SOSV, established in 1995 and headquartered in Princeton, New Jersey, is a global venture capital firm specializing in early-stage investments. It focuses on deep tech innovations in the health and environmental sectors, supporting founders with breakthrough technologies through its HAX and IndieBio startup development programs. SOSV provides resources, facilities, and lab equipment to accelerate product development and scale, with a track record of helping its portfolio companies secure subsequent funding rounds led by top-tier investors.
Particle provides hardware and software tools to help users prototype, scale, and manage IoT products. Particle is an IoT device platform that enables businesses to easily add the power of connectivity to any product. From hardware to connectivity to device management and cloud, Particle provides developers with tools to prototype IoT solutions quickly as well as a reliable and secure platform for enterprises to scale. Over 150,000 product builders in more than 170 countries and half of the Fortune 500 have deployed connected IoT devices powered by Particle. Listed as one of Fast Company’s Most Innovative Companies of 2015 and named as a major player to watch in the IoT Landscape in IDC Marketscape’s 2018 Vendor Assessment, Particle’s customers include NASA, SpaceX, consumer hot tub manufacturer Jacuzzi, and coffee-brewing pioneer Keurig. Venture backed by Root Ventures, Spark Capital, and Qualcomm Ventures. Particle is based in San Francisco, CA and Shenzhen, China. Particle was founded on 2012.
Prellis Biologics
Series C in 2025
Prellis Biologics, Inc. specializes in creating human tissues for drug development and the eventual production of human organs for transplantation. Founded in 2016 and based in San Francisco, California, the company employs advanced bioprinting technology to develop vascularized human tissues and organs, aiming to overcome the challenges associated with microvasculature. Its innovative products include TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X. Prellis Biologics also focuses on accurately replicating the human immune response through lymph node organoids, which can be utilized for various applications such as antibody discovery and immunogenicity assessment. By addressing critical issues in early-stage drug development and translational pharmacology, Prellis Biologics seeks to improve patient outcomes in healthcare.
Abbot's Butcher
Convertible Note in 2025
Abbot's Butcher, Inc. is a producer and marketer of plant-based meat products, established in 2016 and located in San Clemente, California. The company specializes in crafting gourmet, small-batch meat alternatives that are allergen-friendly and made from whole food ingredients. Its product line includes a variety of offerings such as chopped chick’n, beef sausage, chorizo, turkey burgers, herb-roasted chicken deli slices, Italian meatballs, and ground chicken and beef, all created using high-quality vegetables, herbs, and spices. Abbot's Butcher aims to provide consumers with accessible plant-based protein options that cater to diverse dietary preferences.
Tensorfield Agriculture
Convertible Note in 2025
Tensorfield Agriculture, founded in 2018 and based in San Jose, California, develops innovative agricultural machinery tailored for specialty row crops. The company focuses on creating robots equipped with computer vision technology that perform selective, non-invasive weeding without the use of herbicides, utilizing thermal micro-dosing techniques. This approach addresses the growing concern of herbicide resistance, allowing farmers to cultivate crops sustainably while ensuring the continued supply of safe, fresh food. Tensorfield Agriculture is supported by the HAX hardware accelerator and has received investment from the global venture capital firm SOSV, positioning it at the forefront of agricultural innovation in a post-herbicide landscape.
AlkaLi Labs
Convertible Note in 2024
AlkaLi Labs is a biotechnology research company based in San Francisco, California, established in 2023. The company focuses on developing biological solutions to harness domestic mineral resources. Currently operating in stealth mode, AlkaLi Labs aims to innovate in the field of biotechnology, leveraging biological processes to unlock valuable minerals.
Renewell
Seed Round in 2024
Renewell is a company based in Bakersfield, California, that transforms inactive oil and gas wells into gravity-based energy storage systems. This innovative process involves lowering a weight connected to a regenerative winch down a repurposed wellbore, allowing for the storage of energy during periods of low demand and the release of electricity back to the grid when demand increases. By utilizing existing oil and gas infrastructure, Renewell aims to create a flexible and cost-effective energy storage network while significantly reducing greenhouse gas emissions. The company's technology focuses on zero-self-discharge renewable energy storage, contributing to a more sustainable energy future.
OneSkin
Series A in 2024
OneSkin Inc. is a biotechnology company focused on developing innovative solutions to enhance skin health and combat aging. Founded by a team of PhDs and longevity scientists, the company has created a proprietary peptide, OS-01, which has been validated to reduce the biological age of skin by minimizing the accumulation of aged cells, enhancing cellular repair, and fortifying the epidermal barrier. OneSkin offers a flagship product, the OS-01 Topical Supplement, which is designed to be suitable for all skin types and is made from high-quality vegan ingredients. In addition to its product line, OneSkin specializes in creating advanced 3D human skin models for research and testing purposes, providing in vitro services to assess the efficacy and safety of cosmetic ingredients without the use of animals. Incorporated in 2016 and based in San Francisco, OneSkin is dedicated to advancing the understanding of skin biology and developing effective anti-aging solutions.
Laguna Bio
Seed Round in 2024
Laguna Bio is a biotechnology company based in Berkeley, California, founded in 2022. The company focuses on drug discovery, specifically developing a platform that activates and expands the innate immune system to combat cancer. Laguna Bio specializes in enhancing a specific type of T cell that targets solid tumors, aiming to improve the efficacy of bispecific antibody drugs. By increasing the immune response against these tumors, the company seeks to provide innovative solutions that may help patients survive cancer more effectively.
Sóliome
Seed Round in 2024
Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.
Tensorfield Agriculture
Seed Round in 2024
Tensorfield Agriculture, founded in 2018 and based in San Jose, California, develops innovative agricultural machinery tailored for specialty row crops. The company focuses on creating robots equipped with computer vision technology that perform selective, non-invasive weeding without the use of herbicides, utilizing thermal micro-dosing techniques. This approach addresses the growing concern of herbicide resistance, allowing farmers to cultivate crops sustainably while ensuring the continued supply of safe, fresh food. Tensorfield Agriculture is supported by the HAX hardware accelerator and has received investment from the global venture capital firm SOSV, positioning it at the forefront of agricultural innovation in a post-herbicide landscape.
unspun
Series B in 2024
Unspun, Inc., founded in 2015 and based in San Francisco, California, specializes in the development of a platform that creates customized jeans using advanced body scanning technology, fit algorithms, and additive manufacturing. The company aims to address environmental concerns by reducing global carbon emissions through automated and localized manufacturing processes. Unspun’s innovative approach not only eliminates pattern-cutting waste and unsold inventory but also allows for the production of jeans in under ten minutes in a zero-waste manner. Their technology is showcased through the unspun.io platform, which provides digital customization solutions for various apparel brands. With a mission to make fashion more sustainable, Unspun is positioned at the intersection of robotics and digital apparel, striving to transform the industry with its unique approach to on-demand manufacturing.
Wild
Seed Round in 2024
Situated in San Francisco, California, the company is presently functioning in stealth mode.
Kegg
Series A in 2024
Kegg is a fertility tracking device that combines the functions of monitoring vaginal fluid and facilitating pelvic floor exercises. Founded in 2017 and based in San Francisco, California, Kegg utilizes advanced sensing technology to detect changes in cervical fluid, thereby enabling women to identify their fertile window and ovulation up to seven days in advance. This innovative approach provides essential data that enhances the diagnosis, monitoring, and treatment of women's reproductive health, significantly increasing the chances of natural conception. By offering an intuitive and effective solution, Kegg empowers women with the information they need to make informed decisions regarding their fertility.
Particle
Convertible Note in 2024
Particle provides hardware and software tools to help users prototype, scale, and manage IoT products. Particle is an IoT device platform that enables businesses to easily add the power of connectivity to any product. From hardware to connectivity to device management and cloud, Particle provides developers with tools to prototype IoT solutions quickly as well as a reliable and secure platform for enterprises to scale. Over 150,000 product builders in more than 170 countries and half of the Fortune 500 have deployed connected IoT devices powered by Particle. Listed as one of Fast Company’s Most Innovative Companies of 2015 and named as a major player to watch in the IoT Landscape in IDC Marketscape’s 2018 Vendor Assessment, Particle’s customers include NASA, SpaceX, consumer hot tub manufacturer Jacuzzi, and coffee-brewing pioneer Keurig. Venture backed by Root Ventures, Spark Capital, and Qualcomm Ventures. Particle is based in San Francisco, CA and Shenzhen, China. Particle was founded on 2012.
Prolific Machines
Series B in 2024
Prolific Machines is a biotechnology company based in San Francisco, California, founded in 2020. It specializes in developing advanced cell technologies aimed at transforming the production of cells for sustainable applications, particularly in the cultivated meat industry. The company focuses on high-scale precision cell-differentiation techniques that enhance the efficiency, quality, reproducibility, and sustainability of cell production. Additionally, Prolific Machines is engaged in research and development efforts related to clean meat and cell therapies, utilizing innovative approaches to create better sustainable options. Through its work, the company aims to promote a healthier future for both humanity and the planet.
Lief Therapeutics
Seed Round in 2024
Lief Therapeutics is a medical device company focused on improving at-home care for individuals suffering from post-traumatic stress disorder, depression, and anxiety. The company has developed a discreet biosensing patch that measures heart rate and breathing patterns with medical accuracy. This wearable device, known as Lief, helps users manage their stress responses through biofeedback exercises, allowing them to monitor their emotions and behaviors in real-time. Additionally, the device provides clinicians with insights into patient progress, enabling in-session training and tracking of psychological assessments. Lief Therapeutics also offers the Lief Health Score application, which records thoughts, emotions, and sensations, facilitating the tracking of daily progress and personalized practice exercises. Founded in 2014 and based in San Francisco, California, the company sells its products online.
Finless Foods
Convertible Note in 2024
Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on growing marine-animal cells to create alternatives to traditional fish and seafood, including bluefin tuna. By offering a variety of responsibly produced food options, Finless Foods aims to cater to diverse tastes and dietary needs while promoting sustainability and better ocean health. The company's innovative approach provides consumers with healthy and accessible seafood alternatives, enabling them to maintain a balanced diet without compromising on flavor or variety.
California Organic Fertilizers
Series A in 2024
California Organic Fertilizers specializes in the production of certified organic fertilizers designed for agricultural use, particularly for organic farms. The company offers both liquid and dry fertilizers that are compliant with food safety standards and the National Organic Program. Sourced from local raw materials, these fertilizers provide high plant-available nitrogen, which is essential for promoting healthy crop growth. California Organic Fertilizers prioritizes the well-being of its workforce, communities, and the environment, ensuring that its products are suitable for organic farming operations as well as commercial landscape applications.
California Cultured
Series A in 2024
California Cultured is a food company based in Davis, California, that specializes in producing sustainable, lab-grown cocoa through advanced cellular agriculture techniques. Founded in 2020, the company aims to create cocoa that is less bitter and requires less sugar, enhancing the taste while promoting health benefits. By stimulating cocoa cells with common food ingredients, California Cultured ensures the growth of premium-quality cocoa without the ethical and environmental issues associated with traditional cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious cocoa products that are both sustainable and socially responsible.
Avisa Myko
Convertible Note in 2024
Avisa Myko Inc. is a biotechnology company based in San Francisco, California, specializing in the production of natural, water-soluble melanin. The company has developed a patented technology that allows for the large-scale and cost-effective manufacturing of melanin, which is used across various industries, including cosmetics, biomedicine, and environmental applications. Avisa Myko's melanin offers protection against ionizing radiation and is integrated into products such as latex, fabrics, laminated plastics, and glass. Additionally, the company is working on formulating a sunscreen that utilizes melanin as a natural ultraviolet blocker, eliminating the need for traditional chemical or mineral UV filters. By focusing on sustainable solutions, Avisa Myko aims to enhance human health and environmental safety through its innovative melanin products.
Zymochem
Series A in 2024
ZymoChem, Inc. is a biotechnology company based in Emeryville, California, founded in 2013. It specializes in the development of eco-friendly chemicals and bioprocesses using engineered microbes to convert renewable feedstocks, such as sugars, into industrial chemicals. The company’s bio-manufacturing platform aims to produce bio-based materials while minimizing carbon emissions during production, thereby supporting a carbon-efficient economy. By establishing cost-effective bioprocesses and novel biosynthetic pathways, ZymoChem enables clients to reduce production costs and enhance their competitiveness in the market. Through its innovative approach, the company contributes to sustainable manufacturing practices and the advancement of a real-zero economy.
Perfect Day
Series E in 2024
Perfect Day, Inc. is a pioneering company based in Emeryville, California, that specializes in producing animal-free dairy products. Founded in 2014, the company creates milk, cheese, yogurt, milk proteins, and ice cream that are nutritionally identical to traditional dairy but are made through a fermentation process using plant-based sugars. This innovative approach allows Perfect Day to deliver products that retain the taste, texture, and nutrition of conventional dairy while eliminating concerns related to food safety, environmental impact, and animal welfare. The company's commitment to sustainability and compassion results in nutrient-dense alternatives that are vegan, free from antibiotics, cholesterol, and lactose, catering to a growing market for healthier and more ethical food options.
Chronus Health
Convertible Note in 2024
Chronus Health, Inc. is a company that specializes in developing a portable diagnostic platform aimed at delivering rapid point-of-care lab results, specifically for complete blood count and comprehensive metabolic panel tests. Founded in 2017 and based in Mountain View, California, the company's innovative system utilizes microfluidics and semiconductor technology, combined with data analytics, to provide healthcare providers with real-time test results. This capability allows for immediate diagnosis at the point of care, enhancing the efficiency of treatment and significantly improving patient outcomes. By enabling doctors to obtain lab results in minutes, Chronus Health facilitates timely decision-making in clinical settings.
Tensorfield Agriculture
Convertible Note in 2023
Tensorfield Agriculture, founded in 2018 and based in San Jose, California, develops innovative agricultural machinery tailored for specialty row crops. The company focuses on creating robots equipped with computer vision technology that perform selective, non-invasive weeding without the use of herbicides, utilizing thermal micro-dosing techniques. This approach addresses the growing concern of herbicide resistance, allowing farmers to cultivate crops sustainably while ensuring the continued supply of safe, fresh food. Tensorfield Agriculture is supported by the HAX hardware accelerator and has received investment from the global venture capital firm SOSV, positioning it at the forefront of agricultural innovation in a post-herbicide landscape.
Lingrove
Series B in 2023
Lingrove, LLC is a manufacturer of bio-composite materials based in San Francisco, California, founded in 2014. The company specializes in high-performance natural fiber composites made from plant-based materials, utilizing a proprietary process to create products that mimic the appearance and properties of wood. Its flagship product, Ekoa, combines flax linen fibers with resin derived from industrial waste, and is primarily used in the production of musical instruments, as well as in the furniture, transportation, and construction industries. Lingrove aims to address the challenges posed by diminishing wood supplies and seeks to reduce deforestation and the carbon footprint associated with the built environment by offering sustainable, carbon-negative alternatives.
Prellis Biologics
Series C in 2023
Prellis Biologics, Inc. specializes in creating human tissues for drug development and the eventual production of human organs for transplantation. Founded in 2016 and based in San Francisco, California, the company employs advanced bioprinting technology to develop vascularized human tissues and organs, aiming to overcome the challenges associated with microvasculature. Its innovative products include TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X. Prellis Biologics also focuses on accurately replicating the human immune response through lymph node organoids, which can be utilized for various applications such as antibody discovery and immunogenicity assessment. By addressing critical issues in early-stage drug development and translational pharmacology, Prellis Biologics seeks to improve patient outcomes in healthcare.
ViaBot
Seed Round in 2023
ViaBot Inc. develops autonomous outdoor robots tailored for commercial properties, including sports arenas, shopping malls, and corporate buildings. Founded in 2016 and based in Sunnyvale, California, the company offers its RUNO robots, which are capable of performing various outdoor maintenance tasks such as sweeping, lawn mowing, and providing security. These robots utilize vision-based technology to enhance security features, including the ability to scan license plates. ViaBot's solutions are designed with modular technology that allows for easy scheduling and long runtimes, ensuring round-the-clock monitoring and constant updates. The company's innovative approach aims to simplify outdoor maintenance for businesses, making operations more efficient and effective.
Particle
Series C in 2023
Particle provides hardware and software tools to help users prototype, scale, and manage IoT products. Particle is an IoT device platform that enables businesses to easily add the power of connectivity to any product. From hardware to connectivity to device management and cloud, Particle provides developers with tools to prototype IoT solutions quickly as well as a reliable and secure platform for enterprises to scale. Over 150,000 product builders in more than 170 countries and half of the Fortune 500 have deployed connected IoT devices powered by Particle. Listed as one of Fast Company’s Most Innovative Companies of 2015 and named as a major player to watch in the IoT Landscape in IDC Marketscape’s 2018 Vendor Assessment, Particle’s customers include NASA, SpaceX, consumer hot tub manufacturer Jacuzzi, and coffee-brewing pioneer Keurig. Venture backed by Root Ventures, Spark Capital, and Qualcomm Ventures. Particle is based in San Francisco, CA and Shenzhen, China. Particle was founded on 2012.
QuantumCyte
Series A in 2023
QuantumCyte, Inc. is a technology platform company based in Sunnyvale, California, that specializes in cell analysis systems aimed at predicting drug efficacy and improving cancer treatment outcomes. Founded in 2014, QuantumCyte develops automated microdissection solutions for molecular pathology, utilizing digital tissue maps to isolate regions of interest that contain important biomarkers. By harnessing artificial intelligence in digital pathology, the company enables healthcare providers to perform precise single-cell analysis, enhancing the understanding of immune system and cancer biology.
Avisa Myko
Seed Round in 2023
Avisa Myko Inc. is a biotechnology company based in San Francisco, California, specializing in the production of natural, water-soluble melanin. The company has developed a patented technology that allows for the large-scale and cost-effective manufacturing of melanin, which is used across various industries, including cosmetics, biomedicine, and environmental applications. Avisa Myko's melanin offers protection against ionizing radiation and is integrated into products such as latex, fabrics, laminated plastics, and glass. Additionally, the company is working on formulating a sunscreen that utilizes melanin as a natural ultraviolet blocker, eliminating the need for traditional chemical or mineral UV filters. By focusing on sustainable solutions, Avisa Myko aims to enhance human health and environmental safety through its innovative melanin products.
Renewell
Seed Round in 2023
Renewell is a company based in Bakersfield, California, that transforms inactive oil and gas wells into gravity-based energy storage systems. This innovative process involves lowering a weight connected to a regenerative winch down a repurposed wellbore, allowing for the storage of energy during periods of low demand and the release of electricity back to the grid when demand increases. By utilizing existing oil and gas infrastructure, Renewell aims to create a flexible and cost-effective energy storage network while significantly reducing greenhouse gas emissions. The company's technology focuses on zero-self-discharge renewable energy storage, contributing to a more sustainable energy future.
unspun
Series A in 2023
Unspun, Inc., founded in 2015 and based in San Francisco, California, specializes in the development of a platform that creates customized jeans using advanced body scanning technology, fit algorithms, and additive manufacturing. The company aims to address environmental concerns by reducing global carbon emissions through automated and localized manufacturing processes. Unspun’s innovative approach not only eliminates pattern-cutting waste and unsold inventory but also allows for the production of jeans in under ten minutes in a zero-waste manner. Their technology is showcased through the unspun.io platform, which provides digital customization solutions for various apparel brands. With a mission to make fashion more sustainable, Unspun is positioned at the intersection of robotics and digital apparel, striving to transform the industry with its unique approach to on-demand manufacturing.
Karma Biotechnologies
Seed Round in 2023
Karma Biotechnologies, Inc. is a Los Angeles-based startup focused on developing therapies for autoimmune diseases, allergies, and food sensitivities. Founded in 2019, the company offers Xavines, a precision immunotherapy platform designed to address the critical need for antigen-specific therapies that target only the rogue immune cells responsible for these conditions. Unlike traditional treatments that rely on general immune suppression, Karma Biotechnologies aims to create tolerogenic immunotherapies that promote antigen-specific immune tolerance in vivo. By leveraging its expertise in immunology and lipid nanoparticle engineering, the company seeks to provide innovative solutions that enhance the treatment landscape for autoimmune diseases and related disorders.
California Cultured
Convertible Note in 2023
California Cultured is a food company based in Davis, California, that specializes in producing sustainable, lab-grown cocoa through advanced cellular agriculture techniques. Founded in 2020, the company aims to create cocoa that is less bitter and requires less sugar, enhancing the taste while promoting health benefits. By stimulating cocoa cells with common food ingredients, California Cultured ensures the growth of premium-quality cocoa without the ethical and environmental issues associated with traditional cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious cocoa products that are both sustainable and socially responsible.
AlkaLi Labs
Seed Round in 2023
AlkaLi Labs is a biotechnology research company based in San Francisco, California, established in 2023. The company focuses on developing biological solutions to harness domestic mineral resources. Currently operating in stealth mode, AlkaLi Labs aims to innovate in the field of biotechnology, leveraging biological processes to unlock valuable minerals.
Prime Roots
Series B in 2023
Prime Roots is a San Francisco-based company founded in 2017 that specializes in plant-based food products, particularly meat and seafood alternatives. Utilizing koji mycelium, the company creates vegetarian offerings such as salmon burgers that replicate the taste, texture, and nutrition of traditional meat and seafood. By leveraging natural koji proteins, Prime Roots aims to reduce the reliance on carbon-intensive animal agriculture, providing both meat-eaters and vegans with protein-rich and sustainable food options. In addition to its product offerings, the company also organizes food events for its members.
League of Play
Seed Round in 2023
League of Play is an interactive entertainment platform based in Los Angeles, California, that was founded in 2023. The platform focuses on creating competitions that unite top creators and athletes, aiming to bridge the gap between the online creator economy and live sports. By facilitating these competitions, League of Play generates interactive and viral content while offering substantial monetization opportunities through e-commerce, betting, and content licensing.
Geltor
Convertible Note in 2023
Geltor, Inc. is a biodesign company based in San Leandro, California, that specializes in producing bioactive, animal-free collagens and proteins for various applications in beauty, nutrition, and wellness. Established in 2015, Geltor offers innovative products such as Collume, which promotes skincare cellular regeneration and dermal synthesis, and HumaColl21, which enhances skin health by boosting collagen and elastin levels. Additionally, the company provides vegan collagen peptides and other novel proteins designed for functional food and nutraceutical formulations. Geltor's products are sustainably cultivated and clinically validated, allowing businesses to create effective, plant-based solutions that contribute to a more sustainable future.
Stämm Biotech
Series B in 2023
Stämm Biotech is a San Francisco-based company specializing in advanced bioproduction systems designed to address the scaling challenges in the biotech industry. Founded in 2014, Stämm has developed an innovative biomanufacturing solution that integrates microfluidics, electroporation, and robotics, resulting in a compact, all-in-one Bioprocessor. This system has demonstrated productivity levels at least 70 times greater than traditional bioreactors, enabling clients to miniaturize bioreactors and optimize conditions more efficiently. Stämm's technology incorporates various sensors to monitor biological, physical, and chemical variations throughout the bioprocess, facilitating a streamlined approach to microbial growth and monoclonal cell line development. By transforming large-scale biotech operations into a more manageable micro-factory network, Stämm aims to unlock significant market potential in the coming years.
Pulse Industrial
Venture Round in 2023
Pulse Industrial, founded in 2017 and based in California, specializes in developing advanced monitoring solutions for industrial plants, particularly focusing on steam systems. The company has created a smart steam trap monitoring device that employs artificial intelligence to detect steam leaks by analyzing vibration and acoustic behavior. This technology, known as QALM, enhances visibility into potential failures, alerting maintenance personnel through low power wide area communication. Additionally, Pulse Industrial is exploring thermal applications utilizing phase change materials, further expanding its innovative offerings in the industrial sector. By enabling remote monitoring of critical components like steam traps, the company aims to improve safety and reduce fuel consumption across various industrial processes.
Windfall Bio
Seed Round in 2023
Windfall Bio is a company focused on developing a sustainable technology that captures and transforms methane emissions into organic fertilizer, addressing significant environmental issues associated with methane and synthetic fertilizers. Founded in 2022 and based in San Mateo, California, Windfall Bio utilizes methane-eating microbes to convert methane from various sources, including agriculture, oil and gas, and waste management, into valuable soil nutrients. This innovative solution not only helps industries reduce their methane footprint but also enhances operational efficiency and profitability, benefiting the planet and consumers alike. The company is backed by prominent venture capital firms, demonstrating strong investor confidence in its mission to tackle climate change through nature-based agricultural technology.
DNALite Therapeutics
Convertible Note in 2023
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, DNALite utilizes innovative oral lipid nanoparticle technology to deliver mRNA and pDNA directly to intestinal stem cells. This approach targets the underlying causes of diseases such as Familial Adenomatous Polyposis, a hereditary form of colorectal cancer that often necessitates invasive surgeries in adolescents. By enabling the intestinal tract to secrete therapeutic proteins into the bloodstream, DNALite aims to transform conventional protein biologics into oral medications, potentially improving patient outcomes and accessibility to treatment.
Lief Therapeutics
Convertible Note in 2022
Lief Therapeutics is a medical device company focused on improving at-home care for individuals suffering from post-traumatic stress disorder, depression, and anxiety. The company has developed a discreet biosensing patch that measures heart rate and breathing patterns with medical accuracy. This wearable device, known as Lief, helps users manage their stress responses through biofeedback exercises, allowing them to monitor their emotions and behaviors in real-time. Additionally, the device provides clinicians with insights into patient progress, enabling in-session training and tracking of psychological assessments. Lief Therapeutics also offers the Lief Health Score application, which records thoughts, emotions, and sensations, facilitating the tracking of daily progress and personalized practice exercises. Founded in 2014 and based in San Francisco, California, the company sells its products online.
Tensorfield Agriculture
Convertible Note in 2022
Tensorfield Agriculture, founded in 2018 and based in San Jose, California, develops innovative agricultural machinery tailored for specialty row crops. The company focuses on creating robots equipped with computer vision technology that perform selective, non-invasive weeding without the use of herbicides, utilizing thermal micro-dosing techniques. This approach addresses the growing concern of herbicide resistance, allowing farmers to cultivate crops sustainably while ensuring the continued supply of safe, fresh food. Tensorfield Agriculture is supported by the HAX hardware accelerator and has received investment from the global venture capital firm SOSV, positioning it at the forefront of agricultural innovation in a post-herbicide landscape.
Particle
Series C in 2022
Particle provides hardware and software tools to help users prototype, scale, and manage IoT products. Particle is an IoT device platform that enables businesses to easily add the power of connectivity to any product. From hardware to connectivity to device management and cloud, Particle provides developers with tools to prototype IoT solutions quickly as well as a reliable and secure platform for enterprises to scale. Over 150,000 product builders in more than 170 countries and half of the Fortune 500 have deployed connected IoT devices powered by Particle. Listed as one of Fast Company’s Most Innovative Companies of 2015 and named as a major player to watch in the IoT Landscape in IDC Marketscape’s 2018 Vendor Assessment, Particle’s customers include NASA, SpaceX, consumer hot tub manufacturer Jacuzzi, and coffee-brewing pioneer Keurig. Venture backed by Root Ventures, Spark Capital, and Qualcomm Ventures. Particle is based in San Francisco, CA and Shenzhen, China. Particle was founded on 2012.
Prolific Machines
Convertible Note in 2022
Prolific Machines is a biotechnology company based in San Francisco, California, founded in 2020. It specializes in developing advanced cell technologies aimed at transforming the production of cells for sustainable applications, particularly in the cultivated meat industry. The company focuses on high-scale precision cell-differentiation techniques that enhance the efficiency, quality, reproducibility, and sustainability of cell production. Additionally, Prolific Machines is engaged in research and development efforts related to clean meat and cell therapies, utilizing innovative approaches to create better sustainable options. Through its work, the company aims to promote a healthier future for both humanity and the planet.
Renewell
Seed Round in 2022
Renewell is a company based in Bakersfield, California, that transforms inactive oil and gas wells into gravity-based energy storage systems. This innovative process involves lowering a weight connected to a regenerative winch down a repurposed wellbore, allowing for the storage of energy during periods of low demand and the release of electricity back to the grid when demand increases. By utilizing existing oil and gas infrastructure, Renewell aims to create a flexible and cost-effective energy storage network while significantly reducing greenhouse gas emissions. The company's technology focuses on zero-self-discharge renewable energy storage, contributing to a more sustainable energy future.
OneSkin
Venture Round in 2022
OneSkin Inc. is a biotechnology company focused on developing innovative solutions to enhance skin health and combat aging. Founded by a team of PhDs and longevity scientists, the company has created a proprietary peptide, OS-01, which has been validated to reduce the biological age of skin by minimizing the accumulation of aged cells, enhancing cellular repair, and fortifying the epidermal barrier. OneSkin offers a flagship product, the OS-01 Topical Supplement, which is designed to be suitable for all skin types and is made from high-quality vegan ingredients. In addition to its product line, OneSkin specializes in creating advanced 3D human skin models for research and testing purposes, providing in vitro services to assess the efficacy and safety of cosmetic ingredients without the use of animals. Incorporated in 2016 and based in San Francisco, OneSkin is dedicated to advancing the understanding of skin biology and developing effective anti-aging solutions.
Michroma
Seed Round in 2022
Michroma Corporation is a biotechnology company that specializes in producing natural thermostable colorants derived from filamentous fungi through a fermentation process. Founded in 2019 and based in both San Francisco, California, and Rosario, Argentina, Michroma aims to replace synthetic pigments and those sourced from animals and plants with sustainable, naturally produced alternatives. The company harnesses synthetic biology to develop proprietary fungal strains that generate high-performance ingredients in bioreactors. Currently, Michroma is prototyping its innovative pH-stable and heat-stable food colorants in collaboration with leading food and beverage and cosmetic companies. Additionally, the company is exploring the production of mycoprotein and other ingredients, making strides in the sustainable ingredients market.
Laguna Bio
Seed Round in 2022
Laguna Bio is a biotechnology company based in Berkeley, California, founded in 2022. The company focuses on drug discovery, specifically developing a platform that activates and expands the innate immune system to combat cancer. Laguna Bio specializes in enhancing a specific type of T cell that targets solid tumors, aiming to improve the efficacy of bispecific antibody drugs. By increasing the immune response against these tumors, the company seeks to provide innovative solutions that may help patients survive cancer more effectively.
Filtricine
Seed Round in 2022
Filtricine, Inc. is a clinical-stage biotechnology company based in Santa Clara, California, focused on developing therapeutic products for cancer treatment. Founded in 2017, the company specializes in a novel nutrient modulation platform that targets and depletes essential nutrients critical for cancer cell growth. By exploiting the metabolic vulnerabilities of cancer cells, Filtricine aims to halt the spread of cancer without relying on traditional drug substances. This approach allows healthcare professionals to utilize targeted nutrient deprivation therapy to address a broad spectrum of cancers effectively.
Renewell
Seed Round in 2022
Renewell is a company based in Bakersfield, California, that transforms inactive oil and gas wells into gravity-based energy storage systems. This innovative process involves lowering a weight connected to a regenerative winch down a repurposed wellbore, allowing for the storage of energy during periods of low demand and the release of electricity back to the grid when demand increases. By utilizing existing oil and gas infrastructure, Renewell aims to create a flexible and cost-effective energy storage network while significantly reducing greenhouse gas emissions. The company's technology focuses on zero-self-discharge renewable energy storage, contributing to a more sustainable energy future.
Melio
Seed Round in 2022
Melio is a healthcare company based in Santa Clara, California, specializing in blood testing technology aimed at detecting prevalent infections. The company has developed a comprehensive blood test platform that identifies common pathogens responsible for bloodstream infections. Utilizing a patented melting technique followed by detailed analysis, Melio's technology enables quick and accurate identification of blood-based pathogens. This innovation allows healthcare providers to deliver timely and targeted treatment, addressing the urgent need for effective therapies while also contributing to the fight against antibiotic resistance.
Prellis Biologics
Series C in 2022
Prellis Biologics, Inc. specializes in creating human tissues for drug development and the eventual production of human organs for transplantation. Founded in 2016 and based in San Francisco, California, the company employs advanced bioprinting technology to develop vascularized human tissues and organs, aiming to overcome the challenges associated with microvasculature. Its innovative products include TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X. Prellis Biologics also focuses on accurately replicating the human immune response through lymph node organoids, which can be utilized for various applications such as antibody discovery and immunogenicity assessment. By addressing critical issues in early-stage drug development and translational pharmacology, Prellis Biologics seeks to improve patient outcomes in healthcare.
Wild Earth
Venture Round in 2022
Wild Earth is a technology startup based in Berkeley, California, founded in 2017. The company specializes in developing sustainable protein pet foods for dogs and cats, focusing on creating healthier options that are also environmentally friendly and humane compared to traditional pet food products. By leveraging scientific advancements, Wild Earth aims to ensure that pets receive all their nutritional needs while promoting a more sustainable approach to pet food production.
SyntheX
Convertible Note in 2022
SyntheX, Inc. is a biotechnology company based in San Francisco, California, that specializes in drug discovery focused on therapeutic applications, particularly in oncology. Founded in 2016, SyntheX employs a proprietary screening platform that utilizes synthetic biology to expand the druggable proteome. This platform enables the identification of protein interaction modulators through empirical intracellular selection, allowing for the discovery of compounds that can disrupt specific protein-protein interactions or facilitate functional protein degradation. The company's development portfolio includes stabilized peptide therapeutics, such as STX101 and STX105, aimed at treating cancers that utilize homologous recombination for chemotherapy evasion. SyntheX's approach integrates advanced technologies and engineered circuits to create a robust internal pipeline targeting genetically validated therapeutic mechanisms, while also engaging in external discovery collaborations.
Simbe Robotics
Convertible Note in 2022
Simbe Robotics, Inc. is a technology company based in San Francisco, California, specializing in autonomous robotic solutions for the retail industry. Founded in 2014, the company has developed a robotic system named Tally, which autonomously navigates store aisles to conduct shelf audits. Tally captures real-time inventory data, identifying out-of-stock items, low stock levels, misplaced products, and pricing discrepancies. By automating these repetitive and labor-intensive tasks, Simbe Robotics enhances operational efficiency for retail staff, allowing them to focus on customer service and other critical aspects of store management. The robotic system operates safely during regular store hours, effectively integrating into the shopping environment without disrupting customers or employees.
BioLumen
Convertible Note in 2022
BioLumen is a nutritional technology company that develops a patented dietary fiber technology platform that reduces the negative effect of a diet heavy in processed foods. BioLumen's technology is composed of insoluble dietary fiber matrix covered with a blend of food ingredients created from the latest drug delivery system research. The company's product, a nutraceutical, focuses on high risk individuals with prediabetes to help manage blood sugar levels, protect their liver from excess sugar and feed their gut microbiome, delivering health benefits. BioLumen was founded on 2018 and is headquartered in San Francisco, California.
Wild.
Convertible Note in 2022
Wild is a stealth startup based in Santa Monica, California, focused on developing energy-efficient batteries for electric vehicles. Founded in 2020, the company is dedicated to innovating in the battery sector, aiming to enhance the performance and sustainability of electric vehicle technology. Operating in stealth mode, Wild is working on advanced solutions to meet the growing demand for efficient energy storage in the automotive industry.
Wild.
Seed Round in 2022
Wild is a stealth startup based in Santa Monica, California, focused on developing energy-efficient batteries for electric vehicles. Founded in 2020, the company is dedicated to innovating in the battery sector, aiming to enhance the performance and sustainability of electric vehicle technology. Operating in stealth mode, Wild is working on advanced solutions to meet the growing demand for efficient energy storage in the automotive industry.
ViaBot
Seed Round in 2022
ViaBot Inc. develops autonomous outdoor robots tailored for commercial properties, including sports arenas, shopping malls, and corporate buildings. Founded in 2016 and based in Sunnyvale, California, the company offers its RUNO robots, which are capable of performing various outdoor maintenance tasks such as sweeping, lawn mowing, and providing security. These robots utilize vision-based technology to enhance security features, including the ability to scan license plates. ViaBot's solutions are designed with modular technology that allows for easy scheduling and long runtimes, ensuring round-the-clock monitoring and constant updates. The company's innovative approach aims to simplify outdoor maintenance for businesses, making operations more efficient and effective.
UPSIDE Foods
Series C in 2022
UPSIDE Foods, formerly known as Memphis Meats, is a cultivated meat company founded in 2015 and headquartered in Berkeley, California. The company specializes in producing real meat, poultry, and seafood directly from animal cells, eliminating the need to raise and slaughter animals. This innovative approach significantly reduces the resource consumption associated with traditional meat production, requiring less water, land, and energy. UPSIDE Foods aims to offer consumers clean, humane, and sustainable meat products, such as beef meatballs, chicken, and duck, all grown in controlled environments. The company is led by Dr. Uma Valeti, who is committed to transforming the food industry with healthier and environmentally friendly alternatives to conventional meat.
DNALite Therapeutics
Venture Round in 2022
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, DNALite utilizes innovative oral lipid nanoparticle technology to deliver mRNA and pDNA directly to intestinal stem cells. This approach targets the underlying causes of diseases such as Familial Adenomatous Polyposis, a hereditary form of colorectal cancer that often necessitates invasive surgeries in adolescents. By enabling the intestinal tract to secrete therapeutic proteins into the bloodstream, DNALite aims to transform conventional protein biologics into oral medications, potentially improving patient outcomes and accessibility to treatment.
Windfall Bio
Seed Round in 2022
Windfall Bio is a company focused on developing a sustainable technology that captures and transforms methane emissions into organic fertilizer, addressing significant environmental issues associated with methane and synthetic fertilizers. Founded in 2022 and based in San Mateo, California, Windfall Bio utilizes methane-eating microbes to convert methane from various sources, including agriculture, oil and gas, and waste management, into valuable soil nutrients. This innovative solution not only helps industries reduce their methane footprint but also enhances operational efficiency and profitability, benefiting the planet and consumers alike. The company is backed by prominent venture capital firms, demonstrating strong investor confidence in its mission to tackle climate change through nature-based agricultural technology.
Qwasar Silicon Valley
Convertible Note in 2022
Qwasar Silicon Valley operates as a prominent software engineering school and apprenticeship provider in the United States, specializing in backend software engineering, artificial intelligence, and machine learning. The company employs a proprietary experiential learning platform that integrates automation and data analytics, serving over 6,000 users and experiencing consistent growth. Qwasar's training programs are designed to cultivate technical skills and foster a learning community, thereby empowering individuals to advance in their professional careers. Additionally, the company has formed strategic partnerships with leading technology firms to enhance workforce diversity within the tech industry.
Finless Foods
Series B in 2022
Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on growing marine-animal cells to create alternatives to traditional fish and seafood, including bluefin tuna. By offering a variety of responsibly produced food options, Finless Foods aims to cater to diverse tastes and dietary needs while promoting sustainability and better ocean health. The company's innovative approach provides consumers with healthy and accessible seafood alternatives, enabling them to maintain a balanced diet without compromising on flavor or variety.
Stämm Biotech
Series A in 2022
Stämm Biotech is a San Francisco-based company specializing in advanced bioproduction systems designed to address the scaling challenges in the biotech industry. Founded in 2014, Stämm has developed an innovative biomanufacturing solution that integrates microfluidics, electroporation, and robotics, resulting in a compact, all-in-one Bioprocessor. This system has demonstrated productivity levels at least 70 times greater than traditional bioreactors, enabling clients to miniaturize bioreactors and optimize conditions more efficiently. Stämm's technology incorporates various sensors to monitor biological, physical, and chemical variations throughout the bioprocess, facilitating a streamlined approach to microbial growth and monoclonal cell line development. By transforming large-scale biotech operations into a more manageable micro-factory network, Stämm aims to unlock significant market potential in the coming years.
QuantumCyte
Convertible Note in 2022
QuantumCyte, Inc. is a technology platform company based in Sunnyvale, California, that specializes in cell analysis systems aimed at predicting drug efficacy and improving cancer treatment outcomes. Founded in 2014, QuantumCyte develops automated microdissection solutions for molecular pathology, utilizing digital tissue maps to isolate regions of interest that contain important biomarkers. By harnessing artificial intelligence in digital pathology, the company enables healthcare providers to perform precise single-cell analysis, enhancing the understanding of immune system and cancer biology.
Avisa Myko
Convertible Note in 2022
Avisa Myko Inc. is a biotechnology company based in San Francisco, California, specializing in the production of natural, water-soluble melanin. The company has developed a patented technology that allows for the large-scale and cost-effective manufacturing of melanin, which is used across various industries, including cosmetics, biomedicine, and environmental applications. Avisa Myko's melanin offers protection against ionizing radiation and is integrated into products such as latex, fabrics, laminated plastics, and glass. Additionally, the company is working on formulating a sunscreen that utilizes melanin as a natural ultraviolet blocker, eliminating the need for traditional chemical or mineral UV filters. By focusing on sustainable solutions, Avisa Myko aims to enhance human health and environmental safety through its innovative melanin products.
Sóliome
Seed Round in 2022
Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.
Sóliome
Convertible Note in 2022
Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.
Chronus Health
Series A in 2022
Chronus Health, Inc. is a company that specializes in developing a portable diagnostic platform aimed at delivering rapid point-of-care lab results, specifically for complete blood count and comprehensive metabolic panel tests. Founded in 2017 and based in Mountain View, California, the company's innovative system utilizes microfluidics and semiconductor technology, combined with data analytics, to provide healthcare providers with real-time test results. This capability allows for immediate diagnosis at the point of care, enhancing the efficiency of treatment and significantly improving patient outcomes. By enabling doctors to obtain lab results in minutes, Chronus Health facilitates timely decision-making in clinical settings.
Labrador Systems
Seed Round in 2022
Labrador Systems, Inc. is a technology company based in Oak Park, California, focused on developing assistive robots to enhance daily living. Founded in 2017, the company aims to improve the quality of life for individuals by creating a new generation of personal robots that address everyday needs. By leveraging advanced robotics hardware and software, Labrador Systems designs practical applications to support home health and assist individuals in their daily activities.
Hydrostasis
Convertible Note in 2021
Hydrostasis is a company based in San Diego, California, that specializes in developing hydration monitoring systems tailored for athletes. Its technology includes wearable sensors that assess individual hydration needs based on body composition, providing personalized and clinical-grade accuracy. The system offers real-time notifications to alert athletes before dehydration affects their performance. In addition to serving athletes, Hydrostasis collaborates with device manufacturers for both consumer and clinical applications, enhancing hydration monitoring capabilities across various platforms. By leveraging scientific methodologies and cloud-based data storage, Hydrostasis aims to empower athletes to optimize their hydration levels, ultimately supporting their physical and mental performance.
Circularis Biotechnologies
Convertible Note in 2021
Circularis Biotechnologies, Inc. is a biotechnology company focused on developing innovative methods to regulate gene expression, aiming to enhance the production yields of biotherapeutics. Founded in 2014 and based in Oakland, California, the company offers a range of products and services, including RACRE Variant Libraries, hCMV Variant Library, Protein expression with CMV promoters, and T7 Variant Library. Additionally, Circularis provides services such as RACRE Enhancement, RACRE Discovery, RACRE Technology Access Program, and Ribozyme Analysis of Cis-Regulatory Elements. Through its technology, Circularis Biotechnologies seeks to advance the capabilities of biotherapeutic production in the industry.
Zymochem
Seed Round in 2021
ZymoChem, Inc. is a biotechnology company based in Emeryville, California, founded in 2013. It specializes in the development of eco-friendly chemicals and bioprocesses using engineered microbes to convert renewable feedstocks, such as sugars, into industrial chemicals. The company’s bio-manufacturing platform aims to produce bio-based materials while minimizing carbon emissions during production, thereby supporting a carbon-efficient economy. By establishing cost-effective bioprocesses and novel biosynthetic pathways, ZymoChem enables clients to reduce production costs and enhance their competitiveness in the market. Through its innovative approach, the company contributes to sustainable manufacturing practices and the advancement of a real-zero economy.
The EVERY Company
Series C in 2021
The EVERY Company, formerly known as Clara Foods, specializes in producing animal-free proteins for the food and beverage industry. Founded in 2014 and based in South San Francisco, California, the company utilizes advanced fermentation technology to create functional and nutritional proteins derived from microorganisms. Its product line includes baking ingredients, nutritional supplements, and egg white alternatives that are free from pathogens and suitable for various culinary applications, such as cakes and meringues. The EVERY Company aims to provide a sustainable, healthier, and kinder alternative to traditional animal agriculture by decoupling protein production from animals, thereby offering consumers healthy and affordable protein options without added sugars.
Lingrove
Series A in 2021
Lingrove, LLC is a manufacturer of bio-composite materials based in San Francisco, California, founded in 2014. The company specializes in high-performance natural fiber composites made from plant-based materials, utilizing a proprietary process to create products that mimic the appearance and properties of wood. Its flagship product, Ekoa, combines flax linen fibers with resin derived from industrial waste, and is primarily used in the production of musical instruments, as well as in the furniture, transportation, and construction industries. Lingrove aims to address the challenges posed by diminishing wood supplies and seeks to reduce deforestation and the carbon footprint associated with the built environment by offering sustainable, carbon-negative alternatives.
New Culture
Series A in 2021
New Culture is a food and beverage company based in San Francisco, California, founded in 2018. The company specializes in producing animal-free cheese using innovative methods that involve microflora to create dairy proteins. By focusing on sustainable and ethical practices, New Culture aims to revolutionize the cheese-making process, offering a variety of delicious and healthy cheese alternatives. Their products are designed to reduce dependency on animal agriculture while providing consumers with access to nutritious dairy-like options.
Prolific Machines
Series A in 2021
Prolific Machines is a biotechnology company based in San Francisco, California, founded in 2020. It specializes in developing advanced cell technologies aimed at transforming the production of cells for sustainable applications, particularly in the cultivated meat industry. The company focuses on high-scale precision cell-differentiation techniques that enhance the efficiency, quality, reproducibility, and sustainability of cell production. Additionally, Prolific Machines is engaged in research and development efforts related to clean meat and cell therapies, utilizing innovative approaches to create better sustainable options. Through its work, the company aims to promote a healthier future for both humanity and the planet.
Sundial Foods
Seed Round in 2021
Sundial Foods, founded in 2019 and headquartered in Berkeley, California, specializes in creating plant-based meat alternatives aimed at environmentally conscious consumers. The company employs a macro and microstructural engineering approach to develop products that closely mimic the look, texture, and taste of traditional meat, all while ensuring affordability and nutritional value. By utilizing familiar ingredients and straightforward production processes, Sundial Foods strives to make plant-based meats accessible to a wider audience. The company's mission is to encourage a shift towards sustainable eating habits, thereby reducing meat consumption and its associated environmental impacts.
Particle
Series C in 2021
Particle provides hardware and software tools to help users prototype, scale, and manage IoT products. Particle is an IoT device platform that enables businesses to easily add the power of connectivity to any product. From hardware to connectivity to device management and cloud, Particle provides developers with tools to prototype IoT solutions quickly as well as a reliable and secure platform for enterprises to scale. Over 150,000 product builders in more than 170 countries and half of the Fortune 500 have deployed connected IoT devices powered by Particle. Listed as one of Fast Company’s Most Innovative Companies of 2015 and named as a major player to watch in the IoT Landscape in IDC Marketscape’s 2018 Vendor Assessment, Particle’s customers include NASA, SpaceX, consumer hot tub manufacturer Jacuzzi, and coffee-brewing pioneer Keurig. Venture backed by Root Ventures, Spark Capital, and Qualcomm Ventures. Particle is based in San Francisco, CA and Shenzhen, China. Particle was founded on 2012.
Prothegen
Seed Round in 2021
Prothegen is a biotechnology company located in Palo Alto, California, focused on developing innovative medicines that precisely regulate cell death. The company has created a platform aimed at delivering therapies that can inhibit or promote ferroptosis, a form of regulated cell death. By targeting this process, Prothegen seeks to provide effective therapeutic options for patients, enhancing the treatment of conditions associated with uncontrolled cell death.
Prothegen
Convertible Note in 2021
Prothegen is a biotechnology company located in Palo Alto, California, focused on developing innovative medicines that precisely regulate cell death. The company has created a platform aimed at delivering therapies that can inhibit or promote ferroptosis, a form of regulated cell death. By targeting this process, Prothegen seeks to provide effective therapeutic options for patients, enhancing the treatment of conditions associated with uncontrolled cell death.
California Cultured
Seed Round in 2021
California Cultured is a food company based in Davis, California, that specializes in producing sustainable, lab-grown cocoa through advanced cellular agriculture techniques. Founded in 2020, the company aims to create cocoa that is less bitter and requires less sugar, enhancing the taste while promoting health benefits. By stimulating cocoa cells with common food ingredients, California Cultured ensures the growth of premium-quality cocoa without the ethical and environmental issues associated with traditional cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious cocoa products that are both sustainable and socially responsible.
Abbot's Butcher
Series A in 2021
Abbot's Butcher, Inc. is a producer and marketer of plant-based meat products, established in 2016 and located in San Clemente, California. The company specializes in crafting gourmet, small-batch meat alternatives that are allergen-friendly and made from whole food ingredients. Its product line includes a variety of offerings such as chopped chick’n, beef sausage, chorizo, turkey burgers, herb-roasted chicken deli slices, Italian meatballs, and ground chicken and beef, all created using high-quality vegetables, herbs, and spices. Abbot's Butcher aims to provide consumers with accessible plant-based protein options that cater to diverse dietary preferences.
Getaround
Convertible Note in 2021
Getaround, Inc. is an online marketplace specializing in peer-to-peer car sharing and local car rentals. Founded in 2009 and based in San Francisco, California, Getaround allows users to rent vehicles on-demand, ranging from economy cars to luxury models, by the hour or day. The platform facilitates a seamless experience through its patented Getaround Connect technology, which enables users to access cars without needing to meet the vehicle owner or handle physical keys. This innovative approach eliminates the traditional hassles of car rental, such as long lines and paperwork. Getaround operates in several major U.S. cities, including San Francisco, San Diego, Chicago, and Washington, D.C., providing a convenient and eco-friendly alternative to car ownership while allowing vehicle owners to earn extra income. The service also includes comprehensive insurance and 24/7 roadside assistance, ensuring a safe and enjoyable experience for users.
Perfect Day
Series D in 2021
Perfect Day, Inc. is a pioneering company based in Emeryville, California, that specializes in producing animal-free dairy products. Founded in 2014, the company creates milk, cheese, yogurt, milk proteins, and ice cream that are nutritionally identical to traditional dairy but are made through a fermentation process using plant-based sugars. This innovative approach allows Perfect Day to deliver products that retain the taste, texture, and nutrition of conventional dairy while eliminating concerns related to food safety, environmental impact, and animal welfare. The company's commitment to sustainability and compassion results in nutrient-dense alternatives that are vegan, free from antibiotics, cholesterol, and lactose, catering to a growing market for healthier and more ethical food options.
Indee Labs
Convertible Note in 2021
Indee Labs specializes in developing innovative hardware for gene delivery, focusing on a non-viral intracellular delivery system. This technology facilitates the efficient development and scalable manufacture of gene-modified cell therapies, including chimeric antigen receptor T cells. By employing microfluidic vortex shedding, the system enables the gentle delivery of constructs such as nucleic acids, proteins, and gene-editing complexes to a variety of cell types, ensuring maximum recovery of viable, modified cells with minimal disruption. Indee Labs collaborates with the Australian National Fabrication Facility and has established its presence with offices in Sydney and lab space at Bonneville Labs in Berkeley. The company is recognized for its contributions to the field, having affiliations with NSW Health, IndieBio, Y Combinator, and MBC Biolabs.
Khepra
Seed Round in 2021
Khepra is a company based in San Francisco, California, that focuses on transforming plastics and agricultural waste into renewable fuels using innovative technology. The company employs a proprietary process that combines ultrasonic technology, frictive heating, cavitation, and acoustic pressure to efficiently break down waste streams. This method utilizes excess renewable electricity generated from solar and wind sources, particularly during times of low energy generation or curtailment. By converting waste into drop-in fuels and renewable chemicals without extraction, Khepra aims to support industries in their transition towards cleaner energy solutions and promote sustainability.
unspun
Series A in 2021
Unspun, Inc., founded in 2015 and based in San Francisco, California, specializes in the development of a platform that creates customized jeans using advanced body scanning technology, fit algorithms, and additive manufacturing. The company aims to address environmental concerns by reducing global carbon emissions through automated and localized manufacturing processes. Unspun’s innovative approach not only eliminates pattern-cutting waste and unsold inventory but also allows for the production of jeans in under ten minutes in a zero-waste manner. Their technology is showcased through the unspun.io platform, which provides digital customization solutions for various apparel brands. With a mission to make fashion more sustainable, Unspun is positioned at the intersection of robotics and digital apparel, striving to transform the industry with its unique approach to on-demand manufacturing.
Karma Biotechnologies
Seed Round in 2021
Karma Biotechnologies, Inc. is a Los Angeles-based startup focused on developing therapies for autoimmune diseases, allergies, and food sensitivities. Founded in 2019, the company offers Xavines, a precision immunotherapy platform designed to address the critical need for antigen-specific therapies that target only the rogue immune cells responsible for these conditions. Unlike traditional treatments that rely on general immune suppression, Karma Biotechnologies aims to create tolerogenic immunotherapies that promote antigen-specific immune tolerance in vivo. By leveraging its expertise in immunology and lipid nanoparticle engineering, the company seeks to provide innovative solutions that enhance the treatment landscape for autoimmune diseases and related disorders.
Kegg
Seed Round in 2021
Kegg is a fertility tracking device that combines the functions of monitoring vaginal fluid and facilitating pelvic floor exercises. Founded in 2017 and based in San Francisco, California, Kegg utilizes advanced sensing technology to detect changes in cervical fluid, thereby enabling women to identify their fertile window and ovulation up to seven days in advance. This innovative approach provides essential data that enhances the diagnosis, monitoring, and treatment of women's reproductive health, significantly increasing the chances of natural conception. By offering an intuitive and effective solution, Kegg empowers women with the information they need to make informed decisions regarding their fertility.
Finless Foods
Convertible Note in 2021
Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on growing marine-animal cells to create alternatives to traditional fish and seafood, including bluefin tuna. By offering a variety of responsibly produced food options, Finless Foods aims to cater to diverse tastes and dietary needs while promoting sustainability and better ocean health. The company's innovative approach provides consumers with healthy and accessible seafood alternatives, enabling them to maintain a balanced diet without compromising on flavor or variety.
Microgenesis
Convertible Note in 2021
Microgenesis is a biotechnology company focused on improving fertility and pregnancy health through innovative diagnostic and treatment solutions. It offers a non-invasive fertility test that identifies subclinical inflammation affecting ovarian function and implantation, particularly beneficial for women who have experienced multiple IVF failures. The company's personalized nutritional supplementation aims to restore fertility potential in women, utilizing all-natural and drug-free methods. Operating out of a CLIA-certified lab in Oakland, Microgenesis is expanding its services to obstetricians and gynecologists, as well as direct-to-consumer markets. In addition to its fertility test, the company provides tools to analyze microbiota imbalances linked to infertility and immunological issues, thus addressing complex reproductive health cases comprehensively.
Advanced Microbubbles
Convertible Note in 2021
Advanced Microbubbles Inc specializes in developing microbubbles as ultrasound contrast agents for targeted drug delivery, particularly in overcoming significant biological barriers like the blood-brain barrier and tumor endothelium. Founded in 2020 and based in Newark, California, the company offers a range of products including size-isolated microbubbles, polydisperse microbubbles, and biotin- or streptavidin-tagged variants. These microbubbles are agitated with ultrasound at the tumor site, facilitating the local delivery of drugs by temporarily opening barriers that typically hinder treatment. By enabling more effective drug delivery, Advanced Microbubbles aims to reduce side effects and improve survival outcomes for patients with various neurological conditions and cancer.
Filtricine
Seed Round in 2021
Filtricine, Inc. is a clinical-stage biotechnology company based in Santa Clara, California, focused on developing therapeutic products for cancer treatment. Founded in 2017, the company specializes in a novel nutrient modulation platform that targets and depletes essential nutrients critical for cancer cell growth. By exploiting the metabolic vulnerabilities of cancer cells, Filtricine aims to halt the spread of cancer without relying on traditional drug substances. This approach allows healthcare professionals to utilize targeted nutrient deprivation therapy to address a broad spectrum of cancers effectively.
Filtricine
Seed Round in 2021
Filtricine, Inc. is a clinical-stage biotechnology company based in Santa Clara, California, focused on developing therapeutic products for cancer treatment. Founded in 2017, the company specializes in a novel nutrient modulation platform that targets and depletes essential nutrients critical for cancer cell growth. By exploiting the metabolic vulnerabilities of cancer cells, Filtricine aims to halt the spread of cancer without relying on traditional drug substances. This approach allows healthcare professionals to utilize targeted nutrient deprivation therapy to address a broad spectrum of cancers effectively.
Prellis Biologics
Series B in 2021
Prellis Biologics, Inc. specializes in creating human tissues for drug development and the eventual production of human organs for transplantation. Founded in 2016 and based in San Francisco, California, the company employs advanced bioprinting technology to develop vascularized human tissues and organs, aiming to overcome the challenges associated with microvasculature. Its innovative products include TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X. Prellis Biologics also focuses on accurately replicating the human immune response through lymph node organoids, which can be utilized for various applications such as antibody discovery and immunogenicity assessment. By addressing critical issues in early-stage drug development and translational pharmacology, Prellis Biologics seeks to improve patient outcomes in healthcare.
QuantumCyte
Convertible Note in 2021
QuantumCyte, Inc. is a technology platform company based in Sunnyvale, California, that specializes in cell analysis systems aimed at predicting drug efficacy and improving cancer treatment outcomes. Founded in 2014, QuantumCyte develops automated microdissection solutions for molecular pathology, utilizing digital tissue maps to isolate regions of interest that contain important biomarkers. By harnessing artificial intelligence in digital pathology, the company enables healthcare providers to perform precise single-cell analysis, enhancing the understanding of immune system and cancer biology.
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