SkyRiver Ventures

Holobiome is a biotechnology company based in Cambridge, Massachusetts, focused on developing microbiome-based therapeutics for treating diseases of the enteric and central nervous systems. Established in 2015, the company aims to address mental health issues such as depression and anxiety by leveraging the gut-brain axis through next-generation probiotics. By mapping and manipulating the human gut microbiome, Holobiome provides healthcare providers with innovative interventions that enhance patient recovery and improve metabolic and immune responses, all while minimizing pain and suffering associated with these conditions.

Material Evolution is a manufacturing company focused on decarbonizing the cement industry through innovative technology. It specializes in producing smart and sustainable concrete that significantly reduces carbon dioxide emissions. By leveraging artificial intelligence and machine learning, the company transforms material chemistry to create a sustainable cement replacement sourced from hyper-local waste streams. This low-capital expenditure, low-energy manufacturing process allows the construction industry to adopt a more sustainable alternative to traditional ordinary Portland cement, helping businesses meet their environmental goals effectively.

Geminus.AI, Inc. is a company based in Palo Alto, California, that specializes in developing artificial intelligence systems tailored for industrial processes. Founded in 1990, Geminus creates a platform designed to empower engineers and industrial operators to make rapid and informed decisions in environments characterized by high uncertainty. The company's offerings focus on self-optimized design and predictive operational intelligence, enhancing the performance and efficiency of various industrial assets, including refineries, power plants, satellites, and ships. By leveraging advanced AI applications, Geminus aims to support operators and engineering service providers in improving their operational capabilities.