Rex Health Ventures

410 Medical is a healthcare technology company based in Durham, North Carolina, founded in 2013. The company has developed an innovative rapid infuser device designed to facilitate the swift delivery of fluids to critically ill patients in need of volume resuscitation. This device enhances the speed and efficiency of fluid administration, significantly improving care for patients suffering from life-threatening conditions such as sepsis and shock. By enabling a single healthcare provider to quickly set up and deliver vital fluids, the solution minimizes provider fatigue and allows for simultaneous attention to other patient care needs. It is particularly beneficial in pre-hospital settings and emergency departments, where rapid response is essential and resources may be limited.

G.I. Windows, Inc. is a clinical-stage company based in West Bridgewater, Massachusetts, founded in 2012. The company specializes in manufacturing medical devices utilizing advanced surgical anastomotic technology aimed at treating obesity and type 2 diabetes. G.I. Windows is focused on developing innovative solutions that enable less invasive surgical procedures, thereby creating a new category in healthcare. Its technology is designed to enhance the efficiency of diagnostic and interventional procedures, ultimately improving patient outcomes while reducing overall healthcare costs.

Synaptrix specializes in developing innovative, non-opioid pain management solutions. The company focuses on creating medical devices that employ neuromodulation technology, using electrical or chemical stimulation to alleviate postoperative pain without compromising motor function or touch. This approach aims to provide healthcare professionals with effective, long-lasting alternatives to opioids, promoting rehabilitation and reducing the need for these medications.

Arrivo BioVentures LLC is a biopharmaceutical company based in Morrisville, North Carolina, established in 2015. The company specializes in developing biologics and small molecules aimed at enhancing patient care. Arrivo BioVentures focuses on creating reformulated biopharmaceutical drugs and new chemical entities, employing its expertise in drug development to identify effective regulatory strategies. By coordinating closely with regulatory bodies such as the FDA, the company seeks to streamline the approval process and efficiently implement clinical programs for its products. This approach minimizes potential challenges and accelerates the development timeline, ultimately contributing to improved patient outcomes.

Censinet, Inc. is a cloud-based platform provider focused on managing third-party risk for healthcare organizations. Established in 2017 and headquartered in Winchester, Massachusetts, Censinet's platform facilitates real-time assessments of risks associated with vendors and third-party providers. By connecting healthcare providers with their vendors, the platform streamlines workflows, automates manual processes, and eliminates reliance on inefficient spreadsheets. Censinet delivers continuous insights into the evolving risk profiles of vendors, enabling healthcare companies to effectively address challenges in managing third-party risks while enhancing overall cybersecurity measures.

Vergent Bioscience, Inc. is a company focused on improving cancer surgery outcomes through the development of molecularly-targeted imaging probes. Founded in 2013 and based in Minneapolis, Minnesota, Vergent manufactures a tumor-targeted fluorescent probe, known as VGT-309, which binds to enzymes overexpressed in various cancerous tissues. Upon injection prior to surgery, this probe activates a bright fluorescing dye that illuminates cancerous cells, allowing surgeons to differentiate between malignant and normal tissue with enhanced clarity. By providing a clear visual guide during surgical procedures, Vergent's technology aims to facilitate the complete removal of tumors and reduce the likelihood of residual cancer, thereby addressing a critical need in the surgical oncology field. The company's innovative approach is applicable to multiple cancer types, including lung, breast, ovarian, colorectal, and brain cancers, and is designed to support advanced visualization in various surgical techniques, including open, laparoscopic, and robotic surgeries.

Pryon Inc. is an artificial intelligence company based in Raleigh, North Carolina, founded in 2017. It specializes in enterprise knowledge management through its augmented intelligence platform, which effectively combines human capabilities with machine intelligence. The platform enhances productivity by transforming unstructured data into actionable insights, utilizing advanced techniques such as natural language processing and automated machine learning. By providing context-aware access to knowledge and streamlining workflows, Pryon enables organizations to reduce complexity and operational costs while maximizing the value of their information assets. The company was established by Igor Jablokov, who previously developed AI assistants that contributed to the foundation of Alexa.

BioStable Science & Engineering, Inc. is a cardiovascular device company based in Austin, Texas, that specializes in developing valve repair technologies as alternatives to valve replacement for patients with aortic valve disease. The company offers a range of HAART aortic valve repair technologies, including the HAART 300 aortic annuloplasty device, designed to reduce annular dilatation and restore three-dimensional annular geometry, and the HAART 200 device tailored for bicuspid aortic valve repair. Additionally, BioStable's aortic root restoration system aims to enhance surgical outcomes for patients with aortic insufficiency or aortic root aneurysm. Founded in 2008, BioStable leverages its expertise in product development, regulatory affairs, and clinical validation to minimize time to market for its innovative medical devices, ultimately improving patient care in the cardiovascular field.

Bardy Diagnostics, Inc. is a medical technology company focused on developing and manufacturing innovative cardiac monitoring devices. Its flagship product, the Carnation Ambulatory Monitor (CAM), is a lightweight and discreet cardiac patch that can be worn comfortably for up to seven days, even during exercise or showering. The CAM is specifically designed with a narrow, hourglass shape to enhance comfort, particularly for women. This device captures low amplitude and frequency electrical signals that form the P-wave, allowing for accurate arrhythmia detection and improving clinical decision-making. Bardy Diagnostics also offers BDxCONNECT, a patient management system that facilitates the creation, access, and management of patient CAM reports. Founded in 2013 and headquartered in Seattle, Washington, with additional offices in Houston, Texas, and New Providence, New Jersey, Bardy Diagnostics aims to enhance clinical management and outcomes through advanced ECG detection technologies that promote greater patient compliance and more confident diagnoses by physicians.

Phynd Technologies Inc. is a healthcare technology company based in Dallas, Texas, founded in 2012. It offers a Software-as-a-Service data management platform designed to simplify the management of healthcare provider data for organizations across the United States. The platform, known as Unified Provider Management (UPM), serves as a central hub for managing critical provider information, including billing addresses, communication preferences, licensing details, and exclusionary lists. Additionally, the platform includes tools for provider enrollment, management, outreach, and search, ensuring that healthcare systems can efficiently maintain and utilize provider data across electronic health records, marketing, and claims systems. Phynd Technologies has gained traction in the healthcare industry, with over 350 hospitals and more than 20,000 locations utilizing its solutions to enhance financial outcomes and clinical results while minimizing compliance risks. The company also offers verification services to further support its clients.

Gauss Surgical, Inc. is a medical technology company that specializes in real-time blood monitoring solutions to enhance patient outcomes in surgical and obstetric settings. Founded in 2011 and headquartered in Los Altos, California, Gauss Surgical develops the Triton system, which includes various models suited for different medical needs. Triton assists healthcare professionals in monitoring and estimating blood loss during procedures, allowing for timely intervention in cases of hemorrhage. The system offers objective metrics for blood loss, thereby facilitating better clinical decision-making regarding transfusions. Serving the healthcare sector primarily in the United States, Gauss Surgical's products are designed to integrate seamlessly into existing medical practices, using sophisticated algorithms and HIPAA-compliant technology to deliver accurate monitoring in real time.

Emergo Therapeutics, Inc. is a pharmaceutical company based in Durham, North Carolina, founded in 2016. The company specializes in developing therapeutic drugs aimed at improving immune system function and modulating inflammatory cytokines. Its primary focus is on creating treatment options for flu-like illnesses, specifically through the development of norketotifen for uncomplicated influenza. Emergo Therapeutics seeks to reduce the production of inflammatory cytokines released from mast cells, thereby enabling healthcare providers to manage symptoms and prevent adverse outcomes associated with various infectious diseases and related conditions.

TARGET PharmaSolutions, Inc. specializes in providing real-world data solutions tailored for drug development and commercialization. Founded in 2015 and headquartered in Durham, North Carolina, the company focuses on creating custom datasets and analyses to tackle complex healthcare evidence questions and quality initiatives. It offers a comprehensive health evidence solution that aggregates real-world data from a network of participating sites, in addition to providing bio specimen samples and consulting services. The company's foundation was inspired by the success of HCV-TARGET, a model established in 2011 that demonstrated the efficacy of real-world data in clinical research and regulatory processes. Through its innovative approaches, TARGET PharmaSolutions aims to enhance the drug development process and support evidence-based decision-making in healthcare.

Phononic, Inc. is a semiconductor hardware company based in Durham, North Carolina, founded in 2008. The company specializes in the design, prototyping, and manufacturing of solid-state cooling and heating devices, including thermoelectric chips and heat pumps. Phononic's innovative products replace traditional compressor technology and cooling methods, offering sustainable and precise temperature control without the use of toxic refrigerants. Their applications span various industries, including electronics cooling for optoelectronics and high-performance computing, as well as refrigeration solutions for healthcare, residential, and commercial sectors. By integrating high-performance solid-state heat pumps into a manufacturing-friendly architecture, Phononic aims to deliver smart and energy-efficient solutions that enhance temperature stability while reducing power consumption.

Bluesight operates as a healthcare technology company specializing in supply chain optimization for pharmaceuticals. It offers Medication Intelligence solutions that provide real-time analytics across the entire medication lifecycle, enhancing efficiency, reducing risks, and improving patient safety within hospitals. The core product is an inventory management platform that automates pharmacy kit processing and medication tracking, replacing manual processes to increase operational efficiency and medication visibility.

Arrivo BioVentures LLC is a biopharmaceutical company based in Morrisville, North Carolina, established in 2015. The company specializes in developing biologics and small molecules aimed at enhancing patient care. Arrivo BioVentures focuses on creating reformulated biopharmaceutical drugs and new chemical entities, employing its expertise in drug development to identify effective regulatory strategies. By coordinating closely with regulatory bodies such as the FDA, the company seeks to streamline the approval process and efficiently implement clinical programs for its products. This approach minimizes potential challenges and accelerates the development timeline, ultimately contributing to improved patient outcomes.

Veran Medical Technologies, Inc. is a medical device company specializing in minimally invasive therapeutic devices for interventional oncology. Headquartered in St. Louis, Missouri, the company focuses on developing products that assist physicians in diagnosing diseases and delivering targeted therapies. Its offerings include the SPiNView thoracic navigation system, an electromagnetic device designed for the biopsy of solitary pulmonary nodules, and the ig4 IR System, which aids in performing biopsies and other procedures for the lungs, liver, and kidneys. Additionally, Veran Medical provides various instruments such as the vPad2 tracker device and the SPiNPerc hybrid diagnostic tool. The company's innovative solutions utilize advanced imaging technologies to create dynamic 3D maps of respiratory pathways, enhancing procedural planning and navigation, ultimately helping clinicians to expedite cancer diagnosis and treatment. Founded in 2003, Veran Medical Technologies is committed to improving patient outcomes through precision-guided interventions.

Baebies, Inc., founded in 2014 by Richard West and Vamsee Pamula, specializes in manufacturing screening and pediatric testing equipment for newborn babies. Based in Durham, North Carolina, the company produces SEEKER, a laboratory solution that performs multiple assays simultaneously to measure lysosomal enzyme activity from a single dried blood spot specimen. Additionally, Baebies manufactures FINDER, a near-patient testing device designed for pediatric diagnostics. The company's technology leverages digital microfluidics to maximize diagnostic yield from small sample volumes. SEEKER is FDA authorized and CE marked, while the FINDER platforms are also CE marked, with the FINDER 1.5 SARS-CoV-2 test receiving emergency use authorization from the FDA. Baebies serves hospitals and public health labs, aiming to enhance early disease detection and improve diagnostic capabilities for newborns and patients worldwide.

Bluesight operates as a healthcare technology company specializing in supply chain optimization for pharmaceuticals. It offers Medication Intelligence solutions that provide real-time analytics across the entire medication lifecycle, enhancing efficiency, reducing risks, and improving patient safety within hospitals. The core product is an inventory management platform that automates pharmacy kit processing and medication tracking, replacing manual processes to increase operational efficiency and medication visibility.

Aerial BioPharma is a privately-held biopharmaceutical company based in Morrisville, North Carolina, near Research Triangle Park. Founded in 2011, the company specializes in developing biologics and small molecules targeted at conditions influenced by processes within the central nervous system. Aerial BioPharma's focus includes treatments for narcolepsy and other related conditions, aiming to provide advanced drug therapies for improved healthcare outcomes.

Carta Healthcare, Inc. is a technology company that specializes in developing a software-as-a-service platform aimed at improving hospital patient management. Founded in 2016 and headquartered in San Mateo, California, the company leverages data from existing IT systems to map the patient journey through hospitals. Its platform utilizes machine learning to identify similarities between current patients and past patients, allowing healthcare providers to personalize care based on individual needs. Additionally, it predicts potential bottlenecks, such as recovery bed shortages and cancellations, offering alerts that help hospitals optimize their operations. By combining artificial intelligence with human expertise, Carta Healthcare enhances the efficiency and quality of healthcare data management, ultimately aiming to provide a better experience for patients.