Originate Ventures

Micro Interventional Devices, Inc., founded in 2010 and based in Newtown, Pennsylvania, is a medical device company specializing in disruptive technologies for percutaneous and minimally invasive structural heart repair procedures. The company designs and manufactures devices such as Permaseal, which facilitates transapical access and closure for catheter-based procedures, and Minimally Invasive Annuloplasty technology for tricuspid and mitral repair. Additionally, they offer Endovalve, a percutaneous mitral valve replacement system, and Permavalve, a percutaneous mitral valve with active fixation. Their proprietary technology focuses on soft-tissue anchoring and delivery devices, enabling off-pump procedures and transforming open surgical techniques into transcatheter procedures.

TB Biosciences, Inc. is an early stage development medical diagnostics company founded in June 2013 to develop a rapid point-of-care tuberculosis test that meets performance standards around the world. The goal of TB Biosciences is to commercialize a simple to operate and use tuberculosis test that replaces the 125 year old sputum smear test. The Company is using an array of patented peptides developed and exclusively licensed from the NYU School of Medicine.

ProtonMedia, Inc. is a provider of e-learning and virtual collaboration solutions, headquartered in Lansdale, Pennsylvania. Founded in 1998, the company specializes in developing ProtoSphere, a business collaboration software that creates a secure, three-dimensional environment tailored for various applications such as e-learning, virtual meetings, and collaborative events. This platform facilitates scientific research, development projects, and sales and manufacturing collaborations, all enhanced by rich data visualization. ProtonMedia serves a diverse range of clients across industries, including pharmaceuticals, medical devices, financial services, and technology, providing innovative tools to enhance organizational communication and learning experiences.

BA Insight is a technology company specializing in integrated search solutions that enhance the capabilities of Microsoft SharePoint and FAST Search within enterprises. Established in 2004 and headquartered in New York City, the company offers products like Longitude Search and Longitude Connector, which extend search functionalities across various systems, including CRM, ERP, and content management platforms. These tools provide advanced document preview and assembly features, enabling knowledge workers to act on search results more efficiently. BA Insight serves a diverse clientele, including Fortune 500 companies and government agencies, and has a global presence with sales offices and research facilities in the United States and Europe. The company's AI-driven technology combines machine learning and cognitive computing to facilitate cognitive search services, ultimately improving information retrieval and team productivity. As a Managed Microsoft Partner, BA Insight supports organizations in maximizing their information assets while enhancing overall user productivity.

Holganix, Inc. is a manufacturer of plant-based bio-stimulant soil supplements designed to enhance soil health and promote sustainable growth in plants. Founded in 2010 and headquartered in Glen Mills, Pennsylvania, the company produces a range of products, including those for trees, shrubs, golf courses, and agriculture, as well as granular offerings. A key product, Holganix Bio 800+, contains beneficial microorganisms, microbe food, and nutrient enhancers that optimize soil conditions. By utilizing natural microorganisms, Holganix enables users to significantly reduce fertilizer usage—by as much as 90%—while achieving healthier and more vibrant lawns and trees. The company's products are distributed throughout the United States and are available for purchase online, reflecting its commitment to providing cost-effective and environmentally friendly solutions for landscape and lawn care professionals.

Micro Interventional Devices, Inc., founded in 2010 and based in Newtown, Pennsylvania, is a medical device company specializing in disruptive technologies for percutaneous and minimally invasive structural heart repair procedures. The company designs and manufactures devices such as Permaseal, which facilitates transapical access and closure for catheter-based procedures, and Minimally Invasive Annuloplasty technology for tricuspid and mitral repair. Additionally, they offer Endovalve, a percutaneous mitral valve replacement system, and Permavalve, a percutaneous mitral valve with active fixation. Their proprietary technology focuses on soft-tissue anchoring and delivery devices, enabling off-pump procedures and transforming open surgical techniques into transcatheter procedures.

FSAstore.com, Inc. is an online retail platform specializing in products eligible for Flexible Spending Accounts (FSA) and Health Savings Accounts (HSA) in the United States. Founded in 2010 and based in New York, the website serves as a comprehensive resource for consumers looking to purchase tax-free medical items. It offers a wide range of products, including personal care items, baby health products, home medical supplies, cold and allergy remedies, vitamins, and travel essentials. By exclusively stocking FSA and HSA-eligible products, FSAstore.com simplifies the shopping experience, removing the uncertainty regarding reimbursement. Customers benefit from a streamlined purchasing process that does not require receipt submission when using their debit cards. The platform provides 24/7 customer service, quick order processing, and free shipping on purchases over $50, catering to the needs of account holders seeking accessible health solutions.

CMP.LY provides social media measurement, social media marketing optimization, social media disclosures, social disclosure standardization, social media risk mitigation, and social media management.

ClickPay is a company focused on revolutionizing the real estate payments sector by modernizing and automating billing and collection processes. Its platform provides integrated payment services that support a variety of payment methods, including checks, e-checks, credit, and debit cards. By streamlining receivables management, ClickPay enables real estate enterprises to enhance operational efficiencies and improve resident satisfaction. The company's innovative approach aims to reshape the way payments are processed within the trillion-dollar real estate industry.

ProtonMedia, Inc. is a provider of e-learning and virtual collaboration solutions, headquartered in Lansdale, Pennsylvania. Founded in 1998, the company specializes in developing ProtoSphere, a business collaboration software that creates a secure, three-dimensional environment tailored for various applications such as e-learning, virtual meetings, and collaborative events. This platform facilitates scientific research, development projects, and sales and manufacturing collaborations, all enhanced by rich data visualization. ProtonMedia serves a diverse range of clients across industries, including pharmaceuticals, medical devices, financial services, and technology, providing innovative tools to enhance organizational communication and learning experiences.

Tabula Rasa Healthcare, formerly known as CareKinesis, specializes in state-of-the-art medication management solutions that leverage technology, science, and services to enhance the quality of care, reduce costs, and mitigate risks associated with ineffective medication plans. Their innovative approach aims to optimize medication therapy for improved patient outcomes.

ThermalTherapeutic Systems was founded in June, 2006 by a team of highly respected experts in the field of hyperthermic perfusion technology, medical device manufacturing, molecular diagnostics and technology commercialization.

RightsFlow is a technology-driven provider of mechanical licensing and royalty accounting services for the music industry, catering to online music companies, record labels, distributors, artists, and songwriters. The company specializes in securing various types of licenses, including bulk mechanical, digital downloads, physical, and ringtone licenses, as well as rights for interactive streaming and limited downloads. RightsFlow's proprietary technology and extensive database of over 30 million songs enable efficient licensing, accurate accounting, and prompt royalty payments, ensuring that rights-holders receive proper compensation for their work. Since its acquisition by Google in 2011, RightsFlow has become an integral part of YouTube, working to streamline music licensing and enhance content identification, accounting, and payment processes for songwriters and publishers on a global scale.

ProtonMedia, Inc. is a provider of e-learning and virtual collaboration solutions, headquartered in Lansdale, Pennsylvania. Founded in 1998, the company specializes in developing ProtoSphere, a business collaboration software that creates a secure, three-dimensional environment tailored for various applications such as e-learning, virtual meetings, and collaborative events. This platform facilitates scientific research, development projects, and sales and manufacturing collaborations, all enhanced by rich data visualization. ProtonMedia serves a diverse range of clients across industries, including pharmaceuticals, medical devices, financial services, and technology, providing innovative tools to enhance organizational communication and learning experiences.

South49 Solutions, Inc. is a company that develops workforce management platforms, offering web-based applications designed to streamline the scheduling and status reporting for field employees. Its primary products include Natural Insight, which caters to the retail merchandising and field marketing sectors, and Capango, focused on broader workforce management needs. Incorporated in 2008 and based in Sterling, Virginia, South49 Solutions serves customers globally, providing tools that enhance operational efficiency for businesses managing field operations.

Nayatek LLC, established in 2006, is a global provider of enterprise Information Management solutions. The company specializes in offering Content Archiving, EDiscovery, Storage Management, and Compliance services to help organizations secure, manage, and protect their messaging and electronic document resources. By providing robust procedures tailored to industry regulations, Nayatek aims to ensure the security, integrity, and privacy of its clients' data.

Adhezion Biomedical is a privately-held medical device company based in Wyomissing, Pennsylvania. Founded in 2001, the company specializes in developing, manufacturing, and commercializing cyanoacrylate-based adhesive and infection prevention products. Their portfolio includes SurgiSeal for wound closure from surgical incisions and punctures, FloraSeal microbial sealant for use after skin preparations prior to surgery, and various animal health products. Adhezion Biomedical also offers solutions for surgical procedures, wound management, and infection prevention. The company was previously known as Spartan Medical Products before changing its name in 2008.