Sequoia Capital Israel

Normunity is a biotechnology company that develops precision immuno‑oncology medicines, termed immune normalizers, designed to restore the body’s natural immune response against cancer. Leveraging a partnership with Dr. Lieping Chen’s laboratory at Yale School of Medicine, the company focuses on newly discovered mechanisms of immune disruption, such as the exclusion of T‑cells from immune‑sensitive tumors and other barriers to normal immune function. Its pipeline includes programs targeting these mechanisms to enable clinicians to treat cancer by reactivating the patient’s own immunity. Normunity operates from offices in Boston, Massachusetts, and West Haven, Connecticut.

Positive Sequence Biology is a biotech company with new gene system-based editing, focused on biotech innovation & breakthrough therapies.

Generation Lab aims to enhance human health by developing the first clinically applicable test that assesses an individual's biological age progression and disease risk. This enables longer, healthier lives.

Wuhan Neurophth Biotechnology Co., Ltd. is a pioneering ophthalmology gene drug research and development company based in Wuhan, China, established in 2008. It focuses on gene therapies for ocular genetic diseases, with a particular emphasis on Leber hereditary optic neuropathy (LHON), a condition caused by genetic mutations. Neurophth has made significant advancements in the field, completing the world's first clinical study of gene therapy for LHON in 2011, which involved nine patients and has since observed their progress over seven years. The company aims to develop effective treatments for various ophthalmic disorders, including degenerative optic nerve injuries and vascular retinopathy, thereby providing physicians with innovative therapeutic options for patients suffering from these conditions.

Lingyi Biology is a gene therapy company that uses a platform to validate the functionality of animal models of rare diseases. It is dedicated to sourcing innovation, with a focus on genetic rare diseases like metabolism, CNS, and ophthalmology. Lingyi Biology has a gene therapy and rare disease discovery, development, and industrialization team, as well as a rare disease animal model preparation and verification platform, to address the pain point of a lack of effective animal models for rare disease research and development.

Bioyond Tech utilizes robotics and artificial intelligence technology to provide a new generation of modular products and automation solutions for the life sciences sector.

MoleculeMind is an AI-driven protein design platform focused on revolutionizing protein discovery, optimization, and design. The company utilizes advanced AI algorithms to enhance the drug development process and has applications across various sectors, including industrial production, agriculture, material design, and environmental improvement. MoleculeMind offers an integrated biological computing platform that enables the prediction and design of peptides, antibodies, enzymes, and small proteins, facilitating industrial-scale protein optimization and design for diverse research and application needs.

PhaBuilder is a technology-driven company established in February 2021 by Professor Guoqiang Chen, specializing in synthetic biology with a focus on the engineering application of halophilic microbes. The company employs advanced techniques in Next Generation Industrial Biotechnology to create high-value products such as biodegradable polyhydroxyalkanoates (PHA), ectoine, and cadaverine, targeting multiple sectors, including materials and pharmaceuticals. PhaBuilder is currently constructing two PHA production facilities in China and aims to establish 3-5 large-scale production sites within five years. The company utilizes an interdisciplinary approach that combines biology, engineering, and information technology to transform genetic programs, thereby offering sustainable solutions across diverse fields. With significant backing from notable investors, PhaBuilder is dedicated to integrating synthetic biotechnology into everyday life and advancing intelligent biological manufacturing, with the overarching goal of fostering a greener future through microbial innovation.

Cataya Bio (Shanghai) Co., Ltd. is a biotechnology company focused on developing synthetic biological products for various industries. Utilizing an advanced engineering biology platform, Cataya Bio engineers microbes and implements clean fermentation processes to produce high-purity products efficiently and sustainably. The company aims to facilitate the transition from petroleum-based materials to natural and sustainable raw materials, addressing critical global challenges such as environmental preservation, carbon emissions, and climate change. Through its innovative approach, Cataya Bio provides clients with effective solutions for sourcing raw materials that align with contemporary sustainability goals.

Biosysen operates as a synthetic biology company specializing in species design. It employs software engineering principles to enhance biological productivity through self-replicating, scalable systems. The company's core offerings include artificial species libraries and associated pipelines tailored to specific industrial needs, with a focus on food, daily chemicals, and protein drug research and development.

Bioforany is a biocatalyst manufacturer focused on the development and sale of innovative biocatalysts for various industries. The company produces a range of products, including chiral alcohols, chiral amines, chiral hydroxy acids, amino acids, chiral epoxides, lipases, oxidoreductases, and epoxidases. Utilizing advanced green biomanufacturing technology, Bioforany offers low-carbon solutions that cater to multiple sectors, such as pharmaceutical intermediates, traditional Chinese medicine decoction components, functional food, animal nutrition, daily chemical care, plant protection, and renewable materials.

MoleculeMind is an AI-driven protein design platform focused on revolutionizing protein discovery, optimization, and design. The company utilizes advanced AI algorithms to enhance the drug development process and has applications across various sectors, including industrial production, agriculture, material design, and environmental improvement. MoleculeMind offers an integrated biological computing platform that enables the prediction and design of peptides, antibodies, enzymes, and small proteins, facilitating industrial-scale protein optimization and design for diverse research and application needs.

Grit Science is a biotechnology company specializing in gene therapeutics, focusing on the research and development of liver-related genetic treatments. The firm is dedicated to creating innovative medical products that address clinical needs and enhance human health. Through its commitment to advancing biopharmaceutical technology, Grit Science aims to provide effective solutions in the field of genetic medicine.

Lingyi Biology is a gene therapy company that uses a platform to validate the functionality of animal models of rare diseases. It is dedicated to sourcing innovation, with a focus on genetic rare diseases like metabolism, CNS, and ophthalmology. Lingyi Biology has a gene therapy and rare disease discovery, development, and industrialization team, as well as a rare disease animal model preparation and verification platform, to address the pain point of a lack of effective animal models for rare disease research and development.

HemaCell is a biotechnology company specializing in cell therapy, specifically focused on regenerating hematopoietic lineages, which include blood and immune cells, through advanced in vitro techniques. Leveraging innovative stem cell reprogramming, editing, and differentiation technologies, HemaCell aims to address the critical shortage of platelets necessary for treating various diseases such as cancer, liver disease, critical illness, and hematological disorders. The company employs a unique platform that utilizes platelets as drug delivery carriers, facilitating the rapid establishment of induced pluripotent stem cells (iPSCs) and gene targeting technologies. In addition to platelet production, HemaCell is dedicated to developing novel therapeutic solutions for diseases associated with platelet abnormalities, thereby offering effective treatment options and addressing significant medical needs.

PhaBuilder is a technology-driven company established in February 2021 by Professor Guoqiang Chen, specializing in synthetic biology with a focus on the engineering application of halophilic microbes. The company employs advanced techniques in Next Generation Industrial Biotechnology to create high-value products such as biodegradable polyhydroxyalkanoates (PHA), ectoine, and cadaverine, targeting multiple sectors, including materials and pharmaceuticals. PhaBuilder is currently constructing two PHA production facilities in China and aims to establish 3-5 large-scale production sites within five years. The company utilizes an interdisciplinary approach that combines biology, engineering, and information technology to transform genetic programs, thereby offering sustainable solutions across diverse fields. With significant backing from notable investors, PhaBuilder is dedicated to integrating synthetic biotechnology into everyday life and advancing intelligent biological manufacturing, with the overarching goal of fostering a greener future through microbial innovation.

Virtue Diagnostics (Suzhou) Co., Ltd. is an in vitro diagnostic (IVD) company based in Suzhou, China, with a research and development office in Singapore. Founded in 2019, the company specializes in developing advanced diagnostic platforms for the detection of infectious diseases, cancer, and chronic diseases. Its technology offerings include clinical mass spectrometry, multiplex immunohistochemistry for pathology-based cancer detection, and a molecular and immunoassay platform. Virtue Diagnostics aims to enhance diagnostic capabilities and improve patient outcomes through its innovative solutions.

Atom Bioscience is a clinical-stage biotechnology company focused on developing innovative treatments for inflammatory and metabolic diseases. Its pipeline includes therapies for chronic gout and non-alcoholic steatohepatitis (NASH).

ABclonal Inc. is a life science research and diagnostic reagents provider based in Woburn, Massachusetts, founded in 2016. The company specializes in offering a variety of biological research agents and services, including next generation sequencing library preparation kits, molecular biology products, catalog antibodies, catalog proteins, ELISA kits, and western blot tools and reagents. In addition to its extensive product range, ABclonal provides customized services related to peptides, antibodies, and proteins. The company distributes its products through a network of distributors across Europe, Asia, North America, and Oceania, aiming to enhance the quality of life science research with its high-quality offerings.

Shanghai Duoning Biotechnology Co., Ltd. specializes in the development of serum-free, personalized, and chemically defined cell culture media for the biopharmaceutical industry. Founded in 2005 and based in Shanghai, the company offers a range of products, including basic media, feed media, and cell therapy media. Duoning Biotech is dedicated to providing tailored media development, cell culture process optimization, and commissioned formula production services, utilizing its expertise in animal cell culture concepts. The company supports the research, development, and commercialization of biologics products by delivering comprehensive solutions that encompass technical support and customized services tailored to the needs of pharmaceutical and scientific research institutions.

Wuhan Neurophth Biotechnology Co., Ltd. is a pioneering ophthalmology gene drug research and development company based in Wuhan, China, established in 2008. It focuses on gene therapies for ocular genetic diseases, with a particular emphasis on Leber hereditary optic neuropathy (LHON), a condition caused by genetic mutations. Neurophth has made significant advancements in the field, completing the world's first clinical study of gene therapy for LHON in 2011, which involved nine patients and has since observed their progress over seven years. The company aims to develop effective treatments for various ophthalmic disorders, including degenerative optic nerve injuries and vascular retinopathy, thereby providing physicians with innovative therapeutic options for patients suffering from these conditions.

KingstronBio specializes in the development and manufacturing of advanced heart valve products for cardiac surgeries. The company focuses on creating a comprehensive range of biological heart valves and annuloplasty rings that are designed to be minimally invasive. Utilizing cutting-edge technologies, including anti-calcification and leaflet thinning methods, KingstronBio aims to provide innovative solutions that enhance patient outcomes and improve the overall effectiveness of cardiac procedures.

Positive Sequence Biology is a biotech company with new gene system-based editing, focused on biotech innovation & breakthrough therapies.

Structure Therapeutics is a clinical-stage biopharmaceutical company focused on discovering and developing oral small-molecule medicines for chronic diseases with high unmet medical needs. Its platform combines structure-based drug design, computational chemistry, and data integration to create orally available therapies that overcome limitations of biologics and peptide drugs. The company concentrates on targeting G-protein coupled receptors and other mechanisms, leveraging structural insights to identify differentiated, efficacious, and safe treatments. Its programs address cardiovascular, metabolic, and pulmonary conditions, with a focus on delivering convenient, effective medicines that can offer broad patient impact and commercial potential. Structure Therapeutics conducts its research and development activities across its pipeline within a single organization and seeks to advance clinical candidates through development.

PhaBuilder is a technology-driven company established in February 2021 by Professor Guoqiang Chen, specializing in synthetic biology with a focus on the engineering application of halophilic microbes. The company employs advanced techniques in Next Generation Industrial Biotechnology to create high-value products such as biodegradable polyhydroxyalkanoates (PHA), ectoine, and cadaverine, targeting multiple sectors, including materials and pharmaceuticals. PhaBuilder is currently constructing two PHA production facilities in China and aims to establish 3-5 large-scale production sites within five years. The company utilizes an interdisciplinary approach that combines biology, engineering, and information technology to transform genetic programs, thereby offering sustainable solutions across diverse fields. With significant backing from notable investors, PhaBuilder is dedicated to integrating synthetic biotechnology into everyday life and advancing intelligent biological manufacturing, with the overarching goal of fostering a greener future through microbial innovation.

Westlake Therapeutics is a biopharmaceutical company based in Hangzhou, China, founded in 2019. The company specializes in developing innovative cell therapies aimed at treating a range of human diseases, including cancer, rare disorders, and immunological and metabolic conditions. Central to its approach is the REDx platform, which enables the engineering of red blood cells and utilizes genetic modifications of hematopoietic stem and progenitor cells sourced from peripheral blood, bone marrow, or cord blood. This technology facilitates the creation of personalized treatment solutions, enhancing the potential for effective therapies tailored to individual patient needs.

neoX Biotech is a Beijing-based biotechnology company founded in 2018 that specializes in the development of antigen-based cancer vaccines. By integrating artificial intelligence with biophysics, neoX Biotech focuses on the discovery and development of macromolecular and multispecific drugs, primarily in the field of immuno-oncology. The company has established a platform for early therapeutic discovery, which includes neoantigen prediction and T cell receptor screening, as well as the characterization of protein-protein interactions. This innovative approach aims to provide effective treatments for cancer patients by advancing drug research and development.

Biosysen operates as a synthetic biology company specializing in species design. It employs software engineering principles to enhance biological productivity through self-replicating, scalable systems. The company's core offerings include artificial species libraries and associated pipelines tailored to specific industrial needs, with a focus on food, daily chemicals, and protein drug research and development.

MoonBiotech is a biotechnology company focused on the commercialization of microbial resources.

HiFiBiO is a biotherapeutics company focused on harnessing the human immune system to address diseases, particularly cancer and autoimmune disorders. Founded in 2013 and based in Paris, the company specializes in proprietary single-cell technologies that facilitate drug and biomarker discovery and development. HiFiBiO's platform combines extensive biological knowledge with advanced single-cell profiling techniques, allowing for the rapid identification and advancement of antibody drugs. Through partnerships with both industry and academic institutions, HiFiBiO aims to promote open innovation and enhance patient outcomes by unlocking the therapeutic potential of the immune system.

Stemirna Therapeutics is a RNA technology based drug development company designed to maximize the potential of RNA science. The company currently has more than a dozen of independently-developed mRNA drug projects, focusing on the fields of mRNA-based personalized cancer vaccines, mRNA vaccines for infectious disease, protein defects diseases, and genetic diseases, providing cure and solutions for cancer and infectious diseases, better serving patients.

Analytical Biosciences is a developer of single-cell genomics focused on creating precise maps of human diseases. The company collaborates with medical research institutions, hospitals, and pharmaceutical firms to leverage single-cell genomics and bioinformatics for improving disease diagnosis and treatment. By conducting large-scale systematic mapping of diseases at the single-cell level, Analytical Biosciences engages in extensive data mining to support its partners in discovering new therapeutic targets and developing innovative treatment strategies. Utilizing high-resolution databases and advanced data analytics, the company aims to unlock disease mechanisms and facilitate the identification and validation of novel cellular targets and biomarkers. This approach positions Analytical Biosciences at the forefront of advancing next-generation therapeutics and diagnostics.

Phanes Therapeutics is a biotechnology company specializing in drug discovery for immuno-oncology and eye diseases. Established in 2016, the company focuses on developing monoclonal antibodies for solid tumors and conditions like age-related macular degeneration, diabetic macular edema, and diabetic retinopathy. Additionally, they work on bispecific antibodies targeting small cell lung cancer.

EdiGene Inc. is a biotechnology company specializing in the development of genome editing technologies for therapeutic applications in cancer and various genetic diseases. Founded in 2015 and headquartered in Beijing, China, with additional offices in Guangzhou and Cambridge, Massachusetts, EdiGene focuses on both ex vivo and in vivo gene-editing therapies. The company has established proprietary platforms for editing hematopoietic stem cells and T cells, as well as an RNA base editing approach for in vivo applications. EdiGene's innovative methods enable targeted modifications of genetic information in human cells and facilitate high-throughput drug discovery through advanced screening techniques. By translating these technologies into novel therapeutics, EdiGene aims to improve the safety and efficacy of gene therapy, ultimately benefiting patients, the pharmaceutical industry, and the scientific research community.

Benchling, Inc. delivers a cloud-based informatics platform for life sciences research and development. The platform unifies experiment design, data capture, and collaboration in a single interface, enabling scientists to design, record, and share experiments. It consists of an integrated lab notebook, a biological registration system to track inventory such as plasmids, antibodies, and cell lines, and a molecular biology design and analysis suite that supports end-to-end R&D workflows. Additional modules include Benchling Insights for querying and visualizing structured data and collaboration around it, and Bioregistry for biological entity registration and strain management. Benchling serves researchers in biotechnology and pharmaceutical companies as well as academic and government labs, including research and development managers and principal investigators who need centralized data management and streamlined collaboration. The platform is applied across antibodies, cell therapy, gene therapy, proteins and peptides, vaccines, and industrial biotechnology. Founded in 2012 and based in San Francisco, Benchling enables scientists to design DNA, manage workflows, and accelerate decision-making throughout the R&D lifecycle.

OnCusp Therapeutics is a biopharmaceutical company dedicated to accelerating oncology medication innovation globally. It focuses on translating preclinical drug candidates into clinical proof-of-concept stage and advancing them for rapid global early clinical development.

Qihan Biotech is a biomedical company specializing in genetic technology with a focus on addressing the global shortage of organ donors. The company aims to produce safe and effective cells, tissues, and organs for human transplantation using advanced gene editing techniques. By applying these technologies to xenogenic organ transplantation, Qihan Biotech seeks to create organs that can be transplanted into humans, thereby reducing the need for traditional organ transplants and saving lives.

ABclonal Inc. is a life science research and diagnostic reagents provider based in Woburn, Massachusetts, founded in 2016. The company specializes in offering a variety of biological research agents and services, including next generation sequencing library preparation kits, molecular biology products, catalog antibodies, catalog proteins, ELISA kits, and western blot tools and reagents. In addition to its extensive product range, ABclonal provides customized services related to peptides, antibodies, and proteins. The company distributes its products through a network of distributors across Europe, Asia, North America, and Oceania, aiming to enhance the quality of life science research with its high-quality offerings.

Wuhan Neurophth Biotechnology Co., Ltd. is a pioneering ophthalmology gene drug research and development company based in Wuhan, China, established in 2008. It focuses on gene therapies for ocular genetic diseases, with a particular emphasis on Leber hereditary optic neuropathy (LHON), a condition caused by genetic mutations. Neurophth has made significant advancements in the field, completing the world's first clinical study of gene therapy for LHON in 2011, which involved nine patients and has since observed their progress over seven years. The company aims to develop effective treatments for various ophthalmic disorders, including degenerative optic nerve injuries and vascular retinopathy, thereby providing physicians with innovative therapeutic options for patients suffering from these conditions.

neoX Biotech is a Beijing-based biotechnology company founded in 2018 that specializes in the development of antigen-based cancer vaccines. By integrating artificial intelligence with biophysics, neoX Biotech focuses on the discovery and development of macromolecular and multispecific drugs, primarily in the field of immuno-oncology. The company has established a platform for early therapeutic discovery, which includes neoantigen prediction and T cell receptor screening, as well as the characterization of protein-protein interactions. This innovative approach aims to provide effective treatments for cancer patients by advancing drug research and development.

Jifan Biotechnology is a biotechnology firm that provides molecular biology reagents, diagnostic raw materials, and kits for research.

Visen Pharmaceuticals is an innovative biopharmaceutical company focused on developing and providing advanced treatments for endocrine diseases in China. With a patient-centric approach, Visen aims to deliver first-in-class or best-in-class products, covering both common and rare endocrine conditions in adults and children. The company leverages cutting-edge technologies and global resources, with established offices in Shanghai, Beijing, Hong Kong, and Taipei, along with a Greater China R&D and manufacturing site in Suzhou.

Positive Sequence Biology is a biotech company with new gene system-based editing, focused on biotech innovation & breakthrough therapies.

SciNeuro Pharmaceuticals is a biotechnology company based in Shanghai, China, focused on developing innovative medicines for patients with central nervous system (CNS) diseases. The company is committed to transforming the treatment landscape for these conditions through a robust product pipeline that emphasizes internal innovation and global collaboration. SciNeuro's drug development is guided by breakthrough scientific evidence, including insights from human genetics and pharmacology, targeting the underlying mechanisms of CNS diseases. By addressing these pathological mechanisms, SciNeuro aims to provide transformative therapies that not only aim to cure these diseases but also enhance the quality of life for patients.

D3 Bio, established in 2020, is a biotechnology company headquartered in China. It specializes in the development and registration of innovative medicines, primarily focusing on oncology and immunology. The company's approach involves analyzing clinical and market data to identify gaps in current treatments, employing unique drug development methodologies to target new disease areas and routes, and ultimately providing patients with alternative therapeutic options.

EdiGene Inc. is a biotechnology company specializing in the development of genome editing technologies for therapeutic applications in cancer and various genetic diseases. Founded in 2015 and headquartered in Beijing, China, with additional offices in Guangzhou and Cambridge, Massachusetts, EdiGene focuses on both ex vivo and in vivo gene-editing therapies. The company has established proprietary platforms for editing hematopoietic stem cells and T cells, as well as an RNA base editing approach for in vivo applications. EdiGene's innovative methods enable targeted modifications of genetic information in human cells and facilitate high-throughput drug discovery through advanced screening techniques. By translating these technologies into novel therapeutics, EdiGene aims to improve the safety and efficacy of gene therapy, ultimately benefiting patients, the pharmaceutical industry, and the scientific research community.

Dizal Pharmaceutical is a research-driven biotechnology company that specializes in the discovery, development, and commercialization of innovative medicines. The company focuses on creating first-in-class and best-in-class therapeutic solutions, emphasizing the development of groundbreaking drugs. With a commitment to advancing healthcare, Dizal engages in extensive research and development activities, alongside production and sales of its pharmaceutical products. Through its efforts, Dizal aims to contribute significantly to the pharmaceutical industry by delivering effective treatments that address unmet medical needs.

LP Pharmaceuticals (Xiamen) Co., Ltd., located in Xiamen Biomedical Industry Base which formulates and manufactures pharmaceuticals with enhanced delivery properties. The company was founded in 2012 by a group of scientists and business professionals with extensive experience in the US and Chinese pharmaceutical industry. Proprietary delivery platforms include mucosal and oral controlled release. Therapeutic areas currently concern central nervous system, digestive system, cardiovascular, cancer and AIDS.

neoX Biotech is a Beijing-based biotechnology company founded in 2018 that specializes in the development of antigen-based cancer vaccines. By integrating artificial intelligence with biophysics, neoX Biotech focuses on the discovery and development of macromolecular and multispecific drugs, primarily in the field of immuno-oncology. The company has established a platform for early therapeutic discovery, which includes neoantigen prediction and T cell receptor screening, as well as the characterization of protein-protein interactions. This innovative approach aims to provide effective treatments for cancer patients by advancing drug research and development.

Simcha Therapeutics is a biopharmaceutical company focused on developing engineered cytokine immunotherapy for cancer treatment. Founded in 2018 and headquartered in New Haven, Connecticut, the company utilizes directed evolution to create novel cytokines that enhance the immune system's ability to combat diseases. Its lead program, ST-067, is a designer IL-18 cytokine that has demonstrated significant antitumor effects in animal models, both as a standalone treatment and in combination with anti-PD-1 checkpoint inhibitors. This innovative approach aims to provide patients with more effective immunotherapies, thereby improving their ability to fight cancer.

Atom Bioscience is a clinical-stage biotechnology company focused on developing innovative treatments for inflammatory and metabolic diseases. Its pipeline includes therapies for chronic gout and non-alcoholic steatohepatitis (NASH).

Wuhan Neurophth Biotechnology Co., Ltd. is a pioneering ophthalmology gene drug research and development company based in Wuhan, China, established in 2008. It focuses on gene therapies for ocular genetic diseases, with a particular emphasis on Leber hereditary optic neuropathy (LHON), a condition caused by genetic mutations. Neurophth has made significant advancements in the field, completing the world's first clinical study of gene therapy for LHON in 2011, which involved nine patients and has since observed their progress over seven years. The company aims to develop effective treatments for various ophthalmic disorders, including degenerative optic nerve injuries and vascular retinopathy, thereby providing physicians with innovative therapeutic options for patients suffering from these conditions.

CERo Therapeutics is a biotechnology company focused on cellular immunotherapy and next-generation engineered T cell therapeutics for cancer. It develops platforms that integrate innate and adaptive immune programs to enhance anti-tumor activity and engage the body's full immune repertoire. The company was incorporated in 2016 and is headquartered in San Francisco, California. Its lead product, CER-1236, is an autologous T-cell therapy targeting a novel tumor antigen, TIM-4 ligand.

Adagene is a clinical-stage biotechnology company focused on developing immuno-oncology antibodies targeting novel epitopes. It employs its proprietary Smart Antibody Technology to enhance success rates, expedite time to market, and reduce development costs for therapeutic antibodies.

RootPath Genomics, Inc. is a biotechnology company founded in 2017 and headquartered in Cambridge, Massachusetts. The company specializes in developing a next-generation T-cell therapy platform that integrates precision medicine with cancer immunotherapy. By focusing on the analysis and manipulation of individual immune cells, RootPath aims to enhance immune responses and improve cell therapy efficacy. Its innovative technologies allow for precise monitoring and modulation of the immune system, which is intended to revolutionize the diagnosis and treatment of cancer.

BGI is a biotechnology company specializing in genomics. It provides genome sequencing and genetic testing services to research institutions and healthcare professionals worldwide. The company's offerings include bioinformatics, multi-omics solutions, and related tools, catering to a diverse range of clients such as pharmaceutical companies and academic institutions. BGI's work has contributed significantly to genetic and genomic research, with notable collaborations including Eli Lilly and Company, Merck, Pfizer Inc., and the Bill & Melinda Gates Foundation.

Qihan Biotech is a biomedical company specializing in genetic technology with a focus on addressing the global shortage of organ donors. The company aims to produce safe and effective cells, tissues, and organs for human transplantation using advanced gene editing techniques. By applying these technologies to xenogenic organ transplantation, Qihan Biotech seeks to create organs that can be transplanted into humans, thereby reducing the need for traditional organ transplants and saving lives.

HiFiBiO is a biotherapeutics company focused on harnessing the human immune system to address diseases, particularly cancer and autoimmune disorders. Founded in 2013 and based in Paris, the company specializes in proprietary single-cell technologies that facilitate drug and biomarker discovery and development. HiFiBiO's platform combines extensive biological knowledge with advanced single-cell profiling techniques, allowing for the rapid identification and advancement of antibody drugs. Through partnerships with both industry and academic institutions, HiFiBiO aims to promote open innovation and enhance patient outcomes by unlocking the therapeutic potential of the immune system.

Cullgen Inc. is a clinical-stage biopharmaceutical company developing small molecule therapeutics based on its uSMITE platform, which enables targeted protein degradation by using novel E3 ligands to selectively degrade disease-causing proteins. The approach aims to address cancers, inflammatory and autoimmune diseases, and other conditions lacking effective therapies. Founded in 2018 and based in San Diego, Cullgen's pipeline includes degrader programs such as TRK and GSPT1, as well as other candidates like DAC.

Burning Rock Biotech is a cancer diagnostics company that leverages next-generation sequencing and bioinformatics to guide personalized cancer treatment. It develops and provides a portfolio of tissue- and blood-based, NGS-driven therapy selection tests, including OncoScreen Plus, LungPlasma, ColonCore and HRDCore, and evaluates biomarkers such as microsatellite instability, tumor mutation burden, and NTRK fusions across multiple cancer types, including lung, gastrointestinal, prostate, breast, hematologic, thyroid, colorectal, ovarian, pancreatic, and bladder cancers. The company supports clinical and research use through one-stop services spanning genetic testing and companion diagnostic development, operating through central laboratory and in-hospital models. It collaborates with major pharmaceutical companies on clinical trials and research to advance targeted therapies and diagnostics. Founded in 2014, it is headquartered in Guangzhou, with a Guangzhou laboratory and an R&D center in Shanghai, reflecting its focus on expanding access to precision oncology in China.

BrightGene Bio-Medical Technology Company is a biopharmaceutical firm based in Suzhou, China, specializing in the research, development, manufacturing, and commercialization of innovative medicines and high-quality generic active pharmaceutical ingredients (APIs) and finished dosage forms (FDFs). The company has a diverse product pipeline that includes immuno-oncological agents, GLP-1 receptor agonists for type 2 diabetes, and antibody-drug conjugates aimed at treating solid tumors and brain cancers. Additionally, BrightGene develops a variety of treatments such as Eribulin, Trabectedin, and various macromolecules and cytotoxic payloads. Its product offerings span multiple therapeutic areas, including oncology, cardiology, infectious diseases, and immunology. Founded in 2001, BrightGene has positioned itself as a leader in small molecules and nucleotide drugs, focusing on advancing therapeutics across all stages of development.

RootPath Genomics, Inc. is a biotechnology company founded in 2017 and headquartered in Cambridge, Massachusetts. The company specializes in developing a next-generation T-cell therapy platform that integrates precision medicine with cancer immunotherapy. By focusing on the analysis and manipulation of individual immune cells, RootPath aims to enhance immune responses and improve cell therapy efficacy. Its innovative technologies allow for precise monitoring and modulation of the immune system, which is intended to revolutionize the diagnosis and treatment of cancer.

Qihan Biotech is a biomedical company specializing in genetic technology with a focus on addressing the global shortage of organ donors. The company aims to produce safe and effective cells, tissues, and organs for human transplantation using advanced gene editing techniques. By applying these technologies to xenogenic organ transplantation, Qihan Biotech seeks to create organs that can be transplanted into humans, thereby reducing the need for traditional organ transplants and saving lives.

Farcast Biosciences, established in 2019, is a clinical diagnostic company based in Boston, Massachusetts, with operations in Bangalore, India. The company specializes in developing and utilizing a proprietary Human Tumor Micro Dynamics (HTMD) platform. This platform preserves the natural state of human tumors through the culture of fresh, unmodified tumor fragments, creating a human tumor microenvironment. Farcast's technology enables oncologists to evaluate individual tumors and predict patient response to treatments before initiating therapy. Additionally, it serves drug developers and researchers by providing accurate and precise models for testing and analysis, facilitating the development of personalized cancer therapies.

Eden Biologics is a biopharmaceutical company that focuses on developing biosimilars and providing contract development and manufacturing services to clients and partners in the biopharmaceutical industry. The company specializes in producing complex dosage forms, including oral solids, liquids, semi-solids for both prescription and over-the-counter products, as well as macromolecule biologics. Eden Biologics offers expertise in manufacturing biologics from cell line development through commercial production, with a global and regional regulatory affairs knowledge base to ensure affordability and accessibility of biopharmaceuticals worldwide.

HiFiBiO is a biotherapeutics company focused on harnessing the human immune system to address diseases, particularly cancer and autoimmune disorders. Founded in 2013 and based in Paris, the company specializes in proprietary single-cell technologies that facilitate drug and biomarker discovery and development. HiFiBiO's platform combines extensive biological knowledge with advanced single-cell profiling techniques, allowing for the rapid identification and advancement of antibody drugs. Through partnerships with both industry and academic institutions, HiFiBiO aims to promote open innovation and enhance patient outcomes by unlocking the therapeutic potential of the immune system.

MabSpace Biosciences is a biotechnology company established in 2013, specializing in the discovery and development of innovative antibody-based therapeutics aimed at treating cancer and fibrotic diseases affecting the lungs, kidneys, and liver. Located in Biobay Suzhou, a notable biotech incubator in China, the company employs its proprietary immune tolerance breaking technology (IMBT) to generate lead antibodies with diverse epitopes. This technology allows MabSpace to develop therapeutics that target various components of the tumor microenvironment, enhancing treatment efficacy. The company has established multiple partnerships for antibody discovery and co-development, and it has advanced its lead antibody program, which includes a potentially best-in-class anti-PD-L1 antibody known for its unique pH-dependent binding and recycling properties. Additionally, MabSpace has developed a panel of second-generation immuno-oncology antibodies that facilitate the exploration of combination therapeutic interventions alongside its PD-L1 antibody.

CStone Pharmaceuticals, founded in 2015, focuses on developing and commercializing innovative immunotherapy and precision treatment drugs for cancer patients worldwide. Its pipeline comprises over a dozen candidates targeting various indications, with immuno-oncology at its core.

Refuge Biotechnologies, Inc. is a biotechnology company focused on developing innovative cancer immunotherapies. Founded in 2015 and based in Menlo Park, California, the company utilizes advanced gene-editing technology, specifically CRISPR-dCas, to create cell therapies that are capable of sensing their environment and conditionally regulating multiple genes at once. This approach enables Refuge to enhance the potency and specificity of its treatments, allowing for more effective targeting of cancer cells compared to traditional therapies that focus on a single target. Through its research and development efforts, Refuge aims to unlock the full potential of cell therapies in the fight against cancer.

Adagene is a clinical-stage biotechnology company focused on developing immuno-oncology antibodies targeting novel epitopes. It employs its proprietary Smart Antibody Technology to enhance success rates, expedite time to market, and reduce development costs for therapeutic antibodies.

Founded in 2015, Oxford Science Enterprises is a venture firm that partners with the University of Oxford to build science-based businesses. It invests primarily in life sciences, AI and software, healthcare, and deep tech sectors, aiming to create companies capable of addressing global challenges such as infectious diseases and nuclear fusion.

Burning Rock Biotech is a cancer diagnostics company that leverages next-generation sequencing and bioinformatics to guide personalized cancer treatment. It develops and provides a portfolio of tissue- and blood-based, NGS-driven therapy selection tests, including OncoScreen Plus, LungPlasma, ColonCore and HRDCore, and evaluates biomarkers such as microsatellite instability, tumor mutation burden, and NTRK fusions across multiple cancer types, including lung, gastrointestinal, prostate, breast, hematologic, thyroid, colorectal, ovarian, pancreatic, and bladder cancers. The company supports clinical and research use through one-stop services spanning genetic testing and companion diagnostic development, operating through central laboratory and in-hospital models. It collaborates with major pharmaceutical companies on clinical trials and research to advance targeted therapies and diagnostics. Founded in 2014, it is headquartered in Guangzhou, with a Guangzhou laboratory and an R&D center in Shanghai, reflecting its focus on expanding access to precision oncology in China.

Farcast Biosciences, established in 2019, is a clinical diagnostic company based in Boston, Massachusetts, with operations in Bangalore, India. The company specializes in developing and utilizing a proprietary Human Tumor Micro Dynamics (HTMD) platform. This platform preserves the natural state of human tumors through the culture of fresh, unmodified tumor fragments, creating a human tumor microenvironment. Farcast's technology enables oncologists to evaluate individual tumors and predict patient response to treatments before initiating therapy. Additionally, it serves drug developers and researchers by providing accurate and precise models for testing and analysis, facilitating the development of personalized cancer therapies.

Zai Lab is a biopharmaceutical company dedicated to discovering and developing transformative medicines for cancer, autoimmune, and infectious diseases. Founded in Shanghai in 2014, the company focuses on bringing innovative therapies to patients worldwide. Zai Lab's pipeline includes proprietary drug candidates such as Niraparib, Optune, Ripretinib, and Margetuximab, among others. The company collaborates with global biopharma leaders to expand its pipeline and foster innovation in China.

Founded in 2001, Celon Laboratories is a Hyderabad-based pharmaceutical company specializing in the development, manufacturing, and marketing of niche therapy products. Its portfolio includes oncology and critical care products, available in various dosage forms, serving markets across Asia Pacific, Africa, Latin America, CIS countries, and Eastern Europe.

Burning Rock Biotech is a cancer diagnostics company that leverages next-generation sequencing and bioinformatics to guide personalized cancer treatment. It develops and provides a portfolio of tissue- and blood-based, NGS-driven therapy selection tests, including OncoScreen Plus, LungPlasma, ColonCore and HRDCore, and evaluates biomarkers such as microsatellite instability, tumor mutation burden, and NTRK fusions across multiple cancer types, including lung, gastrointestinal, prostate, breast, hematologic, thyroid, colorectal, ovarian, pancreatic, and bladder cancers. The company supports clinical and research use through one-stop services spanning genetic testing and companion diagnostic development, operating through central laboratory and in-hospital models. It collaborates with major pharmaceutical companies on clinical trials and research to advance targeted therapies and diagnostics. Founded in 2014, it is headquartered in Guangzhou, with a Guangzhou laboratory and an R&D center in Shanghai, reflecting its focus on expanding access to precision oncology in China.

Zai Lab is a biopharmaceutical company dedicated to discovering and developing transformative medicines for cancer, autoimmune, and infectious diseases. Founded in Shanghai in 2014, the company focuses on bringing innovative therapies to patients worldwide. Zai Lab's pipeline includes proprietary drug candidates such as Niraparib, Optune, Ripretinib, and Margetuximab, among others. The company collaborates with global biopharma leaders to expand its pipeline and foster innovation in China.

biomodal develops DNA sequencing tools and technology to enable advanced medicines, diagnostics, and personalized treatments. Its platform is designed to integrate with existing sequencing and computing platforms, enabling users to obtain complete genetic and epigenetic methylation information from DNA libraries in a single workflow.

Zai Lab is a biopharmaceutical company dedicated to discovering and developing transformative medicines for cancer, autoimmune, and infectious diseases. Founded in Shanghai in 2014, the company focuses on bringing innovative therapies to patients worldwide. Zai Lab's pipeline includes proprietary drug candidates such as Niraparib, Optune, Ripretinib, and Margetuximab, among others. The company collaborates with global biopharma leaders to expand its pipeline and foster innovation in China.

Koncen BioScience was founded by a group of Chinese who returned to the country after completing their educations overseas. This high-technology biomedical enterprise offers integrated research and development, along with manufacturing and marketing services, all focused on blood purification technologies and products.

BGI is a biotechnology company specializing in genomics. It provides genome sequencing and genetic testing services to research institutions and healthcare professionals worldwide. The company's offerings include bioinformatics, multi-omics solutions, and related tools, catering to a diverse range of clients such as pharmaceutical companies and academic institutions. BGI's work has contributed significantly to genetic and genomic research, with notable collaborations including Eli Lilly and Company, Merck, Pfizer Inc., and the Bill & Melinda Gates Foundation.

Founded in 2001, Celon Laboratories is a Hyderabad-based pharmaceutical company specializing in the development, manufacturing, and marketing of niche therapy products. Its portfolio includes oncology and critical care products, available in various dosage forms, serving markets across Asia Pacific, Africa, Latin America, CIS countries, and Eastern Europe.