Arzeda is a protein design company that creates and manufactures proteins and enzymes for pharmaceuticals and industrial chemicals. The company provides intelligent protein design technology, combining physics-based protein design and AI algorithms to develop, validate, and manufacture new designer proteins and enzymes.
Kenota Health develops next-generation rapid point-of-care system intended to be used for allergy testing in humans. Kenota's diagnostic tools are safe, simple, and offer a cheaper alternative to allergy testing using a thorough non-invasive technology, enabling physicians to improve patient outcomes.
A-Alpha Bio is a provider of cell-based tools for quantitative and high-throughput measurements of protein interactions, accelerating target discovery, library screening, and preclinical drug characterization. A-Alpha Bio utilizes its proprietary AlphaSeq technology to map protein-protein interactions at a high scale and resolution. This technology can identify and quantify interactions between thousands of protein pairs simultaneously. By providing detailed maps of protein interactions, A-Alpha Bio aids in the identification of potential drug targets and the understanding of disease mechanisms. This can significantly streamline the process of discovering new therapeutics. A-Alpha Bio is a team of synthetic biologists, structural biologists, and next-generation sequencing experts who have come together to remove this industry-wide bottleneck.
GRO Biosciences is leveraging breakthrough technologies from computational protein design and synthetic biology to develop best-in-class protein therapeutics with enhanced properties. The company has established multiple genomically recoded strains of bacteria that can incorporate non-standard amino acids into proteins to confer increased potency, stability, and targeted delivery. GRO Biosciences is applying its technology platform to develop improved protein therapeutics for diabetes, growth disorders, and autoimmunity.
uBiome provides smart gut tests, clinical microbiome testing, healthcare services, citizen science, healthful probiotic cultures, discoveries, and medical services.
Verge Genomics transforms drug discovery with artificial intelligence. Verge was founded by a unique combination of the field's top machine learning experts and seasoned neuroscience drug developers. Together, they share the vision that exponential advances in computational genomics combined with new insights into neuroscience has created a breakthrough opportunity to discover drugs that dramatically improve the lives of patients suffering from neurodegenerative disease.
Lygos is providing biotechnology solutions for today’s renewable chemical challenges. They engineer microbes to convert sugars into high-value, industrial chemicals, targeting compounds where biological production is cost-advantaged over petrochemical production. The company's throughput screening and strain construction facilitate the rapid optimization of pathways to convert cheap and renewable feedstock to high-value chemicals. Founded in 2011, Lygos is headquartered in Berkeley, California.
Catalog is a developer of a data conversion and storage platform used to offer the next generation of digital data archives and computation. Its platform facilitates the encoding of data and information into DNA format and makes it economically attractive to use DNA as the major medium for long-term archival of data that enables customers to store digital information in DNA molecules. It brings cutting-edge synthetic biology technologies to the world of information storage and computation. The company was founded in 2016 and is headquartered in Boston, Massachusetts.
NuMat Technologies builts an Operating System for the commercialization of programmable chemistries. It is creating the future of precision engineering by designing and building molecularly-programmed systems that unlock paradigm shifts in resource creation and use. The company's expertise lies in the design and integration of MOFs into next-generation storage, separation, and purification systems. In doing so, NuMat enables previously unachievable form factors, performance and cost-advantaged production economics. NuMat provides a total solutions platform for product commercialization, pairing world-class material discovery software with application development and manufacturing expertise.
Aria Pharmaceuticals is a preclinical-stage pharmaceutical company discovering and developing novel small molecule therapies for complex and hard-to-treat diseases. Too many patients today are in need of breakthrough treatments across many complicated diseases – they can't wait. That's why at Aria, we have redefined the drug discovery approach, saving years in the process and increasing success rates 30 times higher than traditional methods. At Aria, we've shown promise across a diverse range of therapeutic areas with the ability to address over 1,000 diseases.
GRO Biosciences is leveraging breakthrough technologies from computational protein design and synthetic biology to develop best-in-class protein therapeutics with enhanced properties. The company has established multiple genomically recoded strains of bacteria that can incorporate non-standard amino acids into proteins to confer increased potency, stability, and targeted delivery. GRO Biosciences is applying its technology platform to develop improved protein therapeutics for diabetes, growth disorders, and autoimmunity.
Founded in 2017, 3T Biosciences is an immunotherapy company headquartered in Menlo Park, California.
Arzeda is a protein design company that creates and manufactures proteins and enzymes for pharmaceuticals and industrial chemicals. The company provides intelligent protein design technology, combining physics-based protein design and AI algorithms to develop, validate, and manufacture new designer proteins and enzymes.
Catalog is a developer of a data conversion and storage platform used to offer the next generation of digital data archives and computation. Its platform facilitates the encoding of data and information into DNA format and makes it economically attractive to use DNA as the major medium for long-term archival of data that enables customers to store digital information in DNA molecules. It brings cutting-edge synthetic biology technologies to the world of information storage and computation. The company was founded in 2016 and is headquartered in Boston, Massachusetts.
Synthego is a genome engineering company that enables the acceleration of life science research and development in the pursuit of improved human health. The company leverages machine learning, automation, and gene editing to build platforms for science at scale. With its foundations in engineering disciplines, the company’s full-stack platform vertically integrates proprietary hardware, software, bioinformatics, chemistries, and molecular biology to advance both basic research and therapeutic development programs. By providing both commercial and academic researchers and therapeutic developers with unprecedented access to cutting-edge genome engineering, Synthego is at the forefront of innovation, accelerating the development of truly engineered biology. The company was founded in 2012 and is based in Redwood City, California.
Lygos is providing biotechnology solutions for today’s renewable chemical challenges. They engineer microbes to convert sugars into high-value, industrial chemicals, targeting compounds where biological production is cost-advantaged over petrochemical production. The company's throughput screening and strain construction facilitate the rapid optimization of pathways to convert cheap and renewable feedstock to high-value chemicals. Founded in 2011, Lygos is headquartered in Berkeley, California.
Prospect Bio is a synthetic biology company that specializes in building biosensors (living cells) that can measure chemicals. Biosensors are powerful measurement tools which can perform highly complex testing tasks while being near costless to manufacture, field deployable, and massively scalable. As such, Prospect's work generally focusses on taking broken testing processes - often ones that rely on expensive ($0.5M+), slow, and lab-bound equipment - and replacing them with an affordable, scalable, and on-site biosensor based solutions. The need for improved testing solutions is being driven on a variety of fronts, including growing regulation, increased QC, and concerns about supply chain assurance. This problem set affects numerous industries, as shown by Prospect's diverse partner list which includes one of the three largest wine companies in the the world, a leading California-based Ag company, a prenatal diagnostics maker, and Ginkgo Bioworks. Prospect Bio has raised $2.8M, and is supported by investors including Illumina, Viking Capital, Stanford-StartX, Digital Sky Technologies, and Rising Tide Fund.
Emulate is a privately held company that creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health.
Their founding team possesses a unique combination of expertise in synthetic biology, environmental genomics, and bioinformatics. They founded MetaMixis to enable the emergence of the bioeconomy by revolutionizing enzyme and pathway discovery. Along the way, they've brought in a world-class Board who they enjoy learning from every day.
Kenota Health develops next-generation rapid point-of-care system intended to be used for allergy testing in humans. Kenota's diagnostic tools are safe, simple, and offer a cheaper alternative to allergy testing using a thorough non-invasive technology, enabling physicians to improve patient outcomes.
Kenota Health develops next-generation rapid point-of-care system intended to be used for allergy testing in humans. Kenota's diagnostic tools are safe, simple, and offer a cheaper alternative to allergy testing using a thorough non-invasive technology, enabling physicians to improve patient outcomes.
NuMat Technologies builts an Operating System for the commercialization of programmable chemistries. It is creating the future of precision engineering by designing and building molecularly-programmed systems that unlock paradigm shifts in resource creation and use. The company's expertise lies in the design and integration of MOFs into next-generation storage, separation, and purification systems. In doing so, NuMat enables previously unachievable form factors, performance and cost-advantaged production economics. NuMat provides a total solutions platform for product commercialization, pairing world-class material discovery software with application development and manufacturing expertise.
Non Equity Assistance in 2016
Mozio is an airport ground transportation search engine. We help you travel that final mile from the airport to your final destination. Mozio originated out of founder David Litwak's travels, where he was constantly frustrated by flying into new destinations and realizing he had no clue how to actually get into the city. Mozio aggregates all the local taxis, limos, public transit, shared-ride shuttles, airporters, rideshare etc. to help you navigate all the local options and make sure you get the best deal. We have raised a small seed round from Amidzad Partners, and a few angels, one of whom is the Chairman of the Board @ Orbitz. We are super excited to make this dream a reality!
3Scan is turning tissue into bits by building robotic microscopy tools and software for large-scale sample analysis and 3D visualizations. Many diseases emerge only at a tissue level, such as cancer, heart disease, lung disease, stroke, Alzheimer's, and diabetes. 3Scan enables higher throughput, greater quantification, and broader image analysis than what is currently possible with traditional histopathology. 3Scan's data-driven approach is expanding our understanding of tissue biology and will lead to the discovery of new diagnostics and therapeutics. The company was founded in 2011 and is headquartered in San Francisco, California.
Elysium Health offers health products built with science such as dietary supplements and anti-aging drugs. It seeks to solve challenges in health with science, to help people live healthier and longer lives. It works directly with the scientists, clinicians, and health professionals around the world to identify and develop the natural compounds. Its product is a proprietary formulation of two ingredients designed to support long-term well-being at the cellular level.
Planetary Resources is bringing the natural resources of space within humanity’s economic sphere of influence, propelling us into the 21st century and beyond…today. Asteroids will play a key role in the development of a space economy and be the main driver in allowing humanity to become a flourishing multi-planetary species. Water from asteroids will fuel the in-space economy and habitation, by creating rocket fuel and consumable water from space, for space.
Nanoly is engaged in the development of a polymer that enables vaccines and therapeutics to survive without refrigeration. It was founded in 2012 and is based in Boulder, Colorado.
Human Longevity (HLI) is the genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived. HLI combines the largest database of genomic and phenotypic data with machine learning to drive discoveries and revolutionize the practice of medicine. Its business areas include the HLI Health Nucleus, a genomic powered clinical research center that uses whole-genome sequence analysis, advanced clinical imaging, and innovative machine learning, along with curated personal health information to deliver the most complete picture of individual health; HLIQ Whole Genome and HLIQ Oncology. It was founded in 2013 and is headquartered in San Diego, California.
Emulate is a privately held company that creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health.
Pivot Bio is improving and using a deep understanding of the microbiome to advance crop nutrition. They believe that microbes can deliver nutrients, protect against pests, and improve crop quality better than chemical fertilizers and pesticides. They leverage engineering principles and data science to map the dynamics of the plant microbiome and evolve beneficial traits. Their team thrives on collaboration and communication as they seek to create revolutionary fertilizers that transform food supply and improves the planet. Pivot Bio's proprietary ON Technology harnesses the power of naturally occurring microbes to provide more nutrients to crops. It’s a smart, sustainable way for farmers to improve yield as they work to help feed the world’s growing population. Their current efforts are focused on enabling microbes to fix and supply more nitrogen to corn. Pivot Bio was founded in 2010 and is headquartered in Berkeley, California, United States.
Viv Labs, Inc. is a technology company based in San Jose, California, specializing in artificial intelligence interfaces that facilitate interaction with various devices, services, and platforms. Founded in 2012 and originally known as Six Five Labs, Viv creates a global platform that enables developers to build intelligent conversational interfaces. This universal digital assistant is designed to handle a wide array of spoken requests by integrating with multiple services, allowing users to engage seamlessly with technology. Since May 2014, Viv has operated as a subsidiary of Samsung Research America, continuing its mission to enhance user interaction through advanced AI capabilities.
Verge Genomics transforms drug discovery with artificial intelligence. Verge was founded by a unique combination of the field's top machine learning experts and seasoned neuroscience drug developers. Together, they share the vision that exponential advances in computational genomics combined with new insights into neuroscience has created a breakthrough opportunity to discover drugs that dramatically improve the lives of patients suffering from neurodegenerative disease.
Lucira Health is a medical technology company focused on the development and commercialization of transformative and innovative infectious disease test kits. Lucira has developed a testing platform that produces centralized-laboratory-accurate molecular testing in a single-use and consumer-friendly test kit that is powered by two AA batteries and fits in the palm of a hand.
Ginkgo Bioworks is a biotechnology firm. It is a developer of biological engineering products and custom microbes across multiple markets. It designs, engineer, develops, tests, and licenses organisms. It discovers molecules in flavors, sweeteners, cosmetic ingredients, crop treatments, and pharmaceuticals. It also provides probiotic bacteria to protect the body from dangerous infections, and it generates libraries of molecules. It serves cultured ingredients, carbon mitigation, probiotics, and natural product discovery markets.
Atomwise is a preclinical pharma company revolutionizing how drugs are discovered with AI. We invented the use of deep learning for structure-based drug discovery, today developing a pipeline of small-molecule drug candidates advancing into preclinical studies. Our AtomNet® technology has been used to unlock more undruggable targets than any other AI drug discovery platform. We are tackling over 600 unique disease targets with more than 250 partners around the world, including leading pharmaceutical, agrochemical, and emerging biotechnology companies. Atomwise has raised over $174 million from leading venture capital firms to advance our mission to make better medicines, faster. Learn more at atomwise.com, or connect on Twitter and LinkedIn.
Emerald was founded in 2010 by two scientists and life-long friends from Philadelphia with a singular vision of how a biotechnology company should run. Frustrated by the continual deceleration of innovation and the exponentially increasing R&D costs in the pharmaceutical sector, Emerald models itself after the legendary start-up companies of the mid-20th century that built the core technologies underlying the meteoric rise of the semiconductor industry. The team places as much focus on building tools around how scientific research is conducted as they do on their proprietary anti-viral therapies. In this way, Emerald is striving to bring a Moore’s law-like acceleration to life sciences innovation.
Tempo Automation is transforming the way companies innovate and bring new electronic products to market. Tempo’s breakthrough, software-automated PCBA manufacturing platform delivers unprecedented speed, quality and transparency at the most critical time in a product’s lifecycle – prototype through new product introduction – when fast iteration and time to market are imperatives. Customers who count on Tempo Automation for this strategic advantage include the leading innovators in aerospace, medical technology, semiconductor, industrial technology, automotive and other key industries.
Eat Just offers a plant-based egg substitute intended to provide healthy and nutritional food alternatives. It applies innovative science and technology to create healthier, more sustainable foods the key ingredient is protein from the mung bean and it is cholesterol-free, non-GMO, and packed with as much protein as many animal proteins and while it cooks and tastes like eggs. Its ingredients use less water and less land, and emit less CO2e than conventional animal sources, enabling customers to prepare their food items with the required nutrients and protein of an egg. It was founded by Josh Balk and Josh Tetrick in San Francisco, California in 2011.
Plethora provides CNC machining services. They create manufacturing systems that turn customer designs into custom parts using robotics and in-house software. They analyze CAD models to provide design feedback for manufacturing from within the client's CAD software.
Miroculus is a hands off sample-to-answer solution for molecular testing. Miroculus delivers assay flexibility and automation capacity in an affordable digital microfluidics platform, which enables seamless workflow integration from novel molecular protocols to data analytics.
uBiome provides smart gut tests, clinical microbiome testing, healthcare services, citizen science, healthful probiotic cultures, discoveries, and medical services.
uBiome provides smart gut tests, clinical microbiome testing, healthcare services, citizen science, healthful probiotic cultures, discoveries, and medical services.
Vicarious is an artificial intelligence company that uses the computational principles of the brain to develop general intelligence for robots. The company was founded in 2010 by Dr. Dileep George and D. Scott Phoenix.
Human Longevity (HLI) is the genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived. HLI combines the largest database of genomic and phenotypic data with machine learning to drive discoveries and revolutionize the practice of medicine. Its business areas include the HLI Health Nucleus, a genomic powered clinical research center that uses whole-genome sequence analysis, advanced clinical imaging, and innovative machine learning, along with curated personal health information to deliver the most complete picture of individual health; HLIQ Whole Genome and HLIQ Oncology. It was founded in 2013 and is headquartered in San Diego, California.
Cleversafe’s breakthrough technology provides data storage for the hyperscale world. As unstructured content continues to grow at 60-80 percent per year — from videos and photos to genomic sequencing data to regulated reporting in financial services — enterprises and service providers are looking for a data storage solution for multi-petabyte environments. Only Cleversafe delivers proven scalability combined with 80 percent or more improvement in economic efficiency, zero touch security, and simplicity that allows organizations to get applications off the ground quickly and scale them for the demand they expect. The hyperscale world relies on hyperscale data storage from Cleversafe.
LightSail Energy develops breakthrough, high efficiency energy storage systems using compressed air.