Peregrine Ventures

Lutris Pharma is a biopharmaceutical company based in Tel Aviv-Yafo, Israel, founded in 2015. The company focuses on developing therapeutic drugs aimed at enhancing the effectiveness of anti-cancer therapies. Its lead product, LUT014, is a proprietary small molecule B-Raf inhibitor designed to facilitate the administration of epidermal growth factor receptor (EGFR) inhibitors. This innovative approach helps mitigate the common cutaneous side effects associated with EGFR treatments, thereby improving the overall quality of life for patients undergoing cancer therapy.

Variantyx Inc. is a biotechnology company based in Framingham, Massachusetts, founded in 2014. The company specializes in diagnostic testing for rare disorders through its whole genome sequencing (WGS) platform, known as Genomic Unity®. This innovative test analyzes a single patient sample to identify and report all major variant types, including small sequence changes, structural variants, mitochondrial variants, and short tandem repeat expansions. By providing a comprehensive approach to genetic testing, Variantyx eliminates the need for traditional, step-wise genetic testing methods. The platform is designed to generate clinical reports that help hospitals and commercial laboratories accurately understand a patient's genetic makeup, leading to improved diagnosis and optimized treatment recommendations for inherited disorders.

Blue White Robotics specializes in transforming agriculture through autonomous technology. The company offers a comprehensive platform that enhances both air and ground robot fleets, enabling seamless management and optimization. By leveraging remote sensing and artificial intelligence, Blue White Robotics provides farmers with in-field data to improve productivity and farm economics. Their solutions aim to enhance efficiency and safety while delivering actionable insights that contribute to a return on investment from the outset. The company's focus is on facilitating the easy and safe adoption of autonomy in agriculture, ultimately helping growers maximize productivity and reduce operational costs.

Variantyx Inc. is a biotechnology company based in Framingham, Massachusetts, founded in 2014. The company specializes in diagnostic testing for rare disorders through its whole genome sequencing (WGS) platform, known as Genomic Unity®. This innovative test analyzes a single patient sample to identify and report all major variant types, including small sequence changes, structural variants, mitochondrial variants, and short tandem repeat expansions. By providing a comprehensive approach to genetic testing, Variantyx eliminates the need for traditional, step-wise genetic testing methods. The platform is designed to generate clinical reports that help hospitals and commercial laboratories accurately understand a patient's genetic makeup, leading to improved diagnosis and optimized treatment recommendations for inherited disorders.

BioProtect Ltd. is an international medical device startup focused on developing and commercializing biodegradable balloon spacers designed to protect normal tissue during cancer radiation therapy. The company's flagship product, the ProSpace balloon spacer, has demonstrated superior efficacy and safety in safeguarding the rectum during radiation treatment for prostate cancer. This innovative technology significantly reduces the risk of serious and chronic side effects associated with radiation, while enhancing tumor control. Founded in 2004 and headquartered in Israel, BioProtect also operates subsidiaries in Germany and the United States, aiming to address unmet clinical needs in the growing radiotherapy spacers market with its platform of biodegradable implantable balloons.

Althea Medical, established in 2020 in Tel Aviv, Israel, focuses on developing catheter devices for the treatment of patients suffering from pulmonary embolism (PE), including both massive and sub-massive cases. The company's innovative catheter-based solution combines the effectiveness of large bore thrombectomy with a user-friendly delivery mechanism that reduces patient risks. This mechanical clot removal system is designed to efficiently capture and eliminate thrombus, allowing physicians to swiftly access blocked areas and alleviate clot burden, thereby enhancing hemodynamic stability in affected patients.

DataMesh Group delivers integrated payment capabilities and valuable customer insights through bespoke payment and data processing solutions. The company offers financial payment systems software, infrastructure, and data analytics products. It enables retailers to design the customer experience they want to provide by providing the technology they want to deploy and creating a commerce and data hub that merchants, acquirers, card schemes, and third parties can use to achieve better business outcomes.

Nectin Therapeutics Ltd., founded in 2017 and based in Jerusalem, Israel, specializes in the development of monoclonal antibodies targeting members of the Nectin family of receptors and ligands. These antibodies are designed to address immune checkpoint mechanisms that play a crucial role in cancer immunotherapy. By focusing on both solid and hematological malignancies, Nectin Therapeutics aims to create therapies that can overcome the inhibitory pathways utilized by tumors, thereby enhancing the ability of immune cells to eradicate cancer cells. The company's innovative approach seeks to improve patient outcomes in cancer treatment.

Cordio Medical LTD. is a company based in Or Yehuda, Israel, founded in 2013, that specializes in developing a mobile application aimed at monitoring patients with congestive heart failure. The application utilizes advanced speech processing technology to analyze a patient's voice, allowing for near real-time monitoring and early detection of health deterioration. By transcribing patients' speech, the platform assists healthcare providers in identifying potential issues, enabling them to intervene before conditions worsen and prevent unnecessary hospitalizations. This innovative approach emphasizes patient well-being and aims to facilitate care management while allowing patients to remain at home.

Variantyx Inc. is a biotechnology company based in Framingham, Massachusetts, founded in 2014. The company specializes in diagnostic testing for rare disorders through its whole genome sequencing (WGS) platform, known as Genomic Unity®. This innovative test analyzes a single patient sample to identify and report all major variant types, including small sequence changes, structural variants, mitochondrial variants, and short tandem repeat expansions. By providing a comprehensive approach to genetic testing, Variantyx eliminates the need for traditional, step-wise genetic testing methods. The platform is designed to generate clinical reports that help hospitals and commercial laboratories accurately understand a patient's genetic makeup, leading to improved diagnosis and optimized treatment recommendations for inherited disorders.

Blue White Robotics specializes in transforming agriculture through autonomous technology. The company offers a comprehensive platform that enhances both air and ground robot fleets, enabling seamless management and optimization. By leveraging remote sensing and artificial intelligence, Blue White Robotics provides farmers with in-field data to improve productivity and farm economics. Their solutions aim to enhance efficiency and safety while delivering actionable insights that contribute to a return on investment from the outset. The company's focus is on facilitating the easy and safe adoption of autonomy in agriculture, ultimately helping growers maximize productivity and reduce operational costs.

BrainQ is a company founded in 2016 and headquartered in Jerusalem, Israel, that focuses on developing precision neurology therapies for individuals with neuro disorders. The company operates a neuro recovery platform that employs a brain-computer interface (BCI) approach to target damaged neuronal networks. By integrating machine learning algorithms with neuroscience, BrainQ extracts biological insights that inform the creation of tailored therapies. These innovations aim to facilitate neuro recovery and enhance the quality of life for patients, enabling them to live more independent and fulfilling lives.

Aleph Farms Limited, based in Ashdod, Israel, is a food technology company focused on sustainable animal product innovation through cellular agriculture. Founded in 2017, Aleph Farms has pioneered the development of lab-cultured meat, notably unveiling the world’s first cultivated thin-cut steak in 2018 and the first cultivated ribeye steak in 2021. The company utilizes proprietary three-dimensional bioprinting technology to grow animal products directly from non-genetically modified cells, thereby eliminating the need for animal slaughter. Under its product brand, Aleph Cuts, Aleph Farms is set to launch the Petit Steak, which is produced from premium Angus cow cells. The company has been recognized for its commitment to climate leadership and sustainability, receiving accolades from the World Economic Forum and the United Nations for its net zero commitment made in 2020.

Aleph Farms Limited, based in Ashdod, Israel, is a food technology company focused on sustainable animal product innovation through cellular agriculture. Founded in 2017, Aleph Farms has pioneered the development of lab-cultured meat, notably unveiling the world’s first cultivated thin-cut steak in 2018 and the first cultivated ribeye steak in 2021. The company utilizes proprietary three-dimensional bioprinting technology to grow animal products directly from non-genetically modified cells, thereby eliminating the need for animal slaughter. Under its product brand, Aleph Cuts, Aleph Farms is set to launch the Petit Steak, which is produced from premium Angus cow cells. The company has been recognized for its commitment to climate leadership and sustainability, receiving accolades from the World Economic Forum and the United Nations for its net zero commitment made in 2020.

KAHR Medical Ltd. is an immuno-oncology drug development company based in Jerusalem, Israel, founded in 2005. The company focuses on creating fusion protein pharmaceuticals aimed at treating cancer and autoimmune diseases. KAHR develops innovative drugs such as DSP105 and DSP106, which facilitate T-cell mediated tumor destruction, and DSP107, which targets CD47 tumors to activate phagocytes while delivering an immune costimulatory signal. Utilizing a unique platform of multifunctional immuno-recruitment proteins, KAHR's technology aims to enhance immune system recognition of cancer cells, thereby addressing the challenge of cancer evasion. This approach represents a significant advancement in protein-based pharmaceuticals, expanding treatment options for patients facing these serious health conditions.

Ribon Therapeutics, Inc. is a biotechnology company based in Lexington, Massachusetts, focused on developing novel cancer therapies that target monoPARP proteins, which are essential regulators of cancer survival mechanisms. Established in 2015, Ribon is leveraging insights from its scientific founders and an experienced management team to create a proprietary drug discovery platform aimed at understanding the molecular actions and biological functions of monoPARPs. This platform enables the development of small molecule inhibitors designed to disrupt cancer cells' abilities to withstand stress, potentially leading to innovative treatments for cancer and other diseases. The company is supported by notable life science investors, positioning it for growth in the biopharmaceutical sector.

Memic Innovative Surgery develops and delivers robotic surgical solutions designed to enable otherwise infeasible surgical procedures. Its first offering facilitates a variety of robotic gynecological procedures via a vaginal approach, expanding the feasibility of vaginal surgery to the vast majority of cases. Its robotic technology consists of miniature and humanoid-shaped articulated arms that mimic human dexterity while surpassing human flexibility. The robotic arms are controllable via various proprietary control consoles to maintain natural control of the arms, allowing surgeons to operate precisely in tight anatomical spaces with decreased risk to nearby organs and tissue.

OutSense develops an IoT medical device aimed at early illness detection and wellness monitoring through the analysis of human waste. Utilizing innovative imaging technologies, the device detects tiny quantities of blood mixed with stool directly within a standard toilet bowl. This capability allows for the generation of daily medical status reports for individuals, alerting caregivers to health deviations and potential abnormalities. The primary focus of OutSense is the prevention of colorectal cancer by identifying hidden blood in stool, a well-established screening method that traditionally requires sending samples to specialized laboratories. By integrating this technology with a mobile application, OutSense aims to enhance proactive health management and improve early diagnosis.

BioProtect Ltd. is an international medical device startup focused on developing and commercializing biodegradable balloon spacers designed to protect normal tissue during cancer radiation therapy. The company's flagship product, the ProSpace balloon spacer, has demonstrated superior efficacy and safety in safeguarding the rectum during radiation treatment for prostate cancer. This innovative technology significantly reduces the risk of serious and chronic side effects associated with radiation, while enhancing tumor control. Founded in 2004 and headquartered in Israel, BioProtect also operates subsidiaries in Germany and the United States, aiming to address unmet clinical needs in the growing radiotherapy spacers market with its platform of biodegradable implantable balloons.

Blue White Robotics specializes in transforming agriculture through autonomous technology. The company offers a comprehensive platform that enhances both air and ground robot fleets, enabling seamless management and optimization. By leveraging remote sensing and artificial intelligence, Blue White Robotics provides farmers with in-field data to improve productivity and farm economics. Their solutions aim to enhance efficiency and safety while delivering actionable insights that contribute to a return on investment from the outset. The company's focus is on facilitating the easy and safe adoption of autonomy in agriculture, ultimately helping growers maximize productivity and reduce operational costs.

Hairstetics Ltd. is an innovative medical device company based in Omer, Israel, founded in 2010. The company specializes in the development, manufacturing, and marketing of advanced hair restoration devices. Hairstetics offers a range of solutions, including surgical hair transplantation and non-surgical methods, alongside customizable hair implantation services that allow for various colors, styles, and lengths. Their products are designed to simplify the hair implantation procedure, reduce recovery time, and deliver enhanced aesthetic results at a more affordable cost compared to traditional techniques. Through these offerings, Hairstetics aims to provide effective solutions for individuals experiencing hair loss.

Levation Pharma focuses on developing innovative treatments in aesthetic dermatology. The company is known for its topical oxymetazoline product, which is designed for cosmetic eye lifts. This product features a drying aqueous gel that utilizes a transdermal formulation of oxymetazoline. It specifically targets the treatment of droopy upper eyelids, medically referred to as ptosis or blepharoptosis. By enabling patients to raise their upper lids, this product not only enhances the visual fields but also improves the overall appearance of the eyes.

Atrial Fibrillation treatment using cryo

Catheter procedure for LAA (left atrial appendage) closure, for Atrial fibrillation patients

Payzday is a risk management solution provider based in Tel Aviv, Israel, established in 2017. The company specializes in analyzing the risk levels of merchants selling online through marketplaces. By leveraging advanced technologies such as big data, artificial intelligence, and predictive analytics, Payzday creates significant visibility into the risk associated with these merchants. Its approach extends beyond initial onboarding assessments, offering continuous monitoring that enables near real-time predictions of any potentially unlawful, risky, or unstable situations involving merchants. This innovative methodology allows financial institutions to make informed decisions and provide necessary financing solutions to online sellers, ultimately aiming to enhance their access to capital.

SinuSafe Medical, founded in 2014 and based in Tel Aviv, Israel, focuses on developing a nano-debrider device aimed at treating sinus-related issues without the need for surgical intervention. This innovative device allows for sinus irrigation and aspiration by implanting bone between the lining and the maxillary sinus, providing a non-invasive solution for patients suffering from chronic sinusitis. By enabling sinus lavage in a physician's office, SinuSafe Medical offers ear, nose, and throat (ENT) specialists a means to deliver immediate relief to their patients, thereby improving their quality of life.

Restore Medical is a medical device company focused on treating congestive heart failure, specifically targeting patients with left ventricle failure. Founded in 2016 and based in Or Yehuda, Israel, the company offers ContraBand, a catheter-delivered implant designed for placement in the pulmonary arteries. This innovative device aims to enhance left ventricle ejection fraction, decrease mitral regurgitation, and restore favorable ventricular geometry. By improving patient outcomes, Restore Medical's solutions contribute to a better quality of life and aim to reduce the rates of hospital readmission among affected individuals.

Raziel Therapeutics Ltd. is a pharmaceutical company based in Rehovot, Israel, founded in 2012. The company specializes in the development of RZL-012, a novel synthetic small molecule designed for injectable treatment into subcutaneous fat. This treatment leads to fat cell death at the injection site, resulting in a significant and long-lasting reduction in fat tissue. Raziel Therapeutics is engaged in various clinical trials focusing on fat-related conditions and aesthetic applications, aiming to provide effective solutions for obesity and disorders such as Dercum's disease. The innovative approach of Raziel Therapeutics offers healthcare professionals a non-invasive option for achieving substantial fat reduction for their patients.

Raziel Therapeutics Ltd. is a pharmaceutical company based in Rehovot, Israel, founded in 2012. The company specializes in the development of RZL-012, a novel synthetic small molecule designed for injectable treatment into subcutaneous fat. This treatment leads to fat cell death at the injection site, resulting in a significant and long-lasting reduction in fat tissue. Raziel Therapeutics is engaged in various clinical trials focusing on fat-related conditions and aesthetic applications, aiming to provide effective solutions for obesity and disorders such as Dercum's disease. The innovative approach of Raziel Therapeutics offers healthcare professionals a non-invasive option for achieving substantial fat reduction for their patients.

Magneto Thrombectomy is a medical device company focused on developing innovative thrombectomy devices for the treatment of ischemic stroke. Their technology employs electric attractive forces to facilitate the efficient and safe retrieval of various types of blood clots, ranging from large proximal to small distal locations within the vascular system. This method minimizes radial forces exerted on blood vessels, allowing access to the most distal regions of the brain. By enabling medical professionals to perform thrombectomy procedures effectively, Magneto Thrombectomy aims to optimize patient outcomes for those diagnosed with acute ischemic stroke.

Medical device company treating the mitral valve

Roby.ai offers an artificial intelligence assistant tailored for rental agencies and property managers, designed to streamline property management tasks with minimal human intervention. The platform automates various time-consuming and manual activities, allowing property managers to enhance efficiency and improve compliance while significantly reducing costs. By utilizing push notifications via SMS and email, Roby.ai facilitates user engagement throughout the rental process, making interactions smoother for both managers and clients. This bespoke automation software addresses the complexities of property management, enabling users to focus on strategic activities rather than mundane tasks. Overall, Roby.ai aims to transform the rental management landscape by providing a comprehensive solution that increases operational efficiency and effectiveness.

Aleph Farms Limited, based in Ashdod, Israel, is a food technology company focused on sustainable animal product innovation through cellular agriculture. Founded in 2017, Aleph Farms has pioneered the development of lab-cultured meat, notably unveiling the world’s first cultivated thin-cut steak in 2018 and the first cultivated ribeye steak in 2021. The company utilizes proprietary three-dimensional bioprinting technology to grow animal products directly from non-genetically modified cells, thereby eliminating the need for animal slaughter. Under its product brand, Aleph Cuts, Aleph Farms is set to launch the Petit Steak, which is produced from premium Angus cow cells. The company has been recognized for its commitment to climate leadership and sustainability, receiving accolades from the World Economic Forum and the United Nations for its net zero commitment made in 2020.

mPharma is a healthcare company focused on enhancing access to affordable medications in emerging markets. Founded in 2013 by Gregory Rockson, Daniel Shoukimas, and James Finucane, mPharma collaborates with drug manufacturers, insurance providers, financial institutions, and governments to streamline the delivery of prescription drugs to consumers. The company offers a pharmaceutical data analytics platform that assists pharmacies in managing their inventory, prescribing medications, and reporting adverse drug reactions. By ensuring that high-quality chronic disease medications are consistently available at sustainable prices, mPharma aims to improve health outcomes for patients, doctors, and pharmacists alike.

Magnisity is a technology company founded in 2018 in Or Yehuda, Israel, by Benny Greenburg and Ron Barak. It specializes in developing innovative solutions for minimally invasive surgeries through a unique platform that integrates hardware design, software development, precise mechanics, and engineering. By leveraging advanced algorithms, Magnisity aims to enhance the capabilities of medical devices, enabling surgeons to address complex challenges in endoluminal interventions effectively. The company's focus on creating tools for both surgeons and patients positions it as a key player in the evolution of minimally invasive medicine.

Catheter procedure for LAA (left atrial appendage) closure, for Atrial fibrillation patients

Heracure is a company focused on the development of medical instruments for the selective mechanical resection of fibroids through natural orifice access, specifically via a transvaginal approach. The company is creating an innovative control system designed to facilitate the safe removal of large uteri, providing healthcare professionals with an alternative to traditional abdominal surgery. This approach aims to enhance patient outcomes by minimizing invasiveness and recovery time associated with fibroid treatments.

Kymera Labs specializes in synthetic data generation through an innovative algebra-based mathematical model that ensures the preservation of statistical quality and data features while safeguarding actual data. The company's software allows clients to synthesize various data types, including scalars, labels, addresses, and dates, all while maintaining data dependencies and minimizing bias. This approach enables the generation of tailored synthetic data for different verticals, ensuring compliance with privacy laws and enhancing data utility. By offering a risk-free solution, Kymera Labs effectively addresses the challenges associated with data security and privacy in data-driven environments.

Payzday is a risk management solution provider based in Tel Aviv, Israel, established in 2017. The company specializes in analyzing the risk levels of merchants selling online through marketplaces. By leveraging advanced technologies such as big data, artificial intelligence, and predictive analytics, Payzday creates significant visibility into the risk associated with these merchants. Its approach extends beyond initial onboarding assessments, offering continuous monitoring that enables near real-time predictions of any potentially unlawful, risky, or unstable situations involving merchants. This innovative methodology allows financial institutions to make informed decisions and provide necessary financing solutions to online sellers, ultimately aiming to enhance their access to capital.

Magneto Thrombectomy is a medical device company focused on developing innovative thrombectomy devices for the treatment of ischemic stroke. Their technology employs electric attractive forces to facilitate the efficient and safe retrieval of various types of blood clots, ranging from large proximal to small distal locations within the vascular system. This method minimizes radial forces exerted on blood vessels, allowing access to the most distal regions of the brain. By enabling medical professionals to perform thrombectomy procedures effectively, Magneto Thrombectomy aims to optimize patient outcomes for those diagnosed with acute ischemic stroke.

Atrial Fibrillation treatment using cryo

Restore Medical Solutions, Inc. is a medical device company based in Memphis, Tennessee, founded in 2012. The company specializes in manufacturing modular sterilization tray systems designed for use in hospitals and surgery centers. These systems aim to reduce the risk of surgical site infections by minimizing contamination from medical instruments. By enhancing efficiency and safety in healthcare settings, Restore Medical Solutions helps surgical departments improve the quality of care while also lowering costs. The innovative design of its products contributes to better operational productivity and supports the overall goal of delivering high-standard healthcare.

Memic Innovative Surgery develops and delivers robotic surgical solutions designed to enable otherwise infeasible surgical procedures. Its first offering facilitates a variety of robotic gynecological procedures via a vaginal approach, expanding the feasibility of vaginal surgery to the vast majority of cases. Its robotic technology consists of miniature and humanoid-shaped articulated arms that mimic human dexterity while surpassing human flexibility. The robotic arms are controllable via various proprietary control consoles to maintain natural control of the arms, allowing surgeons to operate precisely in tight anatomical spaces with decreased risk to nearby organs and tissue.

Hairstetics Ltd. is an innovative medical device company based in Omer, Israel, founded in 2010. The company specializes in the development, manufacturing, and marketing of advanced hair restoration devices. Hairstetics offers a range of solutions, including surgical hair transplantation and non-surgical methods, alongside customizable hair implantation services that allow for various colors, styles, and lengths. Their products are designed to simplify the hair implantation procedure, reduce recovery time, and deliver enhanced aesthetic results at a more affordable cost compared to traditional techniques. Through these offerings, Hairstetics aims to provide effective solutions for individuals experiencing hair loss.

CliClap LTD is a content marketing utility based in Kfar Saba, Israel, founded in 2016. The company offers an AI-powered platform designed to enhance audience engagement and brand visibility by tracking and optimizing shared content. Its solution supports businesses in generating leads and increasing traffic through effective content marketing strategies. By guiding visitors through personalized content journeys, CliClap helps nurture qualified leads without requiring extensive management. The platform integrates seamlessly with existing marketing automation, CRM, and social media management tools, allowing marketing teams to operate more efficiently and significantly boost conversion rates. Overall, CliClap aims to drive business goals by providing actionable insights and enhancing user interaction with content.

CliClap LTD is a content marketing utility based in Kfar Saba, Israel, founded in 2016. The company offers an AI-powered platform designed to enhance audience engagement and brand visibility by tracking and optimizing shared content. Its solution supports businesses in generating leads and increasing traffic through effective content marketing strategies. By guiding visitors through personalized content journeys, CliClap helps nurture qualified leads without requiring extensive management. The platform integrates seamlessly with existing marketing automation, CRM, and social media management tools, allowing marketing teams to operate more efficiently and significantly boost conversion rates. Overall, CliClap aims to drive business goals by providing actionable insights and enhancing user interaction with content.

DOKKA operates a cloud-based software platform designed to automate the invoice processing workflow for bookkeepers and accountants. Utilizing proprietary artificial intelligence and visual recognition technology, DOKKA streamlines the documentation process, significantly reducing the time and costs associated with manual data entry. The platform is compatible with a wide range of accounting systems, seamlessly integrating with both major ERP platforms and lesser-known systems. DOKKA's technology is particularly beneficial for small businesses and contractors, allowing them to enhance their accounting operations while minimizing errors. The deployment of the software typically takes between 7 to 14 days, offering both done-for-you and collaborative API integration options to accommodate various user needs.

Levation Pharma focuses on developing innovative treatments in aesthetic dermatology. The company is known for its topical oxymetazoline product, which is designed for cosmetic eye lifts. This product features a drying aqueous gel that utilizes a transdermal formulation of oxymetazoline. It specifically targets the treatment of droopy upper eyelids, medically referred to as ptosis or blepharoptosis. By enabling patients to raise their upper lids, this product not only enhances the visual fields but also improves the overall appearance of the eyes.

Payzday is a risk management solution provider based in Tel Aviv, Israel, established in 2017. The company specializes in analyzing the risk levels of merchants selling online through marketplaces. By leveraging advanced technologies such as big data, artificial intelligence, and predictive analytics, Payzday creates significant visibility into the risk associated with these merchants. Its approach extends beyond initial onboarding assessments, offering continuous monitoring that enables near real-time predictions of any potentially unlawful, risky, or unstable situations involving merchants. This innovative methodology allows financial institutions to make informed decisions and provide necessary financing solutions to online sellers, ultimately aiming to enhance their access to capital.

Cordio Medical LTD. is a company based in Or Yehuda, Israel, founded in 2013, that specializes in developing a mobile application aimed at monitoring patients with congestive heart failure. The application utilizes advanced speech processing technology to analyze a patient's voice, allowing for near real-time monitoring and early detection of health deterioration. By transcribing patients' speech, the platform assists healthcare providers in identifying potential issues, enabling them to intervene before conditions worsen and prevent unnecessary hospitalizations. This innovative approach emphasizes patient well-being and aims to facilitate care management while allowing patients to remain at home.

Cordio Medical LTD. is a company based in Or Yehuda, Israel, founded in 2013, that specializes in developing a mobile application aimed at monitoring patients with congestive heart failure. The application utilizes advanced speech processing technology to analyze a patient's voice, allowing for near real-time monitoring and early detection of health deterioration. By transcribing patients' speech, the platform assists healthcare providers in identifying potential issues, enabling them to intervene before conditions worsen and prevent unnecessary hospitalizations. This innovative approach emphasizes patient well-being and aims to facilitate care management while allowing patients to remain at home.

Digma Medical is a clinical stage medical device company established in 2013, focused on innovating treatments for Type-2 Diabetes and related metabolic syndromes, including NASH. The company is developing the DiaGone™, an endoscopic and disposable device that employs advanced laser technology to treat the duodenum without the need for an implant. The Duodenal Glycemic Control™ procedure, which lasts approximately 30 minutes, allows gastroenterologists to use the DiaGone™ to enhance the body's ability to regulate glucose levels. This approach aims to offer patients the potential for long-term remission from Type-2 Diabetes and other metabolic conditions, thereby improving their overall quality of life and health outcomes. Supported by prominent venture capital firms, Digma Medical is dedicated to advancing effective therapies for diabetes management.

Rise.ai operates a strategic re-engagement platform that enables brands and retailers to utilize a unique currency system, including gift cards and store credits. By leveraging artificial intelligence, the company helps merchants enhance customer retention and boost average spending. The platform manages the entire re-engagement cycle, offering features such as loyalty cards, rewards, and refunds. Additionally, it allows users to send gifts, such as drinks and treats, to friends, thereby facilitating social gifting experiences. Through these services, Rise.ai aims to strengthen customer relationships and drive revenue growth for eCommerce agencies, brands, and merchants.

Eve Pharma is a preclinical drug delivery company focused on developing treatments for bacterial vaginosis, a condition commonly affecting women's health. Specializing in gynecology, the firm is working on a lead product designed to identify the source of vaginal infections, thereby facilitating easier diagnosis and treatment for healthcare providers. Through its innovative approach, Eve Pharma aims to enhance the clinical management of this condition, improving patient outcomes in the field of gynecological health.

OutSense develops an IoT medical device aimed at early illness detection and wellness monitoring through the analysis of human waste. Utilizing innovative imaging technologies, the device detects tiny quantities of blood mixed with stool directly within a standard toilet bowl. This capability allows for the generation of daily medical status reports for individuals, alerting caregivers to health deviations and potential abnormalities. The primary focus of OutSense is the prevention of colorectal cancer by identifying hidden blood in stool, a well-established screening method that traditionally requires sending samples to specialized laboratories. By integrating this technology with a mobile application, OutSense aims to enhance proactive health management and improve early diagnosis.

Magneto Thrombectomy is a medical device company focused on developing innovative thrombectomy devices for the treatment of ischemic stroke. Their technology employs electric attractive forces to facilitate the efficient and safe retrieval of various types of blood clots, ranging from large proximal to small distal locations within the vascular system. This method minimizes radial forces exerted on blood vessels, allowing access to the most distal regions of the brain. By enabling medical professionals to perform thrombectomy procedures effectively, Magneto Thrombectomy aims to optimize patient outcomes for those diagnosed with acute ischemic stroke.

NeuroApplied Ltd. is a marketing research company based in Hadera, Israel, founded in June 2016. The firm specializes in customer-focused marketing by exploring the collective subconscious of consumers. Utilizing machine-learning analytics and neural-network computing, NeuroApplied's platform incorporates online picture games to collect data that reflects customers' associative subconscious responses. This SaaS-based platform features an intuitive dashboard that presents insights in a visually engaging and nonintrusive manner. The services offered include brand equity assessment, tracking of brand properties, crisis management, and decision support, all designed to help brand managers understand and quantify consumer perceptions effectively.

Eximo Medical Ltd. is an Israeli company specializing in hybrid catheter technology aimed at improving tissue resection in vascular and gastrointestinal endoluminal applications. Founded in 2012 and based in Modi'in-Maccabim-Re'ut, the company has developed the CatHI™, a proprietary single-use hybrid catheter that integrates optical fibers for delivering short laser pulses with a blunt mechanical knife. This innovative design enhances the safety and effectiveness of procedures, particularly in lead extraction and the treatment of peripheral artery disease, by minimizing the risk of vessel perforation. As of October 2019, Eximo Medical operates as a subsidiary of AngioDynamics, Inc.

Restore Medical Solutions, Inc. is a medical device company based in Memphis, Tennessee, founded in 2012. The company specializes in manufacturing modular sterilization tray systems designed for use in hospitals and surgery centers. These systems aim to reduce the risk of surgical site infections by minimizing contamination from medical instruments. By enhancing efficiency and safety in healthcare settings, Restore Medical Solutions helps surgical departments improve the quality of care while also lowering costs. The innovative design of its products contributes to better operational productivity and supports the overall goal of delivering high-standard healthcare.

mPharma is a healthcare company focused on enhancing access to affordable medications in emerging markets. Founded in 2013 by Gregory Rockson, Daniel Shoukimas, and James Finucane, mPharma collaborates with drug manufacturers, insurance providers, financial institutions, and governments to streamline the delivery of prescription drugs to consumers. The company offers a pharmaceutical data analytics platform that assists pharmacies in managing their inventory, prescribing medications, and reporting adverse drug reactions. By ensuring that high-quality chronic disease medications are consistently available at sustainable prices, mPharma aims to improve health outcomes for patients, doctors, and pharmacists alike.

SinuSafe Medical, founded in 2014 and based in Tel Aviv, Israel, focuses on developing a nano-debrider device aimed at treating sinus-related issues without the need for surgical intervention. This innovative device allows for sinus irrigation and aspiration by implanting bone between the lining and the maxillary sinus, providing a non-invasive solution for patients suffering from chronic sinusitis. By enabling sinus lavage in a physician's office, SinuSafe Medical offers ear, nose, and throat (ENT) specialists a means to deliver immediate relief to their patients, thereby improving their quality of life.

mPharma is a healthcare company focused on enhancing access to affordable medications in emerging markets. Founded in 2013 by Gregory Rockson, Daniel Shoukimas, and James Finucane, mPharma collaborates with drug manufacturers, insurance providers, financial institutions, and governments to streamline the delivery of prescription drugs to consumers. The company offers a pharmaceutical data analytics platform that assists pharmacies in managing their inventory, prescribing medications, and reporting adverse drug reactions. By ensuring that high-quality chronic disease medications are consistently available at sustainable prices, mPharma aims to improve health outcomes for patients, doctors, and pharmacists alike.

Memic Innovative Surgery develops and delivers robotic surgical solutions designed to enable otherwise infeasible surgical procedures. Its first offering facilitates a variety of robotic gynecological procedures via a vaginal approach, expanding the feasibility of vaginal surgery to the vast majority of cases. Its robotic technology consists of miniature and humanoid-shaped articulated arms that mimic human dexterity while surpassing human flexibility. The robotic arms are controllable via various proprietary control consoles to maintain natural control of the arms, allowing surgeons to operate precisely in tight anatomical spaces with decreased risk to nearby organs and tissue.

Memic Innovative Surgery develops and delivers robotic surgical solutions designed to enable otherwise infeasible surgical procedures. Its first offering facilitates a variety of robotic gynecological procedures via a vaginal approach, expanding the feasibility of vaginal surgery to the vast majority of cases. Its robotic technology consists of miniature and humanoid-shaped articulated arms that mimic human dexterity while surpassing human flexibility. The robotic arms are controllable via various proprietary control consoles to maintain natural control of the arms, allowing surgeons to operate precisely in tight anatomical spaces with decreased risk to nearby organs and tissue.

Evolero Ltd. specializes in event management software solutions tailored for event organizers and meeting planners. Founded in 2011 and headquartered in Herzliya, Israel, the company provides a comprehensive platform that facilitates online conference planning and organization. Evolero's software enables users to sell tickets online, manage event ticketing and registration, and offers sponsors advanced marketing tools. Additionally, it equips attendees with networking capabilities, all within a single platform. By integrating various functionalities, Evolero supports meeting planners and congress organizers in creating effective event websites and enhancing social media engagement for improved networking opportunities.

Cordio Medical LTD. is a company based in Or Yehuda, Israel, founded in 2013, that specializes in developing a mobile application aimed at monitoring patients with congestive heart failure. The application utilizes advanced speech processing technology to analyze a patient's voice, allowing for near real-time monitoring and early detection of health deterioration. By transcribing patients' speech, the platform assists healthcare providers in identifying potential issues, enabling them to intervene before conditions worsen and prevent unnecessary hospitalizations. This innovative approach emphasizes patient well-being and aims to facilitate care management while allowing patients to remain at home.

Yotta Green offers an innovative smart home system that focuses on improving energy efficiency, comfort, and safety through advanced monitoring technologies. By analyzing household power consumption and learning consumer behavior patterns, the system provides valuable insights into energy usage. It alerts users to potential energy waste and electrical hazards, such as fires, and can automatically turn off unused lights and appliances. Additionally, the system can take proactive measures, like lowering blinds before a storm, to enhance home safety. Yotta Green's user-friendly interface, accessible via a smartphone app along with touch and gesture activation devices, ensures maximum convenience for homeowners seeking to optimize their energy consumption and maintain a secure living environment.

ShapeDo Ltd. is a software company based in Modi'in-Maccabim-Re'ut, Israel, founded in 2014. It specializes in developing solutions to manage the implications of plan changes in construction projects. The company's cloud-based platform facilitates end-to-end management of these changes by organizing blueprints, comparing versions, and ensuring that all modifications are reflected in contracts, budgets, and agreements. ShapeDo's software aids in creating court-ready pricing reports, requests for information, and claims. The company has been involved in significant infrastructure projects, including airports, underground trains, hospitals, and data centers, and its solutions are also applicable to smaller commercial and residential projects.

Jobrain Ltd. is a Herzliya, Israel-based company that offers a cloud-based hiring software designed to streamline the recruitment process for HR professionals. The platform allows candidates to easily apply for jobs using mobile devices, while HR teams can quickly identify and hire the best talent. Jobrain provides an open marketplace that includes various talent acquisition services such as job post distribution, remote interviews, one-way video interviews, and candidate assessments. Additionally, it features a job search application that connects users to a network of recruiters, utilizing machine learning to match candidates with over 100,000 job opportunities worldwide, primarily in software development and small startups. By leveraging data science, Jobrain simplifies the hiring process, enabling clients to focus on essential tasks rather than administrative burdens.

NitiNotes is a company specializing in innovative medical technology, particularly for the field of gastroenterology. It has developed the EndoZip™, a fully automated gastroscopic suturing system designed to enhance the safety and simplicity of gastrointestinal suturing. This minimally invasive device enables gastroenterologists and surgeons to perform procedures that mimic laparoscopic sleeve gastrectomy, effectively creating a stomach volume restriction to assist patients with obesity in achieving weight loss. The system is intended for patients classified as obesity class I and II, providing an alternative for those who may not qualify for traditional bariatric surgery. By streamlining endoscopic gastroplasty procedures, NitiNotes aims to make effective weight-loss treatments more accessible to a broader range of patients.

Zuznow is a mobile application development company that specializes in adapting complex websites for optimal use on smartphones. Founded in 2009 and based in Israel, Zuznow's platform automatically analyzes the visual structure of desktop websites and transforms them for mobile devices. This capability allows businesses to implement effective mobile strategies for various applications, including B2B, B2C, and B2E. The platform streamlines the development process, enabling organizations to create secure mobile applications while significantly reducing time to market and lowering costs associated with setup and maintenance. Zuznow's clientele includes notable companies such as VentureBeat, HOOP, Newsgeek, and Baker Tilly.

Marketyze is a technology company specializing in semantic site search and online price comparison solutions, primarily serving the retail industry. Founded in December 2011 by Onn Manelson and Nave Ronen, the company is based in Israel. Marketyze's pricing intelligence software collects and examines pricing, market, and internal data to assess the impact of pricing events on sales performance. This analysis enables retailers to refine their pricing strategies, ultimately aiming to enhance both sales and profitability. Additionally, Marketyze provides a cloud-based platform that monitors and evaluates product prices among competitors, delivering essential pricing data and analytics to online retailers.

Evolero Ltd. specializes in event management software solutions tailored for event organizers and meeting planners. Founded in 2011 and headquartered in Herzliya, Israel, the company provides a comprehensive platform that facilitates online conference planning and organization. Evolero's software enables users to sell tickets online, manage event ticketing and registration, and offers sponsors advanced marketing tools. Additionally, it equips attendees with networking capabilities, all within a single platform. By integrating various functionalities, Evolero supports meeting planners and congress organizers in creating effective event websites and enhancing social media engagement for improved networking opportunities.

NLT SPINE is a clinical stage company focused on developing and marketing innovative Minimally Invasive Spinal Surgery (MISS) products aimed at treating degenerative spinal conditions. The company creates surgical instruments and implants designed to alleviate back pain and enhance surgical outcomes. By utilizing non-linear technology, NLT SPINE aims to revolutionize traditional open surgical practices, transitioning to techniques that promote safety and predictability through smaller surgical incisions. The commitment to improving patient care underscores the company's mission to deliver advanced solutions in spinal surgery.

ArTack Medical is a privately held medical device company based in Haifa, Israel, founded in 2013. The company specializes in developing innovative tools for the invasive surgery market, particularly focusing on hernia repair. ArTack Medical's flagship product is an articulated hernia mesh fixation device designed to facilitate both laparoscopic and open surgical procedures. This device is compatible with any currently available mesh and allows surgeons to maintain their standard techniques without modification. The company’s patented drive platform enables the delivery of torque through a 5mm shaft, enhancing the effectiveness and ease of surgical interventions.

Mend (previously known as WhiteSource) founded in 2011, Mend is the first application security platform that actually automates the process of fixing application vulnerabilities. Mend takes most of the burden off the developer, who doesn’t really need to become a security expert. That’s why our motto is: You code, we cure. Mend is used by more than 1000 customers worldwide, from all verticals and sizes, including 23% of Fortune 100 companies, as well as industry leaders such as Microsoft, IBM, Comcast, and many more. For more information, please visit www.mend.io

CartiHeal is a medical device company based in Kfar Sava, Israel, specializing in cartilage and bone regeneration. Founded in 2009, the company has developed the Agili-C implant, a cell-free and off-the-shelf solution designed to address focal articular cartilage and osteochondral defects. This innovative implant promotes the regeneration of hyaline cartilage and the underlying subchondral bone without the need for cells or growth factors, making it a significant advancement in the treatment of cartilage injuries. Given the limited natural healing capacity of hyaline cartilage, CartiHeal's technology offers a promising option for patients suffering from cartilage damage, which can lead to severe pain and disability if untreated. The Agili-C implant can be inserted using arthroscopic or minimally invasive techniques, facilitating faster rehabilitation and enhanced recovery outcomes for patients.

Peak-Dynamics is a research-driven technology company focused on enhancing the efficiency of water utility operations. It has developed PeakWater, a sophisticated software platform that integrates with existing SCADA systems to monitor and optimize energy usage and water delivery processes. The platform employs the Optimized Stochastic Search Algorithm (OSSA) to provide water utilities with insights that lead to significant energy savings and cost reductions. A distinctive feature of PeakWater is its capability to analyze energy supplier tariffs, allowing water authorities to navigate the competitive energy market effectively while meeting contractual obligations. This positions Peak-Dynamics as a pioneer in the Water-Energy Nexus, offering a unique solution that combines water system management with energy procurement optimization. The company markets its innovative services to water management companies, municipal authorities, and regional entities, delivering enhanced reliability and operational cost savings. With a team of skilled professionals in software development, sales, and water system modeling, Peak-Dynamics is well-equipped for expansion, including a recent establishment of operations in the United States.

CardioGard develops a specially designed arterial cannula for the removal of gaseous material during heart bypass surgeries. The system is composed of a double-lumen cannula in which the primary lumen provides oxygenated blood from the heart-lung machine to the patient and a secondary lumen suctions blood and embolic matter away from the surgical field and back to the cardiopulmonary bypass machine for the filtration.

Eximo Medical Ltd. is an Israeli company specializing in hybrid catheter technology aimed at improving tissue resection in vascular and gastrointestinal endoluminal applications. Founded in 2012 and based in Modi'in-Maccabim-Re'ut, the company has developed the CatHI™, a proprietary single-use hybrid catheter that integrates optical fibers for delivering short laser pulses with a blunt mechanical knife. This innovative design enhances the safety and effectiveness of procedures, particularly in lead extraction and the treatment of peripheral artery disease, by minimizing the risk of vessel perforation. As of October 2019, Eximo Medical operates as a subsidiary of AngioDynamics, Inc.

Otic Pharma is a clinical-stage pharmaceutical company focusing on the development and commercialization of products for disorders of the ear, nose, and throat (ENT). The company has two platform technologies, each of which has the potential to be developed for multiple ENT indications. The company is currently developing a nasally-administered, combination drug product (OP-02) intended to address the underlying cause of otitis media and Eustachian tube dysfunction (OM/ETD), a condition that affects more than 700 million people around the world every year. Otitis media is one of the most common disease seen in pediatric practice and the most frequent reason children consume antibiotics or undergo surgery. The company also has a foam-based drug delivery technology platform (OP-01) that can be used to deliver drugs into the ear, nose, and sinus cavities. The company is currently developing OP-01 as an improved treatment option for acute otitis externa (“swimmers ear”). For more information on the company, please visit www.oticpharma.com

Valire is a software solution company based in HaMerkaz, Israel, specializing in artificial intelligence applications for fraud detection and risk management. Founded in 2009, Valire develops tools that assess fraud risk, validate business processes, and create tailored algorithms to help organizations secure their revenue. By integrating business rules with symbolic machine learning, Valire's software effectively identifies fraudulent behavior while minimizing false positives and ensuring cost-effective implementation. This approach allows businesses to reduce operational risks and enhance performance, ultimately supporting their growth opportunities.

Rocketick Technologies is a software development company founded in 2008 by experts in hardware-assisted acceleration. It specializes in GPU-based simulation acceleration for chip verification, addressing functional verification bottlenecks in the semiconductor industry. Its flagship product, RocketSim, enhances traditional simulators by providing a GPU-based acceleration solution, achieving up to ten times faster simulations for complex chip designs. This innovative approach helps chip manufacturers reduce the overall time to market for new designs, making Rocketick a valuable partner for several semiconductor clients.

QuickLizard is an AI-powered technology provider specializing in dynamic pricing solutions for retailers and direct-to-consumer brands. The company offers a comprehensive platform that enables users to manage their pricing strategies effectively, featuring tools, insights, and analytics aimed at driving business growth and profitability. QuickLizard serves a wide array of retail sectors, including consumer electronics, beauty, home goods, sporting equipment, apparel, pet supplies, groceries, and airlines. Its platform operates in over 40 markets, seamlessly integrating both online and offline sales channels, and generates hundreds of millions of pricing recommendations each month.

CartiHeal is a medical device company based in Kfar Sava, Israel, specializing in cartilage and bone regeneration. Founded in 2009, the company has developed the Agili-C implant, a cell-free and off-the-shelf solution designed to address focal articular cartilage and osteochondral defects. This innovative implant promotes the regeneration of hyaline cartilage and the underlying subchondral bone without the need for cells or growth factors, making it a significant advancement in the treatment of cartilage injuries. Given the limited natural healing capacity of hyaline cartilage, CartiHeal's technology offers a promising option for patients suffering from cartilage damage, which can lead to severe pain and disability if untreated. The Agili-C implant can be inserted using arthroscopic or minimally invasive techniques, facilitating faster rehabilitation and enhanced recovery outcomes for patients.

Cellvine is a company that specializes in developing and marketing advanced coverage and capacity solutions for the wireless telecommunications industry. It offers a wide array of cellular coverage enhancement products, leveraging its proprietary technology to improve cellular signals across various environments. These include in-building spaces, urban areas, rural settings, and challenging subterranean locations such as mines and tunnels. By focusing on innovative wireless communication technologies, Cellvine aims to enhance connectivity and performance for cellular networks.

CardioNova is a biotechnology company focused on developing medical solutions for cardiovascular diseases. The company specializes in creating drugs designed to treat conditions such as atrial fibrillation and dyslipidemia, with the goal of preventing atherosclerosis. By providing innovative therapies, CardioNova aims to enable healthcare providers to achieve clinical objectives efficiently and cost-effectively.

Valtech Cardio Ltd. is a medical device company based in Or Yehuda, Israel, specializing in the development and manufacturing of cardiovascular devices aimed at treating mitral regurgitation and facilitating tricuspid valve repair and replacement. The company focuses on minimally invasive transcatheter heart valve technologies, allowing patients to avoid open-heart surgery. Its key products include the Cardioband System, which performs mitral valve reconstruction via transfemoral direct annuloplasty, and the Cardiovalve system, a transfemoral transseptal replacement option for the mitral valve. Additionally, Valtech offers the Cardinal adjustable annuloplasty ring, which allows surgeons to optimize the ring size during surgery. The company's pipeline includes innovative products such as Cardioband Tricuspid, designed for mitral regurgitation, and V-Chordal, an adjustable implanted chord for repairing valve prolapse. Founded in 2006, Valtech Cardio operates as a subsidiary of Zeppelin Zox Ltd. since January 2017.

Kailight Photonics develops optical modules for the telecommunications industry. It offers tunable optical signal regenerator, an optical component that operates with regenerators, optical switches, add/drop multiplexers, and cross-connects. The company's optical transmission, signal regeneration, and wavelength conversion technology provides optical-networking solutions for systems vendors. It provides its products to long-haul network market segments. The company, formerly known as Chilight Technologies, was founded in 2000 and is headquartered in Rehovot, Israel with an additional office in Dallas, Texas. As of May 15, 2007, Kailight Photonics, Inc. operates as a subsidiary of Optium Corporation.

Neovasc Inc. is a specialty medical device company based in Richmond, Canada, focused on the development, manufacturing, and marketing of products for the cardiovascular marketplace. The company offers innovative solutions, including the Tiara technology for the transcatheter treatment of mitral valve disease and the Neovasc Reducer, designed for the treatment of refractory angina. The Reducer has been commercially available in Europe since 2015, although it is not yet available in the United States. The Tiara device is currently under clinical investigation across multiple regions, including the United States, Canada, and Europe. Neovasc's expertise also extends to pericardial tissue processing and vascular product development, providing comprehensive design and manufacturing solutions to industry partners. Founded in 2000 and originally known as Medical Ventures Corp., Neovasc has positioned itself within a rapidly growing market, focusing on advanced medical technologies to address complex cardiovascular conditions.

TopSpin Medical has developed a groundbreaking technology for high-resolution MRI imaging using an IntraVascular MRI (IVMRI) catheter specifically designed for the coronary arteries. This innovative catheter eliminates the need for expensive and cumbersome external MRI setups by miniaturizing essential MRI components to less than 2 millimeters in size. The advanced technology allows for precise imaging within the coronary arteries, revolutionizing the field of medical imaging and providing a more efficient and cost-effective solution for clinicians and patients alike.

VisionCare Ophthalmic Technologies, Inc. is a specialty medical device company based in Saratoga, California, focused on the research, development, manufacture, and marketing of innovative implantable ophthalmic devices. The company primarily aims to enhance vision and quality of life for individuals suffering from untreatable retinal disorders, particularly end-stage age-related macular degeneration (AMD), which is a leading cause of blindness among older Americans. VisionCare's flagship product is the Implantable Miniature Telescope, the first FDA-approved device designed to improve vision in patients with advanced AMD. This telescope implant is a critical component of the CentraSight treatment program, which guides patients through the processes of diagnosis, surgical evaluation, and postoperative care. Founded in 1997, VisionCare is dedicated to helping patients reconnect with their daily lives and activities through its advanced visual prosthetic technologies.