SOSV

Brightwater Tools, headquartered in Vermont, is a woman-led startup specializing in sustainable sanitation solutions. The company has developed a unique building-scale wastewater nutrient recovery system that transforms high-strength wastewater into natural, nutrient-rich fertilizer. This process not only reduces harmful algal blooms in waterways but also promotes a circular economy by recycling nutrients. The system comprises three proprietary pieces of equipment, each facilitating key wastewater processes and available for individual or collective purchase. Brightwater Tools aims to become a significant equipment provider in this sector, with a strong customer base expected upon completion of its prototype and beta testing.

Gatehouse Bio is a biotechnology company based in Waltham, Massachusetts, focused on the accelerated development of therapies utilizing small ribonucleic acid (RNA) and advanced bioinformatics. Founded in 2016, the company has developed a platform that employs artificial intelligence to identify error-free RNA biomarkers and discover disease-associated mutations. This platform enables precise classification of patient samples, which aids in the design of targeted therapeutics aimed at addressing various diseases, particularly in areas characterized by known heterogeneity such as fibrosis, inflammation, and neurodegeneration. By analyzing small RNA genes, Gatehouse Bio aims to unlock the potential for innovative treatments that could significantly enhance patient outcomes.

Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.

Gatehouse Bio is a biotechnology company based in Waltham, Massachusetts, focused on the accelerated development of therapies utilizing small ribonucleic acid (RNA) and advanced bioinformatics. Founded in 2016, the company has developed a platform that employs artificial intelligence to identify error-free RNA biomarkers and discover disease-associated mutations. This platform enables precise classification of patient samples, which aids in the design of targeted therapeutics aimed at addressing various diseases, particularly in areas characterized by known heterogeneity such as fibrosis, inflammation, and neurodegeneration. By analyzing small RNA genes, Gatehouse Bio aims to unlock the potential for innovative treatments that could significantly enhance patient outcomes.

Pear Bio is a biotechnology company based in Boston and London that focuses on developing precision medicine therapeutics for challenging cancer cases. By analyzing tumor biopsies and blood samples from patients, the company utilizes multi-omics approaches to identify new therapeutic targets. Their proprietary immune-microtumor system allows them to test the effectiveness of drug candidates directly on patient tumor samples. Pear Bio's innovative technology includes a specialized hydrogel that cultivates tumors outside the human body, effectively simulating drug resistance and streamlining the treatment selection process. This enables the identification of the most effective therapies for individual patients, thereby reducing the reliance on trial-and-error methods in cancer treatment.

Pear Bio is a biotechnology company based in Boston and London that focuses on developing precision medicine therapeutics for challenging cancer cases. By analyzing tumor biopsies and blood samples from patients, the company utilizes multi-omics approaches to identify new therapeutic targets. Their proprietary immune-microtumor system allows them to test the effectiveness of drug candidates directly on patient tumor samples. Pear Bio's innovative technology includes a specialized hydrogel that cultivates tumors outside the human body, effectively simulating drug resistance and streamlining the treatment selection process. This enables the identification of the most effective therapies for individual patients, thereby reducing the reliance on trial-and-error methods in cancer treatment.

BioROSA Technologies Inc. is a Belmont, Massachusetts-based company focused on developing blood tests for Autism Spectrum Disorders (ASD). Founded in 2018, the company aims to establish a biologically-based standard of care for ASD through innovative diagnostic tools. These tools enable clinicians to identify individuals at risk for ASD by utilizing blood-based biomarkers and advanced machine learning techniques. BioROSA’s platform not only enhances early detection and diagnosis but also supports therapeutic developments by facilitating patient stratification and assessing pharmacodynamics in clinical trials. This comprehensive approach equips healthcare professionals with the necessary resources to improve patient outcomes through timely intervention.

Harmony is a biotechnology startup that creates human breast milk protein-based infant nutrition designed to help human babies thrive. It is the world’s first dairy-free, allergen-free and environmentally friendly infant nutrition. Harmony Baby Nutrition was established in 2018 and is based in Boston, MA.

Gatehouse Bio is a biotechnology company based in Waltham, Massachusetts, focused on the accelerated development of therapies utilizing small ribonucleic acid (RNA) and advanced bioinformatics. Founded in 2016, the company has developed a platform that employs artificial intelligence to identify error-free RNA biomarkers and discover disease-associated mutations. This platform enables precise classification of patient samples, which aids in the design of targeted therapeutics aimed at addressing various diseases, particularly in areas characterized by known heterogeneity such as fibrosis, inflammation, and neurodegeneration. By analyzing small RNA genes, Gatehouse Bio aims to unlock the potential for innovative treatments that could significantly enhance patient outcomes.

Prospective Research, Inc. is a biotechnology company based in Beverly, Massachusetts, focused on developing innovative solutions for the aquaculture industry and antibiotic discovery. Established in 2015, the company utilizes its advanced technology platforms, including MicrobeMiner and GeneMiner, to access untapped antibiotics from soil-dwelling microbes. By employing microbial signaling molecules, Prospective Research creates feed incorporated preventative disease management solutions that eliminate the need for traditional antibiotics and medicated feed. Their approach involves modulating bacterial behavior and introducing trillions of beneficial bacteria into the microbiomes of farmed species such as fin-fish, shrimp, and shellfish. This technology enables the selective activation of genes that produce bio-active therapeutics, offering protection against various pathogens while enhancing the health of aquaculture species.

Gatehouse Bio is a biotechnology company based in Waltham, Massachusetts, focused on the accelerated development of therapies utilizing small ribonucleic acid (RNA) and advanced bioinformatics. Founded in 2016, the company has developed a platform that employs artificial intelligence to identify error-free RNA biomarkers and discover disease-associated mutations. This platform enables precise classification of patient samples, which aids in the design of targeted therapeutics aimed at addressing various diseases, particularly in areas characterized by known heterogeneity such as fibrosis, inflammation, and neurodegeneration. By analyzing small RNA genes, Gatehouse Bio aims to unlock the potential for innovative treatments that could significantly enhance patient outcomes.

Cellens is a medical device company based in Medford, Massachusetts, that specializes in noninvasive cancer screening, particularly for bladder cancer. Founded in 2019 as a spinoff from Tufts University, the company has developed a cell surface scanning platform that utilizes atomic force microscopy imaging and machine learning. This innovative platform analyzes physio-biomarkers on cell surfaces obtained from urine samples, generating a diagnostics score for bladder cancer. By providing oncologists and urologists with a reliable and less invasive alternative to traditional diagnostic methods, Cellens aims to enhance patient outcomes and reduce the need for costly and invasive procedures.

Cellens is a medical device company based in Medford, Massachusetts, that specializes in noninvasive cancer screening, particularly for bladder cancer. Founded in 2019 as a spinoff from Tufts University, the company has developed a cell surface scanning platform that utilizes atomic force microscopy imaging and machine learning. This innovative platform analyzes physio-biomarkers on cell surfaces obtained from urine samples, generating a diagnostics score for bladder cancer. By providing oncologists and urologists with a reliable and less invasive alternative to traditional diagnostic methods, Cellens aims to enhance patient outcomes and reduce the need for costly and invasive procedures.

Gatehouse Bio is a biotechnology company based in Waltham, Massachusetts, focused on the accelerated development of therapies utilizing small ribonucleic acid (RNA) and advanced bioinformatics. Founded in 2016, the company has developed a platform that employs artificial intelligence to identify error-free RNA biomarkers and discover disease-associated mutations. This platform enables precise classification of patient samples, which aids in the design of targeted therapeutics aimed at addressing various diseases, particularly in areas characterized by known heterogeneity such as fibrosis, inflammation, and neurodegeneration. By analyzing small RNA genes, Gatehouse Bio aims to unlock the potential for innovative treatments that could significantly enhance patient outcomes.

Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.

Catalog Technologies Inc. specializes in a DNA-based platform that revolutionizes digital data storage and computation. Founded in 2016 and headquartered in Boston, Massachusetts, the company provides a method for encoding digital information into DNA, making it a viable and cost-effective solution for long-term data archiving. By leveraging advanced synthetic biology technologies, Catalog aims to transform how information is stored, allowing customers to utilize DNA molecules as a primary medium for digital records. This innovative approach positions Catalog at the forefront of next-generation data storage solutions.

Pear Bio is a biotechnology company based in Boston and London that focuses on developing precision medicine therapeutics for challenging cancer cases. By analyzing tumor biopsies and blood samples from patients, the company utilizes multi-omics approaches to identify new therapeutic targets. Their proprietary immune-microtumor system allows them to test the effectiveness of drug candidates directly on patient tumor samples. Pear Bio's innovative technology includes a specialized hydrogel that cultivates tumors outside the human body, effectively simulating drug resistance and streamlining the treatment selection process. This enables the identification of the most effective therapies for individual patients, thereby reducing the reliance on trial-and-error methods in cancer treatment.

BioROSA Technologies Inc. is a Belmont, Massachusetts-based company focused on developing blood tests for Autism Spectrum Disorders (ASD). Founded in 2018, the company aims to establish a biologically-based standard of care for ASD through innovative diagnostic tools. These tools enable clinicians to identify individuals at risk for ASD by utilizing blood-based biomarkers and advanced machine learning techniques. BioROSA’s platform not only enhances early detection and diagnosis but also supports therapeutic developments by facilitating patient stratification and assessing pharmacodynamics in clinical trials. This comprehensive approach equips healthcare professionals with the necessary resources to improve patient outcomes through timely intervention.

Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.

Gatehouse Bio is a biotechnology company based in Waltham, Massachusetts, focused on the accelerated development of therapies utilizing small ribonucleic acid (RNA) and advanced bioinformatics. Founded in 2016, the company has developed a platform that employs artificial intelligence to identify error-free RNA biomarkers and discover disease-associated mutations. This platform enables precise classification of patient samples, which aids in the design of targeted therapeutics aimed at addressing various diseases, particularly in areas characterized by known heterogeneity such as fibrosis, inflammation, and neurodegeneration. By analyzing small RNA genes, Gatehouse Bio aims to unlock the potential for innovative treatments that could significantly enhance patient outcomes.

Harmony is a biotechnology startup that creates human breast milk protein-based infant nutrition designed to help human babies thrive. It is the world’s first dairy-free, allergen-free and environmentally friendly infant nutrition. Harmony Baby Nutrition was established in 2018 and is based in Boston, MA.

Gatehouse Bio is a biotechnology company based in Waltham, Massachusetts, focused on the accelerated development of therapies utilizing small ribonucleic acid (RNA) and advanced bioinformatics. Founded in 2016, the company has developed a platform that employs artificial intelligence to identify error-free RNA biomarkers and discover disease-associated mutations. This platform enables precise classification of patient samples, which aids in the design of targeted therapeutics aimed at addressing various diseases, particularly in areas characterized by known heterogeneity such as fibrosis, inflammation, and neurodegeneration. By analyzing small RNA genes, Gatehouse Bio aims to unlock the potential for innovative treatments that could significantly enhance patient outcomes.

Pear Bio is a biotechnology company based in Boston and London that focuses on developing precision medicine therapeutics for challenging cancer cases. By analyzing tumor biopsies and blood samples from patients, the company utilizes multi-omics approaches to identify new therapeutic targets. Their proprietary immune-microtumor system allows them to test the effectiveness of drug candidates directly on patient tumor samples. Pear Bio's innovative technology includes a specialized hydrogel that cultivates tumors outside the human body, effectively simulating drug resistance and streamlining the treatment selection process. This enables the identification of the most effective therapies for individual patients, thereby reducing the reliance on trial-and-error methods in cancer treatment.

Pear Bio is a biotechnology company based in Boston and London that focuses on developing precision medicine therapeutics for challenging cancer cases. By analyzing tumor biopsies and blood samples from patients, the company utilizes multi-omics approaches to identify new therapeutic targets. Their proprietary immune-microtumor system allows them to test the effectiveness of drug candidates directly on patient tumor samples. Pear Bio's innovative technology includes a specialized hydrogel that cultivates tumors outside the human body, effectively simulating drug resistance and streamlining the treatment selection process. This enables the identification of the most effective therapies for individual patients, thereby reducing the reliance on trial-and-error methods in cancer treatment.

BioROSA Technologies Inc. is a Belmont, Massachusetts-based company focused on developing blood tests for Autism Spectrum Disorders (ASD). Founded in 2018, the company aims to establish a biologically-based standard of care for ASD through innovative diagnostic tools. These tools enable clinicians to identify individuals at risk for ASD by utilizing blood-based biomarkers and advanced machine learning techniques. BioROSA’s platform not only enhances early detection and diagnosis but also supports therapeutic developments by facilitating patient stratification and assessing pharmacodynamics in clinical trials. This comprehensive approach equips healthcare professionals with the necessary resources to improve patient outcomes through timely intervention.

Pear Bio is a biotechnology company based in Boston and London that focuses on developing precision medicine therapeutics for challenging cancer cases. By analyzing tumor biopsies and blood samples from patients, the company utilizes multi-omics approaches to identify new therapeutic targets. Their proprietary immune-microtumor system allows them to test the effectiveness of drug candidates directly on patient tumor samples. Pear Bio's innovative technology includes a specialized hydrogel that cultivates tumors outside the human body, effectively simulating drug resistance and streamlining the treatment selection process. This enables the identification of the most effective therapies for individual patients, thereby reducing the reliance on trial-and-error methods in cancer treatment.

Catalog Technologies Inc. specializes in a DNA-based platform that revolutionizes digital data storage and computation. Founded in 2016 and headquartered in Boston, Massachusetts, the company provides a method for encoding digital information into DNA, making it a viable and cost-effective solution for long-term data archiving. By leveraging advanced synthetic biology technologies, Catalog aims to transform how information is stored, allowing customers to utilize DNA molecules as a primary medium for digital records. This innovative approach positions Catalog at the forefront of next-generation data storage solutions.

Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.

Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.

Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.

Farma Genetix is a Boston-based company that specializes in the manufacture of genetically tailored natural supplements and personalized diet plans aimed at addressing chronic health conditions. The company collaborates with researchers from Harvard Medical School's Genomics department to develop nutritional supplements designed to support cardiovascular health, including the maintenance of healthy blood pressure and cholesterol levels. Through its customized diet plans, Farma Genetix promotes a holistic approach to health that reinforces overall well-being and a healthy lifestyle.

Mori, formerly known as Overlook Research, is a company that develops a natural biopolymer coating designed to extend the shelf life of perishable foods. Founded in 2016 and headquartered in Boston, Massachusetts, Mori's innovative coating is made from proteins extracted from natural silk using salt and water. This protective layer helps slow the spoiling process of various food items, including fruits, vegetables, meat, and seafood, thereby reducing food waste. By focusing on sustainable and economical solutions, Mori aims to transform the food supply and enhance the efficiency of the food, agriculture, and packaging industries.

BioROSA Technologies Inc. is a Belmont, Massachusetts-based company focused on developing blood tests for Autism Spectrum Disorders (ASD). Founded in 2018, the company aims to establish a biologically-based standard of care for ASD through innovative diagnostic tools. These tools enable clinicians to identify individuals at risk for ASD by utilizing blood-based biomarkers and advanced machine learning techniques. BioROSA’s platform not only enhances early detection and diagnosis but also supports therapeutic developments by facilitating patient stratification and assessing pharmacodynamics in clinical trials. This comprehensive approach equips healthcare professionals with the necessary resources to improve patient outcomes through timely intervention.

Powerhouse Dynamics, Inc. is a technology firm based in Newton, Massachusetts, that specializes in enterprise energy and asset management systems tailored for small commercial facilities. Established in 2008, the company offers the SiteSage platform, which enables users to centralize the control, analysis, and management of energy-consuming equipment. This cloud-based system is designed for various sectors, including restaurants, convenience stores, and retail stores, and features modules for remote equipment and HVAC control, food safety, and utility bill management. SiteSage enhances operational efficiency by monitoring power consumption and equipment performance while providing advanced analytics through user-friendly online and mobile interfaces. The platform also includes tools for rebate management, deployment management, and support services, helping customers optimize energy use and reduce costs effectively. As of April 2019, Powerhouse Dynamics operates as a subsidiary of The Middleby Corporation.

Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.

ChefCharger Inc. is a Boston-based company that specializes in the development, manufacturing, and sale of integrated charging devices tailored for the hospitality industry, specifically restaurants, bars, and cafes. Founded in 2016, ChefCharger offers a range of multifunctional products that combine charging capabilities with traditional tabletop decor items such as candleholders, drink coasters, and customizable vases. These devices not only enable patrons to charge their mobile phones but are also connected to a cloud platform that allows for the display of targeted video advertisements. ChefCharger has evolved from a startup into a mature company, focusing on innovative wireless power and solar energy solutions, while also providing custom engineering at mass production levels.

Powerhouse Dynamics, Inc. is a technology firm based in Newton, Massachusetts, that specializes in enterprise energy and asset management systems tailored for small commercial facilities. Established in 2008, the company offers the SiteSage platform, which enables users to centralize the control, analysis, and management of energy-consuming equipment. This cloud-based system is designed for various sectors, including restaurants, convenience stores, and retail stores, and features modules for remote equipment and HVAC control, food safety, and utility bill management. SiteSage enhances operational efficiency by monitoring power consumption and equipment performance while providing advanced analytics through user-friendly online and mobile interfaces. The platform also includes tools for rebate management, deployment management, and support services, helping customers optimize energy use and reduce costs effectively. As of April 2019, Powerhouse Dynamics operates as a subsidiary of The Middleby Corporation.

BioROSA Technologies Inc. is a Belmont, Massachusetts-based company focused on developing blood tests for Autism Spectrum Disorders (ASD). Founded in 2018, the company aims to establish a biologically-based standard of care for ASD through innovative diagnostic tools. These tools enable clinicians to identify individuals at risk for ASD by utilizing blood-based biomarkers and advanced machine learning techniques. BioROSA’s platform not only enhances early detection and diagnosis but also supports therapeutic developments by facilitating patient stratification and assessing pharmacodynamics in clinical trials. This comprehensive approach equips healthcare professionals with the necessary resources to improve patient outcomes through timely intervention.

Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.

Bitome is a Boston-based company specializing in connected medical devices, focusing on noninvasive hydration monitoring technology. Established two years ago, Bitome's first product is designed to monitor hydration status, with significant applications in fields such as dialysis, diabetes management, sports performance, and maternal/fetal health. One of its primary uses is in assessing volume status in patients with congestive heart failure (CHF), a critical but challenging biometric to measure that is closely linked to patient outcomes. By enhancing hydration monitoring, Bitome aims to revolutionize CHF management in a manner similar to how glucose monitoring transformed diabetes care.

Powerhouse Dynamics, Inc. is a technology firm based in Newton, Massachusetts, that specializes in enterprise energy and asset management systems tailored for small commercial facilities. Established in 2008, the company offers the SiteSage platform, which enables users to centralize the control, analysis, and management of energy-consuming equipment. This cloud-based system is designed for various sectors, including restaurants, convenience stores, and retail stores, and features modules for remote equipment and HVAC control, food safety, and utility bill management. SiteSage enhances operational efficiency by monitoring power consumption and equipment performance while providing advanced analytics through user-friendly online and mobile interfaces. The platform also includes tools for rebate management, deployment management, and support services, helping customers optimize energy use and reduce costs effectively. As of April 2019, Powerhouse Dynamics operates as a subsidiary of The Middleby Corporation.

Mori, formerly known as Overlook Research, is a company that develops a natural biopolymer coating designed to extend the shelf life of perishable foods. Founded in 2016 and headquartered in Boston, Massachusetts, Mori's innovative coating is made from proteins extracted from natural silk using salt and water. This protective layer helps slow the spoiling process of various food items, including fruits, vegetables, meat, and seafood, thereby reducing food waste. By focusing on sustainable and economical solutions, Mori aims to transform the food supply and enhance the efficiency of the food, agriculture, and packaging industries.

Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.

Prospective Research, Inc. is a biotechnology company based in Beverly, Massachusetts, focused on developing innovative solutions for the aquaculture industry and antibiotic discovery. Established in 2015, the company utilizes its advanced technology platforms, including MicrobeMiner and GeneMiner, to access untapped antibiotics from soil-dwelling microbes. By employing microbial signaling molecules, Prospective Research creates feed incorporated preventative disease management solutions that eliminate the need for traditional antibiotics and medicated feed. Their approach involves modulating bacterial behavior and introducing trillions of beneficial bacteria into the microbiomes of farmed species such as fin-fish, shrimp, and shellfish. This technology enables the selective activation of genes that produce bio-active therapeutics, offering protection against various pathogens while enhancing the health of aquaculture species.

Catalog Technologies Inc. specializes in a DNA-based platform that revolutionizes digital data storage and computation. Founded in 2016 and headquartered in Boston, Massachusetts, the company provides a method for encoding digital information into DNA, making it a viable and cost-effective solution for long-term data archiving. By leveraging advanced synthetic biology technologies, Catalog aims to transform how information is stored, allowing customers to utilize DNA molecules as a primary medium for digital records. This innovative approach positions Catalog at the forefront of next-generation data storage solutions.

Prospective Research, Inc. is a biotechnology company based in Beverly, Massachusetts, focused on developing innovative solutions for the aquaculture industry and antibiotic discovery. Established in 2015, the company utilizes its advanced technology platforms, including MicrobeMiner and GeneMiner, to access untapped antibiotics from soil-dwelling microbes. By employing microbial signaling molecules, Prospective Research creates feed incorporated preventative disease management solutions that eliminate the need for traditional antibiotics and medicated feed. Their approach involves modulating bacterial behavior and introducing trillions of beneficial bacteria into the microbiomes of farmed species such as fin-fish, shrimp, and shellfish. This technology enables the selective activation of genes that produce bio-active therapeutics, offering protection against various pathogens while enhancing the health of aquaculture species.

Bitome is a Boston-based company specializing in connected medical devices, focusing on noninvasive hydration monitoring technology. Established two years ago, Bitome's first product is designed to monitor hydration status, with significant applications in fields such as dialysis, diabetes management, sports performance, and maternal/fetal health. One of its primary uses is in assessing volume status in patients with congestive heart failure (CHF), a critical but challenging biometric to measure that is closely linked to patient outcomes. By enhancing hydration monitoring, Bitome aims to revolutionize CHF management in a manner similar to how glucose monitoring transformed diabetes care.

Catalog Technologies Inc. specializes in a DNA-based platform that revolutionizes digital data storage and computation. Founded in 2016 and headquartered in Boston, Massachusetts, the company provides a method for encoding digital information into DNA, making it a viable and cost-effective solution for long-term data archiving. By leveraging advanced synthetic biology technologies, Catalog aims to transform how information is stored, allowing customers to utilize DNA molecules as a primary medium for digital records. This innovative approach positions Catalog at the forefront of next-generation data storage solutions.

Speedy Packets, Inc. is a technology company based in Cambridge, Massachusetts, founded in 2013. It specializes in developing cloud-based software solutions aimed at enhancing TCP performance across various network types, including fiber, cable, DSL, wireless, and satellite. The company's innovative software optimizes internet connections by applying coding to TCP packets, which reduces packet loss and minimizes retransmission requests. This results in significant improvements in end-to-end throughput and overall internet speed. Speedy Packets' technology enables businesses, service providers, and individuals to enjoy seamless online experiences, facilitating activities such as streaming videos, uploading content, and transferring files efficiently.

Powerhouse Dynamics, Inc. is a technology firm based in Newton, Massachusetts, that specializes in enterprise energy and asset management systems tailored for small commercial facilities. Established in 2008, the company offers the SiteSage platform, which enables users to centralize the control, analysis, and management of energy-consuming equipment. This cloud-based system is designed for various sectors, including restaurants, convenience stores, and retail stores, and features modules for remote equipment and HVAC control, food safety, and utility bill management. SiteSage enhances operational efficiency by monitoring power consumption and equipment performance while providing advanced analytics through user-friendly online and mobile interfaces. The platform also includes tools for rebate management, deployment management, and support services, helping customers optimize energy use and reduce costs effectively. As of April 2019, Powerhouse Dynamics operates as a subsidiary of The Middleby Corporation.

Bitome is a Boston-based company specializing in connected medical devices, focusing on noninvasive hydration monitoring technology. Established two years ago, Bitome's first product is designed to monitor hydration status, with significant applications in fields such as dialysis, diabetes management, sports performance, and maternal/fetal health. One of its primary uses is in assessing volume status in patients with congestive heart failure (CHF), a critical but challenging biometric to measure that is closely linked to patient outcomes. By enhancing hydration monitoring, Bitome aims to revolutionize CHF management in a manner similar to how glucose monitoring transformed diabetes care.

Prospective Research, Inc. is a biotechnology company based in Beverly, Massachusetts, focused on developing innovative solutions for the aquaculture industry and antibiotic discovery. Established in 2015, the company utilizes its advanced technology platforms, including MicrobeMiner and GeneMiner, to access untapped antibiotics from soil-dwelling microbes. By employing microbial signaling molecules, Prospective Research creates feed incorporated preventative disease management solutions that eliminate the need for traditional antibiotics and medicated feed. Their approach involves modulating bacterial behavior and introducing trillions of beneficial bacteria into the microbiomes of farmed species such as fin-fish, shrimp, and shellfish. This technology enables the selective activation of genes that produce bio-active therapeutics, offering protection against various pathogens while enhancing the health of aquaculture species.

Crowdly is an advocate marketing platform based in Boston, Massachusetts, that enables large consumer brands to connect with and activate their authentic advocates. Founded in 2011, the company focuses on enhancing word-of-mouth promotion and brand advocacy by allowing brands to build a community of engaged supporters. Through its platform, Crowdly provides insights into advocate behavior, helping companies strengthen their branding efforts and achieve a higher return on investment. The company operates within the realms of finance, social media, advertising, and marketing, offering a comprehensive solution for brands seeking to leverage the power of advocacy in their marketing strategies.

Lotus Scoop is a Brooklyn-based company that specializes in producing and selling ice cream, offering a unique range of flavors that combine whole fruits with fresh vegetables. The ice creams are crafted using clean ingredients and local dairy, with an emphasis on artisan techniques. Customers can find Lotus Scoop products at Whole Foods Market and other retailers primarily located in New York, New Jersey, and Connecticut. The company also provides an online ordering option, allowing customers to explore its sophisticated and craft-driven ice cream offerings, which include an array of Caribbean, Latin American, and Southern-inspired flavors.

Powerhouse Dynamics, Inc. is a technology firm based in Newton, Massachusetts, that specializes in enterprise energy and asset management systems tailored for small commercial facilities. Established in 2008, the company offers the SiteSage platform, which enables users to centralize the control, analysis, and management of energy-consuming equipment. This cloud-based system is designed for various sectors, including restaurants, convenience stores, and retail stores, and features modules for remote equipment and HVAC control, food safety, and utility bill management. SiteSage enhances operational efficiency by monitoring power consumption and equipment performance while providing advanced analytics through user-friendly online and mobile interfaces. The platform also includes tools for rebate management, deployment management, and support services, helping customers optimize energy use and reduce costs effectively. As of April 2019, Powerhouse Dynamics operates as a subsidiary of The Middleby Corporation.

Speedy Packets, Inc. is a technology company based in Cambridge, Massachusetts, founded in 2013. It specializes in developing cloud-based software solutions aimed at enhancing TCP performance across various network types, including fiber, cable, DSL, wireless, and satellite. The company's innovative software optimizes internet connections by applying coding to TCP packets, which reduces packet loss and minimizes retransmission requests. This results in significant improvements in end-to-end throughput and overall internet speed. Speedy Packets' technology enables businesses, service providers, and individuals to enjoy seamless online experiences, facilitating activities such as streaming videos, uploading content, and transferring files efficiently.

Miramix is a Massachusetts-based company that specializes in producing customized nutritional supplements tailored to individual health goals. The company offers a unique marketplace where consumers can select modular and combinable blends to create personalized supplements, including custom, whole food, and private label options. Utilizing micro-dosing technology, Miramix provides both the hardware and software necessary for users to formulate their own vitamin and health supplement mixes with precision. Their product range encompasses workout supplements, beauty supplements, and more, catering to a diverse clientele seeking specific nutrient solutions.

Prospective Research, Inc. is a biotechnology company based in Beverly, Massachusetts, focused on developing innovative solutions for the aquaculture industry and antibiotic discovery. Established in 2015, the company utilizes its advanced technology platforms, including MicrobeMiner and GeneMiner, to access untapped antibiotics from soil-dwelling microbes. By employing microbial signaling molecules, Prospective Research creates feed incorporated preventative disease management solutions that eliminate the need for traditional antibiotics and medicated feed. Their approach involves modulating bacterial behavior and introducing trillions of beneficial bacteria into the microbiomes of farmed species such as fin-fish, shrimp, and shellfish. This technology enables the selective activation of genes that produce bio-active therapeutics, offering protection against various pathogens while enhancing the health of aquaculture species.

Harmonix Music Systems, Inc. is a video game development studio founded in 1995 and based in Cambridge, Massachusetts. The company specializes in music-oriented games, allowing users to engage with music through interactive gameplay across various platforms, including console, PC, and mobile. Harmonix is best known for its successful franchises such as Rock Band and Dance Central, as well as its role in developing the original Guitar Hero series. The studio aims to provide a unique experience that enables both musicians and non-musicians to enjoy the creative process of making music through gaming.

Speedy Packets, Inc. is a technology company based in Cambridge, Massachusetts, founded in 2013. It specializes in developing cloud-based software solutions aimed at enhancing TCP performance across various network types, including fiber, cable, DSL, wireless, and satellite. The company's innovative software optimizes internet connections by applying coding to TCP packets, which reduces packet loss and minimizes retransmission requests. This results in significant improvements in end-to-end throughput and overall internet speed. Speedy Packets' technology enables businesses, service providers, and individuals to enjoy seamless online experiences, facilitating activities such as streaming videos, uploading content, and transferring files efficiently.

Crowdly is an advocate marketing platform based in Boston, Massachusetts, that enables large consumer brands to connect with and activate their authentic advocates. Founded in 2011, the company focuses on enhancing word-of-mouth promotion and brand advocacy by allowing brands to build a community of engaged supporters. Through its platform, Crowdly provides insights into advocate behavior, helping companies strengthen their branding efforts and achieve a higher return on investment. The company operates within the realms of finance, social media, advertising, and marketing, offering a comprehensive solution for brands seeking to leverage the power of advocacy in their marketing strategies.

The Tap Lab is a mobile gaming company located in Cambridge, Massachusetts, focused on developing innovative games for a new generation of players. The company creates engaging mobile experiences that encourage players to explore and interact with their surroundings in unique ways. By blending imaginative gameplay with real-world elements, The Tap Lab aims to captivate game enthusiasts and expand the possibilities of mobile gaming.

Cobalt Software, Inc. is a financial technology company based in Boston, Massachusetts, specializing in software solutions for private equity and venture capital firms. Founded in 2011, the company offers a range of tools designed to analyze, benchmark, and monitor private market data and fund performance. Their primary products include the Fund Launch, which validates performance track records for potential investors; the Performance Calculator, which compares fund and portfolio performance against peers and market indices; and the Deal Calculator, which provides insights on operational changes in portfolio companies and their impact on returns. Cobalt Software's offerings facilitate performance reporting, cash flow tracking, manager selection, and benchmarking, thereby enhancing the decision-making processes of finance, management, and investor relations teams. The company has established a strategic partnership with Hamilton Lane to further enhance its service capabilities.

Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.

The Tap Lab is a mobile gaming company located in Cambridge, Massachusetts, focused on developing innovative games for a new generation of players. The company creates engaging mobile experiences that encourage players to explore and interact with their surroundings in unique ways. By blending imaginative gameplay with real-world elements, The Tap Lab aims to captivate game enthusiasts and expand the possibilities of mobile gaming.

Powerhouse Dynamics, Inc. is a technology firm based in Newton, Massachusetts, that specializes in enterprise energy and asset management systems tailored for small commercial facilities. Established in 2008, the company offers the SiteSage platform, which enables users to centralize the control, analysis, and management of energy-consuming equipment. This cloud-based system is designed for various sectors, including restaurants, convenience stores, and retail stores, and features modules for remote equipment and HVAC control, food safety, and utility bill management. SiteSage enhances operational efficiency by monitoring power consumption and equipment performance while providing advanced analytics through user-friendly online and mobile interfaces. The platform also includes tools for rebate management, deployment management, and support services, helping customers optimize energy use and reduce costs effectively. As of April 2019, Powerhouse Dynamics operates as a subsidiary of The Middleby Corporation.

Formlabs Inc. is a company that designs and manufactures advanced 3D printing systems targeted at engineers, designers, and artists. Established in 2011 and headquartered in Somerville, Massachusetts, Formlabs offers a diverse range of products, including the Form 3, Form 3B, and Form 3L printers, all utilizing Low Force Stereolithography (LFS) technology. The company also provides post-processing solutions such as Form Wash and Form Cure, as well as the Fuse 1 SLS 3D printer and the Form Cell manufacturing solution. Formlabs develops high-performance materials for various applications in industries like dental, healthcare, jewelry, and education. Its PreForm software facilitates the preparation of models for printing, making it a preferred choice among professionals worldwide. With additional offices in Germany, Japan, China, Singapore, Hungary, and North Carolina, Formlabs continues to innovate in the field of 3D printing, enhancing the capabilities of digital fabrication.

Collaborate.com offers a cloud-based team collaboration platform designed for the mobile workforce, integrating document sharing, task management, and communication into a single application accessible on iPhone, Android, and the Web. Founded in 2011 by entrepreneurs Matt Cutler and David Greenstein, the platform allows teams to quickly begin collaborating by leveraging its compatibility with popular cloud services such as Box, Dropbox, Evernote, Google Drive, and Apple iCloud. Users can access Collaborate.com via its website or by downloading the app from the App Store or Google Play. The company is based in Boston and supported by various investors, including Google Ventures and others.

Formlabs Inc. is a company that designs and manufactures advanced 3D printing systems targeted at engineers, designers, and artists. Established in 2011 and headquartered in Somerville, Massachusetts, Formlabs offers a diverse range of products, including the Form 3, Form 3B, and Form 3L printers, all utilizing Low Force Stereolithography (LFS) technology. The company also provides post-processing solutions such as Form Wash and Form Cure, as well as the Fuse 1 SLS 3D printer and the Form Cell manufacturing solution. Formlabs develops high-performance materials for various applications in industries like dental, healthcare, jewelry, and education. Its PreForm software facilitates the preparation of models for printing, making it a preferred choice among professionals worldwide. With additional offices in Germany, Japan, China, Singapore, Hungary, and North Carolina, Formlabs continues to innovate in the field of 3D printing, enhancing the capabilities of digital fabrication.

Powerhouse Dynamics, Inc. is a technology firm based in Newton, Massachusetts, that specializes in enterprise energy and asset management systems tailored for small commercial facilities. Established in 2008, the company offers the SiteSage platform, which enables users to centralize the control, analysis, and management of energy-consuming equipment. This cloud-based system is designed for various sectors, including restaurants, convenience stores, and retail stores, and features modules for remote equipment and HVAC control, food safety, and utility bill management. SiteSage enhances operational efficiency by monitoring power consumption and equipment performance while providing advanced analytics through user-friendly online and mobile interfaces. The platform also includes tools for rebate management, deployment management, and support services, helping customers optimize energy use and reduce costs effectively. As of April 2019, Powerhouse Dynamics operates as a subsidiary of The Middleby Corporation.

Collaborate.com offers a cloud-based team collaboration platform designed for the mobile workforce, integrating document sharing, task management, and communication into a single application accessible on iPhone, Android, and the Web. Founded in 2011 by entrepreneurs Matt Cutler and David Greenstein, the platform allows teams to quickly begin collaborating by leveraging its compatibility with popular cloud services such as Box, Dropbox, Evernote, Google Drive, and Apple iCloud. Users can access Collaborate.com via its website or by downloading the app from the App Store or Google Play. The company is based in Boston and supported by various investors, including Google Ventures and others.

SocialSci is an online platform tailored for academic researchers to conduct scientific surveys and in-lab studies. Founded in 2009 and based in Cambridge, Massachusetts, it enables users to design surveys through an intuitive drag-and-drop interface. The platform features a built-in recruitment system that rewards participants with points while effectively screening repeat visitors. SocialSci facilitates the discovery of local studies seeking live participants, thereby connecting researchers with potential subjects. With its user-friendly tools, the platform supports colleges and universities across the United States, allowing researchers to create unlimited surveys and collect extensive responses efficiently.

Powerhouse Dynamics, Inc. is a technology firm based in Newton, Massachusetts, that specializes in enterprise energy and asset management systems tailored for small commercial facilities. Established in 2008, the company offers the SiteSage platform, which enables users to centralize the control, analysis, and management of energy-consuming equipment. This cloud-based system is designed for various sectors, including restaurants, convenience stores, and retail stores, and features modules for remote equipment and HVAC control, food safety, and utility bill management. SiteSage enhances operational efficiency by monitoring power consumption and equipment performance while providing advanced analytics through user-friendly online and mobile interfaces. The platform also includes tools for rebate management, deployment management, and support services, helping customers optimize energy use and reduce costs effectively. As of April 2019, Powerhouse Dynamics operates as a subsidiary of The Middleby Corporation.

Green Earth Technologies, Inc. is a green clean tech company that develops and sells bio-based performance and cleaning products across various markets, including oil and gas well services, automotive aftermarket, outdoor power equipment, and marine applications. The company offers a diverse range of products, such as well stimulation agents, storage tank cleaners, motor oils, and automotive appearance products. Its product lines include well services products, lubricants, and cleaning chemicals, marketed under brands like G-CLEAN, G-OIL, and G-MARINE. Green Earth Technologies emphasizes environmentally friendly practices by utilizing domestically sourced renewable feedstocks and proprietary technologies focused on biodegradability, recyclability, and safety for the environment. The company distributes its products through various channels, including direct sales, distribution agreements, and online platforms, catering to home centers, retail outlets, automotive stores, and equipment manufacturers. Founded in 2007 and based in Greenwich, Connecticut, Green Earth Technologies aims to provide sustainable solutions in the cleaning and lubrication sectors.

Harmonix Music Systems, Inc. is a video game development studio founded in 1995 and based in Cambridge, Massachusetts. The company specializes in music-oriented games, allowing users to engage with music through interactive gameplay across various platforms, including console, PC, and mobile. Harmonix is best known for its successful franchises such as Rock Band and Dance Central, as well as its role in developing the original Guitar Hero series. The studio aims to provide a unique experience that enables both musicians and non-musicians to enjoy the creative process of making music through gaming.

Harmonix Music Systems, Inc. is a video game development studio founded in 1995 and based in Cambridge, Massachusetts. The company specializes in music-oriented games, allowing users to engage with music through interactive gameplay across various platforms, including console, PC, and mobile. Harmonix is best known for its successful franchises such as Rock Band and Dance Central, as well as its role in developing the original Guitar Hero series. The studio aims to provide a unique experience that enables both musicians and non-musicians to enjoy the creative process of making music through gaming.

Net.Genesis Corp. provides software and professional services that help its customers understand, analyze and improve their online businesses. Its software enables companies to collect, store, organize, and analyze detailed information about the online behavior of customers and other visitors on their web sites. Net.Genesis software also enables its customers to import and analyze information about e-customers from other online and off-line software systems and databases. In addition, the company offers professional services including strategic analytic consulting, product implementation, application integration, training programs, and technical support services. The company markets its products and related services in United States, Europe, and Australia. It was founded in 1994 and is headquartered in Cambridge, Massachusetts. As of December 21, 2001, net.Genesis Corp. was acquired by SPSS Inc.