Numinus is a Vancouver-based company founded in 2019 by Payton Nyquvest and Stacey Wallin, specializing in psychedelic-centered therapeutic products and services. It integrates holistic healthcare approaches with neuro-technology to enhance patient care. Numinus operates a network of clinics, including Numinus Health, Mindspace Services, and the Neurology Center of Toronto, offering a range of services such as ketamine-assisted psychotherapy for conditions like depression, as well as neurological care and counseling by registered psychologists. The company is structured into several operational segments, including clinical research, its Canadian and US clinic networks, and corporate functions, with the majority of its revenue generated from the US segment. Through its laboratory and research and development initiatives, Numinus aims to advance the field of psychedelic therapy and improve mental health outcomes.
Diamond Therapeutics
Venture Round in 2023
Diamond Therapeutics is a Toronto-based company dedicated to developing novel therapies for mental health conditions. It focuses on harnessing the potential of psychedelic compounds, specifically sub-perceptual, non-hallucinogenic treatments, aiming to benefit a wide range of patients and maximize positive impact on global mental health.
Damona Pharmaceuticals
Seed Round in 2022
Damona Pharmaceuticals is a pre-clinical pharmaceutical company focused on treating and preventing cognitive deficits associated with various brain disorders and aging. The company develops small molecule therapeutics aimed at transforming the treatment of cognitive symptoms and restoring normal life functions for underserved and understudied mental health and aging populations. Their goal is to enable patients to potentially reverse impairments and resolve previously unresolvable symptoms.
Vessel Health
Series A in 2022
Vessel Health develops a user-friendly application that enables individuals to track and optimize their wellness at home. The platform offers doctor-designed test cards, an intuitive scanning app, tailored nutrition and supplement recommendations, and expert coaching based on urine-based testing.
Apollo Neuroscience
Series A in 2022
Apollo Neuroscience, Inc. is a Pittsburgh-based company that manufactures a clinically validated wearable wellness device designed to assist the body in recovering from chronic stress through gentle vibrations. Established in 2016, the company also offers an application that integrates neuroscience and machine learning to enhance heart rate variability, promoting improved routines for waking, focusing, unwinding, and engaging the parasympathetic nervous system. The product is marketed directly to consumers through online sales and is positioned as a wellness solution rather than a treatment for psychiatric disorders.
Psygen
Venture Round in 2022
Psygen is a manufacturer of pharmaceutical-grade psychedelic drug products specifically designed for clinical research and therapeutic applications. The company focuses on producing high-quality psychedelic substances to support healthcare researchers in accelerating the development of innovative treatments. By ensuring that these transformative products are understood and accessible, Psygen plays a crucial role in advancing the research landscape of psychedelic drugs, contributing to the potential benefits they may offer in various therapeutic settings.
Terran Biosciences
Venture Round in 2022
Terran Biosciences Inc. is a biotechnology company focused on developing innovative solutions for neurological and mental health disorders. Established in 2017 and headquartered in New York, the company offers a diverse range of products, including a therapeutics pipeline, a medical device program, and a precision medicine platform. Terran Biosciences aims to create impactful therapies and technologies that can significantly improve the quality of life for patients suffering from neurological and psychiatric conditions.
Tactogen
Seed Round in 2022
Founded in Palo Alto, California in 2020 by Matthew Baggott and Luke Pustejovsky, Tactogen is a biopharmaceutical startup dedicated to developing empathogen medicines. Its mission is to create safer, more effective prescription drugs that promote mental wellness and emotional connection.
Wake Network
Series A in 2021
Wake Network, Inc. is a Toronto-based company that specializes in clinical research and the development of wellness solutions through fungi and plant-based medicine. Founded in June 2018, it combines expertise from wellness professionals and advanced technology to create innovative healing benefits for the mind and body. The company has established a regenerative feedback loop, enabling it to conduct research, monitor outcomes, and integrate findings from clinical studies on a personalized basis. This approach positions Wake Network at the forefront of advancements in mental and holistic health.
CaaMTech is a drug discovery and optimization company focused on engineering psychedelic drugs. It creates and optimizes psychedelic compounds and formulations and provides drug safety and efficacy screening services. Based in Issaquah, Washington, the company was founded in 2019 and pursues rigorous science and continuous innovation to develop psychedelic medicines for conditions including depression and PTSD.
Sana Health
Convertible Note in 2021
Sana Health, Inc. is a digital health company based in Lafayette, Colorado, with an additional office in Mill Valley, California. Founded in 2015, the company specializes in developing bio-therapeutic devices designed to promote relaxation and alleviate pain and tension. Its flagship product, Sana, is a non-addictive mask and headphone combination that utilizes audiovisual stimulation to enhance the balance between the left and right sides of the brain, facilitating a deep meditative state. This device employs coordinated pulses of light and sound to guide users into relaxation, mimicking the benefits of long-term meditation practices. Sana Health is also engaged in multiple clinical studies, focusing on applications for conditions such as fibromyalgia and neuropathic pain, as well as trials related to anxiety and PTSD. The company offers its products for sale online and provides a mobile application accessible via major app platforms.
Merlyn Mind
Venture Round in 2021
Merlyn Mind is a technology company founded in 2018 and based in New York, focused on delivering AI-driven solutions to the education sector. Its flagship product, Merlyn, is an AI-powered digital assistant designed to enhance the teaching and learning experience. This assistant integrates custom hardware and software to understand natural voice commands and remote control inputs from educators, enabling them to manage multimedia applications effortlessly during lessons. By optimizing wake-word architecture and remote control functionality, Merlyn empowers teachers to leverage technology more intuitively in their classrooms, ultimately facilitating a more interactive and engaging learning environment.
Apollo Neuroscience
Series A in 2021
Apollo Neuroscience, Inc. is a Pittsburgh-based company that manufactures a clinically validated wearable wellness device designed to assist the body in recovering from chronic stress through gentle vibrations. Established in 2016, the company also offers an application that integrates neuroscience and machine learning to enhance heart rate variability, promoting improved routines for waking, focusing, unwinding, and engaging the parasympathetic nervous system. The product is marketed directly to consumers through online sales and is positioned as a wellness solution rather than a treatment for psychiatric disorders.
Woven Science
Seed Round in 2021
Woven Science is a life sciences platform focused on creating a comprehensive solution for mental healthcare, particularly through psychedelic therapeutics. The company aims to establish one of the first vertically integrated patient care systems in this field, encompassing all stages from drug development to clinic distribution. Woven Science emphasizes a model of mutuality, balancing purpose and profit, and is notable for its commitment to social responsibility by allocating 10% of its realized profits to nonprofits dedicated to supporting indigenous culture and ecosystem preservation. By building, backing, and incubating innovative companies within its ecosystem, Woven Science seeks to address the mental illness epidemic with a focus on delivering scalable and effective mental health outcomes throughout the treatment process.
Gilgamesh Pharmaceuticals
Series A in 2021
Gilgamesh Pharmaceuticals, Inc. is a preclinical biotechnology company based in New York, focused on developing innovative psychotropic drugs to address mental health issues. Founded in 2019, the company specializes in creating novel compounds that enhance the benefits of traditional psychedelics, improving parameters such as safety, tolerability, duration, and efficacy. Gilgamesh targets a range of neuropsychiatric conditions, including depression, anxiety, substance use disorders, and stress-related issues. With the growing global mental health crisis, the company aims to accelerate the development of new treatments that meet the urgent need for effective solutions in mental health care, leveraging its expertise in medicinal chemistry and drug development.
Bexson Biomedical
Series A in 2021
Bexson Biomedical is focused on developing an innovative subcutaneous delivery system for ketamine, aimed at treating chronic and acute pain disorders. The company’s lead product features a unique formulation of ketamine, which is administered through a minimally invasive, wearable infusion pump. This system addresses the limitations of existing ketamine preparations by helping to control overdosing risks and reducing the need for continuous monitoring. By enhancing the delivery method, Bexson Biomedical seeks to provide physicians with an effective tool for pain management.
People Science
Seed Round in 2021
People Science operates a technology-driven platform for clinical research in alternative medicine. It connects health-conscious individuals with medical professionals and scientists, facilitating the development of scientifically-backed alternative products.
Frequency Breathwork
Venture Round in 2021
Frequency Breathwork is a fitness platform offering live-streamed virtual breathwork classes. Its tool aims to reduce anxiety and depression, improve sleep and energy levels, enhance body function, and awaken states of consciousness.
Beckley Psytech
Venture Round in 2020
Founded in 2014, Beckley Psytech is a UK-based company dedicated to developing psychedelic medicines for treating mental health disorders. It focuses on rigorous scientific research and clinical-stage drug development, aiming to provide innovative treatments for conditions like depression and anxiety.
Alexander Shulgin Research Institute
Seed Round in 2020
The Alexander Shulgin Research Institute is a dedicated organization focused on the discovery, development, and education related to psychedelic substances. It aims to study and advance the understanding of these compounds for potential therapeutic applications.
Eleusis is a clinical stage life science company focused on harnessing the therapeutic potential of serotonin 2A receptor agonists, commonly known as psychedelics. The company aims to develop innovative psychedelic drug therapies that address unmet medical needs, particularly in the field of psychiatry and beyond. Eleusis is advancing a novel approach to transform psilocybin into a safe, effective, convenient, and affordable treatment option for depression. By doing so, the company seeks to provide healthcare providers and pharmaceutical companies with viable alternatives to conventional therapies, thereby broadening the scope of treatment options available to patients.
Cybin is a biopharmaceutical company dedicated to advancing research and development in psychedelic and medicinal mushrooms. It focuses on creating safe and effective therapeutics for mental health issues, with an emphasis on psilocybin-based products. The company is actively launching these products in jurisdictions where they are permitted and is engaged in clinical studies across North America and other regions. Through strategic partnerships with academic and institutional entities, Cybin seeks to develop novel compounds and delivery mechanisms, aiming to provide innovative treatments for various psychiatric and neurological conditions.
COMPASS Pathways
Series B in 2020
COMPASS Pathways is a UK-based mental health care company dedicated to accelerating patient access to innovative treatments for mental health challenges. The company focuses on developing psilocybin therapy, administered in conjunction with psychological support, for patients with treatment-resistant depression who have not responded to conventional treatments.
Eve Health Systems
Venture Round in 2020
Eve Health Systems is a data-driven health platform that helps patients to connect with their clinicians.