of organic compounds, focusing on challenging materials such as PFAS, microplastics, and pharmaceuticals. The company has developed small, efficient systems that offer significant throughput for waste management. Their supercritical water oxidation technology effectively processes biosolids, sludge, and various organic wastes, presenting an environmentally friendly solution for managing hazardous and chemically contaminated materials. Beyond The Dome aims to contribute to cleaner water and improved waste management practices through its innovative approach.
BioSapien
Grant in 2021
BioSapien is a pre-clinical biotechnology company focused on creating innovative biodegradable implantable products for oncology applications. The company is developing a 3D-printed drug delivery platform that utilizes a biodegradable mesh to deliver active pharmaceutical ingredients (APIs) directly to tumor sites, thereby minimizing systemic side effects associated with traditional therapies. Their flagship product, the MediChip, is designed to administer FDA-approved high-dose systemic therapies in a localized and sustained manner, enhancing the quality of patient care. Current research is focused on applications for pancreatic and lung cancers, with plans to expand the pipeline to include other types such as colorectal, breast, and stomach cancers. By targeting drug delivery directly to cancerous tissues, BioSapien aims to improve treatment efficacy while reducing toxicity for patients.
Huue
Grant in 2021
Huue is a company focused on providing sustainable dyeing solutions for the denim and textile industries, specifically through the use of bio-synthesized indigo dyes. By employing fermentation biotechnology, the company utilizes naturally occurring microorganisms to produce colors, which significantly reduces the reliance on toxic chemicals traditionally used in dye production. This innovative approach not only enhances the environmental sustainability of the denim supply chain but also offers a greener alternative for fashion and textile manufacturers seeking to create eco-friendly products. Huue's commitment to harnessing renewable resources positions it as a leader in the movement towards more sustainable practices in the industry.
Aracari Biosciences
Grant in 2021
Aracari Biosciences specializes in developing advanced 3D Vascularized Micro-Organ platforms aimed at improving the drug discovery process. These platforms enhance the biological authenticity of pre-clinical testing by allowing for real-time imaging of vessel morphology, which facilitates the investigation of lead compound efficacy against tumors in a three-dimensional environment. The technology is designed to adapt to various physiological conditions and can be perfused with fluorophore-tagged dextrans of different molecular weights. This capability assists pharmaceutical companies in making informed decisions and accelerates the development of new drugs.
Envivo Bio
Grant in 2021
Envivo Bio develops a non-invasive device that collects microbiome samples from all regions of the human gastrointestinal tract. The company is based in San Carlos, California.
Soil Culture Solutions
Grant in 2021
Soil Culture Solutions, LLC, founded in 2014 and headquartered in Tampa, Florida, specializes in innovative genetic alteration technology. The company focuses on developing citrus trees that utilize CRISPR editing techniques to enhance resistance to severe diseases affecting the citrus industry. Soil Culture Solutions holds exclusive licenses to patents from community universities, enabling it to employ precision breeding methods to combat these critical infections in citrus crops.
Felix Biotechnology
Grant in 2021
Felix Biotechnology, founded in 2019 and based in San Francisco, California, is focused on developing biotherapeutics aimed at addressing microbial challenges in human health, particularly antibiotic-resistant strains of bacteria and fungi. The company aims to accelerate the deployment of innovative treatments for infectious diseases, enabling healthcare professionals to manage these urgent health threats effectively. Through its targeted approach, Felix Biotechnology seeks to provide precise and effective solutions to combat the growing issue of antibiotic resistance.
AgroSpheres
Grant in 2021
AgroSpheres, LLC, founded in 2016 and based in Charlottesville, Virginia, specializes in innovative pesticide delivery technology aimed at improving crop protection products. The company develops engineered bio-particles that efficiently deliver pesticide-degrading enzymes, significantly reducing the waiting periods between pesticide application and harvest. By employing a unique encapsulation and delivery platform, AgroSpheres enhances the effectiveness of various crop protection solutions, including fungicides, insecticides, and herbicides. The firm focuses on creating biodegradable technologies that minimize harmful pesticide residues on plants, utilizing bioengineering and industrial fermentation techniques to produce biomolecules and chemicals that target toxic materials. This approach not only benefits agricultural businesses but also promotes the health and well-being of plants and their products.
Fortiphyte
Grant in 2021
Fortiphyte offers agricultural protection products that help to protect crops from disease and reduce fungicide use. The company was founded in 2017 and is based in Berkeley, California.
Biochip Labs
Grant in 2021
Biochip Labs, founded in 2019 and headquartered in Cleveland, Ohio, specializes in laboratory testing services for blood disorders, particularly sickle cell disease and thalassemia. The company offers a variety of proprietary microfluidic biomarker assays that assess blood cell adhesion, red blood cell deformability, whole blood rheology, and endothelialized microfluidics. These assays are designed to evaluate the efficacy of emerging targeted and curative therapies, allowing clinicians to effectively monitor patient responses to treatment. By focusing on accurate and high-quality testing, Biochip Labs aims to advance the understanding and management of blood disorders.
CollaMedix
Grant in 2021
CollaMedix specializes in the development of collagen-based medical devices aimed at addressing soft tissue repair and augmentation. The company focuses on treating stress urinary incontinence in women, a condition that results in urine leakage during activities such as laughing, coughing, sneezing, lifting, and exercising. CollaMedix utilizes proprietary collagen materials to create a bio-inductive scaffold, which is a strong fabric designed to support human tissue and facilitate rapid cell integration. This innovative approach allows researchers to explore new and effective treatments for female pelvic health, ensuring safety and efficacy in their medical solutions.
Beta Analytic
Grant in 2021
Beta Analytic is a company specializing in radiocarbon dating and isotope analysis, serving various scientific fields including geochronology and environmental studies. The firm provides a range of services that encompass stable isotope analysis, biobased and natural product testing, essential oil testing, and renewable carbon measurement. Additionally, it offers nitrate source tracking and biofuels renewable carbon testing. By utilizing advanced techniques such as accelerator mass spectrometry and isotope ratio mass spectrometry, Beta Analytic enables researchers to accurately measure natural levels of radiocarbon and stable isotope ratios, facilitating the study of carbon-based materials for diverse applications.
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