SOSV
SOSV is a global venture capital firm that supports early-stage startups through active, founder-first development programs. Its flagship initiatives HAX and IndieBio provide facilities, engineering resources, services, and laboratory equipment to accelerate product development and prepare companies for subsequent funding rounds. SOSV focuses on deep technology across health, environmental, and cross-border software sectors, aiming to solve human and planetary health challenges. In addition to providing capital, the firm emphasizes intensive programmatic support to help portfolio companies move quickly from seed toward growth, including customer acquisition and scale. The firm operates globally with a bias toward startups targeting rapid international expansion, especially in Asia, and tends to back a small cohort of high-potential companies to accelerate their progress and attract leading investors.
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Past deals in Dental
Lura Health
Seed Round in 2023
Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.
BrickBuilt Therapeutics
Convertible Note in 2021
Microbiome-focused therapeutics for diseases of the oral cavity and their systemic effects
Oralta
Seed Round in 2021
Oralta is a United States-based company specializing in the production of probiotic supplements aimed at improving oral health. The company manufactures FRESH BREATH, a line of chewable tablets designed to combat bad breath by targeting odor-producing bacteria. These probiotics work by restoring a healthy balance of beneficial bacteria in the mouth, effectively eliminating the harmful germs responsible for unpleasant odors. In addition to addressing bad breath, Oralta's products also focus on broader oral health issues, such as tooth decay and gum disease. By inactivating the byproducts of these harmful bacteria, Oralta supports sustainable oral hygiene practices, allowing users to maintain their overall dental well-being.
BrickBuilt Therapeutics
Seed Round in 2020
Microbiome-focused therapeutics for diseases of the oral cavity and their systemic effects
Bravrr
Seed Round in 2020
Bravrr, LLC is a company based in Canon City, Colorado, founded in 2019, that specializes in the development of wearable diagnostic and therapeutic tools. Its flagship product, BruxRelief, is a smart biofeedback wearable designed to address bruxism disorder, which affects about one in three people yet remains largely undiagnosed. BruxRelief is an innovative headband equipped with advanced sensors and artificial intelligence to monitor and analyze users' clenching and grinding behaviors related to bruxism. By connecting to a smartphone app, it provides insights into nighttime bruxism activities and sleep patterns, enabling users to identify stress triggers and adopt measures to mitigate these harmful behaviors. Bravrr aims to revolutionize the bruxism market, which is valued at over $9 billion, by offering a user-friendly and effective alternative to traditional, complex diagnostic devices.
Lura Health
Convertible Note in 2020
Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.
Xixilab
Seed Round in 2020
Xixilab Limited specializes in orthodontics and teeth brightening products, focusing on enhancing dental care and improving smiles. The company offers a range of products, including a correction kit that features braces, a toothbrush, a mouth opener, a retainer, and wax, as well as a whitening kit containing blue light, brightening pens, a maintenance pen, a restorative pen, a teeth color card, and a user manual. Established in 2017 and headquartered in Hong Kong, Xixilab partners with dental clinics and professionals to provide both customized oral health products and affordable dental beauty services. The company's mission is to inspire confidence through improved smiles, emphasizing the importance of first impressions and the role of a confident smile in projecting a positive image.
Lura Health
Pre Seed Round in 2020
Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.
Bravrr
Pre Seed Round in 2019
Bravrr, LLC is a company based in Canon City, Colorado, founded in 2019, that specializes in the development of wearable diagnostic and therapeutic tools. Its flagship product, BruxRelief, is a smart biofeedback wearable designed to address bruxism disorder, which affects about one in three people yet remains largely undiagnosed. BruxRelief is an innovative headband equipped with advanced sensors and artificial intelligence to monitor and analyze users' clenching and grinding behaviors related to bruxism. By connecting to a smartphone app, it provides insights into nighttime bruxism activities and sleep patterns, enabling users to identify stress triggers and adopt measures to mitigate these harmful behaviors. Bravrr aims to revolutionize the bruxism market, which is valued at over $9 billion, by offering a user-friendly and effective alternative to traditional, complex diagnostic devices.
Mouth2Mouth
Seed Round in 2018
Mouth2Mouth is a healthcare startup that develops personalized probiotics for oral health. Based on microbiome data from thousands of healthy individuals, their AI-driven platform determines consortia of beneficial bacteria that fight widespread conditions such as tooth decay, gum disease, and bad breath.
The company is on a mission to improve oral hygiene and provide a solution to oral diseases by use of an all-natural process.
Hippo and Crate
Seed Round in 2018
Hippo & Crate Limited, established in 2016 and headquartered in Jing'an, China, specializes in the direct-to-consumer (D2C) distribution of high-quality oral care products. The company offers a subscription-based service for toothpaste, toothbrushes, mouthwash, and other complementary items, focusing on design, production, and distribution. Hippo & Crate aims to improve oral hygiene quality while promoting environmental responsibility through its products.
Kolibree
Series A in 2016
Kolibree develops smart dental care products. Their flagship is an AI-powered electric toothbrush that engages users and offers real-time feedback, aiming to enhance oral hygiene and prevent dental issues.
Kolibree
Convertible Note in 2015
Kolibree develops smart dental care products. Their flagship is an AI-powered electric toothbrush that engages users and offers real-time feedback, aiming to enhance oral hygiene and prevent dental issues.
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