National Science Foundation

The National Science Foundation is an independent federal agency in the United States that funds and supports research and education in science and engineering. It funds fundamental research and education across all fields of science and engineering and administers non-dilutive funding programs to aid early‑stage technology development, helping translate discoveries into commercially viable products and services. Through grants and fellowships, the NSF supports researchers, educators, and startups, contributing to innovation and U.S. competitiveness. The agency operates with a substantial budget to advance science, engineering, and STEM education nationwide.

James Donlon

Program Director

Sean L. Jones

Assistant Director for Mathematical and Physical Sciences

Debasis Majumdar

Program Director

Graciela Narcho

Staff Associate

Sethuraman Panchanathan

Director

Past deals in Skincare

Superior Nano

Grant in 2022
Superior Nano is a skincare manufacturer specializing in topical products that enhance skin appearance and health. Utilizing proprietary nanotechnology, their serums and moisturizers target aging, radiance, and firmness, offering consumers an effective alternative to invasive procedures.

Canomiks

Grant in 2022
Canomiks offers a genomics, bioinformatics, and AI-driven platform that empowers companies in functional food, dietary supplements, and skincare sectors to create safe and effective products. Its long-term goal is to make 'food as medicine' a reality.

SunFly Brands

Grant in 2021
SunFly Brands, Inc., established in Seattle, Washington in 2016, specializes in manufacturing UV-sensitive color-changing ink for invisible stamps designed to be worn underneath sunscreen. These stamps saturate with color when exposed to ultraviolet rays, indicating the need to reapply sunscreen. The company aims to address the prevalent issue of insufficient sunscreen application and infrequent reapplications, which contribute significantly to sunburns, skin cancers, and age-related skin changes.

Radiosight

Grant in 2021
Radiosight develops ultra-wide imaging technology to aid in diagnosing skin cancer and guiding surgical decisions. Founded in 2020 and based in Hoboken, New Jersey, the company integrates ultra-wide, high-resolution imaging with a handheld 3D visualization device to enhance surgical precision during excisions and support informed decision-making. Its platform captures subsurface structures and detailed tissue morphology, enabling clinicians to assess the depth and boundaries of suspicious lesions prior to biopsy and to plan treatments accordingly.

Seaspire Skincare

Grant in 2021
Seaspire Skincare specializes in developing multifunctional colorants and actives inspired by ocean biodiversity. Its flagship product, Xanthochrome, offers broader UV protection and aims to replace harmful ingredients in skincare products, promoting sustainability and reduced adverse effects on human and marine health.

BioAesthetics

Grant in 2021
BioAesthetics develops tissue-engineered nipple-areolar complex grafts to support breast reconstruction after mastectomy. The graft is designed as a scaffold for the patient's own cells to populate and regenerate the nipple and areola during reconstruction, aiming to improve cosmetic and reconstructive outcomes. The company originated as a Tulane University spin-out and was founded in 2015.

ZeoVation

Grant in 2020
Founded in 2016, ZeoVation specializes in manufacturing nanozeolites and hierarchical zeolites. These materials enhance consumer products such as skincare lotions, sunscreens, laundry detergents, water softeners, and filtration systems by improving efficiency.

BENANOVA

Grant in 2020
BENANOVA develops safer antimicrobial products and eco-friendly materials for disinfectant, cosmetic, agricultural, and textile applications. Its Environmentally-benign Nanoparticles provide high efficacy with a degradable design, offering environmentally friendly replacements for silver nanoparticle antimicrobials and the potential to reduce chemical use in crop protection by up to 90%. The company also uses lignin-based, biodegradable materials from bio-renewable sources to support sustainable agriculture and specialty textiles, combining strong performance with reduced environmental impact.

Onederings Lavender Farm

Grant in 2020
Onederings Lavender Farm, located in Clarksville, Ohio, specializes in the cultivation of lavender and the production of high-quality lavender-based products. The farm focuses on creating boutique skin and home care items crafted from its homegrown lavender, utilizing evidence-based natural ingredients. This commitment allows Onederings to offer customers premium beauty products that emphasize quality and effectiveness. The company aims to provide a unique selection of dried lavender and fine lavender products, catering to individuals seeking natural and luxurious options for personal care and home use.

BENANOVA

Grant in 2020
BENANOVA develops safer antimicrobial products and eco-friendly materials for disinfectant, cosmetic, agricultural, and textile applications. Its Environmentally-benign Nanoparticles provide high efficacy with a degradable design, offering environmentally friendly replacements for silver nanoparticle antimicrobials and the potential to reduce chemical use in crop protection by up to 90%. The company also uses lignin-based, biodegradable materials from bio-renewable sources to support sustainable agriculture and specialty textiles, combining strong performance with reduced environmental impact.

HelioBioSys

Grant in 2020
HelioBioSys is a biotechnology company that specializes in marine cyanobacteria. The company uses marine cyanobacteria that grow on air, seawater, and sunlight. They produce a variety of complex biopolymers. HelioBioSys has developed cost-effective ways to harvest and process them into concentrated polysaccharides and hydrogels. These sustainably-derived biomaterials have applications in cosmetics, sunscreens and bioplastics.

GlycoSurf

Grant in 2019
GlycoSurf, established in 2013, is a specialty chemicals company that produces bio-inspired surfactants, specifically focusing on rhamnolipids. These are high-purity, non-toxic, biodegradable glycolipids with tailored chemical properties. GlycoSurf's products are used in various applications, notably in the formulation of personal-care products, contributing to a more sustainable chemical industry.

Gadusol Laboratories

Grant in 2019
Gadusol Laboratories is a startup based in Corvallis, Oregon, that uses patented synthetic biology to produce natural sunscreen antioxidants derived from marine organisms. The company manufactures non‑toxic sunscreens that incorporate gadusol, a compound used by aquatic life to prevent sunburn, offering safe and effective sun protection while addressing environmental and health concerns associated with conventional sunscreen ingredients.

Gadusol Laboratories

Seed Round in 2019
Gadusol Laboratories is a startup based in Corvallis, Oregon, that uses patented synthetic biology to produce natural sunscreen antioxidants derived from marine organisms. The company manufactures non‑toxic sunscreens that incorporate gadusol, a compound used by aquatic life to prevent sunburn, offering safe and effective sun protection while addressing environmental and health concerns associated with conventional sunscreen ingredients.

Bluelene

Grant in 2019
Bluelene is an online retailer specializing in face care products. Its patented ingredient, methylene blue, penetrates human cells to enhance skin health, repair age-related damage, and protect against sun damage.

ZeoVation

Grant in 2019
Founded in 2016, ZeoVation specializes in manufacturing nanozeolites and hierarchical zeolites. These materials enhance consumer products such as skincare lotions, sunscreens, laundry detergents, water softeners, and filtration systems by improving efficiency.

Cybele Microbiome

Grant in 2019
Cybele Microbiome is a biotechnology company focused on enhancing skin health through precision control of the microbiome. The company utilizes a proprietary AI platform that integrates machine learning with advanced biotechnology and unique data sources to identify natural prebiotics. These prebiotics are designed to nourish the microbiome, leading to the development of customized skincare products. By employing genetic sequencing methods and sustainable nutrient sources, Cybele Microbiome aims to strengthen the skin's natural barrier and promote overall health and longevity. The innovative approach combines artificial intelligence with microbiome science to revolutionize skincare, enabling consumers to maintain the integrity of their skin through effective and conscientious skincare solutions.

HelioBioSys

Grant in 2018
HelioBioSys is a biotechnology company that specializes in marine cyanobacteria. The company uses marine cyanobacteria that grow on air, seawater, and sunlight. They produce a variety of complex biopolymers. HelioBioSys has developed cost-effective ways to harvest and process them into concentrated polysaccharides and hydrogels. These sustainably-derived biomaterials have applications in cosmetics, sunscreens and bioplastics.

BENANOVA

Grant in 2018
BENANOVA develops safer antimicrobial products and eco-friendly materials for disinfectant, cosmetic, agricultural, and textile applications. Its Environmentally-benign Nanoparticles provide high efficacy with a degradable design, offering environmentally friendly replacements for silver nanoparticle antimicrobials and the potential to reduce chemical use in crop protection by up to 90%. The company also uses lignin-based, biodegradable materials from bio-renewable sources to support sustainable agriculture and specialty textiles, combining strong performance with reduced environmental impact.

Gadusol Laboratories

Grant in 2017
Gadusol Laboratories is a startup based in Corvallis, Oregon, that uses patented synthetic biology to produce natural sunscreen antioxidants derived from marine organisms. The company manufactures non‑toxic sunscreens that incorporate gadusol, a compound used by aquatic life to prevent sunburn, offering safe and effective sun protection while addressing environmental and health concerns associated with conventional sunscreen ingredients.

InnovaNutra

Grant in 2017
InnovaNutra, established in 2015 and based in Davis, California, specializes in the development of bio-based encapsulation technology for enhancing nutrient and phytochemical bioaccessibility. The company's core product is a cloud-based SaaS suite offering formulations that concentrate naturally occurring health-promoting nutrients while eliminating associated bitterness or astringency. This enables businesses to improve shelf-life and delivery of susceptible natural ingredients, facilitating the creation of clean label products in both food and cosmetic sectors.

Renuvix

Grant in 2016
Renuvix is a manufacturer of bio-based resins and polymers, catering to formulators in diverse industries such as paints and coatings, composites, adhesives, cosmetics, and personal care products. Founded in 2013 and headquartered in Fargo, North Dakota, the company focuses on producing resin and synthetic rubber that enable formulators to minimize volatile organic compounds in their products and enhance cross-link density in thermoset materials. Through its innovative solutions, Renuvix supports the development of more sustainable and environmentally friendly formulations across various applications.

InnovaNutra

Grant in 2015
InnovaNutra, established in 2015 and based in Davis, California, specializes in the development of bio-based encapsulation technology for enhancing nutrient and phytochemical bioaccessibility. The company's core product is a cloud-based SaaS suite offering formulations that concentrate naturally occurring health-promoting nutrients while eliminating associated bitterness or astringency. This enables businesses to improve shelf-life and delivery of susceptible natural ingredients, facilitating the creation of clean label products in both food and cosmetic sectors.

Renuvix

Grant in 2014
Renuvix is a manufacturer of bio-based resins and polymers, catering to formulators in diverse industries such as paints and coatings, composites, adhesives, cosmetics, and personal care products. Founded in 2013 and headquartered in Fargo, North Dakota, the company focuses on producing resin and synthetic rubber that enable formulators to minimize volatile organic compounds in their products and enhance cross-link density in thermoset materials. Through its innovative solutions, Renuvix supports the development of more sustainable and environmentally friendly formulations across various applications.

Itaconix

Grant in 2014
Itaconix designs and manufactures bio-based polymers used in home care, personal care, industrial, and other applications. Its products are derived from itaconic acid, offering safety, performance, and sustainability advantages.

Rubitection

Grant in 2013
Rubitection is a medical technology company that develops AI-powered skin health monitoring and care-management solutions for wound care, dermatology, and cosmetic applications. The company offers a handheld system and related assessment tools designed to detect early signs of skin breakdown, including bedsores, diabetic foot ulcers, and other chronic dermatological conditions, enabling caregivers, physicians, and nurses to monitor risk and intervene early. Its platform provides data-driven insights to support assessment, prevention, and treatment of chronic wounds such as diabetic foot ulcers, vascular leg ulcers, psoriasis, and eczema, with the aim of improving patient outcomes and reducing care costs. Rubitection positions itself as a global standard system for skin health monitoring and care management, and is based in Pittsburgh, Pennsylvania.

Itaconix

Grant in 2012
Itaconix designs and manufactures bio-based polymers used in home care, personal care, industrial, and other applications. Its products are derived from itaconic acid, offering safety, performance, and sustainability advantages.
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