Seroba Life Sciences

Founded in 2018, Perfuze is a medical device company based in Galway, Ireland. It specializes in developing catheter-based aspiration technology designed to treat acute ischemic stroke efficiently and effectively.

Coave Therapeutics specializes in developing gene therapies for rare ocular and central nervous system (CNS) diseases. Its platform enables targeted delivery of therapeutic genes to the CNS, enhancing autophagy and lysosomal function, with a focus on improving patient outcomes for conditions like ALS.

Deciphex is a digital pathology software company that blends AI with pathology expertise to streamline diagnostic workflows and support therapeutic development. Its Patholytix platform applies digital pathology and AI to preclinical and toxicologic pathology, triaging high-volume, low-complexity samples and accelerating preclinical safety assessments for pharma and clinical research. Its Diagnexia platform connects global subspecialty pathologists to deliver rapid diagnostics and reduce backlogs in clinical workflows. Founded in 2017, Deciphex is headquartered in Dublin, Ireland.

ShiraTronics develops neuromodulation therapies to treat chronic migraine by delivering continuous stimulation to targeted nerves to relieve, interrupt, and prevent migraine episodes. Founded in 2018 and based in Ireland, the company maintains an additional location in Minneapolis, Minnesota, and pursues innovative neuromodulation technology to address unmet neurological needs and improve patient outcomes.

Founded in 2017, Loci Orthopaedics specializes in developing innovative medical technologies for orthopedics. The company is renowned for its InDx implant, the only device that fully mimics natural thumb joint motions and offers a less invasive surgical treatment option.

Vico Therapeutics B.V. is a biotechnology company based in Leiden, the Netherlands, founded in 2019. The company specializes in the development of RNA modulating therapies aimed at treating rare neurological disorders. Vico Therapeutics focuses on conditions such as spinocerebellar ataxias, Huntington’s disease, and Rett syndrome, which encompass a range of hereditary and neurodevelopmental disorders. By discovering and developing innovative therapies, the company aims to address significant unmet medical needs in the central nervous system, providing new treatment options for patients and healthcare professionals.

Artica Therapeutics focuses on biotechnological research and development, specializing in novel therapies for severe autoimmune and inflammatory disorders. The company employs label-free cellular-based screening approaches to accelerate drug candidate progression, aiming to provide selective therapies for patients with unmet medical needs.

Shorla Pharma Limited is an Irish specialty pharmaceutical company focused on developing and manufacturing oncology drugs for orphan and pediatric cancers. Established in 2017 and headquartered in Clonmel, Ireland, with an additional office in New York, the company aims to provide accessible and affordable life-saving treatments. Its product portfolio includes SH-111, a sterile injectable solution designed to treat T-cell leukemia in both pediatric and adult patients, as well as SH-105, another oncology drug. Shorla Pharma is dedicated to enhancing patient care and making a significant clinical impact through its innovative therapies.

A preclinical-stage company developing a precision medicine diagnostic platform. This platform enables patient stratification based on complement-activation profiles, potentially serving as an efficacy biomarker in future clinical studies.

Deciphex is a digital pathology software company that blends AI with pathology expertise to streamline diagnostic workflows and support therapeutic development. Its Patholytix platform applies digital pathology and AI to preclinical and toxicologic pathology, triaging high-volume, low-complexity samples and accelerating preclinical safety assessments for pharma and clinical research. Its Diagnexia platform connects global subspecialty pathologists to deliver rapid diagnostics and reduce backlogs in clinical workflows. Founded in 2017, Deciphex is headquartered in Dublin, Ireland.

Storm Therapeutics Limited is a biotechnology company based in Cambridge, United Kingdom, focused on discovering and developing small molecule drugs that target RNA-modifying enzymes for cancer treatment and other immune diseases. Incorporated in 2015 and previously known as Iceni Therapeutics Limited, the company utilizes its drug discovery and RNA analytics platform to modulate RNA modifying enzymes, identifying novel targets and first-in-class drug candidates. Storm Therapeutics aims to provide innovative therapies against RNA epigenetic targets, addressing various conditions including oncology, inflammation, viral infections, and central nervous system diseases.

Sibylla Biotech S.R.L. is an Italian biotechnology company focused on the research and development of innovative solutions for drug design. The company specializes in producing small molecule folding interfering degraders (FIDs) that target various therapeutic areas. Sibylla Biotech employs advanced patent-based software that utilizes algorithms and drug design protocols to enhance drug discovery processes. By implementing original reaction path sampling and data reduction techniques, the software aims to streamline the development of treatments for incurable diseases. In addition to its product development, Sibylla Biotech offers consultancy services in biotechnology and drug development, supporting medical practitioners in rationalizing their research efforts. The company is headquartered in Italy.

Founded in 2018, Perfuze is a medical device company based in Galway, Ireland. It specializes in developing catheter-based aspiration technology designed to treat acute ischemic stroke efficiently and effectively.

Coave Therapeutics specializes in developing gene therapies for rare ocular and central nervous system (CNS) diseases. Its platform enables targeted delivery of therapeutic genes to the CNS, enhancing autophagy and lysosomal function, with a focus on improving patient outcomes for conditions like ALS.

Palliare is a medical technology company focused on advancing smoke insufflation and evacuation solutions tailored for various surgical applications, including robotic, laparoscopic, endoluminal, and colorectal procedures. The company offers products such as the EVA15 insufflator and a specialized smoke evacuation system, designed to enhance surgical workflows while safeguarding operating room staff from the dangers of surgical smoke and aerosolized viruses. Palliare aims to establish itself as a leader in the field of advanced insufflation technology, addressing the needs of minimally invasive surgery and providing hospitals with effective solutions for smoke management during surgical procedures.

Quanta is a medical devices company that develops advanced haemodialysis systems for use in the home and clinic. Quanta is focused on the commercialisation and ongoing development of SC+, an innovative cartridge-based haemodialysis system. SC+ is a high performance, compact haemodialysis system providing clinical efficacy by utilising typical flow rates of traditional in-centre machines. SC+ supports the entire ‘Continuum of Care’ for dialysis patients, from nurse-assisted treatment through self-care in centre to home haemodialysis. Their system facilitates the seamless transition between treatment modalities providing the best tool to enable flexibility for patients, and treatment options for physicians.

Atlantic Therapeutics Limited is a medical technology company based in Galway, Ireland, with additional offices in London, Paris, and Salem. Established in 2013, the company specializes in the manufacture and distribution of medical devices designed for pelvic floor muscle strengthening and nerve stimulation. Its key products include Innovotherapy, a device aimed at enhancing pelvic floor muscle function, and INNOVO, a wearable device specifically targeting stress urinary incontinence by addressing its underlying causes. Atlantic Therapeutics distributes its products through a network of distributors across Ireland, the United Kingdom, France, Germany, and the Middle East. The company operates as a subsidiary of Bio-Medical Research Limited.

Shorla Pharma Limited is an Irish specialty pharmaceutical company focused on developing and manufacturing oncology drugs for orphan and pediatric cancers. Established in 2017 and headquartered in Clonmel, Ireland, with an additional office in New York, the company aims to provide accessible and affordable life-saving treatments. Its product portfolio includes SH-111, a sterile injectable solution designed to treat T-cell leukemia in both pediatric and adult patients, as well as SH-105, another oncology drug. Shorla Pharma is dedicated to enhancing patient care and making a significant clinical impact through its innovative therapies.

Quanta is a medical devices company that develops advanced haemodialysis systems for use in the home and clinic. Quanta is focused on the commercialisation and ongoing development of SC+, an innovative cartridge-based haemodialysis system. SC+ is a high performance, compact haemodialysis system providing clinical efficacy by utilising typical flow rates of traditional in-centre machines. SC+ supports the entire ‘Continuum of Care’ for dialysis patients, from nurse-assisted treatment through self-care in centre to home haemodialysis. Their system facilitates the seamless transition between treatment modalities providing the best tool to enable flexibility for patients, and treatment options for physicians.

Storm Therapeutics Limited is a biotechnology company based in Cambridge, United Kingdom, focused on discovering and developing small molecule drugs that target RNA-modifying enzymes for cancer treatment and other immune diseases. Incorporated in 2015 and previously known as Iceni Therapeutics Limited, the company utilizes its drug discovery and RNA analytics platform to modulate RNA modifying enzymes, identifying novel targets and first-in-class drug candidates. Storm Therapeutics aims to provide innovative therapies against RNA epigenetic targets, addressing various conditions including oncology, inflammation, viral infections, and central nervous system diseases.

Fusion Pharmaceuticals is a clinical-stage biopharmaceutical company specializing in developing radiopharmaceuticals as precision medicines. It focuses on creating targeted alpha therapeutics using its proprietary linker technology to enhance the safety and efficacy of these drugs, ultimately improving cancer patient outcomes.

PQ Bypass is a medical device company based in Milpitas, California, focused on transforming the treatment of long-segment peripheral artery disease through minimally-invasive endovascular solutions. Founded in 2009, the company develops and manufactures devices such as the DETOUR System, PQ Snare, PQ Crossing Device, and TORUS Stent Graft System to treat peripheral vascular disease via percutaneous surgical bypass. The executive team at PQ Bypass includes recognized leaders from the medical device industry with extensive experience in developing innovative solutions for venture-backed startups and major corporations like Medtronic, Abbott, Johnson & Johnson, Covidien, and Stryker.

Atlantic Therapeutics Limited is a medical technology company based in Galway, Ireland, with additional offices in London, Paris, and Salem. Established in 2013, the company specializes in the manufacture and distribution of medical devices designed for pelvic floor muscle strengthening and nerve stimulation. Its key products include Innovotherapy, a device aimed at enhancing pelvic floor muscle function, and INNOVO, a wearable device specifically targeting stress urinary incontinence by addressing its underlying causes. Atlantic Therapeutics distributes its products through a network of distributors across Ireland, the United Kingdom, France, Germany, and the Middle East. The company operates as a subsidiary of Bio-Medical Research Limited.

Endotronix develops and manufactures implantable wireless pulmonary artery pressure sensors for early detection of worsening heart failure. The company's platform includes a cloud-based disease management data system, enabling remote patient monitoring.

Fusion Pharmaceuticals is a clinical-stage biopharmaceutical company specializing in developing radiopharmaceuticals as precision medicines. It focuses on creating targeted alpha therapeutics using its proprietary linker technology to enhance the safety and efficacy of these drugs, ultimately improving cancer patient outcomes.

Founded in 2009, Medlumics designs and manufactures catheter-based systems for treating supraventricular tachycardias. Utilizing optical coherence tomography technology, the company's products provide real-time, sectional information about tissue, enhancing procedural safety and efficacy.

Atlantic Therapeutics Limited is a medical technology company based in Galway, Ireland, with additional offices in London, Paris, and Salem. Established in 2013, the company specializes in the manufacture and distribution of medical devices designed for pelvic floor muscle strengthening and nerve stimulation. Its key products include Innovotherapy, a device aimed at enhancing pelvic floor muscle function, and INNOVO, a wearable device specifically targeting stress urinary incontinence by addressing its underlying causes. Atlantic Therapeutics distributes its products through a network of distributors across Ireland, the United Kingdom, France, Germany, and the Middle East. The company operates as a subsidiary of Bio-Medical Research Limited.

Prexton Therapeutics SA is a biopharmaceutical company based in Geneva, Switzerland, founded in 2012. It specializes in the development of innovative drugs for Parkinson's disease and other brain disorders. The company focuses on targeting metabotropic glutamate receptors, specifically mGluR4 and mGluR3, utilizing a novel scientific approach that integrates molecular, behavioral, and chemical technologies. Prexton Therapeutics aims to improve the quality of life for patients by offering alternatives to traditional dopaminergic treatments through its unique mGluR4 PAM series. This approach allows for quicker initiation of treatment, potentially leading to better medical outcomes for individuals suffering from these conditions.

Veryan Medical Ltd. is a UK-based company that specializes in the design and development of innovative vascular stent technology. Established in 2003 as a spin-out from Imperial College London, the company focuses on its proprietary BioMimics 3D technology, which employs biomimicry principles to enhance stent performance. This technology features a unique three-dimensional helical geometry that replicates natural curvature, promoting improved blood flow dynamics and reducing the risk of complications such as restenosis. Veryan Medical's stents are particularly aimed at treating patients with symptomatic peripheral arterial disease in the lower limbs, facilitating quicker initiation of treatment and potentially leading to better health outcomes. The company operates a research and development facility in Galway, Ireland, and, as of December 2018, is a subsidiary of Otsuka Medical Devices Co., Ltd.

Quanta is a medical devices company that develops advanced haemodialysis systems for use in the home and clinic. Quanta is focused on the commercialisation and ongoing development of SC+, an innovative cartridge-based haemodialysis system. SC+ is a high performance, compact haemodialysis system providing clinical efficacy by utilising typical flow rates of traditional in-centre machines. SC+ supports the entire ‘Continuum of Care’ for dialysis patients, from nurse-assisted treatment through self-care in centre to home haemodialysis. Their system facilitates the seamless transition between treatment modalities providing the best tool to enable flexibility for patients, and treatment options for physicians.

Heart Metabolics Limited is a pharmaceutical company focused on developing therapies for hypertrophic cardiomyopathy (HCM), a condition where the heart muscle thickens, making it harder for blood to leave the heart and often leading to heart failure or sudden death. With over 100,000 cases in the United States alone, HCM can be particularly severe in young adults and athletes. Current cardiovascular drugs do not help all patients, highlighting a significant medical need. Heart Metabolics is addressing this by developing perhexiline, an approved drug in Australia and New Zealand for angina, as a therapeutic for all types of HCM. The company plans to conduct clinical trials in the U.S. and seek FDA approval for perhexiline as an orphan drug, which it has already designated.

Apica Cardiovascular is a pre-revenue medical device company specializing in a technology for accessing and closing the heart's apex and peripheral vascular system. This technology standardizes access and closure for large bore therapeutic devices without blood loss, enabling minimally invasive surgical or percutaneous procedures on the beating heart. It has applications in Transcatheter Heart Valves (TAVI), Abdominal Aortic Aneurysm (AAA) repair, and Left Ventricular Assist Device (LVAD) implantation. After successful animal and cadaver model testing, the technology is now advancing towards initial clinical trials.

Covagen is a biopharmaceutical company specializing in the development of bispecific therapeutics known as FynomAbs, which are created by genetically fusing human Fynomer binding proteins to antibodies. This innovative approach allows Covagen to design therapeutics with unique architectures, enhancing their efficacy in treating inflammatory diseases and cancer. The company aims to explore novel biological pathways with each product candidate, with its lead FynomAb, COVA322, currently being developed for inflammatory conditions such as rheumatoid arthritis and psoriatic arthritis. Founded in 2007 as a spin-off from ETH Zurich, Covagen has established strategic collaborations, notably with Mitsubishi Tanabe, to advance its drug development initiatives. The company is supported by a diverse group of investors committed to its research and therapeutic programs.

Biosensia Ltd. is a Dublin-based company specializing in point-of-care in-vitro diagnostics. It has developed RapiPlex, an innovative diagnostic system designed to deliver both quantitative and qualitative laboratory test results. This system features a disposable assay cartridge and a compact tabletop instrument, allowing for the transition of complex immunoassays from centralized laboratories to doctors' offices or patients' bedsides. RapiPlex facilitates near-patient care by providing rapid and practical testing solutions across various applications, including theranostic identification and monitoring, as well as veterinary and food safety testing. The platform is compatible with multiple biological sample types, such as whole blood, plasma, serum, urine, saliva, and milk. Founded in 2000 and previously known as NanoComms Ltd., Biosensia Ltd. rebranded in 2006 and currently operates as a subsidiary of Kypha Inc.

Veryan Medical Ltd. is a UK-based company that specializes in the design and development of innovative vascular stent technology. Established in 2003 as a spin-out from Imperial College London, the company focuses on its proprietary BioMimics 3D technology, which employs biomimicry principles to enhance stent performance. This technology features a unique three-dimensional helical geometry that replicates natural curvature, promoting improved blood flow dynamics and reducing the risk of complications such as restenosis. Veryan Medical's stents are particularly aimed at treating patients with symptomatic peripheral arterial disease in the lower limbs, facilitating quicker initiation of treatment and potentially leading to better health outcomes. The company operates a research and development facility in Galway, Ireland, and, as of December 2018, is a subsidiary of Otsuka Medical Devices Co., Ltd.

NOvate Medical Technologies is a medical device development company based in New Orleans, dedicated to creating high-quality, low-cost, and sustainable medical products that address pressing global health challenges. The company's flagship product, InfaClip, is a patented disposable obstetric device designed to simultaneously cut, clamp, and shield the infant, mother, and birthing attendant from potential infections. This innovative device aims to significantly reduce maternal and neonatal mortality rates, particularly in developing countries, by enhancing the safety of childbirth and allowing healthcare professionals to manage clots effectively. Through its focus on affordability and sustainability, NOvate Medical Technologies strives to improve healthcare outcomes in underserved communities.

Provesica is a Cambridge-based biopharmaceutical company specialising in overactive bladder. The Company’s development compound, XEN-D0501, is highly potent antagonist of the vanilloid receptor, TRPV1, and is about to start Phase 2 clinical development. In addition to XEN-D0501, Provesica owns a portfolio of intellectual property covering diverse TRPV1 antagonists suitable for development in overactive bladder or other indications where TRPV1 has been validated as an intervention target. Provesica was established in 2010 following the demerger of the overactive bladder and TRPV1 interests of Xention Ltd, an ion channel specialist drug discovery and development company. Provesica has so far raised £4 million in finance to progress its lead programme through Phase 2 development.

Covagen is a biopharmaceutical company specializing in the development of bispecific therapeutics known as FynomAbs, which are created by genetically fusing human Fynomer binding proteins to antibodies. This innovative approach allows Covagen to design therapeutics with unique architectures, enhancing their efficacy in treating inflammatory diseases and cancer. The company aims to explore novel biological pathways with each product candidate, with its lead FynomAb, COVA322, currently being developed for inflammatory conditions such as rheumatoid arthritis and psoriatic arthritis. Founded in 2007 as a spin-off from ETH Zurich, Covagen has established strategic collaborations, notably with Mitsubishi Tanabe, to advance its drug development initiatives. The company is supported by a diverse group of investors committed to its research and therapeutic programs.

Veryan Medical Ltd. is a UK-based company that specializes in the design and development of innovative vascular stent technology. Established in 2003 as a spin-out from Imperial College London, the company focuses on its proprietary BioMimics 3D technology, which employs biomimicry principles to enhance stent performance. This technology features a unique three-dimensional helical geometry that replicates natural curvature, promoting improved blood flow dynamics and reducing the risk of complications such as restenosis. Veryan Medical's stents are particularly aimed at treating patients with symptomatic peripheral arterial disease in the lower limbs, facilitating quicker initiation of treatment and potentially leading to better health outcomes. The company operates a research and development facility in Galway, Ireland, and, as of December 2018, is a subsidiary of Otsuka Medical Devices Co., Ltd.

Quanta is a medical devices company that develops advanced haemodialysis systems for use in the home and clinic. Quanta is focused on the commercialisation and ongoing development of SC+, an innovative cartridge-based haemodialysis system. SC+ is a high performance, compact haemodialysis system providing clinical efficacy by utilising typical flow rates of traditional in-centre machines. SC+ supports the entire ‘Continuum of Care’ for dialysis patients, from nurse-assisted treatment through self-care in centre to home haemodialysis. Their system facilitates the seamless transition between treatment modalities providing the best tool to enable flexibility for patients, and treatment options for physicians.

Opsona Therapeutics is a Dublin-based drug development company specializing in immunology, particularly the modulation of innate immunity pathways. Founded in 2004, the company has developed innovative therapeutic approaches aimed at treating autoimmune and inflammatory diseases, as well as cancer. By targeting the innate immune system, Opsona addresses a spectrum of significant health challenges, including transplant rejection, diabetes, Alzheimer's disease, and atherosclerosis. The company seeks to improve patient outcomes through its novel drug candidates and strategies, positioning itself as a leader in emerging immunology research and drug development in Europe.

Opsona Therapeutics is a Dublin-based drug development company specializing in immunology, particularly the modulation of innate immunity pathways. Founded in 2004, the company has developed innovative therapeutic approaches aimed at treating autoimmune and inflammatory diseases, as well as cancer. By targeting the innate immune system, Opsona addresses a spectrum of significant health challenges, including transplant rejection, diabetes, Alzheimer's disease, and atherosclerosis. The company seeks to improve patient outcomes through its novel drug candidates and strategies, positioning itself as a leader in emerging immunology research and drug development in Europe.

Biosensia Ltd. is a Dublin-based company specializing in point-of-care in-vitro diagnostics. It has developed RapiPlex, an innovative diagnostic system designed to deliver both quantitative and qualitative laboratory test results. This system features a disposable assay cartridge and a compact tabletop instrument, allowing for the transition of complex immunoassays from centralized laboratories to doctors' offices or patients' bedsides. RapiPlex facilitates near-patient care by providing rapid and practical testing solutions across various applications, including theranostic identification and monitoring, as well as veterinary and food safety testing. The platform is compatible with multiple biological sample types, such as whole blood, plasma, serum, urine, saliva, and milk. Founded in 2000 and previously known as NanoComms Ltd., Biosensia Ltd. rebranded in 2006 and currently operates as a subsidiary of Kypha Inc.

TriMed Research, Inc. engages in the research and development of therapeutic products primarily related to mammary gland protein designated as MAA.

Diabetica Ltd was established in September 2004 to commercialise discoveries at the Diabetes Research Group in the University of Ulster, under the leadership of scientific co-founders Prof Peter Flatt, Dr Neville McClenaghan and Prof Finbarr O'Harte.

Opsona Therapeutics is a Dublin-based drug development company specializing in immunology, particularly the modulation of innate immunity pathways. Founded in 2004, the company has developed innovative therapeutic approaches aimed at treating autoimmune and inflammatory diseases, as well as cancer. By targeting the innate immune system, Opsona addresses a spectrum of significant health challenges, including transplant rejection, diabetes, Alzheimer's disease, and atherosclerosis. The company seeks to improve patient outcomes through its novel drug candidates and strategies, positioning itself as a leader in emerging immunology research and drug development in Europe.

Azafaros develops therapeutic agents for treating rare metabolic disorders, specifically lysosomal storage disorders (LSDs), via oral administration of azasugar compounds. These innovative agents were discovered by Professor Hans Aerts and are licensed exclusively to Azafaros.