National Science Foundation

The National Science Foundation is an independent federal agency in the United States that funds and supports research and education in science and engineering. It funds fundamental research and education across all fields of science and engineering and administers non-dilutive funding programs to aid early‑stage technology development, helping translate discoveries into commercially viable products and services. Through grants and fellowships, the NSF supports researchers, educators, and startups, contributing to innovation and U.S. competitiveness. The agency operates with a substantial budget to advance science, engineering, and STEM education nationwide.

James Donlon

Program Director

Sean L. Jones

Assistant Director for Mathematical and Physical Sciences

Debasis Majumdar

Program Director

Graciela Narcho

Staff Associate

Sethuraman Panchanathan

Director

Past deals in Refrigeration

Desert Valley Tech

Grant in 2021
Founded in 2018, Desert Valley Tech specializes in developing advanced cold chain storage systems. These systems maintain precise temperatures for blood, pharmaceuticals, biologics, organs, and other sensitive items, optimizing power consumption and offering customizable modular storage solutions. This enables improved patient outcomes, particularly in challenging medical environments.

Nativus

Grant in 2020
Nativus is a hardware technology company developing a hyper-efficient air-conditioner for commercial and residential applications in the heating and cooling industry. Current technologies have remained stagnant for decades, receiving only incremental improvements over the past 50 years. However, through our patent-pending technology which combines the heat exchanger surface with a centrifugal fan, it’s theoretically possible to achieve a 10x better overall system efficiency than currently available air conditioners. With the US HVAC market valued at over $20B, we initially plan to target the room a/c market and offer customers an extremely efficient, quiet, lightweight, and stylistic product.

Infinite Cooling

Grant in 2020
Founded in 2017, Infinite Cooling specializes in wastewater management and recycling. It uses high-voltage electric fields to capture and recycle vast amounts of water that would otherwise be lost at industrial facilities like power plants, data centers, and factories.

Infinite Cooling

Grant in 2019
Founded in 2017, Infinite Cooling specializes in wastewater management and recycling. It uses high-voltage electric fields to capture and recycle vast amounts of water that would otherwise be lost at industrial facilities like power plants, data centers, and factories.

Nativus

Grant in 2019
Nativus is a hardware technology company developing a hyper-efficient air-conditioner for commercial and residential applications in the heating and cooling industry. Current technologies have remained stagnant for decades, receiving only incremental improvements over the past 50 years. However, through our patent-pending technology which combines the heat exchanger surface with a centrifugal fan, it’s theoretically possible to achieve a 10x better overall system efficiency than currently available air conditioners. With the US HVAC market valued at over $20B, we initially plan to target the room a/c market and offer customers an extremely efficient, quiet, lightweight, and stylistic product.

Dynalene

Grant in 2018
Dynalene is a developer and supplier of industrial heat transfer fluids and coolants for ultra-low temperature cryogenic and other demanding applications. The company offers glycols, potassium formate, calcium chloride-based secondary refrigerants, and high-performance coolants, along with a range of high- and low-temperature fluids, nanodiamond products, and functionalized nanoparticle dispersions for water treatment, coatings, biomedical, and related uses. It provides laboratory services such as thermal and physical analysis, chemical testing, and materials/corrosion testing. Dynalene serves markets including fuel cells, solar and geothermal, HVAC, supermarket refrigeration, plastics processing, electronics, pharmaceutical, environmental testing, food and beverage, and wind tunnels, and markets its products via an online store. Based in Whitehall, Pennsylvania, the company focuses on cryogenic and precision cooling needs with chemistries spanning glycols, potassium formate, calcium chloride, hydrocarbons, and silicones.

Carnot Compression

Grant in 2017
Carnot Compression is a manufacturer specializing in energy-efficient air and gas compression solutions, particularly for oil-free applications. The company employs a proprietary isothermal compression process that utilizes water's thermal capacity to absorb heat generated during compression, resulting in significant energy savings compared to conventional methods. By creating millions of tiny gas bubbles surrounded by water, Carnot's technology can absorb substantial amounts of heat, making it capable of delivering low-temperature, oil-free compressed gas. This innovative approach addresses a diverse range of industrial needs, including applications in refrigeration, liquefied natural gas, compressed natural gas transportation, and energy storage. With a focus on sustainability, Carnot Compression is positioned to capitalize on a $30 billion global market opportunity, serving various sectors such as food and life sciences.

SkyCool Systems

Grant in 2017
SkyCool Systems Inc. is a San Francisco-based company that specializes in developing and manufacturing innovative cooling and refrigeration systems. Incorporated in 2016, the company focuses on delivering sustainable and energy-efficient cooling solutions aimed at reducing energy costs and carbon footprints. SkyCool Systems has pioneered the technology of radiative cooling, utilizing specially designed optical films that reflect sunlight and emit thermal radiation effectively. This allows their rooftop cooling panels to operate passively during the hottest hours of the day. The panels can be integrated with existing air conditioning and refrigeration systems, serving as an add-on or, in some cases, replacing traditional air condensing units. Through this approach, SkyCool Systems is contributing to a transition towards a cleaner and more sustainable future.

Innovas Technologies

Grant in 2016
Innovas Technologies provides automatic condenser and chiller tube cleaning systems that improve energy efficiency and reduce maintenance. The company's system provides condenser tube cleaning systems for on-load cleaning of surface condensers in steam or combined cycle plants, cleans heat exchangers naturally and sustainably without costly process shutdowns or chemicals, and enables its clients to improve the energy efficiency of water-cooled chillers and central chilled water plants in a cost-effective manner.

Dynalene

Grant in 2016
Dynalene is a developer and supplier of industrial heat transfer fluids and coolants for ultra-low temperature cryogenic and other demanding applications. The company offers glycols, potassium formate, calcium chloride-based secondary refrigerants, and high-performance coolants, along with a range of high- and low-temperature fluids, nanodiamond products, and functionalized nanoparticle dispersions for water treatment, coatings, biomedical, and related uses. It provides laboratory services such as thermal and physical analysis, chemical testing, and materials/corrosion testing. Dynalene serves markets including fuel cells, solar and geothermal, HVAC, supermarket refrigeration, plastics processing, electronics, pharmaceutical, environmental testing, food and beverage, and wind tunnels, and markets its products via an online store. Based in Whitehall, Pennsylvania, the company focuses on cryogenic and precision cooling needs with chemistries spanning glycols, potassium formate, calcium chloride, hydrocarbons, and silicones.

Carnot Compression

Grant in 2015
Carnot Compression is a manufacturer specializing in energy-efficient air and gas compression solutions, particularly for oil-free applications. The company employs a proprietary isothermal compression process that utilizes water's thermal capacity to absorb heat generated during compression, resulting in significant energy savings compared to conventional methods. By creating millions of tiny gas bubbles surrounded by water, Carnot's technology can absorb substantial amounts of heat, making it capable of delivering low-temperature, oil-free compressed gas. This innovative approach addresses a diverse range of industrial needs, including applications in refrigeration, liquefied natural gas, compressed natural gas transportation, and energy storage. With a focus on sustainability, Carnot Compression is positioned to capitalize on a $30 billion global market opportunity, serving various sectors such as food and life sciences.

MaxQ

Grant in 2015
MaxQ designs and manufactures validated cold chain packaging and insulated shipping containers for the life sciences and healthcare sectors. The company provides thermal control packaging for blood, biologics, pharmaceuticals, and clinical-trial shipments, with optimized blood packaging and validated shipping and storage systems. It offers pre-qualified pack-outs for up to three days, validated for customer-specific ambient exposures, and supports reusable and custom packaging to reduce product loss from breakage and poor insulation. Founded in 2012 and based in Stillwater, Oklahoma, MaxQ serves customers across the life science supply chain, enabling safe transport of temperature-sensitive materials.

Nascent Devices

Grant in 2013
Nascent Devices is a company focused on the development of advanced ferroelectric and electrocaloric technologies aimed at enhancing energy efficiency and reducing environmental impact. The firm specializes in vapor-based compression systems that utilize electrocaloric materials to achieve efficient cooling through direct electricity. In addition to these cooling modules, Nascent Devices also produces electrocaloric polymer films, heat flux sensors, magnetic sensors, energy harvesting devices, and high-pressure transducers. By commercializing these innovative technologies, the company aims to provide solutions that improve energy efficiency across various industries.

MaxQ

Grant in 2013
MaxQ designs and manufactures validated cold chain packaging and insulated shipping containers for the life sciences and healthcare sectors. The company provides thermal control packaging for blood, biologics, pharmaceuticals, and clinical-trial shipments, with optimized blood packaging and validated shipping and storage systems. It offers pre-qualified pack-outs for up to three days, validated for customer-specific ambient exposures, and supports reusable and custom packaging to reduce product loss from breakage and poor insulation. Founded in 2012 and based in Stillwater, Oklahoma, MaxQ serves customers across the life science supply chain, enabling safe transport of temperature-sensitive materials.

Promethean Power Systems

Grant in 2013
Promethean Power Systems, Inc. specializes in designing and manufacturing refrigeration systems tailored for cold-storage and milk chilling applications, particularly in off-grid and partially electrified regions. Founded in 2007 and headquartered in Somerville, Massachusetts, with an office in Pune, India, the company provides a range of products including milk chillers, cold storage units, solar add-ons, and smart monitoring solutions. Its innovative systems are aimed at dairy processors and individual farmers, helping them to reduce spoilage and enhance the quality of milk collected from rural areas. By enabling the preservation of milk at the village level, Promethean's technology not only lowers transportation costs for processors but also increases farmer incomes. The refrigeration systems are designed to operate on grid power and are equipped with a generator backup, with plans to incorporate thermal battery storage for greater efficiency in the future.

Thermavant Technologies

Grant in 2012
ThermAvant Technologies specializes in the design and manufacture of advanced heat transfer products, with a focus on oscillating heat pipes. Drawing on decades of research and development, the company aims to enhance the size, weight, performance, and cost-effectiveness of energy and technology platforms. ThermAvant's product offerings include oscillating heat pipes, liquid cold plates, and ejector refrigeration systems, which are specifically engineered to support a variety of applications, ranging from aerospace to consumer goods. The company provides comprehensive services that include the design, analysis, fabrication, and testing of custom thermal solutions, thereby enabling clients to effectively manage heat transfer challenges in their respective fields.
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