SOSV

Particle Industries, Inc. is a provider of a comprehensive platform designed for the prototyping, scaling, and management of Internet of Things (IoT) products. The company offers a range of hardware development kits, including the Photon for Wi-Fi projects and the Electron for cellular-connected devices, along with various accessories like antennas and USB shields. Particle also delivers software tools such as Tinker, a mobile application for remote control, and Particle Build, a web-based development environment that allows users to write and deploy code easily. Its cloud platform facilitates secure interactions with connected devices through modern APIs, supporting developers in creating intelligent web services. With over 150,000 product builders across more than 170 countries, including notable clients like NASA and SpaceX, Particle has established itself as a key player in the IoT landscape. Founded in 2012 and headquartered in San Francisco, California, with an additional office in Shenzhen, China, the company has been recognized for its innovation and impact in the IoT sector.

Prellis Biologics is a biotechnology company based in San Francisco, founded in 2016, focused on bioprinting vascularized human tissues and organs for drug development, disease modeling, and transplantation. Its platform enables rapid, high-resolution printing of tissues and organoids, including lymph node models, to reproduce human immune responses. This capability supports antibody discovery, immunogenicity assessment, and tumor–immune studies, aiming to accelerate early-stage drug discovery and translational pharmacology while advancing the development of tissue and organ therapies.

Founded in 2016, Abbot's Butcher produces high-quality, small-batch plant-based meat products. Their allergen-friendly range includes items like chopped chick'n, beef sausage, and chorizo, crafted from whole food ingredients.

Tensorfield Agriculture is a company based in San Jose, California, specializing in the development and manufacture of advanced agricultural machinery tailored for specialty row crops. Founded in 2018, the company focuses on innovative solutions that promote sustainable farming practices in a post-herbicide environment. Tensorfield Agriculture's machinery includes robots equipped with computer vision technology that perform selective, non-invasive weeding through thermal micro-dosing techniques. This approach helps farmers combat herbicide resistance while ensuring the continued supply of safe and sustainable fresh food. The company's commitment to enhancing agricultural efficiency positions it at the forefront of modern farming solutions.

Founded in 2023, AlkaLi Labs is a biotechnology company based in San Francisco. It specializes in recovering critical minerals like lithium and cobalt from industrial waste streams using bioengineering solutions.

Renewell, headquartered in Bakersfield, California, specializes in repurposing idle oil and gas wells into gravity-based energy storage systems. Their technology involves lowering a weight connected to a regenerative winch down an abandoned wellbore during periods of low demand, storing potential energy, and raising it back up when demand is high, releasing electricity onto the grid. This innovative approach helps reduce greenhouse gas emissions by transforming inactive oil and gas infrastructure into flexible renewable energy storage solutions.

OneSkin is a biotechnology company focused on skin aging and longevity that develops testing platforms and consumer products. It uses animal-free three-dimensional human skin models to evaluate the safety and efficacy of cosmetic ingredients and anti-aging compounds, supporting research and validation for the cosmetic and ingredient supplier industries. The company has developed a proprietary peptide, OS-01, intended to reduce skin biological age by decreasing the accumulation of aged cells, improving cellular repair, and strengthening the epidermal barrier. Its consumer offering includes a vegan topical product based on OS-01 designed for all skin types, marketed through its website. The business combines in vitro testing services with product development to address root causes of skin aging and support proper skin cell function.

Founded in 2022 and headquartered in Berkeley, California, Laguna Bio develops a drug discovery platform designed to selectively activate and expand the innate immune system against cancer. The company focuses on providing a specific type of T cell for the immune system to fight solid tumors by increasing the response rate of bispecific antibody drugs.

Founded in 2021, Sóliome is a biotechnology company based in San Francisco, California. It specializes in developing protein-based sunscreens that are safe and effective, using molecules naturally produced by the human body to protect against harmful UV rays.

Tensorfield Agriculture is a company based in San Jose, California, specializing in the development and manufacture of advanced agricultural machinery tailored for specialty row crops. Founded in 2018, the company focuses on innovative solutions that promote sustainable farming practices in a post-herbicide environment. Tensorfield Agriculture's machinery includes robots equipped with computer vision technology that perform selective, non-invasive weeding through thermal micro-dosing techniques. This approach helps farmers combat herbicide resistance while ensuring the continued supply of safe and sustainable fresh food. The company's commitment to enhancing agricultural efficiency positions it at the forefront of modern farming solutions.

Unspun, Inc. is a digital apparel company based in San Francisco, California, founded in 2015. It specializes in creating custom jeans tailored to individual consumers using advanced body scanning technology, fit algorithms, and additive manufacturing. The company aims to address environmental challenges by minimizing pattern-cutting waste and unsold inventory, thus contributing to a reduction in global carbon emissions. Unspun's innovative approach enables on-demand production of jeans in under ten minutes, utilizing localized manufacturing processes designed to be zero-waste. Its technology has gained recognition, including being named one of TIME's Best Inventions of 2019, and supports a B2B platform that facilitates digital customization for major apparel brands.

Situated in San Francisco, California, the company is presently functioning in stealth mode.

Kegg is a company that specializes in women's health, focusing on fertility tracking and pelvic floor exercising. Established in 2017 and based in San Francisco, California, Kegg has developed an innovative device that combines these two aspects into a single, user-friendly product. The device effectively tracks changes in vaginal and cervical fluids, enabling users to identify their fertile window and predict ovulation up to seven days in advance. This capability significantly enhances the chances of natural conception by providing women with crucial data to support informed decisions regarding their reproductive health. By implementing advanced sensing technology, Kegg aims to improve diagnosis, monitoring, and treatment related to women's fertility.

Particle Industries, Inc. is a provider of a comprehensive platform designed for the prototyping, scaling, and management of Internet of Things (IoT) products. The company offers a range of hardware development kits, including the Photon for Wi-Fi projects and the Electron for cellular-connected devices, along with various accessories like antennas and USB shields. Particle also delivers software tools such as Tinker, a mobile application for remote control, and Particle Build, a web-based development environment that allows users to write and deploy code easily. Its cloud platform facilitates secure interactions with connected devices through modern APIs, supporting developers in creating intelligent web services. With over 150,000 product builders across more than 170 countries, including notable clients like NASA and SpaceX, Particle has established itself as a key player in the IoT landscape. Founded in 2012 and headquartered in San Francisco, California, with an additional office in Shenzhen, China, the company has been recognized for its innovation and impact in the IoT sector.

Founded in 2020, Prolific Machines is a San Francisco-based biotech company dedicated to revolutionizing cell production for a sustainable future. It combines advanced technologies to enable large-scale cell manufacturing, aiming to improve therapeutic protein production for biotechnology and pharmaceutical companies.

Lief Therapeutics is a medical device company based in San Francisco, California, focused on enhancing at-home care for individuals dealing with post-traumatic stress disorder, depression, and anxiety. The company has developed a discreet bio-sensing patch that accurately measures heart rate and breath, allowing users to manage their natural stress response through vibratory biofeedback exercises. This wearable device helps users monitor their behaviors, emotions, and thoughts in real-time, fostering mindfulness and control throughout the day. Additionally, it supports clinicians by tracking patient progress, facilitating in-session training, and scheduling psychological assessments. Lief Therapeutics also offers the Lief Health Score application, which records thoughts, emotions, and sensations, enabling users to track daily progress and engage in tailored exercises. Founded in 2014, the company sells its products online, aiming to empower individuals in their mental health journeys.

Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on cultivating marine-animal cells to create sustainable fish and seafood alternatives, including bluefin tuna. Finless Foods aims to provide a variety of food options that cater to diverse tastes and dietary preferences while promoting responsible production practices. By offering accessible plant-based and cell-cultured seafood alternatives, the company seeks to contribute to better ocean health and foster a more sustainable future for food consumption.

California Organic Fertilizers is a manufacturer of organic input materials that comply with Food Safety and National Organic Program standards. The company produces certified agricultural organic fertilizers designed to provide farmers with high plant-available nitrogen suitable for organic farming. Specializing in both liquid and dry fertilizers, California Organic Fertilizers sources its raw materials locally to support regional economies. The company is committed to the well-being of its workforce, communities, and the environment, ensuring that its products can be effectively used in organic farming operations and commercial landscape applications.

California Cultured is a food company based in Davis, California, that specializes in creating sustainable, lab-grown cocoa and coffee through advanced cellular agriculture techniques. Founded in 2020, the company focuses on producing cocoa that is less bitter and requires less sugar, while also ensuring its products are healthier for consumers. By stimulating cocoa cell growth using common food ingredients, California Cultured aims to provide high-quality cocoa products that are free from the ethical issues traditionally associated with cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious and sustainable cocoa without the environmental and social drawbacks of conventional methods.

Avisa Myko is a biotechnology company based in San Francisco, California. It specializes in the production of melanin, a natural pigment with applications in cosmetics, biomedicine, organic semiconductors, biosensors, and latex products. The company's patented technology enables large-scale production of soluble, affordable melanin, offering protection against ionizing radiation and contributing to better health and environmental sustainability.

Founded in 2013, ZymoChem develops eco-friendly chemical production processes using engineered microbes. These processes convert renewable feedstocks like sugars into industrial chemicals, minimizing carbon loss and enabling cost-competitive bio-based manufacturing.

Perfect Day, Inc. is a pioneering company based in Emeryville, California, that specializes in producing animal-free dairy products. Founded in 2014, the company creates milk, cheese, yogurt, milk proteins, and ice cream that are nutritionally identical to traditional dairy but are made through a fermentation process using plant-based sugars. This innovative approach allows Perfect Day to deliver products that retain the taste, texture, and nutrition of conventional dairy while eliminating concerns related to food safety, environmental impact, and animal welfare. The company's commitment to sustainability and compassion results in nutrient-dense alternatives that are vegan, free from antibiotics, cholesterol, and lactose, catering to a growing market for healthier and more ethical food options.

Chronus Health develops a portable diagnostic device for delivering point-of-care lab results in minutes. Its device enables real-time diagnosis at the point-of-care, improving time to care and patient outcomes.

Tensorfield Agriculture is a company based in San Jose, California, specializing in the development and manufacture of advanced agricultural machinery tailored for specialty row crops. Founded in 2018, the company focuses on innovative solutions that promote sustainable farming practices in a post-herbicide environment. Tensorfield Agriculture's machinery includes robots equipped with computer vision technology that perform selective, non-invasive weeding through thermal micro-dosing techniques. This approach helps farmers combat herbicide resistance while ensuring the continued supply of safe and sustainable fresh food. The company's commitment to enhancing agricultural efficiency positions it at the forefront of modern farming solutions.

Founded in 2014, Lingrove specializes in manufacturing eco-friendly bio-composite materials. Utilizing a proprietary process, they produce high-performance natural fiber composites from plant-based fibers and resins, aiming to reduce deforestation and embodied carbon in industries such as commercial interiors, transportation, and construction.

Prellis Biologics is a biotechnology company based in San Francisco, founded in 2016, focused on bioprinting vascularized human tissues and organs for drug development, disease modeling, and transplantation. Its platform enables rapid, high-resolution printing of tissues and organoids, including lymph node models, to reproduce human immune responses. This capability supports antibody discovery, immunogenicity assessment, and tumor–immune studies, aiming to accelerate early-stage drug discovery and translational pharmacology while advancing the development of tissue and organ therapies.

ViaBot Inc. specializes in developing autonomous outdoor robots tailored for commercial maintenance tasks. Founded in 2016 and headquartered in Sunnyvale, California, the company offers multi-functional robots that address various outdoor responsibilities, including sweeping, lawn mowing, and security. Their RUNO robots utilize advanced vision technology to monitor and scan properties, such as recognizing vehicle license plates. ViaBot's autonomous solutions feature modular technology, round-the-clock monitoring, easy scheduling, and long operational runtimes, thus enabling businesses like shopping malls and sports arenas to efficiently manage their outdoor environments. The company's commitment to ongoing updates ensures their robots remain effective and adaptable to changing needs.

Particle Industries, Inc. is a provider of a comprehensive platform designed for the prototyping, scaling, and management of Internet of Things (IoT) products. The company offers a range of hardware development kits, including the Photon for Wi-Fi projects and the Electron for cellular-connected devices, along with various accessories like antennas and USB shields. Particle also delivers software tools such as Tinker, a mobile application for remote control, and Particle Build, a web-based development environment that allows users to write and deploy code easily. Its cloud platform facilitates secure interactions with connected devices through modern APIs, supporting developers in creating intelligent web services. With over 150,000 product builders across more than 170 countries, including notable clients like NASA and SpaceX, Particle has established itself as a key player in the IoT landscape. Founded in 2012 and headquartered in San Francisco, California, with an additional office in Shenzhen, China, the company has been recognized for its innovation and impact in the IoT sector.

Founded in 2014, QuantumCyte develops an automated tissue dissection system that uses digital maps to isolate regions of interest containing informative biomarkers. This platform aims to improve cancer outcomes by enabling precise cellular data analysis for predicting drug efficacy.

Avisa Myko is a biotechnology company based in San Francisco, California. It specializes in the production of melanin, a natural pigment with applications in cosmetics, biomedicine, organic semiconductors, biosensors, and latex products. The company's patented technology enables large-scale production of soluble, affordable melanin, offering protection against ionizing radiation and contributing to better health and environmental sustainability.

Renewell, headquartered in Bakersfield, California, specializes in repurposing idle oil and gas wells into gravity-based energy storage systems. Their technology involves lowering a weight connected to a regenerative winch down an abandoned wellbore during periods of low demand, storing potential energy, and raising it back up when demand is high, releasing electricity onto the grid. This innovative approach helps reduce greenhouse gas emissions by transforming inactive oil and gas infrastructure into flexible renewable energy storage solutions.

Unspun, Inc. is a digital apparel company based in San Francisco, California, founded in 2015. It specializes in creating custom jeans tailored to individual consumers using advanced body scanning technology, fit algorithms, and additive manufacturing. The company aims to address environmental challenges by minimizing pattern-cutting waste and unsold inventory, thus contributing to a reduction in global carbon emissions. Unspun's innovative approach enables on-demand production of jeans in under ten minutes, utilizing localized manufacturing processes designed to be zero-waste. Its technology has gained recognition, including being named one of TIME's Best Inventions of 2019, and supports a B2B platform that facilitates digital customization for major apparel brands.

Founded in 2019, Karma Biotechnologies is a Los Angeles-based company dedicated to developing therapies for autoimmune diseases, allergies, and food sensitivities. It specializes in antigen-specific immunotherapies using lipid nanoparticle engineering.

California Cultured is a food company based in Davis, California, that specializes in creating sustainable, lab-grown cocoa and coffee through advanced cellular agriculture techniques. Founded in 2020, the company focuses on producing cocoa that is less bitter and requires less sugar, while also ensuring its products are healthier for consumers. By stimulating cocoa cell growth using common food ingredients, California Cultured aims to provide high-quality cocoa products that are free from the ethical issues traditionally associated with cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious and sustainable cocoa without the environmental and social drawbacks of conventional methods.

Founded in 2023, AlkaLi Labs is a biotechnology company based in San Francisco. It specializes in recovering critical minerals like lithium and cobalt from industrial waste streams using bioengineering solutions.

Prime Roots is a San Francisco-based company founded in 2017 that specializes in producing plant-based food products as alternatives to meat and seafood. The company utilizes natural koji proteins derived from fungi to create vegetarian-based super protein foods, such as salmon burgers, which mimic the taste, texture, and nutritional value of animal-derived products. By offering these alternatives, Prime Roots aims to reduce carbon-intensive reliance on animals and provide both meat-eaters and vegans with access to protein-rich food options. The company also organizes food events for its members and serves the broader food sector.

Founded in 2023, League of Play is an interactive entertainment platform based in Los Angeles, California. It connects creators and athletes to produce engaging content with integrated e-commerce features.

Geltor designs and produces animal-free collagen and other bioactive proteins for beauty, wellness, and nutrition applications. Founded in 2015, the company uses proprietary AI to create customized proteins tailored to specific industry needs.

Stämm Biotech is a San Francisco-based company specializing in advanced bioproduction systems designed to address the scaling challenges in the biotech industry. Founded in 2014, Stämm has developed an innovative biomanufacturing solution that integrates microfluidics, electroporation, and robotics, resulting in a compact, all-in-one Bioprocessor. This system has demonstrated productivity levels at least 70 times greater than traditional bioreactors, enabling clients to miniaturize bioreactors and optimize conditions more efficiently. Stämm's technology incorporates various sensors to monitor biological, physical, and chemical variations throughout the bioprocess, facilitating a streamlined approach to microbial growth and monoclonal cell line development. By transforming large-scale biotech operations into a more manageable micro-factory network, Stämm aims to unlock significant market potential in the coming years.

Pulse Industrial is a California-based company founded in 2017 that specializes in developing advanced monitoring solutions for industrial plants. The company focuses on creating sensors and devices that provide a comprehensive view of common valves and steam traps, which are critical components of steam generation processes. Pulse Industrial's flagship product, QALM, utilizes artificial intelligence to detect and monitor steam leaks by analyzing vibration and acoustic behavior. This innovative technology enables real-time alerts to maintenance personnel, facilitating timely interventions and enhancing operational safety. By leveraging low power wide area communication, Pulse Industrial's solutions aim to optimize energy efficiency and reduce fuel consumption across various industrial applications.

Windfall Bio is an innovative company based in San Mateo, California, that addresses climate change by transforming harmful methane emissions into organic fertilizer. Established in 2022, the company utilizes methane-eating microbes to capture methane from various sources, including agriculture, oil and gas, and waste management. This nature-based technology not only reduces the methane footprint of these industries but also improves their operational efficiency and profitability while minimizing the negative environmental impacts associated with synthetic fertilizers. By providing farmers and other producers with the means to convert methane into valuable soil nutrients, Windfall Bio fosters a sustainable agricultural future and contributes positively to environmental conservation. The company is backed by prominent venture capital firms, reflecting its potential to make a significant impact in the fight against climate change.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing innovative gene therapy treatments for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes advanced oral lipid nanoparticle technology to deliver mRNA and plasmid DNA directly to intestinal stem cells. This approach aims to address the root causes of gastrointestinal diseases, including Familial Adenomatous Polyposis (FAP), a hereditary condition that can lead to colorectal cancer and often necessitates invasive surgical interventions. DNALite's therapies seek to transform protein biologics into oral drugs, allowing for more effective and less invasive treatment options.

Lief Therapeutics is a medical device company based in San Francisco, California, focused on enhancing at-home care for individuals dealing with post-traumatic stress disorder, depression, and anxiety. The company has developed a discreet bio-sensing patch that accurately measures heart rate and breath, allowing users to manage their natural stress response through vibratory biofeedback exercises. This wearable device helps users monitor their behaviors, emotions, and thoughts in real-time, fostering mindfulness and control throughout the day. Additionally, it supports clinicians by tracking patient progress, facilitating in-session training, and scheduling psychological assessments. Lief Therapeutics also offers the Lief Health Score application, which records thoughts, emotions, and sensations, enabling users to track daily progress and engage in tailored exercises. Founded in 2014, the company sells its products online, aiming to empower individuals in their mental health journeys.

Tensorfield Agriculture is a company based in San Jose, California, specializing in the development and manufacture of advanced agricultural machinery tailored for specialty row crops. Founded in 2018, the company focuses on innovative solutions that promote sustainable farming practices in a post-herbicide environment. Tensorfield Agriculture's machinery includes robots equipped with computer vision technology that perform selective, non-invasive weeding through thermal micro-dosing techniques. This approach helps farmers combat herbicide resistance while ensuring the continued supply of safe and sustainable fresh food. The company's commitment to enhancing agricultural efficiency positions it at the forefront of modern farming solutions.

Particle Industries, Inc. is a provider of a comprehensive platform designed for the prototyping, scaling, and management of Internet of Things (IoT) products. The company offers a range of hardware development kits, including the Photon for Wi-Fi projects and the Electron for cellular-connected devices, along with various accessories like antennas and USB shields. Particle also delivers software tools such as Tinker, a mobile application for remote control, and Particle Build, a web-based development environment that allows users to write and deploy code easily. Its cloud platform facilitates secure interactions with connected devices through modern APIs, supporting developers in creating intelligent web services. With over 150,000 product builders across more than 170 countries, including notable clients like NASA and SpaceX, Particle has established itself as a key player in the IoT landscape. Founded in 2012 and headquartered in San Francisco, California, with an additional office in Shenzhen, China, the company has been recognized for its innovation and impact in the IoT sector.

Founded in 2020, Prolific Machines is a San Francisco-based biotech company dedicated to revolutionizing cell production for a sustainable future. It combines advanced technologies to enable large-scale cell manufacturing, aiming to improve therapeutic protein production for biotechnology and pharmaceutical companies.

Renewell, headquartered in Bakersfield, California, specializes in repurposing idle oil and gas wells into gravity-based energy storage systems. Their technology involves lowering a weight connected to a regenerative winch down an abandoned wellbore during periods of low demand, storing potential energy, and raising it back up when demand is high, releasing electricity onto the grid. This innovative approach helps reduce greenhouse gas emissions by transforming inactive oil and gas infrastructure into flexible renewable energy storage solutions.

OneSkin is a biotechnology company focused on skin aging and longevity that develops testing platforms and consumer products. It uses animal-free three-dimensional human skin models to evaluate the safety and efficacy of cosmetic ingredients and anti-aging compounds, supporting research and validation for the cosmetic and ingredient supplier industries. The company has developed a proprietary peptide, OS-01, intended to reduce skin biological age by decreasing the accumulation of aged cells, improving cellular repair, and strengthening the epidermal barrier. Its consumer offering includes a vegan topical product based on OS-01 designed for all skin types, marketed through its website. The business combines in vitro testing services with product development to address root causes of skin aging and support proper skin cell function.

Michroma is a biotech company that develops natural, thermostable colorants for fungus-based food and cosmetics by leveraging fermentation of filamentous fungi and synthetic biology. It aims to replace synthetic pigments with natural pigments produced through biotechnological fermentation, delivering pH- and heat-stable colorants at scale for food and cosmetic applications. The company operates in multiple locations, including San Francisco, United States, and Rosario, Argentina, and pursues scalable production in bioreactors using proprietary fungal strains.

Founded in 2022 and headquartered in Berkeley, California, Laguna Bio develops a drug discovery platform designed to selectively activate and expand the innate immune system against cancer. The company focuses on providing a specific type of T cell for the immune system to fight solid tumors by increasing the response rate of bispecific antibody drugs.

Filtricine, Inc., founded in 2017 and based in Santa Clara, California, is a clinical-stage biotechnology company focused on developing innovative therapies for cancer treatment. The company's approach involves targeted nutrient deprivation, which identifies and exploits metabolic vulnerabilities specific to cancer cells. By depleting nutrients critical to cancer growth without using traditional drugs, Filtricine aims to provide effective treatments that minimize harm to healthy cells.

Renewell, headquartered in Bakersfield, California, specializes in repurposing idle oil and gas wells into gravity-based energy storage systems. Their technology involves lowering a weight connected to a regenerative winch down an abandoned wellbore during periods of low demand, storing potential energy, and raising it back up when demand is high, releasing electricity onto the grid. This innovative approach helps reduce greenhouse gas emissions by transforming inactive oil and gas infrastructure into flexible renewable energy storage solutions.

Melio is a healthcare company based in Santa Clara, California, specializing in blood testing technology aimed at detecting prevalent infections. The company has developed a comprehensive blood test platform that identifies common pathogens responsible for bloodstream infections. Utilizing a patented melting technique followed by detailed analysis, Melio's technology enables quick and accurate identification of blood-based pathogens. This innovation allows healthcare providers to deliver timely and targeted treatment, addressing the urgent need for effective therapies while also contributing to the fight against antibiotic resistance.

Prellis Biologics is a biotechnology company based in San Francisco, founded in 2016, focused on bioprinting vascularized human tissues and organs for drug development, disease modeling, and transplantation. Its platform enables rapid, high-resolution printing of tissues and organoids, including lymph node models, to reproduce human immune responses. This capability supports antibody discovery, immunogenicity assessment, and tumor–immune studies, aiming to accelerate early-stage drug discovery and translational pharmacology while advancing the development of tissue and organ therapies.

Wild Earth is a technology-driven pet food company that develops plant-based, clean-protein diets for pets. It aims to provide healthier nutrition that is more humane and environmentally sustainable than conventional pet foods. Founded in 2017 and headquartered in Berkeley, California, Wild Earth emphasizes science-based formulations to meet pets' nutritional needs while reducing environmental impact.

SyntheX specializes in drug discovery using synthetic biology platforms. It identifies protein interaction modulators and enables functional protein degradation, focusing on unique mechanisms for cancer and rare disease treatments.

Simbe Robotics, Inc. is a San Francisco-based company established in 2014 that specializes in developing and manufacturing autonomous robotic solutions for the retail sector. Its flagship product, Tally, automates the labor-intensive process of shelf auditing by navigating store aisles to assess inventory levels. Tally identifies out-of-stock items, low stock items, misplaced products, and pricing discrepancies, providing valuable data to store staff. The robot operates safely alongside customers and employees during regular store hours, thereby enhancing operational efficiency and accuracy in retail environments.

BioLumen is a nutritional technology company that develops a patented dietary fiber technology platform that reduces the negative effect of a diet heavy in processed foods. BioLumen's technology is composed of insoluble dietary fiber matrix covered with a blend of food ingredients created from the latest drug delivery system research. The company's product, a nutraceutical, focuses on high risk individuals with prediabetes to help manage blood sugar levels, protect their liver from excess sugar and feed their gut microbiome, delivering health benefits. BioLumen was founded on 2018 and is headquartered in San Francisco, California.

Founded in 2020, Wild Energy is a California-based startup focused on innovative electric vehicle battery solutions.

Founded in 2020, Wild Energy is a California-based startup focused on innovative electric vehicle battery solutions.

ViaBot Inc. specializes in developing autonomous outdoor robots tailored for commercial maintenance tasks. Founded in 2016 and headquartered in Sunnyvale, California, the company offers multi-functional robots that address various outdoor responsibilities, including sweeping, lawn mowing, and security. Their RUNO robots utilize advanced vision technology to monitor and scan properties, such as recognizing vehicle license plates. ViaBot's autonomous solutions feature modular technology, round-the-clock monitoring, easy scheduling, and long operational runtimes, thus enabling businesses like shopping malls and sports arenas to efficiently manage their outdoor environments. The company's commitment to ongoing updates ensures their robots remain effective and adaptable to changing needs.

UPSIDE Foods, formerly known as Memphis Meats, is a cultivated meat company founded in 2015 and headquartered in Berkeley, California. The company specializes in producing real meat, poultry, and seafood directly from animal cells, eliminating the need to raise and slaughter animals. This innovative approach significantly reduces the resource consumption associated with traditional meat production, requiring less water, land, and energy. UPSIDE Foods aims to offer consumers clean, humane, and sustainable meat products, such as beef meatballs, chicken, and duck, all grown in controlled environments. The company is led by Dr. Uma Valeti, who is committed to transforming the food industry with healthier and environmentally friendly alternatives to conventional meat.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing innovative gene therapy treatments for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes advanced oral lipid nanoparticle technology to deliver mRNA and plasmid DNA directly to intestinal stem cells. This approach aims to address the root causes of gastrointestinal diseases, including Familial Adenomatous Polyposis (FAP), a hereditary condition that can lead to colorectal cancer and often necessitates invasive surgical interventions. DNALite's therapies seek to transform protein biologics into oral drugs, allowing for more effective and less invasive treatment options.

Windfall Bio is an innovative company based in San Mateo, California, that addresses climate change by transforming harmful methane emissions into organic fertilizer. Established in 2022, the company utilizes methane-eating microbes to capture methane from various sources, including agriculture, oil and gas, and waste management. This nature-based technology not only reduces the methane footprint of these industries but also improves their operational efficiency and profitability while minimizing the negative environmental impacts associated with synthetic fertilizers. By providing farmers and other producers with the means to convert methane into valuable soil nutrients, Windfall Bio fosters a sustainable agricultural future and contributes positively to environmental conservation. The company is backed by prominent venture capital firms, reflecting its potential to make a significant impact in the fight against climate change.

Qwasar Silicon Valley is a software engineering school and apprenticeship platform that trains backend software engineering, low-level programming, embedded engineering, and artificial intelligence and machine learning. It operates an experiential learning platform backed by automation and data to help students develop practical technical skills and pursue professional roles. The program collaborates with leading tech companies to provide real-world training and aims to expand diversity in the tech workforce.

Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on cultivating marine-animal cells to create sustainable fish and seafood alternatives, including bluefin tuna. Finless Foods aims to provide a variety of food options that cater to diverse tastes and dietary preferences while promoting responsible production practices. By offering accessible plant-based and cell-cultured seafood alternatives, the company seeks to contribute to better ocean health and foster a more sustainable future for food consumption.

Stämm Biotech is a San Francisco-based company specializing in advanced bioproduction systems designed to address the scaling challenges in the biotech industry. Founded in 2014, Stämm has developed an innovative biomanufacturing solution that integrates microfluidics, electroporation, and robotics, resulting in a compact, all-in-one Bioprocessor. This system has demonstrated productivity levels at least 70 times greater than traditional bioreactors, enabling clients to miniaturize bioreactors and optimize conditions more efficiently. Stämm's technology incorporates various sensors to monitor biological, physical, and chemical variations throughout the bioprocess, facilitating a streamlined approach to microbial growth and monoclonal cell line development. By transforming large-scale biotech operations into a more manageable micro-factory network, Stämm aims to unlock significant market potential in the coming years.

Founded in 2014, QuantumCyte develops an automated tissue dissection system that uses digital maps to isolate regions of interest containing informative biomarkers. This platform aims to improve cancer outcomes by enabling precise cellular data analysis for predicting drug efficacy.

Avisa Myko is a biotechnology company based in San Francisco, California. It specializes in the production of melanin, a natural pigment with applications in cosmetics, biomedicine, organic semiconductors, biosensors, and latex products. The company's patented technology enables large-scale production of soluble, affordable melanin, offering protection against ionizing radiation and contributing to better health and environmental sustainability.

Founded in 2021, Sóliome is a biotechnology company based in San Francisco, California. It specializes in developing protein-based sunscreens that are safe and effective, using molecules naturally produced by the human body to protect against harmful UV rays.

Founded in 2021, Sóliome is a biotechnology company based in San Francisco, California. It specializes in developing protein-based sunscreens that are safe and effective, using molecules naturally produced by the human body to protect against harmful UV rays.

Chronus Health develops a portable diagnostic device for delivering point-of-care lab results in minutes. Its device enables real-time diagnosis at the point-of-care, improving time to care and patient outcomes.

Labrador Systems, Inc. is a technology company based in Oak Park, California, that specializes in developing assistive robots aimed at improving the quality of life for individuals. Founded in 2017, the company focuses on creating practical applications of advanced robotics technology to address daily needs, particularly in the home health sector. By combining innovative hardware and software systems, Labrador Systems aims to enhance everyday living for its users through the deployment of personal robots designed to provide support and assistance.

Hydrostasis develops a hydration monitor system for athletes to reach and maintain peak performance. The wearable sensors measure each athlete's optimal hydration range based on body composition and provide preventive notifications before dehydration symptoms affect performance. Based in San Diego, California, Hydrostasis collaborates with device manufacturers in both consumer and clinical applications to enable hydration monitoring capabilities. The company delivers personalized information with device-agnostic and clinical-grade accuracy and uses cloud-based data storage to deliver real-time, actionable hydration insights, enabling athletes to track their hydration ranges and sustain optimal performance.

Circularis Biotechnologies, Inc. is a biotechnology company founded in 2014 and headquartered in Oakland, California. The company specializes in developing innovative methods to regulate gene expression, which enhances the production yields of biotherapeutics. Circularis offers a range of products, including RACRE Variant Libraries, hCMV Variant Library, Protein expression with CMV promoters, and T7 Variant Library. In addition, it provides various services such as RACRE Enhancement, RACRE Discovery, RACRE Technology Access Program, and Ribozyme Analysis of Cis-Regulatory Elements. Through its advanced technologies and services, Circularis aims to improve the efficiency and effectiveness of biotherapeutic production.

Founded in 2013, ZymoChem develops eco-friendly chemical production processes using engineered microbes. These processes convert renewable feedstocks like sugars into industrial chemicals, minimizing carbon loss and enabling cost-competitive bio-based manufacturing.

The EVERY Company, formerly known as Clara Foods, specializes in producing animal-free proteins for the food and beverage industry. Founded in 2014 and based in South San Francisco, California, the company utilizes advanced fermentation technology to create functional and nutritional proteins derived from microorganisms. Its product line includes baking ingredients, nutritional supplements, and egg white alternatives that are free from pathogens and suitable for various culinary applications, such as cakes and meringues. The EVERY Company aims to provide a sustainable, healthier, and kinder alternative to traditional animal agriculture by decoupling protein production from animals, thereby offering consumers healthy and affordable protein options without added sugars.

Founded in 2014, Lingrove specializes in manufacturing eco-friendly bio-composite materials. Utilizing a proprietary process, they produce high-performance natural fiber composites from plant-based fibers and resins, aiming to reduce deforestation and embodied carbon in industries such as commercial interiors, transportation, and construction.

Founded in 2018, New Culture is a food company based in San Francisco, California. It specializes in producing sustainable, animal-free cheese using microflora to create dairy proteins.

Founded in 2020, Prolific Machines is a San Francisco-based biotech company dedicated to revolutionizing cell production for a sustainable future. It combines advanced technologies to enable large-scale cell manufacturing, aiming to improve therapeutic protein production for biotechnology and pharmaceutical companies.

Sundial Foods develops plant-based meat alternatives designed to replicate the texture, appearance, and sensory experience of traditional meat using natural, plant-derived ingredients. The company aims to offer affordable, nutritious options for conscious consumers and to reduce meat consumption without relying on synthetic additives or heavily processed ingredients. Based in Berkeley, California, Sundial Foods was founded in 2019.

Particle Industries, Inc. is a provider of a comprehensive platform designed for the prototyping, scaling, and management of Internet of Things (IoT) products. The company offers a range of hardware development kits, including the Photon for Wi-Fi projects and the Electron for cellular-connected devices, along with various accessories like antennas and USB shields. Particle also delivers software tools such as Tinker, a mobile application for remote control, and Particle Build, a web-based development environment that allows users to write and deploy code easily. Its cloud platform facilitates secure interactions with connected devices through modern APIs, supporting developers in creating intelligent web services. With over 150,000 product builders across more than 170 countries, including notable clients like NASA and SpaceX, Particle has established itself as a key player in the IoT landscape. Founded in 2012 and headquartered in San Francisco, California, with an additional office in Shenzhen, China, the company has been recognized for its innovation and impact in the IoT sector.

Prothegen is a biotechnology company located in Palo Alto, California, focused on developing innovative medicines that precisely regulate cell death. The company has created a platform aimed at delivering therapies that can either inhibit or promote ferroptosis, a form of regulated cell death. By targeting this mechanism, Prothegen seeks to provide effective therapeutics that can prevent unwanted cell death, thereby improving treatment options for various diseases.

Prothegen is a biotechnology company located in Palo Alto, California, focused on developing innovative medicines that precisely regulate cell death. The company has created a platform aimed at delivering therapies that can either inhibit or promote ferroptosis, a form of regulated cell death. By targeting this mechanism, Prothegen seeks to provide effective therapeutics that can prevent unwanted cell death, thereby improving treatment options for various diseases.

California Cultured is a food company based in Davis, California, that specializes in creating sustainable, lab-grown cocoa and coffee through advanced cellular agriculture techniques. Founded in 2020, the company focuses on producing cocoa that is less bitter and requires less sugar, while also ensuring its products are healthier for consumers. By stimulating cocoa cell growth using common food ingredients, California Cultured aims to provide high-quality cocoa products that are free from the ethical issues traditionally associated with cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious and sustainable cocoa without the environmental and social drawbacks of conventional methods.

Founded in 2016, Abbot's Butcher produces high-quality, small-batch plant-based meat products. Their allergen-friendly range includes items like chopped chick'n, beef sausage, and chorizo, crafted from whole food ingredients.

Getaround, Inc. is an online marketplace specializing in peer-to-peer car sharing and local car rentals. Founded in 2009 and based in San Francisco, California, Getaround allows users to rent vehicles on-demand, ranging from economy cars to luxury models, by the hour or day. The platform facilitates a seamless experience through its patented Getaround Connect technology, which enables users to access cars without needing to meet the vehicle owner or handle physical keys. This innovative approach eliminates the traditional hassles of car rental, such as long lines and paperwork. Getaround operates in several major U.S. cities, including San Francisco, San Diego, Chicago, and Washington, D.C., providing a convenient and eco-friendly alternative to car ownership while allowing vehicle owners to earn extra income. The service also includes comprehensive insurance and 24/7 roadside assistance, ensuring a safe and enjoyable experience for users.

Perfect Day, Inc. is a pioneering company based in Emeryville, California, that specializes in producing animal-free dairy products. Founded in 2014, the company creates milk, cheese, yogurt, milk proteins, and ice cream that are nutritionally identical to traditional dairy but are made through a fermentation process using plant-based sugars. This innovative approach allows Perfect Day to deliver products that retain the taste, texture, and nutrition of conventional dairy while eliminating concerns related to food safety, environmental impact, and animal welfare. The company's commitment to sustainability and compassion results in nutrient-dense alternatives that are vegan, free from antibiotics, cholesterol, and lactose, catering to a growing market for healthier and more ethical food options.

Indee Labs develops hardware and platform technologies for gene delivery to immune cells, with the aim of enabling the rapid development and scalable manufacture of gene-modified cell therapies, including CAR-T cells. The company focuses on non-viral delivery methods to introduce small molecules, nucleic acids, proteins, and gene-editing complexes into immune cells, supporting biopharmaceutical research and manufacturing while maintaining high cell viability and function. Its technology has progressed with collaboration from national facilities and through participation in biotech incubators and accelerators. Indee Labs maintains an international footprint, with an office in Sydney and lab space in Berkeley, reflecting its cross-regional development and manufacturing focus.

Khepra is a company based in San Francisco, California, that specializes in converting plastics and agricultural waste into renewable fuels and chemicals. Utilizing proprietary technology, Khepra employs ultrasonic methods, including frictive heating, cavitation, and acoustic pressure, to break down waste streams without extraction, thus preserving their integrity. This innovative, electrified process leverages excess renewable electricity, particularly from solar and wind sources, during periods of energy curtailment. By transforming waste into valuable resources, Khepra aims to support industries in adopting clean energy solutions and contribute to a sustainable future.

Unspun, Inc. is a digital apparel company based in San Francisco, California, founded in 2015. It specializes in creating custom jeans tailored to individual consumers using advanced body scanning technology, fit algorithms, and additive manufacturing. The company aims to address environmental challenges by minimizing pattern-cutting waste and unsold inventory, thus contributing to a reduction in global carbon emissions. Unspun's innovative approach enables on-demand production of jeans in under ten minutes, utilizing localized manufacturing processes designed to be zero-waste. Its technology has gained recognition, including being named one of TIME's Best Inventions of 2019, and supports a B2B platform that facilitates digital customization for major apparel brands.

Founded in 2019, Karma Biotechnologies is a Los Angeles-based company dedicated to developing therapies for autoimmune diseases, allergies, and food sensitivities. It specializes in antigen-specific immunotherapies using lipid nanoparticle engineering.

Kegg is a company that specializes in women's health, focusing on fertility tracking and pelvic floor exercising. Established in 2017 and based in San Francisco, California, Kegg has developed an innovative device that combines these two aspects into a single, user-friendly product. The device effectively tracks changes in vaginal and cervical fluids, enabling users to identify their fertile window and predict ovulation up to seven days in advance. This capability significantly enhances the chances of natural conception by providing women with crucial data to support informed decisions regarding their reproductive health. By implementing advanced sensing technology, Kegg aims to improve diagnosis, monitoring, and treatment related to women's fertility.

Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on cultivating marine-animal cells to create sustainable fish and seafood alternatives, including bluefin tuna. Finless Foods aims to provide a variety of food options that cater to diverse tastes and dietary preferences while promoting responsible production practices. By offering accessible plant-based and cell-cultured seafood alternatives, the company seeks to contribute to better ocean health and foster a more sustainable future for food consumption.

Microgenesis is a biotechnology company focused on fertility and pregnancy health monitoring. It has developed a platform that provides a non-invasive fertility test and personalized nutritional supplementation aimed at restoring women's fertility potential. The company's innovative diagnostic approach detects subclinical inflammation that negatively impacts ovarian function and implantation, specifically targeting women who have experienced challenges, including multiple failed IVF attempts. Operating out of a CLIA lab in Oakland, Microgenesis offers its solutions through OB-GYNs and direct-to-consumer channels. Additionally, the platform addresses imbalances in vaginal and intestinal microbiota linked to infertility and offers dual testing for immunological issues related to the endometrium, equipping patients with effective treatment options for complex reproductive health cases.

Filtricine, Inc., founded in 2017 and based in Santa Clara, California, is a clinical-stage biotechnology company focused on developing innovative therapies for cancer treatment. The company's approach involves targeted nutrient deprivation, which identifies and exploits metabolic vulnerabilities specific to cancer cells. By depleting nutrients critical to cancer growth without using traditional drugs, Filtricine aims to provide effective treatments that minimize harm to healthy cells.

Founded in 2020, Advanced Microbubbles specializes in developing microbubble technology for targeted drug delivery. Utilizing ultrasound, the company's products temporarily open barriers like the blood-brain barrier to facilitate local drug entry, enhancing precision and reducing side effects.

Filtricine, Inc., founded in 2017 and based in Santa Clara, California, is a clinical-stage biotechnology company focused on developing innovative therapies for cancer treatment. The company's approach involves targeted nutrient deprivation, which identifies and exploits metabolic vulnerabilities specific to cancer cells. By depleting nutrients critical to cancer growth without using traditional drugs, Filtricine aims to provide effective treatments that minimize harm to healthy cells.

Prellis Biologics is a biotechnology company based in San Francisco, founded in 2016, focused on bioprinting vascularized human tissues and organs for drug development, disease modeling, and transplantation. Its platform enables rapid, high-resolution printing of tissues and organoids, including lymph node models, to reproduce human immune responses. This capability supports antibody discovery, immunogenicity assessment, and tumor–immune studies, aiming to accelerate early-stage drug discovery and translational pharmacology while advancing the development of tissue and organ therapies.

Founded in 2014, QuantumCyte develops an automated tissue dissection system that uses digital maps to isolate regions of interest containing informative biomarkers. This platform aims to improve cancer outcomes by enabling precise cellular data analysis for predicting drug efficacy.