Originate Ventures

Micro Interventional Devices, Inc., founded in 2010 and based in Newtown, Pennsylvania, is a medical device company specializing in disruptive technologies for percutaneous and minimally invasive structural heart repair procedures. The company designs and manufactures devices such as Permaseal, which facilitates transapical access and closure for catheter-based procedures, and Minimally Invasive Annuloplasty technology for tricuspid and mitral repair. Additionally, they offer Endovalve, a percutaneous mitral valve replacement system, and Permavalve, a percutaneous mitral valve with active fixation. Their proprietary technology focuses on soft-tissue anchoring and delivery devices, enabling off-pump procedures and transforming open surgical techniques into transcatheter procedures.

TB Biosciences, Inc. is an early stage development medical diagnostics company founded in June 2013 to develop a rapid point-of-care tuberculosis test that meets performance standards around the world. The goal of TB Biosciences is to commercialize a simple to operate and use tuberculosis test that replaces the 125 year old sputum smear test. The Company is using an array of patented peptides developed and exclusively licensed from the NYU School of Medicine.

ProtonMedia, Inc. specializes in e-learning solutions and virtual world technology for enterprises. The company is known for its flagship product, ProtoSphere, which creates a secure, private 3D environment designed for collaboration and learning. This platform supports various business applications, including e-learning, virtual meetings, and events, as well as scientific research and development, and collaborative efforts in sales and manufacturing that require rich data visualization. ProtonMedia serves a diverse clientele across sectors such as pharmaceuticals, medical devices, financial services, and technology, with a global reach. Founded in 1998, the company is headquartered in Lansdale, Pennsylvania.

BA Insight specializes in integrated search technologies that enhance the capabilities of Microsoft SharePoint and FAST Search for organizations. Founded in 2004 and based in New York City, the company offers its flagship products, Longitude Search and Longitude Connector, which extend enterprise search functionalities across various systems, including CRM, ERP, and ECM. These tools provide rich document previews and assembly features, enabling knowledge workers to efficiently act on search results. BA Insight's solutions have been adopted by numerous clients, including Fortune 500 companies and government agencies, to optimize information access and improve productivity. The company operates globally, supported by a network of certified partners and resellers, and is recognized as a Managed Microsoft Partner.

Holganix, Inc. is a manufacturer of plant-based bio-stimulant soil supplements aimed at enhancing soil health and promoting sustainable plant growth. Founded in 2010 and headquartered in Glen Mills, Pennsylvania, the company offers a range of products including tree and shrub solutions, golf course treatments, agriculture products, and flower programs. A key offering is Holganix Bio 800+, which contains beneficial microorganisms, microbe food, and nutrient enhancers that optimize soil conditions. Holganix's products are designed to reduce fertilizer use by up to 90%, thereby lowering costs for landscape and lawn care companies while minimizing environmental impact. The company sells its products through distributors in the United States and also offers online sales.

Micro Interventional Devices, Inc., founded in 2010 and based in Newtown, Pennsylvania, is a medical device company specializing in disruptive technologies for percutaneous and minimally invasive structural heart repair procedures. The company designs and manufactures devices such as Permaseal, which facilitates transapical access and closure for catheter-based procedures, and Minimally Invasive Annuloplasty technology for tricuspid and mitral repair. Additionally, they offer Endovalve, a percutaneous mitral valve replacement system, and Permavalve, a percutaneous mitral valve with active fixation. Their proprietary technology focuses on soft-tissue anchoring and delivery devices, enabling off-pump procedures and transforming open surgical techniques into transcatheter procedures.

FSAstore.com, Inc. is an online retail platform specializing in products eligible for Flexible Spending Accounts (FSA) and Health Savings Accounts (HSA) in the United States. Founded in 2010 and based in New York, the website serves as a comprehensive resource for consumers looking to purchase tax-free medical items. It offers a wide range of products, including personal care items, baby health products, home medical supplies, cold and allergy remedies, vitamins, and travel essentials. By exclusively stocking FSA and HSA-eligible products, FSAstore.com simplifies the shopping experience, removing the uncertainty regarding reimbursement. Customers benefit from a streamlined purchasing process that does not require receipt submission when using their debit cards. The platform provides 24/7 customer service, quick order processing, and free shipping on purchases over $50, catering to the needs of account holders seeking accessible health solutions.

CMP.LY provides social media measurement, social media marketing optimization, social media disclosures, social disclosure standardization, social media risk mitigation, and social media management.

ClickPay is a company focused on revolutionizing the real estate payment process by providing a comprehensive billing and payment platform. It aims to modernize and automate how businesses in the real estate sector bill, collect, and manage payments. The platform supports various payment methods, including checks, e-checks, credit, and debit cards, allowing real estate enterprises to enhance operational efficiency and improve resident satisfaction. By redefining receivables, ClickPay plays a crucial role in streamlining financial transactions within the trillion-dollar real estate industry.

ProtonMedia, Inc. specializes in e-learning solutions and virtual world technology for enterprises. The company is known for its flagship product, ProtoSphere, which creates a secure, private 3D environment designed for collaboration and learning. This platform supports various business applications, including e-learning, virtual meetings, and events, as well as scientific research and development, and collaborative efforts in sales and manufacturing that require rich data visualization. ProtonMedia serves a diverse clientele across sectors such as pharmaceuticals, medical devices, financial services, and technology, with a global reach. Founded in 1998, the company is headquartered in Lansdale, Pennsylvania.

Tabula Rasa Healthcare, formerly known as CareKinesis, specializes in state-of-the-art medication management solutions that leverage technology, science, and services to enhance the quality of care, reduce costs, and mitigate risks associated with ineffective medication plans. Their innovative approach aims to optimize medication therapy for improved patient outcomes.

ThermalTherapeutic Systems was founded in June, 2006 by a team of highly respected experts in the field of hyperthermic perfusion technology, medical device manufacturing, molecular diagnostics and technology commercialization.

RightsFlow is a technology-driven provider of mechanical licensing and royalty accounting services for the music industry, catering to online music companies, record labels, distributors, artists, and songwriters. The company specializes in obtaining various licenses, including mechanical, digital downloads, and ringtone rights, while also offering royalty accounting and payment services. RightsFlow's advanced technology enables efficient song identification and ensures transparency for both licensees and licensors. With a database of over 30 million songs, the firm can quickly license content, manage accounting, and facilitate royalty payments, ensuring that rights-holders receive compensation for the use of their works. Acquired by Google in 2011, RightsFlow is now integrated into YouTube, where it contributes to simplifying music licensing, content identification, and payment processes for songwriters and publishers worldwide.

ProtonMedia, Inc. specializes in e-learning solutions and virtual world technology for enterprises. The company is known for its flagship product, ProtoSphere, which creates a secure, private 3D environment designed for collaboration and learning. This platform supports various business applications, including e-learning, virtual meetings, and events, as well as scientific research and development, and collaborative efforts in sales and manufacturing that require rich data visualization. ProtonMedia serves a diverse clientele across sectors such as pharmaceuticals, medical devices, financial services, and technology, with a global reach. Founded in 1998, the company is headquartered in Lansdale, Pennsylvania.

South49 Solutions, Inc. is a company that develops workforce management platforms, offering web-based applications designed to streamline the scheduling and status reporting for field employees. Its primary products include Natural Insight, which caters to the retail merchandising and field marketing sectors, and Capango, focused on broader workforce management needs. Incorporated in 2008 and based in Sterling, Virginia, South49 Solutions serves customers globally, providing tools that enhance operational efficiency for businesses managing field operations.

Nayatek LLC, established in 2006, is a global provider of enterprise Information Management solutions. The company specializes in offering Content Archiving, EDiscovery, Storage Management, and Compliance services to help organizations secure, manage, and protect their messaging and electronic document resources. By providing robust procedures tailored to industry regulations, Nayatek aims to ensure the security, integrity, and privacy of its clients' data.

Adhezion Biomedical, LLC is a medical device company that develops, manufactures, and commercializes cyanoacrylate-based adhesives and infection prevention products. Founded in 2001 and headquartered in Wyomissing, Pennsylvania, the company offers a range of solutions including SurgiSeal, which is used to hold skin edges together after surgical incisions, and FloraSeal, a sterile microbial sealant applied prior to surgical incisions. In addition to these products, Adhezion Biomedical provides various surgical and wound management solutions, along with animal health products. The company's focus on innovative cyanoacrylate technologies aims to enhance wound closure and care across multiple surgical and medical disciplines, supporting healthcare practitioners in delivering effective patient care.