NorthSpring Capital Partners

Mesosil is a healthcare technology company specializing in the development of responsive antimicrobial materials designed to prevent infection at the interface between medical devices and tissues. Their primary focus is on dental applications, aiming to improve patient outcomes by reducing recurrent caries, detachment of dental restorations, and peri-implant infections. Mesosil's innovative technology offers long-lasting antimicrobial effects without disrupting practitioners' workflows.

Noa Therapeutics is a preclinical biotechnology company specializing in the development of innovative, multimodal treatments for immune diseases. The company's approach involves creating a single, non-steroidal, small molecule with adjustable potency, targeting three distinct therapeutic pathways to simplify and enhance patient care.

Oncoustics develops AI-enhanced ultrasound technology to analyze raw ultrasound signals from handheld devices, enabling rapid differentiation between healthy and diseased tissue. The approach generates novel acoustic biomarkers and supports non-invasive surveillance, diagnostics, and treatment monitoring for diseases with high unmet clinical needs. The company aims to improve clinical workflow productivity and has pursued regulatory pathways such as FDA Breakthrough Device designation for its OnX liver fibrosis detection, with 510(k) submission in progress, and plans for follow-on liver and other organ indications including prostate, kidney, breast and thyroid diseases and cancers.

Able Innovations develops robotic medical devices to improve patient transfer in healthcare. Its systems automate labor-intensive transfer tasks for frontline staff, enabling a single caregiver to move a patient laterally without physical effort. The technology aims to provide a safe, efficient, and dignified transfer experience for patients and caregivers while improving clinical throughput and reducing injuries among healthcare workers by removing manual strain from patient handling. The company focuses on enhancing care delivery and operational efficiency in clinical settings.

Rehabtronics specializes in developing medical devices aimed at aiding recovery from neurological issues such as stroke and spinal cord injury. Their product suite includes intermittent electrical stimulation technology designed to reduce pressure and enable patients to recover through simple, effective treatments.

Mesosil is a healthcare technology company specializing in the development of responsive antimicrobial materials designed to prevent infection at the interface between medical devices and tissues. Their primary focus is on dental applications, aiming to improve patient outcomes by reducing recurrent caries, detachment of dental restorations, and peri-implant infections. Mesosil's innovative technology offers long-lasting antimicrobial effects without disrupting practitioners' workflows.

FluidAI is a medical technology company focused on post-operative care, combining artificial intelligence with in-body data to improve patient monitoring. The company develops a smart catheter system that enables proactive post-operative care by detecting complications at onset and delivering critical health data to healthcare providers ahead of time.

DarwinAI Corp. is a Canadian company that specializes in artificial intelligence technology, particularly in the development of deep neural networks for enterprise applications. Founded in 2017 and based in Waterloo, the company offers GenSynth, a software platform designed for developers and data scientists to streamline the deep learning development process. GenSynth employs generative synthesis technology, allowing for the automatic creation of optimized, explainable AI models that meet specific performance criteria while ensuring transparency throughout the development stages. Additionally, DarwinAI has developed an AI-powered visual quality inspection system aimed at enhancing the PCBA manufacturing lifecycle. This system leverages specialized optics and advanced algorithms to detect defects in products, improving quality and consistency while reducing costs for manufacturers.

Forcen develops and manufactures force-sensing film for various industries, including surgical robotics, industrial robotics, and aerospace. Its film can be integrated into parts or assemblies of devices in these sectors, providing real-time force feedback. Founded in 2015, the company is headquartered in Toronto, Canada.

Workwolf is a Toronto-based startup that develops software to streamline hiring by filtering applicants and verifying resumes. Its CEO, Erik Simins, previously founded MAGNUS HRS, a staffing firm that now serves over 150 enterprise customers. Workwolf’s platform uses blockchain and AI to provide up‑to‑date background verification, producing detailed reports for employers and allowing candidates to create verified profiles. The solution reduces manual effort, shortens time‑to‑hire, and lowers the risk of mis‑hiring. The company has earned three global innovation awards and is preparing for a $4.5 million seed financing round.

Yourika Labs is a Canadian company based in Waterloo, established in 2016, that specializes in developing artificial intelligence-based platforms focused on enhancing online learning experiences. By leveraging extensive AI research from the University of Waterloo, the company has created its proprietary platform, ORBITS, which aims to improve remote learning for high school, university, and college students. The platform offers real-time personalized content for STEM subjects, identifying specific learning gaps and providing machine-powered tutoring that mimics human interaction. Additionally, it delivers valuable learning analytics to instructors, facilitating better engagement between students and teachers while optimizing time management in the educational process.

Forcen develops and manufactures force-sensing film for various industries, including surgical robotics, industrial robotics, and aerospace. Its film can be integrated into parts or assemblies of devices in these sectors, providing real-time force feedback. Founded in 2015, the company is headquartered in Toronto, Canada.

Underknown is a Toronto-based digital media company that focuses on producing short-form web series for social video platforms. The company specializes in creating data-driven content that simplifies complex subjects related to science, history, geography, and culture, aiming to educate and inspire creative thinking among its audience. Underknown's mission is to deliver fun and engaging educational material that enhances understanding of various topics, allowing viewers to explore hypothetical worlds and possibilities through its diverse range of documentary-style content. By leveraging multiple social media channels, Underknown effectively reaches a global audience with its innovative approach to digital storytelling.

CalendarHero is a company that specializes in developing a digital assistant application aimed at enhancing workplace productivity by minimizing distractions from operational tasks. Its automated virtual assistant streamlines various office functions, including meeting scheduling, workload management, and contact list organization. By setting reminders and storing essential background information, CalendarHero's platform enables enterprise managers to efficiently manage their time and resources, significantly improving overall productivity within organizations.

Nicoya Lifesciences Inc. is a Canadian company based in Kitchener that specializes in developing advanced sensor products for the biotechnology and pharmaceutical industries. Founded in 2012, Nicoya creates instruments designed to analyze biomolecular interactions, including proteins, antibodies, DNA, RNA, and small molecules. Their product lineup includes surface plasmon resonance (SPR) instruments, spectrophotometers, sensor chips, reagents, and accessories, as well as the OpenSPR, a personal label-free biomolecular analysis instrument. In addition to hardware, Nicoya offers software solutions for real-time kinetic analysis, instrument control, and optical peak tracking, enhancing the capabilities of their analytical tools.

SSIMWAVE Inc. is a software company specializing in video quality monitoring, diagnosis, and perceptual video compression, catering primarily to the media, communication, and entertainment industries. Founded in 2013 and based in Waterloo, Canada, SSIMWAVE develops innovative solutions such as the Video QoE Monitor and Video QoE Monitor Live, which assess and optimize video quality for on-demand and live broadcasts, respectively. Their Perceptual Stream Optimizer enhances video encoding processes to ensure consistent quality across various platforms, while Smart Video Streaming employs a quality-driven approach to adaptive streaming. The company's video experience automation platform integrates with existing workflows to provide actionable viewer experience data, enabling organizations, including leading Hollywood studios, to streamline quality assurance processes and effectively address video quality issues across all formats.

RYSE, formerly known as AXIS Labs, Inc., specializes in the automation of window shades through its innovative product, Gear. This device allows users to motorize and automate their existing window shades quickly and efficiently. Gear has been recognized as the 2017 Motorized Product of the Year by the Consumer Technology Association, highlighting its impact in the industry. The accompanying mobile application, compatible with both iOS and Android platforms, enables users to control and schedule their shades conveniently from their smartphones. Headquartered in Toronto, with additional offices in New York City and Shenzhen, RYSE aims to revolutionize the window shade market by integrating smart technology into everyday products.

Intellijoint Surgical Inc. is a Canadian medical device company founded in 2010 and headquartered in Waterloo, Canada. The company specializes in orthopedic surgical solutions, particularly with its flagship product, Intellijoint HIP. This miniaturized system aids orthopedic surgeons in the selection, positioning, and alignment of implants during hip replacement surgeries. Utilizing a combination of hardware and software, the device incorporates miniature optical sensors and microelectronics to provide quantitative intra-operative data on cup position, leg length, and offset. By offering this real-time feedback, Intellijoint HIP enhances surgical accuracy and improves patient outcomes while minimally impacting surgical workflow. The system is designed to be cost-effective and user-friendly, adding approximately 3-5 minutes to the surgical procedure. Intellijoint Surgical's innovations in orthopedic navigation have garnered recognition, including the North American Frost & Sullivan Enabling Technology Leadership Award in 2016.

KA Imaging designs and manufactures advanced X-ray detectors for medical and industrial applications. Its products include static detectors for pipe inspection, dual-energy detectors for baggage screening, dynamic detectors for engine inspection, and mammography detectors. The company's flagship product, Reveal, is a portable dual-energy subtraction X-ray detector cleared by the FDA, offering improved disease detection capabilities. Founded in 2015, KA Imaging is headquartered in Waterloo, Canada.

HTBASE is a developer of a composable operating system designed for medium and large enterprises, focusing on software-defined multicloud environments. The company offers a unique IT infrastructure solution that transforms compute, storage, and network resources into a flexible and scalable pool. This hardware-agnostic platform allows organizations to efficiently manage their technology operations and adapt to changing demands. By streamlining processes, HTBASE empowers IT teams to enhance service delivery and create greater value within their organizations. The company's innovative product offerings facilitate a more agile and cost-effective transition to cloud computing, enabling clients to optimize their IT capabilities.

Synergy Disc Replacement is a medical device company that develops and produces cervical disc implants intended to restore balance, range of motion, and alignment of the cervical spine.

Perimeter Medical Imaging AI is a medical technology company focused on revolutionizing cancer surgery through the development of ultra-high-resolution, real-time imaging tools. These advanced imaging solutions are designed to address significant unmet medical needs in the surgical field, enhancing the ability to detect and delineate cancerous tissues during procedures. By improving the accuracy of surgical interventions, Perimeter aims to optimize patient outcomes and contribute to more effective cancer treatment strategies.

Founded in 1996, directworx (formerly Pegasus Direct Mail Worx) offers state-of-art response technologies for direct mail and transactional mail campaigns encompassing all aspects of creative, data cleansing, dynamic imaging and delivery electronically or through postal services