SkyRiver Ventures

Holobiome is a biotechnology company based in Cambridge, Massachusetts, founded in 2015. The company focuses on developing microbiome-based therapeutics aimed at addressing diseases of the enteric and central nervous systems. Holobiome's innovative approach involves mapping and manipulating the gut-brain axis through next-generation probiotics, enabling the treatment of mental health disorders such as depression and anxiety, as well as enhancing metabolic and immune responses. By leveraging insights into the human gut microbiome, Holobiome seeks to provide effective therapies that allow patients to recover from their conditions with minimal discomfort.

Material Evolution is a manufacturing enterprise dedicated to reducing greenhouse gas emissions in the cement industry. It employs artificial intelligence and machine learning to innovate a low-cost, energy-efficient production process for sustainable concrete, utilizing hyper-local waste streams as primary materials. This approach enables the construction sector to meet its sustainability objectives while offering a viable alternative to traditional Ordinary Portland Cement (OPC).

Geminus.AI, Inc. is a company based in Palo Alto, California, that specializes in developing artificial intelligence systems tailored for industrial processes. Founded in 1990, Geminus creates a platform designed to empower engineers and industrial operators to make rapid and informed decisions in environments characterized by high uncertainty. The company's offerings focus on self-optimized design and predictive operational intelligence, enhancing the performance and efficiency of various industrial assets, including refineries, power plants, satellites, and ships. By leveraging advanced AI applications, Geminus aims to support operators and engineering service providers in improving their operational capabilities.