Celcuity Inc. is a clinical-stage biotechnology company based in Minneapolis, Minnesota, focused on advancing cancer care through innovative diagnostic and therapeutic solutions. The company's CELsignia diagnostic platform analyzes living tumor cells from patients to identify the specific abnormal cellular processes driving their cancer, enabling personalized treatment options. Celcuity is developing the CELsignia HSF test to diagnose new sub-types of HER2-negative breast cancer, as well as the CELsignia MP test to identify multiple cancer sub-types across various types, including breast, lung, colon, ovarian, kidney, and bladder cancers. In addition to its diagnostic efforts, Celcuity is advancing a lead therapeutic candidate, gedatolisib, a potent pan-PI3K and mTOR inhibitor, which is currently being evaluated in a Phase 3 clinical trial for patients with HR+/HER2- advanced breast cancer. Founded in 2011, Celcuity aims to transform the treatment landscape for patients with cancer by providing targeted therapies tailored to their unique disease profiles.
NeueHealth is a health care service platform that focuses on improving patient experiences and outcomes through a combination of technology and local healthcare resources. It operates 61 affiliated primary care clinics that deliver both virtual and in-person clinical care to nearly 75,000 unique patients. NeueHealth is part of Bright Health Group, which also offers Medicare and commercial health plan products to approximately 623,000 consumers across 14 states. The company aims to reduce healthcare costs while enhancing access and quality of care by aligning the interests of consumers, providers, and payers. Founded in 2015 and based in Minneapolis, Minnesota, NeueHealth leverages intelligent technology to connect users with healthcare services and providers effectively.
Relievant Medsystems, Inc. is a medical device company focused on addressing chronic axial low back pain through a minimally invasive procedure known as Intracept. This innovative treatment specifically targets the basivertebral nerve, utilizing radio-frequency energy delivered through a small access tube into the vertebral body to ablate the nerve. The procedure is performed under real-time fluoroscopic guidance, ensuring precision and safety. Founded in 2004 and headquartered in Minneapolis, Minnesota, with an additional office in Sunnyvale, California, Relievant aims to provide low-risk therapeutic solutions that significantly improve the quality of life for patients suffering from vertebrogenic low back pain.
NeueHealth is a health care service platform that focuses on improving patient experiences and outcomes through a combination of technology and local healthcare resources. It operates 61 affiliated primary care clinics that deliver both virtual and in-person clinical care to nearly 75,000 unique patients. NeueHealth is part of Bright Health Group, which also offers Medicare and commercial health plan products to approximately 623,000 consumers across 14 states. The company aims to reduce healthcare costs while enhancing access and quality of care by aligning the interests of consumers, providers, and payers. Founded in 2015 and based in Minneapolis, Minnesota, NeueHealth leverages intelligent technology to connect users with healthcare services and providers effectively.
CVRx, Inc. is a medical device company based in Minneapolis, Minnesota, that specializes in implantable technology for treating high blood pressure and heart failure. The company develops Barostim, a proprietary neuromodulation therapy that activates the body's natural reflexes to regulate blood pressure and address the progression of heart failure. This therapy is delivered through a long-lasting implant system that is tailored to meet individual patient needs. CVRx also manufactures the Rheos implantable pulse generator and associated components, which facilitate the delivery of activation energy to the carotid arteries. Founded in 2000, CVRx primarily serves patients and healthcare professionals in the United States and several European countries, focusing on minimally invasive solutions for cardiovascular diseases.
Cardionomic, Inc. develops a catheter-based medical device aimed at treating acute decompensated heart failure (ADHF) through neuromodulation. This innovative technology electrically stimulates cardiac nerves to enhance the heart's pumping action, which is crucial for improving cardiac output, renal blood flow, urine production, and pharmacological tolerance. The device is inserted into the right pulmonary artery via the internal jugular vein and selectively stimulates autonomic nerves that control ventricular contractility without altering heart rate. By targeting the root cause of ADHF, Cardionomic's therapy not only increases contractility but also leads to reductions in plasma norepinephrine and B-type natriuretic peptide, both of which are biomarkers of chronic heart failure. Established in 2007 and headquartered in New Brighton, Minnesota, Cardionomic aims to enhance patient outcomes in acute heart failure management.
NeueHealth is a health care service platform that focuses on improving patient experiences and outcomes through a combination of technology and local healthcare resources. It operates 61 affiliated primary care clinics that deliver both virtual and in-person clinical care to nearly 75,000 unique patients. NeueHealth is part of Bright Health Group, which also offers Medicare and commercial health plan products to approximately 623,000 consumers across 14 states. The company aims to reduce healthcare costs while enhancing access and quality of care by aligning the interests of consumers, providers, and payers. Founded in 2015 and based in Minneapolis, Minnesota, NeueHealth leverages intelligent technology to connect users with healthcare services and providers effectively.
CVRx, Inc. is a medical device company based in Minneapolis, Minnesota, that specializes in implantable technology for treating high blood pressure and heart failure. The company develops Barostim, a proprietary neuromodulation therapy that activates the body's natural reflexes to regulate blood pressure and address the progression of heart failure. This therapy is delivered through a long-lasting implant system that is tailored to meet individual patient needs. CVRx also manufactures the Rheos implantable pulse generator and associated components, which facilitate the delivery of activation energy to the carotid arteries. Founded in 2000, CVRx primarily serves patients and healthcare professionals in the United States and several European countries, focusing on minimally invasive solutions for cardiovascular diseases.
NeueHealth is a health care service platform that focuses on improving patient experiences and outcomes through a combination of technology and local healthcare resources. It operates 61 affiliated primary care clinics that deliver both virtual and in-person clinical care to nearly 75,000 unique patients. NeueHealth is part of Bright Health Group, which also offers Medicare and commercial health plan products to approximately 623,000 consumers across 14 states. The company aims to reduce healthcare costs while enhancing access and quality of care by aligning the interests of consumers, providers, and payers. Founded in 2015 and based in Minneapolis, Minnesota, NeueHealth leverages intelligent technology to connect users with healthcare services and providers effectively.
Relievant Medsystems, Inc. is a medical device company focused on addressing chronic axial low back pain through a minimally invasive procedure known as Intracept. This innovative treatment specifically targets the basivertebral nerve, utilizing radio-frequency energy delivered through a small access tube into the vertebral body to ablate the nerve. The procedure is performed under real-time fluoroscopic guidance, ensuring precision and safety. Founded in 2004 and headquartered in Minneapolis, Minnesota, with an additional office in Sunnyvale, California, Relievant aims to provide low-risk therapeutic solutions that significantly improve the quality of life for patients suffering from vertebrogenic low back pain.
Metavention, Inc., established in 2012 and headquartered in Dover, Delaware, specializes in the development of trans-catheter devices aimed at modulating sympathetic nervous system activity. These innovative devices address the issues of over-active sympathetic nerves that contribute to elevated glucose levels and abnormal liver function. By employing standard interventional vascular techniques, Metavention provides healthcare professionals with a novel tool for diagnosing and treating patients with Type 2 diabetes. The company focuses on enhancing treatment options for this condition, ultimately improving patient outcomes.
NeueHealth is a health care service platform that focuses on improving patient experiences and outcomes through a combination of technology and local healthcare resources. It operates 61 affiliated primary care clinics that deliver both virtual and in-person clinical care to nearly 75,000 unique patients. NeueHealth is part of Bright Health Group, which also offers Medicare and commercial health plan products to approximately 623,000 consumers across 14 states. The company aims to reduce healthcare costs while enhancing access and quality of care by aligning the interests of consumers, providers, and payers. Founded in 2015 and based in Minneapolis, Minnesota, NeueHealth leverages intelligent technology to connect users with healthcare services and providers effectively.
Relievant Medsystems, Inc. is a medical device company focused on addressing chronic axial low back pain through a minimally invasive procedure known as Intracept. This innovative treatment specifically targets the basivertebral nerve, utilizing radio-frequency energy delivered through a small access tube into the vertebral body to ablate the nerve. The procedure is performed under real-time fluoroscopic guidance, ensuring precision and safety. Founded in 2004 and headquartered in Minneapolis, Minnesota, with an additional office in Sunnyvale, California, Relievant aims to provide low-risk therapeutic solutions that significantly improve the quality of life for patients suffering from vertebrogenic low back pain.
Rotation Medical Inc. specializes in the development of a minimally invasive rotator cuff implant system aimed at treating rotator cuff disease. The company's innovative implant consists of a collagen scaffold designed to be affixed to damaged rotator cuff tendons, providing effective management and protection for tendon injuries. This system offers a surgical solution for patients with small rotator cuff tears and serves as an additional protective layer for larger tears. Founded in 2006 and headquartered in Plymouth, Minnesota, Rotation Medical was previously known as Denali Medical Inc. and rebranded in March 2010. As of December 2017, the company operates as a subsidiary of Smith & Nephew plc.
NeueHealth is a health care service platform that focuses on improving patient experiences and outcomes through a combination of technology and local healthcare resources. It operates 61 affiliated primary care clinics that deliver both virtual and in-person clinical care to nearly 75,000 unique patients. NeueHealth is part of Bright Health Group, which also offers Medicare and commercial health plan products to approximately 623,000 consumers across 14 states. The company aims to reduce healthcare costs while enhancing access and quality of care by aligning the interests of consumers, providers, and payers. Founded in 2015 and based in Minneapolis, Minnesota, NeueHealth leverages intelligent technology to connect users with healthcare services and providers effectively.
Cardionomic, Inc. develops a catheter-based medical device aimed at treating acute decompensated heart failure (ADHF) through neuromodulation. This innovative technology electrically stimulates cardiac nerves to enhance the heart's pumping action, which is crucial for improving cardiac output, renal blood flow, urine production, and pharmacological tolerance. The device is inserted into the right pulmonary artery via the internal jugular vein and selectively stimulates autonomic nerves that control ventricular contractility without altering heart rate. By targeting the root cause of ADHF, Cardionomic's therapy not only increases contractility but also leads to reductions in plasma norepinephrine and B-type natriuretic peptide, both of which are biomarkers of chronic heart failure. Established in 2007 and headquartered in New Brighton, Minnesota, Cardionomic aims to enhance patient outcomes in acute heart failure management.
Code42 Software, Inc. is an enterprise SaaS provider specializing in cloud endpoint data protection and security solutions for the business and education sectors. The company's flagship product, Code42 CrashPlan, offers continuous backup of distributed end-user data, enabling organizations to maintain visibility and control over their information. Additionally, Code42 provides Internet2 NET+ CrashPlan, a tailored endpoint backup service for U.S. higher education institutions, and Code42 Next-Gen DLP, a data loss protection solution designed for resource-constrained IT and security teams. The SaaS solution Incydr focuses on safeguarding organizations' intellectual property and sensitive information. With a strategic partnership with Exabeam, Code42 has established itself as a trusted provider, serving over 50,000 organizations globally. Founded in 2001 and headquartered in Minneapolis, Minnesota, the company is backed by prominent investors, including Accel Partners and NEA.
Rotation Medical Inc. specializes in the development of a minimally invasive rotator cuff implant system aimed at treating rotator cuff disease. The company's innovative implant consists of a collagen scaffold designed to be affixed to damaged rotator cuff tendons, providing effective management and protection for tendon injuries. This system offers a surgical solution for patients with small rotator cuff tears and serves as an additional protective layer for larger tears. Founded in 2006 and headquartered in Plymouth, Minnesota, Rotation Medical was previously known as Denali Medical Inc. and rebranded in March 2010. As of December 2017, the company operates as a subsidiary of Smith & Nephew plc.
CVRx, Inc. is a medical device company based in Minneapolis, Minnesota, that specializes in implantable technology for treating high blood pressure and heart failure. The company develops Barostim, a proprietary neuromodulation therapy that activates the body's natural reflexes to regulate blood pressure and address the progression of heart failure. This therapy is delivered through a long-lasting implant system that is tailored to meet individual patient needs. CVRx also manufactures the Rheos implantable pulse generator and associated components, which facilitate the delivery of activation energy to the carotid arteries. Founded in 2000, CVRx primarily serves patients and healthcare professionals in the United States and several European countries, focusing on minimally invasive solutions for cardiovascular diseases.
Apnex Medical, Inc. manufactures and markets medical devices such as implants for the treatment of obstructive sleep apnea. Apnex Medical, Inc. was incorporated in 2006 and is based in Saint Paul, Minnesota.
Relievant Medsystems, Inc. is a medical device company focused on addressing chronic axial low back pain through a minimally invasive procedure known as Intracept. This innovative treatment specifically targets the basivertebral nerve, utilizing radio-frequency energy delivered through a small access tube into the vertebral body to ablate the nerve. The procedure is performed under real-time fluoroscopic guidance, ensuring precision and safety. Founded in 2004 and headquartered in Minneapolis, Minnesota, with an additional office in Sunnyvale, California, Relievant aims to provide low-risk therapeutic solutions that significantly improve the quality of life for patients suffering from vertebrogenic low back pain.
Apnex Medical, Inc. manufactures and markets medical devices such as implants for the treatment of obstructive sleep apnea. Apnex Medical, Inc. was incorporated in 2006 and is based in Saint Paul, Minnesota.
BridgePoint Medical, a private company with headquarters in Minneapolis, Minnesota, is focused on developing innovative and proprietary technology in the field of interventional cardiology for access to and treatment of chronic total occlusions.
Anulex Technologies focus on developing proprietary medical technology to repair and seal the soft tissue of the spine (anulus) for patients undergoing a surgical procedure to remove a herniated disc (discectomy).
Apnex Medical, Inc. manufactures and markets medical devices such as implants for the treatment of obstructive sleep apnea. Apnex Medical, Inc. was incorporated in 2006 and is based in Saint Paul, Minnesota.
BridgePoint Medical, a private company with headquarters in Minneapolis, Minnesota, is focused on developing innovative and proprietary technology in the field of interventional cardiology for access to and treatment of chronic total occlusions.
Anulex Technologies focus on developing proprietary medical technology to repair and seal the soft tissue of the spine (anulus) for patients undergoing a surgical procedure to remove a herniated disc (discectomy).
CVRx, Inc. is a medical device company based in Minneapolis, Minnesota, that specializes in implantable technology for treating high blood pressure and heart failure. The company develops Barostim, a proprietary neuromodulation therapy that activates the body's natural reflexes to regulate blood pressure and address the progression of heart failure. This therapy is delivered through a long-lasting implant system that is tailored to meet individual patient needs. CVRx also manufactures the Rheos implantable pulse generator and associated components, which facilitate the delivery of activation energy to the carotid arteries. Founded in 2000, CVRx primarily serves patients and healthcare professionals in the United States and several European countries, focusing on minimally invasive solutions for cardiovascular diseases.
Apnex Medical, Inc. manufactures and markets medical devices such as implants for the treatment of obstructive sleep apnea. Apnex Medical, Inc. was incorporated in 2006 and is based in Saint Paul, Minnesota.
CVRx, Inc. is a medical device company based in Minneapolis, Minnesota, that specializes in implantable technology for treating high blood pressure and heart failure. The company develops Barostim, a proprietary neuromodulation therapy that activates the body's natural reflexes to regulate blood pressure and address the progression of heart failure. This therapy is delivered through a long-lasting implant system that is tailored to meet individual patient needs. CVRx also manufactures the Rheos implantable pulse generator and associated components, which facilitate the delivery of activation energy to the carotid arteries. Founded in 2000, CVRx primarily serves patients and healthcare professionals in the United States and several European countries, focusing on minimally invasive solutions for cardiovascular diseases.
BridgePoint Medical, a private company with headquarters in Minneapolis, Minnesota, is focused on developing innovative and proprietary technology in the field of interventional cardiology for access to and treatment of chronic total occlusions.
Anulex Technologies focus on developing proprietary medical technology to repair and seal the soft tissue of the spine (anulus) for patients undergoing a surgical procedure to remove a herniated disc (discectomy).
BridgePoint Medical, a private company with headquarters in Minneapolis, Minnesota, is focused on developing innovative and proprietary technology in the field of interventional cardiology for access to and treatment of chronic total occlusions.
Cassatt Corporation provides software solutions and technologies for operating green data centers. It offers Active Response software product line, which is based on Active Power Management technology that pools physical and virtual server resources for efficient utilization and uses policy-driven controls to off and on servers when needed. The company provides Cassatt Active Response products in four editions for increasing energy efficiency; application resiliency; high application availability; server workload management in production environments; and optimal control of data center resources throughout an organization and across multiple geographies. It also offers server consolidation, virtualization control, J2EE/SOA optimization, IT operations efficiency, capacity on demand, and utility computing solutions. In addition, the company offers Active Power Management Assessment to produce an Active Power Management pilot/deployment architecture and a TCO strategy; Active Power Management Validation, which helps to define and assess broader requirements/goals for deployment and validates the product's capability; Active Power Management QuickStart, which includes installation and deployment consultation, on-site education, and a workshop tailored to specific environments; Active Power Management Deployment Office, which provides project planning, best practices, and Active Power Management implementation guidance through an on-site team; and Active Power Management Deployment Services, which Focuses on supporting needs for Active Power Management deployment on a time and materials basis. The company was founded in 2003 and is headquartered in San Jose, California with additional offices in New York; Washington, the District of Columbia; Colorado Springs, Colorado; Mendota Heights, Minnesota; Chicago, Illinois; and London. As of June 2, 2009, Cassatt Corporation operates as a subsidiary of CA, Inc.
Prospex Medical, now dormant, was a medical device incubator focused on innovating and incubating novel medical technologies. With an emphasis on regulated medical devices and non-regulated (quasi-consumer) medical products, Prospex Medical explored a wide variety of opportunities in the health care market. Through a process of market identification, clinical and technical research, physician collaboration, intellectual property generation, and proof of concept, Prospex Medical successfully created and spun-out two companies: BridgePoint Medical (www.bridgepointmedical.com) and Apnex Medical (www.apnexmedical.com).
LTCG is a leading provider of business process outsourcing to the insurance industry, with an emphasis on supporting long-term care products. LTCG serves over 50 insurers, including all of the top 10 carriers in the long-term care market. The company offers complete administrative support, including application processing, underwriting, policy administration, and claims and care management, as well as health and functional assessments. In addition, LTCG provides clients with unique insight about risk management built upon the industry’s largest database of long-term care underwriting and claims.
eBenX provide business-to-business e-commerce and connectivity solutions to employers and health plans for the purchase, eligibility administration and premium payment of group health insurance benefits. Through their proprietary and licensed technology, they facilitate the flow of eligibility and financial data between employers and health plans.
AneuRx
Venture Round in 1995
AneuRx provides stent-grafts for abdominal aortic aneurysm repair therapy. AneuRx develops surgical grafts for treating abdominal aortic aneurysms delivered via minimally invasive technologies.
Endocardial Solutions
Venture Round in 1993
Endocardial Solutions, Inc. ("ESI" or the "Company") designs, develops, and manufactures a minimally invasive diagnostic system that diagnoses, within the span of a few heartbeats, tachycardia, a potentially fatal abnormal heart rhythm. The Company believes that its proprietary EnSite catheter and clinical workstation (together, the "EnSite System") is a powerful new diagnostic tool that will enable electrophysiologists to rapidly and comprehensively map tachycardia and improve the selection of patient treatment options.