Oxford Science Enterprises

Oxford Science Enterprises is a venture firm based in Oxford, United Kingdom, established in 2015 in partnership with the University of Oxford. The firm focuses on building and investing in companies that develop fundamental technologies aimed at addressing significant global challenges. Its investment areas include life sciences, healthcare, artificial intelligence, software, and deep tech, targeting issues such as nuclear fusion, quantum computing, and the development of treatments for infectious diseases. By leveraging its extensive experience and a robust network of investors, entrepreneurs, and sector experts, Oxford Science Enterprises aims to foster a world-class technology ecosystem and support the growth of innovative science-based businesses.

Sally Dewhurst Ph.D

Principal, Life Sciences

Nicholas Dixon-Clegg

Principal

Sam Harman

Senior investment associate

James Wong

Principal, Life Sciences

Alexis Zervoglos

Senior Partner, Technology

George Todd

Senior Associate, Deep Tech

Katya Smirnyagina Ph.D

Senior Partner, Life Sciences

Liliane Chamas Ph.D

Principal, Health Tech

Oliver Mahony Ph.D

Principal

160 past transactions

Porpoise Power

Pre Seed Round in 2025
Porpoise Power develops a tidal energy system using oscillating hydrofoil technology inspired by dolphin swimming mechanics.

Mode Labs

Pre Seed Round in 2025
Mode Labs provide robust, continuous, and remote real-time chemical sensors.

Seloxium

Seed Round in 2025
Seloxium is a company focused on assisting mining, refining, and industrial sectors in achieving their environmental, social, and governance (ESG) objectives by transforming wastewater into profitable and sustainable resources. Utilizing advanced selective flocculation technology, Seloxium enables the extraction of valuable metals from wastewater and mine tailings, offering an innovative approach to metal recovery. This technology allows businesses to obtain high-purity metals from their waste streams while minimizing their carbon footprint and preventing harmful metals from entering the environment. By providing an effective solution for recycling and refining processes, Seloxium supports companies in enhancing their sustainability practices and improving their overall environmental impact.

Alloyed

Series B in 2025
Alloyed, established in 2017 and based in Begbroke, United Kingdom, specializes in alloy design and optimization through its proprietary software, Alloys-by-Design. The company focuses on researching and developing advanced alloy methods, along with the manufacture and licensing of proprietary alloys, alloy powders, and components. Alloyed serves a diverse array of sectors, including aerospace, automotive, defense, medical devices, energy, and consumer goods. By leveraging data and advanced physical models, Alloyed's platform simulates the performance of millions of potential alloys simultaneously, facilitating optimization across various performance, manufacturing, and economic parameters. This approach enables clients to enhance their applications in critical industries.

Mixergy

Venture Round in 2025
Mixergy Ltd, founded in 2014 and based in Cassington, United Kingdom, specializes in the development of energy storage equipment, particularly hot water tanks. The company aims to provide cost-effective solutions that enhance energy efficiency and support the integration of renewable energy sources. By optimizing the use of solar photovoltaic systems and heat pumps, Mixergy tanks contribute to grid balancing, promoting greater utilization of renewable power generation.

Salience Labs

Series A in 2025
Salience Labs specializes in developing hybrid photonic-electronic chips tailored for artificial intelligence applications. Originating from extensive research at the University of Oxford and the University of Münster, the company focuses on silicon photonics to meet the increasing demands of AI workloads in data center infrastructure. Its flagship product, an optical switch, enables all-optical networking between computing nodes, effectively addressing data movement bottlenecks. By utilizing photons instead of electrons for data processing, Salience Labs' technology significantly reduces power consumption while enhancing processing speeds. This innovative approach aims to transform the hardware landscape necessary for maximizing AI capabilities, providing low-latency, high-bandwidth networking that accelerates job completion and lowers operational costs.

Neu Health

Seed Round in 2025
Neu Health develops a smartphone-based clinical platform designed to deliver personalized care for individuals with Parkinson's disease and dementia. Utilizing cutting-edge digital technologies and artificial intelligence, the platform monitors and interprets digital indicators of clinically relevant symptoms. This approach aims to enhance condition management, alleviate the workload on clinicians, and ultimately improve patient outcomes. By enabling clinicians and caregivers to provide more efficient and effective care, Neu Health addresses the growing challenges faced by those managing these complex neurological conditions.

Fluorok

Seed Round in 2024
FluoRok is transforming the production of fluorochemicals with its innovative technology that prioritizes safety, sustainability, and cost-effectiveness. The company has developed a patented process that eliminates the use of hazardous hydrofluoric acid, providing a cleaner alternative for industries such as agrochemicals, pharmaceuticals, and materials. By offering a safer means of accessing fluorochemicals, FluoRok aims to support a more sustainable future while enabling businesses to meet their production needs without compromising safety or environmental standards.

Iota Sciences

Venture Round in 2024
Iota Sciences Ltd. is a company based in Oxford, United Kingdom, founded in 2016. It specializes in developing and delivering innovative tools and technologies that utilize fluid shaping technologies to enhance drug discovery processes. The company focuses on creating fluidic mu-wells specifically designed for cell biology applications, aiming to advance research and discovery in this field. Through its unique capabilities, Iota Sciences seeks to facilitate significant advancements in the understanding and manipulation of cellular systems.

PQShield

Series B in 2024
PQShield Ltd specializes in post-quantum cryptographic solutions aimed at securing technology infrastructures against potential threats posed by quantum computing. Founded in 2018 and based in Oxford, United Kingdom, the company develops a range of products including PQSoC, a toolkit for post-quantum system on chip crypto co-processors, PQSDK, which integrates post-quantum primitives with the OpenSSL API, and PQE2E, a software development toolkit designed for secure data in transit messaging. PQShield's innovations help businesses transition from traditional cryptographic standards to quantum-secure alternatives, ensuring the protection of sensitive data and communications. The company is actively involved in standardization efforts globally, advancing cybersecurity practices in the face of evolving technological challenges.

Fractile

Pre Seed Round in 2024
Fractile is building chips to run large language models two orders of magnitude faster. Existing hardware is good for training LLMs, but very poorly suited to subsequent inference of the trained model, which is increasingly the dominant workload. A network’s weights need to be moved onto a chip once per word generated, and this movement takes a few hundred times longer than the subsequent computations themselves. Fractile’s revolutionary approach to fusing computation with memory eliminates this bottleneck, and can scale to allow running the world’s largest models at a global scale.

Amber Therapeutics

Series A in 2024
Amber Therapeutics develops the next-generation of bioelectrical therapies that can sense and adapt as well as stimulate, with the potential to radically improve clinical outcomes in patients with functional disorders of the peripheral nervous system.

Greywolf Therapeutics

Series B in 2024
Many cancers and other diseases are caused, or resist treatment, because T cells can't recognize or target cells correctly.​ We're progressing first-in-class antigen modulators through the clinic, developed to treat disease by controlling T cell activation. Our technology modulates antigen presentation, flicking a switch inside cells to alter their appearance to the immune system.​ This approach marks a fundamental shift in how we treat people living with autoimmune disorders, cancers and infectious diseases.

Oxford Endovascular

Series A in 2024
Oxford Endovascular is focused on developing an innovative medical device for the treatment of brain aneurysms. The company's technology employs a laser-cut metal alloy with shape-memory properties, which can be inserted into a patient's brain via a catheter. Once in place, the device expands into a tiny mesh tube, known as a flow diverter, that conforms to the natural shape of the blood vessel. This design effectively diverts blood flow away from the aneurysm, facilitating its healing and reducing the risk of rupture. By utilizing advanced origami engineering, Oxford Endovascular aims to enhance patient outcomes and improve survival rates for those affected by intracranial aneurysms.

Theolytics

Venture Round in 2024
Theolytics Limited is a clinical-stage biotechnology company founded in 2017 and based in Oxford, United Kingdom. The company specializes in developing oncolytic viral therapies to combat cancer, utilizing a phenotypic screening platform that facilitates the discovery and development of effective, targeted treatment candidates. These therapies are designed for intravenous delivery and tailored to specific patient populations, aiming to provide innovative care options. In addition to advancing its internal pipeline of programs that address both solid and liquid tumors, Theolytics is also focused on forming strategic partnerships to enhance and expedite its pipeline development.

Oxford Quantum Circuits

Series B in 2023
Oxford Quantum Circuits specializes in quantum computing technology that aims to address significant global challenges, such as climate change and drug discovery. The company has developed a fully functional quantum computer that integrates control systems, hardware, and software, enabling customers to streamline operations and explore innovative solutions. Their unique superconducting circuits are designed to maintain high qubit quality and control, which is essential for achieving commercially viable processing power. By leveraging this advanced technology, Oxford Quantum Circuits supports a range of applications, from pioneering new battery technologies to facilitating life-changing discoveries in medicine.

Sitryx Therapeutics

Series A in 2023
Sitryx Therapeutics is a biopharmaceutical company founded in 2018 and headquartered in Oxford, United Kingdom. The company focuses on developing innovative disease-modifying therapeutics in the fields of immuno-oncology and immuno-inflammation by regulating cell metabolism. Sitryx aims to enhance immune cell functions to inhibit tumor growth and improve immune responses. Co-founded by leading scientists from the United States and Europe, the company has attracted significant investment, including $30 million in Series A funding from a consortium of specialist investors. Sitryx has established a diverse pipeline of projects at various stages of drug discovery, positioning itself at the forefront of immunometabolism research.

Navenio

Series A in 2023
Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

Theolytics

Series A in 2023
Theolytics Limited is a clinical-stage biotechnology company founded in 2017 and based in Oxford, United Kingdom. The company specializes in developing oncolytic viral therapies to combat cancer, utilizing a phenotypic screening platform that facilitates the discovery and development of effective, targeted treatment candidates. These therapies are designed for intravenous delivery and tailored to specific patient populations, aiming to provide innovative care options. In addition to advancing its internal pipeline of programs that address both solid and liquid tumors, Theolytics is also focused on forming strategic partnerships to enhance and expedite its pipeline development.

Prolific

Series A in 2023
Prolific operates an online platform that facilitates the recruitment of survey participants, enabling researchers to gather high-quality psychological and behavioral data quickly and ethically. By connecting diverse individuals from around the globe, Prolific enhances the efficiency of data collection and ensures that users can find suitable participants for their studies on demand. The platform allows users to specify their target audience and rewards participants for their involvement, thereby promoting engagement and reliability in research efforts. Prolific's mission focuses on making trustworthy data more accessible, ultimately contributing to improved human knowledge and informed decision-making.

Beacon Therapeutics

Series A in 2023
Beacon Therapeutics is a clinical-stage biotechnology company that specializes in ophthalmic gene therapy aimed at restoring and improving vision for patients with rare retinal diseases that can lead to blindness. Utilizing a proprietary gene therapy platform, the company develops innovative genetic therapies tailored for individuals suffering from rare and debilitating conditions, particularly in the fields of ophthalmology and pulmonary medicine. Through its work, Beacon Therapeutics seeks to transform the lives of patients facing severe health challenges by offering potential breakthrough treatments.

Caristo Diagnostics

Series A in 2023
Caristo Diagnostics Limited, founded in 2018 as a spin-out from the University of Oxford, specializes in artificial intelligence-based software for diagnosing cardiovascular conditions. The company has developed the CaRi-Heart technology, an advanced imaging platform that enhances the prediction and diagnosis of coronary artery disease, heart attacks, strokes, and diabetes. Utilizing Cardiac Computed Tomography Angiography (CCTA), the platform measures the Fat Attenuation Index (FAI), a patented biomarker for coronary inflammation. The CaRi-Heart Report provides clinicians with critical insights, including patient-specific FAI, an assessment of the absolute 8-year risk of a fatal heart attack, and detailed characterization of coronary plaque. The technology is CE Mark certified and has received recognition in prestigious medical journals, showcasing its efficacy in predicting heart attacks. Caristo has secured over £23 million in venture capital and has been supported by various UK government grants for its innovative care pathways. With its unique combination of clinical insights and advanced technology, Caristo aims to transform cardiac care globally by improving risk prediction and prevention strategies.

Mixergy

Venture Round in 2023
Mixergy Ltd, founded in 2014 and based in Cassington, United Kingdom, specializes in the development of energy storage equipment, particularly hot water tanks. The company aims to provide cost-effective solutions that enhance energy efficiency and support the integration of renewable energy sources. By optimizing the use of solar photovoltaic systems and heat pumps, Mixergy tanks contribute to grid balancing, promoting greater utilization of renewable power generation.

Quantrol Ox

Seed Round in 2023
QuantrolOx is building automated machine learning-based control software for quantum technologies to tune, stabilize, and optimize qubits.

Mind Foundry

Series B in 2023
Mind Foundry Limited, headquartered in Oxford, United Kingdom, was founded in 2015 and specializes in developing software that helps organizations extract valuable insights from their data. As a spin-off from Oxford University, Mind Foundry combines innovation with usability through its Responsible AI platform, which addresses significant real-world challenges across various sectors, including insurance, infrastructure, and defense. The company’s technologies apply machine learning and advanced algorithmic modeling to enhance decision-making and problem-solving capabilities for clients. Founded by noted AI and machine learning experts, Mind Foundry aims to foster collaboration between humans and AI, promoting responsible and transparent AI usage while tackling pressing issues such as insurance fraud detection and complex signal processing.

Quantum Motion

Series B in 2023
Quantum Motion Technologies is focused on developing universal quantum computers utilizing silicon-based, CMOS-compatible processes. The company aims to address key challenges in quantum computing, such as fault tolerance and qubit redundancy, by creating scalable architectural technologies. By leveraging complementary metal-oxide semiconductor processing, Quantum Motion strives to achieve greater qubit density, enabling the construction of large-scale quantum systems. This approach not only enhances the performance of quantum computers but also assists clients in the quantum technology sector in overcoming significant errors and critical challenges in quantum information processing.

Archangel Lightworks

Seed Round in 2023
Archangel Lightworks is a company specializing in laser communications technology aimed at enhancing space-ground connectivity. By developing secure, wireless systems that utilize laser transmission, the company addresses the limitations of traditional radio communications, which are often bandwidth-constrained and lack security. Archangel Lightworks produces a range of products, including space terminals for satellites, air terminals for drones and manned aircraft, and ground communication terminals. These innovations provide the aerospace sector with resilient connectivity solutions, paving the way for the future of space-enabled networks.

Greywolf Therapeutics

Series B in 2023
Many cancers and other diseases are caused, or resist treatment, because T cells can't recognize or target cells correctly.​ We're progressing first-in-class antigen modulators through the clinic, developed to treat disease by controlling T cell activation. Our technology modulates antigen presentation, flicking a switch inside cells to alter their appearance to the immune system.​ This approach marks a fundamental shift in how we treat people living with autoimmune disorders, cancers and infectious diseases.

Amber Therapeutics

Seed Round in 2023
Amber Therapeutics develops the next-generation of bioelectrical therapies that can sense and adapt as well as stimulate, with the potential to radically improve clinical outcomes in patients with functional disorders of the peripheral nervous system.

Oxford Ionics

Series A in 2023
Oxford Ionics is a quantum computing startup focused on advancing the development of reliable quantum computers through its innovative use of trapped-ion technology. By combining high-performance qubits with noiseless electronic qubit control, the company offers solutions that allow for precise manipulation of qubits with minimal noise. This technology supports the creation of scalable quantum chips using standard semiconductor fabrication methods, which enhances efficiency and facilitates significant progress in the quantum computing market. Clients benefit from improved computational capabilities, enabling them to tackle complex problem-solving tasks more effectively.

BehaVR

Series B in 2022
BehaVR, LLC, established in 2016 and headquartered in Elizabethtown, Kentucky, operates a virtual reality platform designed to enhance practices and treatments within the healthcare sector. The company specializes in developing digital therapeutics for behavioral health, particularly at the intersection of behavioral health and chronic disease management. BehaVR's focus is on fostering skills such as stress resilience, emotional regulation, and self-efficacy, which aid individuals in coping with their conditions, adhering to care plans, and ultimately improving their overall health outcomes.

Osler Diagnostics

Series C in 2022
Osler Diagnostics is a UK-based company focused on providing accessible health diagnostics. Established in 2017 from research at the University of Oxford, Osler has developed the Osler Origin, a portable laboratory capable of delivering lab-quality diagnostics anywhere, anytime. This innovative device requires only a drop of blood to test for a wide range of biomarkers, allowing users to monitor various health markers conveniently. Osler aims to serve diverse healthcare settings globally, empowering individuals to understand and manage their health more effectively. The company is headquartered in Oxford, UK.

Util

Seed Round in 2022
Util is a developer of sustainability intelligence technology that provides investors with an objective, evidence-based assessment of a company's impact. By leveraging big data and machine learning, Util aggregates and analyzes comprehensive company data related to various stakeholders, including employees, customers, and the environment. This information is transformed into a dollar-based annual value generated metric, enabling responsible investors to evaluate both financial and non-financial returns. The company's innovative methodology goes beyond traditional ESG metrics, portraying companies as complex value generators. Util's product encompasses all listed securities and is specifically designed for investment managers seeking advanced analysis that aligns with the efficiencies of financial reporting. Currently, Util collaborates with two investment manager partners who collectively manage $130 billion in assets to refine its methodology and product offerings.

Nucleome Therapeutics

Series A in 2022
Nucleome Therapeutics is a biotechnology company based in Oxford, United Kingdom, focused on transforming drug discovery by decoding the complexities of the human genome. Founded in 2019, the company utilizes a unique genomics platform that leverages the three-dimensional structure of the genome and machine learning to explore the vast, largely uncharted regions of the genome, often referred to as the dark matter. This area contains over 95% of disease-linked genetic variants, providing significant opportunities for identifying new therapeutic targets. Nucleome Therapeutics specializes in creating high-resolution genome structure maps and validating genetic variants in primary cell types, facilitating the discovery and development of novel precision medicines. The company's initial emphasis is on lymphocytes and autoimmune diseases, with the goal of establishing a robust pipeline of drug candidates and corresponding biomarkers. Founded by experts in gene regulation from the University of Oxford, Nucleome is backed by investments from Oxford Sciences Innovation.

Opsydia

Venture Round in 2022
Opsydia is set to disrupt a number of industries by its ability to create practically invisible structures inside transparent materials. Permanent and inimitable serial numbers, images or cryptographic data can be laser-written without compromising the integrity of the material or modifying its surface. Material applications include diamond, glass and polymers

Oxford Quantum Circuits

Series A in 2022
Oxford Quantum Circuits specializes in quantum computing technology that aims to address significant global challenges, such as climate change and drug discovery. The company has developed a fully functional quantum computer that integrates control systems, hardware, and software, enabling customers to streamline operations and explore innovative solutions. Their unique superconducting circuits are designed to maintain high qubit quality and control, which is essential for achieving commercially viable processing power. By leveraging this advanced technology, Oxford Quantum Circuits supports a range of applications, from pioneering new battery technologies to facilitating life-changing discoveries in medicine.

MiroBio

Series B in 2022
MiroBio's platform is based on ground-breaking research by their scientific founders at the University of Oxford delineating how immune cells communicate and how they are activated. These insights have enabled MiroBio to create antibodies that can leverage natural signalling mechanisms to restore immune system balance and control.

BibliU

Series B in 2022
BibliU Ltd is a software company headquartered in London, UK, with an additional office in New York, that specializes in providing a digital platform for accessing textbooks and educational resources. Founded in 2014, BibliU enables students to access textbooks and other course materials online through various devices, allowing for flexible study options. The company's platform offers features such as offline support, a discovery search tool, and tools for synchronized highlights and comments, enhancing the learning experience and productivity. BibliU collaborates with numerous publishers and open educational resource providers to offer a vast array of digital content, making academic materials more accessible and affordable for colleges and universities.

ORCA Computing

Series A in 2022
ORCA Computing is building the first scalable and flexible quantum computer powered by photonics. They build a photonic Quantum computer, based on quantum memories. ORCA'a technology allows storage and synchronization of quantum operations, leading to improved performances.

MoA Technology

Series B in 2022
MoA Technology Ltd. is a plant genetics company based in Leeds, United Kingdom, that was incorporated in 2017. It was spun out from the University of Oxford and focuses on developing innovative agricultural technologies aimed at enabling farmers to produce healthy food through sustainable crop systems. The company leverages research led by Professor Liam Dolan to discover new methods that enhance agricultural productivity while promoting sustainability.

Salience Labs

Seed Round in 2022
Salience Labs specializes in developing hybrid photonic-electronic chips tailored for artificial intelligence applications. Originating from extensive research at the University of Oxford and the University of Münster, the company focuses on silicon photonics to meet the increasing demands of AI workloads in data center infrastructure. Its flagship product, an optical switch, enables all-optical networking between computing nodes, effectively addressing data movement bottlenecks. By utilizing photons instead of electrons for data processing, Salience Labs' technology significantly reduces power consumption while enhancing processing speeds. This innovative approach aims to transform the hardware landscape necessary for maximizing AI capabilities, providing low-latency, high-bandwidth networking that accelerates job completion and lowers operational costs.

OMass Therapeutics

Series B in 2022
OMass Therapeutics Limited is a biotechnology company based in Oxford, United Kingdom, that specializes in drug discovery through structural mass spectrometry. Founded in 2016, the company employs innovative mass spectrometry platforms to develop therapeutics aimed at difficult disease targets. By providing access to native mass spectrometry, OMass Therapeutics enables clients in the biotechnology and pharmaceutical sectors to study complex protein assemblies and their interactions with other biological molecules. This approach allows clients to address challenging drug targets and biotherapeutics more effectively, fostering a collaborative environment for advancing novel medicines.

Scenic Biotech

Series A in 2022
Scenic Biotech is a biotechnology company focused on developing innovative genomics and immunotherapy technologies aimed at addressing severe diseases, including cancer and rare genetic disorders. The company's approach involves identifying genetic suppressors, which are genes that can counteract the effects of disease-causing mutations, thus serving as new drug targets. By leveraging its advanced technology, Scenic Biotech enables scientists to rapidly identify and validate these novel drug targets, facilitating the development of disease-modifying therapeutics. This targeted strategy not only enhances the understanding of genetic influences on diseases but also aims to improve treatment outcomes for affected patients.

First Light Fusion

Series C in 2022
First Light Fusion Limited, founded in 2011 and based in Begbroke, United Kingdom, specializes in advanced implosion processes for electricity generation through inertial confinement fusion. The company originated as a spin-out from the University of Oxford and actively engages in researching and developing sustainable renewable energy solutions. It employs a team of engineers and physicists and collaborates with several academic institutions, including the University of Oxford, Warwick University, UCL, and Imperial College London. First Light Fusion focuses on harnessing fundamental physics to discover new energy sources, utilizing detailed numerical simulations and experimental validation in its research efforts.

PQShield

Series A in 2022
PQShield Ltd specializes in post-quantum cryptographic solutions aimed at securing technology infrastructures against potential threats posed by quantum computing. Founded in 2018 and based in Oxford, United Kingdom, the company develops a range of products including PQSoC, a toolkit for post-quantum system on chip crypto co-processors, PQSDK, which integrates post-quantum primitives with the OpenSSL API, and PQE2E, a software development toolkit designed for secure data in transit messaging. PQShield's innovations help businesses transition from traditional cryptographic standards to quantum-secure alternatives, ensuring the protection of sensitive data and communications. The company is actively involved in standardization efforts globally, advancing cybersecurity practices in the face of evolving technological challenges.

Animal Dynamics

Series A in 2022
Animal Dynamics specializes in developing advanced robotics and systems inspired by the principles of evolutionary biomechanics. The company leverages recent advancements in analytical technology to conduct in-depth studies of high-performance animals, allowing for a nuanced understanding of their efficient and powerful designs. By integrating fine engineering with insights from nature, Animal Dynamics creates innovative robotic vehicles capable of superior performance across various applications, including crop spraying, surveying, fire suppression, and humanitarian aid. This approach not only aims to replicate nature's designs but also to enhance them through the use of cutting-edge materials science, microelectronics, and software engineering, ultimately striving to deliver solutions that are both effective and environmentally conscious.

natcap

Seed Round in 2021
natcap is a nature intelligence company that provides report and act on impacts and dependencies on nature.

ONI

Series B in 2021
ONI is a leader in super-resolution microscopy, offering innovative tools that enhance biological research. The company has developed the Nanoimager, the first benchtop super-resolution microscope, which provides unprecedented usability and precision for researchers. This device enables access to various super-resolution techniques, including dSTORM, PALM, smFRET, and single-particle tracking, facilitating a deeper understanding of cellular structures and functions. ONI's products are increasingly adopted by academic researchers and pharmaceutical companies, with installations in prominent laboratories such as those at the Universities of Oxford, Cambridge, and Harvard. The company's mission is to democratize scientific discovery by making advanced imaging technology more accessible and affordable, thereby empowering researchers to visualize and share the intricate details of life. Recognized for its innovative contributions, ONI has received accolades such as being named a Disruptor to Watch and winning Best Business Start-up at the IOP Awards. Through its commitment to advancing scientific research, ONI aims to accelerate discoveries that can lead to improved health outcomes.

Alethiomics

Seed Round in 2021
Alethiomics is a pre-clinical biotech company harnessing the power of single-cell multi-omic technology to discover and develop life-changing treatments for patients with blood cancer.

Navenio

Venture Round in 2021
Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

Ultromics

Series B in 2021
They are building world-class diagnostic aids to help cardiologists — powered by artificial intelligence. To date, they have developed the world’s most accurate echocardiography software to improve the diagnosis of coronary heart disease by more than 90%.

Pepgen

Venture Round in 2021
PepGen is a clinical-stage biotechnology company based in Oxford, United Kingdom, focused on advancing nucleic acid therapeutics, particularly antisense oligonucleotides. Founded in 2018, the company aims to enhance the delivery and efficacy of these therapies through its proprietary Enhanced Delivery Oligonucleotide (EDO) platform. This innovative platform utilizes engineered peptides designed to improve tissue penetration, cellular uptake, and nuclear delivery of oligonucleotides. PepGen's technology has shown promise in preclinical studies, demonstrating the ability to transport therapeutics effectively into various target tissues, including smooth, skeletal, and cardiac muscle, as well as the central nervous system. The company's mission is to unlock the full potential of nucleic acid therapeutics to transform the treatment landscape for severe neuromuscular and neurological diseases.

Rey

Series A in 2021
Rey is a membership-based, on-demand mental health company on a mission to revolutionize mental health and wellness by improving access to personalized services through technology.

Orbit Discovery

Venture Round in 2021
Orbit Discovery Ltd. is a biotechnology company specializing in peptide display technology to discover peptide drugs for chronic diseases. Established in 2015 and based in Oxford, United Kingdom, the company utilizes an innovative in vitro bead display platform that links randomized peptide sequences to their encoding DNA. This technology enables high-throughput screening of peptides, facilitating the identification and optimization of potential drug candidates. By combining the specificity and efficacy of large biologic molecules with the advantages of small molecules, such as lower manufacturing costs and simpler delivery methods, Orbit Discovery aims to address a wide range of chronic diseases affecting large patient populations. The company's focus is on both internal drug discovery programs and collaborative research efforts, streamlining the discovery process and accelerating the development of new peptide therapeutics.

Omega Crop

Seed Round in 2021
Omega Crop specializes in advanced crop modeling and remote-sensing technology to enhance agricultural performance. By integrating geostatistics with a comprehensive data ecosystem, Omega Crop forecasts crop performance risks and assists farmers in making informed decisions. Their innovative approach combines various data sources, including satellites, drones, mobile devices, and localized weather information, to deliver detailed assessments of farming operations. This allows growers to accurately predict yields, thereby optimizing productivity and increasing revenue. Through these technologies, Omega Crop aims to support farmers in their efforts to sustainably feed the growing global population.

Oxford Endovascular

Series A in 2021
Oxford Endovascular is focused on developing an innovative medical device for the treatment of brain aneurysms. The company's technology employs a laser-cut metal alloy with shape-memory properties, which can be inserted into a patient's brain via a catheter. Once in place, the device expands into a tiny mesh tube, known as a flow diverter, that conforms to the natural shape of the blood vessel. This design effectively diverts blood flow away from the aneurysm, facilitating its healing and reducing the risk of rupture. By utilizing advanced origami engineering, Oxford Endovascular aims to enhance patient outcomes and improve survival rates for those affected by intracranial aneurysms.

Caristo Diagnostics

Venture Round in 2021
Caristo Diagnostics Limited, founded in 2018 as a spin-out from the University of Oxford, specializes in artificial intelligence-based software for diagnosing cardiovascular conditions. The company has developed the CaRi-Heart technology, an advanced imaging platform that enhances the prediction and diagnosis of coronary artery disease, heart attacks, strokes, and diabetes. Utilizing Cardiac Computed Tomography Angiography (CCTA), the platform measures the Fat Attenuation Index (FAI), a patented biomarker for coronary inflammation. The CaRi-Heart Report provides clinicians with critical insights, including patient-specific FAI, an assessment of the absolute 8-year risk of a fatal heart attack, and detailed characterization of coronary plaque. The technology is CE Mark certified and has received recognition in prestigious medical journals, showcasing its efficacy in predicting heart attacks. Caristo has secured over £23 million in venture capital and has been supported by various UK government grants for its innovative care pathways. With its unique combination of clinical insights and advanced technology, Caristo aims to transform cardiac care globally by improving risk prediction and prevention strategies.

Barinthus Biotherapeutics

Series B in 2021
Barinthus Biotherapeutics is a clinical-stage biopharmaceutical company focused on the discovery and development of innovative immunotherapeutics and vaccines aimed at treating and preventing infectious diseases and cancer. The company's proprietary platform includes modified simian adenoviral vectors known as ChAdOx1 and ChAdOx2, as well as a Modified Vaccinia Ankara (MVA) boost vector, both of which have established safety profiles and do not replicate in humans. This platform has shown to elicit significantly higher levels of CD8+ T cells compared to other technologies. Barinthus Biotherapeutics maintains a diverse pipeline that includes both clinical and preclinical therapeutic programs addressing solid tumors and viral infections, alongside prophylactic vaccine candidates. The company has also collaborated on the development of a COVID-19 vaccine in partnership with the University of Oxford, which has been licensed for global use.

Genomics

Venture Round in 2021
Genomics plc is focused on transforming healthcare through advanced genomic analysis. The company employs sophisticated methodologies to analyze large integrated datasets of genomic and phenotypic information, aiming to enhance understanding of human biology. By leveraging genetic inference technology, Genomics plc seeks to identify new drug targets for serious diseases and assess individual disease risk. Their analytical platform enables the exploration of genomic sequence data, providing valuable insights that support pharmaceutical companies in reducing risks associated with drug development. This approach not only aims to improve healthcare outcomes but also sets a standard for how organizations and patients can benefit from genomic data.

Evox Therapeutics

Series C in 2021
Evox Therapeutics is a biotechnology company based in Oxford, United Kingdom, founded in 2016. The company specializes in developing exosome-based therapeutics aimed at treating rare and severe diseases. By harnessing and engineering the natural delivery capabilities of extracellular vesicles, known as exosomes, Evox focuses on creating innovative drug delivery systems that utilize nucleic acids and proteins. This technology allows for targeted delivery to specific organs, including the brain and central nervous system, addressing limitations often encountered with traditional therapies. Evox's proprietary methods for modifying exosomes enhance their ability to transport therapeutic agents effectively, thereby improving treatment options for patients with limited alternatives. The company is supported by a strong intellectual property portfolio and investments from leading life sciences venture capital groups, positioning it as a leader in the emerging field of exosome-based therapeutics.

SpyBiotech

Series A in 2021
SpyBiotech Limited, founded in 2017 and based in Oxford, United Kingdom, specializes in the development of innovative vaccines using a proprietary technology known as molecular superglue. This platform allows for the rapid creation of bonding vaccines by attaching antigens to viruses and other particles, enhancing the vaccine development process. By leveraging this unique approach, SpyBiotech aims to provide medical institutions and research centers with more effective vaccines that can be developed in a shorter timeframe, ultimately improving immunity against various diseases, including bacterial infections.

Theolytics

Series A in 2021
Theolytics Limited is a clinical-stage biotechnology company founded in 2017 and based in Oxford, United Kingdom. The company specializes in developing oncolytic viral therapies to combat cancer, utilizing a phenotypic screening platform that facilitates the discovery and development of effective, targeted treatment candidates. These therapies are designed for intravenous delivery and tailored to specific patient populations, aiming to provide innovative care options. In addition to advancing its internal pipeline of programs that address both solid and liquid tumors, Theolytics is also focused on forming strategic partnerships to enhance and expedite its pipeline development.

Living Optics

Seed Round in 2021
Living Optics Limited, founded in 2019 and based in Oxford, United Kingdom, specializes in the design and development of compact hyperspectral imaging cameras and related software. The company's innovative technology captures data that is not visible to the human eye or traditional cameras, making hyperspectral imaging more accessible and affordable for a variety of applications in consumer products, medical devices, and the manufacturing industry. Living Optics aims to empower computer vision developers and scientists by providing portable solutions that enable the integration of spectral imaging data into new research and applications. In September 2022, the company secured $25 million in Series A funding to further its mission of revolutionizing the imaging market.

DJS Antibodies

Venture Round in 2020
DJS Antibodies Ltd, founded in 2014 and based in Bicester, United Kingdom, focuses on the design and discovery of novel therapeutic monoclonal antibodies targeting G-protein-coupled receptors (GPCRs). The company specializes in developing innovative therapeutics aimed at treating chronic inflammatory diseases, utilizing breakthrough technology to create first-in-class antibodies against challenging disease targets. By isolating high-quality antibodies against complex protein targets that have previously proven difficult for drug discovery, DJS Antibodies aims to provide effective treatments for conditions that are currently undruggable and untreatable.

T-Cypher Bio

Seed Round in 2020
T-Cypher Bio is an early-stage biotechnology company. T-Cypher Bio we believe that TCR-based therapeutics have the potential to transform the treatment of solid tumors, as well as autoimmune, inflammatory, and infectious diseases. Yet challenges in the identification of therapeutically relevant targets and TCRs have limited the application of such therapies. T-Cypher’s integrated platform, D-Cypher, overcomes these challenges.

Pepgen

Series A in 2020
PepGen is a clinical-stage biotechnology company based in Oxford, United Kingdom, focused on advancing nucleic acid therapeutics, particularly antisense oligonucleotides. Founded in 2018, the company aims to enhance the delivery and efficacy of these therapies through its proprietary Enhanced Delivery Oligonucleotide (EDO) platform. This innovative platform utilizes engineered peptides designed to improve tissue penetration, cellular uptake, and nuclear delivery of oligonucleotides. PepGen's technology has shown promise in preclinical studies, demonstrating the ability to transport therapeutics effectively into various target tissues, including smooth, skeletal, and cardiac muscle, as well as the central nervous system. The company's mission is to unlock the full potential of nucleic acid therapeutics to transform the treatment landscape for severe neuromuscular and neurological diseases.

Refeyn

Series A in 2020
Refeyn Ltd, founded in 2018 and based in Oxford, United Kingdom, specializes in mass photometry technology for the analysis of biomolecules. The company's flagship product, Refeyn One, employs single molecule light scattering to detect, image, and accurately determine the mass of biomolecules in solution. This innovative optical technology allows researchers to measure the mass of individual molecules in their native state without the necessity for labels, providing both quality-control instruments and advanced research tools. Refeyn's offerings enable scientists to conduct mass measurements across a range of biologically relevant concentrations, enhancing the capabilities of biomolecular analysis.

ORCA Computing

Pre Seed Round in 2020
ORCA Computing is building the first scalable and flexible quantum computer powered by photonics. They build a photonic Quantum computer, based on quantum memories. ORCA'a technology allows storage and synchronization of quantum operations, leading to improved performances.

PQShield

Seed Round in 2020
PQShield Ltd specializes in post-quantum cryptographic solutions aimed at securing technology infrastructures against potential threats posed by quantum computing. Founded in 2018 and based in Oxford, United Kingdom, the company develops a range of products including PQSoC, a toolkit for post-quantum system on chip crypto co-processors, PQSDK, which integrates post-quantum primitives with the OpenSSL API, and PQE2E, a software development toolkit designed for secure data in transit messaging. PQShield's innovations help businesses transition from traditional cryptographic standards to quantum-secure alternatives, ensuring the protection of sensitive data and communications. The company is actively involved in standardization efforts globally, advancing cybersecurity practices in the face of evolving technological challenges.

Oxford Ionics

Seed Round in 2020
Oxford Ionics is a quantum computing startup focused on advancing the development of reliable quantum computers through its innovative use of trapped-ion technology. By combining high-performance qubits with noiseless electronic qubit control, the company offers solutions that allow for precise manipulation of qubits with minimal noise. This technology supports the creation of scalable quantum chips using standard semiconductor fabrication methods, which enhances efficiency and facilitates significant progress in the quantum computing market. Clients benefit from improved computational capabilities, enabling them to tackle complex problem-solving tasks more effectively.

Oxford Flow

Venture Round in 2020
Oxford Flow Ltd. is a company that designs, manufactures, and supplies pressure control equipment, including gas regulators, water pressure reducing valves (PRVs), silencers, and pilots. Established in 2015 and based in Oxford, United Kingdom, the company serves a variety of industries such as water, gas, marine, oil and gas, process, power, and building services. Oxford Flow's products are engineered to simplify systems and enhance reliability while meeting rigorous standards for water quality and leakage control. The company focuses on delivering practical solutions that improve operational efficiency and reduce environmental impact, backed by extensive testing and customer feedback. By combining academic expertise with industry knowledge, Oxford Flow aims to provide innovative and efficient pressure control solutions that help customers save costs without compromising performance.

Base Genomics

Seed Round in 2020
Base Genomics is an epigenetics company based on TAPS (TET-assisted pyridine borane sequencing), a new invention to sequence DNA methylation developed at the Ludwig Institute for Cancer Research Branch at the University of Oxford. TAPS is a novel chemical reaction that converts methylated cytosine to thymine under mild conditions. Unlike bisulfite sequencing, TAPS does not degrade DNA, meaning that more DNA is available for sequencing. It also retains sequence complexity, cutting sequencing costs and enabling simultaneous epigenetic and genetic analysis.

Navenio

Series A in 2020
Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

Quantum Motion

Series A in 2020
Quantum Motion Technologies is focused on developing universal quantum computers utilizing silicon-based, CMOS-compatible processes. The company aims to address key challenges in quantum computing, such as fault tolerance and qubit redundancy, by creating scalable architectural technologies. By leveraging complementary metal-oxide semiconductor processing, Quantum Motion strives to achieve greater qubit density, enabling the construction of large-scale quantum systems. This approach not only enhances the performance of quantum computers but also assists clients in the quantum technology sector in overcoming significant errors and critical challenges in quantum information processing.

BibliU

Series A in 2020
BibliU Ltd is a software company headquartered in London, UK, with an additional office in New York, that specializes in providing a digital platform for accessing textbooks and educational resources. Founded in 2014, BibliU enables students to access textbooks and other course materials online through various devices, allowing for flexible study options. The company's platform offers features such as offline support, a discovery search tool, and tools for synchronized highlights and comments, enhancing the learning experience and productivity. BibliU collaborates with numerous publishers and open educational resource providers to offer a vast array of digital content, making academic materials more accessible and affordable for colleges and universities.

Living Optics

Seed Round in 2020
Living Optics Limited, founded in 2019 and based in Oxford, United Kingdom, specializes in the design and development of compact hyperspectral imaging cameras and related software. The company's innovative technology captures data that is not visible to the human eye or traditional cameras, making hyperspectral imaging more accessible and affordable for a variety of applications in consumer products, medical devices, and the manufacturing industry. Living Optics aims to empower computer vision developers and scientists by providing portable solutions that enable the integration of spectral imaging data into new research and applications. In September 2022, the company secured $25 million in Series A funding to further its mission of revolutionizing the imaging market.

Perspectum

Venture Round in 2020
Perspectum is a global medical technology company that focuses on improving care for patients with liver disease, diabetes, and cancer. By utilizing advanced imaging and genetics, the company emphasizes precision medicine to enhance early detection, diagnosis, and targeted treatment of complex health issues. Perspectum's diverse team, which includes physicians, biomedical scientists, engineers, and technologists, works collaboratively to develop innovative digital technologies. Their aim is to empower both patients and clinicians by providing quantitative health assessments, enabling more effective management of metabolic diseases and multi-organ pathology.

Animal Dynamics

Series A in 2020
Animal Dynamics specializes in developing advanced robotics and systems inspired by the principles of evolutionary biomechanics. The company leverages recent advancements in analytical technology to conduct in-depth studies of high-performance animals, allowing for a nuanced understanding of their efficient and powerful designs. By integrating fine engineering with insights from nature, Animal Dynamics creates innovative robotic vehicles capable of superior performance across various applications, including crop spraying, surveying, fire suppression, and humanitarian aid. This approach not only aims to replicate nature's designs but also to enhance them through the use of cutting-edge materials science, microelectronics, and software engineering, ultimately striving to deliver solutions that are both effective and environmentally conscious.

OMass Therapeutics

Series A in 2020
OMass Therapeutics Limited is a biotechnology company based in Oxford, United Kingdom, that specializes in drug discovery through structural mass spectrometry. Founded in 2016, the company employs innovative mass spectrometry platforms to develop therapeutics aimed at difficult disease targets. By providing access to native mass spectrometry, OMass Therapeutics enables clients in the biotechnology and pharmaceutical sectors to study complex protein assemblies and their interactions with other biological molecules. This approach allows clients to address challenging drug targets and biotherapeutics more effectively, fostering a collaborative environment for advancing novel medicines.

Oxford VR

Series A in 2020
Oxford VR Limited specializes in developing cognitive treatments for various clinical conditions using virtual reality technology. Founded in 2016 and based in Oxford, United Kingdom, the company leverages extensive research from Professor Daniel Freeman to create automated therapies delivered by a virtual coach. These innovative treatments address issues such as fear of heights, psychosis, and social anxiety. By utilizing immersive VR experiences, Oxford VR aims to provide faster, more effective, and cost-efficient psychological interventions compared to traditional methods. The company's focus is on delivering clinically validated and user-centered solutions that enhance access to mental health care, benefiting patients, healthcare professionals, and the broader health system.

Alloyed

Series B in 2020
Alloyed, established in 2017 and based in Begbroke, United Kingdom, specializes in alloy design and optimization through its proprietary software, Alloys-by-Design. The company focuses on researching and developing advanced alloy methods, along with the manufacture and licensing of proprietary alloys, alloy powders, and components. Alloyed serves a diverse array of sectors, including aerospace, automotive, defense, medical devices, energy, and consumer goods. By leveraging data and advanced physical models, Alloyed's platform simulates the performance of millions of potential alloys simultaneously, facilitating optimization across various performance, manufacturing, and economic parameters. This approach enables clients to enhance their applications in critical industries.

Mixergy

Series A in 2019
Mixergy Ltd, founded in 2014 and based in Cassington, United Kingdom, specializes in the development of energy storage equipment, particularly hot water tanks. The company aims to provide cost-effective solutions that enhance energy efficiency and support the integration of renewable energy sources. By optimizing the use of solar photovoltaic systems and heat pumps, Mixergy tanks contribute to grid balancing, promoting greater utilization of renewable power generation.

MiroBio

Series A in 2019
MiroBio's platform is based on ground-breaking research by their scientific founders at the University of Oxford delineating how immune cells communicate and how they are activated. These insights have enabled MiroBio to create antibodies that can leverage natural signalling mechanisms to restore immune system balance and control.

YASA

Series C in 2019
YASA was founded on the principle that small, light electric motors would play a growing role in meeting both the strict emissions targets being set globally in a wide range of industries and the requirement for greater efficiency through electrification. The Company was incorporated in 2009 based on a unique patented motor technology invented by the Company’s founder and CTO Dr Tim Woolmer whilst studying for his DPhil at Oxford University. The unique YASA motor technology is ideal for a range of mobile applications such as hydraulics replacement, power generation, traction and propulsion and hybridisation. YASA Motors manufactures a range of standard electric motors and generators based on our unique motor topology at our factory and Company Headquarters in Abingdon, Oxfordshire. The YASA-750, YASA-250 and YASA-400 products have been designed to be integrated into customers’ products in a range of markets and industries with minimal application engineering. In addition to our standard products, YASA has a design and development team dedicated to making bespoke motors for customers for medium-high volume applications.

MoA Technology

Series A in 2019
MoA Technology Ltd. is a plant genetics company based in Leeds, United Kingdom, that was incorporated in 2017. It was spun out from the University of Oxford and focuses on developing innovative agricultural technologies aimed at enabling farmers to produce healthy food through sustainable crop systems. The company leverages research led by Professor Liam Dolan to discover new methods that enhance agricultural productivity while promoting sustainability.

Zegami

Series B in 2019
Zegami Limited is a company that specializes in visual data exploration tools designed for the analysis of large collections of images, particularly in scientific and medical contexts. Founded in 2015 and headquartered in Oxford, United Kingdom, Zegami transforms visual data into actionable information by integrating media, data, and artificial intelligence. Its platform supports users in searching, sorting, filtering, and grouping data, which facilitates the identification of patterns, correlations, and anomalies. The solution caters to a variety of sectors, including heating, ventilation, and air conditioning (HVAC) management, microscopy, genomics, and cultural heritage organizations such as galleries and museums. Additionally, Zegami offers a plugin API that enables developers to create custom visualizations, enhancing the platform's versatility and applicability across different fields.

Zegami

Series B in 2019
Zegami Limited is a company that specializes in visual data exploration tools designed for the analysis of large collections of images, particularly in scientific and medical contexts. Founded in 2015 and headquartered in Oxford, United Kingdom, Zegami transforms visual data into actionable information by integrating media, data, and artificial intelligence. Its platform supports users in searching, sorting, filtering, and grouping data, which facilitates the identification of patterns, correlations, and anomalies. The solution caters to a variety of sectors, including heating, ventilation, and air conditioning (HVAC) management, microscopy, genomics, and cultural heritage organizations such as galleries and museums. Additionally, Zegami offers a plugin API that enables developers to create custom visualizations, enhancing the platform's versatility and applicability across different fields.
Oxford Semantic Technologies is a company focused on developing RDFox, a high-performance knowledge graph and semantic reasoning engine designed to leverage modern multi-core architecture. Founded in 2017 as a spin-out from the University of Oxford, the company aims to translate advanced research in semantic web technologies into practical industrial applications. The RDFox engine, which started development in 2011, employs patented computing techniques that allow for the rapid processing of complex queries, significantly reducing the need for IT expertise. This capability enables domain experts to formulate their own queries, streamline development cycles for data analysis, and validate results through detailed explanations of how answers are derived from the underlying data. Oxford Semantic Technologies has positioned itself as a key player in unlocking innovative enterprise applications for its clients.

Albus Health

Convertible Note in 2019
Albus Health, a startup emerging from the University of Oxford, has created an intelligent nocturnal monitoring platform designed for personalized home use. This system facilitates passive, contactless, and objective monitoring of various symptoms and environmental metrics, making it particularly useful for assessing nocturnal conditions. The platform has been successfully commercialized and is currently employed by leading pharmaceutical companies to monitor nocturnal symptoms during clinical trials. Additionally, it has the capability to predict respiratory emergencies, thus enhancing patient safety and outcomes.

Genomics

Series B in 2018
Genomics plc is focused on transforming healthcare through advanced genomic analysis. The company employs sophisticated methodologies to analyze large integrated datasets of genomic and phenotypic information, aiming to enhance understanding of human biology. By leveraging genetic inference technology, Genomics plc seeks to identify new drug targets for serious diseases and assess individual disease risk. Their analytical platform enables the exploration of genomic sequence data, providing valuable insights that support pharmaceutical companies in reducing risks associated with drug development. This approach not only aims to improve healthcare outcomes but also sets a standard for how organizations and patients can benefit from genomic data.

OMass Therapeutics

Series A in 2018
OMass Therapeutics Limited is a biotechnology company based in Oxford, United Kingdom, that specializes in drug discovery through structural mass spectrometry. Founded in 2016, the company employs innovative mass spectrometry platforms to develop therapeutics aimed at difficult disease targets. By providing access to native mass spectrometry, OMass Therapeutics enables clients in the biotechnology and pharmaceutical sectors to study complex protein assemblies and their interactions with other biological molecules. This approach allows clients to address challenging drug targets and biotherapeutics more effectively, fostering a collaborative environment for advancing novel medicines.

Alloyed

Series A in 2018
Alloyed, established in 2017 and based in Begbroke, United Kingdom, specializes in alloy design and optimization through its proprietary software, Alloys-by-Design. The company focuses on researching and developing advanced alloy methods, along with the manufacture and licensing of proprietary alloys, alloy powders, and components. Alloyed serves a diverse array of sectors, including aerospace, automotive, defense, medical devices, energy, and consumer goods. By leveraging data and advanced physical models, Alloyed's platform simulates the performance of millions of potential alloys simultaneously, facilitating optimization across various performance, manufacturing, and economic parameters. This approach enables clients to enhance their applications in critical industries.

Covatic

Funding Round in 2018
Covatic Ltd, established in 2016 and headquartered in Birmingham, United Kingdom, specializes in broadcast personalization software. The company's innovative platform employs mobile-based algorithms to enhance user experience by delivering personalized content without compromising personal data. By identifying optimal engagement moments and methods for individuals, Covatic enables clients to effectively connect with their target audiences. This approach allows for the collection and personalization of insights, ultimately improving the way applications serve their users. With an emphasis on problem-solving, Covatic continues to develop solutions that enhance app functionality and user interaction.

Animal Dynamics

Series A in 2018
Animal Dynamics specializes in developing advanced robotics and systems inspired by the principles of evolutionary biomechanics. The company leverages recent advancements in analytical technology to conduct in-depth studies of high-performance animals, allowing for a nuanced understanding of their efficient and powerful designs. By integrating fine engineering with insights from nature, Animal Dynamics creates innovative robotic vehicles capable of superior performance across various applications, including crop spraying, surveying, fire suppression, and humanitarian aid. This approach not only aims to replicate nature's designs but also to enhance them through the use of cutting-edge materials science, microelectronics, and software engineering, ultimately striving to deliver solutions that are both effective and environmentally conscious.

Caristo Diagnostics

Seed Round in 2018
Caristo Diagnostics Limited, founded in 2018 as a spin-out from the University of Oxford, specializes in artificial intelligence-based software for diagnosing cardiovascular conditions. The company has developed the CaRi-Heart technology, an advanced imaging platform that enhances the prediction and diagnosis of coronary artery disease, heart attacks, strokes, and diabetes. Utilizing Cardiac Computed Tomography Angiography (CCTA), the platform measures the Fat Attenuation Index (FAI), a patented biomarker for coronary inflammation. The CaRi-Heart Report provides clinicians with critical insights, including patient-specific FAI, an assessment of the absolute 8-year risk of a fatal heart attack, and detailed characterization of coronary plaque. The technology is CE Mark certified and has received recognition in prestigious medical journals, showcasing its efficacy in predicting heart attacks. Caristo has secured over £23 million in venture capital and has been supported by various UK government grants for its innovative care pathways. With its unique combination of clinical insights and advanced technology, Caristo aims to transform cardiac care globally by improving risk prediction and prevention strategies.

Oxford VR

Venture Round in 2018
Oxford VR Limited specializes in developing cognitive treatments for various clinical conditions using virtual reality technology. Founded in 2016 and based in Oxford, United Kingdom, the company leverages extensive research from Professor Daniel Freeman to create automated therapies delivered by a virtual coach. These innovative treatments address issues such as fear of heights, psychosis, and social anxiety. By utilizing immersive VR experiences, Oxford VR aims to provide faster, more effective, and cost-efficient psychological interventions compared to traditional methods. The company's focus is on delivering clinically validated and user-centered solutions that enhance access to mental health care, benefiting patients, healthcare professionals, and the broader health system.

Evox Therapeutics

Series B in 2018
Evox Therapeutics is a biotechnology company based in Oxford, United Kingdom, founded in 2016. The company specializes in developing exosome-based therapeutics aimed at treating rare and severe diseases. By harnessing and engineering the natural delivery capabilities of extracellular vesicles, known as exosomes, Evox focuses on creating innovative drug delivery systems that utilize nucleic acids and proteins. This technology allows for targeted delivery to specific organs, including the brain and central nervous system, addressing limitations often encountered with traditional therapies. Evox's proprietary methods for modifying exosomes enhance their ability to transport therapeutic agents effectively, thereby improving treatment options for patients with limited alternatives. The company is supported by a strong intellectual property portfolio and investments from leading life sciences venture capital groups, positioning it as a leader in the emerging field of exosome-based therapeutics.

Genomics

Series B in 2018
Genomics plc is focused on transforming healthcare through advanced genomic analysis. The company employs sophisticated methodologies to analyze large integrated datasets of genomic and phenotypic information, aiming to enhance understanding of human biology. By leveraging genetic inference technology, Genomics plc seeks to identify new drug targets for serious diseases and assess individual disease risk. Their analytical platform enables the exploration of genomic sequence data, providing valuable insights that support pharmaceutical companies in reducing risks associated with drug development. This approach not only aims to improve healthcare outcomes but also sets a standard for how organizations and patients can benefit from genomic data.
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