Quan Capital

Windward Bio is a clinical-stage biopharmaceutical company dedicated to enhancing outcomes for patients with advanced immunological diseases, focusing on severe respiratory conditions. The company is advancing a fully human monoclonal antibody targeting thymic stromal lymphopoietin (TSLP) into phase 2 clinical trials. This antibody, administered subcutaneously, potently binds to the TSLP ligand, extending its half-life and silencing its effector functions. Windward Bio is also developing innovative bispecific programs for other immunological disorders, led by a team of experienced biopharmaceutical executives aiming to address significant unmet medical needs in this field.

Avenzo Therapeutics focuses on developing innovative cancer treatments. It operates a clinical-stage platform dedicated to creating novel therapies for underserved cancers, with a pipeline targeting rare and genomically defined cancers.

Zenas BioPharma is a clinical-stage biopharmaceutical company headquartered in Florida, USA, that specializes in developing immune-based therapies for patients. The company’s lead product candidate, obexelimab, is a bifunctional monoclonal antibody designed to target both CD19 and FcγRIIb, which are found in B cell lineages. This innovative approach aims to inhibit the activity of cells involved in various autoimmune diseases while preserving their presence, thus avoiding depletion. Through its focus on these advanced therapies, Zenas BioPharma seeks to address unmet medical needs in the treatment of autoimmune conditions.

Avenzo Therapeutics focuses on developing innovative cancer treatments. It operates a clinical-stage platform dedicated to creating novel therapies for underserved cancers, with a pipeline targeting rare and genomically defined cancers.

Crescendo Biologics develops innovative antibody therapeutics using its proprietary platforms. The company focuses on generating high-affinity, human VH antibody fragments for oncology and other indications. Its technology is based on a transgenic mouse platform that enables the creation of fully human VHH domain building blocks.

Adcentrx Therapeutics is a biotechnology company focused on protein conjugate therapeutics for cancer and other life-threatening diseases. The company seeks to accelerate breakthroughs in this field by combining the targeting precision of biologics with the potency of small-molecule payloads, enabling next-generation targeted therapies and expanding treatment options for patients.

Alebund Pharmaceuticals is a biopharmaceutical company specializing in the discovery and development of innovative therapies for renal diseases and associated chronic conditions. The company focuses on researching and commercializing treatments for a variety of kidney-related ailments, including chronic kidney disease, dialysis complications, nephropathy, diabetic kidney disease, and autosomal dominant polycystic kidney disease. With a diversified pipeline of drug candidates, Alebund Pharmaceuticals aims to deliver comprehensive, high-quality solutions to patients suffering from renal diseases, addressing both immediate and long-term healthcare needs in this critical area.

Zenas BioPharma is a clinical-stage biopharmaceutical company headquartered in Florida, USA, that specializes in developing immune-based therapies for patients. The company’s lead product candidate, obexelimab, is a bifunctional monoclonal antibody designed to target both CD19 and FcγRIIb, which are found in B cell lineages. This innovative approach aims to inhibit the activity of cells involved in various autoimmune diseases while preserving their presence, thus avoiding depletion. Through its focus on these advanced therapies, Zenas BioPharma seeks to address unmet medical needs in the treatment of autoimmune conditions.

Shanghai Origincell Biological Cryo Equipment Co., Ltd. is a biomedical enterprise established in 2014, headquartered in Shanghai, China. The company specializes in immunological cell collection, separation, and storage services. It manufactures biobanking storage devices, including cryogenic freezers and biobank systems. In addition to its storage solutions, Origincell develops tumor immunotherapy solutions, utilizing advanced technologies such as the 10-phage display library and humanized antibody technology. These innovations support medical facilities in their cancer treatment efforts, positioning Origincell as a key player in the intersection of biobanking and cancer therapy.

OriCell Therapeutics is a biopharmaceutical company that specializes in the development of innovative cellular drugs aimed at addressing unmet clinical needs in tumor immunotherapy. The company focuses on creating therapeutics for a range of cancers, including liver cancer, myeloma, ovarian cancer, gastric cancer, cervical cancer, and non-small cell lung cancer. With a commitment to effective and affordable treatment options, OriCell Therapeutics aims to enhance patient care through the development of clinically valuable therapies, seeking to establish itself as a leader in the field of novel oncological treatments.

Yuanyin Bio is a biotechnology company focuses on the research and application of circular RNA technology in the field of innovative drugs and therapies, builds a robust pipeline of preventive and therapeutic new drugs, and is dedicated to addressing clinically unmet disease needs. They serve in the field of innovative drugs and therapies. It establishes a pipeline of preventive and therapeutic new drugs and is committed to solving clinically unmet disease needs.

Innoforce Pharmaceuticals Co., Ltd is a biopharmaceutical company based in Hangzhou, China, founded in 2018. The company specializes in the development and commercialization of biomedicines and therapies, including cell and gene therapies, medicines, and antibodies. Innoforce operates biologic process development laboratories and offers end-to-end contract development and manufacturing services to support biotech enterprises in their research and development and manufacturing needs. By providing customized product development and operations management, Innoforce enables its clients to effectively bring their biopharmaceutical products to market.

Yuanyin Bio is a biotechnology company focuses on the research and application of circular RNA technology in the field of innovative drugs and therapies, builds a robust pipeline of preventive and therapeutic new drugs, and is dedicated to addressing clinically unmet disease needs. They serve in the field of innovative drugs and therapies. It establishes a pipeline of preventive and therapeutic new drugs and is committed to solving clinically unmet disease needs.

Walking Fish Therapeutics is focused on developing innovative cell-based therapeutics aimed at treating serious diseases, particularly in the fields of oncology and regenerative medicine. The company leverages the unique capabilities of B cells to activate the immune system, thereby creating treatments for cancer and other conditions. Additionally, these B cell factories can function as in vivo protein producers, generating replacement proteins for deficiency diseases and engineered antibodies. By harnessing locally acting proteins, Walking Fish Therapeutics seeks to enhance therapeutic outcomes and provide targeted solutions for patients suffering from various ailments.

Alebund Pharmaceuticals is a biopharmaceutical company specializing in the discovery and development of innovative therapies for renal diseases and associated chronic conditions. The company focuses on researching and commercializing treatments for a variety of kidney-related ailments, including chronic kidney disease, dialysis complications, nephropathy, diabetic kidney disease, and autosomal dominant polycystic kidney disease. With a diversified pipeline of drug candidates, Alebund Pharmaceuticals aims to deliver comprehensive, high-quality solutions to patients suffering from renal diseases, addressing both immediate and long-term healthcare needs in this critical area.

Interius BioTherapeutics is a biopharmaceutical company that develops in vivo cell-specific gene medicines to treat B cell lymphomas. Intravenous in vivo CAR treatment, which treats B cell lymphomas, is the company's flagship program. Its unique engineering provides exceptional target tissue specificity. The business is working on a second initiative to address autoimmune conditions. With the help of Interius, a novel and distinct therapeutic modality for the precise administration of gene therapies may soon be made available to patients in expanded care settings, without the need for preconditioning chemotherapy.

Alebund Pharmaceuticals is a biopharmaceutical company specializing in the discovery and development of innovative therapies for renal diseases and associated chronic conditions. The company focuses on researching and commercializing treatments for a variety of kidney-related ailments, including chronic kidney disease, dialysis complications, nephropathy, diabetic kidney disease, and autosomal dominant polycystic kidney disease. With a diversified pipeline of drug candidates, Alebund Pharmaceuticals aims to deliver comprehensive, high-quality solutions to patients suffering from renal diseases, addressing both immediate and long-term healthcare needs in this critical area.

Zenas BioPharma is a clinical-stage biopharmaceutical company headquartered in Florida, USA, that specializes in developing immune-based therapies for patients. The company’s lead product candidate, obexelimab, is a bifunctional monoclonal antibody designed to target both CD19 and FcγRIIb, which are found in B cell lineages. This innovative approach aims to inhibit the activity of cells involved in various autoimmune diseases while preserving their presence, thus avoiding depletion. Through its focus on these advanced therapies, Zenas BioPharma seeks to address unmet medical needs in the treatment of autoimmune conditions.

Innoforce Pharmaceuticals Co., Ltd is a biopharmaceutical company based in Hangzhou, China, founded in 2018. The company specializes in the development and commercialization of biomedicines and therapies, including cell and gene therapies, medicines, and antibodies. Innoforce operates biologic process development laboratories and offers end-to-end contract development and manufacturing services to support biotech enterprises in their research and development and manufacturing needs. By providing customized product development and operations management, Innoforce enables its clients to effectively bring their biopharmaceutical products to market.

Design Therapeutics, Inc. is a clinical-stage biotechnology company headquartered in Solana Beach, California, focused on developing innovative therapies for serious degenerative disorders caused by nucleotide repeat expansions. The company specializes in a novel class of small-molecule gene-targeted chimera therapeutics known as GeneTACTM molecules, which aim to modify disease progression by addressing the root causes of these conditions. Its lead program targets Friedreich’s ataxia, while additional efforts are directed toward conditions such as Fuchs endothelial corneal dystrophy and other degenerative diseases like Fragile X syndrome and myotonic dystrophy. Since its incorporation in 2017, Design Therapeutics has been dedicated to advancing its therapeutic candidates to potentially transform treatment options for patients suffering from these inherited disorders.

Kira Pharmaceuticals, established in 2017 and headquartered in Suzhou, China, is a biotechnology company focused on developing innovative therapies targeting the complement system to treat immune-mediated diseases.

Kira Pharmaceuticals, established in 2017 and headquartered in Suzhou, China, is a biotechnology company focused on developing innovative therapies targeting the complement system to treat immune-mediated diseases.

Eluminex Biosciences is engaged in the research, development, and commercialization of innovative therapies aimed at addressing unmet medical needs in ocular health. The company focuses on ophthalmology and tissue regeneration, leveraging recombinant human collagen to develop therapeutic solutions. Its pipeline includes treatments designed to slow and mitigate the effects of aging and overuse on vision, ultimately enabling healthcare providers to offer improved care to their patients. Through its commitment to advancing the field of ophthalmology, Eluminex Biosciences seeks to enhance diagnostic and therapeutic options for ocular illnesses.

MEDx is a company specializing in precision medicine solutions aimed at enhancing clinical development. Founded in 2013 and headquartered in Suzhou, Jiangsu, MEDx employs translational science to advance diagnostic technologies related to nucleic acids and proteins. Its comprehensive services include biomarker development, Companion Diagnostics, Point-of-Care development, clinical testing, and the commercialization of medical products. By focusing on individualized treatment, MEDx seeks to improve patient outcomes through its innovative approaches in the healthcare sector.

Citrine Medicine is a rare disease-focused pharmaceutical firm.

Design Therapeutics, Inc. is a clinical-stage biotechnology company headquartered in Solana Beach, California, focused on developing innovative therapies for serious degenerative disorders caused by nucleotide repeat expansions. The company specializes in a novel class of small-molecule gene-targeted chimera therapeutics known as GeneTACTM molecules, which aim to modify disease progression by addressing the root causes of these conditions. Its lead program targets Friedreich’s ataxia, while additional efforts are directed toward conditions such as Fuchs endothelial corneal dystrophy and other degenerative diseases like Fragile X syndrome and myotonic dystrophy. Since its incorporation in 2017, Design Therapeutics has been dedicated to advancing its therapeutic candidates to potentially transform treatment options for patients suffering from these inherited disorders.

Arcellx is a clinical-stage biotechnology company developing immunotherapies and cell therapies for cancer and other serious diseases. It seeks to make cell therapies safer, more effective, and more broadly accessible. Its lead candidate CART-ddBCMA is in a Phase 1 trial for relapsed or refractory multiple myeloma and has FDA Fast Track, Orphan Drug, and Regenerative Medicine Advanced Therapy designations. The company is also advancing ARC-SparX, a dosable and controllable CAR-T platform, into clinical programs ACLX-001 for relapsed or refractory multiple myeloma and ACLX-002 for relapsed or refractory acute myeloid leukemia. Arcellx's pipeline covers multiple myeloma, acute myeloid leukemia, and other cancer indications, with research extending into additional oncology areas and other serious diseases.

NextCure, Inc. is a clinical-stage biopharmaceutical company based in Beltsville, Maryland, that focuses on discovering and developing novel immunomedicines aimed at treating cancer and other immune-related diseases by restoring normal immune function. Its lead product candidate, NC318, is currently undergoing Phase 2 clinical trials for advanced or metastatic solid tumors. Additionally, NextCure is developing NC410, designed to inhibit immune suppression through the modulation of a specific immune receptor. The company is also advancing other product candidates, including LNCB74, an antibody-drug conjugate targeting B7-H4, and is exploring additional immunomodulatory molecules in preclinical stages. NextCure has established collaborations with Yale University for licensing and with Eli Lilly and Company for research and development. Founded in 2015, the company leverages proprietary platforms to identify biologically relevant targets in its pursuit of first-in-class immunotherapy solutions.

Crescendo Biologics develops innovative antibody therapeutics using its proprietary platforms. The company focuses on generating high-affinity, human VH antibody fragments for oncology and other indications. Its technology is based on a transgenic mouse platform that enables the creation of fully human VHH domain building blocks.

Tempest Therapeutics Inc. is a biotechnology company based in South San Francisco, California, focused on developing small molecule therapeutics for cancer treatment. Established in 2011, the company aims to enhance anti-tumor immunity through its innovative drug pipeline, which includes clinical-stage candidates such as TPST-8844, TPST-1120, and TPST-1495. TPST-8844 targets an enzyme that helps tumor cells evade immune responses, while TPST-1120 blocks the PPAR-alpha pathway to stimulate immune effector cells essential for fighting tumors. Additionally, the company's therapeutics address pathways that directly kill tumor cells and activate tumor-specific immunity, positioning Tempest Therapeutics at the forefront of cancer treatment innovation.

Gonbike is a bike-sharing company that addresses urban mobility challenges by offering an innovative biking solution. The company provides an intelligent parking system that assists local operators and users in easily locating the nearest and most suitable parking spots for bikes. Gonbike's bicycles are designed to solve the last mile problem, featuring advanced technology such as an invisible belt smart lock and an LCD screen that displays essential information like speed, battery level, and remaining range. By integrating Internet of Things (IoT) technology, Gonbike enhances the durability and efficiency of its system, ultimately improving overall transportation accessibility for users.

Centrexion Therapeutics Corporation is a late clinical-stage biopharmaceutical company based in Boston, Massachusetts, dedicated to developing novel, non-opioid, and non-addictive therapies for chronic pain management. Founded in 2013, the company focuses on addressing significant unmet medical needs in this area. Its product pipeline includes CNTX-4975, currently in Phase III trials for moderate to severe knee osteoarthritis pain, as well as Phase II trials for Morton’s neuroma and canine osteoarthritis. Additionally, CNTX-0290 is in Phase I trials targeting chronic pain linked to inflammatory and neuropathic conditions. Other candidates include CNTX-6970, also in Phase I for inflammatory pain, and CNTX-2022, a high-concentration topical lidocaine gel in Phase I for various pain types. CNTX-6016 is in pre-clinical stages for chronic neuropathic pain. Centrexion aims to provide patients with safe and effective pain relief options through innovative treatment modalities.

resTORbio, Inc., founded in 2016 and headquartered in Boston, Massachusetts, was a clinical-stage biopharmaceutical company focused on developing medicines to treat aging-related diseases. Its primary approach involved selectively inhibiting the target of rapamycin complex 1 (TORC1), a pathway linked to age-related decline in organ functions. The company's lead drug candidate, RTB101, an oral and potent TORC1 inhibitor, was being evaluated in Phase 1b/2a clinical trials for Parkinson's disease and other neurodegenerative diseases. Prior to its acquisition by Adicet Bio in September 2020, resTORbio collaborated with TrialSpark to investigate RTB-101 as a potential treatment for COVID-19.

ARMO BioSciences is a biotechnology company based in Redwood City, California, focused on developing immune modulatory biologic therapeutics. The company specializes in immuno-oncology, aiming to activate the immune system of cancer patients to recognize and eradicate tumors. Its pipeline includes several product candidates: AM0010, a long-acting form of interleukin 10 (IL-10) that stimulates the immune system; AM0001, an anti-PD-1 monoclonal antibody; AM0003, an anti-LAG-3 checkpoint inhibitor; AM0015, a form of recombinant human interleukin-15 (IL-15); and AM0012, a form of recombinant human interleukin-12 (IL-12). The company was incorporated in 2010 and formerly known as Targenics.

QIAGEN Suzhou is an innovative start-up providing precision medicine solutions.