SOSV

Capro-X Inc. is an ag-tech company focused on enhancing sustainability in the dairy industry by addressing the issue of acid whey waste, particularly from Greek yogurt production. Founded in 2017 and based in Ithaca, New York, Capro-X has developed a fermentation bioprocess technology known as WheyAway. This innovative treatment utilizes naturally occurring, non-GMO microbes to convert dairy waste streams into clean water and valuable bio-oils. The process occurs at the site of waste generation, allowing for efficient management of by-products. Capro-X also produces caproic acid, marketed as CPRX1060, which further contributes to the upcycling of dairy waste into useful materials. Through its solutions, the company aims to promote sustainability and improve operational efficiency within the dairy sector.

Particle provides hardware and software tools to help users prototype, scale, and manage IoT products. Particle is an IoT device platform that enables businesses to easily add the power of connectivity to any product. From hardware to connectivity to device management and cloud, Particle provides developers with tools to prototype IoT solutions quickly as well as a reliable and secure platform for enterprises to scale. Over 150,000 product builders in more than 170 countries and half of the Fortune 500 have deployed connected IoT devices powered by Particle. Listed as one of Fast Company’s Most Innovative Companies of 2015 and named as a major player to watch in the IoT Landscape in IDC Marketscape’s 2018 Vendor Assessment, Particle’s customers include NASA, SpaceX, consumer hot tub manufacturer Jacuzzi, and coffee-brewing pioneer Keurig. Venture backed by Root Ventures, Spark Capital, and Qualcomm Ventures. Particle is based in San Francisco, CA and Shenzhen, China. Particle was founded on 2012.

Prellis Biologics, Inc. specializes in creating human tissues for drug development and the eventual production of human organs for transplantation. Founded in 2016 and based in San Francisco, California, the company employs advanced bioprinting technology to develop vascularized human tissues and organs, aiming to overcome the challenges associated with microvasculature. Its innovative products include TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X. Prellis Biologics also focuses on accurately replicating the human immune response through lymph node organoids, which can be utilized for various applications such as antibody discovery and immunogenicity assessment. By addressing critical issues in early-stage drug development and translational pharmacology, Prellis Biologics seeks to improve patient outcomes in healthcare.

Abbot's Butcher, Inc. is a producer and marketer of plant-based meat products, established in 2016 and located in San Clemente, California. The company specializes in crafting gourmet, small-batch meat alternatives that are allergen-friendly and made from whole food ingredients. Its product line includes a variety of offerings such as chopped chick’n, beef sausage, chorizo, turkey burgers, herb-roasted chicken deli slices, Italian meatballs, and ground chicken and beef, all created using high-quality vegetables, herbs, and spices. Abbot's Butcher aims to provide consumers with accessible plant-based protein options that cater to diverse dietary preferences.

Hyperlume Inc., based in Ottawa, Canada, specializes in developing advanced optical connectivity solutions. The company focuses on high-performance computing, artificial intelligence, and high-end processors, aiming to enhance data transfer speeds and enable scalable optical interconnects for edge computing platforms.

Somatic LLC, founded in 2017 and based in New York, specializes in robotic cleaning services for commercial bathrooms. The company develops advanced cleaning robots designed to enhance efficiency in restroom maintenance within office buildings. These robots utilize a virtual reality programming system to spray and wipe down surfaces effectively. Additionally, they are equipped with capabilities to open doors and operate elevators, which streamlines the cleaning process. By implementing Somatic's technology, clients can significantly reduce cleaning costs and improve staff retention while also enhancing overall hygiene in their facilities.

Tensorfield Agriculture, founded in 2018 and based in San Jose, California, develops innovative agricultural machinery tailored for specialty row crops. The company focuses on creating robots equipped with computer vision technology that perform selective, non-invasive weeding without the use of herbicides, utilizing thermal micro-dosing techniques. This approach addresses the growing concern of herbicide resistance, allowing farmers to cultivate crops sustainably while ensuring the continued supply of safe, fresh food. Tensorfield Agriculture is supported by the HAX hardware accelerator and has received investment from the global venture capital firm SOSV, positioning it at the forefront of agricultural innovation in a post-herbicide landscape.

Proton Intelligence is a Canadian company, founded in 2020 and based in Vancouver, that specializes in biomarker monitoring to assist in managing chronic diseases and improving patient outcomes. The company has developed a wearable continuous potassium monitoring platform aimed at individuals with hyperkalemia, particularly those suffering from chronic kidney disease and other co-morbidities. By providing accurate and real-time potassium measurements through interstitial fluid analysis, Proton Intelligence facilitates critical health monitoring for both clinicians and patients. This technology enables informed decision-making regarding medications, diet, and treatment options, thereby enhancing the management of hyperkalemia and promoting better overall health for affected individuals.

Ten63 Therapeutics is a biotechnology company focused on developing innovative therapeutics for challenging diseases, particularly those involving targets previously considered undruggable. Founded in 2017 and based in Chapel Hill, North Carolina, the company utilizes its proprietary platform, COPPER, which integrates advanced artificial intelligence and state-of-the-art physical models to explore vast chemical spaces. By employing low-residual, machine learning-based computational chemistry alongside superlinear search algorithms, Ten63 Therapeutics aims to identify and optimize drug candidates effectively. Their approach includes proprietary scaffold redesign and hopping technology, enabling the screening of trillions of molecules to predict resistance and redesign antibodies. This combination of techniques positions Ten63 Therapeutics at the forefront of developing durable treatments for some of the most lethal diseases.

AlkaLi Labs is a biotechnology research company based in San Francisco, California, established in 2023. The company focuses on developing biological solutions to harness domestic mineral resources. Currently operating in stealth mode, AlkaLi Labs aims to innovate in the field of biotechnology, leveraging biological processes to unlock valuable minerals.

Brightwater Tools, headquartered in Vermont, is a woman-led startup specializing in sustainable sanitation solutions. The company has developed a unique building-scale wastewater nutrient recovery system that transforms high-strength wastewater into natural, nutrient-rich fertilizer. This process not only reduces harmful algal blooms in waterways but also promotes a circular economy by recycling nutrients. The system comprises three proprietary pieces of equipment, each facilitating key wastewater processes and available for individual or collective purchase. Brightwater Tools aims to become a significant equipment provider in this sector, with a strong customer base expected upon completion of its prototype and beta testing.

Renewell is a company based in Bakersfield, California, that transforms inactive oil and gas wells into gravity-based energy storage systems. This innovative process involves lowering a weight connected to a regenerative winch down a repurposed wellbore, allowing for the storage of energy during periods of low demand and the release of electricity back to the grid when demand increases. By utilizing existing oil and gas infrastructure, Renewell aims to create a flexible and cost-effective energy storage network while significantly reducing greenhouse gas emissions. The company's technology focuses on zero-self-discharge renewable energy storage, contributing to a more sustainable energy future.

OneSkin Inc. is a biotechnology company focused on developing innovative solutions to enhance skin health and combat aging. Founded by a team of PhDs and longevity scientists, the company has created a proprietary peptide, OS-01, which has been validated to reduce the biological age of skin by minimizing the accumulation of aged cells, enhancing cellular repair, and fortifying the epidermal barrier. OneSkin offers a flagship product, the OS-01 Topical Supplement, which is designed to be suitable for all skin types and is made from high-quality vegan ingredients. In addition to its product line, OneSkin specializes in creating advanced 3D human skin models for research and testing purposes, providing in vitro services to assess the efficacy and safety of cosmetic ingredients without the use of animals. Incorporated in 2016 and based in San Francisco, OneSkin is dedicated to advancing the understanding of skin biology and developing effective anti-aging solutions.

Laguna Bio is a biotechnology company based in Berkeley, California, founded in 2022. The company focuses on drug discovery, specifically developing a platform that activates and expands the innate immune system to combat cancer. Laguna Bio specializes in enhancing a specific type of T cell that targets solid tumors, aiming to improve the efficacy of bispecific antibody drugs. By increasing the immune response against these tumors, the company seeks to provide innovative solutions that may help patients survive cancer more effectively.

Terran Robotics is a construction company based in Bloomington, Indiana, that focuses on innovative home construction services, particularly in automated adobe wall building. The company utilizes artificial intelligence and robotics to enhance traditional earthen building techniques. By employing a custom-designed cable-driven robot for three-dimensional printing of homes, Terran Robotics aims to improve durability with features such as fire resistance and superior sound dampening. This approach enables clients to significantly reduce housing costs, lower energy expenses, and maintain an environmentally friendly footprint.

Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.

Gatehouse Bio is a biotechnology company based in Waltham, Massachusetts, focused on the accelerated development of therapies utilizing small ribonucleic acid (RNA) and advanced bioinformatics. Founded in 2016, the company has developed a platform that employs artificial intelligence to identify error-free RNA biomarkers and discover disease-associated mutations. This platform enables precise classification of patient samples, which aids in the design of targeted therapeutics aimed at addressing various diseases, particularly in areas characterized by known heterogeneity such as fibrosis, inflammation, and neurodegeneration. By analyzing small RNA genes, Gatehouse Bio aims to unlock the potential for innovative treatments that could significantly enhance patient outcomes.

Tensorfield Agriculture, founded in 2018 and based in San Jose, California, develops innovative agricultural machinery tailored for specialty row crops. The company focuses on creating robots equipped with computer vision technology that perform selective, non-invasive weeding without the use of herbicides, utilizing thermal micro-dosing techniques. This approach addresses the growing concern of herbicide resistance, allowing farmers to cultivate crops sustainably while ensuring the continued supply of safe, fresh food. Tensorfield Agriculture is supported by the HAX hardware accelerator and has received investment from the global venture capital firm SOSV, positioning it at the forefront of agricultural innovation in a post-herbicide landscape.

Capro-X Inc. is an ag-tech company focused on enhancing sustainability in the dairy industry by addressing the issue of acid whey waste, particularly from Greek yogurt production. Founded in 2017 and based in Ithaca, New York, Capro-X has developed a fermentation bioprocess technology known as WheyAway. This innovative treatment utilizes naturally occurring, non-GMO microbes to convert dairy waste streams into clean water and valuable bio-oils. The process occurs at the site of waste generation, allowing for efficient management of by-products. Capro-X also produces caproic acid, marketed as CPRX1060, which further contributes to the upcycling of dairy waste into useful materials. Through its solutions, the company aims to promote sustainability and improve operational efficiency within the dairy sector.

Unspun, Inc., founded in 2015 and based in San Francisco, California, specializes in the development of a platform that creates customized jeans using advanced body scanning technology, fit algorithms, and additive manufacturing. The company aims to address environmental concerns by reducing global carbon emissions through automated and localized manufacturing processes. Unspun’s innovative approach not only eliminates pattern-cutting waste and unsold inventory but also allows for the production of jeans in under ten minutes in a zero-waste manner. Their technology is showcased through the unspun.io platform, which provides digital customization solutions for various apparel brands. With a mission to make fashion more sustainable, Unspun is positioned at the intersection of robotics and digital apparel, striving to transform the industry with its unique approach to on-demand manufacturing.

Situated in San Francisco, California, the company is presently functioning in stealth mode.

Kegg is a fertility tracking device that combines the functions of monitoring vaginal fluid and facilitating pelvic floor exercises. Founded in 2017 and based in San Francisco, California, Kegg utilizes advanced sensing technology to detect changes in cervical fluid, thereby enabling women to identify their fertile window and ovulation up to seven days in advance. This innovative approach provides essential data that enhances the diagnosis, monitoring, and treatment of women's reproductive health, significantly increasing the chances of natural conception. By offering an intuitive and effective solution, Kegg empowers women with the information they need to make informed decisions regarding their fertility.

CellCrine focuses on discovering enzymes that transform cell culture for the cell-based meats industry. CellCrine was founded in 2021and was headquartered in United, States.

Particle provides hardware and software tools to help users prototype, scale, and manage IoT products. Particle is an IoT device platform that enables businesses to easily add the power of connectivity to any product. From hardware to connectivity to device management and cloud, Particle provides developers with tools to prototype IoT solutions quickly as well as a reliable and secure platform for enterprises to scale. Over 150,000 product builders in more than 170 countries and half of the Fortune 500 have deployed connected IoT devices powered by Particle. Listed as one of Fast Company’s Most Innovative Companies of 2015 and named as a major player to watch in the IoT Landscape in IDC Marketscape’s 2018 Vendor Assessment, Particle’s customers include NASA, SpaceX, consumer hot tub manufacturer Jacuzzi, and coffee-brewing pioneer Keurig. Venture backed by Root Ventures, Spark Capital, and Qualcomm Ventures. Particle is based in San Francisco, CA and Shenzhen, China. Particle was founded on 2012.

Avidbots, established in 2014 and headquartered in Ottawa, Canada, specializes in developing and manufacturing autonomous commercial floor cleaning robots. Their flagship product, NEO, uses laser mapping technology to efficiently clean and maintain large spaces in various industries, including airports, retail malls, hospitals, and warehouses. NEO operates alongside human cleaning crews, allowing them to focus on higher-value tasks while the robot handles repetitive floor scrubbing. The company's mission is to integrate robots into everyday life to enhance human potential.

Prolific Machines is a biotechnology company based in San Francisco, California, founded in 2020. It specializes in developing advanced cell technologies aimed at transforming the production of cells for sustainable applications, particularly in the cultivated meat industry. The company focuses on high-scale precision cell-differentiation techniques that enhance the efficiency, quality, reproducibility, and sustainability of cell production. Additionally, Prolific Machines is engaged in research and development efforts related to clean meat and cell therapies, utilizing innovative approaches to create better sustainable options. Through its work, the company aims to promote a healthier future for both humanity and the planet.

EIO Diagnostics Inc. is a Canadian company specializing in mastitis detection systems for dairy cattle. Founded in 2017 and based in Duncan, the company has developed the FirstLook Mastitis system, which employs a multispectral sensor to capture images of the udder as cows enter the milk parlor. This technology utilizes infrared image analysis and computer vision to automate the detection of early indicators of mastitis, allowing farmers to prevent infections before they occur. By installing a single sensor at the entry of the rotary milking system, EIO Diagnostics enables farmers to monitor udder health efficiently, thereby enhancing livestock health and improving milk quality while reducing labor and associated costs.

Lief Therapeutics is a medical device company focused on improving at-home care for individuals suffering from post-traumatic stress disorder, depression, and anxiety. The company has developed a discreet biosensing patch that measures heart rate and breathing patterns with medical accuracy. This wearable device, known as Lief, helps users manage their stress responses through biofeedback exercises, allowing them to monitor their emotions and behaviors in real-time. Additionally, the device provides clinicians with insights into patient progress, enabling in-session training and tracking of psychological assessments. Lief Therapeutics also offers the Lief Health Score application, which records thoughts, emotions, and sensations, facilitating the tracking of daily progress and personalized practice exercises. Founded in 2014 and based in San Francisco, California, the company sells its products online.

Avidbots, established in 2014 and headquartered in Ottawa, Canada, specializes in developing and manufacturing autonomous commercial floor cleaning robots. Their flagship product, NEO, uses laser mapping technology to efficiently clean and maintain large spaces in various industries, including airports, retail malls, hospitals, and warehouses. NEO operates alongside human cleaning crews, allowing them to focus on higher-value tasks while the robot handles repetitive floor scrubbing. The company's mission is to integrate robots into everyday life to enhance human potential.

Helex, founded in 2021 and based in New York, specializes in developing innovative genomic medicines specifically for renal conditions. The company leverages its proprietary genomics data and bioinformatics platform to create, verify, and distribute therapy-specific guide RNAs (gRNAs). By employing data-driven deep-learning models and high throughput next-generation sequencing data from CRISPR edits on human cell lines, Helex provides reliable predictions and validations in-house. This approach supports clients in expediting the development of CRISPR-based drug discovery and cell and gene therapies, emphasizing non-viral targeted delivery and genome editing for kidney-related therapies.

Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on growing marine-animal cells to create alternatives to traditional fish and seafood, including bluefin tuna. By offering a variety of responsibly produced food options, Finless Foods aims to cater to diverse tastes and dietary needs while promoting sustainability and better ocean health. The company's innovative approach provides consumers with healthy and accessible seafood alternatives, enabling them to maintain a balanced diet without compromising on flavor or variety.

California Organic Fertilizers specializes in the production of certified organic fertilizers designed for agricultural use, particularly for organic farms. The company offers both liquid and dry fertilizers that are compliant with food safety standards and the National Organic Program. Sourced from local raw materials, these fertilizers provide high plant-available nitrogen, which is essential for promoting healthy crop growth. California Organic Fertilizers prioritizes the well-being of its workforce, communities, and the environment, ensuring that its products are suitable for organic farming operations as well as commercial landscape applications.

California Cultured is a food company based in Davis, California, that specializes in producing sustainable, lab-grown cocoa through advanced cellular agriculture techniques. Founded in 2020, the company aims to create cocoa that is less bitter and requires less sugar, enhancing the taste while promoting health benefits. By stimulating cocoa cells with common food ingredients, California Cultured ensures the growth of premium-quality cocoa without the ethical and environmental issues associated with traditional cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious cocoa products that are both sustainable and socially responsible.

Strados Labs, LLC is a medical technology company based in Philadelphia, Pennsylvania, that focuses on innovating respiratory health management through advanced biosensors and artificial intelligence. Founded in 2016, Strados Labs develops a wearable device that provides real-time insights into respiratory metrics such as breathing speed, sounds, and patterns. This device is equipped with a continuous breathing sensor that enables remote monitoring of patients with respiratory conditions like asthma and chronic obstructive pulmonary disease. By connecting the device to a mobile application, patients and healthcare providers can access critical respiratory data, facilitating informed decision-making and improved management of respiratory health.

Contextere Corporation is an industrial IoT software company founded in 2015 and based in Ottawa, Canada. The company focuses on enhancing human performance through its intelligent personal agent, which provides actionable insights at the last tactical mile of industrial operations. Contextere's software utilizes artificial intelligence and machine learning to extract and structure previously inaccessible maintenance, repair, and operations data. This capability enables clients, including global corporations, to improve productivity, enhance safety, and minimize equipment downtime. By delivering immediate insights, Contextere aids organizations in increasing situational awareness and managing dynamic data environments effectively, ultimately reducing cognitive overload for the workforce.

AquaLith Advanced Materials specializes in the development of innovative lithium-ion battery materials. The company has secured exclusive rights to a portfolio of patents from the University of Maryland, which focus on advancements made by researchers in the field of chemical and materials engineering. AquaLith's technology includes an ultra-high energy cathode, a novel silicon anode, and a non-flammable aqueous electrolyte, all designed to enhance the performance of lithium-ion batteries. This technology addresses key challenges such as efficiency in low temperatures, faster charging times, and improved safety by reducing fire risks associated with short circuits. The company's materials aim to provide high energy density while being cost-effective and abundant, ultimately benefiting consumer electronics and other applications in need of reliable battery solutions.

Avisa Myko Inc. is a biotechnology company based in San Francisco, California, specializing in the production of natural, water-soluble melanin. The company has developed a patented technology that allows for the large-scale and cost-effective manufacturing of melanin, which is used across various industries, including cosmetics, biomedicine, and environmental applications. Avisa Myko's melanin offers protection against ionizing radiation and is integrated into products such as latex, fabrics, laminated plastics, and glass. Additionally, the company is working on formulating a sunscreen that utilizes melanin as a natural ultraviolet blocker, eliminating the need for traditional chemical or mineral UV filters. By focusing on sustainable solutions, Avisa Myko aims to enhance human health and environmental safety through its innovative melanin products.

XN Health is a medical device company based in Texas, founded in 2021. The company specializes in developing healthcare devices aimed at improving the process of mechanical ventilation. Its innovative technology focuses on phrenic nerve stimulation, which induces diaphragm contractions during ventilation. This approach helps protect against diaphragm dysfunction in patients who are mechanically ventilated, ultimately enabling them to wean off the ventilator more quickly and safely.

Farmshelf Corp. is a Brooklyn-based company founded in 2015 that specializes in designing and managing modular urban farms. The company offers an automated indoor farming solution that allows customers, including homes and restaurants, to grow a variety of fruits and vegetables. Farmshelf's compact, bookcase-sized farms can produce significant amounts of fresh produce weekly, growing food three times faster than traditional farming methods while using 90 percent less water. The hydroponic system automatically manages watering and nutrient delivery, providing analytics on plant growth to enhance efficiency. This innovative approach aims to reduce packaging, pesticides, and food waste, enabling users to cultivate fresh produce right where they live or work.

ZymoChem, Inc. is a biotechnology company based in Emeryville, California, founded in 2013. It specializes in the development of eco-friendly chemicals and bioprocesses using engineered microbes to convert renewable feedstocks, such as sugars, into industrial chemicals. The company’s bio-manufacturing platform aims to produce bio-based materials while minimizing carbon emissions during production, thereby supporting a carbon-efficient economy. By establishing cost-effective bioprocesses and novel biosynthetic pathways, ZymoChem enables clients to reduce production costs and enhance their competitiveness in the market. Through its innovative approach, the company contributes to sustainable manufacturing practices and the advancement of a real-zero economy.

Perfect Day, Inc. is a pioneering company based in Emeryville, California, that specializes in producing animal-free dairy products. Founded in 2014, the company creates milk, cheese, yogurt, milk proteins, and ice cream that are nutritionally identical to traditional dairy but are made through a fermentation process using plant-based sugars. This innovative approach allows Perfect Day to deliver products that retain the taste, texture, and nutrition of conventional dairy while eliminating concerns related to food safety, environmental impact, and animal welfare. The company's commitment to sustainability and compassion results in nutrient-dense alternatives that are vegan, free from antibiotics, cholesterol, and lactose, catering to a growing market for healthier and more ethical food options.

Chronus Health, Inc. is a company that specializes in developing a portable diagnostic platform aimed at delivering rapid point-of-care lab results, specifically for complete blood count and comprehensive metabolic panel tests. Founded in 2017 and based in Mountain View, California, the company's innovative system utilizes microfluidics and semiconductor technology, combined with data analytics, to provide healthcare providers with real-time test results. This capability allows for immediate diagnosis at the point of care, enhancing the efficiency of treatment and significantly improving patient outcomes. By enabling doctors to obtain lab results in minutes, Chronus Health facilitates timely decision-making in clinical settings.

Verdex Technologies Inc. is a company based in North Chesterfield, Virginia, that specializes in the design, patenting, and licensing of non-toxic nanofiber producing equipment for various applications, particularly in filtration and biomedical fields. The company leverages proprietary technology to mass produce advanced nanofibers, enabling the creation of high-quality nonwoven materials suitable for a wide range of uses, including engine filters, liquid filters, industrial air filters, and medical packaging. Verdex's innovative approach allows for the functionalization of nanofibers by incorporating nano-sized ingredients, enhancing the effectiveness of products like water filters. Committed to sustainability, Verdex utilizes biodegradable and bioresorbable polymers in its processes, ensuring that its production methods are environmentally friendly. Founded in 2011, the company aims to unlock the potential of nanofibers and improve quality of life through its advanced materials.

Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.

Tensorfield Agriculture, founded in 2018 and based in San Jose, California, develops innovative agricultural machinery tailored for specialty row crops. The company focuses on creating robots equipped with computer vision technology that perform selective, non-invasive weeding without the use of herbicides, utilizing thermal micro-dosing techniques. This approach addresses the growing concern of herbicide resistance, allowing farmers to cultivate crops sustainably while ensuring the continued supply of safe, fresh food. Tensorfield Agriculture is supported by the HAX hardware accelerator and has received investment from the global venture capital firm SOSV, positioning it at the forefront of agricultural innovation in a post-herbicide landscape.

Atlantic Fish Company is focused on producing cultivated seafood through cellular agriculture, operating from its headquarters in Raleigh-Durham, North Carolina. The company aims to provide sustainable seafood options by cultivating fish in a controlled environment. This innovative approach allows Atlantic Fish Company to offer fresh fish meat that maintains the natural taste while minimizing the environmental impact associated with traditional fishing practices. By leveraging cellular agriculture, the company seeks to meet the growing demand for sustainable protein sources.

Lingrove, LLC is a manufacturer of bio-composite materials based in San Francisco, California, founded in 2014. The company specializes in high-performance natural fiber composites made from plant-based materials, utilizing a proprietary process to create products that mimic the appearance and properties of wood. Its flagship product, Ekoa, combines flax linen fibers with resin derived from industrial waste, and is primarily used in the production of musical instruments, as well as in the furniture, transportation, and construction industries. Lingrove aims to address the challenges posed by diminishing wood supplies and seeks to reduce deforestation and the carbon footprint associated with the built environment by offering sustainable, carbon-negative alternatives.

Prellis Biologics, Inc. specializes in creating human tissues for drug development and the eventual production of human organs for transplantation. Founded in 2016 and based in San Francisco, California, the company employs advanced bioprinting technology to develop vascularized human tissues and organs, aiming to overcome the challenges associated with microvasculature. Its innovative products include TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X. Prellis Biologics also focuses on accurately replicating the human immune response through lymph node organoids, which can be utilized for various applications such as antibody discovery and immunogenicity assessment. By addressing critical issues in early-stage drug development and translational pharmacology, Prellis Biologics seeks to improve patient outcomes in healthcare.

Bite Inc. specializes in developing digital ordering solutions tailored for the hospitality industry, focusing primarily on quick service and fast casual restaurants. Founded in 2015 and headquartered in New York, the company offers innovative products such as bitekiosk, which provides kiosk ordering software for guests, and biteFLASH, a mobile interface that enables contactless ordering through QR codes. Additionally, Bite’s self-ordering kiosk software employs facial recognition technology to identify guests and learn their preferences, allowing for personalized recommendations. This approach not only enhances the guest experience but also helps restaurants build stronger customer relationships.

ViaBot Inc. develops autonomous outdoor robots tailored for commercial properties, including sports arenas, shopping malls, and corporate buildings. Founded in 2016 and based in Sunnyvale, California, the company offers its RUNO robots, which are capable of performing various outdoor maintenance tasks such as sweeping, lawn mowing, and providing security. These robots utilize vision-based technology to enhance security features, including the ability to scan license plates. ViaBot's solutions are designed with modular technology that allows for easy scheduling and long runtimes, ensuring round-the-clock monitoring and constant updates. The company's innovative approach aims to simplify outdoor maintenance for businesses, making operations more efficient and effective.

BioAesthetics LLC, founded in 2015 as a spin-out from Tulane University, is focused on developing innovative reconstruction options for breast cancer patients following mastectomies. The company specializes in a tissue-engineered nipple-areolar complex (NAC) that serves as an acellular graft to be used by plastic and reconstructive surgeons during the breast reconstruction phase. This product allows the patient's own cells to integrate with the graft, facilitating the regeneration of a natural nipple and areola. Currently in the pre-clinical phase, this patent-pending technology aims to provide a more effective and aesthetically pleasing solution for patients who have experienced incomplete or removed NACs due to illness, surgery, or congenital conditions. BioAesthetics is headquartered in Research Triangle Park, North Carolina.

Particle provides hardware and software tools to help users prototype, scale, and manage IoT products. Particle is an IoT device platform that enables businesses to easily add the power of connectivity to any product. From hardware to connectivity to device management and cloud, Particle provides developers with tools to prototype IoT solutions quickly as well as a reliable and secure platform for enterprises to scale. Over 150,000 product builders in more than 170 countries and half of the Fortune 500 have deployed connected IoT devices powered by Particle. Listed as one of Fast Company’s Most Innovative Companies of 2015 and named as a major player to watch in the IoT Landscape in IDC Marketscape’s 2018 Vendor Assessment, Particle’s customers include NASA, SpaceX, consumer hot tub manufacturer Jacuzzi, and coffee-brewing pioneer Keurig. Venture backed by Root Ventures, Spark Capital, and Qualcomm Ventures. Particle is based in San Francisco, CA and Shenzhen, China. Particle was founded on 2012.

Gatehouse Bio is a biotechnology company based in Waltham, Massachusetts, focused on the accelerated development of therapies utilizing small ribonucleic acid (RNA) and advanced bioinformatics. Founded in 2016, the company has developed a platform that employs artificial intelligence to identify error-free RNA biomarkers and discover disease-associated mutations. This platform enables precise classification of patient samples, which aids in the design of targeted therapeutics aimed at addressing various diseases, particularly in areas characterized by known heterogeneity such as fibrosis, inflammation, and neurodegeneration. By analyzing small RNA genes, Gatehouse Bio aims to unlock the potential for innovative treatments that could significantly enhance patient outcomes.

QuantumCyte, Inc. is a technology platform company based in Sunnyvale, California, that specializes in cell analysis systems aimed at predicting drug efficacy and improving cancer treatment outcomes. Founded in 2014, QuantumCyte develops automated microdissection solutions for molecular pathology, utilizing digital tissue maps to isolate regions of interest that contain important biomarkers. By harnessing artificial intelligence in digital pathology, the company enables healthcare providers to perform precise single-cell analysis, enhancing the understanding of immune system and cancer biology.

Avisa Myko Inc. is a biotechnology company based in San Francisco, California, specializing in the production of natural, water-soluble melanin. The company has developed a patented technology that allows for the large-scale and cost-effective manufacturing of melanin, which is used across various industries, including cosmetics, biomedicine, and environmental applications. Avisa Myko's melanin offers protection against ionizing radiation and is integrated into products such as latex, fabrics, laminated plastics, and glass. Additionally, the company is working on formulating a sunscreen that utilizes melanin as a natural ultraviolet blocker, eliminating the need for traditional chemical or mineral UV filters. By focusing on sustainable solutions, Avisa Myko aims to enhance human health and environmental safety through its innovative melanin products.

Bartesian Inc. is a Chicago-based company that manufactures a capsule-based cocktail machine, designed to enable users to create customized, bar-quality cocktails at home. Founded in 2014 and originally known as MaxMixology Inc., the company rebranded in 2015. The Bartesian machine operates using pre-mixed ingredient capsules, which include a variety of alcoholic choices, allowing consumers to prepare drinks such as martinis and cosmopolitans at the touch of a button. The system combines specialty pods containing liquors, bitters, extracts, and juice concentrates, making it possible for users to enjoy authentic cocktails without the need for extensive bartending skills.

Renewell is a company based in Bakersfield, California, that transforms inactive oil and gas wells into gravity-based energy storage systems. This innovative process involves lowering a weight connected to a regenerative winch down a repurposed wellbore, allowing for the storage of energy during periods of low demand and the release of electricity back to the grid when demand increases. By utilizing existing oil and gas infrastructure, Renewell aims to create a flexible and cost-effective energy storage network while significantly reducing greenhouse gas emissions. The company's technology focuses on zero-self-discharge renewable energy storage, contributing to a more sustainable energy future.

Arculus Solutions is focused on enhancing the safety and reliability of natural gas transmission pipelines by developing innovative hydrogen-barrier coatings. Headquartered in North Bethesda, Maryland, the company aims to future-proof infrastructure for the transportation of hydrogen, addressing the challenges posed by hydrogen embrittlement. Its coatings are applicable in diverse settings, including hydrogen fuel cell pipelines, storage tanks, and hydrogen-powered vehicles, thereby enabling the energy industry to mitigate risks associated with hydrogen transport and enhance overall safety.

Verdex Technologies Inc. is a company based in North Chesterfield, Virginia, that specializes in the design, patenting, and licensing of non-toxic nanofiber producing equipment for various applications, particularly in filtration and biomedical fields. The company leverages proprietary technology to mass produce advanced nanofibers, enabling the creation of high-quality nonwoven materials suitable for a wide range of uses, including engine filters, liquid filters, industrial air filters, and medical packaging. Verdex's innovative approach allows for the functionalization of nanofibers by incorporating nano-sized ingredients, enhancing the effectiveness of products like water filters. Committed to sustainability, Verdex utilizes biodegradable and bioresorbable polymers in its processes, ensuring that its production methods are environmentally friendly. Founded in 2011, the company aims to unlock the potential of nanofibers and improve quality of life through its advanced materials.

Unspun, Inc., founded in 2015 and based in San Francisco, California, specializes in the development of a platform that creates customized jeans using advanced body scanning technology, fit algorithms, and additive manufacturing. The company aims to address environmental concerns by reducing global carbon emissions through automated and localized manufacturing processes. Unspun’s innovative approach not only eliminates pattern-cutting waste and unsold inventory but also allows for the production of jeans in under ten minutes in a zero-waste manner. Their technology is showcased through the unspun.io platform, which provides digital customization solutions for various apparel brands. With a mission to make fashion more sustainable, Unspun is positioned at the intersection of robotics and digital apparel, striving to transform the industry with its unique approach to on-demand manufacturing.

Karma Biotechnologies, Inc. is a Los Angeles-based startup focused on developing therapies for autoimmune diseases, allergies, and food sensitivities. Founded in 2019, the company offers Xavines, a precision immunotherapy platform designed to address the critical need for antigen-specific therapies that target only the rogue immune cells responsible for these conditions. Unlike traditional treatments that rely on general immune suppression, Karma Biotechnologies aims to create tolerogenic immunotherapies that promote antigen-specific immune tolerance in vivo. By leveraging its expertise in immunology and lipid nanoparticle engineering, the company seeks to provide innovative solutions that enhance the treatment landscape for autoimmune diseases and related disorders.

California Cultured is a food company based in Davis, California, that specializes in producing sustainable, lab-grown cocoa through advanced cellular agriculture techniques. Founded in 2020, the company aims to create cocoa that is less bitter and requires less sugar, enhancing the taste while promoting health benefits. By stimulating cocoa cells with common food ingredients, California Cultured ensures the growth of premium-quality cocoa without the ethical and environmental issues associated with traditional cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious cocoa products that are both sustainable and socially responsible.

Pannex Therapeutics is a New York-based biopharmaceutical startup focused on developing innovative cancer therapies through the use of Pannexin 1 channel (Panx1) blockers. This new class of drugs aims to inhibit multiple pathways essential for the growth, spread, and survival of cancer cells. The company's research emphasizes high specificity for cancer cells, aiming to enhance treatment effectiveness while ensuring safety. By targeting these pathways, Pannex Therapeutics seeks to transform cancer therapy and provide options that minimize side effects and reduce the risk of addiction, particularly in the context of chronic pain management.

VIA BioFuels is a biotechnology research company based in Houston, Texas, founded in 2023. The company focuses on developing proprietary engineered yeast strains, specifically S. cerevisiae, to produce energy-dense drop-in fuels, particularly aromatic 3-methyl anisole (3-MA), from conventional ethanol feedstocks. VIA BioFuels' technology is designed to be scalable, leveraging existing ethanol production technologies and infrastructure. By producing high-purity synthetic aromatic substances, the company enhances the market potential of 3-MA, allowing it to be transformed into other valuable compounds. This innovation enables consumers to transition to alternative fuels without the constraints of blending restrictions, positioning VIA BioFuels as a significant player in the renewable energy sector.

AlkaLi Labs is a biotechnology research company based in San Francisco, California, established in 2023. The company focuses on developing biological solutions to harness domestic mineral resources. Currently operating in stealth mode, AlkaLi Labs aims to innovate in the field of biotechnology, leveraging biological processes to unlock valuable minerals.

Pear Bio is a biotechnology company based in Boston and London that focuses on developing precision medicine therapeutics for challenging cancer cases. By analyzing tumor biopsies and blood samples from patients, the company utilizes multi-omics approaches to identify new therapeutic targets. Their proprietary immune-microtumor system allows them to test the effectiveness of drug candidates directly on patient tumor samples. Pear Bio's innovative technology includes a specialized hydrogel that cultivates tumors outside the human body, effectively simulating drug resistance and streamlining the treatment selection process. This enables the identification of the most effective therapies for individual patients, thereby reducing the reliance on trial-and-error methods in cancer treatment.

Prime Roots is a San Francisco-based company founded in 2017 that specializes in plant-based food products, particularly meat and seafood alternatives. Utilizing koji mycelium, the company creates vegetarian offerings such as salmon burgers that replicate the taste, texture, and nutrition of traditional meat and seafood. By leveraging natural koji proteins, Prime Roots aims to reduce the reliance on carbon-intensive animal agriculture, providing both meat-eaters and vegans with protein-rich and sustainable food options. In addition to its product offerings, the company also organizes food events for its members.

League of Play is an interactive entertainment platform based in Los Angeles, California, that was founded in 2023. The platform focuses on creating competitions that unite top creators and athletes, aiming to bridge the gap between the online creator economy and live sports. By facilitating these competitions, League of Play generates interactive and viral content while offering substantial monetization opportunities through e-commerce, betting, and content licensing.

Forte Protein is a biotechnology company founded in 2021 and headquartered in Trumansburg, New York. The company focuses on developing an expression system to produce bio-identical animal proteins, aiming to provide a sustainable alternative to traditional animal agriculture. By offering a complete spectrum of plant-based proteins that mimic the characteristics of animal proteins, Forte Protein seeks to eliminate the carbon footprint associated with animal farming, thus catering to consumers looking for environmentally friendly protein options.

Geltor, Inc. is a biodesign company based in San Leandro, California, that specializes in producing bioactive, animal-free collagens and proteins for various applications in beauty, nutrition, and wellness. Established in 2015, Geltor offers innovative products such as Collume, which promotes skincare cellular regeneration and dermal synthesis, and HumaColl21, which enhances skin health by boosting collagen and elastin levels. Additionally, the company provides vegan collagen peptides and other novel proteins designed for functional food and nutraceutical formulations. Geltor's products are sustainably cultivated and clinically validated, allowing businesses to create effective, plant-based solutions that contribute to a more sustainable future.

Ten63 Therapeutics is a biotechnology company focused on developing innovative therapeutics for challenging diseases, particularly those involving targets previously considered undruggable. Founded in 2017 and based in Chapel Hill, North Carolina, the company utilizes its proprietary platform, COPPER, which integrates advanced artificial intelligence and state-of-the-art physical models to explore vast chemical spaces. By employing low-residual, machine learning-based computational chemistry alongside superlinear search algorithms, Ten63 Therapeutics aims to identify and optimize drug candidates effectively. Their approach includes proprietary scaffold redesign and hopping technology, enabling the screening of trillions of molecules to predict resistance and redesign antibodies. This combination of techniques positions Ten63 Therapeutics at the forefront of developing durable treatments for some of the most lethal diseases.

Amatec is an advanced materials company developing innovative construction solutions for the global housing and infrastructure sectors. Our flagship technology transforms industrial gypsum waste into fast-curing, high-strength, and low-carbon alternative concrete — enabling faster, greener, and more cost-effective construction. Amatec’s primary focus is on building a network of Microfactories: compact, modular production units capable of manufacturing high-quality precast housing panels and components. By leveraging phosphogypsum hemihydrate as a core raw material, Amatec helps industries repurpose mineral waste into sustainable building materials, significantly reducing environmental impact. Amatec's solutions are designed for scalability, automation, and rapid deployment, making them ideal for addressing major housing needs in the United States and elsewhere. The company is currently piloting its first microfactory and phosphogypsum processing lines in partnership with major industrial players.

MIMiC Systems designs solid-state heating and cooling systems at a building scale. It was founded in 2022 by Berardo Matalucci and Theodorian Borca-Tasciuc and is located in Brooklyn, New York.

Bite Inc. specializes in developing digital ordering solutions tailored for the hospitality industry, focusing primarily on quick service and fast casual restaurants. Founded in 2015 and headquartered in New York, the company offers innovative products such as bitekiosk, which provides kiosk ordering software for guests, and biteFLASH, a mobile interface that enables contactless ordering through QR codes. Additionally, Bite’s self-ordering kiosk software employs facial recognition technology to identify guests and learn their preferences, allowing for personalized recommendations. This approach not only enhances the guest experience but also helps restaurants build stronger customer relationships.

Stämm Biotech is a San Francisco-based company specializing in advanced bioproduction systems designed to address the scaling challenges in the biotech industry. Founded in 2014, Stämm has developed an innovative biomanufacturing solution that integrates microfluidics, electroporation, and robotics, resulting in a compact, all-in-one Bioprocessor. This system has demonstrated productivity levels at least 70 times greater than traditional bioreactors, enabling clients to miniaturize bioreactors and optimize conditions more efficiently. Stämm's technology incorporates various sensors to monitor biological, physical, and chemical variations throughout the bioprocess, facilitating a streamlined approach to microbial growth and monoclonal cell line development. By transforming large-scale biotech operations into a more manageable micro-factory network, Stämm aims to unlock significant market potential in the coming years.

Hidden Gems is a beverage company that offers Reveal, a first and only avocado seed beverage. The company's mission is to create beautiful, environmentally safe, and socially responsible upcycled products by discovering the hidden value in the food people would normally call trash. Hidden gems aims to reduce food waste, continue to create and support sustainable systems for sustainable living. The company was founded in 2019 and is based in Philadelphia, Pennsylvania.

Pulse Industrial, founded in 2017 and based in California, specializes in developing advanced monitoring solutions for industrial plants, particularly focusing on steam systems. The company has created a smart steam trap monitoring device that employs artificial intelligence to detect steam leaks by analyzing vibration and acoustic behavior. This technology, known as QALM, enhances visibility into potential failures, alerting maintenance personnel through low power wide area communication. Additionally, Pulse Industrial is exploring thermal applications utilizing phase change materials, further expanding its innovative offerings in the industrial sector. By enabling remote monitoring of critical components like steam traps, the company aims to improve safety and reduce fuel consumption across various industrial processes.

Windfall Bio is a company focused on developing a sustainable technology that captures and transforms methane emissions into organic fertilizer, addressing significant environmental issues associated with methane and synthetic fertilizers. Founded in 2022 and based in San Mateo, California, Windfall Bio utilizes methane-eating microbes to convert methane from various sources, including agriculture, oil and gas, and waste management, into valuable soil nutrients. This innovative solution not only helps industries reduce their methane footprint but also enhances operational efficiency and profitability, benefiting the planet and consumers alike. The company is backed by prominent venture capital firms, demonstrating strong investor confidence in its mission to tackle climate change through nature-based agricultural technology.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, DNALite utilizes innovative oral lipid nanoparticle technology to deliver mRNA and pDNA directly to intestinal stem cells. This approach targets the underlying causes of diseases such as Familial Adenomatous Polyposis, a hereditary form of colorectal cancer that often necessitates invasive surgeries in adolescents. By enabling the intestinal tract to secrete therapeutic proteins into the bloodstream, DNALite aims to transform conventional protein biologics into oral medications, potentially improving patient outcomes and accessibility to treatment.

Pear Bio is a biotechnology company based in Boston and London that focuses on developing precision medicine therapeutics for challenging cancer cases. By analyzing tumor biopsies and blood samples from patients, the company utilizes multi-omics approaches to identify new therapeutic targets. Their proprietary immune-microtumor system allows them to test the effectiveness of drug candidates directly on patient tumor samples. Pear Bio's innovative technology includes a specialized hydrogel that cultivates tumors outside the human body, effectively simulating drug resistance and streamlining the treatment selection process. This enables the identification of the most effective therapies for individual patients, thereby reducing the reliance on trial-and-error methods in cancer treatment.

Planetarians is a seed stage Climate/FoodTech company based in the United States that specializes in the development of innovative ingredient technologies aimed at producing affordable and healthy plant-based proteins. The company focuses on creating alternative meat products using by-products such as spent soybeans from vegetable oil extraction and spent yeast from beer fermentation. These carbon-negative meat alternatives not only serve as sustainable food options but also enable the fortification of various food products with natural protein and fiber derived from seeds. Planetarians has gained recognition in the industry, being featured in prominent publications and conferences for its contributions to sustainable food solutions.

BiomeSense, Inc. is a company that specializes in developing an integrated platform combining hardware, software, and data analytics to enhance the collection and analysis of microbiome data in clinical research. Founded in 2018 and based in Chicago, Illinois, BiomeSense has created the GutLab, an innovative "smart bathroom" system designed for continuous, at-home monitoring of the human gut microbiome. This technology, along with the MetaBiome time-series analytics platform, provides a comprehensive solution that enables researchers, patients, and consumers to track microbiome changes in real time and understand their impact on health outcomes. By generating and analyzing large-scale, longitudinal microbiome datasets, BiomeSense aims to discover and commercialize novel microbiome biomarkers, ultimately improving precision medicine and the development of microbiome-based therapeutics and products.

Atlantic Fish Company is focused on producing cultivated seafood through cellular agriculture, operating from its headquarters in Raleigh-Durham, North Carolina. The company aims to provide sustainable seafood options by cultivating fish in a controlled environment. This innovative approach allows Atlantic Fish Company to offer fresh fish meat that maintains the natural taste while minimizing the environmental impact associated with traditional fishing practices. By leveraging cellular agriculture, the company seeks to meet the growing demand for sustainable protein sources.

Tensorfield Agriculture, founded in 2018 and based in San Jose, California, develops innovative agricultural machinery tailored for specialty row crops. The company focuses on creating robots equipped with computer vision technology that perform selective, non-invasive weeding without the use of herbicides, utilizing thermal micro-dosing techniques. This approach addresses the growing concern of herbicide resistance, allowing farmers to cultivate crops sustainably while ensuring the continued supply of safe, fresh food. Tensorfield Agriculture is supported by the HAX hardware accelerator and has received investment from the global venture capital firm SOSV, positioning it at the forefront of agricultural innovation in a post-herbicide landscape.

Tandem is a company focused on providing electrification solutions for heavy-duty vehicles, specifically through its innovative instant hybrid electric refrigerated trailer. The company's approach aims to eliminate the upfront costs and risks typically associated with electric drivetrains, facilitating a smoother transition to sustainable practices within the supply chain. With offices located in New York and Florida, Tandem is dedicated to advancing the future of electrification and sustainability in the transportation industry.

Lief Therapeutics is a medical device company focused on improving at-home care for individuals suffering from post-traumatic stress disorder, depression, and anxiety. The company has developed a discreet biosensing patch that measures heart rate and breathing patterns with medical accuracy. This wearable device, known as Lief, helps users manage their stress responses through biofeedback exercises, allowing them to monitor their emotions and behaviors in real-time. Additionally, the device provides clinicians with insights into patient progress, enabling in-session training and tracking of psychological assessments. Lief Therapeutics also offers the Lief Health Score application, which records thoughts, emotions, and sensations, facilitating the tracking of daily progress and personalized practice exercises. Founded in 2014 and based in San Francisco, California, the company sells its products online.

FleetOperate is a truck driver marketplace that facilitates on-demand driving services for carriers and shippers. Founded in 2018 and based in Winnipeg, Manitoba, the platform allows users to book shipments from designated locations with registered truck drivers, enabling real-time tracking of their routes. This innovative approach addresses critical issues in the logistics industry, such as driver shortages, high turnover rates, and unutilized trucks, all while keeping operational costs low. By offering a Driver-as-a-Service model, FleetOperate enhances the efficiency of freight transport, ensuring that essential goods can be moved seamlessly and reliably.

BioCraft Pet Nutrition is a biotechnology company focused on creating sustainable and nutritious pet food for dogs and cats. Established in 2016 and based in Philadelphia, Pennsylvania, the company specializes in developing all-natural, organic products that incorporate innovative ingredients such as probiotics, nutritional yeast, and cultured meat. BioCraft aims to promote the health of pets while minimizing environmental impact and animal harm. The company's unique approach leverages green biotechnology to produce its offerings, which are available for purchase online. Through its commitment to sustainability and animal welfare, BioCraft Pet Nutrition stands out as a pioneer in the pet food industry.

Particle provides hardware and software tools to help users prototype, scale, and manage IoT products. Particle is an IoT device platform that enables businesses to easily add the power of connectivity to any product. From hardware to connectivity to device management and cloud, Particle provides developers with tools to prototype IoT solutions quickly as well as a reliable and secure platform for enterprises to scale. Over 150,000 product builders in more than 170 countries and half of the Fortune 500 have deployed connected IoT devices powered by Particle. Listed as one of Fast Company’s Most Innovative Companies of 2015 and named as a major player to watch in the IoT Landscape in IDC Marketscape’s 2018 Vendor Assessment, Particle’s customers include NASA, SpaceX, consumer hot tub manufacturer Jacuzzi, and coffee-brewing pioneer Keurig. Venture backed by Root Ventures, Spark Capital, and Qualcomm Ventures. Particle is based in San Francisco, CA and Shenzhen, China. Particle was founded on 2012.

Prolific Machines is a biotechnology company based in San Francisco, California, founded in 2020. It specializes in developing advanced cell technologies aimed at transforming the production of cells for sustainable applications, particularly in the cultivated meat industry. The company focuses on high-scale precision cell-differentiation techniques that enhance the efficiency, quality, reproducibility, and sustainability of cell production. Additionally, Prolific Machines is engaged in research and development efforts related to clean meat and cell therapies, utilizing innovative approaches to create better sustainable options. Through its work, the company aims to promote a healthier future for both humanity and the planet.

BioROSA Technologies Inc. is a Belmont, Massachusetts-based company focused on developing blood tests for Autism Spectrum Disorders (ASD). Founded in 2018, the company aims to establish a biologically-based standard of care for ASD through innovative diagnostic tools. These tools enable clinicians to identify individuals at risk for ASD by utilizing blood-based biomarkers and advanced machine learning techniques. BioROSA’s platform not only enhances early detection and diagnosis but also supports therapeutic developments by facilitating patient stratification and assessing pharmacodynamics in clinical trials. This comprehensive approach equips healthcare professionals with the necessary resources to improve patient outcomes through timely intervention.

Pneuma is a biotechnology company based in New York that focuses on creating sustainable products through innovative biotechnological processes. The company specializes in developing materials that harness carbon capture technology and photosynthesis, aiming to promote sustainable living and foster healthier relationships between people and their environment. By leveraging advanced biotechnology, Pneuma seeks to address ecological challenges and contribute to a more sustainable future.

Renewell is a company based in Bakersfield, California, that transforms inactive oil and gas wells into gravity-based energy storage systems. This innovative process involves lowering a weight connected to a regenerative winch down a repurposed wellbore, allowing for the storage of energy during periods of low demand and the release of electricity back to the grid when demand increases. By utilizing existing oil and gas infrastructure, Renewell aims to create a flexible and cost-effective energy storage network while significantly reducing greenhouse gas emissions. The company's technology focuses on zero-self-discharge renewable energy storage, contributing to a more sustainable energy future.

Harmony is a biotechnology startup that creates human breast milk protein-based infant nutrition designed to help human babies thrive. It is the world’s first dairy-free, allergen-free and environmentally friendly infant nutrition. Harmony Baby Nutrition was established in 2018 and is based in Boston, MA.

OneSkin Inc. is a biotechnology company focused on developing innovative solutions to enhance skin health and combat aging. Founded by a team of PhDs and longevity scientists, the company has created a proprietary peptide, OS-01, which has been validated to reduce the biological age of skin by minimizing the accumulation of aged cells, enhancing cellular repair, and fortifying the epidermal barrier. OneSkin offers a flagship product, the OS-01 Topical Supplement, which is designed to be suitable for all skin types and is made from high-quality vegan ingredients. In addition to its product line, OneSkin specializes in creating advanced 3D human skin models for research and testing purposes, providing in vitro services to assess the efficacy and safety of cosmetic ingredients without the use of animals. Incorporated in 2016 and based in San Francisco, OneSkin is dedicated to advancing the understanding of skin biology and developing effective anti-aging solutions.

Atlantic Fish Company is focused on producing cultivated seafood through cellular agriculture, operating from its headquarters in Raleigh-Durham, North Carolina. The company aims to provide sustainable seafood options by cultivating fish in a controlled environment. This innovative approach allows Atlantic Fish Company to offer fresh fish meat that maintains the natural taste while minimizing the environmental impact associated with traditional fishing practices. By leveraging cellular agriculture, the company seeks to meet the growing demand for sustainable protein sources.

Forte Protein is a biotechnology company founded in 2021 and headquartered in Trumansburg, New York. The company focuses on developing an expression system to produce bio-identical animal proteins, aiming to provide a sustainable alternative to traditional animal agriculture. By offering a complete spectrum of plant-based proteins that mimic the characteristics of animal proteins, Forte Protein seeks to eliminate the carbon footprint associated with animal farming, thus catering to consumers looking for environmentally friendly protein options.

Looking Glass Factory, established in 2014, is a technology company based in Brooklyn, New York, with a subsidiary in Hong Kong. It specializes in developing and manufacturing holographic displays, designed primarily for 3D creators. The company's flagship product, Looking Glass, is a desktop holographic display that combines light field and volumetric display technologies, enabling users to create, share, and interact with 3D content without the need for VR or AR headsets. Additionally, Looking Glass Factory offers volumetric printing services and software to manage its holographic displays. Its solutions cater to various industries, including drug discovery, medical visualization, experiential marketing, and 3D storytelling.

Swap Robotics, founded in 2019 and based in Kitchener, Ontario, specializes in manufacturing electric outdoor robots designed for vegetation cutting and snow plowing. The company offers commercial-ready robots that operate under a robotics-as-a-service model, allowing for versatility in outdoor maintenance tasks. Its innovative approach includes an in-house hydraulics platform that enables the easy swapping of attachments for various applications, making it possible for clients to automate their outdoor work with electric autonomous robots. By focusing on sustainable solutions, Swap Robotics aims to enhance efficiency in outdoor maintenance activities.

Helex, founded in 2021 and based in New York, specializes in developing innovative genomic medicines specifically for renal conditions. The company leverages its proprietary genomics data and bioinformatics platform to create, verify, and distribute therapy-specific guide RNAs (gRNAs). By employing data-driven deep-learning models and high throughput next-generation sequencing data from CRISPR edits on human cell lines, Helex provides reliable predictions and validations in-house. This approach supports clients in expediting the development of CRISPR-based drug discovery and cell and gene therapies, emphasizing non-viral targeted delivery and genome editing for kidney-related therapies.