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ScienceIO develops a biomedical language platform to transform complex medical text into usable data and actionable insights. It detects and extracts biomedical terms, clinical variables, and medical codes in the text links complex information to make actionable data, and connects medical concepts to perform powerful queries. ScienceIO was established in 2019 by Gaurav Kaushik and Will Manidis in Massachusetts, United States.

MainStreet Work, Inc. operates a Software-as-a-Service (SaaS) platform designed to assist startups in identifying, filing, and claiming government incentives, tax credits, deductions, and stimulus programs. Founded in 2019 and based in San Jose, California, the platform connects to a company's payroll system to gather necessary data for qualifying for various programs and estimating potential financial benefits. MainStreet serves a range of companies, from bootstrapped to those in Series C funding, across multiple industries including software, hardware, biopharma, biotech, aerospace, materials, and manufacturing. The company charges a flat success fee of 20% upon the disbursement of incentives. By automating the identification and management of tax credits and legal workflows, MainStreet helps clients save time and reduce expenses.

Skydio is a drone manufacturer that uses artificial intelligence to create flying drones that are used by consumers, enterprises, and government customers. It develops AI-powered drones to deliver the power and flying cameras without the complexity. The company's drones use an array of cameras and proprietary computer vision technology to recognize, avoid objects in real-time, and predict into the future to make intelligent decisions, enabling users by flying themselves through the most demanding tasks or keeping them safe from obstacles when they want to take control. The company's debut drone, the R1, could track a target and film them while avoiding obstacles without any human intervention required. Then the company released the Skydio 2 in 2019, its second drone, cutting off more than half the price while improving it its autonomous tracking and video capabilities. Its flagship product, the X2, is equipped with seven cameras, 100x zoom, night vision, and promises to turn ordinary users into expert pilots thanks to its self-piloting abilities. It is backed by top investors and strategic partners including Andreessen Horowitz, Linse Capital, Next47, IVP, Playground, NVIDIA, and UP.Partners.

Pinch makes it easy to build its clients' credit history just by paying their rent. For no extra money, Pinch helps you beef up your credit score without going into debt. Not too long ago, paying rent didn’t have much to do with your credit score. Of course, not paying rent could always (and still can) damage your credit score. But what happens when you pay your rent on time? Legally speaking, absolutely nothing. Nada. The good news? Credit bureaus and credit scoring companies are realizing that those who can pay rent on time month after month are likely to also handle credit responsibly, and things are changing in America. Studies have shown that after reporting rent, 100% of tenants who were previously unscorable had a credit score. And almost 3/4 of those studied experienced a credit score increase.

Enzyme is building software to help life sciences companies with FDA approval and regulatory compliance. Using Enzyme’s software, those companies can avoid spending money on costly consultants which in turn can reduce their compliance costs by up to 50 percent. Since 10 percent of all personnel in biopharma and life sciences companies are related to regulatory issues, it can lower headcount as well. Perhaps most importantly, Enzyme can also make it easier and faster for those companies to bring their products to market.

Osmo Systems is making low-cost, low-maintenance online water quality monitoring systems for fish farms.